Fscn2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fscn2
Entrez Gene ID	303741
Full Name	fascin actin-bundling protein 2, retinal
General protein information	Preferred Names fascin actin-bundling protein 2, retinal Names fascin-2 fascin homolog 2, actin-bundling protein, retinal
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q32.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001107072.1	NP_001100542.1	fascin-2
XM_008768476.2	XP_008766698.1	fascin-2 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	FSCN2	XP_003435223.1
Rattus norvegicus (Norway rat)	Fscn2	NP_001100542.1
Drosophila melanogaster (fruit fly)	sn	NP_001162696.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012991	XP_003437121.1
Pan troglodytes (chimpanzee)	FSCN2	XP_003953273.1
Gallus gallus (chicken)	FSCN2	NP_001171209.1
Danio rerio (zebrafish)	fscn2a	NP_001116988.1
Homo sapiens (human)	FSCN2	NP_001070650.1
	FSCN2	XP_001110926.2
Mus musculus (house mouse)	Fscn2	NP_766390.2
Danio rerio (zebrafish)	fscn2b	NP_957064.2
Xenopus tropicalis (tropical clawed frog)	fscn2	NP_001093724.1
Bos taurus (cattle)	FSCN2	NP_788806.1

Gene Ontology
Bibliography

Related articles in PubMed

Fascin2 regulates cisplatin-induced apoptosis in NRK-52E cells.
Wang X, Nichols L, Grunz-Borgmann EA, Sun Z, Meininger GA, Domeier TL, Baines CP, Parrish AR
Toxicology letters26656-64(2017 Jan)

HCN1 and HCN2 proteins are expressed in cochlear hair cells: HCN1 can form a ternary complex with protocadherin 15 CD3 and F-actin-binding filamin A or can interact with HCN2.
Ramakrishnan NA, Drescher MJ, Khan KM, Hatfield JS, Drescher DG
The Journal of biological chemistry287(45)37628-46(2012 Nov)

The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice.
Shin JB, Longo-Guess CM, Gagnon LH, Saylor KW, Dumont RA, Spinelli KJ, Pagana JM, Wilmarth PA, David LL, Gillespie PG, Johnson KR
The Journal of neuroscience : the official journal of the Society for Neuroscience30(29)9683-94(2010 Jul)

Targeted disruption of FSCN2 gene induces retinopathy in mice.
Yokokura S, Wada Y, Nakai S, Sato H, Yao R, Yamanaka H, Ito S, Sagara Y, Takahashi M, Nakamura Y, Tamai M, Noda T
Investigative ophthalmology & visual science46(8)2905-15(2005 Aug)

Mutation of human retinal fascin gene (FSCN2) causes autosomal dominant retinitis pigmentosa.
Wada Y, Abe T, Takeshita T, Sato H, Yanashima K, Tamai M
Investigative ophthalmology & visual science42(10)2395-400(2001 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These data demonstrate that fascin2, a putative target of alpha(E)-catenin, may play important role in preventing cisplatin-induced acute kidney injury.
Title: Fascin2 regulates cisplatin-induced apoptosis in NRK-52E cells.

The following Fscn2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fscn2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13736	NM_001107072.1 Latest version!	Rattus norvegicus fascin actin-bundling protein 2, retinal (Fscn2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa46069	XM_008768476.2 Latest version!	Rattus norvegicus fascin actin-bundling protein 2, retinal (Fscn2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fscn2 ( NM_001107072.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100542.1 Rattus norvegicus fascin actin-bundling protein 2, retinal (Fscn2), mRNA.

Price & Availability↑

CloneID	ORa13736
Clone ID Related Accession (Same CDS sequence)	NM_001107072.1
Accession Version	NM_001107072.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	fascin-2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473948.1. On or before Oct 4, 2007 this sequence version replaced XM_221196.3, XM_001081803.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCCAACCA ACGGCTTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTTGT GAACGATGCC 
GACCGCTACC TCACGGCTGA GAGCTTTGGC TTCAAGGTCA ACGCTTCCGC AGCCAGCCTC 
AAGAGGAAGC AGATATGGGT CCTGGAGCCT GACCCAGGGC AGGGCACTGC TGTGCTGTTT 
CGCAGCAGCC ACCTAGGCCG CTACCTGTCG GCAGAAGAAG ATGGGCGCGT GGCCTGTGAG 
ATGGATCACC CGGGCCGTGA CTGTCGCTTC TTGGTCTTGC CGCAGCCTGA CGGGCGCTGG 
GTGCTGCAGT CAGAGCCACA CGGCCGCTTC TTTGGTGGCG TTGAGGACCG ACTGTCCTGC 
TTTGCTACGG CCATCTCCCC GGCAGAGCTG TGGACCGTAC ACCTGGCCAT CCACCCACAG 
GCTCACTTGC TGAGTGTGAG CCGCCGGCGC TACGTGCACC TGTGCCTTCA GGAGGACGAG 
ATGGCGGCAG ATGGTGACAT GCCGTGGGGT GTGGACGCAC TGCTCACCCT CATTTTCCAG 
AGCAGGCGGT ACTGCCTCAA GTCTTATGAC AGCCGCTACC TTCGAAGTGA TGGCCGCCTT 
GTCTGGGAGC CTGAAGCCCA TGCCTGCTAC ACACTGGAGT TCAAGGCAGG CAAGCTGGCC 
TTCAAGGACT GTGACGGCCG ATACCTGGCA CCTGTGGGGC CTGCCGGCAC GCTTAAGGCT 
GGCCGAAACA CGAGGCCCGG CAAGGATGAA CTCTTCGACC TGGAGCAGAG TCACCCACAG 
GTGGTACTGG TAGCTGCCAA CCACCGCTAC GTCTCTGTGA GGCAAGGAAT CAATGTCTCA 
GCCAATCAGG ATGAAGAACT GGACCATGAG ACATTCCTAA TGCAAATCGA CCAGGAGACA 
AAGAAGTGTA CTTTCTATTC CAGCACTGGG GGCTACTGGA CCTTGGTCAC TCACGGGGGC 
ATTCAGGCCA CAGCCACGCA AGTTTCTGCC AACACCATGT TTGAAATAGA ATGGCACGGC 
CGGCGGGTGG CACTTAAAGC CAGCAATGGG CGTTATGTGT GCATGAAGAA GAATGGGCAG 
CTGGCTGCTA TCAGTGACTT TGTGGGTGAG GACGAGTTAT TCATCCTCAA ACTCATCAAC 
CGACCCATCC TGGTGCTCCG TGGCCTGGAT GGCTTTGTGT GCCACCGCCG AGGCTCCAAC 
CAGCTGGACA CCAACCGCTC CACCTACGAT GTCTTCCACC TGAGCTTCAG GGATGGCGCC 
TATCAAATCA GAGGCCGTGG AGGTGGGTTC TGGTACACTG GGAGCCATGG AAGTGTGTGC 
AGCGATGGTG ACTTGGCGGA GGATTTCCTC TTCGAGTTCC GAGAGCGTGG CCGTTTGGCC 
ATCCGTGCCC TCAGTGGCAA GTACCTGCGT GGAGGTGCCT CAGGGCTGCT GCGTGCTGAC 
GCGGACCTGC CTACGGGGGA AGCTCTCTGG GAATATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100542.1
CDS	169..1647
Translation	MPTNGLHQVLKIQFGLVNDADRYLTAESFGFKVNASAASLKRKQIWVLEPDPGQGTAVLFRSSHLGRYLSAEEDGRVACEMDHPGRDCRFLVLPQPDGRWVLQSEPHGRFFGGVEDRLSCFATAISPAELWTVHLAIHPQAHLLSVSRRRYVHLCLQEDEMAADGDMPWGVDALLTLIFQSRRYCLKSYDSRYLRSDGRLVWEPEAHACYTLEFKAGKLAFKDCDGRYLAPVGPAGTLKAGRNTRPGKDELFDLEQSHPQVVLVAANHRYVSVRQGINVSANQDEELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIQATATQVSANTMFEIEWHGRRVALKASNGRYVCMKKNGQLAAISDFVGEDELFILKLINRPILVLRGLDGFVCHRRGSNQLDTNRSTYDVFHLSFRDGAYQIRGRGGGFWYTGSHGSVCSDGDLAEDFLFEFRERGRLAIRALSGKYLRGGASGLLRADADLPTGEALWEY

Target ORF information:

RefSeq Version	NM_001107072.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus fascin actin-bundling protein 2, retinal (Fscn2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107072.1

ORF Insert Sequence:

ATGCCAACCA ACGGCTTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTTGT GAACGATGCC 
GACCGCTACC TCACGGCTGA GAGCTTTGGC TTCAAGGTCA ACGCTTCCGC AGCCAGCCTC 
AAGAGGAAGC AGATATGGGT CCTGGAGCCT GACCCAGGGC AGGGCACTGC TGTGCTGTTT 
CGCAGCAGCC ACCTAGGCCG CTACCTGTCG GCAGAAGAAG ATGGGCGCGT GGCCTGTGAG 
ATGGATCACC CGGGCCGTGA CTGTCGCTTC TTGGTCTTGC CGCAGCCTGA CGGGCGCTGG 
GTGCTGCAGT CAGAGCCACA CGGCCGCTTC TTTGGTGGCG TTGAGGACCG ACTGTCCTGC 
TTTGCTACGG CCATCTCCCC GGCAGAGCTG TGGACCGTAC ACCTGGCCAT CCACCCACAG 
GCTCACTTGC TGAGTGTGAG CCGCCGGCGC TACGTGCACC TGTGCCTTCA GGAGGACGAG 
ATGGCGGCAG ATGGTGACAT GCCGTGGGGT GTGGACGCAC TGCTCACCCT CATTTTCCAG 
AGCAGGCGGT ACTGCCTCAA GTCTTATGAC AGCCGCTACC TTCGAAGTGA TGGCCGCCTT 
GTCTGGGAGC CTGAAGCCCA TGCCTGCTAC ACACTGGAGT TCAAGGCAGG CAAGCTGGCC 
TTCAAGGACT GTGACGGCCG ATACCTGGCA CCTGTGGGGC CTGCCGGCAC GCTTAAGGCT 
GGCCGAAACA CGAGGCCCGG CAAGGATGAA CTCTTCGACC TGGAGCAGAG TCACCCACAG 
GTGGTACTGG TAGCTGCCAA CCACCGCTAC GTCTCTGTGA GGCAAGGAAT CAATGTCTCA 
GCCAATCAGG ATGAAGAACT GGACCATGAG ACATTCCTAA TGCAAATCGA CCAGGAGACA 
AAGAAGTGTA CTTTCTATTC CAGCACTGGG GGCTACTGGA CCTTGGTCAC TCACGGGGGC 
ATTCAGGCCA CAGCCACGCA AGTTTCTGCC AACACCATGT TTGAAATAGA ATGGCACGGC 
CGGCGGGTGG CACTTAAAGC CAGCAATGGG CGTTATGTGT GCATGAAGAA GAATGGGCAG 
CTGGCTGCTA TCAGTGACTT TGTGGGTGAG GACGAGTTAT TCATCCTCAA ACTCATCAAC 
CGACCCATCC TGGTGCTCCG TGGCCTGGAT GGCTTTGTGT GCCACCGCCG AGGCTCCAAC 
CAGCTGGACA CCAACCGCTC CACCTACGAT GTCTTCCACC TGAGCTTCAG GGATGGCGCC 
TATCAAATCA GAGGCCGTGG AGGTGGGTTC TGGTACACTG GGAGCCATGG AAGTGTGTGC 
AGCGATGGTG ACTTGGCGGA GGATTTCCTC TTCGAGTTCC GAGAGCGTGG CCGTTTGGCC 
ATCCGTGCCC TCAGTGGCAA GTACCTGCGT GGAGGTGCCT CAGGGCTGCT GCGTGCTGAC 
GCGGACCTGC CTACGGGGGA AGCTCTCTGG GAATATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fscn2 ( XM_008768476.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008766698.1 Rattus norvegicus fascin actin-bundling protein 2, retinal (Fscn2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa46069
Clone ID Related Accession (Same CDS sequence)	XM_008768476.2
Accession Version	XM_008768476.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1548bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	fascin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008768476.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAACCA ACGGCTTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTTGT GAACGATGCC 
GACCGCTACC TCACGGCTGA GAGCTTTGGC TTCAAGGTCA ACGCTTCCGC AGCCAGCCTC 
AAGAGGAAGC AGATATGGGT CCTGGAGCCT GACCCAGGGC AGGGCACTGC TGTGCTGTTT 
CGCAGCAGCC ACCTAGGCCG CTACCTGTCG GCAGAAGAAG ATGGGCGCGT GGCCTGTGAG 
ATGGATCACC CGGGCCGTGA CTGTCGCTTC TTGGTCTTGC CGCAGCCTGA CGGGCGCTGG 
GTGCTGCAGT CAGAGCCACA CGGCCGCTTC TTTGGTGGCG TTGAGGACCG ACTGTCCTGC 
TTTGCTACGG CCATCTCCCC GGCAGAGCTG TGGACCGTAC ACCTGGCCAT CCACCCACAG 
GCTCACTTGC TGAGTGTGAG CCGCCGGCGC TACGTGCACC TGTGCCTTCA GGAGGACGAG 
ATGGCGGCAG ATGGTGACAT GCCGTGGGGT GTGGACGCAC TGCTCACCCT CATTTTCCAG 
AGCAGGCGGT ACTGCCTCAA GTCTTATGAC AGCCGCTACC TTCGAAGTGA TGGCCGCCTT 
GTCTGGGAGC CTGAAGCCCA TGCCTGCTAC ACACTGGAGT TCAAGGCAGG CAAGCTGGCC 
TTCAAGGACT GTGACGGCCG ATACCTGGCA CCTGTGGGGC CTGCCGGCAC GCTTAAGGCT 
GGCCGAAACA CGAGGCCCGG CAAGGATGAA CTCTTCGACC TGGAGCAGAG TCACCCACAG 
GTGGTACTGG TAGCTGCCAA CCACCGCTAC GTCTCTGTGA GGCAAGGAAT CAATGTCTCA 
GCCAATCAGG ATGAAGAACT GGACCATGAG ACATTCCTAA TGCAAATCGA CCAGGAGACA 
AAGAAGTGTA CTTTCTATTC CAGCACTGGG GGCTACTGGA CCTTGGTCAC TCACGGGGGC 
ATTCAGGCCA CAGCCACGCA AGTTTCTGCC AACACCATGT TTGAAATAGA ATGGCACGGC 
CGGCGGGTGG CACTTAAAGC CAGCAATGGG CGTTATGTGT GCATGAAGAA GAATGGGCAG 
CTGGCTGCTA TCAGTGACTT TGTGGGTGAG CATTCCCTGC CCTCTTGGAC AGGTAGGGAC 
AGGAGTGGTC AGTCCACAGC ACCCTCTCCT ACAGGTGAGG ACGAGTTATT CATCCTCAAA 
CTCATCAACC GACCCATCCT GGTGCTCCGT GGCCTGGATG GCTTTGTGTG CCACCGCCGA 
GGCTCCAACC AGCTGGACAC CAACCGCTCC ACCTACGATG TCTTCCACCT GAGCTTCAGG 
GATGGCGCCT ATCAAATCAG AGGCCGTGGA GGTGGGTTCT GGTACACTGG GAGCCATGGA 
AGTGTGTGCA GCGATGGTGA CTTGGCGGAG GATTTCCTCT TCGAGTTCCG AGAGCGTGGC 
CGTTTGGCCA TCCGTGCCCT CAGTGGCAAG TACCTGCGTG GAGGTGCCTC AGGGCTGCTG 
CGTGCTGACG CGGACCTGCC TACGGGGGAA GCTCTCTGGG AATATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008766698.1
CDS	5349..6896
Translation	MPTNGLHQVLKIQFGLVNDADRYLTAESFGFKVNASAASLKRKQIWVLEPDPGQGTAVLFRSSHLGRYLSAEEDGRVACEMDHPGRDCRFLVLPQPDGRWVLQSEPHGRFFGGVEDRLSCFATAISPAELWTVHLAIHPQAHLLSVSRRRYVHLCLQEDEMAADGDMPWGVDALLTLIFQSRRYCLKSYDSRYLRSDGRLVWEPEAHACYTLEFKAGKLAFKDCDGRYLAPVGPAGTLKAGRNTRPGKDELFDLEQSHPQVVLVAANHRYVSVRQGINVSANQDEELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIQATATQVSANTMFEIEWHGRRVALKASNGRYVCMKKNGQLAAISDFVGEHSLPSWTGRDRSGQSTAPSPTGEDELFILKLINRPILVLRGLDGFVCHRRGSNQLDTNRSTYDVFHLSFRDGAYQIRGRGGGFWYTGSHGSVCSDGDLAEDFLFEFRERGRLAIRALSGKYLRGGASGLLRADADLPTGEALWEY

Target ORF information:

RefSeq Version	XM_008768476.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus fascin actin-bundling protein 2, retinal (Fscn2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008768476.2

ORF Insert Sequence:

ATGCCAACCA ACGGCTTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTTGT GAACGATGCC 
GACCGCTACC TCACGGCTGA GAGCTTTGGC TTCAAGGTCA ACGCTTCCGC AGCCAGCCTC 
AAGAGGAAGC AGATATGGGT CCTGGAGCCT GACCCAGGGC AGGGCACTGC TGTGCTGTTT 
CGCAGCAGCC ACCTAGGCCG CTACCTGTCG GCAGAAGAAG ATGGGCGCGT GGCCTGTGAG 
ATGGATCACC CGGGCCGTGA CTGTCGCTTC TTGGTCTTGC CGCAGCCTGA CGGGCGCTGG 
GTGCTGCAGT CAGAGCCACA CGGCCGCTTC TTTGGTGGCG TTGAGGACCG ACTGTCCTGC 
TTTGCTACGG CCATCTCCCC GGCAGAGCTG TGGACCGTAC ACCTGGCCAT CCACCCACAG 
GCTCACTTGC TGAGTGTGAG CCGCCGGCGC TACGTGCACC TGTGCCTTCA GGAGGACGAG 
ATGGCGGCAG ATGGTGACAT GCCGTGGGGT GTGGACGCAC TGCTCACCCT CATTTTCCAG 
AGCAGGCGGT ACTGCCTCAA GTCTTATGAC AGCCGCTACC TTCGAAGTGA TGGCCGCCTT 
GTCTGGGAGC CTGAAGCCCA TGCCTGCTAC ACACTGGAGT TCAAGGCAGG CAAGCTGGCC 
TTCAAGGACT GTGACGGCCG ATACCTGGCA CCTGTGGGGC CTGCCGGCAC GCTTAAGGCT 
GGCCGAAACA CGAGGCCCGG CAAGGATGAA CTCTTCGACC TGGAGCAGAG TCACCCACAG 
GTGGTACTGG TAGCTGCCAA CCACCGCTAC GTCTCTGTGA GGCAAGGAAT CAATGTCTCA 
GCCAATCAGG ATGAAGAACT GGACCATGAG ACATTCCTAA TGCAAATCGA CCAGGAGACA 
AAGAAGTGTA CTTTCTATTC CAGCACTGGG GGCTACTGGA CCTTGGTCAC TCACGGGGGC 
ATTCAGGCCA CAGCCACGCA AGTTTCTGCC AACACCATGT TTGAAATAGA ATGGCACGGC 
CGGCGGGTGG CACTTAAAGC CAGCAATGGG CGTTATGTGT GCATGAAGAA GAATGGGCAG 
CTGGCTGCTA TCAGTGACTT TGTGGGTGAG CATTCCCTGC CCTCTTGGAC AGGTAGGGAC 
AGGAGTGGTC AGTCCACAGC ACCCTCTCCT ACAGGTGAGG ACGAGTTATT CATCCTCAAA 
CTCATCAACC GACCCATCCT GGTGCTCCGT GGCCTGGATG GCTTTGTGTG CCACCGCCGA 
GGCTCCAACC AGCTGGACAC CAACCGCTCC ACCTACGATG TCTTCCACCT GAGCTTCAGG 
GATGGCGCCT ATCAAATCAG AGGCCGTGGA GGTGGGTTCT GGTACACTGG GAGCCATGGA 
AGTGTGTGCA GCGATGGTGA CTTGGCGGAG GATTTCCTCT TCGAGTTCCG AGAGCGTGGC 
CGTTTGGCCA TCCGTGCCCT CAGTGGCAAG TACCTGCGTG GAGGTGCCTC AGGGCTGCTG 
CGTGCTGACG CGGACCTGCC TACGGGGGAA GCTCTCTGGG AATATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Fascin2 regulates cisplatin-induced apoptosis in NRK-52E cells.
Toxicology letters26656-64(2017 Jan)
Wang X,Nichols L,Grunz-Borgmann EA,Sun Z,Meininger GA,Domeier TL,Baines CP,Parrish AR

HCN1 and HCN2 proteins are expressed in cochlear hair cells: HCN1 can form a ternary complex with protocadherin 15 CD3 and F-actin-binding filamin A or can interact with HCN2.
The Journal of biological chemistry287(45)37628-46(2012 Nov)
Ramakrishnan NA,Drescher MJ,Khan KM,Hatfield JS,Drescher DG

The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience30(29)9683-94(2010 Jul)
Shin JB,Longo-Guess CM,Gagnon LH,Saylor KW,Dumont RA,Spinelli KJ,Pagana JM,Wilmarth PA,David LL,Gillespie PG,Johnson KR

Targeted disruption of FSCN2 gene induces retinopathy in mice.
Investigative ophthalmology & visual science46(8)2905-15(2005 Aug)
Yokokura S,Wada Y,Nakai S,Sato H,Yao R,Yamanaka H,Ito S,Sagara Y,Takahashi M,Nakamura Y,Tamai M,Noda T

Mutation of human retinal fascin gene (FSCN2) causes autosomal dominant retinitis pigmentosa.
Investigative ophthalmology & visual science42(10)2395-400(2001 Sep)
Wada Y,Abe T,Takeshita T,Sato H,Yanashima K,Tamai M

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Fscn2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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