Dusp16 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dusp16
Entrez Gene ID	297682
Full Name	dual specificity phosphatase 16
Synonyms	Mkp-7,Mkp7
General protein information	Preferred Names dual specificity phosphatase 16 Names dual specificity protein phosphatase 16
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q43

mRNA and Protein(s)

mRNA	Protein	Name
XM_008763374.2	XP_008761596.1	dual specificity protein phosphatase 16 isoform X1
NM_001106624.2	NP_001100094.1	dual specificity protein phosphatase 16

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	DUSP16	XP_520751.2
Danio rerio (zebrafish)	dusp16	NP_998405.1
Bos taurus (cattle)	DUSP16	XP_002687822.1
Canis lupus familiaris (dog)	DUSP16	XP_005637191.1
Homo sapiens (human)	DUSP16	NP_085143.1
Mus musculus (house mouse)	Dusp16	NP_569714.2
Gallus gallus (chicken)	DUSP16	XP_428887.3
	DUSP16	XP_001084619.1
Rattus norvegicus (Norway rat)	Dusp16	NP_001100094.1
Xenopus tropicalis (tropical clawed frog)	dusp16	NP_001090711.1

Gene Ontology
Bibliography

Related articles in PubMed

The family-wide structure and function of human dual-specificity protein phosphatases.
Jeong DG, Wei CH, Ku B, Jeon TJ, Chien PN, Kim JK, Park SY, Hwang HS, Ryu SY, Park H, Kim DS, Kim SJ, Ryu SE
Acta crystallographica. Section D, Biological crystallography70(Pt 2)421-35(2014 Feb)

PI3K/Akt-independent negative regulation of JNK signaling by MKP-7 after cerebral ischemia in rat hippocampus.
Zhu J, Shen W, Gao L, Gu H, Shen S, Wang Y, Wu H, Guo J
BMC neuroscience141(2013 Jan)

Mechanisms and functions of p38 MAPK signalling.
Cuadrado A, Nebreda AR
The Biochemical journal429(3)403-17(2010 Aug)

Regulation of MAP kinases by MAP kinase phosphatases.
Kondoh K, Nishida E
Biochimica et biophysica acta1773(8)1227-37(2007 Aug)

MKP-7, a novel mitogen-activated protein kinase phosphatase, functions as a shuttle protein.
Masuda K, Shima H, Watanabe M, Kikuchi K
The Journal of biological chemistry276(42)39002-11(2001 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Dusp16 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dusp16 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01820	NM_001106624.2 Latest version!	Rattus norvegicus dual specificity phosphatase 16 (Dusp16), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa01820	XM_008763374.2 Latest version!	Rattus norvegicus dual specificity phosphatase 16 (Dusp16), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dusp16 ( NM_001106624.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100094.1 Rattus norvegicus dual specificity phosphatase 16 (Dusp16), mRNA.

Price & Availability↑

CloneID	ORa01820
Clone ID Related Accession (Same CDS sequence)	XM_008763374.2 , NM_001106624.2
Accession Version	NM_001106624.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1986bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity protein phosphatase 16
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473964.2. On Mar 3, 2011 this sequence version replaced NM_001106624.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCCCATG AGATGACTGG AACTCAAATT GTTACTGAGA GGTTGGTGGC TCTGTTGGAA 
AGCGGCACCG AGAAAGTGCT GCTAATTGAC AGCCGGCCAT TTGTGGAGTA CAATACGTCC 
CACATTCTGG AAGCCATCAA TATCAACTGC TCCAAACTGA TGAAGCGAAG GCTGCAACAA 
GACAAAGTAT TAATTACAGA ACTCATCCAG CATTCTGCAA AACATAAGGT TGACATTGAC 
TGCAGTCAGA AGGTGGTAGT GTATGATCAG AGTTCCCAGG ATGTTGGTTC TCTGTCGTCA 
GACTGCTTTC TCACTGTGCT TCTGGGTAAG CTGGAGAAGA GCTTCAACTC TGTTCACCTG 
CTTGCAGGTG GGTTTGCTGA GTTCTCTCGT TGTTTCCCTG GCCTCTGTGA AGGAAAATCC 
ACTCTAGTCC CTACCTGCAT ATCTCAGCCT TGCCTACCTG TTGCCAACAC TGGGCCAACT 
CGAATTCTTC CCAATCTCTA TCTCGGCTGC CAGCGAGATG TCCTCAACAA GGAGCTGATG 
CAACAGAACG GGATTGGCTA TGTGCTAAAT GCCAGCAACA CCTGTCCAAA GCCTGACTTC 
ATACCCGAAT CTCACTTCCT GCGAGTGCCT GTGAATGACA GCTTTTGTGA GAAAATCCTG 
CCCTGGTTGG ACAAGTCTGT GGATTTCATT GAGAAAGCAA AAGCCTCCAA CGGCTGTGTG 
CTGATCCACT GCTTGGCTGG GATCTCCCGC TCGGCCACCA TTGCTATTGC CTATATCATG 
AAGAGGATGG ACATGTCTCT GGATGAGGCT TACAGATTTG TGAAAGAAAA AAGACCTACT 
ATATCTCCGA ACTTTAATTT TATGGGCCAA CTCATGGACT ATGAGAAGAC GATTAGTAGC 
CAGACTGGAA TGTCCGGGCC GAAGAGCAAA CTCAAGCTGC TGCACCTGGA CAAAGCCAGT 
GAGCCTGTGC CTGCAGCCTC AGAGGGCGGA CGGAAGAATG CACTGTCTCT CAGCCCACCC 
TGTGCCAACT CTACCTCAGA GGCAGTGGGG CAAAGGCTTG TGCATCCTGC AAGTGTGCCC 
AGCTTACAGC CTTCCCTCTT GGAGGACAGT CCGCTGGTAC AGGCGCTCAG TGGGCTCCAG 
CTGTCCTCAG AGAAGCTGGA AGACAGCAAC AGGCTCAAGC GTTCCTTCTC TCTCGATATC 
AAGTCTGTTT CGTATTCAGC CAGTGTGGCA GCGTCCTTAC ACGGCTTCTC GTCAGAGGAT 
GCTATGGAGT ACTACAAACC TTCCGCCACA CTGGATGGGA CCAGCAAGCT CTGCCAGTTC 
TCCCCCGTTC AGGAGGTATC AGAACAGACT CCAGAGACCA GCCCCGATAA GGAGGAGGCC 
CACATCCCCA GGCAGCCCCA AGCTACCAGA CCTTCAGAGA GCCAGACCAC ACGGCTGCAC 
TCAGTGAGAA CCAGCAGTAC TGGGTCTACC CAGAGGCCCT TCTTCTCGCC ACTGCATCGG 
AGCGGGAGTG TGGAGGACAA CTACCACACC AACTTCCTTT TTGGCCTTTC CACCAGCCAG 
CAGCACCTCA CCAAGTCTGC TGCAGGGCTT GGCCTCAAGG GCTGGCACTC AGACATTCTG 
CCTCCCCAGT CCTCTGCCCC TTCCCTGACC AGCGGTTGGT ATTTTGCTAC AGAGCCTTCA 
CACTTCTACT CTGCTTCAGC CATCTATGGA GGCAACGCCA GTTACTCTGC CTACAGCTGT 
AGCCAGCTGC CCACTTGCAG TGACCAAATC TATTCTGTTC GTAGGCGGCA GAAGCCTAGT 
GACAGAGCTG ACTCACGGCG GAGCTGGCAT GAAGAGAGCC CCTTTGAGAA GCAGTTTAAA 
CGCAGGAGCT GCCAAATGGA ATTTGGAGAG AGCATTATGT CAGAGAACAG GTCGAGGGAA 
GAACTGGGCA AAGTGGGGAG CCAATCTAGC TTTTCAGGAA GCATGGAGGT CATTGAGGTC 
TCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100094.1
CDS	1..1986
Translation	MAHEMTGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVGSLSSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANTGPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLIHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFMGQLMDYEKTISSQTGMSGPKSKLKLLHLDKASEPVPAASEGGRKNALSLSPPCANSTSEAVGQRLVHPASVPSLQPSLLEDSPLVQALSGLQLSSEKLEDSNRLKRSFSLDIKSVSYSASVAASLHGFSSEDAMEYYKPSATLDGTSKLCQFSPVQEVSEQTPETSPDKEEAHIPRQPQATRPSESQTTRLHSVRTSSTGSTQRPFFSPLHRSGSVEDNYHTNFLFGLSTSQQHLTKSAAGLGLKGWHSDILPPQSSAPSLTSGWYFATEPSHFYSASAIYGGNASYSAYSCSQLPTCSDQIYSVRRRQKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSMEVIEVS

Target ORF information:

RefSeq Version	NM_001106624.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity phosphatase 16 (Dusp16), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106624.2

ORF Insert Sequence:

ATGGCCCATG AGATGACTGG AACTCAAATT GTTACTGAGA GGTTGGTGGC TCTGTTGGAA 
AGCGGCACCG AGAAAGTGCT GCTAATTGAC AGCCGGCCAT TTGTGGAGTA CAATACGTCC 
CACATTCTGG AAGCCATCAA TATCAACTGC TCCAAACTGA TGAAGCGAAG GCTGCAACAA 
GACAAAGTAT TAATTACAGA ACTCATCCAG CATTCTGCAA AACATAAGGT TGACATTGAC 
TGCAGTCAGA AGGTGGTAGT GTATGATCAG AGTTCCCAGG ATGTTGGTTC TCTGTCGTCA 
GACTGCTTTC TCACTGTGCT TCTGGGTAAG CTGGAGAAGA GCTTCAACTC TGTTCACCTG 
CTTGCAGGTG GGTTTGCTGA GTTCTCTCGT TGTTTCCCTG GCCTCTGTGA AGGAAAATCC 
ACTCTAGTCC CTACCTGCAT ATCTCAGCCT TGCCTACCTG TTGCCAACAC TGGGCCAACT 
CGAATTCTTC CCAATCTCTA TCTCGGCTGC CAGCGAGATG TCCTCAACAA GGAGCTGATG 
CAACAGAACG GGATTGGCTA TGTGCTAAAT GCCAGCAACA CCTGTCCAAA GCCTGACTTC 
ATACCCGAAT CTCACTTCCT GCGAGTGCCT GTGAATGACA GCTTTTGTGA GAAAATCCTG 
CCCTGGTTGG ACAAGTCTGT GGATTTCATT GAGAAAGCAA AAGCCTCCAA CGGCTGTGTG 
CTGATCCACT GCTTGGCTGG GATCTCCCGC TCGGCCACCA TTGCTATTGC CTATATCATG 
AAGAGGATGG ACATGTCTCT GGATGAGGCT TACAGATTTG TGAAAGAAAA AAGACCTACT 
ATATCTCCGA ACTTTAATTT TATGGGCCAA CTCATGGACT ATGAGAAGAC GATTAGTAGC 
CAGACTGGAA TGTCCGGGCC GAAGAGCAAA CTCAAGCTGC TGCACCTGGA CAAAGCCAGT 
GAGCCTGTGC CTGCAGCCTC AGAGGGCGGA CGGAAGAATG CACTGTCTCT CAGCCCACCC 
TGTGCCAACT CTACCTCAGA GGCAGTGGGG CAAAGGCTTG TGCATCCTGC AAGTGTGCCC 
AGCTTACAGC CTTCCCTCTT GGAGGACAGT CCGCTGGTAC AGGCGCTCAG TGGGCTCCAG 
CTGTCCTCAG AGAAGCTGGA AGACAGCAAC AGGCTCAAGC GTTCCTTCTC TCTCGATATC 
AAGTCTGTTT CGTATTCAGC CAGTGTGGCA GCGTCCTTAC ACGGCTTCTC GTCAGAGGAT 
GCTATGGAGT ACTACAAACC TTCCGCCACA CTGGATGGGA CCAGCAAGCT CTGCCAGTTC 
TCCCCCGTTC AGGAGGTATC AGAACAGACT CCAGAGACCA GCCCCGATAA GGAGGAGGCC 
CACATCCCCA GGCAGCCCCA AGCTACCAGA CCTTCAGAGA GCCAGACCAC ACGGCTGCAC 
TCAGTGAGAA CCAGCAGTAC TGGGTCTACC CAGAGGCCCT TCTTCTCGCC ACTGCATCGG 
AGCGGGAGTG TGGAGGACAA CTACCACACC AACTTCCTTT TTGGCCTTTC CACCAGCCAG 
CAGCACCTCA CCAAGTCTGC TGCAGGGCTT GGCCTCAAGG GCTGGCACTC AGACATTCTG 
CCTCCCCAGT CCTCTGCCCC TTCCCTGACC AGCGGTTGGT ATTTTGCTAC AGAGCCTTCA 
CACTTCTACT CTGCTTCAGC CATCTATGGA GGCAACGCCA GTTACTCTGC CTACAGCTGT 
AGCCAGCTGC CCACTTGCAG TGACCAAATC TATTCTGTTC GTAGGCGGCA GAAGCCTAGT 
GACAGAGCTG ACTCACGGCG GAGCTGGCAT GAAGAGAGCC CCTTTGAGAA GCAGTTTAAA 
CGCAGGAGCT GCCAAATGGA ATTTGGAGAG AGCATTATGT CAGAGAACAG GTCGAGGGAA 
GAACTGGGCA AAGTGGGGAG CCAATCTAGC TTTTCAGGAA GCATGGAGGT CATTGAGGTC 
TCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dusp16 ( XM_008763374.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008761596.1 Rattus norvegicus dual specificity phosphatase 16 (Dusp16), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa01820
Clone ID Related Accession (Same CDS sequence)	XM_008763374.2 , NM_001106624.2
Accession Version	XM_008763374.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1986bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity protein phosphatase 16 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008763374.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCATG AGATGACTGG AACTCAAATT GTTACTGAGA GGTTGGTGGC TCTGTTGGAA 
AGCGGCACCG AGAAAGTGCT GCTAATTGAC AGCCGGCCAT TTGTGGAGTA CAATACGTCC 
CACATTCTGG AAGCCATCAA TATCAACTGC TCCAAACTGA TGAAGCGAAG GCTGCAACAA 
GACAAAGTAT TAATTACAGA ACTCATCCAG CATTCTGCAA AACATAAGGT TGACATTGAC 
TGCAGTCAGA AGGTGGTAGT GTATGATCAG AGTTCCCAGG ATGTTGGTTC TCTGTCGTCA 
GACTGCTTTC TCACTGTGCT TCTGGGTAAG CTGGAGAAGA GCTTCAACTC TGTTCACCTG 
CTTGCAGGTG GGTTTGCTGA GTTCTCTCGT TGTTTCCCTG GCCTCTGTGA AGGAAAATCC 
ACTCTAGTCC CTACCTGCAT ATCTCAGCCT TGCCTACCTG TTGCCAACAC TGGGCCAACT 
CGAATTCTTC CCAATCTCTA TCTCGGCTGC CAGCGAGATG TCCTCAACAA GGAGCTGATG 
CAACAGAACG GGATTGGCTA TGTGCTAAAT GCCAGCAACA CCTGTCCAAA GCCTGACTTC 
ATACCCGAAT CTCACTTCCT GCGAGTGCCT GTGAATGACA GCTTTTGTGA GAAAATCCTG 
CCCTGGTTGG ACAAGTCTGT GGATTTCATT GAGAAAGCAA AAGCCTCCAA CGGCTGTGTG 
CTGATCCACT GCTTGGCTGG GATCTCCCGC TCGGCCACCA TTGCTATTGC CTATATCATG 
AAGAGGATGG ACATGTCTCT GGATGAGGCT TACAGATTTG TGAAAGAAAA AAGACCTACT 
ATATCTCCGA ACTTTAATTT TATGGGCCAA CTCATGGACT ATGAGAAGAC GATTAGTAGC 
CAGACTGGAA TGTCCGGGCC GAAGAGCAAA CTCAAGCTGC TGCACCTGGA CAAAGCCAGT 
GAGCCTGTGC CTGCAGCCTC AGAGGGCGGA CGGAAGAATG CACTGTCTCT CAGCCCACCC 
TGTGCCAACT CTACCTCAGA GGCAGTGGGG CAAAGGCTTG TGCATCCTGC AAGTGTGCCC 
AGCTTACAGC CTTCCCTCTT GGAGGACAGT CCGCTGGTAC AGGCGCTCAG TGGGCTCCAG 
CTGTCCTCAG AGAAGCTGGA AGACAGCAAC AGGCTCAAGC GTTCCTTCTC TCTCGATATC 
AAGTCTGTTT CGTATTCAGC CAGTGTGGCA GCGTCCTTAC ACGGCTTCTC GTCAGAGGAT 
GCTATGGAGT ACTACAAACC TTCCGCCACA CTGGATGGGA CCAGCAAGCT CTGCCAGTTC 
TCCCCCGTTC AGGAGGTATC AGAACAGACT CCAGAGACCA GCCCCGATAA GGAGGAGGCC 
CACATCCCCA GGCAGCCCCA AGCTACCAGA CCTTCAGAGA GCCAGACCAC ACGGCTGCAC 
TCAGTGAGAA CCAGCAGTAC TGGGTCTACC CAGAGGCCCT TCTTCTCGCC ACTGCATCGG 
AGCGGGAGTG TGGAGGACAA CTACCACACC AACTTCCTTT TTGGCCTTTC CACCAGCCAG 
CAGCACCTCA CCAAGTCTGC TGCAGGGCTT GGCCTCAAGG GCTGGCACTC AGACATTCTG 
CCTCCCCAGT CCTCTGCCCC TTCCCTGACC AGCGGTTGGT ATTTTGCTAC AGAGCCTTCA 
CACTTCTACT CTGCTTCAGC CATCTATGGA GGCAACGCCA GTTACTCTGC CTACAGCTGT 
AGCCAGCTGC CCACTTGCAG TGACCAAATC TATTCTGTTC GTAGGCGGCA GAAGCCTAGT 
GACAGAGCTG ACTCACGGCG GAGCTGGCAT GAAGAGAGCC CCTTTGAGAA GCAGTTTAAA 
CGCAGGAGCT GCCAAATGGA ATTTGGAGAG AGCATTATGT CAGAGAACAG GTCGAGGGAA 
GAACTGGGCA AAGTGGGGAG CCAATCTAGC TTTTCAGGAA GCATGGAGGT CATTGAGGTC 
TCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008761596.1
CDS	439..2424
Translation	MAHEMTGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVGSLSSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANTGPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLIHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFMGQLMDYEKTISSQTGMSGPKSKLKLLHLDKASEPVPAASEGGRKNALSLSPPCANSTSEAVGQRLVHPASVPSLQPSLLEDSPLVQALSGLQLSSEKLEDSNRLKRSFSLDIKSVSYSASVAASLHGFSSEDAMEYYKPSATLDGTSKLCQFSPVQEVSEQTPETSPDKEEAHIPRQPQATRPSESQTTRLHSVRTSSTGSTQRPFFSPLHRSGSVEDNYHTNFLFGLSTSQQHLTKSAAGLGLKGWHSDILPPQSSAPSLTSGWYFATEPSHFYSASAIYGGNASYSAYSCSQLPTCSDQIYSVRRRQKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSMEVIEVS

Target ORF information:

RefSeq Version	XM_008763374.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity phosphatase 16 (Dusp16), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008763374.2

ORF Insert Sequence:

ATGGCCCATG AGATGACTGG AACTCAAATT GTTACTGAGA GGTTGGTGGC TCTGTTGGAA 
AGCGGCACCG AGAAAGTGCT GCTAATTGAC AGCCGGCCAT TTGTGGAGTA CAATACGTCC 
CACATTCTGG AAGCCATCAA TATCAACTGC TCCAAACTGA TGAAGCGAAG GCTGCAACAA 
GACAAAGTAT TAATTACAGA ACTCATCCAG CATTCTGCAA AACATAAGGT TGACATTGAC 
TGCAGTCAGA AGGTGGTAGT GTATGATCAG AGTTCCCAGG ATGTTGGTTC TCTGTCGTCA 
GACTGCTTTC TCACTGTGCT TCTGGGTAAG CTGGAGAAGA GCTTCAACTC TGTTCACCTG 
CTTGCAGGTG GGTTTGCTGA GTTCTCTCGT TGTTTCCCTG GCCTCTGTGA AGGAAAATCC 
ACTCTAGTCC CTACCTGCAT ATCTCAGCCT TGCCTACCTG TTGCCAACAC TGGGCCAACT 
CGAATTCTTC CCAATCTCTA TCTCGGCTGC CAGCGAGATG TCCTCAACAA GGAGCTGATG 
CAACAGAACG GGATTGGCTA TGTGCTAAAT GCCAGCAACA CCTGTCCAAA GCCTGACTTC 
ATACCCGAAT CTCACTTCCT GCGAGTGCCT GTGAATGACA GCTTTTGTGA GAAAATCCTG 
CCCTGGTTGG ACAAGTCTGT GGATTTCATT GAGAAAGCAA AAGCCTCCAA CGGCTGTGTG 
CTGATCCACT GCTTGGCTGG GATCTCCCGC TCGGCCACCA TTGCTATTGC CTATATCATG 
AAGAGGATGG ACATGTCTCT GGATGAGGCT TACAGATTTG TGAAAGAAAA AAGACCTACT 
ATATCTCCGA ACTTTAATTT TATGGGCCAA CTCATGGACT ATGAGAAGAC GATTAGTAGC 
CAGACTGGAA TGTCCGGGCC GAAGAGCAAA CTCAAGCTGC TGCACCTGGA CAAAGCCAGT 
GAGCCTGTGC CTGCAGCCTC AGAGGGCGGA CGGAAGAATG CACTGTCTCT CAGCCCACCC 
TGTGCCAACT CTACCTCAGA GGCAGTGGGG CAAAGGCTTG TGCATCCTGC AAGTGTGCCC 
AGCTTACAGC CTTCCCTCTT GGAGGACAGT CCGCTGGTAC AGGCGCTCAG TGGGCTCCAG 
CTGTCCTCAG AGAAGCTGGA AGACAGCAAC AGGCTCAAGC GTTCCTTCTC TCTCGATATC 
AAGTCTGTTT CGTATTCAGC CAGTGTGGCA GCGTCCTTAC ACGGCTTCTC GTCAGAGGAT 
GCTATGGAGT ACTACAAACC TTCCGCCACA CTGGATGGGA CCAGCAAGCT CTGCCAGTTC 
TCCCCCGTTC AGGAGGTATC AGAACAGACT CCAGAGACCA GCCCCGATAA GGAGGAGGCC 
CACATCCCCA GGCAGCCCCA AGCTACCAGA CCTTCAGAGA GCCAGACCAC ACGGCTGCAC 
TCAGTGAGAA CCAGCAGTAC TGGGTCTACC CAGAGGCCCT TCTTCTCGCC ACTGCATCGG 
AGCGGGAGTG TGGAGGACAA CTACCACACC AACTTCCTTT TTGGCCTTTC CACCAGCCAG 
CAGCACCTCA CCAAGTCTGC TGCAGGGCTT GGCCTCAAGG GCTGGCACTC AGACATTCTG 
CCTCCCCAGT CCTCTGCCCC TTCCCTGACC AGCGGTTGGT ATTTTGCTAC AGAGCCTTCA 
CACTTCTACT CTGCTTCAGC CATCTATGGA GGCAACGCCA GTTACTCTGC CTACAGCTGT 
AGCCAGCTGC CCACTTGCAG TGACCAAATC TATTCTGTTC GTAGGCGGCA GAAGCCTAGT 
GACAGAGCTG ACTCACGGCG GAGCTGGCAT GAAGAGAGCC CCTTTGAGAA GCAGTTTAAA 
CGCAGGAGCT GCCAAATGGA ATTTGGAGAG AGCATTATGT CAGAGAACAG GTCGAGGGAA 
GAACTGGGCA AAGTGGGGAG CCAATCTAGC TTTTCAGGAA GCATGGAGGT CATTGAGGTC 
TCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The family-wide structure and function of human dual-specificity protein phosphatases.
Acta crystallographica. Section D, Biological crystallography70(Pt 2)421-35(2014 Feb)
Jeong DG,Wei CH,Ku B,Jeon TJ,Chien PN,Kim JK,Park SY,Hwang HS,Ryu SY,Park H,Kim DS,Kim SJ,Ryu SE

PI3K/Akt-independent negative regulation of JNK signaling by MKP-7 after cerebral ischemia in rat hippocampus.
BMC neuroscience141(2013 Jan)
Zhu J,Shen W,Gao L,Gu H,Shen S,Wang Y,Wu H,Guo J

Mechanisms and functions of p38 MAPK signalling.
The Biochemical journal429(3)403-17(2010 Aug)
Cuadrado A,Nebreda AR

Regulation of MAP kinases by MAP kinase phosphatases.
Biochimica et biophysica acta1773(8)1227-37(2007 Aug)
Kondoh K,Nishida E

MKP-7, a novel mitogen-activated protein kinase phosphatase, functions as a shuttle protein.
The Journal of biological chemistry276(42)39002-11(2001 Oct)
Masuda K,Shima H,Watanabe M,Kikuchi K

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Dusp16 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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