Snx17 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Snx17
Entrez Gene ID	298836
Full Name	sorting nexin 17
General protein information	Preferred Names sorting nexin 17 Names sorting nexin-17
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q14

mRNA and Protein(s)

mRNA	Protein	Name
NM_001011981.1	NP_001011981.1	sorting nexin-17

Pathways from BioSystems

Homologies

Homo sapiens (human)	SNX17	NP_055563.1
Canis lupus familiaris (dog)	SNX17	XP_540126.2
Bos taurus (cattle)	SNX17	NP_001015638.1
Mus musculus (house mouse)	Snx17	NP_710147.1
Caenorhabditis elegans (roundworm)	snx-17	NP_001076763.1
Pan troglodytes (chimpanzee)	SNX17	XP_515357.3
Gallus gallus (chicken)	SNX17	XP_419999.4
	SNX17	XP_001089913.2
Rattus norvegicus (Norway rat)	Snx17	NP_001011981.1
Danio rerio (zebrafish)	snx17	NP_001038622.2
Drosophila melanogaster (fruit fly)	CG5734	NP_609353.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011491	XP_317811.4
Xenopus tropicalis (tropical clawed frog)	snx17	NP_998873.1

Gene Ontology
Bibliography

Related articles in PubMed

Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling.
McNally KE, Faulkner R, Steinberg F, Gallon M, Ghai R, Pim D, Langton P, Pearson N, Danson CM, N?gele H, Morris LL, Singla A, Overlee BL, Heesom KJ, Sessions R, Banks L, Collins BM, Berger I, Billadeau DD, Burstein E, Cullen PJ
Nature cell biology19(10)1214-1225(2017 Oct)

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Li Y, Klena NT, Gabriel GC, Liu X, Kim AJ, Lemke K, Chen Y, Chatterjee B, Devine W, Damerla RR, Chang C, Yagi H, San Agustin JT, Thahir M, Anderton S, Lawhead C, Vescovi A, Pratt H, Morgan J, Haynes L, Smith CL, Eppig JT, Reinholdt L, Francis R, Leatherbury L, Ganapathiraju MK, Tobita K, Pazour GJ, Lo CW
Nature521(7553)520-4(2015 May)

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Ghai R, Bugarcic A, Liu H, Norwood SJ, Skeldal S, Coulson EJ, Li SS, Teasdale RD, Collins BM
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)

Sorting nexin 17, a non-self-assembling and a PtdIns(3)P high class affinity protein, interacts with the cerebral cavernous malformation related protein KRIT1.
Czubayko M, Knauth P, Schl?ter T, Florian V, Bohnensack R
Biochemical and biophysical research communications345(3)1264-72(2006 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Snx17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Snx17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01846	NM_001011981.1 Latest version!	Rattus norvegicus sorting nexin 17 (Snx17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Snx17 ( NM_001011981.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001011981.1 Rattus norvegicus sorting nexin 17 (Snx17), mRNA.

Price & Availability↑

CloneID	ORa01846
Clone ID Related Accession (Same CDS sequence)	NM_001011981.1
Accession Version	NM_001011981.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1413bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	sorting nexin-17
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC078931.1. On Feb 11, 2005 this sequence version replaced XM_216651.2. ##Evidence-Data-START## Transcript exon combination :: BC078931.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCACTTTT CCATTCCTGA AACCGAGTCC CGCAGCGGGG ACAGCGGCGG CTCCACCTAC 
GTGGCCTATA ACATTCACGT GAATGGAGTC CTGCACTGTC GTGTGCGCTA CAGCCAGCTC 
CTGGGGCTGC ACGAGCAGCT TCGGAAGGAG TATGGGGCCA ATGTGCTTCC TGCATTCCCC 
CCAAAGAAGC TTTTCTCTTT GACGCCTGCA GAGGTAGAAC AGAGGAGGGA ACAGTTAGAG 
AAGTACATGC AAGCTGTTCG GCAAGATCCA TTGCTTGGGA GCAGTGAGAC CTTTAATAGC 
TTTCTACGTC GGGCCCAACA GGAGACACAA CAGGTCCCCA CAGAGGAGGT TTCCTTGGAA 
GTGTTGCTCA GTGACGGACA GAAAGTTCTG GTCAATGTGC TAACTTCTGA CCAGACGGAA 
GACGTCCTGG AGGCCGTGGC TGCAAAGCTG GATCTTCCAG ATGACTTGAT CGGATATTTT 
AGTCTCTTCC TTGTTCGAGA AAAAGAAGAT GGCGCCTTTT CTTTTGTACG GAAGCTTCAG 
GAGTTTGAGC TGCCTTACGT ATCTGTCACC AGTCTTCGGA GTCAAGAGTA TAAGATCGTG 
CTCAGAAAGA GTTACTGGGA CTCTGCCTAT GACGACGATG TCATGGAGAA CCGGGTTGGC 
CTGAACCTGC TTTATGCCCA GACGGTGTCA GACATCGAGC ATGGCTGGAT CCTGGTCACC 
AAGGAGCAGC ACCGACAGCT CAAATCTCTG CAAGAGAAGG TCTCCAAAAA GGAGTTCTTG 
CGGCTGGCCC AGACTCTGCG GCACTATGGC TATCTGCGCT TTGATGCCTG TGTGGCTGAC 
TTTCCGGAGA AGGACTGCCC TGTTGTGGTC AGTGCAGGCA ACAGTGAGCT CAGTCTCCAG 
CTGCGACTCC CAGGCCAGCA GCTCCGTGAA GGCTCTTTCC GGGTCACCCG AATGCGGTGC 
TGGCGGGTCA CCTCCTCTGT GCCACTCCCC AGTGGGGGTA CAAGCACTCC AAGCCGGGGT 
CGGGGTGAGG TACGCCTGGA ACTGGCTTTT GAATACCTCA TGAGCAAGGA CCGGCTACAG 
TGGGTCACCA TCACCAGCCC ACAGGCTATC ATGATGAGCA TCTGCCTGCA GTCCATGGTA 
GATGAGCTGA TGGTGAAGAA GTCTGGGGGC AGTATCAGGA AGATGCTGCG TCGGAGGGTG 
GGGGGCAACC TGAGACGTTC AGACAGCCAG CAAGCAGTGA AGTCCCCACC ATTGCTCGAA 
TCACCAGATG CCAGCCGGGA ATCCATGGTC AAACTCTCAA GTAAACTGAG TGCGGTGAGC 
TTGCGGGGAA TTGGCAGTCC CAGCACAGAT GCCAGTGCCA GTGCCGTCCA CGGCAATTTC 
GCCTTCGAGG GCATTGGAGA TGAGGATCTG TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001011981.1
CDS	106..1518
Translation	MHFSIPETESRSGDSGGSTYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVLPAFPPKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLEVLLSDGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQEFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIEHGWILVTKEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQLRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGGTSTPSRGRGEVRLELAFEYLMSKDRLQWVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGNLRRSDSQQAVKSPPLLESPDASRESMVKLSSKLSAVSLRGIGSPSTDASASAVHGNFAFEGIGDEDL

Target ORF information:

RefSeq Version	NM_001011981.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sorting nexin 17 (Snx17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001011981.1

ORF Insert Sequence:

ATGCACTTTT CCATTCCTGA AACCGAGTCC CGCAGCGGGG ACAGCGGCGG CTCCACCTAC 
GTGGCCTATA ACATTCACGT GAATGGAGTC CTGCACTGTC GTGTGCGCTA CAGCCAGCTC 
CTGGGGCTGC ACGAGCAGCT TCGGAAGGAG TATGGGGCCA ATGTGCTTCC TGCATTCCCC 
CCAAAGAAGC TTTTCTCTTT GACGCCTGCA GAGGTAGAAC AGAGGAGGGA ACAGTTAGAG 
AAGTACATGC AAGCTGTTCG GCAAGATCCA TTGCTTGGGA GCAGTGAGAC CTTTAATAGC 
TTTCTACGTC GGGCCCAACA GGAGACACAA CAGGTCCCCA CAGAGGAGGT TTCCTTGGAA 
GTGTTGCTCA GTGACGGACA GAAAGTTCTG GTCAATGTGC TAACTTCTGA CCAGACGGAA 
GACGTCCTGG AGGCCGTGGC TGCAAAGCTG GATCTTCCAG ATGACTTGAT CGGATATTTT 
AGTCTCTTCC TTGTTCGAGA AAAAGAAGAT GGCGCCTTTT CTTTTGTACG GAAGCTTCAG 
GAGTTTGAGC TGCCTTACGT ATCTGTCACC AGTCTTCGGA GTCAAGAGTA TAAGATCGTG 
CTCAGAAAGA GTTACTGGGA CTCTGCCTAT GACGACGATG TCATGGAGAA CCGGGTTGGC 
CTGAACCTGC TTTATGCCCA GACGGTGTCA GACATCGAGC ATGGCTGGAT CCTGGTCACC 
AAGGAGCAGC ACCGACAGCT CAAATCTCTG CAAGAGAAGG TCTCCAAAAA GGAGTTCTTG 
CGGCTGGCCC AGACTCTGCG GCACTATGGC TATCTGCGCT TTGATGCCTG TGTGGCTGAC 
TTTCCGGAGA AGGACTGCCC TGTTGTGGTC AGTGCAGGCA ACAGTGAGCT CAGTCTCCAG 
CTGCGACTCC CAGGCCAGCA GCTCCGTGAA GGCTCTTTCC GGGTCACCCG AATGCGGTGC 
TGGCGGGTCA CCTCCTCTGT GCCACTCCCC AGTGGGGGTA CAAGCACTCC AAGCCGGGGT 
CGGGGTGAGG TACGCCTGGA ACTGGCTTTT GAATACCTCA TGAGCAAGGA CCGGCTACAG 
TGGGTCACCA TCACCAGCCC ACAGGCTATC ATGATGAGCA TCTGCCTGCA GTCCATGGTA 
GATGAGCTGA TGGTGAAGAA GTCTGGGGGC AGTATCAGGA AGATGCTGCG TCGGAGGGTG 
GGGGGCAACC TGAGACGTTC AGACAGCCAG CAAGCAGTGA AGTCCCCACC ATTGCTCGAA 
TCACCAGATG CCAGCCGGGA ATCCATGGTC AAACTCTCAA GTAAACTGAG TGCGGTGAGC 
TTGCGGGGAA TTGGCAGTCC CAGCACAGAT GCCAGTGCCA GTGCCGTCCA CGGCAATTTC 
GCCTTCGAGG GCATTGGAGA TGAGGATCTG TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling.
Nature cell biology19(10)1214-1225(2017 Oct)
McNally KE,Faulkner R,Steinberg F,Gallon M,Ghai R,Pim D,Langton P,Pearson N,Danson CM,N?gele H,Morris LL,Singla A,Overlee BL,Heesom KJ,Sessions R,Banks L,Collins BM,Berger I,Billadeau DD,Burstein E,Cullen PJ

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Nature521(7553)520-4(2015 May)
Li Y,Klena NT,Gabriel GC,Liu X,Kim AJ,Lemke K,Chen Y,Chatterjee B,Devine W,Damerla RR,Chang C,Yagi H,San Agustin JT,Thahir M,Anderton S,Lawhead C,Vescovi A,Pratt H,Morgan J,Haynes L,Smith CL,Eppig JT,Reinholdt L,Francis R,Leatherbury L,Ganapathiraju MK,Tobita K,Pazour GJ,Lo CW

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)
Ghai R,Bugarcic A,Liu H,Norwood SJ,Skeldal S,Coulson EJ,Li SS,Teasdale RD,Collins BM

Sorting nexin 17, a non-self-assembling and a PtdIns(3)P high class affinity protein, interacts with the cerebral cavernous malformation related protein KRIT1.
Biochemical and biophysical research communications345(3)1264-72(2006 Jul)
Czubayko M,Knauth P,Schl?ter T,Florian V,Bohnensack R

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Snx17 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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