Septin11 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Septin11
Entrez Gene ID	305227
Full Name	septin 11
General protein information	Preferred Names septin 11 Names septin-11
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14p22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001107208.2	NP_001100678.1	septin-11

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SEPT11	XP_005639152.1
Bos taurus (cattle)	SEPT11	NP_001075916.1
Drosophila melanogaster (fruit fly)	Sep5	NP_651961.1
Homo sapiens (human)	SEPT11	NP_060713.1
Rattus norvegicus (Norway rat)	Sept11	NP_001100678.1
Gallus gallus (chicken)	SEPT11	XP_004941218.1
Danio rerio (zebrafish)	sept8b	NP_001077035.1
Pan troglodytes (chimpanzee)	SEPT11	XP_517208.3
Mus musculus (house mouse)	Sept11	NP_001009818.1
Xenopus tropicalis (tropical clawed frog)	sept11	NP_001136370.1

Gene Ontology
Bibliography

Related articles in PubMed

Septin 11 is present in GABAergic synapses and plays a functional role in the cytoarchitecture of neurons and GABAergic synaptic connectivity.
Li X, Serwanski DR, Miralles CP, Nagata K, De Blas AL
The Journal of biological chemistry284(25)17253-65(2009 Jun)

Superfluous role of mammalian septins 3 and 5 in neuronal development and synaptic transmission.
Tsang CW, Fedchyshyn M, Harrison J, Xie H, Xue J, Robinson PJ, Wang LY, Trimble WS
Molecular and cellular biology28(23)7012-29(2008 Dec)

SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling.
Sudo K, Ito H, Iwamoto I, Morishita R, Asano T, Nagata K
Human mutation28(10)1005-13(2007 Oct)

Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11.
Nagata K, Asano T, Nozawa Y, Inagaki M
The Journal of biological chemistry279(53)55895-904(2004 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Electron microscopy immunocytochemistry of the cerebellum revealed the accumulation of septin 11 at the neck of dendritic spines, at the bifurcation of dendritic branches, and at some GABAergic synapses.
Title: Septin 11 is present in GABAergic synapses and plays a functional role in the cytoarchitecture of neurons and GABAergic synaptic connectivity.

SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling
Title: SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling.

Sept7/9b/11 form a complex that has effects on filament elongation, bundling, or disruption.
Title: Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11.

The following Septin11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Septin11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11985	NM_001107208.2 Latest version!	Rattus norvegicus septin 11 (Septin11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Septin11 ( NM_001107208.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100678.1 Rattus norvegicus septin 11 (Septin11), mRNA.

Price & Availability↑

CloneID	ORa11985
Clone ID Related Accession (Same CDS sequence)	NM_001107208.2
Accession Version	NM_001107208.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1299bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-12
Organism	Rattus norvegicus(Norway rat)
Product	septin-11
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EU711415.1. On Jun 22, 2008 this sequence version replaced NM_001107208.1. ##Evidence-Data-START## Transcript exon combination :: EU711415.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCCGTGG CGGTGGGGAG ACCGAGTAAT GAAGAACTGC GAAACTTATC ACTTTCTGGC 
CATGTTGGAT TTGACAGTCT CCCTGACCAG CTGGTCAACA AATCCACTTC TCAAGGATTC 
TGTTTCAACA TCCTGTGTGT GGGAGAGACA GGTATTGGCA AATCCACATT GATGGACACT 
TTATTCAACA CCAAATTTGA AAGTGACCCA GCTACTCACA ACGAACCAGG TGTCCGGTTA 
AAAGCCAGAA GTTACGAACT GCAGGAAAGC AACGTACGGC TGAAGCTAAC CATTGTTGAC 
ACAGTGGGAT TTGGAGACCA GATTAATAAA GACGACAGCT ATAAGCCCAT AGTGGAGTAC 
ATTGACGCCC AGTTTGAGGC CTACTTGCAA GAGGAATTGA AAATTAAGCG TTCTCTCTTC 
AACTACCACG ACACGAGGAT TCACGCCTGC CTTTACTTTA TCGCCCCCAC GGGACATTCA 
CTGAAGTCCC TGGACCTGGT CACCATGAAG AAGCTGGACA GCAAGGTGAA CATCATCCCA 
ATCATTGCGA AAGCCGACAC CATCGCCAAG AACGAATTGC ACAAGTTCAA GAGTAAGATC 
ATGAGTGAAC TCGTGAGCAA CGGAGTCCAG ATATATCAGT TCCCCACCGA TGAGGAAACG 
GTGGCCGAGA TTAATGCAAC GATGAGTGTC CATCTCCCAT TTGCAGTGGT TGGCAGTACC 
GAAGAGGTGA AGATTGGCAA CAAGATGGCG AAGGCCAGGC AGTACCCTTG GGGTGTGGTG 
CAGGTTGAGA ACGAAAACCA CTGTGATTTT GTGAAGCTGA GGGAGATGCT GATCCGAGTG 
AACATGGAGG ACCTGCGAGA GCAGACGCAC ACTCGCCACT ACGAGTTGTA TCGGCGCTGT 
AAGCTCGAGG AGATGGGCTT CAAGGACACT GACCCTGACA GCAAGCCCTT CAGTCTCCAG 
GAGACATATG AAGCAAAGAG GAATGAGTTC CTGGGAGAGC TGCAGAAGAA GGAGGAGGAG 
ATGAGACAGA TGTTTGTCAT GAGAGTGAAG GAGAAAGAGG CGGAGCTCAA GGAGGCGGAG 
AAAGAGCTTC ATGAGAAGTT TGACCTCCTG AAGCGGACTC ACCAAGAGGA GAAGAAAAAG 
GTGGAAGACA AGAAGAAGGA GCTTGAGGAG GAGGTGAGCA ACTTCCAGAA GAAGAAGGCG 
GCGGCTCAGC TCTTGCAGTC GCAGGCCCAG CAGTCTGGGG CCCAGCAGAC CAAGAAGGAC 
AAGGATAAGA AAAATAGTCC CTGGCTCTGC ACGGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100678.1
CDS	1..1299
Translation	MAVAVGRPSNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVSNFQKKKAAAQLLQSQAQQSGAQQTKKDKDKKNSPWLCTE

Target ORF information:

RefSeq Version	NM_001107208.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus septin 11 (Septin11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107208.2

ORF Insert Sequence:

ATGGCCGTGG CGGTGGGGAG ACCGAGTAAT GAAGAACTGC GAAACTTATC ACTTTCTGGC 
CATGTTGGAT TTGACAGTCT CCCTGACCAG CTGGTCAACA AATCCACTTC TCAAGGATTC 
TGTTTCAACA TCCTGTGTGT GGGAGAGACA GGTATTGGCA AATCCACATT GATGGACACT 
TTATTCAACA CCAAATTTGA AAGTGACCCA GCTACTCACA ACGAACCAGG TGTCCGGTTA 
AAAGCCAGAA GTTACGAACT GCAGGAAAGC AACGTACGGC TGAAGCTAAC CATTGTTGAC 
ACAGTGGGAT TTGGAGACCA GATTAATAAA GACGACAGCT ATAAGCCCAT AGTGGAGTAC 
ATTGACGCCC AGTTTGAGGC CTACTTGCAA GAGGAATTGA AAATTAAGCG TTCTCTCTTC 
AACTACCACG ACACGAGGAT TCACGCCTGC CTTTACTTTA TCGCCCCCAC GGGACATTCA 
CTGAAGTCCC TGGACCTGGT CACCATGAAG AAGCTGGACA GCAAGGTGAA CATCATCCCA 
ATCATTGCGA AAGCCGACAC CATCGCCAAG AACGAATTGC ACAAGTTCAA GAGTAAGATC 
ATGAGTGAAC TCGTGAGCAA CGGAGTCCAG ATATATCAGT TCCCCACCGA TGAGGAAACG 
GTGGCCGAGA TTAATGCAAC GATGAGTGTC CATCTCCCAT TTGCAGTGGT TGGCAGTACC 
GAAGAGGTGA AGATTGGCAA CAAGATGGCG AAGGCCAGGC AGTACCCTTG GGGTGTGGTG 
CAGGTTGAGA ACGAAAACCA CTGTGATTTT GTGAAGCTGA GGGAGATGCT GATCCGAGTG 
AACATGGAGG ACCTGCGAGA GCAGACGCAC ACTCGCCACT ACGAGTTGTA TCGGCGCTGT 
AAGCTCGAGG AGATGGGCTT CAAGGACACT GACCCTGACA GCAAGCCCTT CAGTCTCCAG 
GAGACATATG AAGCAAAGAG GAATGAGTTC CTGGGAGAGC TGCAGAAGAA GGAGGAGGAG 
ATGAGACAGA TGTTTGTCAT GAGAGTGAAG GAGAAAGAGG CGGAGCTCAA GGAGGCGGAG 
AAAGAGCTTC ATGAGAAGTT TGACCTCCTG AAGCGGACTC ACCAAGAGGA GAAGAAAAAG 
GTGGAAGACA AGAAGAAGGA GCTTGAGGAG GAGGTGAGCA ACTTCCAGAA GAAGAAGGCG 
GCGGCTCAGC TCTTGCAGTC GCAGGCCCAG CAGTCTGGGG CCCAGCAGAC CAAGAAGGAC 
AAGGATAAGA AAAATAGTCC CTGGCTCTGC ACGGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Septin 11 is present in GABAergic synapses and plays a functional role in the cytoarchitecture of neurons and GABAergic synaptic connectivity.
The Journal of biological chemistry284(25)17253-65(2009 Jun)
Li X,Serwanski DR,Miralles CP,Nagata K,De Blas AL

Superfluous role of mammalian septins 3 and 5 in neuronal development and synaptic transmission.
Molecular and cellular biology28(23)7012-29(2008 Dec)
Tsang CW,Fedchyshyn M,Harrison J,Xie H,Xue J,Robinson PJ,Wang LY,Trimble WS

SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling.
Human mutation28(10)1005-13(2007 Oct)
Sudo K,Ito H,Iwamoto I,Morishita R,Asano T,Nagata K

Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11.
The Journal of biological chemistry279(53)55895-904(2004 Dec)
Nagata K,Asano T,Nozawa Y,Inagaki M

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Septin11 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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