Acod1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Acod1
Entrez Gene ID	306127
Full Name	aconitate decarboxylase 1
Synonyms	Irg1,RGD1563454
General protein information	Preferred Names aconitate decarboxylase 1 Names cis-aconitate decarboxylase immunoresponsive 1 homolog immunoresponsive gene 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15q23

mRNA and Protein(s)

mRNA	Protein	Name
XM_006252440.3	XP_006252502.1	cis-aconitate decarboxylase isoform X1
NM_001107282.1	NP_001100752.1	cis-aconitate decarboxylase

Pathways from BioSystems

Homologies

Homo sapiens (human)	IRG1	NP_001245335.1
Canis lupus familiaris (dog)	IRG1	XP_542615.4
Bos taurus (cattle)	LOC504806	XP_002691944.2
Pan troglodytes (chimpanzee)	IRG1	XP_001137876.1
Xenopus tropicalis (tropical clawed frog)	irg1	XP_002931983.2
Mus musculus (house mouse)	Irg1	NP_032418.1
Gallus gallus (chicken)	IRG1	NP_001025992.1
	IRG1	XP_002800839.1
Rattus norvegicus (Norway rat)	Irg1	NP_001100752.1
Danio rerio (zebrafish)	irg1	NP_001119928.1

Gene Ontology
Bibliography

Related articles in PubMed

Immune responsive gene 1 (IRG1) promotes endotoxin tolerance by increasing A20 expression in macrophages through reactive oxygen species.
Li Y, Zhang P, Wang C, Han C, Meng J, Liu X, Xu S, Li N, Wang Q, Shi X, Cao X
The Journal of biological chemistry288(23)16225-34(2013 Jun)

Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.
Michelucci A, Cordes T, Ghelfi J, Pailot A, Reiling N, Goldmann O, Binz T, Wegner A, Tallam A, Rausell A, Buttini M, Linster CL, Medina E, Balling R, Hiller K
Proceedings of the National Academy of Sciences of the United States of America110(19)7820-5(2013 May)

Impact of lactobacilli on orally acquired listeriosis.
Archambaud C, Nahori MA, Soubigou G, B?cavin C, Laval L, Lechat P, Smokvina T, Langella P, Lecuit M, Cossart P
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)

The proinflammatory cytokine-induced IRG1 protein associates with mitochondria.
Degrandi D, Hoffmann R, Beuter-Gunia C, Pfeffer K
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research29(1)55-67(2009 Jan)

Immune-responsive gene 1 is a novel target of progesterone receptor and plays a critical role during implantation in the mouse.
Cheon YP, Xu X, Bagchi MK, Bagchi IC
Endocrinology144(12)5623-30(2003 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Acod1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Acod1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03227	NM_001107282.1 Latest version!	Rattus norvegicus aconitate decarboxylase 1 (Acod1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa36924	XM_006252440.3 Latest version!	Rattus norvegicus immunoresponsive gene 1 (Irg1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Acod1 ( NM_001107282.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100752.1 Rattus norvegicus aconitate decarboxylase 1 (Acod1), mRNA.

Price & Availability↑

CloneID	ORa03227
Clone ID Related Accession (Same CDS sequence)	NM_001107282.1
Accession Version	NM_001107282.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1467bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	cis-aconitate decarboxylase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473951.1. On or before Oct 4, 2007 this sequence version replaced XM_224476.4, XM_001076716.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689605 [ECO:0000348] ##Evidence-Data-END##

ATGATGCTCA AGTCTGTCAC AGAGAGCTTT GCCAGTATGA TTCACGGCTT GAGAGTGGGC 
CACCTGACAG ATGGCGTCAT TCAGAGGAGC AAGAGGATGA TCCTGGACTC TCTGGGCGTT 
GGTTTCCTGG GAACAGGCAC GGAAGTGTTC CATAACGTCA CCCAATATAG TAAAATCTAC 
AGTTCCAACA CCTCCAGCAC TGTTTGGGGT CGACCAGACT TCAGGCTCCC TCCCACATAT 
GCTGCTTTTG TTAACGGTGT TGCTATTCAC TCCATGGATT TTGATGACAC GTGGCACCCT 
GCCACCCACC CTTCCGGGGC TGTCCTACCT GTGCTCACAG CTTTATCGGA AGCCCTGCCC 
CAGACGCCAA AGTTTTCTGG CCTCGACCTG CTGCTGGCGT TCAGCGTTGG TATTGAAGTA 
CAAGGACGAT TGTTGCACTT CTCCAAGGAG GCCAAGGACA TACCAAAGAG GTTCCATCCT 
CCCTCTGTGG TGGGGACTCT GGGAAGTGCT GCTGCCACAT CCAAGTTTTT GGGGCTCAGC 
TTAACAAAGT GCCGTGAGGC CTTGGCTATT GCTGTTTCCC ATGCCGGGGC GCCCATAGCA 
AACGCTGCCA CTCAGACTAA GCCCCTTCAT ATCGGCAATG CAGCCAAGCA TGGGATGGAA 
GCCACATTTC TGGCAATGCT GGGCCTCCAA GGAAACAAAC AGATCTTGGA CCTGGGGTCA 
GGGTTTGGCG CCTTCTATGC CAACTACTCC CCCAAAGACC TTCCAAGCCT GGATTCTCAC 
ATCTGGCTCC TAGACCAGCA GGATGTGGCC TTTAAGAGCT TCCCGGCACA TCTGGCTACC 
CACTGGGTGG CAGACGCAGC CGCAGCTGTG AGAAAGCACC TCGTGACTTC AGAAAGAGCC 
CTGCTTCCTG CTGACCACAT CGAGAGAATC GTGCTCAGGA TCCCTGATGT CCAGTACGTA 
AACAGGCCCT TCCCGGACTC AGAGCATGAA GCCCGTCATT CCTTCCAGTA TGTGGCCTGT 
GCCACGCTGC TCGATGGTAG CGTCACTGTC CCATCCTTCT ATAGCCAGAA GGTCAACAGG 
CCTCAGGTGA AAGAGTTGCT CAAGAAGGTG GAGTTGGAAC ATCCTCCCGA CAACCTGCCA 
AGCTTCAACA CGCTCTACTG TGAAATAAGC ATCACTCTAA AGGATGGAAC CACTTTCACC 
GAGCGCTCTG ACACCTTCTA TGGTCACTGG AGGAAACCAC TGAGCCAGGA GGATCTGCAC 
AAGAAGTTCC GTGCCAATGC CTCAAAGATT CTAGGCGAGG ACACAGTAGA AAGCCTTATA 
ACGGTAGTAG AAAAACTAGA AGACCTAGAA GACTGCGCCA TGCTAACCAG ACTTCTGAAA 
GGACCCTCTG TCCAAGAGGA GGCTTCCAAA CTATCCAGCA TATTCTCATT CCATCACACA 
AGTTTGCCCA AGTTTACCAA TATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100752.1
CDS	97..1563
Translation	MMLKSVTESFASMIHGLRVGHLTDGVIQRSKRMILDSLGVGFLGTGTEVFHNVTQYSKIYSSNTSSTVWGRPDFRLPPTYAAFVNGVAIHSMDFDDTWHPATHPSGAVLPVLTALSEALPQTPKFSGLDLLLAFSVGIEVQGRLLHFSKEAKDIPKRFHPPSVVGTLGSAAATSKFLGLSLTKCREALAIAVSHAGAPIANAATQTKPLHIGNAAKHGMEATFLAMLGLQGNKQILDLGSGFGAFYANYSPKDLPSLDSHIWLLDQQDVAFKSFPAHLATHWVADAAAAVRKHLVTSERALLPADHIERIVLRIPDVQYVNRPFPDSEHEARHSFQYVACATLLDGSVTVPSFYSQKVNRPQVKELLKKVELEHPPDNLPSFNTLYCEISITLKDGTTFTERSDTFYGHWRKPLSQEDLHKKFRANASKILGEDTVESLITVVEKLEDLEDCAMLTRLLKGPSVQEEASKLSSIFSFHHTSLPKFTNI

Target ORF information:

RefSeq Version	NM_001107282.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus aconitate decarboxylase 1 (Acod1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107282.1

ORF Insert Sequence:

ATGATGCTCA AGTCTGTCAC AGAGAGCTTT GCCAGTATGA TTCACGGCTT GAGAGTGGGC 
CACCTGACAG ATGGCGTCAT TCAGAGGAGC AAGAGGATGA TCCTGGACTC TCTGGGCGTT 
GGTTTCCTGG GAACAGGCAC GGAAGTGTTC CATAACGTCA CCCAATATAG TAAAATCTAC 
AGTTCCAACA CCTCCAGCAC TGTTTGGGGT CGACCAGACT TCAGGCTCCC TCCCACATAT 
GCTGCTTTTG TTAACGGTGT TGCTATTCAC TCCATGGATT TTGATGACAC GTGGCACCCT 
GCCACCCACC CTTCCGGGGC TGTCCTACCT GTGCTCACAG CTTTATCGGA AGCCCTGCCC 
CAGACGCCAA AGTTTTCTGG CCTCGACCTG CTGCTGGCGT TCAGCGTTGG TATTGAAGTA 
CAAGGACGAT TGTTGCACTT CTCCAAGGAG GCCAAGGACA TACCAAAGAG GTTCCATCCT 
CCCTCTGTGG TGGGGACTCT GGGAAGTGCT GCTGCCACAT CCAAGTTTTT GGGGCTCAGC 
TTAACAAAGT GCCGTGAGGC CTTGGCTATT GCTGTTTCCC ATGCCGGGGC GCCCATAGCA 
AACGCTGCCA CTCAGACTAA GCCCCTTCAT ATCGGCAATG CAGCCAAGCA TGGGATGGAA 
GCCACATTTC TGGCAATGCT GGGCCTCCAA GGAAACAAAC AGATCTTGGA CCTGGGGTCA 
GGGTTTGGCG CCTTCTATGC CAACTACTCC CCCAAAGACC TTCCAAGCCT GGATTCTCAC 
ATCTGGCTCC TAGACCAGCA GGATGTGGCC TTTAAGAGCT TCCCGGCACA TCTGGCTACC 
CACTGGGTGG CAGACGCAGC CGCAGCTGTG AGAAAGCACC TCGTGACTTC AGAAAGAGCC 
CTGCTTCCTG CTGACCACAT CGAGAGAATC GTGCTCAGGA TCCCTGATGT CCAGTACGTA 
AACAGGCCCT TCCCGGACTC AGAGCATGAA GCCCGTCATT CCTTCCAGTA TGTGGCCTGT 
GCCACGCTGC TCGATGGTAG CGTCACTGTC CCATCCTTCT ATAGCCAGAA GGTCAACAGG 
CCTCAGGTGA AAGAGTTGCT CAAGAAGGTG GAGTTGGAAC ATCCTCCCGA CAACCTGCCA 
AGCTTCAACA CGCTCTACTG TGAAATAAGC ATCACTCTAA AGGATGGAAC CACTTTCACC 
GAGCGCTCTG ACACCTTCTA TGGTCACTGG AGGAAACCAC TGAGCCAGGA GGATCTGCAC 
AAGAAGTTCC GTGCCAATGC CTCAAAGATT CTAGGCGAGG ACACAGTAGA AAGCCTTATA 
ACGGTAGTAG AAAAACTAGA AGACCTAGAA GACTGCGCCA TGCTAACCAG ACTTCTGAAA 
GGACCCTCTG TCCAAGAGGA GGCTTCCAAA CTATCCAGCA TATTCTCATT CCATCACACA 
AGTTTGCCCA AGTTTACCAA TATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Acod1 ( XM_006252440.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006252502.1 Rattus norvegicus immunoresponsive gene 1 (Irg1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa36924
Clone ID Related Accession (Same CDS sequence)	XM_006252440.3
Accession Version	XM_006252440.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1194bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cis-aconitate decarboxylase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006252440.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATTTTG ATGACACGTG GCACCCTGCC ACCCACCCTT CCGGGGCTGT CCTACCTGTG 
CTCACAGCTT TATCGGAAGC CCTGCCCCAG ACGCCAAAGT TTTCTGGCCT CGACCTGCTG 
CTGGCGTTCA GCGTTGGTAT TGAAGTACAA GGACGATTGT TGCACTTCTC CAAGGAGGCC 
AAGGACATAC CAAAGAGGTT CCATCCTCCC TCTGTGGTGG GGACTCTGGG AAGTGCTGCT 
GCCACATCCA AGTTTTTGGG GCTCAGCTTA ACAAAGTGCC GTGAGGCCTT GGCTATTGCT 
GTTTCCCATG CCGGGGCGCC CATAGCAAAC GCTGCCACTC AGACTAAGCC CCTTCATATC 
GGCAATGCAG CCAAGCATGG GATGGAAGCC ACATTTCTGG CAATGCTGGG CCTCCAAGGA 
AACAAACAGA TCTTGGACCT GGGGTCAGGG TTTGGCGCCT TCTATGCCAA CTACTCCCCC 
AAAGACCTTC CAAGCCTGGA TTCTCACATC TGGCTCCTAG ACCAGCAGGA TGTGGCCTTT 
AAGAGCTTCC CGGCACATCT GGCTACCCAC TGGGTGGCAG ACGCAGCCGC AGCTGTGAGA 
AAGCACCTCG TGACTTCAGA AAGAGCCCTG CTTCCTGCTG ACCACATCGA GAGAATCGTG 
CTCAGGATCC CTGATGTCCA GTACGTAAAC AGGCCCTTCC CGGACTCAGA GCATGAAGCC 
CGTCATTCCT TCCAGTATGT GGCCTGTGCC ACGCTGCTCG ATGGTAGCGT CACTGTCCCA 
TCCTTCTATA GCCAGAAGGT CAACAGGCCT CAGGTGAAAG AGTTGCTCAA GAAGGTGGAG 
TTGGAACATC CTCCCGACAA CCTGCCAAGC TTCAACACGC TCTACTGTGA AATAAGCATC 
ACTCTAAAGG ATGGAACCAC TTTCACCGAG CGCTCTGACA CCTTCTATGG TCACTGGAGG 
AAACCACTGA GCCAGGAGGA TCTGCACAAG AAGTTCCGTG CCAATGCCTC AAAGATTCTA 
GGCGAGGACA CAGTAGAAAG CCTTATAACG GTAGTAGAAA AACTAGAAGA CCTAGAAGAC 
TGCGCCATGC TAACCAGACT TCTGAAAGGA CCCTCTGTCC AAGAGGAGGC TTCCAAACTA 
TCCAGCATAT TCTCATTCCA TCACACAAGT TTGCCCAAGT TTACCAATAT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006252502.1
CDS	571..1764
Translation	MDFDDTWHPATHPSGAVLPVLTALSEALPQTPKFSGLDLLLAFSVGIEVQGRLLHFSKEAKDIPKRFHPPSVVGTLGSAAATSKFLGLSLTKCREALAIAVSHAGAPIANAATQTKPLHIGNAAKHGMEATFLAMLGLQGNKQILDLGSGFGAFYANYSPKDLPSLDSHIWLLDQQDVAFKSFPAHLATHWVADAAAAVRKHLVTSERALLPADHIERIVLRIPDVQYVNRPFPDSEHEARHSFQYVACATLLDGSVTVPSFYSQKVNRPQVKELLKKVELEHPPDNLPSFNTLYCEISITLKDGTTFTERSDTFYGHWRKPLSQEDLHKKFRANASKILGEDTVESLITVVEKLEDLEDCAMLTRLLKGPSVQEEASKLSSIFSFHHTSLPKFTNI

Target ORF information:

RefSeq Version	XM_006252440.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus immunoresponsive gene 1 (Irg1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006252440.3

ORF Insert Sequence:

ATGGATTTTG ATGACACGTG GCACCCTGCC ACCCACCCTT CCGGGGCTGT CCTACCTGTG 
CTCACAGCTT TATCGGAAGC CCTGCCCCAG ACGCCAAAGT TTTCTGGCCT CGACCTGCTG 
CTGGCGTTCA GCGTTGGTAT TGAAGTACAA GGACGATTGT TGCACTTCTC CAAGGAGGCC 
AAGGACATAC CAAAGAGGTT CCATCCTCCC TCTGTGGTGG GGACTCTGGG AAGTGCTGCT 
GCCACATCCA AGTTTTTGGG GCTCAGCTTA ACAAAGTGCC GTGAGGCCTT GGCTATTGCT 
GTTTCCCATG CCGGGGCGCC CATAGCAAAC GCTGCCACTC AGACTAAGCC CCTTCATATC 
GGCAATGCAG CCAAGCATGG GATGGAAGCC ACATTTCTGG CAATGCTGGG CCTCCAAGGA 
AACAAACAGA TCTTGGACCT GGGGTCAGGG TTTGGCGCCT TCTATGCCAA CTACTCCCCC 
AAAGACCTTC CAAGCCTGGA TTCTCACATC TGGCTCCTAG ACCAGCAGGA TGTGGCCTTT 
AAGAGCTTCC CGGCACATCT GGCTACCCAC TGGGTGGCAG ACGCAGCCGC AGCTGTGAGA 
AAGCACCTCG TGACTTCAGA AAGAGCCCTG CTTCCTGCTG ACCACATCGA GAGAATCGTG 
CTCAGGATCC CTGATGTCCA GTACGTAAAC AGGCCCTTCC CGGACTCAGA GCATGAAGCC 
CGTCATTCCT TCCAGTATGT GGCCTGTGCC ACGCTGCTCG ATGGTAGCGT CACTGTCCCA 
TCCTTCTATA GCCAGAAGGT CAACAGGCCT CAGGTGAAAG AGTTGCTCAA GAAGGTGGAG 
TTGGAACATC CTCCCGACAA CCTGCCAAGC TTCAACACGC TCTACTGTGA AATAAGCATC 
ACTCTAAAGG ATGGAACCAC TTTCACCGAG CGCTCTGACA CCTTCTATGG TCACTGGAGG 
AAACCACTGA GCCAGGAGGA TCTGCACAAG AAGTTCCGTG CCAATGCCTC AAAGATTCTA 
GGCGAGGACA CAGTAGAAAG CCTTATAACG GTAGTAGAAA AACTAGAAGA CCTAGAAGAC 
TGCGCCATGC TAACCAGACT TCTGAAAGGA CCCTCTGTCC AAGAGGAGGC TTCCAAACTA 
TCCAGCATAT TCTCATTCCA TCACACAAGT TTGCCCAAGT TTACCAATAT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Immune responsive gene 1 (IRG1) promotes endotoxin tolerance by increasing A20 expression in macrophages through reactive oxygen species.
The Journal of biological chemistry288(23)16225-34(2013 Jun)
Li Y,Zhang P,Wang C,Han C,Meng J,Liu X,Xu S,Li N,Wang Q,Shi X,Cao X

Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.
Proceedings of the National Academy of Sciences of the United States of America110(19)7820-5(2013 May)
Michelucci A,Cordes T,Ghelfi J,Pailot A,Reiling N,Goldmann O,Binz T,Wegner A,Tallam A,Rausell A,Buttini M,Linster CL,Medina E,Balling R,Hiller K

Impact of lactobacilli on orally acquired listeriosis.
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)
Archambaud C,Nahori MA,Soubigou G,B?cavin C,Laval L,Lechat P,Smokvina T,Langella P,Lecuit M,Cossart P

The proinflammatory cytokine-induced IRG1 protein associates with mitochondria.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research29(1)55-67(2009 Jan)
Degrandi D,Hoffmann R,Beuter-Gunia C,Pfeffer K

Immune-responsive gene 1 is a novel target of progesterone receptor and plays a critical role during implantation in the mouse.
Endocrinology144(12)5623-30(2003 Dec)
Cheon YP,Xu X,Bagchi MK,Bagchi IC