Ltf cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ltf
Entrez Gene ID	301034
Full Name	lactotransferrin
General protein information	Preferred Names lactotransferrin Names lactotransferrin lactoferrin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q32

mRNA and Protein(s)

mRNA	Protein	Name
NM_001106864.1	NP_001100334.1	lactotransferrin precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	LTF	XP_541903.2
Bos taurus (cattle)	LTF	NP_851341.1
Pan troglodytes (chimpanzee)	LTF	XP_516417.2
Mus musculus (house mouse)	Ltf	NP_032548.2
Rattus norvegicus (Norway rat)	Ltf	NP_001100334.1
Homo sapiens (human)	LTF	NP_002334.2

Gene Ontology
Bibliography

Related articles in PubMed

Lactoferrin during lactation reduces lipopolysaccharide-induced brain injury.
Ginet V, van de Looij Y, Petrenko V, Toulotte A, Kiss J, H?ppi PS, Sizonenko SV
BioFactors (Oxford, England)42(3)323-36(2016 May)

The intracellular inhibition of HCV replication represents a novel mechanism of action by the innate immune Lactoferrin protein.
Picard-Jean F, Bouchard S, Lariv?e G, Bisaillon M
Antiviral research11113-22(2014 Nov)

Lactoferrin ameliorates prostaglandin E2-mediated inhibition of Na+ -glucose cotransport in enterocytes.
Talukder JR, Griffin A, Jaima A, Boyd B, Wright J
Canadian journal of physiology and pharmacology92(1)9-20(2014 Jan)

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma na?ve to therapy.
Pieragostino D, Agnifili L, Fasanella V, D'Aguanno S, Mastropasqua R, Di Ilio C, Sacchetta P, Urbani A, Del Boccio P
Molecular bioSystems9(6)1108-16(2013 Jun)

A phase 2 randomized, double-blind, placebo-controlled study of the safety and efficacy of talactoferrin in patients with severe sepsis.
Guntupalli K, Dean N, Morris PE, Bandi V, Margolis B, Rivers E, Levy M, Lodato RF, Ismail PM, Reese A, Schaumberg JP, Malik R, Dellinger RP,
Critical care medicine41(3)706-16(2013 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Lf supplemented in food during lactation attenuated acute and long-term cerebral LPS-induced alterations. This provides a new evidence for a promising use of Lf as a preventive neuroprotective approach in preterm encephalopathy.
Title: Lactoferrin during lactation reduces lipopolysaccharide-induced brain injury.

Lactoferrin ameliorates the prostaglandin E2 inhibition of Na(+)-glucose cotransport most likely via the Ca(2+)- and cAMP-signaling pathways.
Title: Lactoferrin ameliorates prostaglandin E2-mediated inhibition of Na+ -glucose cotransport in enterocytes.

lactoferrin promotes rat osteoblastic cell survival by inducing cell proliferation and inhibiting apoptosis
Title: Lactoferrin potently inhibits osteoblast apoptosis, via an LRP1-independent pathway.

differential expression and estrogen responsiveness of the lactoferrin gene in different regions of the female reproductive tract [Lactoferrin]
Title: Differential expression and estrogen response of lactoferrin gene in the female reproductive tract of mouse, rat, and hamster.

The following Ltf gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ltf cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42254	NM_001106864.1 Latest version!	Rattus norvegicus lactotransferrin (Ltf), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ltf ( NM_001106864.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100334.1 Rattus norvegicus lactotransferrin (Ltf), mRNA.

Price & Availability↑

CloneID	ORa42254
Clone ID Related Accession (Same CDS sequence)	NM_001106864.1
Accession Version	NM_001106864.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2130bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Rattus norvegicus(Norway rat)
Product	lactotransferrin precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473954.2. On or before Oct 4, 2007 this sequence version replaced XM_001076267.1, XM_236657.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052297, SAMEA2689601 [ECO:0000350] ##Evidence-Data-END##

ATGAGGCCGT TCATCACTGT CTTGATGTTT CTTGGGGTCC TTGGACCCTT TCTAGCTAGG 
ATAGATACAG TTGTTCGATG GTGCACCATA TCAAGAAATG AGGCACAAAA ATGTTTCATG 
TGGCAAGAGA TGCTGAACAA AGCGGGTGTC CCGAAGCTTA GATGTGCCAG GAAGTACTTC 
ATGCCTCACT GTATCCAGGA GATTATGATG AGGAGAGCCG ACGCCATGAC TCTTTCTGGC 
AGCGCCATAT TCGATTTCTA TTTTCCCTAC AAACTGCAGC CGATAGCTGC CGAAGTCTAT 
GGAACCAAAG AGAAGCCCCG GATTCACTAT TATGCGGTGG CCGTCGTGAA GAACAGCAGT 
GACATTCGTC TGAACCAACT CCAAGGCTTG AAGTCCTGCC ATGCAGGCTT TGACACTAGT 
GCAGGGTGGA TAGCCCCTTT AGGGGCACTT CGTCCATACC TGAATTGGGA TGAGAAATCT 
GTATCCCTTG AGGAAGCGGT ATCCAAGTTC TTCTCACAGA GCTGTGTTCC TGGTATCAGC 
AAGTCTAGAT TTCCCAGGTT GTGTAGCTTG TGTGCAGGGA AAGGAGAACA CATATGTGAC 
TTTTCCCCCC AGGAACCATA CGCTGGCTAC GCAGGTGCCT TCAGGTGTCT GAGAGACAAC 
GCTGGAGATG TGGCTTTTAT CAGAGAAAGC ACGATATTTG AGGAGTTACC CAATGAAGCT 
GAATGGGACC AGTACAAGCT GCTTTGCCCA GATAACACCT GGAAGCCGGT GACAGAGTAC 
AAGGAGTGCC ACCTGGCTCA AATCCCTTCA CGTGCTGTCG TAGCCCATGT CAGAAGTGAA 
AAAGACAGTG CCATCTGGGA GCTTCTCCAC CTGTCACAGG AAATGTTTGG AAAAAACAAA 
ACATCAAAAT TCGAGCTCTT TGGCTCCTAT CTGGGACAGA AGGACCTGCT GTTCAAGGAC 
TCTGTCATTG GCTTTGTGAG GGTTCCCTTT ACAGTGAATG TTTGGCTTTA CCTGACCTTC 
AGTTATATCA TGGCCCTGAA GAGCTTGAAG GAAAGCAAGG AGAATGTGAT GGCCTTAAGG 
GCCCGGATCA CGTGGTGTGC CGTGGGCAGT GAGGAGAAGC TCAAGTGTGA CCAGTGGAGC 
AGAGTGAGTG TTGGCAAGAT TACCTGCATC TCATGCACCA CCACGGAGCA GTGCATCTTC 
TCTATCACGA TGGGAGATGC TGATGCCATG AACTTGGATG GAGGCTATAT CTACTCTGCG 
GGCAAGTGTG GTTTAGTTCC AGTTTTGGCA GAGATCCAGA AATCCCCCAA TAGCAATGGC 
TCTGATTGTG TGGACAGACC AGCAGAAGGG TACCTTGCTG TAGCCGCAGT CAGAAAAGAA 
GATACTGGCT TCACCTGGAG CACTGTGAGA GGGAAGAAAT CCTGCCACAC CGCTGTGGAC 
AGGACCGCGG GCTGGAACAT TCCCATGGGC CTGCTTGTCA ACCAGACCAA CTCCTGCCAA 
TTTAAGGAAT TCTTTAACAA AAGCTGCGCC CCTGGGTCTT TCCTCTATTC CAATCTCTGT 
GCCCTGTGTA TTGGTGACGA GAACGGTAAG GATAAGTGTA ACCCCAACAG CCAAGAGAGG 
TACCAAGGCT ACGTCGGGGC TTTCAGGTGT CTGGCTGAGA AGGCAGGAAA TGTCGCGTTT 
TTGAAGGACG CCACTGTCTT GCAGAATACA GACGGGAAGA ATGCTGACAA GTGGGCTAAG 
AACTTGAAGC TGGATGACTT CGAGCTGTTG TGCCTTGATG ACACCCGGAA GCCTGTGACT 
GAGGCTAAGA ACTGCCACCT AGCCGTAGCC CCAAACCATG CTGTAGTAGC TCGGAAGGAC 
AAGGCGAGAC TCGTTCAGCA AGAGCTGCTT TACCAACAGG TTCAGTTTGG GAGAAATGGA 
TGCAGGTGTC CAGAAGAGTT TTGCCTGTTC AGGTCTGAAA CCAAAAACCT TCTGTTCAAT 
GACAACACTG AGTGTCTGGC CAAGCTCCCC AGCAAAATCA CATGGGAGGA ATATCTAGGC 
AAGGAGTACG TCGTAGCGAT CGCGCATCTG AGGCAGTGCT CCAATATCAC TCAGGAAGCC 
TACAATTTTC TTGCCCTTCG AAACTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100334.1
CDS	39..2168
Translation	MRPFITVLMFLGVLGPFLARIDTVVRWCTISRNEAQKCFMWQEMLNKAGVPKLRCARKYFMPHCIQEIMMRRADAMTLSGSAIFDFYFPYKLQPIAAEVYGTKEKPRIHYYAVAVVKNSSDIRLNQLQGLKSCHAGFDTSAGWIAPLGALRPYLNWDEKSVSLEEAVSKFFSQSCVPGISKSRFPRLCSLCAGKGEHICDFSPQEPYAGYAGAFRCLRDNAGDVAFIRESTIFEELPNEAEWDQYKLLCPDNTWKPVTEYKECHLAQIPSRAVVAHVRSEKDSAIWELLHLSQEMFGKNKTSKFELFGSYLGQKDLLFKDSVIGFVRVPFTVNVWLYLTFSYIMALKSLKESKENVMALRARITWCAVGSEEKLKCDQWSRVSVGKITCISCTTTEQCIFSITMGDADAMNLDGGYIYSAGKCGLVPVLAEIQKSPNSNGSDCVDRPAEGYLAVAAVRKEDTGFTWSTVRGKKSCHTAVDRTAGWNIPMGLLVNQTNSCQFKEFFNKSCAPGSFLYSNLCALCIGDENGKDKCNPNSQERYQGYVGAFRCLAEKAGNVAFLKDATVLQNTDGKNADKWAKNLKLDDFELLCLDDTRKPVTEAKNCHLAVAPNHAVVARKDKARLVQQELLYQQVQFGRNGCRCPEEFCLFRSETKNLLFNDNTECLAKLPSKITWEEYLGKEYVVAIAHLRQCSNITQEAYNFLALRNS

Target ORF information:

RefSeq Version	NM_001106864.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lactotransferrin (Ltf), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106864.1

ORF Insert Sequence:

ATGAGGCCGT TCATCACTGT CTTGATGTTT CTTGGGGTCC TTGGACCCTT TCTAGCTAGG 
ATAGATACAG TTGTTCGATG GTGCACCATA TCAAGAAATG AGGCACAAAA ATGTTTCATG 
TGGCAAGAGA TGCTGAACAA AGCGGGTGTC CCGAAGCTTA GATGTGCCAG GAAGTACTTC 
ATGCCTCACT GTATCCAGGA GATTATGATG AGGAGAGCCG ACGCCATGAC TCTTTCTGGC 
AGCGCCATAT TCGATTTCTA TTTTCCCTAC AAACTGCAGC CGATAGCTGC CGAAGTCTAT 
GGAACCAAAG AGAAGCCCCG GATTCACTAT TATGCGGTGG CCGTCGTGAA GAACAGCAGT 
GACATTCGTC TGAACCAACT CCAAGGCTTG AAGTCCTGCC ATGCAGGCTT TGACACTAGT 
GCAGGGTGGA TAGCCCCTTT AGGGGCACTT CGTCCATACC TGAATTGGGA TGAGAAATCT 
GTATCCCTTG AGGAAGCGGT ATCCAAGTTC TTCTCACAGA GCTGTGTTCC TGGTATCAGC 
AAGTCTAGAT TTCCCAGGTT GTGTAGCTTG TGTGCAGGGA AAGGAGAACA CATATGTGAC 
TTTTCCCCCC AGGAACCATA CGCTGGCTAC GCAGGTGCCT TCAGGTGTCT GAGAGACAAC 
GCTGGAGATG TGGCTTTTAT CAGAGAAAGC ACGATATTTG AGGAGTTACC CAATGAAGCT 
GAATGGGACC AGTACAAGCT GCTTTGCCCA GATAACACCT GGAAGCCGGT GACAGAGTAC 
AAGGAGTGCC ACCTGGCTCA AATCCCTTCA CGTGCTGTCG TAGCCCATGT CAGAAGTGAA 
AAAGACAGTG CCATCTGGGA GCTTCTCCAC CTGTCACAGG AAATGTTTGG AAAAAACAAA 
ACATCAAAAT TCGAGCTCTT TGGCTCCTAT CTGGGACAGA AGGACCTGCT GTTCAAGGAC 
TCTGTCATTG GCTTTGTGAG GGTTCCCTTT ACAGTGAATG TTTGGCTTTA CCTGACCTTC 
AGTTATATCA TGGCCCTGAA GAGCTTGAAG GAAAGCAAGG AGAATGTGAT GGCCTTAAGG 
GCCCGGATCA CGTGGTGTGC CGTGGGCAGT GAGGAGAAGC TCAAGTGTGA CCAGTGGAGC 
AGAGTGAGTG TTGGCAAGAT TACCTGCATC TCATGCACCA CCACGGAGCA GTGCATCTTC 
TCTATCACGA TGGGAGATGC TGATGCCATG AACTTGGATG GAGGCTATAT CTACTCTGCG 
GGCAAGTGTG GTTTAGTTCC AGTTTTGGCA GAGATCCAGA AATCCCCCAA TAGCAATGGC 
TCTGATTGTG TGGACAGACC AGCAGAAGGG TACCTTGCTG TAGCCGCAGT CAGAAAAGAA 
GATACTGGCT TCACCTGGAG CACTGTGAGA GGGAAGAAAT CCTGCCACAC CGCTGTGGAC 
AGGACCGCGG GCTGGAACAT TCCCATGGGC CTGCTTGTCA ACCAGACCAA CTCCTGCCAA 
TTTAAGGAAT TCTTTAACAA AAGCTGCGCC CCTGGGTCTT TCCTCTATTC CAATCTCTGT 
GCCCTGTGTA TTGGTGACGA GAACGGTAAG GATAAGTGTA ACCCCAACAG CCAAGAGAGG 
TACCAAGGCT ACGTCGGGGC TTTCAGGTGT CTGGCTGAGA AGGCAGGAAA TGTCGCGTTT 
TTGAAGGACG CCACTGTCTT GCAGAATACA GACGGGAAGA ATGCTGACAA GTGGGCTAAG 
AACTTGAAGC TGGATGACTT CGAGCTGTTG TGCCTTGATG ACACCCGGAA GCCTGTGACT 
GAGGCTAAGA ACTGCCACCT AGCCGTAGCC CCAAACCATG CTGTAGTAGC TCGGAAGGAC 
AAGGCGAGAC TCGTTCAGCA AGAGCTGCTT TACCAACAGG TTCAGTTTGG GAGAAATGGA 
TGCAGGTGTC CAGAAGAGTT TTGCCTGTTC AGGTCTGAAA CCAAAAACCT TCTGTTCAAT 
GACAACACTG AGTGTCTGGC CAAGCTCCCC AGCAAAATCA CATGGGAGGA ATATCTAGGC 
AAGGAGTACG TCGTAGCGAT CGCGCATCTG AGGCAGTGCT CCAATATCAC TCAGGAAGCC 
TACAATTTTC TTGCCCTTCG AAACTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lactoferrin during lactation reduces lipopolysaccharide-induced brain injury.
BioFactors (Oxford, England)42(3)323-36(2016 May)
Ginet V,van de Looij Y,Petrenko V,Toulotte A,Kiss J,H?ppi PS,Sizonenko SV

The intracellular inhibition of HCV replication represents a novel mechanism of action by the innate immune Lactoferrin protein.
Antiviral research11113-22(2014 Nov)
Picard-Jean F,Bouchard S,Lariv?e G,Bisaillon M

Lactoferrin ameliorates prostaglandin E2-mediated inhibition of Na+ -glucose cotransport in enterocytes.
Canadian journal of physiology and pharmacology92(1)9-20(2014 Jan)
Talukder JR,Griffin A,Jaima A,Boyd B,Wright J

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma na?ve to therapy.
Molecular bioSystems9(6)1108-16(2013 Jun)
Pieragostino D,Agnifili L,Fasanella V,D'Aguanno S,Mastropasqua R,Di Ilio C,Sacchetta P,Urbani A,Del Boccio P

A phase 2 randomized, double-blind, placebo-controlled study of the safety and efficacy of talactoferrin in patients with severe sepsis.
Critical care medicine41(3)706-16(2013 Mar)
Guntupalli K,Dean N,Morris PE,Bandi V,Margolis B,Rivers E,Levy M,Lodato RF,Ismail PM,Reese A,Schaumberg JP,Malik R,Dellinger RP,

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Ltf cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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