Lag3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lag3
Entrez Gene ID	297596
Full Name	lymphocyte activating 3
Synonyms	CD223
General protein information	Preferred Names lymphocyte activating 3 Names lymphocyte activation gene 3 protein LAG-3 lymphocyte-activation gene 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q42
Summary	mouse homolog regulates the proliferation of activated T-cells [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017592591.1	XP_017448080.1	lymphocyte activation gene 3 protein isoform X2
XM_017592592.1	XP_017448081.1	lymphocyte activation gene 3 protein isoform X3
XM_008763282.2	XP_008761504.1	lymphocyte activation gene 3 protein isoform X1
XM_008763283.2	XP_008761505.1	lymphocyte activation gene 3 protein isoform X2
XM_006237348.3	XP_006237410.1	lymphocyte activation gene 3 protein isoform X3
NM_212513.2	NP_997678.2	lymphocyte activation gene 3 protein precursor

Pathways from BioSystems

Homologies

	LAG3	XP_001108923.1
Bos taurus (cattle)	LAG3	NP_001232878.1
Mus musculus (house mouse)	Lag3	NP_032505.1
Rattus norvegicus (Norway rat)	Lag3	NP_997678.2
Gallus gallus (chicken)	LAG3	XP_416510.2
Pan troglodytes (chimpanzee)	LAG3	XP_508966.2
Xenopus tropicalis (tropical clawed frog)	lag3	XP_004915830.1
Homo sapiens (human)	LAG3	NP_002277.4

Gene Ontology
Bibliography

Related articles in PubMed

LAG-3 regulates plasmacytoid dendritic cell homeostasis.
Workman CJ, Wang Y, El Kasmi KC, Pardoll DM, Murray PJ, Drake CG, Vignali DA
Journal of immunology (Baltimore, Md. : 1950)182(4)1885-91(2009 Feb)

Depletion of LAG-3 positive cells in cardiac allograft reveals their role in rejection and tolerance.
Haudebourg T, Dugast AS, Coulon F, Usal C, Triebel F, Vanhove B
Transplantation84(11)1500-6(2007 Dec)

A soluble form of lymphocyte activation gene-3 (IMP321) induces activation of a large range of human effector cytotoxic cells.
Brignone C, Grygar C, Marcu M, Sch?kel K, Triebel F
Journal of immunology (Baltimore, Md. : 1950)179(6)4202-11(2007 Sep)

Role of LAG-3 in regulatory T cells.
Huang CT, Workman CJ, Flies D, Pan X, Marson AL, Zhou G, Hipkiss EL, Ravi S, Kowalski J, Levitsky HI, Powell JD, Pardoll DM, Drake CG, Vignali DA
Immunity21(4)503-13(2004 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Targeting LAG-3-positive cells with cytotoxic antibodies is immunosuppressive in transplantation by depleting effectors T cells
Title: Depletion of LAG-3 positive cells in cardiac allograft reveals their role in rejection and tolerance.

LAG-3 binds to a minority of histocompatibility class II-positive cells in peripheral blood mononuclear leukocytes, including all myeloid dendritic cells, and a small fraction of monocytes.
Title: A soluble form of lymphocyte activation gene-3 (IMP321) induces activation of a large range of human effector cytotoxic cells.

cloning and mRNA expression; Lag3 mRNA was mainly expressed in lymphoid tissues
Title: Cloning of rat lymphocyte activation gene-3 (Lag3; CD223) cDNA and its mRNA expression in rat tissues.

The following Lag3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lag3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa05754	NM_212513.2 Latest version!	Rattus norvegicus lymphocyte activating 3 (Lag3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa05754	XM_008763282.2 Latest version!	Rattus norvegicus lymphocyte activating 3 (Lag3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa27758	XM_017592592.1 Latest version!	Rattus norvegicus lymphocyte activating 3 (Lag3), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa27758	XM_006237348.3 Latest version!	Rattus norvegicus lymphocyte activating 3 (Lag3), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa27757	XM_008763283.2 Latest version!	Rattus norvegicus lymphocyte activating 3 (Lag3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa27757	XM_017592591.1 Latest version!	Rattus norvegicus lymphocyte activating 3 (Lag3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lag3 ( NM_212513.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_997678.2 Rattus norvegicus lymphocyte activating 3 (Lag3), mRNA.

Price & Availability↑

CloneID	ORa05754
Clone ID Related Accession (Same CDS sequence)	XM_008763282.2 , NM_212513.2
Accession Version	NM_212513.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1578bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	lymphocyte activation gene 3 protein precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC091201.1. On Mar 27, 2005 this sequence version replaced NM_212513.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC091201.1, AY230414.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAGGCAGG ATCTGTTCCT TGACCTTTTG CTTCTGCAGC TGCTTTGGGA AGCTCCAGTT 
GTGTCTTCAG GGCCTGGGAA AGAGCTCTCC GTGGTGTGGG CCCAGGAGGG AGCTCCTGTC 
CATCTTCCCT GCAGCCTCGA ATTTCCCCAC CTGGATCCCA ACTTTCTGCG AAGAGGATGG 
GTCACCTGGC AACATCGACC AGACAGTGAC CAACCCGCTT CCATCCCGGC CCTTGACCTT 
CTCCAGGGAA TGCCCTCGAC TAGGAGACAC CCACCCCATC GCTACACGGT GCTGAGTGTG 
GCTCCAGGAG GCCTGCGCAG CGGGAGGCAG CCCCTGCTAT CCCACGTGCA GCTGGAGAAG 
CGTGGCCCCC AGCGCGGGGA CTTCTCTCTG TGGTTGCGCC CAGCTACGCG CAAAGATGCG 
GGCGAGTACC ACGCCTTCGT GCGCCTCCCG GACCGCGACT TCTCCTGCAG CCTCCGCCTG 
CGCGTCGGCC AGGCCTCGAT GATTGCCAGT CCCCCAGGAA CCCTCAAGCC GTCTGATTGG 
GTCATTTTGA ACTGCTCCTT CAGTCGTCCT GACCGCCCAG TCTCTGTGCA CTGGTTCCAG 
GGCCAAAGCC GAGTGCCCGT CCACAATTCA CCCCGTCATT ATCTAGCTGA AAGTTTCCTC 
TTACTGCCCC AAGTCAGCCC ACTGGATTCC GGGACCTGGG GCTGTGTCCT CACCTACAGA 
GATGGCTTCA ATGTCTCCAT CACGTACAAC CTCAAGGTTC AGGGTCTGGA ACCTGTAGCC 
CCTTTGACAG TGTACGCTGC TGAAGGTTCT AGGGTGGAGC TGCCCTGTCA CTTGCCTCCC 
GTTGTGGGGA CCCCTTCTTT GCTCATTGCC AAGTGGACTC CTCCTGGGGG AGGTCCTGAG 
CTCCCGGTGA CTGGAAAGAG TGGCAATTTT ACCCTTCAAC TTGAGAATGT GGGTCGGGCA 
CAGGCTGGGA CCTACACCTG CAGCATCCAT CTGCAGGGGC GGCAGCTCAG TGCGGCTGTG 
ACGTTGGCAG TCATCACAGT GACTCCTAAA TCCTTCGGGT TACCTGGCTC CCCGCAGAAG 
CTGTTATGTG AGGTAGTCCC GGCATCTGGA GAAGGAAGAT TTGTGTGGCG CCCCCTCAGC 
GATCTGTCCA GGAGTTCCCT GGGCCCTGTG CTGGAGTTGC AGGAGGCCAA GCTTCTGGCT 
GAGCAATGGC AGTGTCAGCT GTATGAGGGC CAGAAACTTC TTGGAGCAAC AGTGTACACC 
GCAGAGTCTA GCTCAGGCGC CTGGAGTGCT AAGAGAATCT CAGGTGACCT TAAAGGAGGC 
CATCTCTTCC TCTCTCTCAT CCTTGGTGCC CTTGCCTTGT TCCTCTTGGT GACCGGGGCC 
TTTGGCTTTC ACCTGTGGAG AAGACAGTTG CTACGGAGAA GATTTTCTGC CTTAGAGCAT 
GGGATTCGCC CACCTCCGGT TCAGAGTAAG ATAGAGGAGC TGGAGCGAGA ACCGGAGACC 
GAGATGGAAC CAGAGACAGA GCCCGATCCG GAGCCTCAGC CGGAGCCCGA GCTGGAACCA 
GAGTCCAGGC AGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997678.2
CDS	123..1700
Translation	MRQDLFLDLLLLQLLWEAPVVSSGPGKELSVVWAQEGAPVHLPCSLEFPHLDPNFLRRGWVTWQHRPDSDQPASIPALDLLQGMPSTRRHPPHRYTVLSVAPGGLRSGRQPLLSHVQLEKRGPQRGDFSLWLRPATRKDAGEYHAFVRLPDRDFSCSLRLRVGQASMIASPPGTLKPSDWVILNCSFSRPDRPVSVHWFQGQSRVPVHNSPRHYLAESFLLLPQVSPLDSGTWGCVLTYRDGFNVSITYNLKVQGLEPVAPLTVYAAEGSRVELPCHLPPVVGTPSLLIAKWTPPGGGPELPVTGKSGNFTLQLENVGRAQAGTYTCSIHLQGRQLSAAVTLAVITVTPKSFGLPGSPQKLLCEVVPASGEGRFVWRPLSDLSRSSLGPVLELQEAKLLAEQWQCQLYEGQKLLGATVYTAESSSGAWSAKRISGDLKGGHLFLSLILGALALFLLVTGAFGFHLWRRQLLRRRFSALEHGIRPPPVQSKIEELEREPETEMEPETEPDPEPQPEPELEPESRQL

Target ORF information:

RefSeq Version	NM_212513.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lymphocyte activating 3 (Lag3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_212513.2

ORF Insert Sequence:

ATGAGGCAGG ATCTGTTCCT TGACCTTTTG CTTCTGCAGC TGCTTTGGGA AGCTCCAGTT 
GTGTCTTCAG GGCCTGGGAA AGAGCTCTCC GTGGTGTGGG CCCAGGAGGG AGCTCCTGTC 
CATCTTCCCT GCAGCCTCGA ATTTCCCCAC CTGGATCCCA ACTTTCTGCG AAGAGGATGG 
GTCACCTGGC AACATCGACC AGACAGTGAC CAACCCGCTT CCATCCCGGC CCTTGACCTT 
CTCCAGGGAA TGCCCTCGAC TAGGAGACAC CCACCCCATC GCTACACGGT GCTGAGTGTG 
GCTCCAGGAG GCCTGCGCAG CGGGAGGCAG CCCCTGCTAT CCCACGTGCA GCTGGAGAAG 
CGTGGCCCCC AGCGCGGGGA CTTCTCTCTG TGGTTGCGCC CAGCTACGCG CAAAGATGCG 
GGCGAGTACC ACGCCTTCGT GCGCCTCCCG GACCGCGACT TCTCCTGCAG CCTCCGCCTG 
CGCGTCGGCC AGGCCTCGAT GATTGCCAGT CCCCCAGGAA CCCTCAAGCC GTCTGATTGG 
GTCATTTTGA ACTGCTCCTT CAGTCGTCCT GACCGCCCAG TCTCTGTGCA CTGGTTCCAG 
GGCCAAAGCC GAGTGCCCGT CCACAATTCA CCCCGTCATT ATCTAGCTGA AAGTTTCCTC 
TTACTGCCCC AAGTCAGCCC ACTGGATTCC GGGACCTGGG GCTGTGTCCT CACCTACAGA 
GATGGCTTCA ATGTCTCCAT CACGTACAAC CTCAAGGTTC AGGGTCTGGA ACCTGTAGCC 
CCTTTGACAG TGTACGCTGC TGAAGGTTCT AGGGTGGAGC TGCCCTGTCA CTTGCCTCCC 
GTTGTGGGGA CCCCTTCTTT GCTCATTGCC AAGTGGACTC CTCCTGGGGG AGGTCCTGAG 
CTCCCGGTGA CTGGAAAGAG TGGCAATTTT ACCCTTCAAC TTGAGAATGT GGGTCGGGCA 
CAGGCTGGGA CCTACACCTG CAGCATCCAT CTGCAGGGGC GGCAGCTCAG TGCGGCTGTG 
ACGTTGGCAG TCATCACAGT GACTCCTAAA TCCTTCGGGT TACCTGGCTC CCCGCAGAAG 
CTGTTATGTG AGGTAGTCCC GGCATCTGGA GAAGGAAGAT TTGTGTGGCG CCCCCTCAGC 
GATCTGTCCA GGAGTTCCCT GGGCCCTGTG CTGGAGTTGC AGGAGGCCAA GCTTCTGGCT 
GAGCAATGGC AGTGTCAGCT GTATGAGGGC CAGAAACTTC TTGGAGCAAC AGTGTACACC 
GCAGAGTCTA GCTCAGGCGC CTGGAGTGCT AAGAGAATCT CAGGTGACCT TAAAGGAGGC 
CATCTCTTCC TCTCTCTCAT CCTTGGTGCC CTTGCCTTGT TCCTCTTGGT GACCGGGGCC 
TTTGGCTTTC ACCTGTGGAG AAGACAGTTG CTACGGAGAA GATTTTCTGC CTTAGAGCAT 
GGGATTCGCC CACCTCCGGT TCAGAGTAAG ATAGAGGAGC TGGAGCGAGA ACCGGAGACC 
GAGATGGAAC CAGAGACAGA GCCCGATCCG GAGCCTCAGC CGGAGCCCGA GCTGGAACCA 
GAGTCCAGGC AGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lag3 ( XM_008763282.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008761504.1 Rattus norvegicus lymphocyte activating 3 (Lag3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa05754
Clone ID Related Accession (Same CDS sequence)	XM_008763282.2 , NM_212513.2
Accession Version	XM_008763282.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1578bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lymphocyte activation gene 3 protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008763282.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGCAGG ATCTGTTCCT TGACCTTTTG CTTCTGCAGC TGCTTTGGGA AGCTCCAGTT 
GTGTCTTCAG GGCCTGGGAA AGAGCTCTCC GTGGTGTGGG CCCAGGAGGG AGCTCCTGTC 
CATCTTCCCT GCAGCCTCGA ATTTCCCCAC CTGGATCCCA ACTTTCTGCG AAGAGGATGG 
GTCACCTGGC AACATCGACC AGACAGTGAC CAACCCGCTT CCATCCCGGC CCTTGACCTT 
CTCCAGGGAA TGCCCTCGAC TAGGAGACAC CCACCCCATC GCTACACGGT GCTGAGTGTG 
GCTCCAGGAG GCCTGCGCAG CGGGAGGCAG CCCCTGCTAT CCCACGTGCA GCTGGAGAAG 
CGTGGCCCCC AGCGCGGGGA CTTCTCTCTG TGGTTGCGCC CAGCTACGCG CAAAGATGCG 
GGCGAGTACC ACGCCTTCGT GCGCCTCCCG GACCGCGACT TCTCCTGCAG CCTCCGCCTG 
CGCGTCGGCC AGGCCTCGAT GATTGCCAGT CCCCCAGGAA CCCTCAAGCC GTCTGATTGG 
GTCATTTTGA ACTGCTCCTT CAGTCGTCCT GACCGCCCAG TCTCTGTGCA CTGGTTCCAG 
GGCCAAAGCC GAGTGCCCGT CCACAATTCA CCCCGTCATT ATCTAGCTGA AAGTTTCCTC 
TTACTGCCCC AAGTCAGCCC ACTGGATTCC GGGACCTGGG GCTGTGTCCT CACCTACAGA 
GATGGCTTCA ATGTCTCCAT CACGTACAAC CTCAAGGTTC AGGGTCTGGA ACCTGTAGCC 
CCTTTGACAG TGTACGCTGC TGAAGGTTCT AGGGTGGAGC TGCCCTGTCA CTTGCCTCCC 
GTTGTGGGGA CCCCTTCTTT GCTCATTGCC AAGTGGACTC CTCCTGGGGG AGGTCCTGAG 
CTCCCGGTGA CTGGAAAGAG TGGCAATTTT ACCCTTCAAC TTGAGAATGT GGGTCGGGCA 
CAGGCTGGGA CCTACACCTG CAGCATCCAT CTGCAGGGGC GGCAGCTCAG TGCGGCTGTG 
ACGTTGGCAG TCATCACAGT GACTCCTAAA TCCTTCGGGT TACCTGGCTC CCCGCAGAAG 
CTGTTATGTG AGGTAGTCCC GGCATCTGGA GAAGGAAGAT TTGTGTGGCG CCCCCTCAGC 
GATCTGTCCA GGAGTTCCCT GGGCCCTGTG CTGGAGTTGC AGGAGGCCAA GCTTCTGGCT 
GAGCAATGGC AGTGTCAGCT GTATGAGGGC CAGAAACTTC TTGGAGCAAC AGTGTACACC 
GCAGAGTCTA GCTCAGGCGC CTGGAGTGCT AAGAGAATCT CAGGTGACCT TAAAGGAGGC 
CATCTCTTCC TCTCTCTCAT CCTTGGTGCC CTTGCCTTGT TCCTCTTGGT GACCGGGGCC 
TTTGGCTTTC ACCTGTGGAG AAGACAGTTG CTACGGAGAA GATTTTCTGC CTTAGAGCAT 
GGGATTCGCC CACCTCCGGT TCAGAGTAAG ATAGAGGAGC TGGAGCGAGA ACCGGAGACC 
GAGATGGAAC CAGAGACAGA GCCCGATCCG GAGCCTCAGC CGGAGCCCGA GCTGGAACCA 
GAGTCCAGGC AGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008761504.1
CDS	234..1811
Translation	MRQDLFLDLLLLQLLWEAPVVSSGPGKELSVVWAQEGAPVHLPCSLEFPHLDPNFLRRGWVTWQHRPDSDQPASIPALDLLQGMPSTRRHPPHRYTVLSVAPGGLRSGRQPLLSHVQLEKRGPQRGDFSLWLRPATRKDAGEYHAFVRLPDRDFSCSLRLRVGQASMIASPPGTLKPSDWVILNCSFSRPDRPVSVHWFQGQSRVPVHNSPRHYLAESFLLLPQVSPLDSGTWGCVLTYRDGFNVSITYNLKVQGLEPVAPLTVYAAEGSRVELPCHLPPVVGTPSLLIAKWTPPGGGPELPVTGKSGNFTLQLENVGRAQAGTYTCSIHLQGRQLSAAVTLAVITVTPKSFGLPGSPQKLLCEVVPASGEGRFVWRPLSDLSRSSLGPVLELQEAKLLAEQWQCQLYEGQKLLGATVYTAESSSGAWSAKRISGDLKGGHLFLSLILGALALFLLVTGAFGFHLWRRQLLRRRFSALEHGIRPPPVQSKIEELEREPETEMEPETEPDPEPQPEPELEPESRQL

Target ORF information:

RefSeq Version	XM_008763282.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lymphocyte activating 3 (Lag3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008763282.2

ORF Insert Sequence:

ATGAGGCAGG ATCTGTTCCT TGACCTTTTG CTTCTGCAGC TGCTTTGGGA AGCTCCAGTT 
GTGTCTTCAG GGCCTGGGAA AGAGCTCTCC GTGGTGTGGG CCCAGGAGGG AGCTCCTGTC 
CATCTTCCCT GCAGCCTCGA ATTTCCCCAC CTGGATCCCA ACTTTCTGCG AAGAGGATGG 
GTCACCTGGC AACATCGACC AGACAGTGAC CAACCCGCTT CCATCCCGGC CCTTGACCTT 
CTCCAGGGAA TGCCCTCGAC TAGGAGACAC CCACCCCATC GCTACACGGT GCTGAGTGTG 
GCTCCAGGAG GCCTGCGCAG CGGGAGGCAG CCCCTGCTAT CCCACGTGCA GCTGGAGAAG 
CGTGGCCCCC AGCGCGGGGA CTTCTCTCTG TGGTTGCGCC CAGCTACGCG CAAAGATGCG 
GGCGAGTACC ACGCCTTCGT GCGCCTCCCG GACCGCGACT TCTCCTGCAG CCTCCGCCTG 
CGCGTCGGCC AGGCCTCGAT GATTGCCAGT CCCCCAGGAA CCCTCAAGCC GTCTGATTGG 
GTCATTTTGA ACTGCTCCTT CAGTCGTCCT GACCGCCCAG TCTCTGTGCA CTGGTTCCAG 
GGCCAAAGCC GAGTGCCCGT CCACAATTCA CCCCGTCATT ATCTAGCTGA AAGTTTCCTC 
TTACTGCCCC AAGTCAGCCC ACTGGATTCC GGGACCTGGG GCTGTGTCCT CACCTACAGA 
GATGGCTTCA ATGTCTCCAT CACGTACAAC CTCAAGGTTC AGGGTCTGGA ACCTGTAGCC 
CCTTTGACAG TGTACGCTGC TGAAGGTTCT AGGGTGGAGC TGCCCTGTCA CTTGCCTCCC 
GTTGTGGGGA CCCCTTCTTT GCTCATTGCC AAGTGGACTC CTCCTGGGGG AGGTCCTGAG 
CTCCCGGTGA CTGGAAAGAG TGGCAATTTT ACCCTTCAAC TTGAGAATGT GGGTCGGGCA 
CAGGCTGGGA CCTACACCTG CAGCATCCAT CTGCAGGGGC GGCAGCTCAG TGCGGCTGTG 
ACGTTGGCAG TCATCACAGT GACTCCTAAA TCCTTCGGGT TACCTGGCTC CCCGCAGAAG 
CTGTTATGTG AGGTAGTCCC GGCATCTGGA GAAGGAAGAT TTGTGTGGCG CCCCCTCAGC 
GATCTGTCCA GGAGTTCCCT GGGCCCTGTG CTGGAGTTGC AGGAGGCCAA GCTTCTGGCT 
GAGCAATGGC AGTGTCAGCT GTATGAGGGC CAGAAACTTC TTGGAGCAAC AGTGTACACC 
GCAGAGTCTA GCTCAGGCGC CTGGAGTGCT AAGAGAATCT CAGGTGACCT TAAAGGAGGC 
CATCTCTTCC TCTCTCTCAT CCTTGGTGCC CTTGCCTTGT TCCTCTTGGT GACCGGGGCC 
TTTGGCTTTC ACCTGTGGAG AAGACAGTTG CTACGGAGAA GATTTTCTGC CTTAGAGCAT 
GGGATTCGCC CACCTCCGGT TCAGAGTAAG ATAGAGGAGC TGGAGCGAGA ACCGGAGACC 
GAGATGGAAC CAGAGACAGA GCCCGATCCG GAGCCTCAGC CGGAGCCCGA GCTGGAACCA 
GAGTCCAGGC AGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lag3 ( XM_017592592.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017448081.1 Rattus norvegicus lymphocyte activating 3 (Lag3), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa27758
Clone ID Related Accession (Same CDS sequence)	XM_017592592.1 , XM_006237348.3
Accession Version	XM_017592592.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1329bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lymphocyte activation gene 3 protein isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCTCGA CTAGGAGACA CCCACCCCAT CGCTACACGG TGCTGAGTGT GGCTCCAGGA 
GGCCTGCGCA GCGGGAGGCA GCCCCTGCTA TCCCACGTGC AGCTGGAGAA GCGTGGCCCC 
CAGCGCGGGG ACTTCTCTCT GTGGTTGCGC CCAGCTACGC GCAAAGATGC GGGCGAGTAC 
CACGCCTTCG TGCGCCTCCC GGACCGCGAC TTCTCCTGCA GCCTCCGCCT GCGCGTCGGC 
CAGGCCTCGA TGATTGCCAG TCCCCCAGGA ACCCTCAAGC CGTCTGATTG GGTCATTTTG 
AACTGCTCCT TCAGTCGTCC TGACCGCCCA GTCTCTGTGC ACTGGTTCCA GGGCCAAAGC 
CGAGTGCCCG TCCACAATTC ACCCCGTCAT TATCTAGCTG AAAGTTTCCT CTTACTGCCC 
CAAGTCAGCC CACTGGATTC CGGGACCTGG GGCTGTGTCC TCACCTACAG AGATGGCTTC 
AATGTCTCCA TCACGTACAA CCTCAAGGTT CAGGGTCTGG AACCTGTAGC CCCTTTGACA 
GTGTACGCTG CTGAAGGTTC TAGGGTGGAG CTGCCCTGTC ACTTGCCTCC CGTTGTGGGG 
ACCCCTTCTT TGCTCATTGC CAAGTGGACT CCTCCTGGGG GAGGTCCTGA GCTCCCGGTG 
ACTGGAAAGA GTGGCAATTT TACCCTTCAA CTTGAGAATG TGGGTCGGGC ACAGGCTGGG 
ACCTACACCT GCAGCATCCA TCTGCAGGGG CGGCAGCTCA GTGCGGCTGT GACGTTGGCA 
GTCATCACAG TGACTCCTAA ATCCTTCGGG TTACCTGGCT CCCCGCAGAA GCTGTTATGT 
GAGGTAGTCC CGGCATCTGG AGAAGGAAGA TTTGTGTGGC GCCCCCTCAG CGATCTGTCC 
AGGAGTTCCC TGGGCCCTGT GCTGGAGTTG CAGGAGGCCA AGCTTCTGGC TGAGCAATGG 
CAGTGTCAGC TGTATGAGGG CCAGAAACTT CTTGGAGCAA CAGTGTACAC CGCAGAGTCT 
AGCTCAGGCG CCTGGAGTGC TAAGAGAATC TCAGGTGACC TTAAAGGAGG CCATCTCTTC 
CTCTCTCTCA TCCTTGGTGC CCTTGCCTTG TTCCTCTTGG TGACCGGGGC CTTTGGCTTT 
CACCTGTGGA GAAGACAGTT GCTACGGAGA AGATTTTCTG CCTTAGAGCA TGGGATTCGC 
CCACCTCCGG TTCAGAGTAA GATAGAGGAG CTGGAGCGAG AACCGGAGAC CGAGATGGAA 
CCAGAGACAG AGCCCGATCC GGAGCCTCAG CCGGAGCCCG AGCTGGAACC AGAGTCCAGG 
CAGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017448081.1
CDS	352..1680
Translation	MPSTRRHPPHRYTVLSVAPGGLRSGRQPLLSHVQLEKRGPQRGDFSLWLRPATRKDAGEYHAFVRLPDRDFSCSLRLRVGQASMIASPPGTLKPSDWVILNCSFSRPDRPVSVHWFQGQSRVPVHNSPRHYLAESFLLLPQVSPLDSGTWGCVLTYRDGFNVSITYNLKVQGLEPVAPLTVYAAEGSRVELPCHLPPVVGTPSLLIAKWTPPGGGPELPVTGKSGNFTLQLENVGRAQAGTYTCSIHLQGRQLSAAVTLAVITVTPKSFGLPGSPQKLLCEVVPASGEGRFVWRPLSDLSRSSLGPVLELQEAKLLAEQWQCQLYEGQKLLGATVYTAESSSGAWSAKRISGDLKGGHLFLSLILGALALFLLVTGAFGFHLWRRQLLRRRFSALEHGIRPPPVQSKIEELEREPETEMEPETEPDPEPQPEPELEPESRQL

Target ORF information:

RefSeq Version	XM_017592592.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lymphocyte activating 3 (Lag3), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017592592.1

ORF Insert Sequence:

ATGCCCTCGA CTAGGAGACA CCCACCCCAT CGCTACACGG TGCTGAGTGT GGCTCCAGGA 
GGCCTGCGCA GCGGGAGGCA GCCCCTGCTA TCCCACGTGC AGCTGGAGAA GCGTGGCCCC 
CAGCGCGGGG ACTTCTCTCT GTGGTTGCGC CCAGCTACGC GCAAAGATGC GGGCGAGTAC 
CACGCCTTCG TGCGCCTCCC GGACCGCGAC TTCTCCTGCA GCCTCCGCCT GCGCGTCGGC 
CAGGCCTCGA TGATTGCCAG TCCCCCAGGA ACCCTCAAGC CGTCTGATTG GGTCATTTTG 
AACTGCTCCT TCAGTCGTCC TGACCGCCCA GTCTCTGTGC ACTGGTTCCA GGGCCAAAGC 
CGAGTGCCCG TCCACAATTC ACCCCGTCAT TATCTAGCTG AAAGTTTCCT CTTACTGCCC 
CAAGTCAGCC CACTGGATTC CGGGACCTGG GGCTGTGTCC TCACCTACAG AGATGGCTTC 
AATGTCTCCA TCACGTACAA CCTCAAGGTT CAGGGTCTGG AACCTGTAGC CCCTTTGACA 
GTGTACGCTG CTGAAGGTTC TAGGGTGGAG CTGCCCTGTC ACTTGCCTCC CGTTGTGGGG 
ACCCCTTCTT TGCTCATTGC CAAGTGGACT CCTCCTGGGG GAGGTCCTGA GCTCCCGGTG 
ACTGGAAAGA GTGGCAATTT TACCCTTCAA CTTGAGAATG TGGGTCGGGC ACAGGCTGGG 
ACCTACACCT GCAGCATCCA TCTGCAGGGG CGGCAGCTCA GTGCGGCTGT GACGTTGGCA 
GTCATCACAG TGACTCCTAA ATCCTTCGGG TTACCTGGCT CCCCGCAGAA GCTGTTATGT 
GAGGTAGTCC CGGCATCTGG AGAAGGAAGA TTTGTGTGGC GCCCCCTCAG CGATCTGTCC 
AGGAGTTCCC TGGGCCCTGT GCTGGAGTTG CAGGAGGCCA AGCTTCTGGC TGAGCAATGG 
CAGTGTCAGC TGTATGAGGG CCAGAAACTT CTTGGAGCAA CAGTGTACAC CGCAGAGTCT 
AGCTCAGGCG CCTGGAGTGC TAAGAGAATC TCAGGTGACC TTAAAGGAGG CCATCTCTTC 
CTCTCTCTCA TCCTTGGTGC CCTTGCCTTG TTCCTCTTGG TGACCGGGGC CTTTGGCTTT 
CACCTGTGGA GAAGACAGTT GCTACGGAGA AGATTTTCTG CCTTAGAGCA TGGGATTCGC 
CCACCTCCGG TTCAGAGTAA GATAGAGGAG CTGGAGCGAG AACCGGAGAC CGAGATGGAA 
CCAGAGACAG AGCCCGATCC GGAGCCTCAG CCGGAGCCCG AGCTGGAACC AGAGTCCAGG 
CAGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lag3 ( XM_006237348.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006237410.1 Rattus norvegicus lymphocyte activating 3 (Lag3), transcript variant X4, mRNA.

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CloneID	ORa27758
Clone ID Related Accession (Same CDS sequence)	XM_017592592.1 , XM_006237348.3
Accession Version	XM_006237348.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1329bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lymphocyte activation gene 3 protein isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006237348.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCTCGA CTAGGAGACA CCCACCCCAT CGCTACACGG TGCTGAGTGT GGCTCCAGGA 
GGCCTGCGCA GCGGGAGGCA GCCCCTGCTA TCCCACGTGC AGCTGGAGAA GCGTGGCCCC 
CAGCGCGGGG ACTTCTCTCT GTGGTTGCGC CCAGCTACGC GCAAAGATGC GGGCGAGTAC 
CACGCCTTCG TGCGCCTCCC GGACCGCGAC TTCTCCTGCA GCCTCCGCCT GCGCGTCGGC 
CAGGCCTCGA TGATTGCCAG TCCCCCAGGA ACCCTCAAGC CGTCTGATTG GGTCATTTTG 
AACTGCTCCT TCAGTCGTCC TGACCGCCCA GTCTCTGTGC ACTGGTTCCA GGGCCAAAGC 
CGAGTGCCCG TCCACAATTC ACCCCGTCAT TATCTAGCTG AAAGTTTCCT CTTACTGCCC 
CAAGTCAGCC CACTGGATTC CGGGACCTGG GGCTGTGTCC TCACCTACAG AGATGGCTTC 
AATGTCTCCA TCACGTACAA CCTCAAGGTT CAGGGTCTGG AACCTGTAGC CCCTTTGACA 
GTGTACGCTG CTGAAGGTTC TAGGGTGGAG CTGCCCTGTC ACTTGCCTCC CGTTGTGGGG 
ACCCCTTCTT TGCTCATTGC CAAGTGGACT CCTCCTGGGG GAGGTCCTGA GCTCCCGGTG 
ACTGGAAAGA GTGGCAATTT TACCCTTCAA CTTGAGAATG TGGGTCGGGC ACAGGCTGGG 
ACCTACACCT GCAGCATCCA TCTGCAGGGG CGGCAGCTCA GTGCGGCTGT GACGTTGGCA 
GTCATCACAG TGACTCCTAA ATCCTTCGGG TTACCTGGCT CCCCGCAGAA GCTGTTATGT 
GAGGTAGTCC CGGCATCTGG AGAAGGAAGA TTTGTGTGGC GCCCCCTCAG CGATCTGTCC 
AGGAGTTCCC TGGGCCCTGT GCTGGAGTTG CAGGAGGCCA AGCTTCTGGC TGAGCAATGG 
CAGTGTCAGC TGTATGAGGG CCAGAAACTT CTTGGAGCAA CAGTGTACAC CGCAGAGTCT 
AGCTCAGGCG CCTGGAGTGC TAAGAGAATC TCAGGTGACC TTAAAGGAGG CCATCTCTTC 
CTCTCTCTCA TCCTTGGTGC CCTTGCCTTG TTCCTCTTGG TGACCGGGGC CTTTGGCTTT 
CACCTGTGGA GAAGACAGTT GCTACGGAGA AGATTTTCTG CCTTAGAGCA TGGGATTCGC 
CCACCTCCGG TTCAGAGTAA GATAGAGGAG CTGGAGCGAG AACCGGAGAC CGAGATGGAA 
CCAGAGACAG AGCCCGATCC GGAGCCTCAG CCGGAGCCCG AGCTGGAACC AGAGTCCAGG 
CAGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006237410.1
CDS	603..1931
Translation	MPSTRRHPPHRYTVLSVAPGGLRSGRQPLLSHVQLEKRGPQRGDFSLWLRPATRKDAGEYHAFVRLPDRDFSCSLRLRVGQASMIASPPGTLKPSDWVILNCSFSRPDRPVSVHWFQGQSRVPVHNSPRHYLAESFLLLPQVSPLDSGTWGCVLTYRDGFNVSITYNLKVQGLEPVAPLTVYAAEGSRVELPCHLPPVVGTPSLLIAKWTPPGGGPELPVTGKSGNFTLQLENVGRAQAGTYTCSIHLQGRQLSAAVTLAVITVTPKSFGLPGSPQKLLCEVVPASGEGRFVWRPLSDLSRSSLGPVLELQEAKLLAEQWQCQLYEGQKLLGATVYTAESSSGAWSAKRISGDLKGGHLFLSLILGALALFLLVTGAFGFHLWRRQLLRRRFSALEHGIRPPPVQSKIEELEREPETEMEPETEPDPEPQPEPELEPESRQL

Target ORF information:

RefSeq Version	XM_006237348.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lymphocyte activating 3 (Lag3), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006237348.3

ORF Insert Sequence:

ATGCCCTCGA CTAGGAGACA CCCACCCCAT CGCTACACGG TGCTGAGTGT GGCTCCAGGA 
GGCCTGCGCA GCGGGAGGCA GCCCCTGCTA TCCCACGTGC AGCTGGAGAA GCGTGGCCCC 
CAGCGCGGGG ACTTCTCTCT GTGGTTGCGC CCAGCTACGC GCAAAGATGC GGGCGAGTAC 
CACGCCTTCG TGCGCCTCCC GGACCGCGAC TTCTCCTGCA GCCTCCGCCT GCGCGTCGGC 
CAGGCCTCGA TGATTGCCAG TCCCCCAGGA ACCCTCAAGC CGTCTGATTG GGTCATTTTG 
AACTGCTCCT TCAGTCGTCC TGACCGCCCA GTCTCTGTGC ACTGGTTCCA GGGCCAAAGC 
CGAGTGCCCG TCCACAATTC ACCCCGTCAT TATCTAGCTG AAAGTTTCCT CTTACTGCCC 
CAAGTCAGCC CACTGGATTC CGGGACCTGG GGCTGTGTCC TCACCTACAG AGATGGCTTC 
AATGTCTCCA TCACGTACAA CCTCAAGGTT CAGGGTCTGG AACCTGTAGC CCCTTTGACA 
GTGTACGCTG CTGAAGGTTC TAGGGTGGAG CTGCCCTGTC ACTTGCCTCC CGTTGTGGGG 
ACCCCTTCTT TGCTCATTGC CAAGTGGACT CCTCCTGGGG GAGGTCCTGA GCTCCCGGTG 
ACTGGAAAGA GTGGCAATTT TACCCTTCAA CTTGAGAATG TGGGTCGGGC ACAGGCTGGG 
ACCTACACCT GCAGCATCCA TCTGCAGGGG CGGCAGCTCA GTGCGGCTGT GACGTTGGCA 
GTCATCACAG TGACTCCTAA ATCCTTCGGG TTACCTGGCT CCCCGCAGAA GCTGTTATGT 
GAGGTAGTCC CGGCATCTGG AGAAGGAAGA TTTGTGTGGC GCCCCCTCAG CGATCTGTCC 
AGGAGTTCCC TGGGCCCTGT GCTGGAGTTG CAGGAGGCCA AGCTTCTGGC TGAGCAATGG 
CAGTGTCAGC TGTATGAGGG CCAGAAACTT CTTGGAGCAA CAGTGTACAC CGCAGAGTCT 
AGCTCAGGCG CCTGGAGTGC TAAGAGAATC TCAGGTGACC TTAAAGGAGG CCATCTCTTC 
CTCTCTCTCA TCCTTGGTGC CCTTGCCTTG TTCCTCTTGG TGACCGGGGC CTTTGGCTTT 
CACCTGTGGA GAAGACAGTT GCTACGGAGA AGATTTTCTG CCTTAGAGCA TGGGATTCGC 
CCACCTCCGG TTCAGAGTAA GATAGAGGAG CTGGAGCGAG AACCGGAGAC CGAGATGGAA 
CCAGAGACAG AGCCCGATCC GGAGCCTCAG CCGGAGCCCG AGCTGGAACC AGAGTCCAGG 
CAGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lag3 ( XM_017592591.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017448080.1 Rattus norvegicus lymphocyte activating 3 (Lag3), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa27757
Clone ID Related Accession (Same CDS sequence)	XM_017592591.1 , XM_008763283.2
Accession Version	XM_017592591.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1362bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lymphocyte activation gene 3 protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTCACC TGGCAACATC GACCAGACAG GGAATGCCCT CGACTAGGAG ACACCCACCC 
CATCGCTACA CGGTGCTGAG TGTGGCTCCA GGAGGCCTGC GCAGCGGGAG GCAGCCCCTG 
CTATCCCACG TGCAGCTGGA GAAGCGTGGC CCCCAGCGCG GGGACTTCTC TCTGTGGTTG 
CGCCCAGCTA CGCGCAAAGA TGCGGGCGAG TACCACGCCT TCGTGCGCCT CCCGGACCGC 
GACTTCTCCT GCAGCCTCCG CCTGCGCGTC GGCCAGGCCT CGATGATTGC CAGTCCCCCA 
GGAACCCTCA AGCCGTCTGA TTGGGTCATT TTGAACTGCT CCTTCAGTCG TCCTGACCGC 
CCAGTCTCTG TGCACTGGTT CCAGGGCCAA AGCCGAGTGC CCGTCCACAA TTCACCCCGT 
CATTATCTAG CTGAAAGTTT CCTCTTACTG CCCCAAGTCA GCCCACTGGA TTCCGGGACC 
TGGGGCTGTG TCCTCACCTA CAGAGATGGC TTCAATGTCT CCATCACGTA CAACCTCAAG 
GTTCAGGGTC TGGAACCTGT AGCCCCTTTG ACAGTGTACG CTGCTGAAGG TTCTAGGGTG 
GAGCTGCCCT GTCACTTGCC TCCCGTTGTG GGGACCCCTT CTTTGCTCAT TGCCAAGTGG 
ACTCCTCCTG GGGGAGGTCC TGAGCTCCCG GTGACTGGAA AGAGTGGCAA TTTTACCCTT 
CAACTTGAGA ATGTGGGTCG GGCACAGGCT GGGACCTACA CCTGCAGCAT CCATCTGCAG 
GGGCGGCAGC TCAGTGCGGC TGTGACGTTG GCAGTCATCA CAGTGACTCC TAAATCCTTC 
GGGTTACCTG GCTCCCCGCA GAAGCTGTTA TGTGAGGTAG TCCCGGCATC TGGAGAAGGA 
AGATTTGTGT GGCGCCCCCT CAGCGATCTG TCCAGGAGTT CCCTGGGCCC TGTGCTGGAG 
TTGCAGGAGG CCAAGCTTCT GGCTGAGCAA TGGCAGTGTC AGCTGTATGA GGGCCAGAAA 
CTTCTTGGAG CAACAGTGTA CACCGCAGAG TCTAGCTCAG GCGCCTGGAG TGCTAAGAGA 
ATCTCAGGTG ACCTTAAAGG AGGCCATCTC TTCCTCTCTC TCATCCTTGG TGCCCTTGCC 
TTGTTCCTCT TGGTGACCGG GGCCTTTGGC TTTCACCTGT GGAGAAGACA GTTGCTACGG 
AGAAGATTTT CTGCCTTAGA GCATGGGATT CGCCCACCTC CGGTTCAGAG TAAGATAGAG 
GAGCTGGAGC GAGAACCGGA GACCGAGATG GAACCAGAGA CAGAGCCCGA TCCGGAGCCT 
CAGCCGGAGC CCGAGCTGGA ACCAGAGTCC AGGCAGCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017448080.1
CDS	334..1695
Translation	MGHLATSTRQGMPSTRRHPPHRYTVLSVAPGGLRSGRQPLLSHVQLEKRGPQRGDFSLWLRPATRKDAGEYHAFVRLPDRDFSCSLRLRVGQASMIASPPGTLKPSDWVILNCSFSRPDRPVSVHWFQGQSRVPVHNSPRHYLAESFLLLPQVSPLDSGTWGCVLTYRDGFNVSITYNLKVQGLEPVAPLTVYAAEGSRVELPCHLPPVVGTPSLLIAKWTPPGGGPELPVTGKSGNFTLQLENVGRAQAGTYTCSIHLQGRQLSAAVTLAVITVTPKSFGLPGSPQKLLCEVVPASGEGRFVWRPLSDLSRSSLGPVLELQEAKLLAEQWQCQLYEGQKLLGATVYTAESSSGAWSAKRISGDLKGGHLFLSLILGALALFLLVTGAFGFHLWRRQLLRRRFSALEHGIRPPPVQSKIEELEREPETEMEPETEPDPEPQPEPELEPESRQL

Target ORF information:

RefSeq Version	XM_017592591.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lymphocyte activating 3 (Lag3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017592591.1

ORF Insert Sequence:

ATGGGTCACC TGGCAACATC GACCAGACAG GGAATGCCCT CGACTAGGAG ACACCCACCC 
CATCGCTACA CGGTGCTGAG TGTGGCTCCA GGAGGCCTGC GCAGCGGGAG GCAGCCCCTG 
CTATCCCACG TGCAGCTGGA GAAGCGTGGC CCCCAGCGCG GGGACTTCTC TCTGTGGTTG 
CGCCCAGCTA CGCGCAAAGA TGCGGGCGAG TACCACGCCT TCGTGCGCCT CCCGGACCGC 
GACTTCTCCT GCAGCCTCCG CCTGCGCGTC GGCCAGGCCT CGATGATTGC CAGTCCCCCA 
GGAACCCTCA AGCCGTCTGA TTGGGTCATT TTGAACTGCT CCTTCAGTCG TCCTGACCGC 
CCAGTCTCTG TGCACTGGTT CCAGGGCCAA AGCCGAGTGC CCGTCCACAA TTCACCCCGT 
CATTATCTAG CTGAAAGTTT CCTCTTACTG CCCCAAGTCA GCCCACTGGA TTCCGGGACC 
TGGGGCTGTG TCCTCACCTA CAGAGATGGC TTCAATGTCT CCATCACGTA CAACCTCAAG 
GTTCAGGGTC TGGAACCTGT AGCCCCTTTG ACAGTGTACG CTGCTGAAGG TTCTAGGGTG 
GAGCTGCCCT GTCACTTGCC TCCCGTTGTG GGGACCCCTT CTTTGCTCAT TGCCAAGTGG 
ACTCCTCCTG GGGGAGGTCC TGAGCTCCCG GTGACTGGAA AGAGTGGCAA TTTTACCCTT 
CAACTTGAGA ATGTGGGTCG GGCACAGGCT GGGACCTACA CCTGCAGCAT CCATCTGCAG 
GGGCGGCAGC TCAGTGCGGC TGTGACGTTG GCAGTCATCA CAGTGACTCC TAAATCCTTC 
GGGTTACCTG GCTCCCCGCA GAAGCTGTTA TGTGAGGTAG TCCCGGCATC TGGAGAAGGA 
AGATTTGTGT GGCGCCCCCT CAGCGATCTG TCCAGGAGTT CCCTGGGCCC TGTGCTGGAG 
TTGCAGGAGG CCAAGCTTCT GGCTGAGCAA TGGCAGTGTC AGCTGTATGA GGGCCAGAAA 
CTTCTTGGAG CAACAGTGTA CACCGCAGAG TCTAGCTCAG GCGCCTGGAG TGCTAAGAGA 
ATCTCAGGTG ACCTTAAAGG AGGCCATCTC TTCCTCTCTC TCATCCTTGG TGCCCTTGCC 
TTGTTCCTCT TGGTGACCGG GGCCTTTGGC TTTCACCTGT GGAGAAGACA GTTGCTACGG 
AGAAGATTTT CTGCCTTAGA GCATGGGATT CGCCCACCTC CGGTTCAGAG TAAGATAGAG 
GAGCTGGAGC GAGAACCGGA GACCGAGATG GAACCAGAGA CAGAGCCCGA TCCGGAGCCT 
CAGCCGGAGC CCGAGCTGGA ACCAGAGTCC AGGCAGCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lag3 ( XM_008763283.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008761505.1 Rattus norvegicus lymphocyte activating 3 (Lag3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa27757
Clone ID Related Accession (Same CDS sequence)	XM_017592591.1 , XM_008763283.2
Accession Version	XM_008763283.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1362bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	lymphocyte activation gene 3 protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008763283.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTCACC TGGCAACATC GACCAGACAG GGAATGCCCT CGACTAGGAG ACACCCACCC 
CATCGCTACA CGGTGCTGAG TGTGGCTCCA GGAGGCCTGC GCAGCGGGAG GCAGCCCCTG 
CTATCCCACG TGCAGCTGGA GAAGCGTGGC CCCCAGCGCG GGGACTTCTC TCTGTGGTTG 
CGCCCAGCTA CGCGCAAAGA TGCGGGCGAG TACCACGCCT TCGTGCGCCT CCCGGACCGC 
GACTTCTCCT GCAGCCTCCG CCTGCGCGTC GGCCAGGCCT CGATGATTGC CAGTCCCCCA 
GGAACCCTCA AGCCGTCTGA TTGGGTCATT TTGAACTGCT CCTTCAGTCG TCCTGACCGC 
CCAGTCTCTG TGCACTGGTT CCAGGGCCAA AGCCGAGTGC CCGTCCACAA TTCACCCCGT 
CATTATCTAG CTGAAAGTTT CCTCTTACTG CCCCAAGTCA GCCCACTGGA TTCCGGGACC 
TGGGGCTGTG TCCTCACCTA CAGAGATGGC TTCAATGTCT CCATCACGTA CAACCTCAAG 
GTTCAGGGTC TGGAACCTGT AGCCCCTTTG ACAGTGTACG CTGCTGAAGG TTCTAGGGTG 
GAGCTGCCCT GTCACTTGCC TCCCGTTGTG GGGACCCCTT CTTTGCTCAT TGCCAAGTGG 
ACTCCTCCTG GGGGAGGTCC TGAGCTCCCG GTGACTGGAA AGAGTGGCAA TTTTACCCTT 
CAACTTGAGA ATGTGGGTCG GGCACAGGCT GGGACCTACA CCTGCAGCAT CCATCTGCAG 
GGGCGGCAGC TCAGTGCGGC TGTGACGTTG GCAGTCATCA CAGTGACTCC TAAATCCTTC 
GGGTTACCTG GCTCCCCGCA GAAGCTGTTA TGTGAGGTAG TCCCGGCATC TGGAGAAGGA 
AGATTTGTGT GGCGCCCCCT CAGCGATCTG TCCAGGAGTT CCCTGGGCCC TGTGCTGGAG 
TTGCAGGAGG CCAAGCTTCT GGCTGAGCAA TGGCAGTGTC AGCTGTATGA GGGCCAGAAA 
CTTCTTGGAG CAACAGTGTA CACCGCAGAG TCTAGCTCAG GCGCCTGGAG TGCTAAGAGA 
ATCTCAGGTG ACCTTAAAGG AGGCCATCTC TTCCTCTCTC TCATCCTTGG TGCCCTTGCC 
TTGTTCCTCT TGGTGACCGG GGCCTTTGGC TTTCACCTGT GGAGAAGACA GTTGCTACGG 
AGAAGATTTT CTGCCTTAGA GCATGGGATT CGCCCACCTC CGGTTCAGAG TAAGATAGAG 
GAGCTGGAGC GAGAACCGGA GACCGAGATG GAACCAGAGA CAGAGCCCGA TCCGGAGCCT 
CAGCCGGAGC CCGAGCTGGA ACCAGAGTCC AGGCAGCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008761505.1
CDS	92..1453
Translation	MGHLATSTRQGMPSTRRHPPHRYTVLSVAPGGLRSGRQPLLSHVQLEKRGPQRGDFSLWLRPATRKDAGEYHAFVRLPDRDFSCSLRLRVGQASMIASPPGTLKPSDWVILNCSFSRPDRPVSVHWFQGQSRVPVHNSPRHYLAESFLLLPQVSPLDSGTWGCVLTYRDGFNVSITYNLKVQGLEPVAPLTVYAAEGSRVELPCHLPPVVGTPSLLIAKWTPPGGGPELPVTGKSGNFTLQLENVGRAQAGTYTCSIHLQGRQLSAAVTLAVITVTPKSFGLPGSPQKLLCEVVPASGEGRFVWRPLSDLSRSSLGPVLELQEAKLLAEQWQCQLYEGQKLLGATVYTAESSSGAWSAKRISGDLKGGHLFLSLILGALALFLLVTGAFGFHLWRRQLLRRRFSALEHGIRPPPVQSKIEELEREPETEMEPETEPDPEPQPEPELEPESRQL

Target ORF information:

RefSeq Version	XM_008763283.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lymphocyte activating 3 (Lag3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008763283.2

ORF Insert Sequence:

ATGGGTCACC TGGCAACATC GACCAGACAG GGAATGCCCT CGACTAGGAG ACACCCACCC 
CATCGCTACA CGGTGCTGAG TGTGGCTCCA GGAGGCCTGC GCAGCGGGAG GCAGCCCCTG 
CTATCCCACG TGCAGCTGGA GAAGCGTGGC CCCCAGCGCG GGGACTTCTC TCTGTGGTTG 
CGCCCAGCTA CGCGCAAAGA TGCGGGCGAG TACCACGCCT TCGTGCGCCT CCCGGACCGC 
GACTTCTCCT GCAGCCTCCG CCTGCGCGTC GGCCAGGCCT CGATGATTGC CAGTCCCCCA 
GGAACCCTCA AGCCGTCTGA TTGGGTCATT TTGAACTGCT CCTTCAGTCG TCCTGACCGC 
CCAGTCTCTG TGCACTGGTT CCAGGGCCAA AGCCGAGTGC CCGTCCACAA TTCACCCCGT 
CATTATCTAG CTGAAAGTTT CCTCTTACTG CCCCAAGTCA GCCCACTGGA TTCCGGGACC 
TGGGGCTGTG TCCTCACCTA CAGAGATGGC TTCAATGTCT CCATCACGTA CAACCTCAAG 
GTTCAGGGTC TGGAACCTGT AGCCCCTTTG ACAGTGTACG CTGCTGAAGG TTCTAGGGTG 
GAGCTGCCCT GTCACTTGCC TCCCGTTGTG GGGACCCCTT CTTTGCTCAT TGCCAAGTGG 
ACTCCTCCTG GGGGAGGTCC TGAGCTCCCG GTGACTGGAA AGAGTGGCAA TTTTACCCTT 
CAACTTGAGA ATGTGGGTCG GGCACAGGCT GGGACCTACA CCTGCAGCAT CCATCTGCAG 
GGGCGGCAGC TCAGTGCGGC TGTGACGTTG GCAGTCATCA CAGTGACTCC TAAATCCTTC 
GGGTTACCTG GCTCCCCGCA GAAGCTGTTA TGTGAGGTAG TCCCGGCATC TGGAGAAGGA 
AGATTTGTGT GGCGCCCCCT CAGCGATCTG TCCAGGAGTT CCCTGGGCCC TGTGCTGGAG 
TTGCAGGAGG CCAAGCTTCT GGCTGAGCAA TGGCAGTGTC AGCTGTATGA GGGCCAGAAA 
CTTCTTGGAG CAACAGTGTA CACCGCAGAG TCTAGCTCAG GCGCCTGGAG TGCTAAGAGA 
ATCTCAGGTG ACCTTAAAGG AGGCCATCTC TTCCTCTCTC TCATCCTTGG TGCCCTTGCC 
TTGTTCCTCT TGGTGACCGG GGCCTTTGGC TTTCACCTGT GGAGAAGACA GTTGCTACGG 
AGAAGATTTT CTGCCTTAGA GCATGGGATT CGCCCACCTC CGGTTCAGAG TAAGATAGAG 
GAGCTGGAGC GAGAACCGGA GACCGAGATG GAACCAGAGA CAGAGCCCGA TCCGGAGCCT 
CAGCCGGAGC CCGAGCTGGA ACCAGAGTCC AGGCAGCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LAG-3 regulates plasmacytoid dendritic cell homeostasis.
Journal of immunology (Baltimore, Md. : 1950)182(4)1885-91(2009 Feb)
Workman CJ,Wang Y,El Kasmi KC,Pardoll DM,Murray PJ,Drake CG,Vignali DA

Depletion of LAG-3 positive cells in cardiac allograft reveals their role in rejection and tolerance.
Transplantation84(11)1500-6(2007 Dec)
Haudebourg T,Dugast AS,Coulon F,Usal C,Triebel F,Vanhove B

A soluble form of lymphocyte activation gene-3 (IMP321) induces activation of a large range of human effector cytotoxic cells.
Journal of immunology (Baltimore, Md. : 1950)179(6)4202-11(2007 Sep)
Brignone C,Grygar C,Marcu M,Sch?kel K,Triebel F

Role of LAG-3 in regulatory T cells.
Immunity21(4)503-13(2004 Oct)
Huang CT,Workman CJ,Flies D,Pan X,Marson AL,Zhou G,Hipkiss EL,Ravi S,Kowalski J,Levitsky HI,Powell JD,Pardoll DM,Drake CG,Vignali DA

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Lag3 cDNA ORF clone, Rattus norvegicus(Norway rat)

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gRNAs

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ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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