Peli1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Peli1
Entrez Gene ID	305549
Full Name	pellino E3 ubiquitin protein ligase 1
General protein information	Preferred Names pellino E3 ubiquitin protein ligase 1 Names E3 ubiquitin-protein ligase pellino homolog 1 pellino 1 pellino homolog 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14q22

mRNA and Protein(s)

mRNA	Protein	Name
XM_017599243.1	XP_017454732.1	E3 ubiquitin-protein ligase pellino homolog 1 isoform X1
NM_001100565.1	NP_001094035.1	E3 ubiquitin-protein ligase pellino homolog 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PELI1	XP_001153695.2
	PELI1	XP_001085049.2
Danio rerio (zebrafish)	peli1b	NP_001071069.2
Mus musculus (house mouse)	Peli1	NP_075813.2
Homo sapiens (human)	PELI1	NP_065702.2
Rattus norvegicus (Norway rat)	Peli1	NP_001094035.1
Canis lupus familiaris (dog)	PELI1	XP_005626215.1
Bos taurus (cattle)	PELI1	NP_001071472.1
Gallus gallus (chicken)	PELI1	NP_001012890.1
Xenopus tropicalis (tropical clawed frog)	peli2	NP_001096406.1

Gene Ontology
Bibliography

Related articles in PubMed

Pellino1-mediated TGF-?1 synthesis contributes to mechanical stress induced cardiac fibroblast activation.
Song J, Zhu Y, Li J, Liu J, Gao Y, Ha T, Que L, Liu L, Zhu G, Chen Q, Xu Y, Li C, Li Y
Journal of molecular and cellular cardiology79145-56(2015 Feb)

The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity.
Chang M, Jin W, Chang JH, Xiao Y, Brittain GC, Yu J, Zhou X, Wang YH, Cheng X, Li P, Rabinovich BA, Hwu P, Sun SC
Nature immunology12(10)1002-9(2011 Aug)

Interleukin-1 (IL-1) pathway.
Weber A, Wasiliew P, Kracht M
Science signaling3(105)cm1(2010 Jan)

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production.
Chang M, Jin W, Sun SC
Nature immunology10(10)1089-95(2009 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Pellino1 silencing prevented the binding of NF-kappaB and AP-1 to the promoter region of transforming growth factor-beta1 (TGF-beta1) thus dampening TGF-beta1 transactivation.
Title: Pellino1-mediated TGF-?1 synthesis contributes to mechanical stress induced cardiac fibroblast activation.

The following Peli1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Peli1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03151	NM_001100565.1 Latest version!	Rattus norvegicus pellino E3 ubiquitin protein ligase 1 (Peli1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa03151	XM_017599243.1 Latest version!	Rattus norvegicus pellino E3 ubiquitin protein ligase 1 (Peli1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Peli1 ( NM_001100565.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001094035.1 Rattus norvegicus pellino E3 ubiquitin protein ligase 1 (Peli1), mRNA.

Price & Availability↑

CloneID	ORa03151
Clone ID Related Accession (Same CDS sequence)	XM_017599243.1 , NM_001100565.1
Accession Version	NM_001100565.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1257bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	E3 ubiquitin-protein ligase pellino homolog 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB770819.1, BC166745.1 and BC092604.1. On or before Sep 7, 2008 this sequence version replaced XM_001070955.1, XM_001060915.1. ##Evidence-Data-START## Transcript exon combination :: BC166745.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTTTTCTC CTGATCAAGA AAATCATCCT TCCAAAGCCC CAGTAAAATA TGGCGAACTC 
ATTGTCTTAG GGTATAATGG GTCTCTCCCA AACGGCGACA GAGGAAGGAG GAAAAGTAGG 
TTTGCTTTGT TTAAAAGACC TAAGGCAAAT GGGGTGAAGC CTAGCACCGT GCACATTGCA 
TGCACTCCTC AGGCCGCCAA GGCAATAAGC AACAAGGACC AGCATAGCAT ATCGTATACT 
TTATCTCGAG CCCAGACAGT GGTGGTTGAA TATACTCACG ACAGCAACAC TGATATGTTT 
CAGATTGGCC GGTCAACTGA AAGTCCTATT GATTTTGTGG TAACTGACAC AGTTCCTGGA 
AGTCAGAGTA ATTCCGACAC GCAGTCCGTA CAAAGCACTA TATCGAGGTT TGCCTGTAGG 
ATCATTTGTG AACGCAATCC TCCCTTTACA GCTCGGATTT ATGCTGCAGG ATTTGATTCA 
TCAAAAAACA TCTTTCTTGG GGAGAAGGCT GCCAAATGGA AGACGTCCGA CGGGCAGATG 
GACGGCCTGA CCACCAATGG AGTTCTTGTG ATGCATCCAC GCGATGGGTT CACAGAAGAC 
TCCAAGCCTG GAATATGGAG AGAGATATCC GTATGTGGGA ACGTCTTCAG TCTGCGTGAA 
ACCAGATCAG CGCAACAGAG AGGAAAGATG GTGGAAATCG AAACCAATCA GCTGCAAGAT 
GGCTCCTTAA TCGACCTCTG TGGTGCAACC CTGCTGTGGC GCACAGCAGA AGGCCTTTCC 
CACACCCCTA CTGTGAAACA CTTAGAAGCT CTGAGACAGG AGATCAATGC AGCTCGGCCT 
CAGTGCCCTG TAGGCTTCAA CACACTAGCC TTCCCCAGCA TGAAGAGGAA AGATGTTGTA 
GATGAGAAGC AACCATGGGT ATATCTGAAC TGCGGCCATG TTCATGGTTA CCATAACTGG 
GGAAACAAGG AAGAACGTGA CGGCAAAGAT CGTGAATGTC CTATGTGTAG GTCTGTTGGT 
CCCTATGTCC CTCTGTGGCT TGGATGTGAA GCTGGATTTT ATGTGGACGC CGGCCCTCCC 
ACCCATGCCT TTAGCCCCTG TGGGCATGTG TGTTCAGAAA AGACAACGGC TTACTGGTCC 
CAGATCCCGC TTCCTCATGG TACGCACACT TTTCACGCAG CCTGTCCCTT CTGTGCACAT 
CAGTTGGCTG GTGAACAAGG CTATATCAGA CTTATTTTCC AAGGACCTCT AGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001094035.1
CDS	280..1536
Translation	MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIACTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGVLVMHPRDGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQLQDGSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVVDEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD

Target ORF information:

RefSeq Version	NM_001100565.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pellino E3 ubiquitin protein ligase 1 (Peli1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100565.1

ORF Insert Sequence:

ATGTTTTCTC CTGATCAAGA AAATCATCCT TCCAAAGCCC CAGTAAAATA TGGCGAACTC 
ATTGTCTTAG GGTATAATGG GTCTCTCCCA AACGGCGACA GAGGAAGGAG GAAAAGTAGG 
TTTGCTTTGT TTAAAAGACC TAAGGCAAAT GGGGTGAAGC CTAGCACCGT GCACATTGCA 
TGCACTCCTC AGGCCGCCAA GGCAATAAGC AACAAGGACC AGCATAGCAT ATCGTATACT 
TTATCTCGAG CCCAGACAGT GGTGGTTGAA TATACTCACG ACAGCAACAC TGATATGTTT 
CAGATTGGCC GGTCAACTGA AAGTCCTATT GATTTTGTGG TAACTGACAC AGTTCCTGGA 
AGTCAGAGTA ATTCCGACAC GCAGTCCGTA CAAAGCACTA TATCGAGGTT TGCCTGTAGG 
ATCATTTGTG AACGCAATCC TCCCTTTACA GCTCGGATTT ATGCTGCAGG ATTTGATTCA 
TCAAAAAACA TCTTTCTTGG GGAGAAGGCT GCCAAATGGA AGACGTCCGA CGGGCAGATG 
GACGGCCTGA CCACCAATGG AGTTCTTGTG ATGCATCCAC GCGATGGGTT CACAGAAGAC 
TCCAAGCCTG GAATATGGAG AGAGATATCC GTATGTGGGA ACGTCTTCAG TCTGCGTGAA 
ACCAGATCAG CGCAACAGAG AGGAAAGATG GTGGAAATCG AAACCAATCA GCTGCAAGAT 
GGCTCCTTAA TCGACCTCTG TGGTGCAACC CTGCTGTGGC GCACAGCAGA AGGCCTTTCC 
CACACCCCTA CTGTGAAACA CTTAGAAGCT CTGAGACAGG AGATCAATGC AGCTCGGCCT 
CAGTGCCCTG TAGGCTTCAA CACACTAGCC TTCCCCAGCA TGAAGAGGAA AGATGTTGTA 
GATGAGAAGC AACCATGGGT ATATCTGAAC TGCGGCCATG TTCATGGTTA CCATAACTGG 
GGAAACAAGG AAGAACGTGA CGGCAAAGAT CGTGAATGTC CTATGTGTAG GTCTGTTGGT 
CCCTATGTCC CTCTGTGGCT TGGATGTGAA GCTGGATTTT ATGTGGACGC CGGCCCTCCC 
ACCCATGCCT TTAGCCCCTG TGGGCATGTG TGTTCAGAAA AGACAACGGC TTACTGGTCC 
CAGATCCCGC TTCCTCATGG TACGCACACT TTTCACGCAG CCTGTCCCTT CTGTGCACAT 
CAGTTGGCTG GTGAACAAGG CTATATCAGA CTTATTTTCC AAGGACCTCT AGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Peli1 ( XM_017599243.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017454732.1 Rattus norvegicus pellino E3 ubiquitin protein ligase 1 (Peli1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa03151
Clone ID Related Accession (Same CDS sequence)	XM_017599243.1 , NM_001100565.1
Accession Version	XM_017599243.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1257bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	E3 ubiquitin-protein ligase pellino homolog 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTTTCTC CTGATCAAGA AAATCATCCT TCCAAAGCCC CAGTAAAATA TGGCGAACTC 
ATTGTCTTAG GGTATAATGG GTCTCTCCCA AACGGCGACA GAGGAAGGAG GAAAAGTAGG 
TTTGCTTTGT TTAAAAGACC TAAGGCAAAT GGGGTGAAGC CTAGCACCGT GCACATTGCA 
TGCACTCCTC AGGCCGCCAA GGCAATAAGC AACAAGGACC AGCATAGCAT ATCGTATACT 
TTATCTCGAG CCCAGACAGT GGTGGTTGAA TATACTCACG ACAGCAACAC TGATATGTTT 
CAGATTGGCC GGTCAACTGA AAGTCCTATT GATTTTGTGG TAACTGACAC AGTTCCTGGA 
AGTCAGAGTA ATTCCGACAC GCAGTCCGTA CAAAGCACTA TATCGAGGTT TGCCTGTAGG 
ATCATTTGTG AACGCAATCC TCCCTTTACA GCTCGGATTT ATGCTGCAGG ATTTGATTCA 
TCAAAAAACA TCTTTCTTGG GGAGAAGGCT GCCAAATGGA AGACGTCCGA CGGGCAGATG 
GACGGCCTGA CCACCAATGG AGTTCTTGTG ATGCATCCAC GCGATGGGTT CACAGAAGAC 
TCCAAGCCTG GAATATGGAG AGAGATATCC GTATGTGGGA ACGTCTTCAG TCTGCGTGAA 
ACCAGATCAG CGCAACAGAG AGGAAAGATG GTGGAAATCG AAACCAATCA GCTGCAAGAT 
GGCTCCTTAA TCGACCTCTG TGGTGCAACC CTGCTGTGGC GCACAGCAGA AGGCCTTTCC 
CACACCCCTA CTGTGAAACA CTTAGAAGCT CTGAGACAGG AGATCAATGC AGCTCGGCCT 
CAGTGCCCTG TAGGCTTCAA CACACTAGCC TTCCCCAGCA TGAAGAGGAA AGATGTTGTA 
GATGAGAAGC AACCATGGGT ATATCTGAAC TGCGGCCATG TTCATGGTTA CCATAACTGG 
GGAAACAAGG AAGAACGTGA CGGCAAAGAT CGTGAATGTC CTATGTGTAG GTCTGTTGGT 
CCCTATGTCC CTCTGTGGCT TGGATGTGAA GCTGGATTTT ATGTGGACGC CGGCCCTCCC 
ACCCATGCCT TTAGCCCCTG TGGGCATGTG TGTTCAGAAA AGACAACGGC TTACTGGTCC 
CAGATCCCGC TTCCTCATGG TACGCACACT TTTCACGCAG CCTGTCCCTT CTGTGCACAT 
CAGTTGGCTG GTGAACAAGG CTATATCAGA CTTATTTTCC AAGGACCTCT AGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017454732.1
CDS	1223..2479
Translation	MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIACTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGVLVMHPRDGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQLQDGSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVVDEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD

Target ORF information:

RefSeq Version	XM_017599243.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pellino E3 ubiquitin protein ligase 1 (Peli1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599243.1

ORF Insert Sequence:

ATGTTTTCTC CTGATCAAGA AAATCATCCT TCCAAAGCCC CAGTAAAATA TGGCGAACTC 
ATTGTCTTAG GGTATAATGG GTCTCTCCCA AACGGCGACA GAGGAAGGAG GAAAAGTAGG 
TTTGCTTTGT TTAAAAGACC TAAGGCAAAT GGGGTGAAGC CTAGCACCGT GCACATTGCA 
TGCACTCCTC AGGCCGCCAA GGCAATAAGC AACAAGGACC AGCATAGCAT ATCGTATACT 
TTATCTCGAG CCCAGACAGT GGTGGTTGAA TATACTCACG ACAGCAACAC TGATATGTTT 
CAGATTGGCC GGTCAACTGA AAGTCCTATT GATTTTGTGG TAACTGACAC AGTTCCTGGA 
AGTCAGAGTA ATTCCGACAC GCAGTCCGTA CAAAGCACTA TATCGAGGTT TGCCTGTAGG 
ATCATTTGTG AACGCAATCC TCCCTTTACA GCTCGGATTT ATGCTGCAGG ATTTGATTCA 
TCAAAAAACA TCTTTCTTGG GGAGAAGGCT GCCAAATGGA AGACGTCCGA CGGGCAGATG 
GACGGCCTGA CCACCAATGG AGTTCTTGTG ATGCATCCAC GCGATGGGTT CACAGAAGAC 
TCCAAGCCTG GAATATGGAG AGAGATATCC GTATGTGGGA ACGTCTTCAG TCTGCGTGAA 
ACCAGATCAG CGCAACAGAG AGGAAAGATG GTGGAAATCG AAACCAATCA GCTGCAAGAT 
GGCTCCTTAA TCGACCTCTG TGGTGCAACC CTGCTGTGGC GCACAGCAGA AGGCCTTTCC 
CACACCCCTA CTGTGAAACA CTTAGAAGCT CTGAGACAGG AGATCAATGC AGCTCGGCCT 
CAGTGCCCTG TAGGCTTCAA CACACTAGCC TTCCCCAGCA TGAAGAGGAA AGATGTTGTA 
GATGAGAAGC AACCATGGGT ATATCTGAAC TGCGGCCATG TTCATGGTTA CCATAACTGG 
GGAAACAAGG AAGAACGTGA CGGCAAAGAT CGTGAATGTC CTATGTGTAG GTCTGTTGGT 
CCCTATGTCC CTCTGTGGCT TGGATGTGAA GCTGGATTTT ATGTGGACGC CGGCCCTCCC 
ACCCATGCCT TTAGCCCCTG TGGGCATGTG TGTTCAGAAA AGACAACGGC TTACTGGTCC 
CAGATCCCGC TTCCTCATGG TACGCACACT TTTCACGCAG CCTGTCCCTT CTGTGCACAT 
CAGTTGGCTG GTGAACAAGG CTATATCAGA CTTATTTTCC AAGGACCTCT AGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Pellino1-mediated TGF-?1 synthesis contributes to mechanical stress induced cardiac fibroblast activation.
Journal of molecular and cellular cardiology79145-56(2015 Feb)
Song J,Zhu Y,Li J,Liu J,Gao Y,Ha T,Que L,Liu L,Zhu G,Chen Q,Xu Y,Li C,Li Y

The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity.
Nature immunology12(10)1002-9(2011 Aug)
Chang M,Jin W,Chang JH,Xiao Y,Brittain GC,Yu J,Zhou X,Wang YH,Cheng X,Li P,Rabinovich BA,Hwu P,Sun SC

Interleukin-1 (IL-1) pathway.
Science signaling3(105)cm1(2010 Jan)
Weber A,Wasiliew P,Kracht M

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production.
Nature immunology10(10)1089-95(2009 Oct)
Chang M,Jin W,Sun SC

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Peli1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報