Pole3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pole3
Entrez Gene ID	298098
Full Name	polymerase (DNA directed), epsilon 3, accessory subunit
General protein information	Preferred Names polymerase (DNA directed), epsilon 3, accessory subunit Names DNA polymerase epsilon subunit 3 DNA polymerase II subunit 3 DNA polymerase epsilon subunit p17 DNA-directed DNA polymerase epsilon 3 polymerase (DNA directed), epsilon 3 (p17 subunit)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q24

mRNA and Protein(s)

mRNA	Protein	Name
NM_001007652.2	NP_001007653.1	DNA polymerase epsilon subunit 3

Pathways from BioSystems

Homologies

Homo sapiens (human)	POLE3	NP_059139.3
	POLE3	XP_001101300.1
Canis lupus familiaris (dog)	POLE3	XP_855374.2
Gallus gallus (chicken)	POLE3	NP_001020525.2
Danio rerio (zebrafish)	pole3	NP_957095.1
Drosophila melanogaster (fruit fly)	Chrac-14	NP_476646.2
Bos taurus (cattle)	POLE3	NP_001029562.1
Rattus norvegicus (Norway rat)	Pole3	NP_001007653.1
Rattus norvegicus (Norway rat)	LOC100362333	XP_002729875.1
Pan troglodytes (chimpanzee)	POLE3	NP_001233445.1
Mus musculus (house mouse)	Pole3	NP_067473.2
Xenopus tropicalis (tropical clawed frog)	pole3	NP_001017264.1

Gene Ontology
Bibliography

Related articles in PubMed

ATAC-king the complexity of SAGA during evolution.
Spedale G, Timmers HT, Pijnappel WW
Genes & development26(6)527-41(2012 Mar)

ATP-dependent chromatin remodeling: genetics, genomics and mechanisms.
Hargreaves DC, Crabtree GR
Cell research21(3)396-420(2011 Mar)

Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.
Wang YL, Faiola F, Xu M, Pan S, Martinez E
The Journal of biological chemistry283(49)33808-15(2008 Dec)

DNA polymerase epsilon - more than a polymerase.
Pospiech H, Syv?oja JE
TheScientificWorldJournal387-104(2003 Mar)

Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon.
Li Y, Pursell ZF, Linn S
The Journal of biological chemistry275(30)23247-52(2000 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Pole3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pole3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11381	NM_001007652.2 Latest version!	Rattus norvegicus DNA polymerase epsilon 3, accessory subunit (Pole3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pole3 ( NM_001007652.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001007653.1 Rattus norvegicus DNA polymerase epsilon 3, accessory subunit (Pole3), mRNA.

Price & Availability↑

CloneID	ORa11381
Clone ID Related Accession (Same CDS sequence)	NM_001007652.2
Accession Version	NM_001007652.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 438bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Rattus norvegicus(Norway rat)
Product	DNA polymerase epsilon subunit 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083800.1. On or before Nov 29, 2004 this sequence version replaced XM_216420.2, NM_001007652.1. ##Evidence-Data-START## Transcript exon combination :: BC083800.1, EV768825.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN01906348, SAMN01906349 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGAGA GGCCTGAGGA CCTAAATCTG CCCAACGCCG TCATTACCAG GATCATCAAG 
GAGGCGCTAC CGGACGGTGT CAACATCTCC AAGGAGGCCC GAAGCGCCAT CTCCCGCGCG 
GCCAGTGTTT TCGTTTTGTA TGCCACATCC TGTGCCAATA ACTTTGCAAT GAAAGGAAAG 
CGCAAGACTC TCAATGCCAG TGATGTACTG TCAGCCATGG AAGAGATGGA GTTCCAACGG 
TTCGTAACGC CATTGAAAGA AGCGCTAGAA GCATACAGGC GGGAGCAGAA AGGCAAGAAG 
GAAGCCTCAG AGCAAAAGAA GAAGGACAAA GACAAAAAAG ATTGCGAAGA GCAGGACAAA 
AGCAGAGAGG AGGAGGATGA AGATGAAGAA AGACTGGATG AGGAAGAACA GAACGAAGAG 
GAGGAGGTAG ACAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007653.1
CDS	14..451
Translation	MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKDCEEQDKSREEEDEDEERLDEEEQNEEEEVDN

Target ORF information:

RefSeq Version	NM_001007652.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus DNA polymerase epsilon 3, accessory subunit (Pole3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007652.2

ORF Insert Sequence:

ATGGCGGAGA GGCCTGAGGA CCTAAATCTG CCCAACGCCG TCATTACCAG GATCATCAAG 
GAGGCGCTAC CGGACGGTGT CAACATCTCC AAGGAGGCCC GAAGCGCCAT CTCCCGCGCG 
GCCAGTGTTT TCGTTTTGTA TGCCACATCC TGTGCCAATA ACTTTGCAAT GAAAGGAAAG 
CGCAAGACTC TCAATGCCAG TGATGTACTG TCAGCCATGG AAGAGATGGA GTTCCAACGG 
TTCGTAACGC CATTGAAAGA AGCGCTAGAA GCATACAGGC GGGAGCAGAA AGGCAAGAAG 
GAAGCCTCAG AGCAAAAGAA GAAGGACAAA GACAAAAAAG ATTGCGAAGA GCAGGACAAA 
AGCAGAGAGG AGGAGGATGA AGATGAAGAA AGACTGGATG AGGAAGAACA GAACGAAGAG 
GAGGAGGTAG ACAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ATAC-king the complexity of SAGA during evolution.
Genes & development26(6)527-41(2012 Mar)
Spedale G,Timmers HT,Pijnappel WW

ATP-dependent chromatin remodeling: genetics, genomics and mechanisms.
Cell research21(3)396-420(2011 Mar)
Hargreaves DC,Crabtree GR

Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.
The Journal of biological chemistry283(49)33808-15(2008 Dec)
Wang YL,Faiola F,Xu M,Pan S,Martinez E

DNA polymerase epsilon - more than a polymerase.
TheScientificWorldJournal387-104(2003 Mar)
Pospiech H,Syv?oja JE

Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon.
The Journal of biological chemistry275(30)23247-52(2000 Jul)
Li Y,Pursell ZF,Linn S