Terf1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Terf1
Entrez Gene ID	297758
Full Name	telomeric repeat binding factor 1
General protein information	Preferred Names telomeric repeat binding factor 1 Names telomeric repeat-binding factor 1 telomeric repeat binding factor (NIMA-interacting) 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001012464.1	NP_001012482.1	telomeric repeat-binding factor 1
XM_006237729.3	XP_006237791.1	telomeric repeat-binding factor 1 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	TERF1	XP_003433712.1
Bos taurus (cattle)	TERF1	NP_001070333.1
Homo sapiens (human)	TERF1	NP_059523.2
Pan troglodytes (chimpanzee)	TERF1	XP_001164723.1
	TERF1	XP_001083645.1
Xenopus tropicalis (tropical clawed frog)	terf1	NP_001137394.1
Rattus norvegicus (Norway rat)	Terf1	NP_001012482.1
Mus musculus (house mouse)	Terf1	NP_033378.1
Gallus gallus (chicken)	TERF1	NP_989711.2
Danio rerio (zebrafish)	terf1	XP_695329.5

Gene Ontology
Bibliography

Related articles in PubMed

ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres.
Tong AS, Stern JL, Sfeir A, Kartawinata M, de Lange T, Zhu XD, Bryan TM
Cell reports13(8)1633-46(2015 Nov)

Single-strand DNA-binding protein SSB1 facilitates TERT recruitment to telomeres and maintains telomere G-overhangs.
Pandita RK, Chow TT, Udayakumar D, Bain AL, Cubeddu L, Hunt CR, Shi W, Horikoshi N, Zhao Y, Wright WE, Khanna KK, Shay JW, Pandita TK
Cancer research75(5)858-69(2015 Mar)

Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes.
Ishiguro K, Kim J, Shibuya H, Hern?ndez-Hern?ndez A, Suzuki A, Fukagawa T, Shioi G, Kiyonari H, Li XC, Schimenti J, H??g C, Watanabe Y
Genes & development28(6)594-607(2014 Mar)

PinX1, a telomere repeat-binding factor 1 (TRF1)-interacting protein, maintains telomere integrity by modulating TRF1 homeostasis, the process in which human telomerase reverse Transcriptase (hTERT) plays dual roles.
Yoo JE, Park YN, Oh BK
The Journal of biological chemistry289(10)6886-98(2014 Mar)

A quantitative telomeric chromatin isolation protocol identifies different telomeric states.
Grolimund L, Aeby E, Hamelin R, Armand F, Chiappe D, Moniatte M, Lingner J
Nature communications42848(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Doxorubicin induces senescence or apoptosis in rat neonatal cardiomyocytes by regulating the expression levels of the telomere binding factors 1 and 2.
Title: Doxorubicin induces senescence or apoptosis in rat neonatal cardiomyocytes by regulating the expression levels of the telomere binding factors 1 and 2.

The following Terf1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Terf1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02928	NM_001012464.1 Latest version!	Rattus norvegicus telomeric repeat binding factor 1 (Terf1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
ORa27959	XM_006237729.3 Latest version!	Rattus norvegicus telomeric repeat binding factor 1 (Terf1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Terf1 ( NM_001012464.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001012482.1 Rattus norvegicus telomeric repeat binding factor 1 (Terf1), mRNA.

Price & Availability↑

CloneID	ORa02928
Clone ID Related Accession (Same CDS sequence)	NM_001012464.1
Accession Version	NM_001012464.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1266bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Rattus norvegicus(Norway rat)
Product	telomeric repeat-binding factor 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC089888.1. On Apr 20, 2005 this sequence version replaced XM_238387.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC089888.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGGGA CTGTCACCTC AGCAGCTCCG GGCGCGCGGA GCAATGCGGG CGGGACAAGC 
GCGGATTCTC CAGAGAAGGA GGCGGCGAGA GACGACGCAG AGTTGTTCGA CTGCCGGGTG 
CAGCTGGGGC CCCCGAGAGA GGAGGAGAAC GCGGAGCTTG TGGCCGAGGC GGAGGCCGTG 
GCTGCGGGCT GGATGCTCGA CTTCCTCTGC CTGTCTCTGT GCCGAGCCTT TCGCGACGGC 
CGCTGCGAGG ACTTTCGCCA GACTCGTGAC AGCGCCGAGG CTATTATTCA TGGACTACCC 
AGTCTTACAG CTTACCAGTT GAAAACTGTA TATATATGTC AGTTTTTGAC AAGAGTTGCA 
GCAGGAAAGT CTCTTGATGC ACAGTTTGAA GTTGATGAGC GGATTACACC CTTGGAATCA 
GCCCTGATGA TTTGGGACTC AATTGAAAAA GAACATGACA AACTTCATGA AGAAATACAG 
AATTTAATTA AAATTCAGGC TGTAGCTGTG TGTATGGAAA TGGGCAGCTT TAAGGAAGCA 
GAAGAAGTGT TTGAAAGAAT ATTTGGTGAC CCAGAATTTT ACACGCCTTT AGAAAGAAAA 
TTACTTAAGA TAATCTCTCA AAAAGACGTC TTCCACGTCC TTTTTCAACG CTTCAGTTAT 
AACCTCATGA TGGAGAAAAT TCAGAGTTAT GTGGAGTGTG TGTTAAATGA GAAATCATCA 
ACTTTCCTAA TGAAGGCAGC AACAAAAGTA GTGGAAAATG AAAAAGCAAG GACAGTAGCT 
TCGGAGGATA AAGCAAAGGC CACCAACACT GGAACAGAAA CGGAAGTTAA CTCGAATAAA 
GGAGAAAGTG TTAATGGCCA ACAGTCTGTA GAAACTGAAT CCTTGGTGGA TACAGGATCC 
TCAGTAAGGT CTCACAAGAA TGCCTTATCT CCGTTGAAAA GCAGACGTCT TCAGCCAGAT 
TTCAATAGGA ATGAAGCAAG AACAGGAACT CTTCAGTGTG AAATAGCAAC AAAACGAAAC 
AGAAGAACCA GTGGAGGGAA TAGATTACGT ATTTCAAAGA ATCAGCCGGA CACTAATGAA 
AAACATGGGC GCAGGAAAAA ACAGACATGG CTTTGGGAAG AAGACAGAAG TTTGAAGTGT 
GGTGTAAGGA AATATGGAGA GGGAAATTGG GCTAAAATAC TATCCCATTA TAAGTTCAAC 
AACCGAACAA GTGTCATGTT AAAGGATCGG TGGAGAACGA TGAGGAGGCT AAGGCTCATT 
AGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012482.1
CDS	1..1266
Translation	MAGTVTSAAPGARSNAGGTSADSPEKEAARDDAELFDCRVQLGPPREEENAELVAEAEAVAAGWMLDFLCLSLCRAFRDGRCEDFRQTRDSAEAIIHGLPSLTAYQLKTVYICQFLTRVAAGKSLDAQFEVDERITPLESALMIWDSIEKEHDKLHEEIQNLIKIQAVAVCMEMGSFKEAEEVFERIFGDPEFYTPLERKLLKIISQKDVFHVLFQRFSYNLMMEKIQSYVECVLNEKSSTFLMKAATKVVENEKARTVASEDKAKATNTGTETEVNSNKGESVNGQQSVETESLVDTGSSVRSHKNALSPLKSRRLQPDFNRNEARTGTLQCEIATKRNRRTSGGNRLRISKNQPDTNEKHGRRKKQTWLWEEDRSLKCGVRKYGEGNWAKILSHYKFNNRTSVMLKDRWRTMRRLRLIS

Target ORF information:

RefSeq Version	NM_001012464.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus telomeric repeat binding factor 1 (Terf1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012464.1

ORF Insert Sequence:

ATGGCGGGGA CTGTCACCTC AGCAGCTCCG GGCGCGCGGA GCAATGCGGG CGGGACAAGC 
GCGGATTCTC CAGAGAAGGA GGCGGCGAGA GACGACGCAG AGTTGTTCGA CTGCCGGGTG 
CAGCTGGGGC CCCCGAGAGA GGAGGAGAAC GCGGAGCTTG TGGCCGAGGC GGAGGCCGTG 
GCTGCGGGCT GGATGCTCGA CTTCCTCTGC CTGTCTCTGT GCCGAGCCTT TCGCGACGGC 
CGCTGCGAGG ACTTTCGCCA GACTCGTGAC AGCGCCGAGG CTATTATTCA TGGACTACCC 
AGTCTTACAG CTTACCAGTT GAAAACTGTA TATATATGTC AGTTTTTGAC AAGAGTTGCA 
GCAGGAAAGT CTCTTGATGC ACAGTTTGAA GTTGATGAGC GGATTACACC CTTGGAATCA 
GCCCTGATGA TTTGGGACTC AATTGAAAAA GAACATGACA AACTTCATGA AGAAATACAG 
AATTTAATTA AAATTCAGGC TGTAGCTGTG TGTATGGAAA TGGGCAGCTT TAAGGAAGCA 
GAAGAAGTGT TTGAAAGAAT ATTTGGTGAC CCAGAATTTT ACACGCCTTT AGAAAGAAAA 
TTACTTAAGA TAATCTCTCA AAAAGACGTC TTCCACGTCC TTTTTCAACG CTTCAGTTAT 
AACCTCATGA TGGAGAAAAT TCAGAGTTAT GTGGAGTGTG TGTTAAATGA GAAATCATCA 
ACTTTCCTAA TGAAGGCAGC AACAAAAGTA GTGGAAAATG AAAAAGCAAG GACAGTAGCT 
TCGGAGGATA AAGCAAAGGC CACCAACACT GGAACAGAAA CGGAAGTTAA CTCGAATAAA 
GGAGAAAGTG TTAATGGCCA ACAGTCTGTA GAAACTGAAT CCTTGGTGGA TACAGGATCC 
TCAGTAAGGT CTCACAAGAA TGCCTTATCT CCGTTGAAAA GCAGACGTCT TCAGCCAGAT 
TTCAATAGGA ATGAAGCAAG AACAGGAACT CTTCAGTGTG AAATAGCAAC AAAACGAAAC 
AGAAGAACCA GTGGAGGGAA TAGATTACGT ATTTCAAAGA ATCAGCCGGA CACTAATGAA 
AAACATGGGC GCAGGAAAAA ACAGACATGG CTTTGGGAAG AAGACAGAAG TTTGAAGTGT 
GGTGTAAGGA AATATGGAGA GGGAAATTGG GCTAAAATAC TATCCCATTA TAAGTTCAAC 
AACCGAACAA GTGTCATGTT AAAGGATCGG TGGAGAACGA TGAGGAGGCT AAGGCTCATT 
AGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Terf1 ( XM_006237729.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006237791.1 Rattus norvegicus telomeric repeat binding factor 1 (Terf1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa27959
Clone ID Related Accession (Same CDS sequence)	XM_006237729.3
Accession Version	XM_006237729.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1179bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	telomeric repeat-binding factor 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006237729.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGGGA CTGTCACCTC AGCAGCTCCG GGCGCGCGGA GCAATGCGGG CGGGACAAGC 
GCGGATTCTC CAGAGAAGGA GGCGGCGAGA GACGACGCAG AGTTGTTCGA CTGCCGGGTG 
CAGCTGGGGC CCCCGAGAGA GGAGGAGAAC GCGGAGCTTG TGGCCGAGGC GGAGGCCGTG 
GCTGCGGGCT GGATGCTCGA CTTCCTCTGC CTGTCTCTGT GCCGAGCCTT TCGCGACGGC 
CGCTGCGAGG ACTTTCGCCA GACTCGTGAC AGCGCCGAGG CTATTATTCA TGGACTACCC 
AGTCTTACAG CTTACCAGTT GAAAACTGTA TATATATGTC AGTTTTTGAC AAGAGTTGCA 
GCAGGAAAGT CTCTTGATGC ACAGTTTGAA GTTGATGAGC GGATTACACC CTTGGAATCA 
GCCCTGATGA TTTGGGACTC AATTGAAAAA GAACATGACA AACTTCATGA AGAAATACAG 
AATTTAATTA AAATTCAGCC TTTAGAAAGA AAATTACTTA AGATAATCTC TCAAAAAGAC 
GTCTTCCACG TCCTTTTTCA ACGCTTCAGT TATAACCTCA TGATGGAGAA AATTCAGAGT 
TATGTGGAGT GTGTGTTAAA TGAGAAATCA TCAACTTTCC TAATGAAGGC AGCAACAAAA 
GTAGTGGAAA ATGAAAAAGC AAGGACAGTA GCTTCGGAGG ATAAAGCAAA GGCCACCAAC 
ACTGGAACAG AAACGGAAGT TAACTCGAAT AAAGGAGAAA GTGTTAATGG CCAACAGTCT 
GTAGAAACTG AATCCTTGGT GGATACAGGA TCCTCAGTAA GGTCTCACAA GAATGCCTTA 
TCTCCGTTGA AAAGCAGACG TCTTCAGCCA GATTTCAATA GGAATGAAGC AAGAACAGGA 
ACTCTTCAGT GTGAAATAGC AACAAAACGA AACAGAAGAA CCAGTGGAGG GAATAGATTA 
CGTATTTCAA AGAATCAGCC GGACACTAAT GAAAAACATG GGCGCAGGAA AAAACAGACA 
TGGCTTTGGG AAGAAGACAG AAGTTTGAAG TGTGGTGTAA GGAAATATGG AGAGGGAAAT 
TGGGCTAAAA TACTATCCCA TTATAAGTTC AACAACCGAA CAAGTGTCAT GTTAAAGGAT 
CGGTGGAGAA CGATGAGGAG GCTAAGGCTC ATTAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006237791.1
CDS	64..1242
Translation	MAGTVTSAAPGARSNAGGTSADSPEKEAARDDAELFDCRVQLGPPREEENAELVAEAEAVAAGWMLDFLCLSLCRAFRDGRCEDFRQTRDSAEAIIHGLPSLTAYQLKTVYICQFLTRVAAGKSLDAQFEVDERITPLESALMIWDSIEKEHDKLHEEIQNLIKIQPLERKLLKIISQKDVFHVLFQRFSYNLMMEKIQSYVECVLNEKSSTFLMKAATKVVENEKARTVASEDKAKATNTGTETEVNSNKGESVNGQQSVETESLVDTGSSVRSHKNALSPLKSRRLQPDFNRNEARTGTLQCEIATKRNRRTSGGNRLRISKNQPDTNEKHGRRKKQTWLWEEDRSLKCGVRKYGEGNWAKILSHYKFNNRTSVMLKDRWRTMRRLRLIS

Target ORF information:

RefSeq Version	XM_006237729.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus telomeric repeat binding factor 1 (Terf1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006237729.3

ORF Insert Sequence:

ATGGCGGGGA CTGTCACCTC AGCAGCTCCG GGCGCGCGGA GCAATGCGGG CGGGACAAGC 
GCGGATTCTC CAGAGAAGGA GGCGGCGAGA GACGACGCAG AGTTGTTCGA CTGCCGGGTG 
CAGCTGGGGC CCCCGAGAGA GGAGGAGAAC GCGGAGCTTG TGGCCGAGGC GGAGGCCGTG 
GCTGCGGGCT GGATGCTCGA CTTCCTCTGC CTGTCTCTGT GCCGAGCCTT TCGCGACGGC 
CGCTGCGAGG ACTTTCGCCA GACTCGTGAC AGCGCCGAGG CTATTATTCA TGGACTACCC 
AGTCTTACAG CTTACCAGTT GAAAACTGTA TATATATGTC AGTTTTTGAC AAGAGTTGCA 
GCAGGAAAGT CTCTTGATGC ACAGTTTGAA GTTGATGAGC GGATTACACC CTTGGAATCA 
GCCCTGATGA TTTGGGACTC AATTGAAAAA GAACATGACA AACTTCATGA AGAAATACAG 
AATTTAATTA AAATTCAGCC TTTAGAAAGA AAATTACTTA AGATAATCTC TCAAAAAGAC 
GTCTTCCACG TCCTTTTTCA ACGCTTCAGT TATAACCTCA TGATGGAGAA AATTCAGAGT 
TATGTGGAGT GTGTGTTAAA TGAGAAATCA TCAACTTTCC TAATGAAGGC AGCAACAAAA 
GTAGTGGAAA ATGAAAAAGC AAGGACAGTA GCTTCGGAGG ATAAAGCAAA GGCCACCAAC 
ACTGGAACAG AAACGGAAGT TAACTCGAAT AAAGGAGAAA GTGTTAATGG CCAACAGTCT 
GTAGAAACTG AATCCTTGGT GGATACAGGA TCCTCAGTAA GGTCTCACAA GAATGCCTTA 
TCTCCGTTGA AAAGCAGACG TCTTCAGCCA GATTTCAATA GGAATGAAGC AAGAACAGGA 
ACTCTTCAGT GTGAAATAGC AACAAAACGA AACAGAAGAA CCAGTGGAGG GAATAGATTA 
CGTATTTCAA AGAATCAGCC GGACACTAAT GAAAAACATG GGCGCAGGAA AAAACAGACA 
TGGCTTTGGG AAGAAGACAG AAGTTTGAAG TGTGGTGTAA GGAAATATGG AGAGGGAAAT 
TGGGCTAAAA TACTATCCCA TTATAAGTTC AACAACCGAA CAAGTGTCAT GTTAAAGGAT 
CGGTGGAGAA CGATGAGGAG GCTAAGGCTC ATTAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres.
Cell reports13(8)1633-46(2015 Nov)
Tong AS,Stern JL,Sfeir A,Kartawinata M,de Lange T,Zhu XD,Bryan TM

Single-strand DNA-binding protein SSB1 facilitates TERT recruitment to telomeres and maintains telomere G-overhangs.
Cancer research75(5)858-69(2015 Mar)
Pandita RK,Chow TT,Udayakumar D,Bain AL,Cubeddu L,Hunt CR,Shi W,Horikoshi N,Zhao Y,Wright WE,Khanna KK,Shay JW,Pandita TK

Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes.
Genes & development28(6)594-607(2014 Mar)
Ishiguro K,Kim J,Shibuya H,Hern?ndez-Hern?ndez A,Suzuki A,Fukagawa T,Shioi G,Kiyonari H,Li XC,Schimenti J,H??g C,Watanabe Y

PinX1, a telomere repeat-binding factor 1 (TRF1)-interacting protein, maintains telomere integrity by modulating TRF1 homeostasis, the process in which human telomerase reverse Transcriptase (hTERT) plays dual roles.
The Journal of biological chemistry289(10)6886-98(2014 Mar)
Yoo JE,Park YN,Oh BK

A quantitative telomeric chromatin isolation protocol identifies different telomeric states.
Nature communications42848(2013)
Grolimund L,Aeby E,Hamelin R,Armand F,Chiappe D,Moniatte M,Lingner J

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Terf1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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