Ca6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ca6
Entrez Gene ID	298657
Full Name	carbonic anhydrase 6
Synonyms	CA6
General protein information	Preferred Names carbonic anhydrase 6 Names carbonic anhydrase 6 carbonic anhydrase VI gustin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36
Summary	enzyme that converts bicarbonate to water and CO(2); component of mammalian saliva and milk [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001134841.1	NP_001128313.1	carbonic anhydrase 6 precursor

Pathways from BioSystems

Homologies

	LOC709540	XP_001099188.2
Bos taurus (cattle)	CA6	NP_776323.1
Gallus gallus (chicken)	CA6	XP_425745.4
Mus musculus (house mouse)	Car6	NP_033932.2
Homo sapiens (human)	CA6	NP_001206.2
Pan troglodytes (chimpanzee)	CA6	XP_003307839.2
Canis lupus familiaris (dog)	CA6	NP_001002999.1
Rattus norvegicus (Norway rat)	Car6	NP_001128313.1
Danio rerio (zebrafish)	LOC100006448	XP_002666525.1

Gene Ontology
Bibliography

Related articles in PubMed

Salivary protein profiles are linked to bitter taste acceptance in infants.
Morzel M, Chabanet C, Schwartz C, Lucchi G, Ducoroy P, Nicklaus S
European journal of pediatrics173(5)575-82(2014 May)

Expression patterns and subcellular localization of carbonic anhydrases are developmentally regulated during tooth formation.
Reibring CG, El Shahawy M, Hallberg K, Kannius-Janson M, Nilsson J, Parkkila S, Sly WS, Waheed A, Linde A, Gritli-Linde A
PloS one9(5)e96007(2014)

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal of proteome research8(3)1304-14(2009 Mar)

Evidence by signal peptide trap technology for the expression of carbonic anhydrase 6 in rat incisor enamel organs.
Smith CE, Nanci A, Moffatt P
European journal of oral sciences114 Suppl 1147-53; discussion 164-5, 380-1(2006 May)

Identification of secreted and membrane proteins in the rat incisor enamel organ using a signal-trap screening approach.
Moffatt P, Smith CE, Sooknanan R, St-Arnaud R, Nanci A
European journal of oral sciences114 Suppl 1139-46; discussion 164-5, 380-1(2006 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ca6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ca6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03646	NM_001134841.1 Latest version!	Rattus norvegicus carbonic anhydrase 6 (Ca6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ca6 ( NM_001134841.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001128313.1 Rattus norvegicus carbonic anhydrase 6 (Ca6), mRNA.

Price & Availability↑

CloneID	ORa03646
Clone ID Related Accession (Same CDS sequence)	NM_001134841.1
Accession Version	NM_001134841.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-22
Organism	Rattus norvegicus(Norway rat)
Product	carbonic anhydrase 6 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR07050496.1. On Sep 9, 2008 this sequence version replaced XM_216584.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689602 [ECO:0000348] ##Evidence-Data-END##

ATGAGGGTTC TGGTGAGCGT GGTGTCCTTG TTCTTCCTGG GCATCCAGGC CCTCAGTGAG 
TGGAGCTACT CAGGGGATGA CGGCCTGGAA GAGAGTCGGT GGCCTGAGAA GTACCCTTCC 
TGCGGCGGGG AAAGGCAGTC GCCCATCGAT GTGAAGAGGA GGGAGGTGCA CTTCAGTAGC 
TCCTTGTTGC CCCTGCACAT GGTCAACTAT GAGGAGGAGG GGCTGGAGCT CTCTATGACT 
AACAACGGAC ACACAGTACA GATCACCCTG CCGAACACCA TGTCCATGAG AGACTCTGAC 
GGCACTGTGT ACAGGACAAA GCAGATGCAC TTTCACTGGG GCGGTCGGGA CTCAGAAATC 
AGTGGCTCTG AGCACACCAT CGATGGGATG AGGCACGCCA TAGAGATTCA CCTTGTTCAC 
TTCAACGAGA AGTACGAGAC CTACGAGAAA GCCGTGGACC AACCAGACGG CTTGGCGGTG 
ATGGCGGTCT TGGTTAAGGT TGAGGATTAC ACAGAAAACG ATTACTACAG CACCTTCATT 
TCTGAGCTGG AAAACGTCAA GTATACAGGA CAAACCACGA CACTGAGAAA CGTTAACATC 
CGGAACATGT TGCCCGGGGA CATCAGACAC TACTACACCT ACCAAGGCTC GCTCACCACT 
CCCCCCTGCA CGGAGAACGT CAAGTGGTTT GTGTTTCAGG ATTCCGCCAC CATCTCCAAG 
GCCCAGGCTG AGAGAATAGA GAATGCGGTA ATGGATCACC ACAACCAGAC CATTCGAAAT 
GGTTACCGCA GGACGCAGCC CCTCCACAAC AGGGTGGTGG AAGCCAATTT CCCATACTCC 
CCGGATGAAG TCTCTAAGAA CCACTTTTAC ATGCACGAGA AGATTTCACA CGGTTTGAAA 
CTAAAGAAAA TTAAGAAGAA GAGAAACCAC AGCCATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001128313.1
CDS	27..965
Translation	MRVLVSVVSLFFLGIQALSEWSYSGDDGLEESRWPEKYPSCGGERQSPIDVKRREVHFSSSLLPLHMVNYEEEGLELSMTNNGHTVQITLPNTMSMRDSDGTVYRTKQMHFHWGGRDSEISGSEHTIDGMRHAIEIHLVHFNEKYETYEKAVDQPDGLAVMAVLVKVEDYTENDYYSTFISELENVKYTGQTTTLRNVNIRNMLPGDIRHYYTYQGSLTTPPCTENVKWFVFQDSATISKAQAERIENAVMDHHNQTIRNGYRRTQPLHNRVVEANFPYSPDEVSKNHFYMHEKISHGLKLKKIKKKRNHSH

Target ORF information:

RefSeq Version	NM_001134841.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus carbonic anhydrase 6 (Ca6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001134841.1

ORF Insert Sequence:

ATGAGGGTTC TGGTGAGCGT GGTGTCCTTG TTCTTCCTGG GCATCCAGGC CCTCAGTGAG 
TGGAGCTACT CAGGGGATGA CGGCCTGGAA GAGAGTCGGT GGCCTGAGAA GTACCCTTCC 
TGCGGCGGGG AAAGGCAGTC GCCCATCGAT GTGAAGAGGA GGGAGGTGCA CTTCAGTAGC 
TCCTTGTTGC CCCTGCACAT GGTCAACTAT GAGGAGGAGG GGCTGGAGCT CTCTATGACT 
AACAACGGAC ACACAGTACA GATCACCCTG CCGAACACCA TGTCCATGAG AGACTCTGAC 
GGCACTGTGT ACAGGACAAA GCAGATGCAC TTTCACTGGG GCGGTCGGGA CTCAGAAATC 
AGTGGCTCTG AGCACACCAT CGATGGGATG AGGCACGCCA TAGAGATTCA CCTTGTTCAC 
TTCAACGAGA AGTACGAGAC CTACGAGAAA GCCGTGGACC AACCAGACGG CTTGGCGGTG 
ATGGCGGTCT TGGTTAAGGT TGAGGATTAC ACAGAAAACG ATTACTACAG CACCTTCATT 
TCTGAGCTGG AAAACGTCAA GTATACAGGA CAAACCACGA CACTGAGAAA CGTTAACATC 
CGGAACATGT TGCCCGGGGA CATCAGACAC TACTACACCT ACCAAGGCTC GCTCACCACT 
CCCCCCTGCA CGGAGAACGT CAAGTGGTTT GTGTTTCAGG ATTCCGCCAC CATCTCCAAG 
GCCCAGGCTG AGAGAATAGA GAATGCGGTA ATGGATCACC ACAACCAGAC CATTCGAAAT 
GGTTACCGCA GGACGCAGCC CCTCCACAAC AGGGTGGTGG AAGCCAATTT CCCATACTCC 
CCGGATGAAG TCTCTAAGAA CCACTTTTAC ATGCACGAGA AGATTTCACA CGGTTTGAAA 
CTAAAGAAAA TTAAGAAGAA GAGAAACCAC AGCCATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Salivary protein profiles are linked to bitter taste acceptance in infants.
European journal of pediatrics173(5)575-82(2014 May)
Morzel M,Chabanet C,Schwartz C,Lucchi G,Ducoroy P,Nicklaus S

Expression patterns and subcellular localization of carbonic anhydrases are developmentally regulated during tooth formation.
PloS one9(5)e96007(2014)
Reibring CG,El Shahawy M,Hallberg K,Kannius-Janson M,Nilsson J,Parkkila S,Sly WS,Waheed A,Linde A,Gritli-Linde A

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Journal of proteome research8(3)1304-14(2009 Mar)
Gonzalez-Begne M,Lu B,Han X,Hagen FK,Hand AR,Melvin JE,Yates JR

Evidence by signal peptide trap technology for the expression of carbonic anhydrase 6 in rat incisor enamel organs.
European journal of oral sciences114 Suppl 1147-53; discussion 164-5, 380-1(2006 May)
Smith CE,Nanci A,Moffatt P

Identification of secreted and membrane proteins in the rat incisor enamel organ using a signal-trap screening approach.
European journal of oral sciences114 Suppl 1139-46; discussion 164-5, 380-1(2006 May)
Moffatt P,Smith CE,Sooknanan R,St-Arnaud R,Nanci A