Mcm10 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mcm10
Entrez Gene ID	307126
Full Name	minichromosome maintenance 10 replication initiation factor
General protein information	Preferred Names minichromosome maintenance 10 replication initiation factor Names protein MCM10 homolog minichromosome maintenance complex component 10 minichromosome maintenance deficient 10
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17q12.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001107366.1	NP_001100836.1	protein MCM10 homolog

Pathways from BioSystems

Homologies

Homo sapiens (human)	MCM10	NP_877428.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008723	XP_314834.4
Pan troglodytes (chimpanzee)	MCM10	XP_001140870.1
	MCM10	XP_001085751.2
Xenopus tropicalis (tropical clawed frog)	mcm10	NP_001016909.1
Canis lupus familiaris (dog)	MCM10	XP_544256.1
Mus musculus (house mouse)	Mcm10	NP_081566.2
Gallus gallus (chicken)	MCM10	XP_004937544.1
Danio rerio (zebrafish)	mcm10	NP_001019984.1
Drosophila melanogaster (fruit fly)	Mcm10	NP_610097.2
Bos taurus (cattle)	MCM10	XP_005214368.1
Rattus norvegicus (Norway rat)	Mcm10	NP_001100836.1

Gene Ontology
Bibliography

Related articles in PubMed

The RBBP6/ZBTB38/MCM10 axis regulates DNA replication and common fragile site stability.
Miotto B, Chibi M, Xie P, Koundrioukoff S, Moolman-Smook H, Pugh D, Debatisse M, He F, Zhang L, Defossez PA
Cell reports7(2)575-87(2014 Apr)

RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication.
Vannier JB, Sandhu S, Petalcorin MI, Wu X, Nabi Z, Ding H, Boulton SJ
Science (New York, N.Y.)342(6155)239-42(2013 Oct)

Targeted disruption of Mcm10 causes defective embryonic cell proliferation and early embryo lethality.
Lim HJ, Jeon Y, Jeon CH, Kim JH, Lee H
Biochimica et biophysica acta1813(10)1777-83(2011 Oct)

Hexameric ring structure of human MCM10 DNA replication factor.
Okorokov AL, Waugh A, Hodgkinson J, Murthy A, Hong HK, Leo E, Sherman MB, Stoeber K, Orlova EV, Williams GH
EMBO reports8(10)925-30(2007 Oct)

The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase.
Izumi M, Yanagi K, Mizuno T, Yokoi M, Kawasaki Y, Moon KY, Hurwitz J, Yatagai F, Hanaoka F
Nucleic acids research28(23)4769-77(2000 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Mcm10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mcm10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11174	NM_001107366.1 Latest version!	Rattus norvegicus minichromosome maintenance 10 replication initiation factor (Mcm10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mcm10 ( NM_001107366.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100836.1 Rattus norvegicus minichromosome maintenance 10 replication initiation factor (Mcm10), mRNA.

Price & Availability↑

CloneID	ORa11174
Clone ID Related Accession (Same CDS sequence)	NM_001107366.1
Accession Version	NM_001107366.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2670bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	protein MCM10 homolog
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473990.1. On or before Oct 4, 2007 this sequence version replaced XM_001071383.1, XM_225570.4. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689601, SAMEA2689605 [ECO:0000348] ##Evidence-Data-END##

ATGAATGTGG AGGAAGACGA CTTGTGTGTA CTGACATCTC TGCTGGAGGA GAACGAGGCA 
GCAGCCGTGC CCTGTGGCTC GGAGGAGAAT GAGAAGTCCT CGTCTCTGGA GGAAGGTGAC 
CCTGATGAAT TCGATGAGCT TTTTGATGCT GACGGCGATG GTGAATCTTA CACAGAAGAG 
GCCGACAGTG GGGAAGAGGG AAAGACCAGG GACCAGGAGG AACGGTTGGC CACTCTCTTT 
GGTGATGTGG AGGACCTAAC AGATGATGAA GTTCCTACAT CGCAAGTTGA AGACAGCAGT 
GTCCCCCCTG CTCCTGTTCG CAGCCGAGAG AAAACCAATC AGGAGTTGCA AGATGAATTG 
AAGAAGTTGC AAGAGCAGAT GAAATCCTTA CAGGAGCAGC TCAAAGCTGC ATCACTTCAA 
CAGCCTCCAA GTTCAGCCCC TTTGCACGAA CCACCTGGTG CATCTCTGCG GCCCCCACCT 
CAGGAGAAGA AAGTTAGGAG AATTCAGGAG TCGGTGTGCT TTTCTGCAGA GCTTGATGTC 
CCTGCCTTAC CCAGAGCCAA GCGGGTGGCT CGAGTGCCAA AGACTCCTGC AGAGTCATCT 
TCAAGGACAA GTGCACCCTC ACAACCACTG CGGGTTATTT CCAGTTTCTT AGAGCCTAAA 
AGCTCTCCGG CTAGGTCAAC AAGCATACCC TCACCTCAAG CTGTTCCTGG AAACAAATGC 
AGTGGGATGA CTAAAAATCA AAGCAAGGCA ACCCCCGGGA ATCCTGGGGA GCCGTCCCCG 
CAGGTTCCCC AGGTCTCTGT GGAAGCTTTC TCAGGCCTAC GCCTCAGGCG GCCTCGAGTC 
TCCTCCACAG AGATGAACAG GAAGATGACA GGTCGGAAAC TGATCAGACT GTCTCAGATC 
AAGGAGAAGA TGGCGACGGA GAACCTGGAA GAGACAGATT GGGTGACATT TGGGGTTATC 
CTGAGGAAGG TCACGCCACA GAGCGCTAAC AGTGGGAAAA CGTTTAGCAT CTGGAAACTG 
AACGACCTTC GTGACCTGAC CCAATGTGTG TCCTTGTTTC TGTTTGGAGA TGTTCACAAA 
GATCTCTGGA AGACAGAGCA AGGGACTGTC ATAGGGTTGC TCAACGCAAA TCCCATGAAG 
CCCAAAGAAG GCTTGACGGA GGTGTGCTTA TCTATCGATC ATCCTCAAAA AGTCTTAATT 
ATGGGAGAAG CTATGGATCT GGGGACCTGT AAAGCCAAGA AGAAGAATGG AGAGCCGTGC 
ACACAGACAG TCAACTTGCA TGACTGTGAG TACTGCCAGT ATCATATCCA GGCCCAGTAC 
AAGAAGCTTA GTGCAAAGCG GTCCGATCTG CAGTCCACTT TCTCCGGGGG ACGGATTCCC 
AAGAAGTTCC GCAGAGGCAC CAGCCTGAAG GAGCGGCTGT GTCAAGATGG TTTCTACTAC 
GGCGGGGTTT CTTCAGAATC CTTCGCAGCC TCCATGGCGG CAGCCATTGC TCCTAAGAAG 
AAGGTTCAAA CCACGCTGAC CAATCTGGTT GTGAGGGGCA CACGCTCAGT CATCCAGGAA 
ACAAAACAGA AGCTGGGAAT TCCCCAGAAG AGCTTGTCTT GCTCAGAGGA GTTCAGGGAA 
TTGATGGCCC TGCCCACATT TGGAGCCAGA AACTTACAAA AGCATTTAGC CAGAGCCAAG 
TCCTCAGGGA GCCCCAAACC TGCCATCCAG TCCATCTCAG CATCGGCCCT CTTGAAGCAG 
CAGAAACACC AGATGCTGGA AATGCGGAAG AGGAAATCAG AAGAAATACA GAAACGGTTC 
CTCCAGTCCT CAAGTGAGGT CCAGAGCGCA GCAGTGCCGT CCTCCTCTCG ACAGCCTGCT 
GCCCAGTCCC CTCGAACTGG GGCTGAGTTC CCCAGGTTGG AAGGAACGGA GGCCCCGTGG 
ACGCCCAAGC TGGGCAGAGG CATCTCAGAT GGGGACGACG TTCTCTTCTT TGATGAATCA 
CCACCACCAA AACCAAAGCT GAGCGCAGCA GCAGAAGCTA AAAAGTTAGC TGCTATTTCA 
AAATTGAGGG CAAAAGGCCA GATTCTTACA AAAGTAGATC CAAACAATAT TGTAAGGAGG 
CAAATGGACC CCCGAGATGT GCTGGGCGTG AAGGAGCGTG CAGAGAACAG CAACACGGTT 
TCTCCTGAAG ATGAACTGGA GCCCGCCAGG AAGAAAAGGA GAGAGCAGCT TGCGTACTTA 
GAGTCGGAGG AATTTCAGAA AATCCTAAAA GCAAAGTCCA AGCACACAGA CGTCCTGAAA 
GAGGCCGAGG CTGAGCTACA GAAATCCTAT TTTGATCCAC TGGTGAAAAA AGAACAGATG 
GAAGAAAAGA TGAGAGCCGT CCGCGAAGTG AAGTGCCGCG TGGTGACGTG CAGGAAGTGT 
GCCTACACCC ACTTCAAGCC TCTGGAGACC TGTGTCAGTG AACAGCATAA CCTCCACTGG 
CATGATGGTG TGAAAAGGTT TTTCAAATGT CCTTGTGGAA ACAGGACTAT CTCCCTGGAC 
AAGCTCCCAA ACAAGCACTG CCGTAACTGT GGCCTCTACA AGTGGGAACG GGATGGAATG 
CTAAAGGAGA AGACTGGTCC AAAGATCGGA GGAGAAACCC TGCTGCCACG AGGGGAAGAG 
CACGCTAAGT TTCTCAACAG CCTTAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100836.1
CDS	127..2796
Translation	MNVEEDDLCVLTSLLEENEAAAVPCGSEENEKSSSLEEGDPDEFDELFDADGDGESYTEEADSGEEGKTRDQEERLATLFGDVEDLTDDEVPTSQVEDSSVPPAPVRSREKTNQELQDELKKLQEQMKSLQEQLKAASLQQPPSSAPLHEPPGASLRPPPQEKKVRRIQESVCFSAELDVPALPRAKRVARVPKTPAESSSRTSAPSQPLRVISSFLEPKSSPARSTSIPSPQAVPGNKCSGMTKNQSKATPGNPGEPSPQVPQVSVEAFSGLRLRRPRVSSTEMNRKMTGRKLIRLSQIKEKMATENLEETDWVTFGVILRKVTPQSANSGKTFSIWKLNDLRDLTQCVSLFLFGDVHKDLWKTEQGTVIGLLNANPMKPKEGLTEVCLSIDHPQKVLIMGEAMDLGTCKAKKKNGEPCTQTVNLHDCEYCQYHIQAQYKKLSAKRSDLQSTFSGGRIPKKFRRGTSLKERLCQDGFYYGGVSSESFAASMAAAIAPKKKVQTTLTNLVVRGTRSVIQETKQKLGIPQKSLSCSEEFRELMALPTFGARNLQKHLARAKSSGSPKPAIQSISASALLKQQKHQMLEMRKRKSEEIQKRFLQSSSEVQSAAVPSSSRQPAAQSPRTGAEFPRLEGTEAPWTPKLGRGISDGDDVLFFDESPPPKPKLSAAAEAKKLAAISKLRAKGQILTKVDPNNIVRRQMDPRDVLGVKERAENSNTVSPEDELEPARKKRREQLAYLESEEFQKILKAKSKHTDVLKEAEAELQKSYFDPLVKKEQMEEKMRAVREVKCRVVTCRKCAYTHFKPLETCVSEQHNLHWHDGVKRFFKCPCGNRTISLDKLPNKHCRNCGLYKWERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK

Target ORF information:

RefSeq Version	NM_001107366.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus minichromosome maintenance 10 replication initiation factor (Mcm10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107366.1

ORF Insert Sequence:

ATGAATGTGG AGGAAGACGA CTTGTGTGTA CTGACATCTC TGCTGGAGGA GAACGAGGCA 
GCAGCCGTGC CCTGTGGCTC GGAGGAGAAT GAGAAGTCCT CGTCTCTGGA GGAAGGTGAC 
CCTGATGAAT TCGATGAGCT TTTTGATGCT GACGGCGATG GTGAATCTTA CACAGAAGAG 
GCCGACAGTG GGGAAGAGGG AAAGACCAGG GACCAGGAGG AACGGTTGGC CACTCTCTTT 
GGTGATGTGG AGGACCTAAC AGATGATGAA GTTCCTACAT CGCAAGTTGA AGACAGCAGT 
GTCCCCCCTG CTCCTGTTCG CAGCCGAGAG AAAACCAATC AGGAGTTGCA AGATGAATTG 
AAGAAGTTGC AAGAGCAGAT GAAATCCTTA CAGGAGCAGC TCAAAGCTGC ATCACTTCAA 
CAGCCTCCAA GTTCAGCCCC TTTGCACGAA CCACCTGGTG CATCTCTGCG GCCCCCACCT 
CAGGAGAAGA AAGTTAGGAG AATTCAGGAG TCGGTGTGCT TTTCTGCAGA GCTTGATGTC 
CCTGCCTTAC CCAGAGCCAA GCGGGTGGCT CGAGTGCCAA AGACTCCTGC AGAGTCATCT 
TCAAGGACAA GTGCACCCTC ACAACCACTG CGGGTTATTT CCAGTTTCTT AGAGCCTAAA 
AGCTCTCCGG CTAGGTCAAC AAGCATACCC TCACCTCAAG CTGTTCCTGG AAACAAATGC 
AGTGGGATGA CTAAAAATCA AAGCAAGGCA ACCCCCGGGA ATCCTGGGGA GCCGTCCCCG 
CAGGTTCCCC AGGTCTCTGT GGAAGCTTTC TCAGGCCTAC GCCTCAGGCG GCCTCGAGTC 
TCCTCCACAG AGATGAACAG GAAGATGACA GGTCGGAAAC TGATCAGACT GTCTCAGATC 
AAGGAGAAGA TGGCGACGGA GAACCTGGAA GAGACAGATT GGGTGACATT TGGGGTTATC 
CTGAGGAAGG TCACGCCACA GAGCGCTAAC AGTGGGAAAA CGTTTAGCAT CTGGAAACTG 
AACGACCTTC GTGACCTGAC CCAATGTGTG TCCTTGTTTC TGTTTGGAGA TGTTCACAAA 
GATCTCTGGA AGACAGAGCA AGGGACTGTC ATAGGGTTGC TCAACGCAAA TCCCATGAAG 
CCCAAAGAAG GCTTGACGGA GGTGTGCTTA TCTATCGATC ATCCTCAAAA AGTCTTAATT 
ATGGGAGAAG CTATGGATCT GGGGACCTGT AAAGCCAAGA AGAAGAATGG AGAGCCGTGC 
ACACAGACAG TCAACTTGCA TGACTGTGAG TACTGCCAGT ATCATATCCA GGCCCAGTAC 
AAGAAGCTTA GTGCAAAGCG GTCCGATCTG CAGTCCACTT TCTCCGGGGG ACGGATTCCC 
AAGAAGTTCC GCAGAGGCAC CAGCCTGAAG GAGCGGCTGT GTCAAGATGG TTTCTACTAC 
GGCGGGGTTT CTTCAGAATC CTTCGCAGCC TCCATGGCGG CAGCCATTGC TCCTAAGAAG 
AAGGTTCAAA CCACGCTGAC CAATCTGGTT GTGAGGGGCA CACGCTCAGT CATCCAGGAA 
ACAAAACAGA AGCTGGGAAT TCCCCAGAAG AGCTTGTCTT GCTCAGAGGA GTTCAGGGAA 
TTGATGGCCC TGCCCACATT TGGAGCCAGA AACTTACAAA AGCATTTAGC CAGAGCCAAG 
TCCTCAGGGA GCCCCAAACC TGCCATCCAG TCCATCTCAG CATCGGCCCT CTTGAAGCAG 
CAGAAACACC AGATGCTGGA AATGCGGAAG AGGAAATCAG AAGAAATACA GAAACGGTTC 
CTCCAGTCCT CAAGTGAGGT CCAGAGCGCA GCAGTGCCGT CCTCCTCTCG ACAGCCTGCT 
GCCCAGTCCC CTCGAACTGG GGCTGAGTTC CCCAGGTTGG AAGGAACGGA GGCCCCGTGG 
ACGCCCAAGC TGGGCAGAGG CATCTCAGAT GGGGACGACG TTCTCTTCTT TGATGAATCA 
CCACCACCAA AACCAAAGCT GAGCGCAGCA GCAGAAGCTA AAAAGTTAGC TGCTATTTCA 
AAATTGAGGG CAAAAGGCCA GATTCTTACA AAAGTAGATC CAAACAATAT TGTAAGGAGG 
CAAATGGACC CCCGAGATGT GCTGGGCGTG AAGGAGCGTG CAGAGAACAG CAACACGGTT 
TCTCCTGAAG ATGAACTGGA GCCCGCCAGG AAGAAAAGGA GAGAGCAGCT TGCGTACTTA 
GAGTCGGAGG AATTTCAGAA AATCCTAAAA GCAAAGTCCA AGCACACAGA CGTCCTGAAA 
GAGGCCGAGG CTGAGCTACA GAAATCCTAT TTTGATCCAC TGGTGAAAAA AGAACAGATG 
GAAGAAAAGA TGAGAGCCGT CCGCGAAGTG AAGTGCCGCG TGGTGACGTG CAGGAAGTGT 
GCCTACACCC ACTTCAAGCC TCTGGAGACC TGTGTCAGTG AACAGCATAA CCTCCACTGG 
CATGATGGTG TGAAAAGGTT TTTCAAATGT CCTTGTGGAA ACAGGACTAT CTCCCTGGAC 
AAGCTCCCAA ACAAGCACTG CCGTAACTGT GGCCTCTACA AGTGGGAACG GGATGGAATG 
CTAAAGGAGA AGACTGGTCC AAAGATCGGA GGAGAAACCC TGCTGCCACG AGGGGAAGAG 
CACGCTAAGT TTCTCAACAG CCTTAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The RBBP6/ZBTB38/MCM10 axis regulates DNA replication and common fragile site stability.
Cell reports7(2)575-87(2014 Apr)
Miotto B,Chibi M,Xie P,Koundrioukoff S,Moolman-Smook H,Pugh D,Debatisse M,He F,Zhang L,Defossez PA

RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication.
Science (New York, N.Y.)342(6155)239-42(2013 Oct)
Vannier JB,Sandhu S,Petalcorin MI,Wu X,Nabi Z,Ding H,Boulton SJ

Targeted disruption of Mcm10 causes defective embryonic cell proliferation and early embryo lethality.
Biochimica et biophysica acta1813(10)1777-83(2011 Oct)
Lim HJ,Jeon Y,Jeon CH,Kim JH,Lee H

Hexameric ring structure of human MCM10 DNA replication factor.
EMBO reports8(10)925-30(2007 Oct)
Okorokov AL,Waugh A,Hodgkinson J,Murthy A,Hong HK,Leo E,Sherman MB,Stoeber K,Orlova EV,Williams GH

The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase.
Nucleic acids research28(23)4769-77(2000 Dec)
Izumi M,Yanagi K,Mizuno T,Yokoi M,Kawasaki Y,Moon KY,Hurwitz J,Yatagai F,Hanaoka F