Cenpc cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cenpc
Entrez Gene ID	305270
Full Name	centromere protein C
Synonyms	Cenpc1
General protein information	Preferred Names centromere protein C Names centromere protein C centromere autoantigen C centromere protein C1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14p21
Summary	centromere autoantigen protein and a component of the inner kinetochore plate; essential for maintanence of kinetochore size and the timely transition to anaphase [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001004098.1	NP_001004098.1	centromere protein C

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CENPC1	XP_001164757.1
Homo sapiens (human)	CENPC	NP_001803.2
Canis lupus familiaris (dog)	CENPC	XP_005628312.1
Rattus norvegicus (Norway rat)	Cenpc	NP_001004098.1
	CENPC1	XP_001099283.2
Bos taurus (cattle)	CENPC1	NP_001039346.2
Mus musculus (house mouse)	Cenpc1	NP_031709.2

Gene Ontology
Bibliography

Related articles in PubMed

Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomes.
Gascoigne KE, Takeuchi K, Suzuki A, Hori T, Fukagawa T, Cheeseman IM
Cell145(3)410-22(2011 Apr)

The C-terminal domain of CENP-C displays multiple and critical functions for mammalian centromere formation.
Trazzi S, Perini G, Bernardoni R, Zoli M, Reese JC, Musacchio A, Della Valle G
PloS one4(6)e5832(2009 Jun)

ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes.
De La Fuente R, Viveiros MM, Wigglesworth K, Eppig JJ
Developmental biology272(1)1-14(2004 Aug)

Adaptive evolution of centromere proteins in plants and animals.
Talbert PB, Bryson TD, Henikoff S
Journal of biology3(4)18(2004)

Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A.
Van Hooser AA, Ouspenski II, Gregson HC, Starr DA, Yen TJ, Goldberg ML, Yokomori K, Earnshaw WC, Sullivan KF, Brinkley BR
Journal of cell science114(Pt 19)3529-42(2001 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cenpc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cenpc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09963	NM_001004098.1 Latest version!	Rattus norvegicus centromere protein C (Cenpc), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cenpc ( NM_001004098.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001004098.1 Rattus norvegicus centromere protein C (Cenpc), mRNA.

Price & Availability↑

CloneID	ORa09963
Clone ID Related Accession (Same CDS sequence)	NM_001004098.1
Accession Version	NM_001004098.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2751bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	centromere protein C
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY693788.1. On Sep 4, 2004 this sequence version replaced XM_223310.2. ##Evidence-Data-START## Transcript exon combination :: AY693788.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCCTCGT TCCATCTGGA TCATCTAAAG AACTACCACA GAAGATTTTG CCGGCCTTCC 
AGAGCACCCA ACATTCCTAC AAAGCAAGGC CAGAACATGC TGGAAATCTT ACAAGATTGT 
TTTGAAGAAC AGAATTCTAC AGAGTCATTG TCTTGTTCAA CACCTAAAGA GAAAGACATT 
TATGTTCAGT CAACAGGCAA AGAGCGCCAA GCATCACATT CAGAATCAGT TCCGATTTCT 
TCAAGGAGGA AGGAAGCTTC TTTGCAAGTT CCTGCAAAAC CAAGTGACCC TGCTGATGAA 
CCAGTTCAGG CTAATGAAGT TCATCAGAAA ATTCTGTCTA CTGATGTGGT CTCCAAAAGT 
ACACCAGACT CAACCAAAAC ATCAAGTAAA GGAGTAAAAG GTCACCATGG TGCGTCTGAT 
GAATTGTACT TACCTGGTGG CTCCCCTGTG GTTCTTCTGG GTGCAAGAGT GTCCGGGTCA 
CAGAAAGCTA TTTCATCTGG TGGCCAAAAA AGAGTGACTT CAAGGCGTTC AGCAGATATG 
CAGTCTTCAA ATACAGACAT TTCTTTTAAA ACCAGGAAAA GGCTAAACTT CGAAGATAAA 
GTTATTTCGA ACACAGCAGA AATAGAGAGC AGTGCATCAC AAGTAGAGGA TAGCATATCC 
GAGGAACAAG AAGGGACATC ATCAGAAACT TCTCAGAAGA GAGACGATCT GAGCTCTGAA 
ATTCAACCAC AATCTAAAAA GAGCTTTTCA GAGTTGTATT TAGAAACTGT CAACAGGAAA 
AGTAAATGCA GTTCTGTTGT TAGGCACACA GCAGCAGTTC CATCTCCTCC GTATCCTCCG 
AATGATATGA AATTATTAGA AGATGAATTT ATTATTGATG GGCCAGATAG AAGCTTTTCA 
AGTCAACCTT GGGTGGTGAT ACCAAGGAAA GGCCACCACA TGCCATTTCC TGAAAACATT 
GCAGTGCCTC AAGGTAAGAA GTCAAGAGAG AAACCTCATC GTCTGTCCGA GAAGACTTTG 
GTAAGTAACA CACAGACTGA TAAGACTGGC CCAGTAGAGG AAGCTCAGCT CTCTGTTGAG 
GAAAAACTGG GAACTACTTT GACAAATGAG TTGGAAAATG ATTGTAGATC TACAGAAAAT 
AAAACGCACT CTGAGAATGC GAAAAAACCA TCTGCACGGA AAAGGACTGT GAAACAGAAG 
CAGAGAAGAC CATCTAAGCC TAACATAGCT CAAGAGCTCA GTATGGGACA GAATGAAACT 
GAAAATAGGA ATATGTCAAA AATTGGCCAA GACAAGTTAC AAATAAATTC AAAAAGAAAT 
ATGGAAGACC ATGAAGAGGT GAGGAACGAG CCTACCCCCA AGAAACCTGT GCCTGCTCTT 
GGAAATAAGA AAGAAAAGGA CAGCACCCAA GCTAATAAGG AAAAATCTAG AAAGAAATGT 
TTTTCTAGAG AGTCCAAGAG GAAATCTGTT CCCAAAGAAG TAACTTTGGC TTCCAGGAGA 
GGTCGTAGAA CTTCTCAGCA TCCGTCTGAG TGGTGGTTGG TAAAACCAAG TGAAGGTTCT 
GTTGATGGAA ATTCTTCAAA GGAGAATGAA TCATCAATTT TATATCCAAA TAGAAAAAAA 
CAGACTAAGA GAAATCACGT ATCTGAGAAT ACTGAGAAGA AACCTGTTCC ATCGAAAAGA 
AAGAAGAAAG AGATCAGCTC AAGAGAACTG AAGTCTTTAA ATGTAAAGGG TTCTGGAGGA 
AATGATGATA TTTCTACTTC CCAGAGGAAG CCGTTGCAAA ACATTGACGC AGATCCAACT 
CAGAAGAGCC TTCATTGTTC TGGACCTACC AGAGGCTCTG AAGATCAAAA CAGTGATATG 
ATATCACAGA ATGTTCATTT AAAGACTCGT AGTGAGCAAC ATAGAAGCAA GACACAAATG 
GAATCTACTT CAAATTCGGA AGTGTGTAAA CATTCAGTGT GGGAAGAAAG TGGACCTTCC 
AGGTTCAAGA ATCTTGAAAT GCCTGGACGC AGTAATTCTG AAGTGGGTGA CGAAAAGGAC 
CAGAAGAGTT TGGATTTGAA AACAAGAAGT TCTAATATGG TACCGAATAG GAATTTACAC 
CACAAATTAG TATTGCCCTC CAACTCACCA AATGTTCGTA GATCTAATAG AATACGTTTG 
AAACCTCTGG AATATTGGCG AGGGGAACGA ATAGATTATC AAGAAAGCTC ATCAGGAAGA 
CTTGTGCTTG AAATAGTGTC CCCAGCTTCA GAATCAGTGA AAAGAAAGGC CAAAAGAAAT 
CTGGACAAAG TCAACAAAGA AACTAACAAG AAACGGATCC ATCTTGATAA CCCTACAAAG 
ACTAAGATAA AGGTGAGTCT GGATATTCCT CTGGGAGATC CCTTCCAGGC AACATTGGCA 
AAGGACCCGG AAACAAGAGA GATTGTCCCC ATGGATCTTA TAAGACCACG AGATACATAC 
CACTTTTTTG TTGAGCAACA TGGTTTGAAA GTTTATAAAA CATTGAATAC AACATTTTTT 
TCTACTGGAA AATTGGTTTT AGGACCCCAT GAAGAAAAAG GAAAACAGCA TGTTGGTCAA 
GATATATTAG TTTTTTATGT TAACTTTGGT GACCTTCTAT GTACATTACA TGAAACACCT 
TATATGCTAA CGACCGGGGA TTCATTCTAT GTTCCTTCAG GTAATCATTA CAACATTAAA 
AACCTCTTGA ATGTGGAAAG TTGTCTTCTT TTTACTCAAA TAAAAAGGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004098.1
CDS	14..2764
Translation	MASFHLDHLKNYHRRFCRPSRAPNIPTKQGQNMLEILQDCFEEQNSTESLSCSTPKEKDIYVQSTGKERQASHSESVPISSRRKEASLQVPAKPSDPADEPVQANEVHQKILSTDVVSKSTPDSTKTSSKGVKGHHGASDELYLPGGSPVVLLGARVSGSQKAISSGGQKRVTSRRSADMQSSNTDISFKTRKRLNFEDKVISNTAEIESSASQVEDSISEEQEGTSSETSQKRDDLSSEIQPQSKKSFSELYLETVNRKSKCSSVVRHTAAVPSPPYPPNDMKLLEDEFIIDGPDRSFSSQPWVVIPRKGHHMPFPENIAVPQGKKSREKPHRLSEKTLVSNTQTDKTGPVEEAQLSVEEKLGTTLTNELENDCRSTENKTHSENAKKPSARKRTVKQKQRRPSKPNIAQELSMGQNETENRNMSKIGQDKLQINSKRNMEDHEEVRNEPTPKKPVPALGNKKEKDSTQANKEKSRKKCFSRESKRKSVPKEVTLASRRGRRTSQHPSEWWLVKPSEGSVDGNSSKENESSILYPNRKKQTKRNHVSENTEKKPVPSKRKKKEISSRELKSLNVKGSGGNDDISTSQRKPLQNIDADPTQKSLHCSGPTRGSEDQNSDMISQNVHLKTRSEQHRSKTQMESTSNSEVCKHSVWEESGPSRFKNLEMPGRSNSEVGDEKDQKSLDLKTRSSNMVPNRNLHHKLVLPSNSPNVRRSNRIRLKPLEYWRGERIDYQESSSGRLVLEIVSPASESVKRKAKRNLDKVNKETNKKRIHLDNPTKTKIKVSLDIPLGDPFQATLAKDPETREIVPMDLIRPRDTYHFFVEQHGLKVYKTLNTTFFSTGKLVLGPHEEKGKQHVGQDILVFYVNFGDLLCTLHETPYMLTTGDSFYVPSGNHYNIKNLLNVESCLLFTQIKR

Target ORF information:

RefSeq Version	NM_001004098.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus centromere protein C (Cenpc), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004098.1

ORF Insert Sequence:

ATGGCCTCGT TCCATCTGGA TCATCTAAAG AACTACCACA GAAGATTTTG CCGGCCTTCC 
AGAGCACCCA ACATTCCTAC AAAGCAAGGC CAGAACATGC TGGAAATCTT ACAAGATTGT 
TTTGAAGAAC AGAATTCTAC AGAGTCATTG TCTTGTTCAA CACCTAAAGA GAAAGACATT 
TATGTTCAGT CAACAGGCAA AGAGCGCCAA GCATCACATT CAGAATCAGT TCCGATTTCT 
TCAAGGAGGA AGGAAGCTTC TTTGCAAGTT CCTGCAAAAC CAAGTGACCC TGCTGATGAA 
CCAGTTCAGG CTAATGAAGT TCATCAGAAA ATTCTGTCTA CTGATGTGGT CTCCAAAAGT 
ACACCAGACT CAACCAAAAC ATCAAGTAAA GGAGTAAAAG GTCACCATGG TGCGTCTGAT 
GAATTGTACT TACCTGGTGG CTCCCCTGTG GTTCTTCTGG GTGCAAGAGT GTCCGGGTCA 
CAGAAAGCTA TTTCATCTGG TGGCCAAAAA AGAGTGACTT CAAGGCGTTC AGCAGATATG 
CAGTCTTCAA ATACAGACAT TTCTTTTAAA ACCAGGAAAA GGCTAAACTT CGAAGATAAA 
GTTATTTCGA ACACAGCAGA AATAGAGAGC AGTGCATCAC AAGTAGAGGA TAGCATATCC 
GAGGAACAAG AAGGGACATC ATCAGAAACT TCTCAGAAGA GAGACGATCT GAGCTCTGAA 
ATTCAACCAC AATCTAAAAA GAGCTTTTCA GAGTTGTATT TAGAAACTGT CAACAGGAAA 
AGTAAATGCA GTTCTGTTGT TAGGCACACA GCAGCAGTTC CATCTCCTCC GTATCCTCCG 
AATGATATGA AATTATTAGA AGATGAATTT ATTATTGATG GGCCAGATAG AAGCTTTTCA 
AGTCAACCTT GGGTGGTGAT ACCAAGGAAA GGCCACCACA TGCCATTTCC TGAAAACATT 
GCAGTGCCTC AAGGTAAGAA GTCAAGAGAG AAACCTCATC GTCTGTCCGA GAAGACTTTG 
GTAAGTAACA CACAGACTGA TAAGACTGGC CCAGTAGAGG AAGCTCAGCT CTCTGTTGAG 
GAAAAACTGG GAACTACTTT GACAAATGAG TTGGAAAATG ATTGTAGATC TACAGAAAAT 
AAAACGCACT CTGAGAATGC GAAAAAACCA TCTGCACGGA AAAGGACTGT GAAACAGAAG 
CAGAGAAGAC CATCTAAGCC TAACATAGCT CAAGAGCTCA GTATGGGACA GAATGAAACT 
GAAAATAGGA ATATGTCAAA AATTGGCCAA GACAAGTTAC AAATAAATTC AAAAAGAAAT 
ATGGAAGACC ATGAAGAGGT GAGGAACGAG CCTACCCCCA AGAAACCTGT GCCTGCTCTT 
GGAAATAAGA AAGAAAAGGA CAGCACCCAA GCTAATAAGG AAAAATCTAG AAAGAAATGT 
TTTTCTAGAG AGTCCAAGAG GAAATCTGTT CCCAAAGAAG TAACTTTGGC TTCCAGGAGA 
GGTCGTAGAA CTTCTCAGCA TCCGTCTGAG TGGTGGTTGG TAAAACCAAG TGAAGGTTCT 
GTTGATGGAA ATTCTTCAAA GGAGAATGAA TCATCAATTT TATATCCAAA TAGAAAAAAA 
CAGACTAAGA GAAATCACGT ATCTGAGAAT ACTGAGAAGA AACCTGTTCC ATCGAAAAGA 
AAGAAGAAAG AGATCAGCTC AAGAGAACTG AAGTCTTTAA ATGTAAAGGG TTCTGGAGGA 
AATGATGATA TTTCTACTTC CCAGAGGAAG CCGTTGCAAA ACATTGACGC AGATCCAACT 
CAGAAGAGCC TTCATTGTTC TGGACCTACC AGAGGCTCTG AAGATCAAAA CAGTGATATG 
ATATCACAGA ATGTTCATTT AAAGACTCGT AGTGAGCAAC ATAGAAGCAA GACACAAATG 
GAATCTACTT CAAATTCGGA AGTGTGTAAA CATTCAGTGT GGGAAGAAAG TGGACCTTCC 
AGGTTCAAGA ATCTTGAAAT GCCTGGACGC AGTAATTCTG AAGTGGGTGA CGAAAAGGAC 
CAGAAGAGTT TGGATTTGAA AACAAGAAGT TCTAATATGG TACCGAATAG GAATTTACAC 
CACAAATTAG TATTGCCCTC CAACTCACCA AATGTTCGTA GATCTAATAG AATACGTTTG 
AAACCTCTGG AATATTGGCG AGGGGAACGA ATAGATTATC AAGAAAGCTC ATCAGGAAGA 
CTTGTGCTTG AAATAGTGTC CCCAGCTTCA GAATCAGTGA AAAGAAAGGC CAAAAGAAAT 
CTGGACAAAG TCAACAAAGA AACTAACAAG AAACGGATCC ATCTTGATAA CCCTACAAAG 
ACTAAGATAA AGGTGAGTCT GGATATTCCT CTGGGAGATC CCTTCCAGGC AACATTGGCA 
AAGGACCCGG AAACAAGAGA GATTGTCCCC ATGGATCTTA TAAGACCACG AGATACATAC 
CACTTTTTTG TTGAGCAACA TGGTTTGAAA GTTTATAAAA CATTGAATAC AACATTTTTT 
TCTACTGGAA AATTGGTTTT AGGACCCCAT GAAGAAAAAG GAAAACAGCA TGTTGGTCAA 
GATATATTAG TTTTTTATGT TAACTTTGGT GACCTTCTAT GTACATTACA TGAAACACCT 
TATATGCTAA CGACCGGGGA TTCATTCTAT GTTCCTTCAG GTAATCATTA CAACATTAAA 
AACCTCTTGA ATGTGGAAAG TTGTCTTCTT TTTACTCAAA TAAAAAGGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomes.
Cell145(3)410-22(2011 Apr)
Gascoigne KE,Takeuchi K,Suzuki A,Hori T,Fukagawa T,Cheeseman IM

The C-terminal domain of CENP-C displays multiple and critical functions for mammalian centromere formation.
PloS one4(6)e5832(2009 Jun)
Trazzi S,Perini G,Bernardoni R,Zoli M,Reese JC,Musacchio A,Della Valle G

ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes.
Developmental biology272(1)1-14(2004 Aug)
De La Fuente R,Viveiros MM,Wigglesworth K,Eppig JJ

Adaptive evolution of centromere proteins in plants and animals.
Journal of biology3(4)18(2004)
Talbert PB,Bryson TD,Henikoff S

Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A.
Journal of cell science114(Pt 19)3529-42(2001 Oct)
Van Hooser AA,Ouspenski II,Gregson HC,Starr DA,Yen TJ,Goldberg ML,Yokomori K,Earnshaw WC,Sullivan KF,Brinkley BR

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Cenpc cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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