Wwp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Wwp1
Entrez Gene ID	297930
Full Name	WW domain containing E3 ubiquitin protein ligase 1
General protein information	Preferred Names WW domain containing E3 ubiquitin protein ligase 1 Names NEDD4-like E3 ubiquitin-protein ligase WWP1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q13

mRNA and Protein(s)

mRNA	Protein	Name
NM_001024757.1	NP_001019928.1	NEDD4-like E3 ubiquitin-protein ligase WWP1
XM_006237930.3	XP_006237992.1	NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1
XM_006237931.3	XP_006237993.1	NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X2
XM_008763591.2	XP_008761813.1	NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X3

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009074	XP_319824.3
Homo sapiens (human)	WWP1	NP_008944.1
Pan troglodytes (chimpanzee)	WWP1	XP_519843.2
Drosophila melanogaster (fruit fly)	Su(dx)	NP_722754.1
	WWP1	XP_001083173.1
Bos taurus (cattle)	WWP1	NP_001032540.1
Mus musculus (house mouse)	Wwp1	NP_796301.2
Rattus norvegicus (Norway rat)	Wwp1	NP_001019928.1
Caenorhabditis elegans (roundworm)	wwp-1	NP_740775.1
Xenopus tropicalis (tropical clawed frog)	wwp1	NP_001090844.1
Canis lupus familiaris (dog)	WWP1	XP_003640065.1
Gallus gallus (chicken)	WWP1	NP_001012572.1

Gene Ontology
Bibliography

Related articles in PubMed

WW domain containing E3 ubiquitin protein ligase 1 targets the full-length ErbB4 for ubiquitin-mediated degradation in breast cancer.
Li Y, Zhou Z, Alimandi M, Chen C
Oncogene28(33)2948-58(2009 Aug)

The E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradation.
Feng SM, Muraoka-Cook RS, Hunter D, Sandahl MA, Caskey LS, Miyazawa K, Atfi A, Earp HS 3rd
Molecular and cellular biology29(3)892-906(2009 Feb)

The Nedd4-like family of E3 ubiquitin ligases and cancer.
Chen C, Matesic LE
Cancer metastasis reviews26(3-4)587-604(2007 Dec)

Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3.
Jones DC, Wein MN, Oukka M, Hofstaetter JG, Glimcher MJ, Glimcher LH
Science (New York, N.Y.)312(5777)1223-7(2006 May)

Identification of new partners of the epithelial sodium channel alpha subunit.
Malbert-Colas L, Nicolas G, Galand C, Lecomte MC, Dhermy D
Comptes rendus biologies326(7)615-24(2003 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Wwp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Wwp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa06582	NM_001024757.1 Latest version!	Rattus norvegicus WW domain containing E3 ubiquitin protein ligase 1 (Wwp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$475.30 $679.00
ORa06582	XM_006237931.3 Latest version!	Rattus norvegicus WW domain containing E3 ubiquitin protein ligase 1 (Wwp1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$475.30 $679.00
ORa45481	XM_008763591.2 Latest version!	Rattus norvegicus WW domain containing E3 ubiquitin protein ligase 1 (Wwp1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa28067	XM_006237930.3 Latest version!	Rattus norvegicus WW domain containing E3 ubiquitin protein ligase 1 (Wwp1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Wwp1 ( NM_001024757.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001019928.1 Rattus norvegicus WW domain containing E3 ubiquitin protein ligase 1 (Wwp1), mRNA.

Price & Availability↑

CloneID	ORa06582
Clone ID Related Accession (Same CDS sequence)	NM_001024757.1 , XM_006237931.3
Accession Version	NM_001024757.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2757bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	NEDD4-like E3 ubiquitin-protein ligase WWP1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC097386.1. On Jun 10, 2005 this sequence version replaced XM_216361.3. ##Evidence-Data-START## Transcript exon combination :: BC097386.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCCACTG CTTCACCAAG ATCTGACACT AGTGATAACC ACAGTGGAAG GTTACAGTTA 
AAGGTAACAG TTTCTAGTGC CAAACTAAAA AGAAAAAAGA ACTGGTTTGG AACAGCAATA 
TATACTGAAG TCATAGTAGA TGGAGAAATT AAGAAAACAG CAAAATCCAG TAGTTCTTCT 
AATCCAAAAT GGGATGAGCA GCTGATTGTA AATGTGGCCC CACAGACCAC CTTGGAGTTC 
CGAGTTTGGA GTCATCACAC TTTAAAGGCA GACGCTCTAT TAGGAAAAGC AACAGTGGAC 
TTGAAACAAG TGCTGTTAAC ACACAACAGA AAATTAGAAA AAGTGAAAGA ACAACTAAAA 
CTTTCCTTGG AAAACAAGAA TGGAATAGTA CAAACTGGGG AACTGACAGT TGTCCTTGAT 
GGATTAGTGA TTGAGCCAGA AGCTGTGACA AACCGCAGCT CCTCGCCACC CATAGAAATT 
CAGCAGAATG GGGATGCTGT CCATGAGAAT GGAGACCCTT TGACAAGGAC AACTCCCAGG 
TTGGCTGTTG AAGGTACTAT TGGAATTGAT AATCATGTAT CAACAAGTAC TGTTGTTCCG 
AGCTCATGCT GTTCACATAT AGTTAATGGA GAAAACACAC CTTCATCCCC GCCTCAGGTT 
GCTACCAGAC CCCAAAATAC TCCAGCTCCA AAACCACTCA CGTCTGAGCC CACCAGTGAC 
ACAGTTAATG GAGAATCATC ATCTGTCCTA GCTGATAGTA CTTCAGCCAT GGGTACTTCA 
CTACCATCTG AAGACTCCAC CTCGACTTCC AATTGCACTA GCACCACCGT CCAAGAGCCT 
CCTGTACAAG AACCCCCAGC ATCCTCAGAA CACAGTGAAT GTATTCCCTC TGCCAGTGCA 
GAAGTGGGAC CAGAAGCTCG GAGCCTCATA GACCCTGACT CTGATTCTAG AAATAATTCT 
GGTTTTGACA AAGTAAGGCA GCCAGAAGGG TGTGTGGAAC CTCTCCGGCC ACAGTCGGGA 
AATACCAACA CAGAATCTTT GCCATCAGGG TGGGAACAGA GAAAAGATCC TCATGGTAGA 
ACCTATTATG TGGATCATAA TACTCGAACT ACTACATGGG AAAGACCACA ACCTTTGCCC 
CCAGGTTGGG AAAGAAGGGT TGATGATCGT GGAAGAGTTT ATTATGTGGA TCATAACACC 
AGAACAACAA CCTGGCAGCG ACCTACCATG GAGTCTGTTC GGAATTTTGA ACAGTGGCAG 
TCTCAGCGGA ATCAATTGCA GGGAGCTATG CAACAATTCA ACCAACGATA CCTCTATTCG 
GCTTCAATGT TAGCTGCAGA AAATGACCCA TATGGACCCT TACCACCAGG CTGGGAAAAA 
AGAGTGGATT CAACAGACAG AGTTTACTTT GTGAATCATA ATACAAAAAC AACCCAGTGG 
GAAGATCCAA GAACTCAAGG GTTACCAAAT GAAGAACCCC TCCCAGAAGG CTGGGAAATT 
AGGTATACTC GGGAAGGTGT CAGGTACTTT GTTGACCATA ACACAAGAAC AACAACATTC 
AAAGATCCCC GCAATGGGAA GTCATCGGTA ACTAAAGGTG GTCCGCAGAT CGCTTATGAG 
CGCAGCTTTA GGTGGAAACT GGCCCACTTC CGTTACTTGT GCCAGTCTAA TGCACTACCC 
AGTCATGTAA AGATCAATGT GTCCCGACAG ACATTATTTG AAGATTCCTT TCAACAGATT 
ATGGCATTAA AACCGTATGA CTTGAGGAGG CGATTATATG TAATATTTAG AGGAGAAGAA 
GGCCTCGATT ATGGTGGCCT TGCAAGAGAA TGGTTTTTCT TGCTTTCCCA TGAAGTTTTG 
AACCCAATGT ATTGCTTATT TGAGTATGCA GGCAAGAATA ACTATTGTTT ACAGATAAAC 
CCAGCGTCAA CTATAAATCC TGATCATCTT TCATACTTCT GTTTTATTGG TCGCTTTATT 
GCAATGGCGC TATTCCACGG AAAGTTTATT GATACTGGTT TTTCTTTACC ATTCTACAAG 
CGTATGCTAA GTAAAAAACT TACTATCAAG GATTTGGAAT CTATCGATAC TGAATTTTAC 
AATTCTCTAA TCTGGATAAG AGATAACAAT ATTGAAGAAT GTGGCTTAGA AATGTACTTT 
TCTGTAGACA TGGAGATTCT GGGAAAAGTT ACTTCACATG ATTTAAAGTT GGGAGGTTCC 
AATATCCTGG TGACTGAAGA AAACAAAGAT GAATATATTG GTTTAATGAC AGAATGGCGT 
TTTTCACGAG GAGTACAAGA GCAGACCAAA GCTTTCCTTG ATGGGTTTAA TGAAGTTGTC 
CCCCTTCAGT GGCTACAGTA CTTTGATGAA AAAGAATTGG AGGTTATGCT GTGTGGCATG 
CAAGAGGTTG ACCTGGCAGA CTGGCAGAGA AACACTGTTT ACCGACATTA CACGAGAAAC 
AGCAAGCAGA TTATTTGGTT TTGGCAGTTT GTGAAAGAGA CTGATAATGA AGTACGAATG 
CGACTCCTGC AGTTCGTCAC TGGAACCTGT CGCTTGCCTC TAGGAGGATT TGCTGAGCTC 
ATGGGAAGTA ATGGGCCTCA AAAATTCTGT ATTGAAAAAG TTGGCAAAGA CACCTGGTTA 
CCAAGAAGCC ATACATGTTT TAATCGCTTG GATCTACCAC CATATAAGAG TTATGAACAA 
CTAAAGGAAA AACTTCTTTT TGCAATAGAA GAGACAGAGG GATTTGGACA AGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019928.1
CDS	257..3013
Translation	MATASPRSDTSDNHSGRLQLKVTVSSAKLKRKKNWFGTAIYTEVIVDGEIKKTAKSSSSSNPKWDEQLIVNVAPQTTLEFRVWSHHTLKADALLGKATVDLKQVLLTHNRKLEKVKEQLKLSLENKNGIVQTGELTVVLDGLVIEPEAVTNRSSSPPIEIQQNGDAVHENGDPLTRTTPRLAVEGTIGIDNHVSTSTVVPSSCCSHIVNGENTPSSPPQVATRPQNTPAPKPLTSEPTSDTVNGESSSVLADSTSAMGTSLPSEDSTSTSNCTSTTVQEPPVQEPPASSEHSECIPSASAEVGPEARSLIDPDSDSRNNSGFDKVRQPEGCVEPLRPQSGNTNTESLPSGWEQRKDPHGRTYYVDHNTRTTTWERPQPLPPGWERRVDDRGRVYYVDHNTRTTTWQRPTMESVRNFEQWQSQRNQLQGAMQQFNQRYLYSASMLAAENDPYGPLPPGWEKRVDSTDRVYFVNHNTKTTQWEDPRTQGLPNEEPLPEGWEIRYTREGVRYFVDHNTRTTTFKDPRNGKSSVTKGGPQIAYERSFRWKLAHFRYLCQSNALPSHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE

Target ORF information:

RefSeq Version	NM_001024757.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus WW domain containing E3 ubiquitin protein ligase 1 (Wwp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024757.1

ORF Insert Sequence:

ATGGCCACTG CTTCACCAAG ATCTGACACT AGTGATAACC ACAGTGGAAG GTTACAGTTA 
AAGGTAACAG TTTCTAGTGC CAAACTAAAA AGAAAAAAGA ACTGGTTTGG AACAGCAATA 
TATACTGAAG TCATAGTAGA TGGAGAAATT AAGAAAACAG CAAAATCCAG TAGTTCTTCT 
AATCCAAAAT GGGATGAGCA GCTGATTGTA AATGTGGCCC CACAGACCAC CTTGGAGTTC 
CGAGTTTGGA GTCATCACAC TTTAAAGGCA GACGCTCTAT TAGGAAAAGC AACAGTGGAC 
TTGAAACAAG TGCTGTTAAC ACACAACAGA AAATTAGAAA AAGTGAAAGA ACAACTAAAA 
CTTTCCTTGG AAAACAAGAA TGGAATAGTA CAAACTGGGG AACTGACAGT TGTCCTTGAT 
GGATTAGTGA TTGAGCCAGA AGCTGTGACA AACCGCAGCT CCTCGCCACC CATAGAAATT 
CAGCAGAATG GGGATGCTGT CCATGAGAAT GGAGACCCTT TGACAAGGAC AACTCCCAGG 
TTGGCTGTTG AAGGTACTAT TGGAATTGAT AATCATGTAT CAACAAGTAC TGTTGTTCCG 
AGCTCATGCT GTTCACATAT AGTTAATGGA GAAAACACAC CTTCATCCCC GCCTCAGGTT 
GCTACCAGAC CCCAAAATAC TCCAGCTCCA AAACCACTCA CGTCTGAGCC CACCAGTGAC 
ACAGTTAATG GAGAATCATC ATCTGTCCTA GCTGATAGTA CTTCAGCCAT GGGTACTTCA 
CTACCATCTG AAGACTCCAC CTCGACTTCC AATTGCACTA GCACCACCGT CCAAGAGCCT 
CCTGTACAAG AACCCCCAGC ATCCTCAGAA CACAGTGAAT GTATTCCCTC TGCCAGTGCA 
GAAGTGGGAC CAGAAGCTCG GAGCCTCATA GACCCTGACT CTGATTCTAG AAATAATTCT 
GGTTTTGACA AAGTAAGGCA GCCAGAAGGG TGTGTGGAAC CTCTCCGGCC ACAGTCGGGA 
AATACCAACA CAGAATCTTT GCCATCAGGG TGGGAACAGA GAAAAGATCC TCATGGTAGA 
ACCTATTATG TGGATCATAA TACTCGAACT ACTACATGGG AAAGACCACA ACCTTTGCCC 
CCAGGTTGGG AAAGAAGGGT TGATGATCGT GGAAGAGTTT ATTATGTGGA TCATAACACC 
AGAACAACAA CCTGGCAGCG ACCTACCATG GAGTCTGTTC GGAATTTTGA ACAGTGGCAG 
TCTCAGCGGA ATCAATTGCA GGGAGCTATG CAACAATTCA ACCAACGATA CCTCTATTCG 
GCTTCAATGT TAGCTGCAGA AAATGACCCA TATGGACCCT TACCACCAGG CTGGGAAAAA 
AGAGTGGATT CAACAGACAG AGTTTACTTT GTGAATCATA ATACAAAAAC AACCCAGTGG 
GAAGATCCAA GAACTCAAGG GTTACCAAAT GAAGAACCCC TCCCAGAAGG CTGGGAAATT 
AGGTATACTC GGGAAGGTGT CAGGTACTTT GTTGACCATA ACACAAGAAC AACAACATTC 
AAAGATCCCC GCAATGGGAA GTCATCGGTA ACTAAAGGTG GTCCGCAGAT CGCTTATGAG 
CGCAGCTTTA GGTGGAAACT GGCCCACTTC CGTTACTTGT GCCAGTCTAA TGCACTACCC 
AGTCATGTAA AGATCAATGT GTCCCGACAG ACATTATTTG AAGATTCCTT TCAACAGATT 
ATGGCATTAA AACCGTATGA CTTGAGGAGG CGATTATATG TAATATTTAG AGGAGAAGAA 
GGCCTCGATT ATGGTGGCCT TGCAAGAGAA TGGTTTTTCT TGCTTTCCCA TGAAGTTTTG 
AACCCAATGT ATTGCTTATT TGAGTATGCA GGCAAGAATA ACTATTGTTT ACAGATAAAC 
CCAGCGTCAA CTATAAATCC TGATCATCTT TCATACTTCT GTTTTATTGG TCGCTTTATT 
GCAATGGCGC TATTCCACGG AAAGTTTATT GATACTGGTT TTTCTTTACC ATTCTACAAG 
CGTATGCTAA GTAAAAAACT TACTATCAAG GATTTGGAAT CTATCGATAC TGAATTTTAC 
AATTCTCTAA TCTGGATAAG AGATAACAAT ATTGAAGAAT GTGGCTTAGA AATGTACTTT 
TCTGTAGACA TGGAGATTCT GGGAAAAGTT ACTTCACATG ATTTAAAGTT GGGAGGTTCC 
AATATCCTGG TGACTGAAGA AAACAAAGAT GAATATATTG GTTTAATGAC AGAATGGCGT 
TTTTCACGAG GAGTACAAGA GCAGACCAAA GCTTTCCTTG ATGGGTTTAA TGAAGTTGTC 
CCCCTTCAGT GGCTACAGTA CTTTGATGAA AAAGAATTGG AGGTTATGCT GTGTGGCATG 
CAAGAGGTTG ACCTGGCAGA CTGGCAGAGA AACACTGTTT ACCGACATTA CACGAGAAAC 
AGCAAGCAGA TTATTTGGTT TTGGCAGTTT GTGAAAGAGA CTGATAATGA AGTACGAATG 
CGACTCCTGC AGTTCGTCAC TGGAACCTGT CGCTTGCCTC TAGGAGGATT TGCTGAGCTC 
ATGGGAAGTA ATGGGCCTCA AAAATTCTGT ATTGAAAAAG TTGGCAAAGA CACCTGGTTA 
CCAAGAAGCC ATACATGTTT TAATCGCTTG GATCTACCAC CATATAAGAG TTATGAACAA 
CTAAAGGAAA AACTTCTTTT TGCAATAGAA GAGACAGAGG GATTTGGACA AGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Wwp1 ( XM_006237931.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006237993.1 Rattus norvegicus WW domain containing E3 ubiquitin protein ligase 1 (Wwp1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa06582
Clone ID Related Accession (Same CDS sequence)	NM_001024757.1 , XM_006237931.3
Accession Version	XM_006237931.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2757bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006237931.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCACTG CTTCACCAAG ATCTGACACT AGTGATAACC ACAGTGGAAG GTTACAGTTA 
AAGGTAACAG TTTCTAGTGC CAAACTAAAA AGAAAAAAGA ACTGGTTTGG AACAGCAATA 
TATACTGAAG TCATAGTAGA TGGAGAAATT AAGAAAACAG CAAAATCCAG TAGTTCTTCT 
AATCCAAAAT GGGATGAGCA GCTGATTGTA AATGTGGCCC CACAGACCAC CTTGGAGTTC 
CGAGTTTGGA GTCATCACAC TTTAAAGGCA GACGCTCTAT TAGGAAAAGC AACAGTGGAC 
TTGAAACAAG TGCTGTTAAC ACACAACAGA AAATTAGAAA AAGTGAAAGA ACAACTAAAA 
CTTTCCTTGG AAAACAAGAA TGGAATAGTA CAAACTGGGG AACTGACAGT TGTCCTTGAT 
GGATTAGTGA TTGAGCCAGA AGCTGTGACA AACCGCAGCT CCTCGCCACC CATAGAAATT 
CAGCAGAATG GGGATGCTGT CCATGAGAAT GGAGACCCTT TGACAAGGAC AACTCCCAGG 
TTGGCTGTTG AAGGTACTAT TGGAATTGAT AATCATGTAT CAACAAGTAC TGTTGTTCCG 
AGCTCATGCT GTTCACATAT AGTTAATGGA GAAAACACAC CTTCATCCCC GCCTCAGGTT 
GCTACCAGAC CCCAAAATAC TCCAGCTCCA AAACCACTCA CGTCTGAGCC CACCAGTGAC 
ACAGTTAATG GAGAATCATC ATCTGTCCTA GCTGATAGTA CTTCAGCCAT GGGTACTTCA 
CTACCATCTG AAGACTCCAC CTCGACTTCC AATTGCACTA GCACCACCGT CCAAGAGCCT 
CCTGTACAAG AACCCCCAGC ATCCTCAGAA CACAGTGAAT GTATTCCCTC TGCCAGTGCA 
GAAGTGGGAC CAGAAGCTCG GAGCCTCATA GACCCTGACT CTGATTCTAG AAATAATTCT 
GGTTTTGACA AAGTAAGGCA GCCAGAAGGG TGTGTGGAAC CTCTCCGGCC ACAGTCGGGA 
AATACCAACA CAGAATCTTT GCCATCAGGG TGGGAACAGA GAAAAGATCC TCATGGTAGA 
ACCTATTATG TGGATCATAA TACTCGAACT ACTACATGGG AAAGACCACA ACCTTTGCCC 
CCAGGTTGGG AAAGAAGGGT TGATGATCGT GGAAGAGTTT ATTATGTGGA TCATAACACC 
AGAACAACAA CCTGGCAGCG ACCTACCATG GAGTCTGTTC GGAATTTTGA ACAGTGGCAG 
TCTCAGCGGA ATCAATTGCA GGGAGCTATG CAACAATTCA ACCAACGATA CCTCTATTCG 
GCTTCAATGT TAGCTGCAGA AAATGACCCA TATGGACCCT TACCACCAGG CTGGGAAAAA 
AGAGTGGATT CAACAGACAG AGTTTACTTT GTGAATCATA ATACAAAAAC AACCCAGTGG 
GAAGATCCAA GAACTCAAGG GTTACCAAAT GAAGAACCCC TCCCAGAAGG CTGGGAAATT 
AGGTATACTC GGGAAGGTGT CAGGTACTTT GTTGACCATA ACACAAGAAC AACAACATTC 
AAAGATCCCC GCAATGGGAA GTCATCGGTA ACTAAAGGTG GTCCGCAGAT CGCTTATGAG 
CGCAGCTTTA GGTGGAAACT GGCCCACTTC CGTTACTTGT GCCAGTCTAA TGCACTACCC 
AGTCATGTAA AGATCAATGT GTCCCGACAG ACATTATTTG AAGATTCCTT TCAACAGATT 
ATGGCATTAA AACCGTATGA CTTGAGGAGG CGATTATATG TAATATTTAG AGGAGAAGAA 
GGCCTCGATT ATGGTGGCCT TGCAAGAGAA TGGTTTTTCT TGCTTTCCCA TGAAGTTTTG 
AACCCAATGT ATTGCTTATT TGAGTATGCA GGCAAGAATA ACTATTGTTT ACAGATAAAC 
CCAGCGTCAA CTATAAATCC TGATCATCTT TCATACTTCT GTTTTATTGG TCGCTTTATT 
GCAATGGCGC TATTCCACGG AAAGTTTATT GATACTGGTT TTTCTTTACC ATTCTACAAG 
CGTATGCTAA GTAAAAAACT TACTATCAAG GATTTGGAAT CTATCGATAC TGAATTTTAC 
AATTCTCTAA TCTGGATAAG AGATAACAAT ATTGAAGAAT GTGGCTTAGA AATGTACTTT 
TCTGTAGACA TGGAGATTCT GGGAAAAGTT ACTTCACATG ATTTAAAGTT GGGAGGTTCC 
AATATCCTGG TGACTGAAGA AAACAAAGAT GAATATATTG GTTTAATGAC AGAATGGCGT 
TTTTCACGAG GAGTACAAGA GCAGACCAAA GCTTTCCTTG ATGGGTTTAA TGAAGTTGTC 
CCCCTTCAGT GGCTACAGTA CTTTGATGAA AAAGAATTGG AGGTTATGCT GTGTGGCATG 
CAAGAGGTTG ACCTGGCAGA CTGGCAGAGA AACACTGTTT ACCGACATTA CACGAGAAAC 
AGCAAGCAGA TTATTTGGTT TTGGCAGTTT GTGAAAGAGA CTGATAATGA AGTACGAATG 
CGACTCCTGC AGTTCGTCAC TGGAACCTGT CGCTTGCCTC TAGGAGGATT TGCTGAGCTC 
ATGGGAAGTA ATGGGCCTCA AAAATTCTGT ATTGAAAAAG TTGGCAAAGA CACCTGGTTA 
CCAAGAAGCC ATACATGTTT TAATCGCTTG GATCTACCAC CATATAAGAG TTATGAACAA 
CTAAAGGAAA AACTTCTTTT TGCAATAGAA GAGACAGAGG GATTTGGACA AGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006237993.1
CDS	599..3355
Translation	MATASPRSDTSDNHSGRLQLKVTVSSAKLKRKKNWFGTAIYTEVIVDGEIKKTAKSSSSSNPKWDEQLIVNVAPQTTLEFRVWSHHTLKADALLGKATVDLKQVLLTHNRKLEKVKEQLKLSLENKNGIVQTGELTVVLDGLVIEPEAVTNRSSSPPIEIQQNGDAVHENGDPLTRTTPRLAVEGTIGIDNHVSTSTVVPSSCCSHIVNGENTPSSPPQVATRPQNTPAPKPLTSEPTSDTVNGESSSVLADSTSAMGTSLPSEDSTSTSNCTSTTVQEPPVQEPPASSEHSECIPSASAEVGPEARSLIDPDSDSRNNSGFDKVRQPEGCVEPLRPQSGNTNTESLPSGWEQRKDPHGRTYYVDHNTRTTTWERPQPLPPGWERRVDDRGRVYYVDHNTRTTTWQRPTMESVRNFEQWQSQRNQLQGAMQQFNQRYLYSASMLAAENDPYGPLPPGWEKRVDSTDRVYFVNHNTKTTQWEDPRTQGLPNEEPLPEGWEIRYTREGVRYFVDHNTRTTTFKDPRNGKSSVTKGGPQIAYERSFRWKLAHFRYLCQSNALPSHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE

Target ORF information:

RefSeq Version	XM_006237931.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus WW domain containing E3 ubiquitin protein ligase 1 (Wwp1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006237931.3

ORF Insert Sequence:

ATGGCCACTG CTTCACCAAG ATCTGACACT AGTGATAACC ACAGTGGAAG GTTACAGTTA 
AAGGTAACAG TTTCTAGTGC CAAACTAAAA AGAAAAAAGA ACTGGTTTGG AACAGCAATA 
TATACTGAAG TCATAGTAGA TGGAGAAATT AAGAAAACAG CAAAATCCAG TAGTTCTTCT 
AATCCAAAAT GGGATGAGCA GCTGATTGTA AATGTGGCCC CACAGACCAC CTTGGAGTTC 
CGAGTTTGGA GTCATCACAC TTTAAAGGCA GACGCTCTAT TAGGAAAAGC AACAGTGGAC 
TTGAAACAAG TGCTGTTAAC ACACAACAGA AAATTAGAAA AAGTGAAAGA ACAACTAAAA 
CTTTCCTTGG AAAACAAGAA TGGAATAGTA CAAACTGGGG AACTGACAGT TGTCCTTGAT 
GGATTAGTGA TTGAGCCAGA AGCTGTGACA AACCGCAGCT CCTCGCCACC CATAGAAATT 
CAGCAGAATG GGGATGCTGT CCATGAGAAT GGAGACCCTT TGACAAGGAC AACTCCCAGG 
TTGGCTGTTG AAGGTACTAT TGGAATTGAT AATCATGTAT CAACAAGTAC TGTTGTTCCG 
AGCTCATGCT GTTCACATAT AGTTAATGGA GAAAACACAC CTTCATCCCC GCCTCAGGTT 
GCTACCAGAC CCCAAAATAC TCCAGCTCCA AAACCACTCA CGTCTGAGCC CACCAGTGAC 
ACAGTTAATG GAGAATCATC ATCTGTCCTA GCTGATAGTA CTTCAGCCAT GGGTACTTCA 
CTACCATCTG AAGACTCCAC CTCGACTTCC AATTGCACTA GCACCACCGT CCAAGAGCCT 
CCTGTACAAG AACCCCCAGC ATCCTCAGAA CACAGTGAAT GTATTCCCTC TGCCAGTGCA 
GAAGTGGGAC CAGAAGCTCG GAGCCTCATA GACCCTGACT CTGATTCTAG AAATAATTCT 
GGTTTTGACA AAGTAAGGCA GCCAGAAGGG TGTGTGGAAC CTCTCCGGCC ACAGTCGGGA 
AATACCAACA CAGAATCTTT GCCATCAGGG TGGGAACAGA GAAAAGATCC TCATGGTAGA 
ACCTATTATG TGGATCATAA TACTCGAACT ACTACATGGG AAAGACCACA ACCTTTGCCC 
CCAGGTTGGG AAAGAAGGGT TGATGATCGT GGAAGAGTTT ATTATGTGGA TCATAACACC 
AGAACAACAA CCTGGCAGCG ACCTACCATG GAGTCTGTTC GGAATTTTGA ACAGTGGCAG 
TCTCAGCGGA ATCAATTGCA GGGAGCTATG CAACAATTCA ACCAACGATA CCTCTATTCG 
GCTTCAATGT TAGCTGCAGA AAATGACCCA TATGGACCCT TACCACCAGG CTGGGAAAAA 
AGAGTGGATT CAACAGACAG AGTTTACTTT GTGAATCATA ATACAAAAAC AACCCAGTGG 
GAAGATCCAA GAACTCAAGG GTTACCAAAT GAAGAACCCC TCCCAGAAGG CTGGGAAATT 
AGGTATACTC GGGAAGGTGT CAGGTACTTT GTTGACCATA ACACAAGAAC AACAACATTC 
AAAGATCCCC GCAATGGGAA GTCATCGGTA ACTAAAGGTG GTCCGCAGAT CGCTTATGAG 
CGCAGCTTTA GGTGGAAACT GGCCCACTTC CGTTACTTGT GCCAGTCTAA TGCACTACCC 
AGTCATGTAA AGATCAATGT GTCCCGACAG ACATTATTTG AAGATTCCTT TCAACAGATT 
ATGGCATTAA AACCGTATGA CTTGAGGAGG CGATTATATG TAATATTTAG AGGAGAAGAA 
GGCCTCGATT ATGGTGGCCT TGCAAGAGAA TGGTTTTTCT TGCTTTCCCA TGAAGTTTTG 
AACCCAATGT ATTGCTTATT TGAGTATGCA GGCAAGAATA ACTATTGTTT ACAGATAAAC 
CCAGCGTCAA CTATAAATCC TGATCATCTT TCATACTTCT GTTTTATTGG TCGCTTTATT 
GCAATGGCGC TATTCCACGG AAAGTTTATT GATACTGGTT TTTCTTTACC ATTCTACAAG 
CGTATGCTAA GTAAAAAACT TACTATCAAG GATTTGGAAT CTATCGATAC TGAATTTTAC 
AATTCTCTAA TCTGGATAAG AGATAACAAT ATTGAAGAAT GTGGCTTAGA AATGTACTTT 
TCTGTAGACA TGGAGATTCT GGGAAAAGTT ACTTCACATG ATTTAAAGTT GGGAGGTTCC 
AATATCCTGG TGACTGAAGA AAACAAAGAT GAATATATTG GTTTAATGAC AGAATGGCGT 
TTTTCACGAG GAGTACAAGA GCAGACCAAA GCTTTCCTTG ATGGGTTTAA TGAAGTTGTC 
CCCCTTCAGT GGCTACAGTA CTTTGATGAA AAAGAATTGG AGGTTATGCT GTGTGGCATG 
CAAGAGGTTG ACCTGGCAGA CTGGCAGAGA AACACTGTTT ACCGACATTA CACGAGAAAC 
AGCAAGCAGA TTATTTGGTT TTGGCAGTTT GTGAAAGAGA CTGATAATGA AGTACGAATG 
CGACTCCTGC AGTTCGTCAC TGGAACCTGT CGCTTGCCTC TAGGAGGATT TGCTGAGCTC 
ATGGGAAGTA ATGGGCCTCA AAAATTCTGT ATTGAAAAAG TTGGCAAAGA CACCTGGTTA 
CCAAGAAGCC ATACATGTTT TAATCGCTTG GATCTACCAC CATATAAGAG TTATGAACAA 
CTAAAGGAAA AACTTCTTTT TGCAATAGAA GAGACAGAGG GATTTGGACA AGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Wwp1 ( XM_008763591.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008761813.1 Rattus norvegicus WW domain containing E3 ubiquitin protein ligase 1 (Wwp1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa45481
Clone ID Related Accession (Same CDS sequence)	XM_008763591.2
Accession Version	XM_008763591.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1989bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008763591.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTACTT CACTACCATC TGAAGACTCC ACCTCGACTT CCAATTGCAC TAGCACCACC 
GTCCAAGAGC CTCCTGTACA AGAACCCCCA GCATCCTCAG AACACAGTGA ATGTATTCCC 
TCTGCCAGTG CAGAAGTGGG ACCAGAAGCT CGGAGCCTCA TAGACCCTGA CTCTGATTCT 
AGAAATAATT CTGGTTTTGA CAAAGTAAGG CAGCCAGAAG GGTGTGTGGA ACCTCTCCGG 
CCACAGTCGG GAAATACCAA CACAGAATCT TTGCCATCAG GGTGGGAACA GAGAAAAGAT 
CCTCATGGTA GAACCTATTA TGTGGATCAT AATACTCGAA CTACTACATG GGAAAGACCA 
CAACCTTTGC CCCCAGGTTG GGAAAGAAGG GTTGATGATC GTGGAAGAGT TTATTATGTG 
GATCATAACA CCAGAACAAC AACCTGGCAG CGACCTACCA TGGAGTCTGT TCGGAATTTT 
GAACAGTGGC AGTCTCAGCG GAATCAATTG CAGGGAGCTA TGCAACAATT CAACCAACGA 
TACCTCTATT CGGCTTCAAT GTTAGCTGCA GAAAATGACC CATATGGACC CTTACCACCA 
GGCTGGGAAA AAAGAGTGGA TTCAACAGAC AGAGTTTACT TTGTGAATCA TAATACAAAA 
ACAACCCAGT GGGAAGATCC AAGAACTCAA GGGTTACCAA ATGAAGAACC CCTCCCAGAA 
GGCTGGGAAA TTAGGTATAC TCGGGAAGGT GTCAGGTACT TTGTTGACCA TAACACAAGA 
ACAACAACAT TCAAAGATCC CCGCAATGGG AAGTCATCGG TAACTAAAGG TGGTCCGCAG 
ATCGCTTATG AGCGCAGCTT TAGGTGGAAA CTGGCCCACT TCCGTTACTT GTGCCAGTCT 
AATGCACTAC CCAGTCATGT AAAGATCAAT GTGTCCCGAC AGACATTATT TGAAGATTCC 
TTTCAACAGA TTATGGCATT AAAACCGTAT GACTTGAGGA GGCGATTATA TGTAATATTT 
AGAGGAGAAG AAGGCCTCGA TTATGGTGGC CTTGCAAGAG AATGGTTTTT CTTGCTTTCC 
CATGAAGTTT TGAACCCAAT GTATTGCTTA TTTGAGTATG CAGGCAAGAA TAACTATTGT 
TTACAGATAA ACCCAGCGTC AACTATAAAT CCTGATCATC TTTCATACTT CTGTTTTATT 
GGTCGCTTTA TTGCAATGGC GCTATTCCAC GGAAAGTTTA TTGATACTGG TTTTTCTTTA 
CCATTCTACA AGCGTATGCT AAGTAAAAAA CTTACTATCA AGGATTTGGA ATCTATCGAT 
ACTGAATTTT ACAATTCTCT AATCTGGATA AGAGATAACA ATATTGAAGA ATGTGGCTTA 
GAAATGTACT TTTCTGTAGA CATGGAGATT CTGGGAAAAG TTACTTCACA TGATTTAAAG 
TTGGGAGGTT CCAATATCCT GGTGACTGAA GAAAACAAAG ATGAATATAT TGGTTTAATG 
ACAGAATGGC GTTTTTCACG AGGAGTACAA GAGCAGACCA AAGCTTTCCT TGATGGGTTT 
AATGAAGTTG TCCCCCTTCA GTGGCTACAG TACTTTGATG AAAAAGAATT GGAGGTTATG 
CTGTGTGGCA TGCAAGAGGT TGACCTGGCA GACTGGCAGA GAAACACTGT TTACCGACAT 
TACACGAGAA ACAGCAAGCA GATTATTTGG TTTTGGCAGT TTGTGAAAGA GACTGATAAT 
GAAGTACGAA TGCGACTCCT GCAGTTCGTC ACTGGAACCT GTCGCTTGCC TCTAGGAGGA 
TTTGCTGAGC TCATGGGAAG TAATGGGCCT CAAAAATTCT GTATTGAAAA AGTTGGCAAA 
GACACCTGGT TACCAAGAAG CCATACATGT TTTAATCGCT TGGATCTACC ACCATATAAG 
AGTTATGAAC AACTAAAGGA AAAACTTCTT TTTGCAATAG AAGAGACAGA GGGATTTGGA 
CAAGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008761813.1
CDS	269..2257
Translation	MGTSLPSEDSTSTSNCTSTTVQEPPVQEPPASSEHSECIPSASAEVGPEARSLIDPDSDSRNNSGFDKVRQPEGCVEPLRPQSGNTNTESLPSGWEQRKDPHGRTYYVDHNTRTTTWERPQPLPPGWERRVDDRGRVYYVDHNTRTTTWQRPTMESVRNFEQWQSQRNQLQGAMQQFNQRYLYSASMLAAENDPYGPLPPGWEKRVDSTDRVYFVNHNTKTTQWEDPRTQGLPNEEPLPEGWEIRYTREGVRYFVDHNTRTTTFKDPRNGKSSVTKGGPQIAYERSFRWKLAHFRYLCQSNALPSHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE

Target ORF information:

RefSeq Version	XM_008763591.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus WW domain containing E3 ubiquitin protein ligase 1 (Wwp1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008763591.2

ORF Insert Sequence:

ATGGGTACTT CACTACCATC TGAAGACTCC ACCTCGACTT CCAATTGCAC TAGCACCACC 
GTCCAAGAGC CTCCTGTACA AGAACCCCCA GCATCCTCAG AACACAGTGA ATGTATTCCC 
TCTGCCAGTG CAGAAGTGGG ACCAGAAGCT CGGAGCCTCA TAGACCCTGA CTCTGATTCT 
AGAAATAATT CTGGTTTTGA CAAAGTAAGG CAGCCAGAAG GGTGTGTGGA ACCTCTCCGG 
CCACAGTCGG GAAATACCAA CACAGAATCT TTGCCATCAG GGTGGGAACA GAGAAAAGAT 
CCTCATGGTA GAACCTATTA TGTGGATCAT AATACTCGAA CTACTACATG GGAAAGACCA 
CAACCTTTGC CCCCAGGTTG GGAAAGAAGG GTTGATGATC GTGGAAGAGT TTATTATGTG 
GATCATAACA CCAGAACAAC AACCTGGCAG CGACCTACCA TGGAGTCTGT TCGGAATTTT 
GAACAGTGGC AGTCTCAGCG GAATCAATTG CAGGGAGCTA TGCAACAATT CAACCAACGA 
TACCTCTATT CGGCTTCAAT GTTAGCTGCA GAAAATGACC CATATGGACC CTTACCACCA 
GGCTGGGAAA AAAGAGTGGA TTCAACAGAC AGAGTTTACT TTGTGAATCA TAATACAAAA 
ACAACCCAGT GGGAAGATCC AAGAACTCAA GGGTTACCAA ATGAAGAACC CCTCCCAGAA 
GGCTGGGAAA TTAGGTATAC TCGGGAAGGT GTCAGGTACT TTGTTGACCA TAACACAAGA 
ACAACAACAT TCAAAGATCC CCGCAATGGG AAGTCATCGG TAACTAAAGG TGGTCCGCAG 
ATCGCTTATG AGCGCAGCTT TAGGTGGAAA CTGGCCCACT TCCGTTACTT GTGCCAGTCT 
AATGCACTAC CCAGTCATGT AAAGATCAAT GTGTCCCGAC AGACATTATT TGAAGATTCC 
TTTCAACAGA TTATGGCATT AAAACCGTAT GACTTGAGGA GGCGATTATA TGTAATATTT 
AGAGGAGAAG AAGGCCTCGA TTATGGTGGC CTTGCAAGAG AATGGTTTTT CTTGCTTTCC 
CATGAAGTTT TGAACCCAAT GTATTGCTTA TTTGAGTATG CAGGCAAGAA TAACTATTGT 
TTACAGATAA ACCCAGCGTC AACTATAAAT CCTGATCATC TTTCATACTT CTGTTTTATT 
GGTCGCTTTA TTGCAATGGC GCTATTCCAC GGAAAGTTTA TTGATACTGG TTTTTCTTTA 
CCATTCTACA AGCGTATGCT AAGTAAAAAA CTTACTATCA AGGATTTGGA ATCTATCGAT 
ACTGAATTTT ACAATTCTCT AATCTGGATA AGAGATAACA ATATTGAAGA ATGTGGCTTA 
GAAATGTACT TTTCTGTAGA CATGGAGATT CTGGGAAAAG TTACTTCACA TGATTTAAAG 
TTGGGAGGTT CCAATATCCT GGTGACTGAA GAAAACAAAG ATGAATATAT TGGTTTAATG 
ACAGAATGGC GTTTTTCACG AGGAGTACAA GAGCAGACCA AAGCTTTCCT TGATGGGTTT 
AATGAAGTTG TCCCCCTTCA GTGGCTACAG TACTTTGATG AAAAAGAATT GGAGGTTATG 
CTGTGTGGCA TGCAAGAGGT TGACCTGGCA GACTGGCAGA GAAACACTGT TTACCGACAT 
TACACGAGAA ACAGCAAGCA GATTATTTGG TTTTGGCAGT TTGTGAAAGA GACTGATAAT 
GAAGTACGAA TGCGACTCCT GCAGTTCGTC ACTGGAACCT GTCGCTTGCC TCTAGGAGGA 
TTTGCTGAGC TCATGGGAAG TAATGGGCCT CAAAAATTCT GTATTGAAAA AGTTGGCAAA 
GACACCTGGT TACCAAGAAG CCATACATGT TTTAATCGCT TGGATCTACC ACCATATAAG 
AGTTATGAAC AACTAAAGGA AAAACTTCTT TTTGCAATAG AAGAGACAGA GGGATTTGGA 
CAAGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Wwp1 ( XM_006237930.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006237992.1 Rattus norvegicus WW domain containing E3 ubiquitin protein ligase 1 (Wwp1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa28067
Clone ID Related Accession (Same CDS sequence)	XM_006237930.3
Accession Version	XM_006237930.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2907bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006237930.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCTCCT TGACAGAAGA AATCGCGTCG TCTTCATCTT CGTATCCTCA GTGTCTGGAA 
CAGTTCCTGG TACACAAGTT CCAGTTTTGG GCCCTTCAAA CTTGTTTCAG TTATTACTCC 
ATCTGTCACA ATCAAGGTGA ATTTTGGGAC ATGGCCACTG CTTCACCAAG ATCTGACACT 
AGTGATAACC ACAGTGGAAG GTTACAGTTA AAGGTAACAG TTTCTAGTGC CAAACTAAAA 
AGAAAAAAGA ACTGGTTTGG AACAGCAATA TATACTGAAG TCATAGTAGA TGGAGAAATT 
AAGAAAACAG CAAAATCCAG TAGTTCTTCT AATCCAAAAT GGGATGAGCA GCTGATTGTA 
AATGTGGCCC CACAGACCAC CTTGGAGTTC CGAGTTTGGA GTCATCACAC TTTAAAGGCA 
GACGCTCTAT TAGGAAAAGC AACAGTGGAC TTGAAACAAG TGCTGTTAAC ACACAACAGA 
AAATTAGAAA AAGTGAAAGA ACAACTAAAA CTTTCCTTGG AAAACAAGAA TGGAATAGTA 
CAAACTGGGG AACTGACAGT TGTCCTTGAT GGATTAGTGA TTGAGCCAGA AGCTGTGACA 
AACCGCAGCT CCTCGCCACC CATAGAAATT CAGCAGAATG GGGATGCTGT CCATGAGAAT 
GGAGACCCTT TGACAAGGAC AACTCCCAGG TTGGCTGTTG AAGGTACTAT TGGAATTGAT 
AATCATGTAT CAACAAGTAC TGTTGTTCCG AGCTCATGCT GTTCACATAT AGTTAATGGA 
GAAAACACAC CTTCATCCCC GCCTCAGGTT GCTACCAGAC CCCAAAATAC TCCAGCTCCA 
AAACCACTCA CGTCTGAGCC CACCAGTGAC ACAGTTAATG GAGAATCATC ATCTGTCCTA 
GCTGATAGTA CTTCAGCCAT GGGTACTTCA CTACCATCTG AAGACTCCAC CTCGACTTCC 
AATTGCACTA GCACCACCGT CCAAGAGCCT CCTGTACAAG AACCCCCAGC ATCCTCAGAA 
CACAGTGAAT GTATTCCCTC TGCCAGTGCA GAAGTGGGAC CAGAAGCTCG GAGCCTCATA 
GACCCTGACT CTGATTCTAG AAATAATTCT GGTTTTGACA AAGTAAGGCA GCCAGAAGGG 
TGTGTGGAAC CTCTCCGGCC ACAGTCGGGA AATACCAACA CAGAATCTTT GCCATCAGGG 
TGGGAACAGA GAAAAGATCC TCATGGTAGA ACCTATTATG TGGATCATAA TACTCGAACT 
ACTACATGGG AAAGACCACA ACCTTTGCCC CCAGGTTGGG AAAGAAGGGT TGATGATCGT 
GGAAGAGTTT ATTATGTGGA TCATAACACC AGAACAACAA CCTGGCAGCG ACCTACCATG 
GAGTCTGTTC GGAATTTTGA ACAGTGGCAG TCTCAGCGGA ATCAATTGCA GGGAGCTATG 
CAACAATTCA ACCAACGATA CCTCTATTCG GCTTCAATGT TAGCTGCAGA AAATGACCCA 
TATGGACCCT TACCACCAGG CTGGGAAAAA AGAGTGGATT CAACAGACAG AGTTTACTTT 
GTGAATCATA ATACAAAAAC AACCCAGTGG GAAGATCCAA GAACTCAAGG GTTACCAAAT 
GAAGAACCCC TCCCAGAAGG CTGGGAAATT AGGTATACTC GGGAAGGTGT CAGGTACTTT 
GTTGACCATA ACACAAGAAC AACAACATTC AAAGATCCCC GCAATGGGAA GTCATCGGTA 
ACTAAAGGTG GTCCGCAGAT CGCTTATGAG CGCAGCTTTA GGTGGAAACT GGCCCACTTC 
CGTTACTTGT GCCAGTCTAA TGCACTACCC AGTCATGTAA AGATCAATGT GTCCCGACAG 
ACATTATTTG AAGATTCCTT TCAACAGATT ATGGCATTAA AACCGTATGA CTTGAGGAGG 
CGATTATATG TAATATTTAG AGGAGAAGAA GGCCTCGATT ATGGTGGCCT TGCAAGAGAA 
TGGTTTTTCT TGCTTTCCCA TGAAGTTTTG AACCCAATGT ATTGCTTATT TGAGTATGCA 
GGCAAGAATA ACTATTGTTT ACAGATAAAC CCAGCGTCAA CTATAAATCC TGATCATCTT 
TCATACTTCT GTTTTATTGG TCGCTTTATT GCAATGGCGC TATTCCACGG AAAGTTTATT 
GATACTGGTT TTTCTTTACC ATTCTACAAG CGTATGCTAA GTAAAAAACT TACTATCAAG 
GATTTGGAAT CTATCGATAC TGAATTTTAC AATTCTCTAA TCTGGATAAG AGATAACAAT 
ATTGAAGAAT GTGGCTTAGA AATGTACTTT TCTGTAGACA TGGAGATTCT GGGAAAAGTT 
ACTTCACATG ATTTAAAGTT GGGAGGTTCC AATATCCTGG TGACTGAAGA AAACAAAGAT 
GAATATATTG GTTTAATGAC AGAATGGCGT TTTTCACGAG GAGTACAAGA GCAGACCAAA 
GCTTTCCTTG ATGGGTTTAA TGAAGTTGTC CCCCTTCAGT GGCTACAGTA CTTTGATGAA 
AAAGAATTGG AGGTTATGCT GTGTGGCATG CAAGAGGTTG ACCTGGCAGA CTGGCAGAGA 
AACACTGTTT ACCGACATTA CACGAGAAAC AGCAAGCAGA TTATTTGGTT TTGGCAGTTT 
GTGAAAGAGA CTGATAATGA AGTACGAATG CGACTCCTGC AGTTCGTCAC TGGAACCTGT 
CGCTTGCCTC TAGGAGGATT TGCTGAGCTC ATGGGAAGTA ATGGGCCTCA AAAATTCTGT 
ATTGAAAAAG TTGGCAAAGA CACCTGGTTA CCAAGAAGCC ATACATGTTT TAATCGCTTG 
GATCTACCAC CATATAAGAG TTATGAACAA CTAAAGGAAA AACTTCTTTT TGCAATAGAA 
GAGACAGAGG GATTTGGACA AGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006237992.1
CDS	101..3007
Translation	MSSLTEEIASSSSSYPQCLEQFLVHKFQFWALQTCFSYYSICHNQGEFWDMATASPRSDTSDNHSGRLQLKVTVSSAKLKRKKNWFGTAIYTEVIVDGEIKKTAKSSSSSNPKWDEQLIVNVAPQTTLEFRVWSHHTLKADALLGKATVDLKQVLLTHNRKLEKVKEQLKLSLENKNGIVQTGELTVVLDGLVIEPEAVTNRSSSPPIEIQQNGDAVHENGDPLTRTTPRLAVEGTIGIDNHVSTSTVVPSSCCSHIVNGENTPSSPPQVATRPQNTPAPKPLTSEPTSDTVNGESSSVLADSTSAMGTSLPSEDSTSTSNCTSTTVQEPPVQEPPASSEHSECIPSASAEVGPEARSLIDPDSDSRNNSGFDKVRQPEGCVEPLRPQSGNTNTESLPSGWEQRKDPHGRTYYVDHNTRTTTWERPQPLPPGWERRVDDRGRVYYVDHNTRTTTWQRPTMESVRNFEQWQSQRNQLQGAMQQFNQRYLYSASMLAAENDPYGPLPPGWEKRVDSTDRVYFVNHNTKTTQWEDPRTQGLPNEEPLPEGWEIRYTREGVRYFVDHNTRTTTFKDPRNGKSSVTKGGPQIAYERSFRWKLAHFRYLCQSNALPSHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE

Target ORF information:

RefSeq Version	XM_006237930.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus WW domain containing E3 ubiquitin protein ligase 1 (Wwp1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006237930.3

ORF Insert Sequence:

ATGAGCTCCT TGACAGAAGA AATCGCGTCG TCTTCATCTT CGTATCCTCA GTGTCTGGAA 
CAGTTCCTGG TACACAAGTT CCAGTTTTGG GCCCTTCAAA CTTGTTTCAG TTATTACTCC 
ATCTGTCACA ATCAAGGTGA ATTTTGGGAC ATGGCCACTG CTTCACCAAG ATCTGACACT 
AGTGATAACC ACAGTGGAAG GTTACAGTTA AAGGTAACAG TTTCTAGTGC CAAACTAAAA 
AGAAAAAAGA ACTGGTTTGG AACAGCAATA TATACTGAAG TCATAGTAGA TGGAGAAATT 
AAGAAAACAG CAAAATCCAG TAGTTCTTCT AATCCAAAAT GGGATGAGCA GCTGATTGTA 
AATGTGGCCC CACAGACCAC CTTGGAGTTC CGAGTTTGGA GTCATCACAC TTTAAAGGCA 
GACGCTCTAT TAGGAAAAGC AACAGTGGAC TTGAAACAAG TGCTGTTAAC ACACAACAGA 
AAATTAGAAA AAGTGAAAGA ACAACTAAAA CTTTCCTTGG AAAACAAGAA TGGAATAGTA 
CAAACTGGGG AACTGACAGT TGTCCTTGAT GGATTAGTGA TTGAGCCAGA AGCTGTGACA 
AACCGCAGCT CCTCGCCACC CATAGAAATT CAGCAGAATG GGGATGCTGT CCATGAGAAT 
GGAGACCCTT TGACAAGGAC AACTCCCAGG TTGGCTGTTG AAGGTACTAT TGGAATTGAT 
AATCATGTAT CAACAAGTAC TGTTGTTCCG AGCTCATGCT GTTCACATAT AGTTAATGGA 
GAAAACACAC CTTCATCCCC GCCTCAGGTT GCTACCAGAC CCCAAAATAC TCCAGCTCCA 
AAACCACTCA CGTCTGAGCC CACCAGTGAC ACAGTTAATG GAGAATCATC ATCTGTCCTA 
GCTGATAGTA CTTCAGCCAT GGGTACTTCA CTACCATCTG AAGACTCCAC CTCGACTTCC 
AATTGCACTA GCACCACCGT CCAAGAGCCT CCTGTACAAG AACCCCCAGC ATCCTCAGAA 
CACAGTGAAT GTATTCCCTC TGCCAGTGCA GAAGTGGGAC CAGAAGCTCG GAGCCTCATA 
GACCCTGACT CTGATTCTAG AAATAATTCT GGTTTTGACA AAGTAAGGCA GCCAGAAGGG 
TGTGTGGAAC CTCTCCGGCC ACAGTCGGGA AATACCAACA CAGAATCTTT GCCATCAGGG 
TGGGAACAGA GAAAAGATCC TCATGGTAGA ACCTATTATG TGGATCATAA TACTCGAACT 
ACTACATGGG AAAGACCACA ACCTTTGCCC CCAGGTTGGG AAAGAAGGGT TGATGATCGT 
GGAAGAGTTT ATTATGTGGA TCATAACACC AGAACAACAA CCTGGCAGCG ACCTACCATG 
GAGTCTGTTC GGAATTTTGA ACAGTGGCAG TCTCAGCGGA ATCAATTGCA GGGAGCTATG 
CAACAATTCA ACCAACGATA CCTCTATTCG GCTTCAATGT TAGCTGCAGA AAATGACCCA 
TATGGACCCT TACCACCAGG CTGGGAAAAA AGAGTGGATT CAACAGACAG AGTTTACTTT 
GTGAATCATA ATACAAAAAC AACCCAGTGG GAAGATCCAA GAACTCAAGG GTTACCAAAT 
GAAGAACCCC TCCCAGAAGG CTGGGAAATT AGGTATACTC GGGAAGGTGT CAGGTACTTT 
GTTGACCATA ACACAAGAAC AACAACATTC AAAGATCCCC GCAATGGGAA GTCATCGGTA 
ACTAAAGGTG GTCCGCAGAT CGCTTATGAG CGCAGCTTTA GGTGGAAACT GGCCCACTTC 
CGTTACTTGT GCCAGTCTAA TGCACTACCC AGTCATGTAA AGATCAATGT GTCCCGACAG 
ACATTATTTG AAGATTCCTT TCAACAGATT ATGGCATTAA AACCGTATGA CTTGAGGAGG 
CGATTATATG TAATATTTAG AGGAGAAGAA GGCCTCGATT ATGGTGGCCT TGCAAGAGAA 
TGGTTTTTCT TGCTTTCCCA TGAAGTTTTG AACCCAATGT ATTGCTTATT TGAGTATGCA 
GGCAAGAATA ACTATTGTTT ACAGATAAAC CCAGCGTCAA CTATAAATCC TGATCATCTT 
TCATACTTCT GTTTTATTGG TCGCTTTATT GCAATGGCGC TATTCCACGG AAAGTTTATT 
GATACTGGTT TTTCTTTACC ATTCTACAAG CGTATGCTAA GTAAAAAACT TACTATCAAG 
GATTTGGAAT CTATCGATAC TGAATTTTAC AATTCTCTAA TCTGGATAAG AGATAACAAT 
ATTGAAGAAT GTGGCTTAGA AATGTACTTT TCTGTAGACA TGGAGATTCT GGGAAAAGTT 
ACTTCACATG ATTTAAAGTT GGGAGGTTCC AATATCCTGG TGACTGAAGA AAACAAAGAT 
GAATATATTG GTTTAATGAC AGAATGGCGT TTTTCACGAG GAGTACAAGA GCAGACCAAA 
GCTTTCCTTG ATGGGTTTAA TGAAGTTGTC CCCCTTCAGT GGCTACAGTA CTTTGATGAA 
AAAGAATTGG AGGTTATGCT GTGTGGCATG CAAGAGGTTG ACCTGGCAGA CTGGCAGAGA 
AACACTGTTT ACCGACATTA CACGAGAAAC AGCAAGCAGA TTATTTGGTT TTGGCAGTTT 
GTGAAAGAGA CTGATAATGA AGTACGAATG CGACTCCTGC AGTTCGTCAC TGGAACCTGT 
CGCTTGCCTC TAGGAGGATT TGCTGAGCTC ATGGGAAGTA ATGGGCCTCA AAAATTCTGT 
ATTGAAAAAG TTGGCAAAGA CACCTGGTTA CCAAGAAGCC ATACATGTTT TAATCGCTTG 
GATCTACCAC CATATAAGAG TTATGAACAA CTAAAGGAAA AACTTCTTTT TGCAATAGAA 
GAGACAGAGG GATTTGGACA AGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

WW domain containing E3 ubiquitin protein ligase 1 targets the full-length ErbB4 for ubiquitin-mediated degradation in breast cancer.
Oncogene28(33)2948-58(2009 Aug)
Li Y,Zhou Z,Alimandi M,Chen C

The E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradation.
Molecular and cellular biology29(3)892-906(2009 Feb)
Feng SM,Muraoka-Cook RS,Hunter D,Sandahl MA,Caskey LS,Miyazawa K,Atfi A,Earp HS 3rd

The Nedd4-like family of E3 ubiquitin ligases and cancer.
Cancer metastasis reviews26(3-4)587-604(2007 Dec)
Chen C,Matesic LE

Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3.
Science (New York, N.Y.)312(5777)1223-7(2006 May)
Jones DC,Wein MN,Oukka M,Hofstaetter JG,Glimcher MJ,Glimcher LH

Identification of new partners of the epithelial sodium channel alpha subunit.
Comptes rendus biologies326(7)615-24(2003 Jul)
Malbert-Colas L,Nicolas G,Galand C,Lecomte MC,Dhermy D

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Wwp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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