Capzb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Capzb
Entrez Gene ID	298584
Full Name	capping actin protein of muscle Z-line beta subunit
General protein information	Preferred Names capping actin protein of muscle Z-line beta subunit Names F-actin-capping protein subunit beta F-actin capping protein beta subunit capZ beta capping protein (actin filament) muscle Z-line, beta
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36

mRNA and Protein(s)

mRNA	Protein	Name
XM_006239174.3	XP_006239236.1	F-actin-capping protein subunit beta isoform X3
NM_001005903.1	NP_001005903.1	F-actin-capping protein subunit beta
XM_006239175.3	XP_006239237.1	F-actin-capping protein subunit beta isoform X4
XM_006239172.3	XP_006239234.1	F-actin-capping protein subunit beta isoform X2
XM_006239171.3	XP_006239233.1	F-actin-capping protein subunit beta isoform X1
XM_006239177.3	XP_006239239.1	F-actin-capping protein subunit beta isoform X5

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CAPZB	XP_005617941.1
Schizosaccharomyces pombe (fission yeast)	acp2	NP_593619.3
Neurospora crassa	NCU07471	XP_963750.2
Homo sapiens (human)	CAPZB	NP_001269091.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007864	XP_317628.1
Caenorhabditis elegans (roundworm)	cap-2	NP_496336.1
Oryza sativa (rice)	Os03g0381200	NP_001050240.1
Pan troglodytes (chimpanzee)	CAPZB	XP_003307887.1
Rattus norvegicus (Norway rat)	Capzb	NP_001005903.1
Gallus gallus (chicken)	CAPZB	NP_001167000.1
Danio rerio (zebrafish)	capzb	NP_956229.1
Saccharomyces cerevisiae (baker's yeast)	CAP2	NP_012230.3
Kluyveromyces lactis	KLLA0E04225g	XP_454134.1
Eremothecium gossypii	AGOS_ADL101C	NP_983995.1
Bos taurus (cattle)	CAPZB	NP_788821.1
Magnaporthe oryzae (rice blast fungus)	MGG_09902	XP_003709997.1
Mus musculus (house mouse)	Capzb	NP_001258334.1
Drosophila melanogaster (fruit fly)	cpb	NP_477005.1
Arabidopsis thaliana (thale cress)	AT1G71790	NP_177324.2

Gene Ontology
Bibliography

Related articles in PubMed

A recurrent de novo mutation in ACTG1 causes isolated ocular coloboma.
Rainger J, Williamson KA, Soares DC, Truch J, Kurian D, Gillessen-Kaesbach G, Seawright A, Prendergast J, Halachev M, Wheeler A, McTeir L, Gill AC, van Heyningen V, Davey MG, , FitzPatrick DR
Human mutation38(8)942-946(2017 Aug)

Myofibril growth during cardiac hypertrophy is regulated through dual phosphorylation and acetylation of the actin capping protein CapZ.
Lin YH, Warren CM, Li J, McKinsey TA, Russell B
Cellular signalling28(8)1015-24(2016 08)

Cyclic mechanical strain of myocytes modifies CapZ?1 post translationally via PKC?.
Lin YH, Swanson ER, Li J, Mkrtschjan MA, Russell B
Journal of muscle research and cell motility36(4-5)329-37(2015 Oct)

CapZ regulates autophagosomal membrane shaping by promoting actin assembly inside the isolation?membrane.
Mi N, Chen Y, Wang S, Chen M, Zhao M, Yang G, Ma M, Su Q, Luo S, Shi J, Xu J, Guo Q, Gao N, Sun Y, Chen Z, Yu L
Nature cell biology17(9)1112-23(2015 Sep)

Clathrin-independent trafficking of AMPA receptors.
Glebov OO, Tigaret CM, Mellor JR, Henley JM
The Journal of neuroscience : the official journal of the Society for Neuroscience35(12)4830-6(2015 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The goal of this study was to test the hypothesis that actin filament assembly during cardiomyocyte growth is regulated by post-translational modifications (PTMs) of CapZbeta1.
Title: Myofibril growth during cardiac hypertrophy is regulated through dual phosphorylation and acetylation of the actin capping protein CapZ.

with strain there was significant PKCepsilon translocation to the Z-disc and co-localization with CapZbeta1 or alpha-actinin, which was quantified on confocal images.
Title: Cyclic mechanical strain of myocytes modifies CapZ?1 post translationally via PKC?.

Binding of CapZ to PtdIns(3)P, which is enriched in omegasomes, stimulates actin polymerization.
Title: CapZ regulates autophagosomal membrane shaping by promoting actin assembly inside the isolation?membrane.

findings reveal a novel role for neuronal clathrin-independent endocytosis controlled by actin dynamics.
Title: Clathrin-independent trafficking of AMPA receptors.

Although ADF and cofilin-1 have many redundant functions, each of these isoforms has functional differences that affect F-actin structures, cell adhesion and lamellipodial dynamics, all of which are important determinants of cell migration.
Title: Non-overlapping activities of ADF and cofilin-1 during the migration of metastatic breast tumor cells.

The following Capzb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Capzb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa10710	NM_001005903.1 Latest version!	Rattus norvegicus capping actin protein of muscle Z-line subunit beta (Capzb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
ORa28752	XM_006239171.3 Latest version!	Rattus norvegicus capping actin protein of muscle Z-line beta subunit (Capzb), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa28753	XM_006239172.3 Latest version!	Rattus norvegicus capping actin protein of muscle Z-line beta subunit (Capzb), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa28755	XM_006239174.3 Latest version!	Rattus norvegicus capping actin protein of muscle Z-line beta subunit (Capzb), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa28756	XM_006239175.3 Latest version!	Rattus norvegicus capping actin protein of muscle Z-line beta subunit (Capzb), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa28758	XM_006239177.3 Latest version!	Rattus norvegicus capping actin protein of muscle Z-line beta subunit (Capzb), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Capzb ( NM_001005903.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001005903.1 Rattus norvegicus capping actin protein of muscle Z-line subunit beta (Capzb), mRNA.

Price & Availability↑

CloneID	ORa10710
Clone ID Related Accession (Same CDS sequence)	NM_001005903.1
Accession Version	NM_001005903.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 819bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Rattus norvegicus(Norway rat)
Product	F-actin-capping protein subunit beta
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083861.1. On Oct 23, 2004 this sequence version replaced XM_216562.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC083861.1, FQ218507.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAGCGATC AGCAGCTGGA CTGCGCCTTG GACCTGATGA GGCGCCTGCC TCCACAGCAG 
ATTGAGAAAA ACCTCAGCGA TCTGATCGAC CTGGTCCCCA GTCTGTGTGA AGATCTCCTG 
TCTTCTGTTG ACCAGCCCCT GAAAATTGCC AGAGACAAGG TGGTGGGCAA GGACTACCTT 
TTGTGTGACT ACAACAGAGA CGGGGACTCC TATAGGTCAC CATGGAGTAA CAAGTATGAC 
CCTCCTTTGG AAGATGGGGC CATGCCATCT GCTCGGCTCA GAAAGCTGGA GGTAGAGGCC 
AACAATGCCT TCGACCAATA CCGAGACCTG TATTTTGAAG GTGGTGTCTC ATCAGTCTAC 
CTCTGGGATC TCGATCATGG CTTTGCTGGA GTGATCCTCA TAAAGAAGGC TGGGGATGGA 
TCAAAGAAGA TCAAAGGCTG CTGGGATTCC ATCCACGTGG TGGAAGTGCA GGAGAAGTCC 
AGTGGCCGTA CTGCCCATTA CAAGTTGACC TCCACAGTGA TGCTATGGCT GCAAACCAAC 
AAATCCGGCT CAGGCACCAT GAACCTGGGA GGCAGCCTAA CCAGACAGAT GGAGAAGGAC 
GAAACTGTGA GTGACTGTTC CCCACACATA GCCAACATTG GGCGCCTGGT GGAGGACATG 
GAAAACAAAA TCAGAAGCAC GCTGAATGAG ATCTACTTTG GAAAAACAAA GGACATCGTC 
AACGGGCTGA GGTCTGTGCA GACGTTTGCA GACAAATCAA AGCAGGAAGC CCTTAAGAAT 
GACCTGGTGG AAGCCTTGAA GAGAAAGCAG CAGTGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001005903.1
CDS	83..901
Translation	MSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSVQTFADKSKQEALKNDLVEALKRKQQC

Target ORF information:

RefSeq Version	NM_001005903.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus capping actin protein of muscle Z-line subunit beta (Capzb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001005903.1

ORF Insert Sequence:

ATGAGCGATC AGCAGCTGGA CTGCGCCTTG GACCTGATGA GGCGCCTGCC TCCACAGCAG 
ATTGAGAAAA ACCTCAGCGA TCTGATCGAC CTGGTCCCCA GTCTGTGTGA AGATCTCCTG 
TCTTCTGTTG ACCAGCCCCT GAAAATTGCC AGAGACAAGG TGGTGGGCAA GGACTACCTT 
TTGTGTGACT ACAACAGAGA CGGGGACTCC TATAGGTCAC CATGGAGTAA CAAGTATGAC 
CCTCCTTTGG AAGATGGGGC CATGCCATCT GCTCGGCTCA GAAAGCTGGA GGTAGAGGCC 
AACAATGCCT TCGACCAATA CCGAGACCTG TATTTTGAAG GTGGTGTCTC ATCAGTCTAC 
CTCTGGGATC TCGATCATGG CTTTGCTGGA GTGATCCTCA TAAAGAAGGC TGGGGATGGA 
TCAAAGAAGA TCAAAGGCTG CTGGGATTCC ATCCACGTGG TGGAAGTGCA GGAGAAGTCC 
AGTGGCCGTA CTGCCCATTA CAAGTTGACC TCCACAGTGA TGCTATGGCT GCAAACCAAC 
AAATCCGGCT CAGGCACCAT GAACCTGGGA GGCAGCCTAA CCAGACAGAT GGAGAAGGAC 
GAAACTGTGA GTGACTGTTC CCCACACATA GCCAACATTG GGCGCCTGGT GGAGGACATG 
GAAAACAAAA TCAGAAGCAC GCTGAATGAG ATCTACTTTG GAAAAACAAA GGACATCGTC 
AACGGGCTGA GGTCTGTGCA GACGTTTGCA GACAAATCAA AGCAGGAAGC CCTTAAGAAT 
GACCTGGTGG AAGCCTTGAA GAGAAAGCAG CAGTGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Capzb ( XM_006239171.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006239233.1 Rattus norvegicus capping actin protein of muscle Z-line beta subunit (Capzb), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa28752
Clone ID Related Accession (Same CDS sequence)	XM_006239171.3
Accession Version	XM_006239171.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 996bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	F-actin-capping protein subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006239171.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGCATC CTAGCAGGCG CAGCCTTCCT TTCCCCCTGA ACTGTCAGCT TGTAAGGGTT 
GGAACTGCTG ATTATGGAGG TGCCGCTGAT CAGACCATGT GCATCAACCA AGTGGAACAG 
TCTGAGGGCT TCACGTGGCA AGACGGACGG TCTGAAATGA ACTCTAGCGA TCAGCAGCTG 
GACTGCGCCT TGGACCTGAT GAGGCGCCTG CCTCCACAGC AGATTGAGAA AAACCTCAGC 
GATCTGATCG ACCTGGTCCC CAGTCTGTGT GAAGATCTCC TGTCTTCTGT TGACCAGCCC 
CTGAAAATTG CCAGAGACAA GGTGGTGGGC AAGGACTACC TTTTGTGTGA CTACAACAGA 
GACGGGGACT CCTATAGGTC ACCATGGAGT AACAAGTATG ACCCTCCTTT GGAAGATGGG 
GCCATGCCAT CTGCTCGGCT CAGAAAGCTG GAGGTAGAGG CCAACAATGC CTTCGACCAA 
TACCGAGACC TGTATTTTGA AGGTGGTGTC TCATCAGTCT ACCTCTGGGA TCTCGATCAT 
GGCTTTGCTG GAGTGATCCT CATAAAGAAG GCTGGGGATG GATCAAAGAA GATCAAAGGC 
TGCTGGGATT CCATCCACGT GGTGGAAGTG CAGGAGAAGT CCAGTGGCCG TACTGCCCAT 
TACAAGTTGA CCTCCACAGT GATGCTATGG CTGCAAACCA ACAAATCCGG CTCAGGCACC 
ATGAACCTGG GAGGCAGCCT AACCAGACAG ATGGAGAAGG ACGAAACTGT GAGTGACTGT 
TCCCCACACA TAGCCAACAT TGGGCGCCTG GTGGAGGACA TGGAAAACAA AATCAGAAGC 
ACGCTGAATG AGATCTACTT TGGAAAAACA AAGGACATCG TCAACGGGCT GAGATCTCTT 
GACGCTATCC CCGACAACCA CAAGTTTAAG CAGTTGCAGA GGGAACTTTC TCAAGTGCTG 
ACCCAGCGCC AGGTCTACAT CCAGCCTGAT AATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006239233.1
CDS	504..1499
Translation	MMHPSRRSLPFPLNCQLVRVGTADYGGAADQTMCINQVEQSEGFTWQDGRSEMNSSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSLDAIPDNHKFKQLQRELSQVLTQRQVYIQPDN

Target ORF information:

RefSeq Version	XM_006239171.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus capping actin protein of muscle Z-line beta subunit (Capzb), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006239171.3

ORF Insert Sequence:

ATGATGCATC CTAGCAGGCG CAGCCTTCCT TTCCCCCTGA ACTGTCAGCT TGTAAGGGTT 
GGAACTGCTG ATTATGGAGG TGCCGCTGAT CAGACCATGT GCATCAACCA AGTGGAACAG 
TCTGAGGGCT TCACGTGGCA AGACGGACGG TCTGAAATGA ACTCTAGCGA TCAGCAGCTG 
GACTGCGCCT TGGACCTGAT GAGGCGCCTG CCTCCACAGC AGATTGAGAA AAACCTCAGC 
GATCTGATCG ACCTGGTCCC CAGTCTGTGT GAAGATCTCC TGTCTTCTGT TGACCAGCCC 
CTGAAAATTG CCAGAGACAA GGTGGTGGGC AAGGACTACC TTTTGTGTGA CTACAACAGA 
GACGGGGACT CCTATAGGTC ACCATGGAGT AACAAGTATG ACCCTCCTTT GGAAGATGGG 
GCCATGCCAT CTGCTCGGCT CAGAAAGCTG GAGGTAGAGG CCAACAATGC CTTCGACCAA 
TACCGAGACC TGTATTTTGA AGGTGGTGTC TCATCAGTCT ACCTCTGGGA TCTCGATCAT 
GGCTTTGCTG GAGTGATCCT CATAAAGAAG GCTGGGGATG GATCAAAGAA GATCAAAGGC 
TGCTGGGATT CCATCCACGT GGTGGAAGTG CAGGAGAAGT CCAGTGGCCG TACTGCCCAT 
TACAAGTTGA CCTCCACAGT GATGCTATGG CTGCAAACCA ACAAATCCGG CTCAGGCACC 
ATGAACCTGG GAGGCAGCCT AACCAGACAG ATGGAGAAGG ACGAAACTGT GAGTGACTGT 
TCCCCACACA TAGCCAACAT TGGGCGCCTG GTGGAGGACA TGGAAAACAA AATCAGAAGC 
ACGCTGAATG AGATCTACTT TGGAAAAACA AAGGACATCG TCAACGGGCT GAGATCTCTT 
GACGCTATCC CCGACAACCA CAAGTTTAAG CAGTTGCAGA GGGAACTTTC TCAAGTGCTG 
ACCCAGCGCC AGGTCTACAT CCAGCCTGAT AATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Capzb ( XM_006239172.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006239234.1 Rattus norvegicus capping actin protein of muscle Z-line beta subunit (Capzb), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa28753
Clone ID Related Accession (Same CDS sequence)	XM_006239172.3
Accession Version	XM_006239172.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 981bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	F-actin-capping protein subunit beta isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006239172.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGCATC CTAGCAGGCG CAGCCTTCCT TTCCCCCTGA ACTGTCAGCT TGTAAGGGTT 
GGAACTGCTG ATTATGGAGG TGCCGCTGAT CAGACCATGT GCATCAACCA AGTGGAACAG 
TCTGAGGGCT TCACGTGGCA AGACGGACGG TCTGAAATGA ACTCTAGCGA TCAGCAGCTG 
GACTGCGCCT TGGACCTGAT GAGGCGCCTG CCTCCACAGC AGATTGAGAA AAACCTCAGC 
GATCTGATCG ACCTGGTCCC CAGTCTGTGT GAAGATCTCC TGTCTTCTGT TGACCAGCCC 
CTGAAAATTG CCAGAGACAA GGTGGTGGGC AAGGACTACC TTTTGTGTGA CTACAACAGA 
GACGGGGACT CCTATAGGTC ACCATGGAGT AACAAGTATG ACCCTCCTTT GGAAGATGGG 
GCCATGCCAT CTGCTCGGCT CAGAAAGCTG GAGGTAGAGG CCAACAATGC CTTCGACCAA 
TACCGAGACC TGTATTTTGA AGGTGGTGTC TCATCAGTCT ACCTCTGGGA TCTCGATCAT 
GGCTTTGCTG GAGTGATCCT CATAAAGAAG GCTGGGGATG GATCAAAGAA GATCAAAGGC 
TGCTGGGATT CCATCCACGT GGTGGAAGTG CAGGAGAAGT CCAGTGGCCG TACTGCCCAT 
TACAAGTTGA CCTCCACAGT GATGCTATGG CTGCAAACCA ACAAATCCGG CTCAGGCACC 
ATGAACCTGG GAGGCAGCCT AACCAGACAG ATGGAGAAGG ACGAAACTGT GAGTGACTGT 
TCCCCACACA TAGCCAACAT TGGGCGCCTG GTGGAGGACA TGGAAAACAA AATCAGAAGC 
ACGCTGAATG AGATCTACTT TGGAAAAACA AAGGACATCG TCAACGGGCT GAGGTCTGTG 
CAGACGTTTG CAGACAAATC AAAGCAGGAA GCCCTTAAGA ATGACCTGGT GGAAGCCTTG 
AAGAGAAAGC AGCAGTGTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006239234.1
CDS	497..1477
Translation	MMHPSRRSLPFPLNCQLVRVGTADYGGAADQTMCINQVEQSEGFTWQDGRSEMNSSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSVQTFADKSKQEALKNDLVEALKRKQQC

Target ORF information:

RefSeq Version	XM_006239172.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus capping actin protein of muscle Z-line beta subunit (Capzb), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006239172.3

ORF Insert Sequence:

ATGATGCATC CTAGCAGGCG CAGCCTTCCT TTCCCCCTGA ACTGTCAGCT TGTAAGGGTT 
GGAACTGCTG ATTATGGAGG TGCCGCTGAT CAGACCATGT GCATCAACCA AGTGGAACAG 
TCTGAGGGCT TCACGTGGCA AGACGGACGG TCTGAAATGA ACTCTAGCGA TCAGCAGCTG 
GACTGCGCCT TGGACCTGAT GAGGCGCCTG CCTCCACAGC AGATTGAGAA AAACCTCAGC 
GATCTGATCG ACCTGGTCCC CAGTCTGTGT GAAGATCTCC TGTCTTCTGT TGACCAGCCC 
CTGAAAATTG CCAGAGACAA GGTGGTGGGC AAGGACTACC TTTTGTGTGA CTACAACAGA 
GACGGGGACT CCTATAGGTC ACCATGGAGT AACAAGTATG ACCCTCCTTT GGAAGATGGG 
GCCATGCCAT CTGCTCGGCT CAGAAAGCTG GAGGTAGAGG CCAACAATGC CTTCGACCAA 
TACCGAGACC TGTATTTTGA AGGTGGTGTC TCATCAGTCT ACCTCTGGGA TCTCGATCAT 
GGCTTTGCTG GAGTGATCCT CATAAAGAAG GCTGGGGATG GATCAAAGAA GATCAAAGGC 
TGCTGGGATT CCATCCACGT GGTGGAAGTG CAGGAGAAGT CCAGTGGCCG TACTGCCCAT 
TACAAGTTGA CCTCCACAGT GATGCTATGG CTGCAAACCA ACAAATCCGG CTCAGGCACC 
ATGAACCTGG GAGGCAGCCT AACCAGACAG ATGGAGAAGG ACGAAACTGT GAGTGACTGT 
TCCCCACACA TAGCCAACAT TGGGCGCCTG GTGGAGGACA TGGAAAACAA AATCAGAAGC 
ACGCTGAATG AGATCTACTT TGGAAAAACA AAGGACATCG TCAACGGGCT GAGGTCTGTG 
CAGACGTTTG CAGACAAATC AAAGCAGGAA GCCCTTAAGA ATGACCTGGT GGAAGCCTTG 
AAGAGAAAGC AGCAGTGTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Capzb ( XM_006239174.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006239236.1 Rattus norvegicus capping actin protein of muscle Z-line beta subunit (Capzb), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa28755
Clone ID Related Accession (Same CDS sequence)	XM_006239174.3
Accession Version	XM_006239174.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 924bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	F-actin-capping protein subunit beta isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006239174.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGCATC CTAGCAGGCG CAGCCTTCCT TTCCCCCTGA ACTGTCAGCT TGTAAGGGTT 
GGAACTGCTG ATTATGGAGG TGCCGCTGAT CAGAGCGATC AGCAGCTGGA CTGCGCCTTG 
GACCTGATGA GGCGCCTGCC TCCACAGCAG ATTGAGAAAA ACCTCAGCGA TCTGATCGAC 
CTGGTCCCCA GTCTGTGTGA AGATCTCCTG TCTTCTGTTG ACCAGCCCCT GAAAATTGCC 
AGAGACAAGG TGGTGGGCAA GGACTACCTT TTGTGTGACT ACAACAGAGA CGGGGACTCC 
TATAGGTCAC CATGGAGTAA CAAGTATGAC CCTCCTTTGG AAGATGGGGC CATGCCATCT 
GCTCGGCTCA GAAAGCTGGA GGTAGAGGCC AACAATGCCT TCGACCAATA CCGAGACCTG 
TATTTTGAAG GTGGTGTCTC ATCAGTCTAC CTCTGGGATC TCGATCATGG CTTTGCTGGA 
GTGATCCTCA TAAAGAAGGC TGGGGATGGA TCAAAGAAGA TCAAAGGCTG CTGGGATTCC 
ATCCACGTGG TGGAAGTGCA GGAGAAGTCC AGTGGCCGTA CTGCCCATTA CAAGTTGACC 
TCCACAGTGA TGCTATGGCT GCAAACCAAC AAATCCGGCT CAGGCACCAT GAACCTGGGA 
GGCAGCCTAA CCAGACAGAT GGAGAAGGAC GAAACTGTGA GTGACTGTTC CCCACACATA 
GCCAACATTG GGCGCCTGGT GGAGGACATG GAAAACAAAA TCAGAAGCAC GCTGAATGAG 
ATCTACTTTG GAAAAACAAA GGACATCGTC AACGGGCTGA GATCTCTTGA CGCTATCCCC 
GACAACCACA AGTTTAAGCA GTTGCAGAGG GAACTTTCTC AAGTGCTGAC CCAGCGCCAG 
GTCTACATCC AGCCTGATAA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006239236.1
CDS	501..1424
Translation	MMHPSRRSLPFPLNCQLVRVGTADYGGAADQSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSLDAIPDNHKFKQLQRELSQVLTQRQVYIQPDN

Target ORF information:

RefSeq Version	XM_006239174.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus capping actin protein of muscle Z-line beta subunit (Capzb), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006239174.3

ORF Insert Sequence:

ATGATGCATC CTAGCAGGCG CAGCCTTCCT TTCCCCCTGA ACTGTCAGCT TGTAAGGGTT 
GGAACTGCTG ATTATGGAGG TGCCGCTGAT CAGAGCGATC AGCAGCTGGA CTGCGCCTTG 
GACCTGATGA GGCGCCTGCC TCCACAGCAG ATTGAGAAAA ACCTCAGCGA TCTGATCGAC 
CTGGTCCCCA GTCTGTGTGA AGATCTCCTG TCTTCTGTTG ACCAGCCCCT GAAAATTGCC 
AGAGACAAGG TGGTGGGCAA GGACTACCTT TTGTGTGACT ACAACAGAGA CGGGGACTCC 
TATAGGTCAC CATGGAGTAA CAAGTATGAC CCTCCTTTGG AAGATGGGGC CATGCCATCT 
GCTCGGCTCA GAAAGCTGGA GGTAGAGGCC AACAATGCCT TCGACCAATA CCGAGACCTG 
TATTTTGAAG GTGGTGTCTC ATCAGTCTAC CTCTGGGATC TCGATCATGG CTTTGCTGGA 
GTGATCCTCA TAAAGAAGGC TGGGGATGGA TCAAAGAAGA TCAAAGGCTG CTGGGATTCC 
ATCCACGTGG TGGAAGTGCA GGAGAAGTCC AGTGGCCGTA CTGCCCATTA CAAGTTGACC 
TCCACAGTGA TGCTATGGCT GCAAACCAAC AAATCCGGCT CAGGCACCAT GAACCTGGGA 
GGCAGCCTAA CCAGACAGAT GGAGAAGGAC GAAACTGTGA GTGACTGTTC CCCACACATA 
GCCAACATTG GGCGCCTGGT GGAGGACATG GAAAACAAAA TCAGAAGCAC GCTGAATGAG 
ATCTACTTTG GAAAAACAAA GGACATCGTC AACGGGCTGA GATCTCTTGA CGCTATCCCC 
GACAACCACA AGTTTAAGCA GTTGCAGAGG GAACTTTCTC AAGTGCTGAC CCAGCGCCAG 
GTCTACATCC AGCCTGATAA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Capzb ( XM_006239175.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006239237.1 Rattus norvegicus capping actin protein of muscle Z-line beta subunit (Capzb), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa28756
Clone ID Related Accession (Same CDS sequence)	XM_006239175.3
Accession Version	XM_006239175.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 909bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	F-actin-capping protein subunit beta isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006239175.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGCATC CTAGCAGGCG CAGCCTTCCT TTCCCCCTGA ACTGTCAGCT TGTAAGGGTT 
GGAACTGCTG ATTATGGAGG TGCCGCTGAT CAGAGCGATC AGCAGCTGGA CTGCGCCTTG 
GACCTGATGA GGCGCCTGCC TCCACAGCAG ATTGAGAAAA ACCTCAGCGA TCTGATCGAC 
CTGGTCCCCA GTCTGTGTGA AGATCTCCTG TCTTCTGTTG ACCAGCCCCT GAAAATTGCC 
AGAGACAAGG TGGTGGGCAA GGACTACCTT TTGTGTGACT ACAACAGAGA CGGGGACTCC 
TATAGGTCAC CATGGAGTAA CAAGTATGAC CCTCCTTTGG AAGATGGGGC CATGCCATCT 
GCTCGGCTCA GAAAGCTGGA GGTAGAGGCC AACAATGCCT TCGACCAATA CCGAGACCTG 
TATTTTGAAG GTGGTGTCTC ATCAGTCTAC CTCTGGGATC TCGATCATGG CTTTGCTGGA 
GTGATCCTCA TAAAGAAGGC TGGGGATGGA TCAAAGAAGA TCAAAGGCTG CTGGGATTCC 
ATCCACGTGG TGGAAGTGCA GGAGAAGTCC AGTGGCCGTA CTGCCCATTA CAAGTTGACC 
TCCACAGTGA TGCTATGGCT GCAAACCAAC AAATCCGGCT CAGGCACCAT GAACCTGGGA 
GGCAGCCTAA CCAGACAGAT GGAGAAGGAC GAAACTGTGA GTGACTGTTC CCCACACATA 
GCCAACATTG GGCGCCTGGT GGAGGACATG GAAAACAAAA TCAGAAGCAC GCTGAATGAG 
ATCTACTTTG GAAAAACAAA GGACATCGTC AACGGGCTGA GGTCTGTGCA GACGTTTGCA 
GACAAATCAA AGCAGGAAGC CCTTAAGAAT GACCTGGTGG AAGCCTTGAA GAGAAAGCAG 
CAGTGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006239237.1
CDS	492..1400
Translation	MMHPSRRSLPFPLNCQLVRVGTADYGGAADQSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSVQTFADKSKQEALKNDLVEALKRKQQC

Target ORF information:

RefSeq Version	XM_006239175.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus capping actin protein of muscle Z-line beta subunit (Capzb), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006239175.3

ORF Insert Sequence:

ATGATGCATC CTAGCAGGCG CAGCCTTCCT TTCCCCCTGA ACTGTCAGCT TGTAAGGGTT 
GGAACTGCTG ATTATGGAGG TGCCGCTGAT CAGAGCGATC AGCAGCTGGA CTGCGCCTTG 
GACCTGATGA GGCGCCTGCC TCCACAGCAG ATTGAGAAAA ACCTCAGCGA TCTGATCGAC 
CTGGTCCCCA GTCTGTGTGA AGATCTCCTG TCTTCTGTTG ACCAGCCCCT GAAAATTGCC 
AGAGACAAGG TGGTGGGCAA GGACTACCTT TTGTGTGACT ACAACAGAGA CGGGGACTCC 
TATAGGTCAC CATGGAGTAA CAAGTATGAC CCTCCTTTGG AAGATGGGGC CATGCCATCT 
GCTCGGCTCA GAAAGCTGGA GGTAGAGGCC AACAATGCCT TCGACCAATA CCGAGACCTG 
TATTTTGAAG GTGGTGTCTC ATCAGTCTAC CTCTGGGATC TCGATCATGG CTTTGCTGGA 
GTGATCCTCA TAAAGAAGGC TGGGGATGGA TCAAAGAAGA TCAAAGGCTG CTGGGATTCC 
ATCCACGTGG TGGAAGTGCA GGAGAAGTCC AGTGGCCGTA CTGCCCATTA CAAGTTGACC 
TCCACAGTGA TGCTATGGCT GCAAACCAAC AAATCCGGCT CAGGCACCAT GAACCTGGGA 
GGCAGCCTAA CCAGACAGAT GGAGAAGGAC GAAACTGTGA GTGACTGTTC CCCACACATA 
GCCAACATTG GGCGCCTGGT GGAGGACATG GAAAACAAAA TCAGAAGCAC GCTGAATGAG 
ATCTACTTTG GAAAAACAAA GGACATCGTC AACGGGCTGA GGTCTGTGCA GACGTTTGCA 
GACAAATCAA AGCAGGAAGC CCTTAAGAAT GACCTGGTGG AAGCCTTGAA GAGAAAGCAG 
CAGTGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Capzb ( XM_006239177.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006239239.1 Rattus norvegicus capping actin protein of muscle Z-line beta subunit (Capzb), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa28758
Clone ID Related Accession (Same CDS sequence)	XM_006239177.3
Accession Version	XM_006239177.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	F-actin-capping protein subunit beta isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006239177.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCGATC AGCAGCTGGA CTGCGCCTTG GACCTGATGA GGCGCCTGCC TCCACAGCAG 
ATTGAGAAAA ACCTCAGCGA TCTGATCGAC CTGGTCCCCA GTCTGTGTGA AGATCTCCTG 
TCTTCTGTTG ACCAGCCCCT GAAAATTGCC AGAGACAAGG TGGTGGGCAA GGACTACCTT 
TTGTGTGACT ACAACAGAGA CGGGGACTCC TATAGGTCAC CATGGAGTAA CAAGTATGAC 
CCTCCTTTGG AAGATGGGGC CATGCCATCT GCTCGGCTCA GAAAGCTGGA GGTAGAGGCC 
AACAATGCCT TCGACCAATA CCGAGACCTG TATTTTGAAG GTGGTGTCTC ATCAGTCTAC 
CTCTGGGATC TCGATCATGG CTTTGCTGGA GTGATCCTCA TAAAGAAGGC TGGGGATGGA 
TCAAAGAAGA TCAAAGGCTG CTGGGATTCC ATCCACGTGG TGGAAGTGCA GGAGAAGTCC 
AGTGGCCGTA CTGCCCATTA CAAGTTGACC TCCACAGTGA TGCTATGGCT GCAAACCAAC 
AAATCCGGCT CAGGCACCAT GAACCTGGGA GGCAGCCTAA CCAGACAGAT GGAGAAGGAC 
GAAACTGTGA GTGACTGTTC CCCACACATA GCCAACATTG GGCGCCTGGT GGAGGACATG 
GAAAACAAAA TCAGAAGCAC GCTGAATGAG ATCTACTTTG GAAAAACAAA GGACATCGTC 
AACGGGCTGA GATCTCTTGA CGCTATCCCC GACAACCACA AGTTTAAGCA GTTGCAGAGG 
GAACTTTCTC AAGTGCTGAC CCAGCGCCAG GTCTACATCC AGCCTGATAA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006239239.1
CDS	118..951
Translation	MSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSLDAIPDNHKFKQLQRELSQVLTQRQVYIQPDN

Target ORF information:

RefSeq Version	XM_006239177.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus capping actin protein of muscle Z-line beta subunit (Capzb), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006239177.3

ORF Insert Sequence:

ATGAGCGATC AGCAGCTGGA CTGCGCCTTG GACCTGATGA GGCGCCTGCC TCCACAGCAG 
ATTGAGAAAA ACCTCAGCGA TCTGATCGAC CTGGTCCCCA GTCTGTGTGA AGATCTCCTG 
TCTTCTGTTG ACCAGCCCCT GAAAATTGCC AGAGACAAGG TGGTGGGCAA GGACTACCTT 
TTGTGTGACT ACAACAGAGA CGGGGACTCC TATAGGTCAC CATGGAGTAA CAAGTATGAC 
CCTCCTTTGG AAGATGGGGC CATGCCATCT GCTCGGCTCA GAAAGCTGGA GGTAGAGGCC 
AACAATGCCT TCGACCAATA CCGAGACCTG TATTTTGAAG GTGGTGTCTC ATCAGTCTAC 
CTCTGGGATC TCGATCATGG CTTTGCTGGA GTGATCCTCA TAAAGAAGGC TGGGGATGGA 
TCAAAGAAGA TCAAAGGCTG CTGGGATTCC ATCCACGTGG TGGAAGTGCA GGAGAAGTCC 
AGTGGCCGTA CTGCCCATTA CAAGTTGACC TCCACAGTGA TGCTATGGCT GCAAACCAAC 
AAATCCGGCT CAGGCACCAT GAACCTGGGA GGCAGCCTAA CCAGACAGAT GGAGAAGGAC 
GAAACTGTGA GTGACTGTTC CCCACACATA GCCAACATTG GGCGCCTGGT GGAGGACATG 
GAAAACAAAA TCAGAAGCAC GCTGAATGAG ATCTACTTTG GAAAAACAAA GGACATCGTC 
AACGGGCTGA GATCTCTTGA CGCTATCCCC GACAACCACA AGTTTAAGCA GTTGCAGAGG 
GAACTTTCTC AAGTGCTGAC CCAGCGCCAG GTCTACATCC AGCCTGATAA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A recurrent de novo mutation in ACTG1 causes isolated ocular coloboma.
Human mutation38(8)942-946(2017 Aug)
Rainger J,Williamson KA,Soares DC,Truch J,Kurian D,Gillessen-Kaesbach G,Seawright A,Prendergast J,Halachev M,Wheeler A,McTeir L,Gill AC,van Heyningen V,Davey MG,,FitzPatrick DR

Myofibril growth during cardiac hypertrophy is regulated through dual phosphorylation and acetylation of the actin capping protein CapZ.
Cellular signalling28(8)1015-24(2016 08)
Lin YH,Warren CM,Li J,McKinsey TA,Russell B

Cyclic mechanical strain of myocytes modifies CapZ?1 post translationally via PKC?.
Journal of muscle research and cell motility36(4-5)329-37(2015 Oct)
Lin YH,Swanson ER,Li J,Mkrtschjan MA,Russell B

CapZ regulates autophagosomal membrane shaping by promoting actin assembly inside the isolation?membrane.
Nature cell biology17(9)1112-23(2015 Sep)
Mi N,Chen Y,Wang S,Chen M,Zhao M,Yang G,Ma M,Su Q,Luo S,Shi J,Xu J,Guo Q,Gao N,Sun Y,Chen Z,Yu L

Clathrin-independent trafficking of AMPA receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience35(12)4830-6(2015 Mar)
Glebov OO,Tigaret CM,Mellor JR,Henley JM

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Capzb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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