Bfar cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Bfar
Entrez Gene ID	304709
Full Name	bifunctional apoptosis regulator
Synonyms	RGD1305537
General protein information	Preferred Names bifunctional apoptosis regulator Names bifunctional apoptosis regulator
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001013125.2	NP_001013143.1	bifunctional apoptosis regulator

Pathways from BioSystems

Homologies

Bos taurus (cattle)	BFAR	NP_001092339.1
Homo sapiens (human)	BFAR	NP_057645.1
Pan troglodytes (chimpanzee)	BFAR	XP_001148011.1
	BFAR	XP_001107948.1
Canis lupus familiaris (dog)	BFAR	XP_005621580.1
Mus musculus (house mouse)	Bfar	NP_080252.1
Rattus norvegicus (Norway rat)	Bfar	NP_001013143.1
Gallus gallus (chicken)	BFAR	XP_414737.2
Xenopus tropicalis (tropical clawed frog)	bfar	NP_001016975.1

Gene Ontology
Bibliography

Related articles in PubMed

Bifunctional apoptosis regulator (BAR), an endoplasmic reticulum (ER)-associated E3 ubiquitin ligase, modulates BI-1 protein stability and function in ER Stress.
Rong J, Chen L, Toth JI, Tcherpakov M, Petroski MD, Reed JC
The Journal of biological chemistry286(2)1453-63(2011 Jan)

Gene and alternative splicing annotation with AIR.
Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G
Genome research15(1)54-66(2005 Jan)

BAR: An apoptosis regulator at the intersection of caspases and Bcl-2 family proteins.
Zhang H, Xu Q, Krajewski S, Krajewska M, Xie Z, Fuess S, Kitada S, Pawlowski K, Godzik A, Reed JC
Proceedings of the National Academy of Sciences of the United States of America97(6)2597-602(2000 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Bfar gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bfar cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03464	NM_001013125.2 Latest version!	Rattus norvegicus bifunctional apoptosis regulator (Bfar), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Bfar ( NM_001013125.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001013143.1 Rattus norvegicus bifunctional apoptosis regulator (Bfar), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa03464
Clone ID Related Accession (Same CDS sequence)	NM_001013125.2
Accession Version	NM_001013125.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1353bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Rattus norvegicus(Norway rat)
Product	bifunctional apoptosis regulator
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07028979.1, FM033098.1 and BC087103.1. On Aug 10, 2016 this sequence version replaced NM_001013125.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the protein. ##Evidence-Data-START## Transcript exon combination :: BC087103.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGC CTCAGAAAAA TGACCTGAGC ATGAGAGGGC AGGAAGAAGA TCATCCTGTC 
AGAAGCAGTG GCCCTCAGAT TTCTGTGAGT GAGTTCTCCT GCCACTGCTG TTACGACACC 
CTGGTTAACC CCACCACCTT GAACTGTGGC CACAGCTTCT GCCGGCACTG CTTAGCATTA 
TGGTGGATGT CTTCAAAGAA AACAGAGTGT CCAGAATGCA GAGAAAAATG GGAAGGTTTT 
CCCAAAGTCA ACATTCTCCT CAGGGACGCC ATTGAAAAGT TATTTCCTGA TGCCATTAAA 
ATGCGAGTTG AAGACATTCA GCAGAATAAT GATGTAGTCC AAAGTCTTGC AGCCTTTCAG 
AAATATGGGA ATGATCAAAA TCCCTTAGCT CCCAGCACAG GGAGAGTGAA TCAGCAGAGA 
GGAGGGGGAT TCTTCTCCGG CGTACTCACA GCTTTAACTG GTGTGGCAGT CATCCTGCTT 
GTGTATCACT GGCGCAGCAG AGAGTCTGAG CATGGCCTCC TGGTGCACAA GGCTGTAGAC 
AAATGGACGA CAGAAGAAGT TGTCCTCTGG TTAGAACAGC TAGGCCCTTG GGCCTCACTG 
TACAGAGACA GGTTCTTATC TGAAAGAGTA AATGGAAGGT TACTTTTAAC TTTGACAGAA 
GAAGAATTTT CCAGGGCACC TTACACCATA GAAAACAGTA GCCACAGAAG AGTCATCCTC 
ATGGAGCTGG AGCGCGTGAG AGCCCTGGGT GTGAAGCCAC CACAGAATCT CTGGGAATAC 
AAGGCTGTCA ACCCAGGCAG GTCCCTGTTC TTGCTCTACG CCCTCAAGAG CTCACCAAGA 
CTTGGCTTGC TATACCTGTA CTTGTTTGAC TACACAGACT CCTTTCTACC CTTCATCCAC 
ACCATCTGCC CTTTGCAGGA AGACAGCTTT GGCGAGGACA TCTTCACCAA GCTTCTGGAC 
CTGAGGGAGC CCACGTGGAA GCAGTGGAGA GAATTCCTTA TCAAGTACTC CTTTCTCCCG 
TATCAGCTGA TTGCAGAGTT TGCCTGGGAC TGGCTGGAGG TCCACTACTG GACATCGCGC 
TTCCTCATCG TCAATGCCAT GCTGCTGTCT GTTCTGGAGT TGTTCTCTTT TTGGAGGATC 
TGGTCAAGAA GCGAACTGAA GACAGTGCCC CAGAGGATGT GGAGCCACTT TTGGAAAGTA 
TCGACGCAGG GGCTTTTCAT GGCCATGTTC TGGCCGCTCA TTCCTCAGTT TGTCTGCAAC 
TGTTTATTTT ACTGGGCTCT GTACTTCAAC CCAATTATTA ACATTGATCT GGTGGTCAAG 
GAAATCCGAC GGCTGGAAAC CCAAGTGTTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013143.1
CDS	165..1517
Translation	MEEPQKNDLSMRGQEEDHPVRSSGPQISVSEFSCHCCYDTLVNPTTLNCGHSFCRHCLALWWMSSKKTECPECREKWEGFPKVNILLRDAIEKLFPDAIKMRVEDIQQNNDVVQSLAAFQKYGNDQNPLAPSTGRVNQQRGGGFFSGVLTALTGVAVILLVYHWRSRESEHGLLVHKAVDKWTTEEVVLWLEQLGPWASLYRDRFLSERVNGRLLLTLTEEEFSRAPYTIENSSHRRVILMELERVRALGVKPPQNLWEYKAVNPGRSLFLLYALKSSPRLGLLYLYLFDYTDSFLPFIHTICPLQEDSFGEDIFTKLLDLREPTWKQWREFLIKYSFLPYQLIAEFAWDWLEVHYWTSRFLIVNAMLLSVLELFSFWRIWSRSELKTVPQRMWSHFWKVSTQGLFMAMFWPLIPQFVCNCLFYWALYFNPIINIDLVVKEIRRLETQVF

Target ORF information:

RefSeq Version	NM_001013125.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus bifunctional apoptosis regulator (Bfar), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013125.2

ORF Insert Sequence:

ATGGAGGAGC CTCAGAAAAA TGACCTGAGC ATGAGAGGGC AGGAAGAAGA TCATCCTGTC 
AGAAGCAGTG GCCCTCAGAT TTCTGTGAGT GAGTTCTCCT GCCACTGCTG TTACGACACC 
CTGGTTAACC CCACCACCTT GAACTGTGGC CACAGCTTCT GCCGGCACTG CTTAGCATTA 
TGGTGGATGT CTTCAAAGAA AACAGAGTGT CCAGAATGCA GAGAAAAATG GGAAGGTTTT 
CCCAAAGTCA ACATTCTCCT CAGGGACGCC ATTGAAAAGT TATTTCCTGA TGCCATTAAA 
ATGCGAGTTG AAGACATTCA GCAGAATAAT GATGTAGTCC AAAGTCTTGC AGCCTTTCAG 
AAATATGGGA ATGATCAAAA TCCCTTAGCT CCCAGCACAG GGAGAGTGAA TCAGCAGAGA 
GGAGGGGGAT TCTTCTCCGG CGTACTCACA GCTTTAACTG GTGTGGCAGT CATCCTGCTT 
GTGTATCACT GGCGCAGCAG AGAGTCTGAG CATGGCCTCC TGGTGCACAA GGCTGTAGAC 
AAATGGACGA CAGAAGAAGT TGTCCTCTGG TTAGAACAGC TAGGCCCTTG GGCCTCACTG 
TACAGAGACA GGTTCTTATC TGAAAGAGTA AATGGAAGGT TACTTTTAAC TTTGACAGAA 
GAAGAATTTT CCAGGGCACC TTACACCATA GAAAACAGTA GCCACAGAAG AGTCATCCTC 
ATGGAGCTGG AGCGCGTGAG AGCCCTGGGT GTGAAGCCAC CACAGAATCT CTGGGAATAC 
AAGGCTGTCA ACCCAGGCAG GTCCCTGTTC TTGCTCTACG CCCTCAAGAG CTCACCAAGA 
CTTGGCTTGC TATACCTGTA CTTGTTTGAC TACACAGACT CCTTTCTACC CTTCATCCAC 
ACCATCTGCC CTTTGCAGGA AGACAGCTTT GGCGAGGACA TCTTCACCAA GCTTCTGGAC 
CTGAGGGAGC CCACGTGGAA GCAGTGGAGA GAATTCCTTA TCAAGTACTC CTTTCTCCCG 
TATCAGCTGA TTGCAGAGTT TGCCTGGGAC TGGCTGGAGG TCCACTACTG GACATCGCGC 
TTCCTCATCG TCAATGCCAT GCTGCTGTCT GTTCTGGAGT TGTTCTCTTT TTGGAGGATC 
TGGTCAAGAA GCGAACTGAA GACAGTGCCC CAGAGGATGT GGAGCCACTT TTGGAAAGTA 
TCGACGCAGG GGCTTTTCAT GGCCATGTTC TGGCCGCTCA TTCCTCAGTT TGTCTGCAAC 
TGTTTATTTT ACTGGGCTCT GTACTTCAAC CCAATTATTA ACATTGATCT GGTGGTCAAG 
GAAATCCGAC GGCTGGAAAC CCAAGTGTTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Bifunctional apoptosis regulator (BAR), an endoplasmic reticulum (ER)-associated E3 ubiquitin ligase, modulates BI-1 protein stability and function in ER Stress.
The Journal of biological chemistry286(2)1453-63(2011 Jan)
Rong J,Chen L,Toth JI,Tcherpakov M,Petroski MD,Reed JC

Gene and alternative splicing annotation with AIR.
Genome research15(1)54-66(2005 Jan)
Florea L,Di Francesco V,Miller J,Turner R,Yao A,Harris M,Walenz B,Mobarry C,Merkulov GV,Charlab R,Dew I,Deng Z,Istrail S,Li P,Sutton G

BAR: An apoptosis regulator at the intersection of caspases and Bcl-2 family proteins.
Proceedings of the National Academy of Sciences of the United States of America97(6)2597-602(2000 Mar)
Zhang H,Xu Q,Krajewski S,Krajewska M,Xie Z,Fuess S,Kitada S,Pawlowski K,Godzik A,Reed JC

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Bfar cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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