Hook3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hook3
Entrez Gene ID	306548
Full Name	hook microtubule-tethering protein 3
General protein information	Preferred Names hook microtubule-tethering protein 3 Names protein Hook homolog 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 16 Map Location: 16q12.4

mRNA and Protein(s)

mRNA	Protein	Name
NM_001136098.1	NP_001129570.1	protein Hook homolog 3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Hook3	NP_997542.1
Drosophila melanogaster (fruit fly)	hk	NP_476573.1
Pan troglodytes (chimpanzee)	HOOK3	XP_001145260.1
Gallus gallus (chicken)	HOOK3	XP_003643087.2
	HOOK3	XP_001099564.2
Anopheles gambiae (African malaria mosquito)	HOOK_ANOGA	XP_319596.4
Xenopus tropicalis (tropical clawed frog)	hook3	XP_004910960.1
Homo sapiens (human)	HOOK3	NP_115786.1
Canis lupus familiaris (dog)	HOOK3	XP_005629843.1
Bos taurus (cattle)	HOOK3	NP_001179529.1
Rattus norvegicus (Norway rat)	Hook3	NP_001129570.1

Gene Ontology
Bibliography

Related articles in PubMed

Assembly and activation of dynein-dynactin by the cargo adaptor protein Hook3.
Schroeder CM, Vale RD
The Journal of cell biology214(3)309-18(2016 Aug)

Hook3 interacts with PCM1 to regulate pericentriolar material assembly and the timing of neurogenesis.
Ge X, Frank CL, Calderon de Anda F, Tsai LH
Neuron65(2)191-203(2010 Jan)

An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex.
Xu L, Sowa ME, Chen J, Li X, Gygi SP, Harper JW
Molecular biology of the cell19(12)5059-71(2008 Dec)

The microtubule-binding protein Hook3 interacts with a cytoplasmic domain of scavenger receptor A.
Sano H, Ishino M, Kr?mer H, Shimizu T, Mitsuzawa H, Nishitani C, Kuroki Y
The Journal of biological chemistry282(11)7973-81(2007 Mar)

The Golgi-associated hook3 protein is a member of a novel family of microtubule-binding proteins.
Walenta JH, Didier AJ, Liu X, Kr?mer H
The Journal of cell biology152(5)923-34(2001 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Hook3 interacts with a cytoplasmic domain of scavenger receptor A
Title: The microtubule-binding protein Hook3 interacts with a cytoplasmic domain of scavenger receptor A.

The following Hook3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hook3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05772	NM_001136098.1 Latest version!	Rattus norvegicus hook microtubule-tethering protein 3 (Hook3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hook3 ( NM_001136098.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001129570.1 Rattus norvegicus hook microtubule-tethering protein 3 (Hook3), mRNA.

Price & Availability↑

CloneID	ORa05772
Clone ID Related Accession (Same CDS sequence)	NM_001136098.1
Accession Version	NM_001136098.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2157bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	protein Hook homolog 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473970.2. On or before Oct 23, 2008 this sequence version replaced XM_224952.4, XM_001062163.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTTTAACG TGGAGTCTGT GGAGCGGGTG GAGCTGTGCG AGAGCCTGCT CACTTGGATC 
CAGACCTTTA ATGTGGATAC ACCATGCCAG ACGGTGGAAG ACTTAACAAA TGGGGTTGTG 
ATGTCCCAGG TTCTTCAGAA GATAGATCCT GCATATTTCG ATGATAATTG GCTGAACAGA 
ATCAAGACTG AAGTAGGAGA CAACTGGAGG TTAAAGATTA GCAACTTAAA GAAAATTTTA 
AAAGGCATCT TGGATTATAA TCATGAGATT TTAGGGCAGC AGATTAATGA TTTTACCCTT 
CCTGATGTGA ACCTTATTGG GGAGCATTCG GATGCAGCAG AGCTCGGGAG GATGCTCCAG 
CTCATTCTAG GCTGTGCTGT GAACTGTGAA CAGAAGCAAG AGTACATTCA AGCCATTATG 
ATGATGGAGG AGTCTGTTCA GCATGTCGTC ATGACAGCCA TCCAAGAGCT AATGAGTAAA 
GAGTCTCCCG TCTCTGCTGG AAATGATGCC TATGTTGATC TCGATCGCCA GTTGAAGAAA 
ACTACAGAAG AACTAAATGA AGCTTTGTCA GCGAAGGAAG AAATTGCTCA AAGGTGCCAT 
GAATTGGATA TGCAGGTTGC AGCACTGCAA GAGGAGAAGA GTAGTTTATT GGCAGAAAAT 
CAGATATTAA TGGAACGACT CAATCAATCT GATTCTATAG AAGATCCCAA TAGTCCAGCA 
GGAAGAAGAC ATTTGCAACT TCAGACCCAG TTAGAACAGC TGCAAGAAGA AACATTCAGA 
CTAGAAGCAG CCAAAGACGA TTATCGAATA CGCTGTGAGG AGTTAGAAAA GGAAATCTCT 
GAGCTTCGGC AACAGAACGA TGAACTAACC ACTTTGGCCG ATGAGGCTCA GTCTCTAAAG 
GATGAAATAG ATGTTCTCAG ACACTCTTCT GATAAAGTAT CTAAACTAGA AGGTCAGGTC 
GAATCTTATA AAAAGAAGCT GGAAGACCTT GGAGATTTGA GACGGCAGGT TAAACTCCTA 
GAAGAGAAGA ATACGATGTA CATGCAGAAC ACTGTCAGCC TGGAGGAGGA ACTGAGGAAA 
GCTAATGCCG CCCGTGGTCA GCTCGAGACG TACAAGAGAC AGGTTGTAGA ACTGCAAAAT 
AGATTATCTG ACGAATCAAA GAAAGCAGAT AAGTTAGATT TTGAATATAA GCGGCTAAAG 
GAAAAAGTTG ATGGTCTTCA GAAAGAAAAG GATAGGTTAC GAACGGAAAG GGATTCTCTG 
AAGGAAACCA TTGAAGAGCT GCGTTGTGTG CAGGCTCAGG AGGGGCAGCT CACCACTCAA 
GGGTTAATGC CTCTGGGAAG CCAGGAGTCT TCAGACAGCC TTGCAGCAGA GATTGTCACA 
CCGGAAATCA GGGAGAAACT TATTCGTCTT CAGCATGAGA ATAAGATGTT AAAAATCAAC 
CAAGAGGGTT CAGACAATGA GAAAATTGCC TTATTGCAGA GCCTTCTAGA TGATGCAAAT 
CTTCGCAAGA ATGAGCTGGA GACAGAGAAC AGGCTTGTGA ATCAGAGACT TCTGGAAGTA 
CAGTCACAAG TAGAAGAACT GCAAAAATCT TTGCAGGATC AAGGCTCAAA AGCAGAAGAT 
TCAGTTCTTC TAAAAAAGAA GCTTGAAGAA CATCTAGAGA AGCTGCATGA AGCCAACAAT 
GAATTACAGA AAAAGAGAGC CATTATTGAA GATCTCGAGC CAAGATTTAA CAACAGCTCC 
TTAAGAATTG AAGAATTGCA AGAAGCTTTA CGGAAGAAAG AAGAAGAAAT GAAGCAAATG 
GAAGAACGCT ATAAAAAATA CCTGGAAAAA GCCAAAAGTG TTATCCGTAC ATTAGACCCT 
AAACAGAATC AAGGAGCAGC ACCAGAAATA CAGGCACTTA AAAACCAACT GCAGGAGCGC 
GATCGGCTCT TCCACTCATT AGAGAAAGAA TATGAGAAAA CGAAGACTCA AAGAGACATG 
GAGGAGAAAT ACATTGTTAG TGCCTGGTAC AATATGGGGA TGACACTACA TAAAAAGGCG 
GCTGAAGACA GACTAGCTAG CACAGGTTCA GGGCAGTCGT TTCTGGCTAG GCAAAGACAA 
GCAACCAGCA CAAGAAGATC CTACCCAGGC CATGTCCAGC CAGCCACAGC CAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129570.1
CDS	131..2287
Translation	MFNVESVERVELCESLLTWIQTFNVDTPCQTVEDLTNGVVMSQVLQKIDPAYFDDNWLNRIKTEVGDNWRLKISNLKKILKGILDYNHEILGQQINDFTLPDVNLIGEHSDAAELGRMLQLILGCAVNCEQKQEYIQAIMMMEESVQHVVMTAIQELMSKESPVSAGNDAYVDLDRQLKKTTEELNEALSAKEEIAQRCHELDMQVAALQEEKSSLLAENQILMERLNQSDSIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAARGQLETYKRQVVELQNRLSDESKKADKLDFEYKRLKEKVDGLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKLIRLQHENKMLKINQEGSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKLEEHLEKLHEANNELQKKRAIIEDLEPRFNNSSLRIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQGAAPEIQALKNQLQERDRLFHSLEKEYEKTKTQRDMEEKYIVSAWYNMGMTLHKKAAEDRLASTGSGQSFLARQRQATSTRRSYPGHVQPATAR

Target ORF information:

RefSeq Version	NM_001136098.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus hook microtubule-tethering protein 3 (Hook3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001136098.1

ORF Insert Sequence:

ATGTTTAACG TGGAGTCTGT GGAGCGGGTG GAGCTGTGCG AGAGCCTGCT CACTTGGATC 
CAGACCTTTA ATGTGGATAC ACCATGCCAG ACGGTGGAAG ACTTAACAAA TGGGGTTGTG 
ATGTCCCAGG TTCTTCAGAA GATAGATCCT GCATATTTCG ATGATAATTG GCTGAACAGA 
ATCAAGACTG AAGTAGGAGA CAACTGGAGG TTAAAGATTA GCAACTTAAA GAAAATTTTA 
AAAGGCATCT TGGATTATAA TCATGAGATT TTAGGGCAGC AGATTAATGA TTTTACCCTT 
CCTGATGTGA ACCTTATTGG GGAGCATTCG GATGCAGCAG AGCTCGGGAG GATGCTCCAG 
CTCATTCTAG GCTGTGCTGT GAACTGTGAA CAGAAGCAAG AGTACATTCA AGCCATTATG 
ATGATGGAGG AGTCTGTTCA GCATGTCGTC ATGACAGCCA TCCAAGAGCT AATGAGTAAA 
GAGTCTCCCG TCTCTGCTGG AAATGATGCC TATGTTGATC TCGATCGCCA GTTGAAGAAA 
ACTACAGAAG AACTAAATGA AGCTTTGTCA GCGAAGGAAG AAATTGCTCA AAGGTGCCAT 
GAATTGGATA TGCAGGTTGC AGCACTGCAA GAGGAGAAGA GTAGTTTATT GGCAGAAAAT 
CAGATATTAA TGGAACGACT CAATCAATCT GATTCTATAG AAGATCCCAA TAGTCCAGCA 
GGAAGAAGAC ATTTGCAACT TCAGACCCAG TTAGAACAGC TGCAAGAAGA AACATTCAGA 
CTAGAAGCAG CCAAAGACGA TTATCGAATA CGCTGTGAGG AGTTAGAAAA GGAAATCTCT 
GAGCTTCGGC AACAGAACGA TGAACTAACC ACTTTGGCCG ATGAGGCTCA GTCTCTAAAG 
GATGAAATAG ATGTTCTCAG ACACTCTTCT GATAAAGTAT CTAAACTAGA AGGTCAGGTC 
GAATCTTATA AAAAGAAGCT GGAAGACCTT GGAGATTTGA GACGGCAGGT TAAACTCCTA 
GAAGAGAAGA ATACGATGTA CATGCAGAAC ACTGTCAGCC TGGAGGAGGA ACTGAGGAAA 
GCTAATGCCG CCCGTGGTCA GCTCGAGACG TACAAGAGAC AGGTTGTAGA ACTGCAAAAT 
AGATTATCTG ACGAATCAAA GAAAGCAGAT AAGTTAGATT TTGAATATAA GCGGCTAAAG 
GAAAAAGTTG ATGGTCTTCA GAAAGAAAAG GATAGGTTAC GAACGGAAAG GGATTCTCTG 
AAGGAAACCA TTGAAGAGCT GCGTTGTGTG CAGGCTCAGG AGGGGCAGCT CACCACTCAA 
GGGTTAATGC CTCTGGGAAG CCAGGAGTCT TCAGACAGCC TTGCAGCAGA GATTGTCACA 
CCGGAAATCA GGGAGAAACT TATTCGTCTT CAGCATGAGA ATAAGATGTT AAAAATCAAC 
CAAGAGGGTT CAGACAATGA GAAAATTGCC TTATTGCAGA GCCTTCTAGA TGATGCAAAT 
CTTCGCAAGA ATGAGCTGGA GACAGAGAAC AGGCTTGTGA ATCAGAGACT TCTGGAAGTA 
CAGTCACAAG TAGAAGAACT GCAAAAATCT TTGCAGGATC AAGGCTCAAA AGCAGAAGAT 
TCAGTTCTTC TAAAAAAGAA GCTTGAAGAA CATCTAGAGA AGCTGCATGA AGCCAACAAT 
GAATTACAGA AAAAGAGAGC CATTATTGAA GATCTCGAGC CAAGATTTAA CAACAGCTCC 
TTAAGAATTG AAGAATTGCA AGAAGCTTTA CGGAAGAAAG AAGAAGAAAT GAAGCAAATG 
GAAGAACGCT ATAAAAAATA CCTGGAAAAA GCCAAAAGTG TTATCCGTAC ATTAGACCCT 
AAACAGAATC AAGGAGCAGC ACCAGAAATA CAGGCACTTA AAAACCAACT GCAGGAGCGC 
GATCGGCTCT TCCACTCATT AGAGAAAGAA TATGAGAAAA CGAAGACTCA AAGAGACATG 
GAGGAGAAAT ACATTGTTAG TGCCTGGTAC AATATGGGGA TGACACTACA TAAAAAGGCG 
GCTGAAGACA GACTAGCTAG CACAGGTTCA GGGCAGTCGT TTCTGGCTAG GCAAAGACAA 
GCAACCAGCA CAAGAAGATC CTACCCAGGC CATGTCCAGC CAGCCACAGC CAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Assembly and activation of dynein-dynactin by the cargo adaptor protein Hook3.
The Journal of cell biology214(3)309-18(2016 Aug)
Schroeder CM,Vale RD

Hook3 interacts with PCM1 to regulate pericentriolar material assembly and the timing of neurogenesis.
Neuron65(2)191-203(2010 Jan)
Ge X,Frank CL,Calderon de Anda F,Tsai LH

An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex.
Molecular biology of the cell19(12)5059-71(2008 Dec)
Xu L,Sowa ME,Chen J,Li X,Gygi SP,Harper JW

The microtubule-binding protein Hook3 interacts with a cytoplasmic domain of scavenger receptor A.
The Journal of biological chemistry282(11)7973-81(2007 Mar)
Sano H,Ishino M,Kr?mer H,Shimizu T,Mitsuzawa H,Nishitani C,Kuroki Y

The Golgi-associated hook3 protein is a member of a novel family of microtubule-binding proteins.
The Journal of cell biology152(5)923-34(2001 Mar)
Walenta JH,Didier AJ,Liu X,Kr?mer H

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Hook3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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