Tp53inp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tp53inp1
Entrez Gene ID	297822
Full Name	tumor protein p53 inducible nuclear protein 1
Synonyms	Stinp,Trp53inp1
General protein information	Preferred Names tumor protein p53 inducible nuclear protein 1 Names tumor protein p53-inducible nuclear protein 1 TEAP p53-dependent damage-inducible nuclear protein 1 p53DINP1 stress-induced protein thymus-expressed acidic protein transformation related protein 53 inducible nuclear protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q13
Summary	displays increased expression in response to stress [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017593225.1	XP_017448714.1	tumor protein p53-inducible nuclear protein 1 isoform X1
XM_006237868.2	XP_006237930.1	tumor protein p53-inducible nuclear protein 1 isoform X2
XM_008763529.2	XP_008761751.1	tumor protein p53-inducible nuclear protein 1 isoform X3
XM_017593226.1	XP_017448715.1	tumor protein p53-inducible nuclear protein 1 isoform X3
NM_181084.2	NP_851598.1	tumor protein p53-inducible nuclear protein 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	TP53INP1	NP_001192352.1
Danio rerio (zebrafish)	tp53inp1	NP_001073505.1
Pan troglodytes (chimpanzee)	TP53INP1	XP_001144789.1
Canis lupus familiaris (dog)	TP53INP1	XP_854503.1
Gallus gallus (chicken)	TP53INP1	NP_001026117.1
Mus musculus (house mouse)	Trp53inp1	NP_068697.1
Xenopus tropicalis (tropical clawed frog)	tp53inp1	XP_004915174.1
Homo sapiens (human)	TP53INP1	NP_150601.1
	TP53INP1	XP_001090592.1
Rattus norvegicus (Norway rat)	Tp53inp1	NP_851598.1

Gene Ontology
Bibliography

Related articles in PubMed

MiR-155 Knockout in Fibroblasts Improves Cardiac Remodeling by Targeting Tumor Protein p53-Inducible Nuclear Protein 1.
He W, Huang H, Xie Q, Wang Z, Fan Y, Kong B, Huang D, Xiao Y
Journal of cardiovascular pharmacology and therapeutics21(4)423-35(2016 Jul)

Up-regulation of miRNA-221 inhibits hypoxia/reoxygenation-induced autophagy through the DDIT4/mTORC1 and Tp53inp1/p62 pathways.
Chen Q, Zhou Y, Richards AM, Wang P
Biochemical and biophysical research communications474(1)168-174(2016 05)

TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death.
Seillier M, Peuget S, Gayet O, Gauthier C, N'Guessan P, Monte M, Carrier A, Iovanna JL, Dusetti NJ
Cell death and differentiation19(9)1525-35(2012 Sep)

DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription.
Sancho A, Duran J, Garc?a-Espa?a A, Mauvezin C, Alemu EA, Lamark T, Macias MJ, DeSalle R, Royo M, Sala D, Chicote JU, Palac?n M, Johansen T, Zorzano A
PloS one7(3)e34034(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In conclusion, miRNA-221 exerts cytoprotective effects in hypoxia-reoxygenation injury in association with alterations in autophagic cell injury. Mir-221 may constitute is a novel therapeutic target in the treatment of cardiac I/R injury.
Title: Up-regulation of miRNA-221 inhibits hypoxia/reoxygenation-induced autophagy through the DDIT4/mTORC1 and Tp53inp1/p62 pathways.

Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-Tp53INP1-dependent pathway.
Title: Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway.

The following Tp53inp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tp53inp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa04163	NM_181084.2 Latest version!	Rattus norvegicus tumor protein p53 inducible nuclear protein 1 (Tp53inp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa28037	XM_006237868.2 Latest version!	Rattus norvegicus tumor protein p53 inducible nuclear protein 1 (Tp53inp1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa28038	XM_017593226.1 Latest version!	Rattus norvegicus tumor protein p53 inducible nuclear protein 1 (Tp53inp1), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa28038	XM_008763529.2 Latest version!	Rattus norvegicus tumor protein p53 inducible nuclear protein 1 (Tp53inp1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa45477	XM_017593225.1 Latest version!	Rattus norvegicus tumor protein p53 inducible nuclear protein 1 (Tp53inp1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tp53inp1 ( NM_181084.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_851598.1 Rattus norvegicus tumor protein p53 inducible nuclear protein 1 (Tp53inp1), mRNA.

Price & Availability↑

CloneID	ORa04163
Clone ID Related Accession (Same CDS sequence)	NM_181084.2
Accession Version	NM_181084.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-15
Organism	Rattus norvegicus(Norway rat)
Product	tumor protein p53-inducible nuclear protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB107917.1. On Jun 3, 2003 this sequence version replaced NM_181084.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB107917.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTTTCAGA GACTGAATAA AATGTTTGTA GGTGAAGTCA CTACTTCTTC CAGCCACGAG 
CCAGAATTTA GTGAGAAAGA AGATGATGAG TGGATTCTTG TTGACTTCAT AGATACCTGC 
ACTGGTTTCT CAGCAGAAGA AGAGGAGGAA GATGAGGACA TTGGTGAAGA GTCCTCAGCA 
GAGCACACTT CTGTCTTCTC CTGTTTACCT ACATCTTTGG AGTGCTTGGC TGACACCAGC 
GATTCCTGCT TCCTTCAGTT TGAGTCCTGT CCAATGGAGG AGAGCTGGTT CATCACTCCT 
CCCCCATGTT TTACAGCAGG GGGATTAACC ACTATCAAAG TGGAAACAAG TCCTATGGAA 
AACCTTCTCA TTGAACATCC CAGCATGTCT GTCTATGCTG TGCACAACTC CTGTCCTGGT 
CTCAGTGAAG CTAGCTGTGG GAACGATGAC TATAACTCAA GTGGTCCCAG AATGGAAGCC 
CAGAGTGAAC TGGGGACGCA CATTCACTGC TGTGTTGCAG CGCTTGCTGC TCAGGCAACC 
TTTTTGGAAC AACCCAAGAG TTTTCGCCCT TCCCAGTGGA TAAAAGGACA CAGTGAAAGA 
CAGTCTCTGA ACAGAAATGG CCTCCGTCGC CAGAACCTTA CCAGGGATTG CCACACTCGA 
CAAATGAAGC ACAGGTGCTG GGCGGTTCAC CAGCCCTGCC CACGCCAGTA CAATTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_851598.1
CDS	120..839
Translation	MFQRLNKMFVGEVTTSSSHEPEFSEKEDDEWILVDFIDTCTGFSAEEEEEDEDIGEESSAEHTSVFSCLPTSLECLADTSDSCFLQFESCPMEESWFITPPPCFTAGGLTTIKVETSPMENLLIEHPSMSVYAVHNSCPGLSEASCGNDDYNSSGPRMEAQSELGTHIHCCVAALAAQATFLEQPKSFRPSQWIKGHSERQSLNRNGLRRQNLTRDCHTRQMKHRCWAVHQPCPRQYNY

Target ORF information:

RefSeq Version	NM_181084.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus tumor protein p53 inducible nuclear protein 1 (Tp53inp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181084.2

ORF Insert Sequence:

ATGTTTCAGA GACTGAATAA AATGTTTGTA GGTGAAGTCA CTACTTCTTC CAGCCACGAG 
CCAGAATTTA GTGAGAAAGA AGATGATGAG TGGATTCTTG TTGACTTCAT AGATACCTGC 
ACTGGTTTCT CAGCAGAAGA AGAGGAGGAA GATGAGGACA TTGGTGAAGA GTCCTCAGCA 
GAGCACACTT CTGTCTTCTC CTGTTTACCT ACATCTTTGG AGTGCTTGGC TGACACCAGC 
GATTCCTGCT TCCTTCAGTT TGAGTCCTGT CCAATGGAGG AGAGCTGGTT CATCACTCCT 
CCCCCATGTT TTACAGCAGG GGGATTAACC ACTATCAAAG TGGAAACAAG TCCTATGGAA 
AACCTTCTCA TTGAACATCC CAGCATGTCT GTCTATGCTG TGCACAACTC CTGTCCTGGT 
CTCAGTGAAG CTAGCTGTGG GAACGATGAC TATAACTCAA GTGGTCCCAG AATGGAAGCC 
CAGAGTGAAC TGGGGACGCA CATTCACTGC TGTGTTGCAG CGCTTGCTGC TCAGGCAACC 
TTTTTGGAAC AACCCAAGAG TTTTCGCCCT TCCCAGTGGA TAAAAGGACA CAGTGAAAGA 
CAGTCTCTGA ACAGAAATGG CCTCCGTCGC CAGAACCTTA CCAGGGATTG CCACACTCGA 
CAAATGAAGC ACAGGTGCTG GGCGGTTCAC CAGCCCTGCC CACGCCAGTA CAATTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tp53inp1 ( XM_006237868.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006237930.1 Rattus norvegicus tumor protein p53 inducible nuclear protein 1 (Tp53inp1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa28037
Clone ID Related Accession (Same CDS sequence)	XM_006237868.2
Accession Version	XM_006237868.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	tumor protein p53-inducible nuclear protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006237868.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTTCAGA GACTGAATAA AATGTTTGTA GGTGAAGTCA CTACTTCTTC CAGCCACGAG 
CCAGAATTTA GTGAGAAAGA AGATGATGAG TGGATTCTTG TTGACTTCAT AGATACCTGC 
ACTGGTTTCT CAGCAGAAGA AGAGGAGGAA GATGAAGACA TTGGTGAAGA GTCCTCAGCA 
GAGCACACTT CTGTCTTCTC CTGTTTACCT ACATCTTTGG AGTGCTTGGC TGACACCAGC 
GATTCCTGCT TCCTTCAGTT TGAGTCCTGT CCAATGGAGG AGAGCTGGTT CATCACTCCT 
CCCCCATGTT TTACAGCAGG GGGATTAACC ACTATCAAAG TGGAAACAAG TCCTATGGAA 
AACCTTCTCA TTGAACATCC CAGCATGTCT GTCTATGCTG TGCACAACTC CTGTCCTGGT 
CTCAGTGAAG CTAGCTGTGG GAACGATGAC TATAACTCAA GTGGTCCCAG AATGGAAGCC 
CAGAGTGAAC TGGGGACGCA CATTCACTGC TGTGTTGCAG CGCTTGCTGC TCAGGCAACC 
TTTTTGGAAC AACCCAAGAG TTTTCGCCCT TCCCAGTGGA TAAAAGGACA CAGTGAAAGA 
CAGTCTCTGA ACAGAAATGG CCTCCGTCGC CAGAACCTTA CCAGGGATTA CCACACTCGA 
CAAATGAAGC ACAGTGGCTG GGTGGTTCAC CAGCCCTGCC CACGCCAGTA CAATTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006237930.1
CDS	251..970
Translation	MFQRLNKMFVGEVTTSSSHEPEFSEKEDDEWILVDFIDTCTGFSAEEEEEDEDIGEESSAEHTSVFSCLPTSLECLADTSDSCFLQFESCPMEESWFITPPPCFTAGGLTTIKVETSPMENLLIEHPSMSVYAVHNSCPGLSEASCGNDDYNSSGPRMEAQSELGTHIHCCVAALAAQATFLEQPKSFRPSQWIKGHSERQSLNRNGLRRQNLTRDYHTRQMKHSGWVVHQPCPRQYNY

Target ORF information:

RefSeq Version	XM_006237868.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus tumor protein p53 inducible nuclear protein 1 (Tp53inp1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006237868.2

ORF Insert Sequence:

ATGTTTCAGA GACTGAATAA AATGTTTGTA GGTGAAGTCA CTACTTCTTC CAGCCACGAG 
CCAGAATTTA GTGAGAAAGA AGATGATGAG TGGATTCTTG TTGACTTCAT AGATACCTGC 
ACTGGTTTCT CAGCAGAAGA AGAGGAGGAA GATGAAGACA TTGGTGAAGA GTCCTCAGCA 
GAGCACACTT CTGTCTTCTC CTGTTTACCT ACATCTTTGG AGTGCTTGGC TGACACCAGC 
GATTCCTGCT TCCTTCAGTT TGAGTCCTGT CCAATGGAGG AGAGCTGGTT CATCACTCCT 
CCCCCATGTT TTACAGCAGG GGGATTAACC ACTATCAAAG TGGAAACAAG TCCTATGGAA 
AACCTTCTCA TTGAACATCC CAGCATGTCT GTCTATGCTG TGCACAACTC CTGTCCTGGT 
CTCAGTGAAG CTAGCTGTGG GAACGATGAC TATAACTCAA GTGGTCCCAG AATGGAAGCC 
CAGAGTGAAC TGGGGACGCA CATTCACTGC TGTGTTGCAG CGCTTGCTGC TCAGGCAACC 
TTTTTGGAAC AACCCAAGAG TTTTCGCCCT TCCCAGTGGA TAAAAGGACA CAGTGAAAGA 
CAGTCTCTGA ACAGAAATGG CCTCCGTCGC CAGAACCTTA CCAGGGATTA CCACACTCGA 
CAAATGAAGC ACAGTGGCTG GGTGGTTCAC CAGCCCTGCC CACGCCAGTA CAATTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tp53inp1 ( XM_008763529.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008761751.1 Rattus norvegicus tumor protein p53 inducible nuclear protein 1 (Tp53inp1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa28038
Clone ID Related Accession (Same CDS sequence)	XM_008763529.2 , XM_017593226.1
Accession Version	XM_008763529.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 492bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	tumor protein p53-inducible nuclear protein 1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008763529.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTTCAGA GACTGAATAA AATGTTTGTA GGTGAAGTCA CTACTTCTTC CAGCCACGAG 
CCAGAATTTA GTGAGAAAGA AGATGATGAG TGGATTCTTG TTGACTTCAT AGATACCTGC 
ACTGGTTTCT CAGCAGAAGA AGAGGAGGAA GATGAAGACA TTGGTGAAGA GTCCTCAGCA 
GAGCACACTT CTGTCTTCTC CTGTTTACCT ACATCTTTGG AGTGCTTGGC TGACACCAGC 
GATTCCTGCT TCCTTCAGTT TGAGTCCTGT CCAATGGAGG AGAGCTGGTT CATCACTCCT 
CCCCCATGTT TTACAGCAGG GGGATTAACC ACTATCAAAG TGGAAACAAG TCCTATGGAA 
AACCTTCTCA TTGAACATCC CAGCATGTCT GTCTATGCTG TGCACAACTC CTGTCCTGGT 
CTCAGTGAAG CTAGCTGTGG GAACGATGAC TATAACTCAA GTGGTCCCAG GGCCAGAAAA 
AGCTGCTTAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008761751.1
CDS	239..730
Translation	MFQRLNKMFVGEVTTSSSHEPEFSEKEDDEWILVDFIDTCTGFSAEEEEEDEDIGEESSAEHTSVFSCLPTSLECLADTSDSCFLQFESCPMEESWFITPPPCFTAGGLTTIKVETSPMENLLIEHPSMSVYAVHNSCPGLSEASCGNDDYNSSGPRARKSCL

Target ORF information:

RefSeq Version	XM_008763529.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus tumor protein p53 inducible nuclear protein 1 (Tp53inp1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008763529.2

ORF Insert Sequence:

ATGTTTCAGA GACTGAATAA AATGTTTGTA GGTGAAGTCA CTACTTCTTC CAGCCACGAG 
CCAGAATTTA GTGAGAAAGA AGATGATGAG TGGATTCTTG TTGACTTCAT AGATACCTGC 
ACTGGTTTCT CAGCAGAAGA AGAGGAGGAA GATGAAGACA TTGGTGAAGA GTCCTCAGCA 
GAGCACACTT CTGTCTTCTC CTGTTTACCT ACATCTTTGG AGTGCTTGGC TGACACCAGC 
GATTCCTGCT TCCTTCAGTT TGAGTCCTGT CCAATGGAGG AGAGCTGGTT CATCACTCCT 
CCCCCATGTT TTACAGCAGG GGGATTAACC ACTATCAAAG TGGAAACAAG TCCTATGGAA 
AACCTTCTCA TTGAACATCC CAGCATGTCT GTCTATGCTG TGCACAACTC CTGTCCTGGT 
CTCAGTGAAG CTAGCTGTGG GAACGATGAC TATAACTCAA GTGGTCCCAG GGCCAGAAAA 
AGCTGCTTAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tp53inp1 ( XM_017593226.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017448715.1 Rattus norvegicus tumor protein p53 inducible nuclear protein 1 (Tp53inp1), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa28038
Clone ID Related Accession (Same CDS sequence)	XM_008763529.2 , XM_017593226.1
Accession Version	XM_017593226.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 492bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	tumor protein p53-inducible nuclear protein 1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTTCAGA GACTGAATAA AATGTTTGTA GGTGAAGTCA CTACTTCTTC CAGCCACGAG 
CCAGAATTTA GTGAGAAAGA AGATGATGAG TGGATTCTTG TTGACTTCAT AGATACCTGC 
ACTGGTTTCT CAGCAGAAGA AGAGGAGGAA GATGAAGACA TTGGTGAAGA GTCCTCAGCA 
GAGCACACTT CTGTCTTCTC CTGTTTACCT ACATCTTTGG AGTGCTTGGC TGACACCAGC 
GATTCCTGCT TCCTTCAGTT TGAGTCCTGT CCAATGGAGG AGAGCTGGTT CATCACTCCT 
CCCCCATGTT TTACAGCAGG GGGATTAACC ACTATCAAAG TGGAAACAAG TCCTATGGAA 
AACCTTCTCA TTGAACATCC CAGCATGTCT GTCTATGCTG TGCACAACTC CTGTCCTGGT 
CTCAGTGAAG CTAGCTGTGG GAACGATGAC TATAACTCAA GTGGTCCCAG GGCCAGAAAA 
AGCTGCTTAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017448715.1
CDS	239..730
Translation	MFQRLNKMFVGEVTTSSSHEPEFSEKEDDEWILVDFIDTCTGFSAEEEEEDEDIGEESSAEHTSVFSCLPTSLECLADTSDSCFLQFESCPMEESWFITPPPCFTAGGLTTIKVETSPMENLLIEHPSMSVYAVHNSCPGLSEASCGNDDYNSSGPRARKSCL

Target ORF information:

RefSeq Version	XM_017593226.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus tumor protein p53 inducible nuclear protein 1 (Tp53inp1), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017593226.1

ORF Insert Sequence:

ATGTTTCAGA GACTGAATAA AATGTTTGTA GGTGAAGTCA CTACTTCTTC CAGCCACGAG 
CCAGAATTTA GTGAGAAAGA AGATGATGAG TGGATTCTTG TTGACTTCAT AGATACCTGC 
ACTGGTTTCT CAGCAGAAGA AGAGGAGGAA GATGAAGACA TTGGTGAAGA GTCCTCAGCA 
GAGCACACTT CTGTCTTCTC CTGTTTACCT ACATCTTTGG AGTGCTTGGC TGACACCAGC 
GATTCCTGCT TCCTTCAGTT TGAGTCCTGT CCAATGGAGG AGAGCTGGTT CATCACTCCT 
CCCCCATGTT TTACAGCAGG GGGATTAACC ACTATCAAAG TGGAAACAAG TCCTATGGAA 
AACCTTCTCA TTGAACATCC CAGCATGTCT GTCTATGCTG TGCACAACTC CTGTCCTGGT 
CTCAGTGAAG CTAGCTGTGG GAACGATGAC TATAACTCAA GTGGTCCCAG GGCCAGAAAA 
AGCTGCTTAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tp53inp1 ( XM_017593225.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017448714.1 Rattus norvegicus tumor protein p53 inducible nuclear protein 1 (Tp53inp1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa45477
Clone ID Related Accession (Same CDS sequence)	XM_017593225.1
Accession Version	XM_017593225.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 750bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	tumor protein p53-inducible nuclear protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTTCAGA GACTGAATAA AATGTTTGTA GGTGAAGTCA CTACTTCTTC CAGCCACGAG 
CCAGAATTTA GTGAGAAAGA AGATGATGAG TGGATTCTTG TTGACTTCAT AGATACCTGC 
ACTGGTTTCT CAGCAGAAGA AGAGGAGGAA GATGAAGACA TTGGTGAAGA GTCCTCAGCA 
GAGCACACTT CTGTCTTCTC CTGTTTACCT ACATCTTTGG AGTGCTTGGC TGACACCAGC 
GATTCCTGCT TCCTTCAGTT TGAGTCCTGT CCAATGGAGG AGAGCTGGTT CATCACTCCT 
CCCCCATGTT TTACAGCAGG GGGATTAACC ACTATCAAAG TGGAAACAAG TCCTATGGAA 
AACCTTCTCA TTGAACATCC CAGCATGTCT GTCTATGCTG TGCACAACTC CTGTCCTGGT 
CTCAGTGAAG CTAGCTGTGG GAACGATGAC TATAACTCAA GTGGTCCCAG GTATGCTGCA 
AGCACTTCAC TCTGCCTAAG TGATCTGCTA AGCAAAAGTT TCATTTCTAC ACAGAACACA 
GCTAAGGCTT TAGAAGACAT GAAACTAAGT GTGCTAGAAA TGTACTTAAG TAACTTGGGC 
TATAAATGCA ACATTCAGGT CAAGATTGCG TTTTATAAGG TTATTAATTG TAGCATGGCT 
CAGTTGTATA ATAGCCATTT CGTTTATAAA ATCATGCTAC TGATGGGAAA TAAAAAGACT 
AGTATTTCTG ATAAGTATAT TAGAATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017448714.1
CDS	239..988
Translation	MFQRLNKMFVGEVTTSSSHEPEFSEKEDDEWILVDFIDTCTGFSAEEEEEDEDIGEESSAEHTSVFSCLPTSLECLADTSDSCFLQFESCPMEESWFITPPPCFTAGGLTTIKVETSPMENLLIEHPSMSVYAVHNSCPGLSEASCGNDDYNSSGPRYAASTSLCLSDLLSKSFISTQNTAKALEDMKLSVLEMYLSNLGYKCNIQVKIAFYKVINCSMAQLYNSHFVYKIMLLMGNKKTSISDKYIRM

Target ORF information:

RefSeq Version	XM_017593225.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus tumor protein p53 inducible nuclear protein 1 (Tp53inp1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017593225.1

ORF Insert Sequence:

ATGTTTCAGA GACTGAATAA AATGTTTGTA GGTGAAGTCA CTACTTCTTC CAGCCACGAG 
CCAGAATTTA GTGAGAAAGA AGATGATGAG TGGATTCTTG TTGACTTCAT AGATACCTGC 
ACTGGTTTCT CAGCAGAAGA AGAGGAGGAA GATGAAGACA TTGGTGAAGA GTCCTCAGCA 
GAGCACACTT CTGTCTTCTC CTGTTTACCT ACATCTTTGG AGTGCTTGGC TGACACCAGC 
GATTCCTGCT TCCTTCAGTT TGAGTCCTGT CCAATGGAGG AGAGCTGGTT CATCACTCCT 
CCCCCATGTT TTACAGCAGG GGGATTAACC ACTATCAAAG TGGAAACAAG TCCTATGGAA 
AACCTTCTCA TTGAACATCC CAGCATGTCT GTCTATGCTG TGCACAACTC CTGTCCTGGT 
CTCAGTGAAG CTAGCTGTGG GAACGATGAC TATAACTCAA GTGGTCCCAG GTATGCTGCA 
AGCACTTCAC TCTGCCTAAG TGATCTGCTA AGCAAAAGTT TCATTTCTAC ACAGAACACA 
GCTAAGGCTT TAGAAGACAT GAAACTAAGT GTGCTAGAAA TGTACTTAAG TAACTTGGGC 
TATAAATGCA ACATTCAGGT CAAGATTGCG TTTTATAAGG TTATTAATTG TAGCATGGCT 
CAGTTGTATA ATAGCCATTT CGTTTATAAA ATCATGCTAC TGATGGGAAA TAAAAAGACT 
AGTATTTCTG ATAAGTATAT TAGAATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MiR-155 Knockout in Fibroblasts Improves Cardiac Remodeling by Targeting Tumor Protein p53-Inducible Nuclear Protein 1.
Journal of cardiovascular pharmacology and therapeutics21(4)423-35(2016 Jul)
He W,Huang H,Xie Q,Wang Z,Fan Y,Kong B,Huang D,Xiao Y

Up-regulation of miRNA-221 inhibits hypoxia/reoxygenation-induced autophagy through the DDIT4/mTORC1 and Tp53inp1/p62 pathways.
Biochemical and biophysical research communications474(1)168-174(2016 05)
Chen Q,Zhou Y,Richards AM,Wang P

TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death.
Cell death and differentiation19(9)1525-35(2012 Sep)
Seillier M,Peuget S,Gayet O,Gauthier C,N'Guessan P,Monte M,Carrier A,Iovanna JL,Dusetti NJ

DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription.
PloS one7(3)e34034(2012)
Sancho A,Duran J,Garc?a-Espa?a A,Mauvezin C,Alemu EA,Lamark T,Macias MJ,DeSalle R,Royo M,Sala D,Chicote JU,Palac?n M,Johansen T,Zorzano A

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Tp53inp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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