Sec13 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sec13
Entrez Gene ID	297522
Full Name	SEC13 homolog, nuclear pore and COPII coat complex component
Synonyms	Sec13l1
General protein information	Preferred Names SEC13 homolog, nuclear pore and COPII coat complex component Names protein SEC13 homolog GATOR complex protein SEC13 SEC13 homolog, nuclear pore and COPII coating complex component SEC13-like protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q42

mRNA and Protein(s)

mRNA	Protein	Name
NM_001006978.1	NP_001006979.1	protein SEC13 homolog

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SEC13	XP_516277.3
Bos taurus (cattle)	SEC13	NP_001069033.1
Rattus norvegicus (Norway rat)	Sec13	NP_001006979.1
Danio rerio (zebrafish)	sec13	NP_998500.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003183	XP_312881.4
Caenorhabditis elegans (roundworm)	npp-20	NP_500086.1
Eremothecium gossypii	AGOS_ACR199C	NP_983601.1
Arabidopsis thaliana (thale cress)	AT3G01340	NP_186783.1
Mus musculus (house mouse)	Sec13	NP_077168.2
Gallus gallus (chicken)	SEC13	NP_001264770.1
Drosophila melanogaster (fruit fly)	sec13	NP_651977.1
Arabidopsis thaliana (thale cress)	AT2G30050	NP_180566.1
Xenopus tropicalis (tropical clawed frog)	sec13	NP_988967.1
Homo sapiens (human)	SEC13	NP_001129498.1
	SEC13	XP_001089862.2
Saccharomyces cerevisiae (baker's yeast)	SEC13	NP_013309.1
Kluyveromyces lactis	KLLA0C16643g	XP_452944.1
Schizosaccharomyces pombe (fission yeast)	sec13	NP_596692.1
Magnaporthe oryzae (rice blast fungus)	MGG_14666	XP_003718375.1
Neurospora crassa	NCU04063	XP_957678.2
Oryza sativa (rice)	Os02g0135800	NP_001045820.1
Canis lupus familiaris (dog)	SEC13	XP_850437.1

Gene Ontology
Bibliography

Related articles in PubMed

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.
Wolfson RL, Chantranupong L, Wyant GA, Gu X, Orozco JM, Shen K, Condon KJ, Petri S, Kedir J, Scaria SM, Abu-Remaileh M, Frankel WN, Sabatini DM
Nature543(7645)438-442(2017 03)

Systematic Protein-Protein Interaction Analysis Reveals Intersubcomplex Contacts in the Nuclear Pore Complex.
Apelt L, Knockenhauer KE, Leksa NC, Benlasfer N, Schwartz TU, Stelzl U
Molecular & cellular proteomics : MCP15(8)2594-606(2016 08)

SEC16A is a RAB10 effector required for insulin-stimulated GLUT4 trafficking in adipocytes.
Bruno J, Brumfield A, Chaudhary N, Iaea D, McGraw TE
The Journal of cell biology214(1)61-76(2016 Jul)

Regulation of mRNA trafficking by nuclear pore complexes.
Bonnet A, Palancade B
Genes5(3)767-91(2014 Sep)

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.
Bar-Peled L, Chantranupong L, Cherniack AD, Chen WW, Ottina KA, Grabiner BC, Spear ED, Carter SL, Meyerson M, Sabatini DM
Science (New York, N.Y.)340(6136)1100-6(2013 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Sec13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sec13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10923	NM_001006978.1 Latest version!	Rattus norvegicus SEC13 homolog, nuclear pore and COPII coat complex component (Sec13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sec13 ( NM_001006978.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001006979.1 Rattus norvegicus SEC13 homolog, nuclear pore and COPII coat complex component (Sec13), mRNA.

Price & Availability↑

CloneID	ORa10923
Clone ID Related Accession (Same CDS sequence)	NM_001006978.1
Accession Version	NM_001006978.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 969bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Rattus norvegicus(Norway rat)
Product	protein SEC13 homolog
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC084705.1. On Nov 22, 2004 this sequence version replaced XM_216257.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC084705.1, CF110576.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906349, SAMN01906353 [ECO:0000348] ##Evidence-Data-END##

ATGGTGTCAG TAATTAACAC TGTGGATACC TCTCATGAGG ACATGATTCA TGATGCGCAG 
ATGGACTATT ATGGCACCCG CCTAGCAACC TGCTCCTCAG ATAGGTCTGT CAAAATTTTT 
GATGTGCGAA ATGGAGGGCA GATCCTCATC GCAGACCTCA GAGGACATGA GGGGCCAGTG 
TGGCAGGTGG CCTGGGCTCA CCCCATGTAT GGCAATATCC TGGCTTCCTG TTCCTATGAC 
CGGAAAGTCA TTATCTGGAA GGAGGAAAAT GGCACTTGGG AAAAGACCCA TGAGCACTCA 
GGACATGACT CCTCAGTGAA CTCTGTTTGC TGGGCCCCTC ATGACTATGG CCTGATCCTG 
GCCTGTGGGA GTTCAGATGG TGCCATCTCG CTGCTGACTT ATACAGGGGA AGGCCAGTGG 
GAAGTGAAGA AGATTAACAA TGCTCACACG ATTGGCTGTA ATGCTGTCAG TTGGGCCCCA 
GCTGTTGTGC CTGGAAGCCT TATAGACCAA CCATCCGGAC AGAAACCCAA TTACATCAAG 
AAGTTTGCAT CAGGTGGCTG TGACAATCTC ATCAAGTTGT GGAGGGAAGA GGAGGATGGC 
CAGTGGAAGG AGGAGCAAAA GCTAGAGGCA CACAGTGACT GGGTTCGAGA CGTTGCCTGG 
GCCCCCTCCA TTGGCTTGCC CACCAGCACC ATTGCCAGCT GCTCTCAGGA TGGGCGAGTG 
TTTATTTGGA CTTGTGATGA CGCCTCAGGC AATATGTGGT CACCTAAACT CCTACACAAG 
TTCAATGATG TCGTGTGGCA CGTGAGCTGG TCCATCACAG CAAATATCCT GGCTGTGTCA 
GGTGGAGACA ATAAGGTGAC CCTGTGGAAA GAGTCGGTGG ATGGACAGTG GGTGTGCATC 
AGTGATGTCA ACAAGGGCCA GGGTTCTGTG TCAGCCTCCA TCACAGAGGG CCAACAGAAT 
GAGCAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001006979.1
CDS	33..1001
Translation	MVSVINTVDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWKEENGTWEKTHEHSGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDQPSGQKPNYIKKFASGGCDNLIKLWREEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASGNMWSPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASITEGQQNEQ

Target ORF information:

RefSeq Version	NM_001006978.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus SEC13 homolog, nuclear pore and COPII coat complex component (Sec13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001006978.1

ORF Insert Sequence:

ATGGTGTCAG TAATTAACAC TGTGGATACC TCTCATGAGG ACATGATTCA TGATGCGCAG 
ATGGACTATT ATGGCACCCG CCTAGCAACC TGCTCCTCAG ATAGGTCTGT CAAAATTTTT 
GATGTGCGAA ATGGAGGGCA GATCCTCATC GCAGACCTCA GAGGACATGA GGGGCCAGTG 
TGGCAGGTGG CCTGGGCTCA CCCCATGTAT GGCAATATCC TGGCTTCCTG TTCCTATGAC 
CGGAAAGTCA TTATCTGGAA GGAGGAAAAT GGCACTTGGG AAAAGACCCA TGAGCACTCA 
GGACATGACT CCTCAGTGAA CTCTGTTTGC TGGGCCCCTC ATGACTATGG CCTGATCCTG 
GCCTGTGGGA GTTCAGATGG TGCCATCTCG CTGCTGACTT ATACAGGGGA AGGCCAGTGG 
GAAGTGAAGA AGATTAACAA TGCTCACACG ATTGGCTGTA ATGCTGTCAG TTGGGCCCCA 
GCTGTTGTGC CTGGAAGCCT TATAGACCAA CCATCCGGAC AGAAACCCAA TTACATCAAG 
AAGTTTGCAT CAGGTGGCTG TGACAATCTC ATCAAGTTGT GGAGGGAAGA GGAGGATGGC 
CAGTGGAAGG AGGAGCAAAA GCTAGAGGCA CACAGTGACT GGGTTCGAGA CGTTGCCTGG 
GCCCCCTCCA TTGGCTTGCC CACCAGCACC ATTGCCAGCT GCTCTCAGGA TGGGCGAGTG 
TTTATTTGGA CTTGTGATGA CGCCTCAGGC AATATGTGGT CACCTAAACT CCTACACAAG 
TTCAATGATG TCGTGTGGCA CGTGAGCTGG TCCATCACAG CAAATATCCT GGCTGTGTCA 
GGTGGAGACA ATAAGGTGAC CCTGTGGAAA GAGTCGGTGG ATGGACAGTG GGTGTGCATC 
AGTGATGTCA ACAAGGGCCA GGGTTCTGTG TCAGCCTCCA TCACAGAGGG CCAACAGAAT 
GAGCAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.
Nature543(7645)438-442(2017 03)
Wolfson RL,Chantranupong L,Wyant GA,Gu X,Orozco JM,Shen K,Condon KJ,Petri S,Kedir J,Scaria SM,Abu-Remaileh M,Frankel WN,Sabatini DM

Systematic Protein-Protein Interaction Analysis Reveals Intersubcomplex Contacts in the Nuclear Pore Complex.
Molecular & cellular proteomics : MCP15(8)2594-606(2016 08)
Apelt L,Knockenhauer KE,Leksa NC,Benlasfer N,Schwartz TU,Stelzl U

SEC16A is a RAB10 effector required for insulin-stimulated GLUT4 trafficking in adipocytes.
The Journal of cell biology214(1)61-76(2016 Jul)
Bruno J,Brumfield A,Chaudhary N,Iaea D,McGraw TE

Regulation of mRNA trafficking by nuclear pore complexes.
Genes5(3)767-91(2014 Sep)
Bonnet A,Palancade B

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.
Science (New York, N.Y.)340(6136)1100-6(2013 May)
Bar-Peled L,Chantranupong L,Cherniack AD,Chen WW,Ottina KA,Grabiner BC,Spear ED,Carter SL,Meyerson M,Sabatini DM