Suv39h1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Suv39h1
Entrez Gene ID	302553
Full Name	suppressor of variegation 3-9 homolog 1 (Drosophila)
Synonyms	RGD1565028
General protein information	Preferred Names suppressor of variegation 3-9 homolog 1 (Drosophila) Names histone-lysine N-methyltransferase SUV39H1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq12

mRNA and Protein(s)

mRNA	Protein	Name
XM_006256704.3	XP_006256766.1	histone-lysine N-methyltransferase SUV39H1 isoform X2
NM_001106956.1	NP_001100426.1	histone-lysine N-methyltransferase SUV39H1
XM_006256703.3	XP_006256765.1	histone-lysine N-methyltransferase SUV39H1 isoform X1
XM_006256705.3	XP_006256767.1	histone-lysine N-methyltransferase SUV39H1 isoform X3

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SUV39H1	XP_548987.2
Homo sapiens (human)	SUV39H1	NP_001269095.1
	SUV39H1	XP_001099361.1
Bos taurus (cattle)	SUV39H1	NP_001039729.1
Rattus norvegicus (Norway rat)	Suv39h1	NP_001100426.1
Mus musculus (house mouse)	Suv39h1	NP_035644.1
Gallus gallus (chicken)	SUV39H1	XP_003643945.2
Danio rerio (zebrafish)	suv39h1b	NP_001119954.1

Gene Ontology
Bibliography

Related articles in PubMed

The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction.
Yang G, Weng X, Zhao Y, Zhang X, Hu Y, Dai X, Liang P, Wang P, Ma L, Sun X, Hou L, Xu H, Fang M, Li Y, Jenuwein T, Xu Y, Sun A
Nature communications814941(2017 Mar)

Contribution of the Suppressor of Variegation 3-9 Homolog 1 in Dorsal Root Ganglia and Spinal Cord Dorsal Horn to Nerve Injury-induced Nociceptive Hypersensitivity.
Zhang J, Liang L, Miao X, Wu S, Cao J, Tao B, Mao Q, Mo K, Xiong M, Lutz BM, Bekker A, Tao YX
Anesthesiology125(4)765-78(2016 10)

Suv39h1 protects from myocardial ischemia-reperfusion injury in diabetic rats.
Yang B, Yang J, Bai J, Pu P, Liu J, Wang F, Ruan B
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology33(4)1176-85(2014)

Targeting protein lysine methylation and demethylation in cancers.
He Y, Korboukh I, Jin J, Huang J
Acta biochimica et biophysica Sinica44(1)70-9(2012 Jan)

Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protection.
Bosch-Presegu? L, Raurell-Vila H, Marazuela-Duque A, Kane-Goldsmith N, Valle A, Oliver J, Serrano L, Vaquero A
Molecular cell42(2)210-23(2011 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SUV39H1 plays a critical role in chromosome dynamics and development, neurite outgrowth, and ethanol-induced neuroadaptation through gene-specific silencing.
Title: Contribution of the Suppressor of Variegation 3-9 Homolog 1 in Dorsal Root Ganglia and Spinal Cord Dorsal Horn to Nerve Injury-induced Nociceptive Hypersensitivity.

Overexpression of Suv39h1 results in the de-activation of proinflammatory pathways and reduced apoptosis and myocardial injury.
Title: Suv39h1 protects from myocardial ischemia-reperfusion injury in diabetic rats.

SirT1 preserves heterochromatin structure: it modulates Suv39h1 protein levels in stress conditions by preventing MDM2-mediated polyubiquitination at K87.
Title: Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protection.

mRNA and protein expression of histone methyltransferases G9a and Suv39h1 were directly related to the availability of choline
Title: Gestational choline supply regulates methylation of histone H3, expression of histone methyltransferases G9a (Kmt1c) and Suv39h1 (Kmt1a), and DNA methylation of their genes in rat fetal liver and brain.

Suv4-20h2 and Suv-39h1 histone methyltransferases are expressed and Histone H3 lysine 9 and H4 lysine 20 are trimethylated in hepatocarcinogenesis induced by methyl deficiency in rats [Suv4-20h2 and Suv-39h1]
Title: Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats.

The following Suv39h1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Suv39h1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa02599	NM_001106956.1 Latest version!	Rattus norvegicus suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa02599	XM_006256703.3 Latest version!	Rattus norvegicus suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa39602	XM_006256705.3 Latest version!	Rattus norvegicus suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa39602	XM_006256704.3 Latest version!	Rattus norvegicus suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Suv39h1 ( NM_001106956.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100426.1 Rattus norvegicus suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1), mRNA.

Price & Availability↑

CloneID	ORa02599
Clone ID Related Accession (Same CDS sequence)	NM_001106956.1 , XM_006256703.3
Accession Version	NM_001106956.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1242bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-10
Organism	Rattus norvegicus(Norway rat)
Product	histone-lysine N-methyltransferase SUV39H1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474078.1. On or before Oct 4, 2007 this sequence version replaced XM_217594.4, XM_001063363.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGGGAAC CGGCGACTCT AGGTTGCAGT GTGTGCTGTA AATCTTCCTG GAATCAGCTG 
CAGGATCTGT GCCGACTAGC CAAGCTTTCT TGTCCTGCCC TTGGTGTTTC TAAGAAGAAT 
CTGTATGACT TTGAAGTTGA ATACCTGTGT GATTATAAGA AGATCCGTGA GCAGGAGTAT 
TACCTGGTTA AATGGCGTGG GTATCCTGAC TCAGAGAACA CCTGGGAGCC ACGGCAGAAT 
CTCAAATGTG TGCGCATTCT TAAGCAGTTC CACAAGGACT TAGAAAGAGA GCTTGTCCGG 
CGACACCGCC GGTCAAAGCC ACCCAGGCAT CTGGACCCAA ACTTAGCCAA TTACCTGGTG 
CAGAAGGCCA AGCAGAGGCG GGCACTGCAG CGTTGGGAAC AAGAGCTCAA TGCCAAGCGC 
AGCCATCTGG GGCGGATCAC TGTGGAGAAT GAGGTAGACC TGGATGGCCC TCCAAGGTCC 
TTTGTCTATA TCAATGAGTA TCGAGTTGGT GAGGGCATCA CCCTCAACCA GGTAGCTGTT 
GGCTGTGAGT GCCAGGACTG TCTGTTGGCA CCCACTGGAG GCTGTTGCCC TGGAGCATCC 
CTGCACAAGT TTGCCTACAA TGACCAAGGC CAGGTGCGAC TGAAAGCTGG GCAGCCCATC 
TACGAGTGCA ACTCTCGCTG TTGCTGTGGC TATGACTGCC CAAACCGTGT AGTCCAGAAA 
GGCATCCGCT ACAACCTCTG CATCTTCCGC ACTGATGATG GCCGAGGCTG GGGTGTCCGC 
ACGCTGGAAA AGATCCGCAA AAATAGCTTT GTTATGGAGT ATGTGGGAGA GATTATTACC 
TCAGAGGAGG CAGAGCGGAG GGGCCAGATC TACGACCGCC AGGGCGCCAC CTACCTCTTT 
GACCTGGACT ACGTGGAGGA CGTATATACC GTGGATGCCG CCTATTATGG CAACATCTCT 
CACTTTGTCA ACCATAGTTG TGATCCCAAC CTGCAGGTGT ACAACGTATT CATAGACAAC 
CTTGATGAGC GACTACCCCG CATCGCATTC TTTGCCACAA GAACCATCTG GGCGGGCGAG 
GAGCTCACCT TTGATTACAA CATGCAAGTG GACCCCGTGG ACATGGAGAG TACCCGAATG 
GACTCCAACT TTGGCCTGGC AGGGCTCCCC GGCTCCCCCA AGAAACGGGT CCGTATTGAA 
TGCAAATGTG GGACAACAGC TTGCCGAAAA TACCTCTTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100426.1
CDS	451..1692
Translation	MGEPATLGCSVCCKSSWNQLQDLCRLAKLSCPALGVSKKNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSENTWEPRQNLKCVRILKQFHKDLERELVRRHRRSKPPRHLDPNLANYLVQKAKQRRALQRWEQELNAKRSHLGRITVENEVDLDGPPRSFVYINEYRVGEGITLNQVAVGCECQDCLLAPTGGCCPGASLHKFAYNDQGQVRLKAGQPIYECNSRCCCGYDCPNRVVQKGIRYNLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIWAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTTACRKYLF

Target ORF information:

RefSeq Version	NM_001106956.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106956.1

ORF Insert Sequence:

ATGGGGGAAC CGGCGACTCT AGGTTGCAGT GTGTGCTGTA AATCTTCCTG GAATCAGCTG 
CAGGATCTGT GCCGACTAGC CAAGCTTTCT TGTCCTGCCC TTGGTGTTTC TAAGAAGAAT 
CTGTATGACT TTGAAGTTGA ATACCTGTGT GATTATAAGA AGATCCGTGA GCAGGAGTAT 
TACCTGGTTA AATGGCGTGG GTATCCTGAC TCAGAGAACA CCTGGGAGCC ACGGCAGAAT 
CTCAAATGTG TGCGCATTCT TAAGCAGTTC CACAAGGACT TAGAAAGAGA GCTTGTCCGG 
CGACACCGCC GGTCAAAGCC ACCCAGGCAT CTGGACCCAA ACTTAGCCAA TTACCTGGTG 
CAGAAGGCCA AGCAGAGGCG GGCACTGCAG CGTTGGGAAC AAGAGCTCAA TGCCAAGCGC 
AGCCATCTGG GGCGGATCAC TGTGGAGAAT GAGGTAGACC TGGATGGCCC TCCAAGGTCC 
TTTGTCTATA TCAATGAGTA TCGAGTTGGT GAGGGCATCA CCCTCAACCA GGTAGCTGTT 
GGCTGTGAGT GCCAGGACTG TCTGTTGGCA CCCACTGGAG GCTGTTGCCC TGGAGCATCC 
CTGCACAAGT TTGCCTACAA TGACCAAGGC CAGGTGCGAC TGAAAGCTGG GCAGCCCATC 
TACGAGTGCA ACTCTCGCTG TTGCTGTGGC TATGACTGCC CAAACCGTGT AGTCCAGAAA 
GGCATCCGCT ACAACCTCTG CATCTTCCGC ACTGATGATG GCCGAGGCTG GGGTGTCCGC 
ACGCTGGAAA AGATCCGCAA AAATAGCTTT GTTATGGAGT ATGTGGGAGA GATTATTACC 
TCAGAGGAGG CAGAGCGGAG GGGCCAGATC TACGACCGCC AGGGCGCCAC CTACCTCTTT 
GACCTGGACT ACGTGGAGGA CGTATATACC GTGGATGCCG CCTATTATGG CAACATCTCT 
CACTTTGTCA ACCATAGTTG TGATCCCAAC CTGCAGGTGT ACAACGTATT CATAGACAAC 
CTTGATGAGC GACTACCCCG CATCGCATTC TTTGCCACAA GAACCATCTG GGCGGGCGAG 
GAGCTCACCT TTGATTACAA CATGCAAGTG GACCCCGTGG ACATGGAGAG TACCCGAATG 
GACTCCAACT TTGGCCTGGC AGGGCTCCCC GGCTCCCCCA AGAAACGGGT CCGTATTGAA 
TGCAAATGTG GGACAACAGC TTGCCGAAAA TACCTCTTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Suv39h1 ( XM_006256703.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006256765.1 Rattus norvegicus suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa02599
Clone ID Related Accession (Same CDS sequence)	NM_001106956.1 , XM_006256703.3
Accession Version	XM_006256703.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1242bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	histone-lysine N-methyltransferase SUV39H1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006256703.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGAAC CGGCGACTCT AGGTTGCAGT GTGTGCTGTA AATCTTCCTG GAATCAGCTG 
CAGGATCTGT GCCGACTAGC CAAGCTTTCT TGTCCTGCCC TTGGTGTTTC TAAGAAGAAT 
CTGTATGACT TTGAAGTTGA ATACCTGTGT GATTATAAGA AGATCCGTGA GCAGGAGTAT 
TACCTGGTTA AATGGCGTGG GTATCCTGAC TCAGAGAACA CCTGGGAGCC ACGGCAGAAT 
CTCAAATGTG TGCGCATTCT TAAGCAGTTC CACAAGGACT TAGAAAGAGA GCTTGTCCGG 
CGACACCGCC GGTCAAAGCC ACCCAGGCAT CTGGACCCAA ACTTAGCCAA TTACCTGGTG 
CAGAAGGCCA AGCAGAGGCG GGCACTGCAG CGTTGGGAAC AAGAGCTCAA TGCCAAGCGC 
AGCCATCTGG GGCGGATCAC TGTGGAGAAT GAGGTAGACC TGGATGGCCC TCCAAGGTCC 
TTTGTCTATA TCAATGAGTA TCGAGTTGGT GAGGGCATCA CCCTCAACCA GGTAGCTGTT 
GGCTGTGAGT GCCAGGACTG TCTGTTGGCA CCCACTGGAG GCTGTTGCCC TGGAGCATCC 
CTGCACAAGT TTGCCTACAA TGACCAAGGC CAGGTGCGAC TGAAAGCTGG GCAGCCCATC 
TACGAGTGCA ACTCTCGCTG TTGCTGTGGC TATGACTGCC CAAACCGTGT AGTCCAGAAA 
GGCATCCGCT ACAACCTCTG CATCTTCCGC ACTGATGATG GCCGAGGCTG GGGTGTCCGC 
ACGCTGGAAA AGATCCGCAA AAATAGCTTT GTTATGGAGT ATGTGGGAGA GATTATTACC 
TCAGAGGAGG CAGAGCGGAG GGGCCAGATC TACGACCGCC AGGGCGCCAC CTACCTCTTT 
GACCTGGACT ACGTGGAGGA CGTATATACC GTGGATGCCG CCTATTATGG CAACATCTCT 
CACTTTGTCA ACCATAGTTG TGATCCCAAC CTGCAGGTGT ACAACGTATT CATAGACAAC 
CTTGATGAGC GACTACCCCG CATCGCATTC TTTGCCACAA GAACCATCTG GGCGGGCGAG 
GAGCTCACCT TTGATTACAA CATGCAAGTG GACCCCGTGG ACATGGAGAG TACCCGAATG 
GACTCCAACT TTGGCCTGGC AGGGCTCCCC GGCTCCCCCA AGAAACGGGT CCGTATTGAA 
TGCAAATGTG GGACAACAGC TTGCCGAAAA TACCTCTTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006256765.1
CDS	668..1909
Translation	MGEPATLGCSVCCKSSWNQLQDLCRLAKLSCPALGVSKKNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSENTWEPRQNLKCVRILKQFHKDLERELVRRHRRSKPPRHLDPNLANYLVQKAKQRRALQRWEQELNAKRSHLGRITVENEVDLDGPPRSFVYINEYRVGEGITLNQVAVGCECQDCLLAPTGGCCPGASLHKFAYNDQGQVRLKAGQPIYECNSRCCCGYDCPNRVVQKGIRYNLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIWAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTTACRKYLF

Target ORF information:

RefSeq Version	XM_006256703.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006256703.3

ORF Insert Sequence:

ATGGGGGAAC CGGCGACTCT AGGTTGCAGT GTGTGCTGTA AATCTTCCTG GAATCAGCTG 
CAGGATCTGT GCCGACTAGC CAAGCTTTCT TGTCCTGCCC TTGGTGTTTC TAAGAAGAAT 
CTGTATGACT TTGAAGTTGA ATACCTGTGT GATTATAAGA AGATCCGTGA GCAGGAGTAT 
TACCTGGTTA AATGGCGTGG GTATCCTGAC TCAGAGAACA CCTGGGAGCC ACGGCAGAAT 
CTCAAATGTG TGCGCATTCT TAAGCAGTTC CACAAGGACT TAGAAAGAGA GCTTGTCCGG 
CGACACCGCC GGTCAAAGCC ACCCAGGCAT CTGGACCCAA ACTTAGCCAA TTACCTGGTG 
CAGAAGGCCA AGCAGAGGCG GGCACTGCAG CGTTGGGAAC AAGAGCTCAA TGCCAAGCGC 
AGCCATCTGG GGCGGATCAC TGTGGAGAAT GAGGTAGACC TGGATGGCCC TCCAAGGTCC 
TTTGTCTATA TCAATGAGTA TCGAGTTGGT GAGGGCATCA CCCTCAACCA GGTAGCTGTT 
GGCTGTGAGT GCCAGGACTG TCTGTTGGCA CCCACTGGAG GCTGTTGCCC TGGAGCATCC 
CTGCACAAGT TTGCCTACAA TGACCAAGGC CAGGTGCGAC TGAAAGCTGG GCAGCCCATC 
TACGAGTGCA ACTCTCGCTG TTGCTGTGGC TATGACTGCC CAAACCGTGT AGTCCAGAAA 
GGCATCCGCT ACAACCTCTG CATCTTCCGC ACTGATGATG GCCGAGGCTG GGGTGTCCGC 
ACGCTGGAAA AGATCCGCAA AAATAGCTTT GTTATGGAGT ATGTGGGAGA GATTATTACC 
TCAGAGGAGG CAGAGCGGAG GGGCCAGATC TACGACCGCC AGGGCGCCAC CTACCTCTTT 
GACCTGGACT ACGTGGAGGA CGTATATACC GTGGATGCCG CCTATTATGG CAACATCTCT 
CACTTTGTCA ACCATAGTTG TGATCCCAAC CTGCAGGTGT ACAACGTATT CATAGACAAC 
CTTGATGAGC GACTACCCCG CATCGCATTC TTTGCCACAA GAACCATCTG GGCGGGCGAG 
GAGCTCACCT TTGATTACAA CATGCAAGTG GACCCCGTGG ACATGGAGAG TACCCGAATG 
GACTCCAACT TTGGCCTGGC AGGGCTCCCC GGCTCCCCCA AGAAACGGGT CCGTATTGAA 
TGCAAATGTG GGACAACAGC TTGCCGAAAA TACCTCTTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Suv39h1 ( XM_006256704.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006256766.1 Rattus norvegicus suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa39602
Clone ID Related Accession (Same CDS sequence)	XM_006256704.3 , XM_006256705.3
Accession Version	XM_006256704.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1239bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	histone-lysine N-methyltransferase SUV39H1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006256704.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGAAA ATTTAAAAGG TTGCAGTGTG TGCTGTAAAT CTTCCTGGAA TCAGCTGCAG 
GATCTGTGCC GACTAGCCAA GCTTTCTTGT CCTGCCCTTG GTGTTTCTAA GAAGAATCTG 
TATGACTTTG AAGTTGAATA CCTGTGTGAT TATAAGAAGA TCCGTGAGCA GGAGTATTAC 
CTGGTTAAAT GGCGTGGGTA TCCTGACTCA GAGAACACCT GGGAGCCACG GCAGAATCTC 
AAATGTGTGC GCATTCTTAA GCAGTTCCAC AAGGACTTAG AAAGAGAGCT TGTCCGGCGA 
CACCGCCGGT CAAAGCCACC CAGGCATCTG GACCCAAACT TAGCCAATTA CCTGGTGCAG 
AAGGCCAAGC AGAGGCGGGC ACTGCAGCGT TGGGAACAAG AGCTCAATGC CAAGCGCAGC 
CATCTGGGGC GGATCACTGT GGAGAATGAG GTAGACCTGG ATGGCCCTCC AAGGTCCTTT 
GTCTATATCA ATGAGTATCG AGTTGGTGAG GGCATCACCC TCAACCAGGT AGCTGTTGGC 
TGTGAGTGCC AGGACTGTCT GTTGGCACCC ACTGGAGGCT GTTGCCCTGG AGCATCCCTG 
CACAAGTTTG CCTACAATGA CCAAGGCCAG GTGCGACTGA AAGCTGGGCA GCCCATCTAC 
GAGTGCAACT CTCGCTGTTG CTGTGGCTAT GACTGCCCAA ACCGTGTAGT CCAGAAAGGC 
ATCCGCTACA ACCTCTGCAT CTTCCGCACT GATGATGGCC GAGGCTGGGG TGTCCGCACG 
CTGGAAAAGA TCCGCAAAAA TAGCTTTGTT ATGGAGTATG TGGGAGAGAT TATTACCTCA 
GAGGAGGCAG AGCGGAGGGG CCAGATCTAC GACCGCCAGG GCGCCACCTA CCTCTTTGAC 
CTGGACTACG TGGAGGACGT ATATACCGTG GATGCCGCCT ATTATGGCAA CATCTCTCAC 
TTTGTCAACC ATAGTTGTGA TCCCAACCTG CAGGTGTACA ACGTATTCAT AGACAACCTT 
GATGAGCGAC TACCCCGCAT CGCATTCTTT GCCACAAGAA CCATCTGGGC GGGCGAGGAG 
CTCACCTTTG ATTACAACAT GCAAGTGGAC CCCGTGGACA TGGAGAGTAC CCGAATGGAC 
TCCAACTTTG GCCTGGCAGG GCTCCCCGGC TCCCCCAAGA AACGGGTCCG TATTGAATGC 
AAATGTGGGA CAACAGCTTG CCGAAAATAC CTCTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006256766.1
CDS	247..1485
Translation	MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGVSKKNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSENTWEPRQNLKCVRILKQFHKDLERELVRRHRRSKPPRHLDPNLANYLVQKAKQRRALQRWEQELNAKRSHLGRITVENEVDLDGPPRSFVYINEYRVGEGITLNQVAVGCECQDCLLAPTGGCCPGASLHKFAYNDQGQVRLKAGQPIYECNSRCCCGYDCPNRVVQKGIRYNLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIWAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTTACRKYLF

Target ORF information:

RefSeq Version	XM_006256704.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006256704.3

ORF Insert Sequence:

ATGGCGGAAA ATTTAAAAGG TTGCAGTGTG TGCTGTAAAT CTTCCTGGAA TCAGCTGCAG 
GATCTGTGCC GACTAGCCAA GCTTTCTTGT CCTGCCCTTG GTGTTTCTAA GAAGAATCTG 
TATGACTTTG AAGTTGAATA CCTGTGTGAT TATAAGAAGA TCCGTGAGCA GGAGTATTAC 
CTGGTTAAAT GGCGTGGGTA TCCTGACTCA GAGAACACCT GGGAGCCACG GCAGAATCTC 
AAATGTGTGC GCATTCTTAA GCAGTTCCAC AAGGACTTAG AAAGAGAGCT TGTCCGGCGA 
CACCGCCGGT CAAAGCCACC CAGGCATCTG GACCCAAACT TAGCCAATTA CCTGGTGCAG 
AAGGCCAAGC AGAGGCGGGC ACTGCAGCGT TGGGAACAAG AGCTCAATGC CAAGCGCAGC 
CATCTGGGGC GGATCACTGT GGAGAATGAG GTAGACCTGG ATGGCCCTCC AAGGTCCTTT 
GTCTATATCA ATGAGTATCG AGTTGGTGAG GGCATCACCC TCAACCAGGT AGCTGTTGGC 
TGTGAGTGCC AGGACTGTCT GTTGGCACCC ACTGGAGGCT GTTGCCCTGG AGCATCCCTG 
CACAAGTTTG CCTACAATGA CCAAGGCCAG GTGCGACTGA AAGCTGGGCA GCCCATCTAC 
GAGTGCAACT CTCGCTGTTG CTGTGGCTAT GACTGCCCAA ACCGTGTAGT CCAGAAAGGC 
ATCCGCTACA ACCTCTGCAT CTTCCGCACT GATGATGGCC GAGGCTGGGG TGTCCGCACG 
CTGGAAAAGA TCCGCAAAAA TAGCTTTGTT ATGGAGTATG TGGGAGAGAT TATTACCTCA 
GAGGAGGCAG AGCGGAGGGG CCAGATCTAC GACCGCCAGG GCGCCACCTA CCTCTTTGAC 
CTGGACTACG TGGAGGACGT ATATACCGTG GATGCCGCCT ATTATGGCAA CATCTCTCAC 
TTTGTCAACC ATAGTTGTGA TCCCAACCTG CAGGTGTACA ACGTATTCAT AGACAACCTT 
GATGAGCGAC TACCCCGCAT CGCATTCTTT GCCACAAGAA CCATCTGGGC GGGCGAGGAG 
CTCACCTTTG ATTACAACAT GCAAGTGGAC CCCGTGGACA TGGAGAGTAC CCGAATGGAC 
TCCAACTTTG GCCTGGCAGG GCTCCCCGGC TCCCCCAAGA AACGGGTCCG TATTGAATGC 
AAATGTGGGA CAACAGCTTG CCGAAAATAC CTCTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Suv39h1 ( XM_006256705.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006256767.1 Rattus norvegicus suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1), transcript variant X3, mRNA.

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CloneID	ORa39602
Clone ID Related Accession (Same CDS sequence)	XM_006256704.3 , XM_006256705.3
Accession Version	XM_006256705.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1239bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	histone-lysine N-methyltransferase SUV39H1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006256705.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGAAA ATTTAAAAGG TTGCAGTGTG TGCTGTAAAT CTTCCTGGAA TCAGCTGCAG 
GATCTGTGCC GACTAGCCAA GCTTTCTTGT CCTGCCCTTG GTGTTTCTAA GAAGAATCTG 
TATGACTTTG AAGTTGAATA CCTGTGTGAT TATAAGAAGA TCCGTGAGCA GGAGTATTAC 
CTGGTTAAAT GGCGTGGGTA TCCTGACTCA GAGAACACCT GGGAGCCACG GCAGAATCTC 
AAATGTGTGC GCATTCTTAA GCAGTTCCAC AAGGACTTAG AAAGAGAGCT TGTCCGGCGA 
CACCGCCGGT CAAAGCCACC CAGGCATCTG GACCCAAACT TAGCCAATTA CCTGGTGCAG 
AAGGCCAAGC AGAGGCGGGC ACTGCAGCGT TGGGAACAAG AGCTCAATGC CAAGCGCAGC 
CATCTGGGGC GGATCACTGT GGAGAATGAG GTAGACCTGG ATGGCCCTCC AAGGTCCTTT 
GTCTATATCA ATGAGTATCG AGTTGGTGAG GGCATCACCC TCAACCAGGT AGCTGTTGGC 
TGTGAGTGCC AGGACTGTCT GTTGGCACCC ACTGGAGGCT GTTGCCCTGG AGCATCCCTG 
CACAAGTTTG CCTACAATGA CCAAGGCCAG GTGCGACTGA AAGCTGGGCA GCCCATCTAC 
GAGTGCAACT CTCGCTGTTG CTGTGGCTAT GACTGCCCAA ACCGTGTAGT CCAGAAAGGC 
ATCCGCTACA ACCTCTGCAT CTTCCGCACT GATGATGGCC GAGGCTGGGG TGTCCGCACG 
CTGGAAAAGA TCCGCAAAAA TAGCTTTGTT ATGGAGTATG TGGGAGAGAT TATTACCTCA 
GAGGAGGCAG AGCGGAGGGG CCAGATCTAC GACCGCCAGG GCGCCACCTA CCTCTTTGAC 
CTGGACTACG TGGAGGACGT ATATACCGTG GATGCCGCCT ATTATGGCAA CATCTCTCAC 
TTTGTCAACC ATAGTTGTGA TCCCAACCTG CAGGTGTACA ACGTATTCAT AGACAACCTT 
GATGAGCGAC TACCCCGCAT CGCATTCTTT GCCACAAGAA CCATCTGGGC GGGCGAGGAG 
CTCACCTTTG ATTACAACAT GCAAGTGGAC CCCGTGGACA TGGAGAGTAC CCGAATGGAC 
TCCAACTTTG GCCTGGCAGG GCTCCCCGGC TCCCCCAAGA AACGGGTCCG TATTGAATGC 
AAATGTGGGA CAACAGCTTG CCGAAAATAC CTCTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006256767.1
CDS	248..1486
Translation	MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGVSKKNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSENTWEPRQNLKCVRILKQFHKDLERELVRRHRRSKPPRHLDPNLANYLVQKAKQRRALQRWEQELNAKRSHLGRITVENEVDLDGPPRSFVYINEYRVGEGITLNQVAVGCECQDCLLAPTGGCCPGASLHKFAYNDQGQVRLKAGQPIYECNSRCCCGYDCPNRVVQKGIRYNLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIWAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTTACRKYLF

Target ORF information:

RefSeq Version	XM_006256705.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006256705.3

ORF Insert Sequence:

ATGGCGGAAA ATTTAAAAGG TTGCAGTGTG TGCTGTAAAT CTTCCTGGAA TCAGCTGCAG 
GATCTGTGCC GACTAGCCAA GCTTTCTTGT CCTGCCCTTG GTGTTTCTAA GAAGAATCTG 
TATGACTTTG AAGTTGAATA CCTGTGTGAT TATAAGAAGA TCCGTGAGCA GGAGTATTAC 
CTGGTTAAAT GGCGTGGGTA TCCTGACTCA GAGAACACCT GGGAGCCACG GCAGAATCTC 
AAATGTGTGC GCATTCTTAA GCAGTTCCAC AAGGACTTAG AAAGAGAGCT TGTCCGGCGA 
CACCGCCGGT CAAAGCCACC CAGGCATCTG GACCCAAACT TAGCCAATTA CCTGGTGCAG 
AAGGCCAAGC AGAGGCGGGC ACTGCAGCGT TGGGAACAAG AGCTCAATGC CAAGCGCAGC 
CATCTGGGGC GGATCACTGT GGAGAATGAG GTAGACCTGG ATGGCCCTCC AAGGTCCTTT 
GTCTATATCA ATGAGTATCG AGTTGGTGAG GGCATCACCC TCAACCAGGT AGCTGTTGGC 
TGTGAGTGCC AGGACTGTCT GTTGGCACCC ACTGGAGGCT GTTGCCCTGG AGCATCCCTG 
CACAAGTTTG CCTACAATGA CCAAGGCCAG GTGCGACTGA AAGCTGGGCA GCCCATCTAC 
GAGTGCAACT CTCGCTGTTG CTGTGGCTAT GACTGCCCAA ACCGTGTAGT CCAGAAAGGC 
ATCCGCTACA ACCTCTGCAT CTTCCGCACT GATGATGGCC GAGGCTGGGG TGTCCGCACG 
CTGGAAAAGA TCCGCAAAAA TAGCTTTGTT ATGGAGTATG TGGGAGAGAT TATTACCTCA 
GAGGAGGCAG AGCGGAGGGG CCAGATCTAC GACCGCCAGG GCGCCACCTA CCTCTTTGAC 
CTGGACTACG TGGAGGACGT ATATACCGTG GATGCCGCCT ATTATGGCAA CATCTCTCAC 
TTTGTCAACC ATAGTTGTGA TCCCAACCTG CAGGTGTACA ACGTATTCAT AGACAACCTT 
GATGAGCGAC TACCCCGCAT CGCATTCTTT GCCACAAGAA CCATCTGGGC GGGCGAGGAG 
CTCACCTTTG ATTACAACAT GCAAGTGGAC CCCGTGGACA TGGAGAGTAC CCGAATGGAC 
TCCAACTTTG GCCTGGCAGG GCTCCCCGGC TCCCCCAAGA AACGGGTCCG TATTGAATGC 
AAATGTGGGA CAACAGCTTG CCGAAAATAC CTCTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction.
Nature communications814941(2017 Mar)
Yang G,Weng X,Zhao Y,Zhang X,Hu Y,Dai X,Liang P,Wang P,Ma L,Sun X,Hou L,Xu H,Fang M,Li Y,Jenuwein T,Xu Y,Sun A

Contribution of the Suppressor of Variegation 3-9 Homolog 1 in Dorsal Root Ganglia and Spinal Cord Dorsal Horn to Nerve Injury-induced Nociceptive Hypersensitivity.
Anesthesiology125(4)765-78(2016 10)
Zhang J,Liang L,Miao X,Wu S,Cao J,Tao B,Mao Q,Mo K,Xiong M,Lutz BM,Bekker A,Tao YX

Suv39h1 protects from myocardial ischemia-reperfusion injury in diabetic rats.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology33(4)1176-85(2014)
Yang B,Yang J,Bai J,Pu P,Liu J,Wang F,Ruan B

Targeting protein lysine methylation and demethylation in cancers.
Acta biochimica et biophysica Sinica44(1)70-9(2012 Jan)
He Y,Korboukh I,Jin J,Huang J

Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protection.
Molecular cell42(2)210-23(2011 Apr)
Bosch-Presegu? L,Raurell-Vila H,Marazuela-Duque A,Kane-Goldsmith N,Valle A,Oliver J,Serrano L,Vaquero A

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Suv39h1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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