Dnali1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dnali1
Entrez Gene ID	298524
Full Name	dynein, axonemal, light intermediate chain 1
General protein information	Preferred Names dynein, axonemal, light intermediate chain 1 Names axonemal dynein light intermediate polypeptide 1 dynein, axonemal, light intermediate polypeptide 1 inner dynein arm light chain, axonemal
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36

mRNA and Protein(s)

mRNA	Protein	Name
NM_001031647.1	NP_001026817.1	axonemal dynein light intermediate polypeptide 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	DNALI1	NP_003453.2
Rattus norvegicus (Norway rat)	Dnali1	NP_001026817.1
Drosophila melanogaster (fruit fly)	CG6971	NP_650128.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004030	XP_318486.5
Xenopus tropicalis (tropical clawed frog)	dnali1	NP_001016687.1
	DNALI1	XP_001111996.1
Canis lupus familiaris (dog)	DNALI1	XP_539590.3
Bos taurus (cattle)	DNALI1	NP_001178228.2
Danio rerio (zebrafish)	dnali1	NP_001103584.2
Pan troglodytes (chimpanzee)	DNALI1	XP_001169634.1
Mus musculus (house mouse)	Dnali1	NP_780432.1
Danio rerio (zebrafish)	LOC100536814	XP_003200255.1
Gallus gallus (chicken)	DNALI1	XP_417762.3

Gene Ontology
Bibliography

Related articles in PubMed

A mutation in
Abdelhamed Z, Vuong SM, Hill L, Shula C, Timms A, Beier D, Campbell K, Mangano FT, Stottmann RW, Goto J
Development (Cambridge, England)145(1)(2018 Jan)

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.
Dougherty GW, Loges NT, Klinkenbusch JA, Olbrich H, Pennekamp P, Menchen T, Raidt J, Wallmeier J, Werner C, Westermann C, Ruckert C, Mirra V, Hjeij R, Memari Y, Durbin R, Kolb-Kokocinski A, Praveen K, Kashef MA, Kashef S, Eghtedari F, H?ffner K, Valmari P, Baktai G, Aviram M, Bentur L, Amirav I, Davis EE, Katsanis N, Brueckner M, Shaposhnykov A, Pigino G, Dworniczak B, Omran H
American journal of respiratory cell and molecular biology55(2)213-24(2016 Aug)

Mutations in GAS8, a Gene Encoding a Nexin-Dynein Regulatory Complex Subunit, Cause Primary Ciliary Dyskinesia with Axonemal Disorganization.
Jeanson L, Thomas L, Copin B, Coste A, Sermet-Gaudelus I, Dastot-Le Moal F, Duquesnoy P, Montantin G, Collot N, Tissier S, Papon JF, Clement A, Louis B, Escudier E, Amselem S, Legendre M
Human mutation37(8)776-85(2016 08)

ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry.
Hjeij R, Lindstrand A, Francis R, Zariwala MA, Liu X, Li Y, Damerla R, Dougherty GW, Abouhamed M, Olbrich H, Loges NT, Pennekamp P, Davis EE, Carvalho CM, Pehlivan D, Werner C, Raidt J, K?hler G, H?ffner K, Reyes-Mugica M, Lupski JR, Leigh MW, Rosenfeld M, Morgan LC, Knowles MR, Lo CW, Katsanis N, Omran H
American journal of human genetics93(2)357-67(2013 Aug)

Deletions and point mutations of LRRC50 cause primary ciliary dyskinesia due to dynein arm defects.
Loges NT, Olbrich H, Becker-Heck A, H?ffner K, Heer A, Reinhard C, Schmidts M, Kispert A, Zariwala MA, Leigh MW, Knowles MR, Zentgraf H, Seithe H, N?rnberg G, N?rnberg P, Reinhardt R, Omran H
American journal of human genetics85(6)883-9(2009 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Dnali1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dnali1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08043	NM_001031647.1 Latest version!	Rattus norvegicus dynein, axonemal, light intermediate chain 1 (Dnali1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dnali1 ( NM_001031647.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001026817.1 Rattus norvegicus dynein, axonemal, light intermediate chain 1 (Dnali1), mRNA.

Price & Availability↑

CloneID	ORa08043
Clone ID Related Accession (Same CDS sequence)	NM_001031647.1
Accession Version	NM_001031647.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	axonemal dynein light intermediate polypeptide 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC099087.1. On Aug 12, 2005 this sequence version replaced XM_233519.2. Sequence Note: This sequence has been modified as follows: removed 23 bp suspected to be vector contamination from the 5' end. ##Evidence-Data-START## Transcript exon combination :: BC099087.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689595, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##

ATGATACCCC CCGCAGACTC TCTGCTCAAA TATGACACCC CGGTGTTGGT GAGCCGGAAT 
ACAGAAAAAC GGAGCCCCAA GGCTCGGCCA CTGAAAGTCA CAGTTCAGCA GCCTGGACCC 
TCTGGTGCAG GCCCACAACC ACCCAAGGCC AAGCTGCCCT CAACTTCCTG TGTCCCAGAT 
CCTACCAAAC AAGCAGAAGA AATCTTGAAT GCCATCCTGC CTCCAAGGGA GTGGGTAGAA 
GACACACAGC TATGGATCCA GCAGGTGTCC AGCACACCCA GCACCAGAAT GGATGTGGTG 
CATCTCCAGG AGCAGCTGGA CCTGAAGCTG CAGCAGAGGC AGGCCAGGGA GACGGGCATC 
TGCCCTGTGC GCAGGGAACT CTACTCCCAG TGTTTTGATG AGCTGATCCG GGAGGTCACC 
ATCAACTGTG CAGAGAGAGG ACTGCTGTTG CTGCGTGTCC GGGATGAGAT CCGCATGACC 
ATCGCTGCCT ACCAGACTCT GTATGAAAGC AGTGTAGCAT TCGGCATGAG GAAGGCACTG 
CAGGCCGAAC AGGGGAAGTC AGACATGGAG AGGAAAATTA CAGAACTGGA GACAGAAAAG 
AGAGACTTGG AGAGGCAAGT GAATGAACAG AAGGCGAAAT GTGAGGCCAC CGAGAAGCGG 
GAGAGCGAGA GGCGACAGGT GGAGGAGAAG AAGCACAATG AGGAGATCCA GTTCCTGAAA 
CGGACTAATC AGCAACTGAA GGCCCAACTG GAAGGCATTA TCGCACCGAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001026817.1
CDS	3..779
Translation	MIPPADSLLKYDTPVLVSRNTEKRSPKARPLKVTVQQPGPSGAGPQPPKAKLPSTSCVPDPTKQAEEILNAILPPREWVEDTQLWIQQVSSTPSTRMDVVHLQEQLDLKLQQRQARETGICPVRRELYSQCFDELIREVTINCAERGLLLLRVRDEIRMTIAAYQTLYESSVAFGMRKALQAEQGKSDMERKITELETEKRDLERQVNEQKAKCEATEKRESERRQVEEKKHNEEIQFLKRTNQQLKAQLEGIIAPKK

Target ORF information:

RefSeq Version	NM_001031647.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dynein, axonemal, light intermediate chain 1 (Dnali1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001031647.1

ORF Insert Sequence:

ATGATACCCC CCGCAGACTC TCTGCTCAAA TATGACACCC CGGTGTTGGT GAGCCGGAAT 
ACAGAAAAAC GGAGCCCCAA GGCTCGGCCA CTGAAAGTCA CAGTTCAGCA GCCTGGACCC 
TCTGGTGCAG GCCCACAACC ACCCAAGGCC AAGCTGCCCT CAACTTCCTG TGTCCCAGAT 
CCTACCAAAC AAGCAGAAGA AATCTTGAAT GCCATCCTGC CTCCAAGGGA GTGGGTAGAA 
GACACACAGC TATGGATCCA GCAGGTGTCC AGCACACCCA GCACCAGAAT GGATGTGGTG 
CATCTCCAGG AGCAGCTGGA CCTGAAGCTG CAGCAGAGGC AGGCCAGGGA GACGGGCATC 
TGCCCTGTGC GCAGGGAACT CTACTCCCAG TGTTTTGATG AGCTGATCCG GGAGGTCACC 
ATCAACTGTG CAGAGAGAGG ACTGCTGTTG CTGCGTGTCC GGGATGAGAT CCGCATGACC 
ATCGCTGCCT ACCAGACTCT GTATGAAAGC AGTGTAGCAT TCGGCATGAG GAAGGCACTG 
CAGGCCGAAC AGGGGAAGTC AGACATGGAG AGGAAAATTA CAGAACTGGA GACAGAAAAG 
AGAGACTTGG AGAGGCAAGT GAATGAACAG AAGGCGAAAT GTGAGGCCAC CGAGAAGCGG 
GAGAGCGAGA GGCGACAGGT GGAGGAGAAG AAGCACAATG AGGAGATCCA GTTCCTGAAA 
CGGACTAATC AGCAACTGAA GGCCCAACTG GAAGGCATTA TCGCACCGAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A mutation in
Development (Cambridge, England)145(1)(2018 Jan)
Abdelhamed Z,Vuong SM,Hill L,Shula C,Timms A,Beier D,Campbell K,Mangano FT,Stottmann RW,Goto J

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.
American journal of respiratory cell and molecular biology55(2)213-24(2016 Aug)
Dougherty GW,Loges NT,Klinkenbusch JA,Olbrich H,Pennekamp P,Menchen T,Raidt J,Wallmeier J,Werner C,Westermann C,Ruckert C,Mirra V,Hjeij R,Memari Y,Durbin R,Kolb-Kokocinski A,Praveen K,Kashef MA,Kashef S,Eghtedari F,H?ffner K,Valmari P,Baktai G,Aviram M,Bentur L,Amirav I,Davis EE,Katsanis N,Brueckner M,Shaposhnykov A,Pigino G,Dworniczak B,Omran H

Mutations in GAS8, a Gene Encoding a Nexin-Dynein Regulatory Complex Subunit, Cause Primary Ciliary Dyskinesia with Axonemal Disorganization.
Human mutation37(8)776-85(2016 08)
Jeanson L,Thomas L,Copin B,Coste A,Sermet-Gaudelus I,Dastot-Le Moal F,Duquesnoy P,Montantin G,Collot N,Tissier S,Papon JF,Clement A,Louis B,Escudier E,Amselem S,Legendre M

ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry.
American journal of human genetics93(2)357-67(2013 Aug)
Hjeij R,Lindstrand A,Francis R,Zariwala MA,Liu X,Li Y,Damerla R,Dougherty GW,Abouhamed M,Olbrich H,Loges NT,Pennekamp P,Davis EE,Carvalho CM,Pehlivan D,Werner C,Raidt J,K?hler G,H?ffner K,Reyes-Mugica M,Lupski JR,Leigh MW,Rosenfeld M,Morgan LC,Knowles MR,Lo CW,Katsanis N,Omran H

Deletions and point mutations of LRRC50 cause primary ciliary dyskinesia due to dynein arm defects.
American journal of human genetics85(6)883-9(2009 Dec)
Loges NT,Olbrich H,Becker-Heck A,H?ffner K,Heer A,Reinhard C,Schmidts M,Kispert A,Zariwala MA,Leigh MW,Knowles MR,Zentgraf H,Seithe H,N?rnberg G,N?rnberg P,Reinhardt R,Omran H

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Dnali1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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