Zfp36l2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Zfp36l2
Entrez Gene ID	298765
Full Name	zinc finger protein 36, C3H type-like 2
General protein information	Preferred Names zinc finger protein 36, C3H type-like 2 Names zinc finger protein 36, C3H1 type-like 2 butyrate response factor 2 zinc finger protein 36, C3H type-like 2-like
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001036626.1	NP_001031703.1	zinc finger protein 36, C3H1 type-like 2
XM_017603180.1	XP_017458669.1	zinc finger protein 36, C3H1 type-like 2 isoform X2
XM_008764455.2	XP_008762677.1	zinc finger protein 36, C3H1 type-like 2 isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Zfp36l2	NP_001001806.1
Homo sapiens (human)	ZFP36L2	NP_008818.3
Canis lupus familiaris (dog)	ZFP36L2	XP_003639394.1
Xenopus tropicalis (tropical clawed frog)	zfp36l2	NP_001096423.1
	LOC716319	XP_001106984.2
Pan troglodytes (chimpanzee)	ZFP36L2	XP_515435.2
Bos taurus (cattle)	ZFP36L2	NP_001178120.1
Rattus norvegicus (Norway rat)	Zfp36l2	NP_001031703.1
Rattus norvegicus (Norway rat)	LOC100911319	XP_003750309.1
Danio rerio (zebrafish)	zfp36l2	NP_996938.1

Gene Ontology
Bibliography

Related articles in PubMed

Functional analysis of ZFP36 proteins in keratinocytes.
Prenzler F, Fragasso A, Schmitt A, Munz B
European journal of cell biology95(8)277-84(2016 Aug)

RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence.
Galloway A, Saveliev A, ?ukasiak S, Hodson DJ, Bolland D, Balmanno K, Ahlfors H, Monz?n-Casanova E, Mannurita SC, Bell LS, Andrews S, D?az-Mu?oz MD, Cook SJ, Corcoran A, Turner M
Science (New York, N.Y.)352(6284)453-9(2016 Apr)

ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway.
Adachi S, Homoto M, Tanaka R, Hioki Y, Murakami H, Suga H, Matsumoto M, Nakayama KI, Hatta T, Iemura S, Natsume T
Nucleic acids research42(15)10037-49(2014 Sep)

Brf1 posttranscriptionally regulates pluripotency and differentiation responses downstream of Erk MAP kinase.
Tan FE, Elowitz MB
Proceedings of the National Academy of Sciences of the United States of America111(17)E1740-8(2014 Apr)

ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors.
Zhang L, Prak L, Rayon-Estrada V, Thiru P, Flygare J, Lim B, Lodish HF
Nature499(7456)92-6(2013 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Zfp36l2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Zfp36l2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa55605	XM_017603180.1 Latest version!	Rattus norvegicus zinc finger protein 36, C3H type-like 2 (Zfp36l2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa09210	NM_001036626.1 Latest version!	Rattus norvegicus zinc finger protein 36, C3H type-like 2 (Zfp36l2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$286.30 $409.00
ORa45568	XM_008764455.2 Latest version!	Rattus norvegicus zinc finger protein 36, C3H type-like 2 (Zfp36l2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Zfp36l2 ( XM_017603180.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017458669.1 Rattus norvegicus zinc finger protein 36, C3H type-like 2 (Zfp36l2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa55605
Clone ID Related Accession (Same CDS sequence)	XM_017603180.1
Accession Version	XM_017603180.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1011bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	zinc finger protein 36, C3H1 type-like 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (AC_000074.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGACCA CTCTTCTGTC AGCTTTCTAC GATATCGACT TCTTGTGCAA GACGGAGAAA 
TCCCTGGCAA ACCTCAATCT GAACAACATG CTGGACAAGA AGGCGGTGGG GACGCCCGTG 
GCTGCTGCCC CCAGCTCGAG CTTCACTCCG GGGTTCCTGA GACGCCACTC CGCCAGCAAC 
CTACACGCGC TCGCCCACCC CAGTCCTGGC AGCTGCTCGC CTAAGTTCCC AGGCGCCCCT 
AACGGCAGCA GCTGTGGCCC GGCAGGCGCG GGCGGCCCGT CCTCCTACGG CCAGCTCAAG 
GAGCCTTCAG GGGGCAGCGG CACGGCGCTG GTCAACAAGG AAAGCAAATT CCGGGATCGC 
TCTTTCAGCG AGAACGGTGA GCGCAGCCAG CACCTCCTGC ACCTGCAGCA GCAGCAGAAG 
GGGGGCAGCG GCTCCCAAAT CAACTCCACG CGCTACAAGA CCGAGCTGTG CCGGCCCTTC 
GAGGAGAGCG GCACGTGCAA GTACGGCGAG AAGTGCCAGT TCGCGCACGG CTTCCATGAG 
CTGCGCAGCC TCACTCGGCA CCCCAAGTAC AAGACGGAGC TGTGCCGCAC CTTCCACACC 
ATCGGCTTCT GCCCCTACGG CCCGCGCTGC CATTTCATCC ACAACGCAGA CGAGCGGCGG 
CCCGCACCAT CGGGGGGCGC CTCCGGGGAC CTGCGAGCGT TTGGCGCGCG CGACGCGCTG 
CACCTGGGCT TTGCCCGGGA GCCGCGGCCA AAGCTGCACC ACAGCCTCAG TTTCTCCGGC 
TTCCCGTCGG GCCACCACCA GCCGCCCGGG GGACTGGAGT CGCCGCTGCT GCTCGACAGC 
CCCACGTCGC GCACGCCGCC GCCGCCCTCC TGTTCCTCCG CCTCGTCCTG TTCCTCATCA 
GCCTCTTCCT GCTACTATAC GCAAGGTCCC CATGGAGAAG GGTTAAATGT ATATATAGCC 
CATAGTTTCA TGGCCATGGT TGTGCAAGTG GCTGGCAGCC CCAGTGGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017458669.1
CDS	2244..3254
Translation	MSTTLLSAFYDIDFLCKTEKSLANLNLNNMLDKKAVGTPVAAAPSSSFTPGFLRRHSASNLHALAHPSPGSCSPKFPGAPNGSSCGPAGAGGPSSYGQLKEPSGGSGTALVNKESKFRDRSFSENGERSQHLLHLQQQQKGGSGSQINSTRYKTELCRPFEESGTCKYGEKCQFAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGGASGDLRAFGARDALHLGFAREPRPKLHHSLSFSGFPSGHHQPPGGLESPLLLDSPTSRTPPPPSCSSASSCSSSASSCYYTQGPHGEGLNVYIAHSFMAMVVQVAGSPSG

Target ORF information:

RefSeq Version	XM_017603180.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus zinc finger protein 36, C3H type-like 2 (Zfp36l2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017603180.1

ORF Insert Sequence:

ATGTCGACCA CTCTTCTGTC AGCTTTCTAC GATATCGACT TCTTGTGCAA GACGGAGAAA 
TCCCTGGCAA ACCTCAATCT GAACAACATG CTGGACAAGA AGGCGGTGGG GACGCCCGTG 
GCTGCTGCCC CCAGCTCGAG CTTCACTCCG GGGTTCCTGA GACGCCACTC CGCCAGCAAC 
CTACACGCGC TCGCCCACCC CAGTCCTGGC AGCTGCTCGC CTAAGTTCCC AGGCGCCCCT 
AACGGCAGCA GCTGTGGCCC GGCAGGCGCG GGCGGCCCGT CCTCCTACGG CCAGCTCAAG 
GAGCCTTCAG GGGGCAGCGG CACGGCGCTG GTCAACAAGG AAAGCAAATT CCGGGATCGC 
TCTTTCAGCG AGAACGGTGA GCGCAGCCAG CACCTCCTGC ACCTGCAGCA GCAGCAGAAG 
GGGGGCAGCG GCTCCCAAAT CAACTCCACG CGCTACAAGA CCGAGCTGTG CCGGCCCTTC 
GAGGAGAGCG GCACGTGCAA GTACGGCGAG AAGTGCCAGT TCGCGCACGG CTTCCATGAG 
CTGCGCAGCC TCACTCGGCA CCCCAAGTAC AAGACGGAGC TGTGCCGCAC CTTCCACACC 
ATCGGCTTCT GCCCCTACGG CCCGCGCTGC CATTTCATCC ACAACGCAGA CGAGCGGCGG 
CCCGCACCAT CGGGGGGCGC CTCCGGGGAC CTGCGAGCGT TTGGCGCGCG CGACGCGCTG 
CACCTGGGCT TTGCCCGGGA GCCGCGGCCA AAGCTGCACC ACAGCCTCAG TTTCTCCGGC 
TTCCCGTCGG GCCACCACCA GCCGCCCGGG GGACTGGAGT CGCCGCTGCT GCTCGACAGC 
CCCACGTCGC GCACGCCGCC GCCGCCCTCC TGTTCCTCCG CCTCGTCCTG TTCCTCATCA 
GCCTCTTCCT GCTACTATAC GCAAGGTCCC CATGGAGAAG GGTTAAATGT ATATATAGCC 
CATAGTTTCA TGGCCATGGT TGTGCAAGTG GCTGGCAGCC CCAGTGGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Zfp36l2 ( NM_001036626.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001031703.1 Rattus norvegicus zinc finger protein 36, C3H type-like 2 (Zfp36l2), mRNA.

Price & Availability↑

CloneID	ORa09210
Clone ID Related Accession (Same CDS sequence)	NM_001036626.1
Accession Version	NM_001036626.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1449bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-31
Organism	Rattus norvegicus(Norway rat)
Product	zinc finger protein 36, C3H1 type-like 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR07062776.1. On Nov 5, 2005 this sequence version replaced XM_238444.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CV112816.1, EV769376.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297, SAMN01906348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGACCA CTCTTCTGTC AGCTTTCTAC GATATCGACT TCTTGTGCAA GACGGAGAAA 
TCCCTGGCAA ACCTCAATCT GAACAACATG CTGGACAAGA AGGCGGTGGG GACGCCCGTG 
GCTGCTGCCC CCAGCTCGAG CTTCACTCCG GGGTTCCTGA GACGCCACTC CGCCAGCAAC 
CTACACGCGC TCGCCCACCC CAGTCCTGGC AGCTGCTCGC CTAAGTTCCC AGGCGCCCCT 
AACGGCAGCA GCTGTGGCCC GGCAGGCGCG GGCGGCCCGT CCTCCTACGG CCAGCTCAAG 
GAGCCTTCAG GGGGCAGCGG CACGGCGCTG GTCAACAAGG AAAGCAAATT CCGGGATCGC 
TCTTTCAGCG AGAACGGTGA GCGCAGCCAG CACCTCCTGC ACCTGCAGCA GCAGCAGAAG 
GGGGGCAGCG GCTCCCAAAT CAACTCCACG CGCTACAAGA CCGAGCTGTG CCGGCCCTTC 
GAGGAGAGCG GCACGTGCAA GTACGGCGAG AAGTGCCAGT TCGCGCACGG CTTCCATGAG 
CTGCGCAGCC TCACTCGGCA CCCCAAGTAC AAGACGGAGC TGTGCCGCAC CTTCCACACC 
ATCGGCTTCT GCCCCTACGG CCCGCGCTGC CATTTCATCC ACAACGCAGA CGAGCGGCGG 
CCCGCACCAT CGGGGGGCGC CTCCGGGGAC CTGCGAGCGT TTGGCGCGCG CGACGCGCTG 
CACCTGGGCT TTGCCCGGGA GCCGCGGCCA AAGCTGCACC ACAGCCTCAG TTTCTCCGGC 
TTCCCGTCGG GCCACCACCA GCCGCCCGGG GGACTGGAGT CGCCGCTGCT GCTCGACAGC 
CCCACGTCGC GCACGCCGCC GCCGCCCTCC TGTTCCTCCG CCTCGTCCTG TTCCTCATCA 
GCCTCTTCCT GCTCCTCCAC CTCAGCGGCC TCCACACCCT CGGGCGCCCC GACGTGCTGT 
GCCTCAGCGG CGGCGGCGGC GGCGGCCGCG CTGCTCTACG GCCCCGGAGG CGCGGAGGAC 
CTGCTGACTC CCGGAGCGCC GTGCGCCACT TGCTCGACCA CCTCGTGCGC CAACAACGCC 
TTCACCTTCG GCCCGGAGGT GAGCAGCCTC ATCACGCCAC TTGCCATCCA GACCCACAAC 
TTCGCCGCCG CGGCCGCCGC CTACTACCGC AGCCAGCAGC AGGGCCTGGC GGGCCTCGCG 
CCGGCCCCTG CGCAGCCCCC CGCGGCCCCC GCGCCGCCCT CGCCGCCCTT CGGCTTCCAG 
CTGCCGCGCC GTCTGTCCGA GTCGCCGGTG TTCGACGCGC CCCCCAGCCC CCCGGACTCG 
CTGTCGGACC GCGACAGTTA CCTGAGTGGC TCGCTGAGCT CGGGCAGCCT CAGCGGCTCC 
GAGTCCCCCA GCCTGGACCC CGGCCGCCGC CTGCCCATCT TCAGCCGCCT CTCCATCTCC 
GACGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001031703.1
CDS	234..1682
Translation	MSTTLLSAFYDIDFLCKTEKSLANLNLNNMLDKKAVGTPVAAAPSSSFTPGFLRRHSASNLHALAHPSPGSCSPKFPGAPNGSSCGPAGAGGPSSYGQLKEPSGGSGTALVNKESKFRDRSFSENGERSQHLLHLQQQQKGGSGSQINSTRYKTELCRPFEESGTCKYGEKCQFAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGGASGDLRAFGARDALHLGFAREPRPKLHHSLSFSGFPSGHHQPPGGLESPLLLDSPTSRTPPPPSCSSASSCSSSASSCSSTSAASTPSGAPTCCASAAAAAAAALLYGPGGAEDLLTPGAPCATCSTTSCANNAFTFGPEVSSLITPLAIQTHNFAAAAAAYYRSQQQGLAGLAPAPAQPPAAPAPPSPPFGFQLPRRLSESPVFDAPPSPPDSLSDRDSYLSGSLSSGSLSGSESPSLDPGRRLPIFSRLSISDD

Target ORF information:

RefSeq Version	NM_001036626.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus zinc finger protein 36, C3H type-like 2 (Zfp36l2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001036626.1

ORF Insert Sequence:

ATGTCGACCA CTCTTCTGTC AGCTTTCTAC GATATCGACT TCTTGTGCAA GACGGAGAAA 
TCCCTGGCAA ACCTCAATCT GAACAACATG CTGGACAAGA AGGCGGTGGG GACGCCCGTG 
GCTGCTGCCC CCAGCTCGAG CTTCACTCCG GGGTTCCTGA GACGCCACTC CGCCAGCAAC 
CTACACGCGC TCGCCCACCC CAGTCCTGGC AGCTGCTCGC CTAAGTTCCC AGGCGCCCCT 
AACGGCAGCA GCTGTGGCCC GGCAGGCGCG GGCGGCCCGT CCTCCTACGG CCAGCTCAAG 
GAGCCTTCAG GGGGCAGCGG CACGGCGCTG GTCAACAAGG AAAGCAAATT CCGGGATCGC 
TCTTTCAGCG AGAACGGTGA GCGCAGCCAG CACCTCCTGC ACCTGCAGCA GCAGCAGAAG 
GGGGGCAGCG GCTCCCAAAT CAACTCCACG CGCTACAAGA CCGAGCTGTG CCGGCCCTTC 
GAGGAGAGCG GCACGTGCAA GTACGGCGAG AAGTGCCAGT TCGCGCACGG CTTCCATGAG 
CTGCGCAGCC TCACTCGGCA CCCCAAGTAC AAGACGGAGC TGTGCCGCAC CTTCCACACC 
ATCGGCTTCT GCCCCTACGG CCCGCGCTGC CATTTCATCC ACAACGCAGA CGAGCGGCGG 
CCCGCACCAT CGGGGGGCGC CTCCGGGGAC CTGCGAGCGT TTGGCGCGCG CGACGCGCTG 
CACCTGGGCT TTGCCCGGGA GCCGCGGCCA AAGCTGCACC ACAGCCTCAG TTTCTCCGGC 
TTCCCGTCGG GCCACCACCA GCCGCCCGGG GGACTGGAGT CGCCGCTGCT GCTCGACAGC 
CCCACGTCGC GCACGCCGCC GCCGCCCTCC TGTTCCTCCG CCTCGTCCTG TTCCTCATCA 
GCCTCTTCCT GCTCCTCCAC CTCAGCGGCC TCCACACCCT CGGGCGCCCC GACGTGCTGT 
GCCTCAGCGG CGGCGGCGGC GGCGGCCGCG CTGCTCTACG GCCCCGGAGG CGCGGAGGAC 
CTGCTGACTC CCGGAGCGCC GTGCGCCACT TGCTCGACCA CCTCGTGCGC CAACAACGCC 
TTCACCTTCG GCCCGGAGGT GAGCAGCCTC ATCACGCCAC TTGCCATCCA GACCCACAAC 
TTCGCCGCCG CGGCCGCCGC CTACTACCGC AGCCAGCAGC AGGGCCTGGC GGGCCTCGCG 
CCGGCCCCTG CGCAGCCCCC CGCGGCCCCC GCGCCGCCCT CGCCGCCCTT CGGCTTCCAG 
CTGCCGCGCC GTCTGTCCGA GTCGCCGGTG TTCGACGCGC CCCCCAGCCC CCCGGACTCG 
CTGTCGGACC GCGACAGTTA CCTGAGTGGC TCGCTGAGCT CGGGCAGCCT CAGCGGCTCC 
GAGTCCCCCA GCCTGGACCC CGGCCGCCGC CTGCCCATCT TCAGCCGCCT CTCCATCTCC 
GACGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Zfp36l2 ( XM_008764455.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008762677.1 Rattus norvegicus zinc finger protein 36, C3H type-like 2 (Zfp36l2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa45568
Clone ID Related Accession (Same CDS sequence)	XM_008764455.2
Accession Version	XM_008764455.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1485bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	zinc finger protein 36, C3H1 type-like 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008764455.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGACCA CTCTTCTGTC AGCTTTCTAC GATATCGACT TCTTGTGCAA GATTTTCATC 
CCGTCCCCGG TCCCCTCCCT TTGGCAGACG GAGAAATCCC TGGCAAACCT CAATCTGAAC 
AACATGCTGG ACAAGAAGGC GGTGGGGACG CCCGTGGCTG CTGCCCCCAG CTCGAGCTTC 
ACTCCGGGGT TCCTGAGACG CCACTCCGCC AGCAACCTAC ACGCGCTCGC CCACCCCAGT 
CCTGGCAGCT GCTCGCCTAA GTTCCCAGGC GCCCCTAACG GCAGCAGCTG TGGCCCGGCA 
GGCGCGGGCG GCCCGTCCTC CTACGGCCAG CTCAAGGAGC CTTCAGGGGG CAGCGGCACG 
GCGCTGGTCA ACAAGGAAAG CAAATTCCGG GATCGCTCTT TCAGCGAGAA CGGTGAGCGC 
AGCCAGCACC TCCTGCACCT GCAGCAGCAG CAGAAGGGGG GCAGCGGCTC CCAAATCAAC 
TCCACGCGCT ACAAGACCGA GCTGTGCCGG CCCTTCGAGG AGAGCGGCAC GTGCAAGTAC 
GGCGAGAAGT GCCAGTTCGC GCACGGCTTC CATGAGCTGC GCAGCCTCAC TCGGCACCCC 
AAGTACAAGA CGGAGCTGTG CCGCACCTTC CACACCATCG GCTTCTGCCC CTACGGCCCG 
CGCTGCCATT TCATCCACAA CGCAGACGAG CGGCGGCCCG CACCATCGGG GGGCGCCTCC 
GGGGACCTGC GAGCGTTTGG CGCGCGCGAC GCGCTGCACC TGGGCTTTGC CCGGGAGCCG 
CGGCCAAAGC TGCACCACAG CCTCAGTTTC TCCGGCTTCC CGTCGGGCCA CCACCAGCCG 
CCCGGGGGAC TGGAGTCGCC GCTGCTGCTC GACAGCCCCA CGTCGCGCAC GCCGCCGCCG 
CCCTCCTGTT CCTCCGCCTC GTCCTGTTCC TCATCAGCCT CTTCCTGCTC CTCCACCTCA 
GCGGCCTCCA CACCCTCGGG CGCCCCGACG TGCTGTGCCT CAGCGGCGGC GGCGGCGGCG 
GCCGCGCTGC TCTACGGCCC CGGAGGCGCG GAGGACCTGC TGACTCCCGG AGCGCCGTGC 
GCCACTTGCT CGACCACCTC GTGCGCCAAC AACGCCTTCA CCTTCGGCCC GGAGGTGAGC 
AGCCTCATCA CGCCACTTGC CATCCAGACC CACAACTTCG CCGCCGCGGC CGCCGCCTAC 
TACCGCAGCC AGCAGCAGGG CCTGGCGGGC CTCGCGCCGG CCCCTGCGCA GCCCCCCGCG 
GCCCCCGCGC CGCCCTCGCC GCCCTTCGGC TTCCAGCTGC CGCGCCGTCT GTCCGAGTCG 
CCGGTGTTCG ACGCGCCCCC CAGCCCCCCG GACTCGCTGT CGGACCGCGA CAGTTACCTG 
AGTGGCTCGC TGAGCTCGGG CAGCCTCAGC GGCTCCGAGT CCCCCAGCCT GGACCCCGGC 
CGCCGCCTGC CCATCTTCAG CCGCCTCTCC ATCTCCGACG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008762677.1
CDS	2225..3709
Translation	MSTTLLSAFYDIDFLCKIFIPSPVPSLWQTEKSLANLNLNNMLDKKAVGTPVAAAPSSSFTPGFLRRHSASNLHALAHPSPGSCSPKFPGAPNGSSCGPAGAGGPSSYGQLKEPSGGSGTALVNKESKFRDRSFSENGERSQHLLHLQQQQKGGSGSQINSTRYKTELCRPFEESGTCKYGEKCQFAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGGASGDLRAFGARDALHLGFAREPRPKLHHSLSFSGFPSGHHQPPGGLESPLLLDSPTSRTPPPPSCSSASSCSSSASSCSSTSAASTPSGAPTCCASAAAAAAAALLYGPGGAEDLLTPGAPCATCSTTSCANNAFTFGPEVSSLITPLAIQTHNFAAAAAAYYRSQQQGLAGLAPAPAQPPAAPAPPSPPFGFQLPRRLSESPVFDAPPSPPDSLSDRDSYLSGSLSSGSLSGSESPSLDPGRRLPIFSRLSISDD

Target ORF information:

RefSeq Version	XM_008764455.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus zinc finger protein 36, C3H type-like 2 (Zfp36l2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008764455.2

ORF Insert Sequence:

ATGTCGACCA CTCTTCTGTC AGCTTTCTAC GATATCGACT TCTTGTGCAA GATTTTCATC 
CCGTCCCCGG TCCCCTCCCT TTGGCAGACG GAGAAATCCC TGGCAAACCT CAATCTGAAC 
AACATGCTGG ACAAGAAGGC GGTGGGGACG CCCGTGGCTG CTGCCCCCAG CTCGAGCTTC 
ACTCCGGGGT TCCTGAGACG CCACTCCGCC AGCAACCTAC ACGCGCTCGC CCACCCCAGT 
CCTGGCAGCT GCTCGCCTAA GTTCCCAGGC GCCCCTAACG GCAGCAGCTG TGGCCCGGCA 
GGCGCGGGCG GCCCGTCCTC CTACGGCCAG CTCAAGGAGC CTTCAGGGGG CAGCGGCACG 
GCGCTGGTCA ACAAGGAAAG CAAATTCCGG GATCGCTCTT TCAGCGAGAA CGGTGAGCGC 
AGCCAGCACC TCCTGCACCT GCAGCAGCAG CAGAAGGGGG GCAGCGGCTC CCAAATCAAC 
TCCACGCGCT ACAAGACCGA GCTGTGCCGG CCCTTCGAGG AGAGCGGCAC GTGCAAGTAC 
GGCGAGAAGT GCCAGTTCGC GCACGGCTTC CATGAGCTGC GCAGCCTCAC TCGGCACCCC 
AAGTACAAGA CGGAGCTGTG CCGCACCTTC CACACCATCG GCTTCTGCCC CTACGGCCCG 
CGCTGCCATT TCATCCACAA CGCAGACGAG CGGCGGCCCG CACCATCGGG GGGCGCCTCC 
GGGGACCTGC GAGCGTTTGG CGCGCGCGAC GCGCTGCACC TGGGCTTTGC CCGGGAGCCG 
CGGCCAAAGC TGCACCACAG CCTCAGTTTC TCCGGCTTCC CGTCGGGCCA CCACCAGCCG 
CCCGGGGGAC TGGAGTCGCC GCTGCTGCTC GACAGCCCCA CGTCGCGCAC GCCGCCGCCG 
CCCTCCTGTT CCTCCGCCTC GTCCTGTTCC TCATCAGCCT CTTCCTGCTC CTCCACCTCA 
GCGGCCTCCA CACCCTCGGG CGCCCCGACG TGCTGTGCCT CAGCGGCGGC GGCGGCGGCG 
GCCGCGCTGC TCTACGGCCC CGGAGGCGCG GAGGACCTGC TGACTCCCGG AGCGCCGTGC 
GCCACTTGCT CGACCACCTC GTGCGCCAAC AACGCCTTCA CCTTCGGCCC GGAGGTGAGC 
AGCCTCATCA CGCCACTTGC CATCCAGACC CACAACTTCG CCGCCGCGGC CGCCGCCTAC 
TACCGCAGCC AGCAGCAGGG CCTGGCGGGC CTCGCGCCGG CCCCTGCGCA GCCCCCCGCG 
GCCCCCGCGC CGCCCTCGCC GCCCTTCGGC TTCCAGCTGC CGCGCCGTCT GTCCGAGTCG 
CCGGTGTTCG ACGCGCCCCC CAGCCCCCCG GACTCGCTGT CGGACCGCGA CAGTTACCTG 
AGTGGCTCGC TGAGCTCGGG CAGCCTCAGC GGCTCCGAGT CCCCCAGCCT GGACCCCGGC 
CGCCGCCTGC CCATCTTCAG CCGCCTCTCC ATCTCCGACG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Functional analysis of ZFP36 proteins in keratinocytes.
European journal of cell biology95(8)277-84(2016 Aug)
Prenzler F,Fragasso A,Schmitt A,Munz B

RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence.
Science (New York, N.Y.)352(6284)453-9(2016 Apr)
Galloway A,Saveliev A,?ukasiak S,Hodson DJ,Bolland D,Balmanno K,Ahlfors H,Monz?n-Casanova E,Mannurita SC,Bell LS,Andrews S,D?az-Mu?oz MD,Cook SJ,Corcoran A,Turner M

ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway.
Nucleic acids research42(15)10037-49(2014 Sep)
Adachi S,Homoto M,Tanaka R,Hioki Y,Murakami H,Suga H,Matsumoto M,Nakayama KI,Hatta T,Iemura S,Natsume T

Brf1 posttranscriptionally regulates pluripotency and differentiation responses downstream of Erk MAP kinase.
Proceedings of the National Academy of Sciences of the United States of America111(17)E1740-8(2014 Apr)
Tan FE,Elowitz MB

ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors.
Nature499(7456)92-6(2013 Jul)
Zhang L,Prak L,Rayon-Estrada V,Thiru P,Flygare J,Lim B,Lodish HF

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Zfp36l2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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