Chchd6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Chchd6
Entrez Gene ID	297436
Full Name	coiled-coil-helix-coiled-coil-helix domain containing 6
General protein information	Preferred Names coiled-coil-helix-coiled-coil-helix domain containing 6 Names MICOS complex subunit Mic25 coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q34

mRNA and Protein(s)

mRNA	Protein	Name
NM_001106608.1	NP_001100078.1	MICOS complex subunit Mic25
XM_006236846.3	XP_006236908.1	MICOS complex subunit Mic25 isoform X1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	chchd6a	NP_001005584.1
Bos taurus (cattle)	CHCHD6	NP_001069870.1
Xenopus tropicalis (tropical clawed frog)	chchd6	XP_004914145.1
Homo sapiens (human)	CHCHD6	NP_115719.1
	CHCHD6	XP_001114416.1
Rattus norvegicus (Norway rat)	Chchd6	NP_001100078.1
Gallus gallus (chicken)	CHCHD6	XP_001233145.2
Pan troglodytes (chimpanzee)	CHCHD6	XP_001135815.1
Canis lupus familiaris (dog)	CHCHD6	XP_533716.4
Mus musculus (house mouse)	Chchd6	NP_079627.3

Gene Ontology
Bibliography

Related articles in PubMed

QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology.
Guarani V, McNeill EM, Paulo JA, Huttlin EL, Fr?hlich F, Gygi SP, Van Vactor D, Harper JW
eLife4(2015 May)

Detailed analysis of the human mitochondrial contact site complex indicate a hierarchy of subunits.
Ott C, Dorsch E, Fraunholz M, Straub S, Kozjak-Pavlovic V
PloS one10(3)e0120213(2015)

Mitofilin complexes: conserved organizers of mitochondrial membrane architecture.
Zerbes RM, van der Klei IJ, Veenhuis M, Pfanner N, van der Laan M, Bohnert M
Biological chemistry393(11)1247-61(2012 Nov)

CHCM1/CHCHD6, novel mitochondrial protein linked to regulation of mitofilin and mitochondrial cristae morphology.
An J, Shi J, He Q, Lui K, Liu Y, Huang Y, Sheikh MS
The Journal of biological chemistry287(10)7411-26(2012 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Chchd6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Chchd6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01780	NM_001106608.1 Latest version!	Rattus norvegicus coiled-coil-helix-coiled-coil-helix domain containing 6 (Chchd6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa27445	XM_006236846.3 Latest version!	Rattus norvegicus coiled-coil-helix-coiled-coil-helix domain containing 6 (Chchd6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Chchd6 ( NM_001106608.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100078.1 Rattus norvegicus coiled-coil-helix-coiled-coil-helix domain containing 6 (Chchd6), mRNA.

Price & Availability↑

CloneID	ORa01780
Clone ID Related Accession (Same CDS sequence)	NM_001106608.1
Accession Version	NM_001106608.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 786bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-17
Organism	Rattus norvegicus(Norway rat)
Product	MICOS complex subunit Mic25
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473957.1. On or before Oct 4, 2007 this sequence version replaced XM_001072660.1, XM_001072693.1, XM_216212.4. ##Evidence-Data-START## Transcript exon combination :: FQ219980.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGCAGCT CAGAGAGCGC CGAGGCCCGA AGGGTGTCCT TCGAGATGGA TGAGGAGGAG 
CGGGTCCGGG TGCTGCAGGG CATCCGGCTG TCCGAAAGTG TTGTGAACCG CATGAAGGAT 
TGCAGCCAGC CTTCAGCAGG GGAACAGCTG GCTCCTGGTC CTGGTCCTGA GTGCTCCGTT 
CCTGTGCCCA CTGTCCCTCA ACCAACCATT CCAGTGCTTA CTGTTCCTTC ACCCTCTGTA 
TGTGGGCCCG CAGAAGGCAC CTATAAAGCC CCTCAGGGAG ACTTTAAAGT GTCCAGGGCA 
GAGAATAGTG ATGGCCAGCA GTCCTCAGCA GTGAAGGAGG ATCTCAAGAA GTTCCAACAG 
GAGCAGCTGG CAGTCCAGGA TGAGCTGGTC AAGGTGGCAA GAAAGGAGAA AGAGGCAACT 
GAGAAGCACT TGAAGGCATC CCTGCCCAAG AAGAAGGCCA CCCACGAGCA GCAGCAGTCA 
GATCGCCTAA CCAGGGAACT GAAGAACAGA GAGGCCGAGC TCAGCCGCCG TGACACTTTC 
TACAAGGAGC AGCAGGAACG CATCCAAGAG AAGAATGCTG AGCTGTATAA ACTGTCTTCT 
CAACAATTCC ACGAGGCGGC TTCAAAAGCA GAGAGCACAA TAAAGCCCCG CAGAGTGGAG 
CCTGTATGCT CTGGCCTACA GGCCCAGATC CTCCGCTGCT ACCGTGACCA TCTGCATGAG 
GTACTTCTAT GCTCCGACCT GGCCAAGGCA TACCAGCACT GTGTGAGCAC CGCCCGCAAG 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100078.1
CDS	94..879
Translation	MGSSESAEARRVSFEMDEEERVRVLQGIRLSESVVNRMKDCSQPSAGEQLAPGPGPECSVPVPTVPQPTIPVLTVPSPSVCGPAEGTYKAPQGDFKVSRAENSDGQQSSAVKEDLKKFQQEQLAVQDELVKVARKEKEATEKHLKASLPKKKATHEQQQSDRLTRELKNREAELSRRDTFYKEQQERIQEKNAELYKLSSQQFHEAASKAESTIKPRRVEPVCSGLQAQILRCYRDHLHEVLLCSDLAKAYQHCVSTARKG

Target ORF information:

RefSeq Version	NM_001106608.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus coiled-coil-helix-coiled-coil-helix domain containing 6 (Chchd6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106608.1

ORF Insert Sequence:

ATGGGCAGCT CAGAGAGCGC CGAGGCCCGA AGGGTGTCCT TCGAGATGGA TGAGGAGGAG 
CGGGTCCGGG TGCTGCAGGG CATCCGGCTG TCCGAAAGTG TTGTGAACCG CATGAAGGAT 
TGCAGCCAGC CTTCAGCAGG GGAACAGCTG GCTCCTGGTC CTGGTCCTGA GTGCTCCGTT 
CCTGTGCCCA CTGTCCCTCA ACCAACCATT CCAGTGCTTA CTGTTCCTTC ACCCTCTGTA 
TGTGGGCCCG CAGAAGGCAC CTATAAAGCC CCTCAGGGAG ACTTTAAAGT GTCCAGGGCA 
GAGAATAGTG ATGGCCAGCA GTCCTCAGCA GTGAAGGAGG ATCTCAAGAA GTTCCAACAG 
GAGCAGCTGG CAGTCCAGGA TGAGCTGGTC AAGGTGGCAA GAAAGGAGAA AGAGGCAACT 
GAGAAGCACT TGAAGGCATC CCTGCCCAAG AAGAAGGCCA CCCACGAGCA GCAGCAGTCA 
GATCGCCTAA CCAGGGAACT GAAGAACAGA GAGGCCGAGC TCAGCCGCCG TGACACTTTC 
TACAAGGAGC AGCAGGAACG CATCCAAGAG AAGAATGCTG AGCTGTATAA ACTGTCTTCT 
CAACAATTCC ACGAGGCGGC TTCAAAAGCA GAGAGCACAA TAAAGCCCCG CAGAGTGGAG 
CCTGTATGCT CTGGCCTACA GGCCCAGATC CTCCGCTGCT ACCGTGACCA TCTGCATGAG 
GTACTTCTAT GCTCCGACCT GGCCAAGGCA TACCAGCACT GTGTGAGCAC CGCCCGCAAG 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Chchd6 ( XM_006236846.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006236908.1 Rattus norvegicus coiled-coil-helix-coiled-coil-helix domain containing 6 (Chchd6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa27445
Clone ID Related Accession (Same CDS sequence)	XM_006236846.3
Accession Version	XM_006236846.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	MICOS complex subunit Mic25 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006236846.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCAGCT CAGAGAGCGC CGAGGCCCGA AGGGTGTCCT TCGAGATGGA TGAGGAGGAG 
CGGGTCCGGG TGCTGCAGGG CATCCGGCTG TCCGAAAGTG TTGTGAACCG CATGAAGGAT 
TGCAGCCAGC CTTCAGCAGG GGAACAGCTG GCTCCTGGTC CTGGTCCTGA GTGCTCCGTT 
CCTGTGCCCA CTGTCCCTCA ACCAACCATT CCAGTGCTTA CTGTTCCTTC ACCCTCTGTA 
TGTGGGCCCG CAGAAGGCAC CTATAAAGCC CCTCAGGGAG ACTTTAAAGT GTCCAGGGCA 
GAGAATAGTG ATGGCCAGCA GTCCTCAGCA GTGAAGGAGG ATCTCAAGAA GTTCCAACAG 
GAGCAGCTGG CAGTCCAGGA TGAGCTGGTC AAGGTGGCAA GAAAGGAGAA AGAGGCAACT 
GAGAAGCACT TGAAGGCATC CCTGCCCAAG AAGAAGGCCA CCCACGAGCA GCAGCAGTCA 
GATCGCCTAA CCAGGGAACT GAAGAACAGA GAGGCCGAGC TCAGCCGCCG TGACACTTTC 
TACAAGGAGC AGCAGGAACG CATCCAAGAG AAGAATGCTG AGCTGTATAA ACTGTCTTCT 
CAACAATTCC ACGAGGCGGC TTCAAAAGCA GAGAGCACAA TAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006236908.1
CDS	104..751
Translation	MGSSESAEARRVSFEMDEEERVRVLQGIRLSESVVNRMKDCSQPSAGEQLAPGPGPECSVPVPTVPQPTIPVLTVPSPSVCGPAEGTYKAPQGDFKVSRAENSDGQQSSAVKEDLKKFQQEQLAVQDELVKVARKEKEATEKHLKASLPKKKATHEQQQSDRLTRELKNREAELSRRDTFYKEQQERIQEKNAELYKLSSQQFHEAASKAESTIK

Target ORF information:

RefSeq Version	XM_006236846.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus coiled-coil-helix-coiled-coil-helix domain containing 6 (Chchd6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006236846.3

ORF Insert Sequence:

ATGGGCAGCT CAGAGAGCGC CGAGGCCCGA AGGGTGTCCT TCGAGATGGA TGAGGAGGAG 
CGGGTCCGGG TGCTGCAGGG CATCCGGCTG TCCGAAAGTG TTGTGAACCG CATGAAGGAT 
TGCAGCCAGC CTTCAGCAGG GGAACAGCTG GCTCCTGGTC CTGGTCCTGA GTGCTCCGTT 
CCTGTGCCCA CTGTCCCTCA ACCAACCATT CCAGTGCTTA CTGTTCCTTC ACCCTCTGTA 
TGTGGGCCCG CAGAAGGCAC CTATAAAGCC CCTCAGGGAG ACTTTAAAGT GTCCAGGGCA 
GAGAATAGTG ATGGCCAGCA GTCCTCAGCA GTGAAGGAGG ATCTCAAGAA GTTCCAACAG 
GAGCAGCTGG CAGTCCAGGA TGAGCTGGTC AAGGTGGCAA GAAAGGAGAA AGAGGCAACT 
GAGAAGCACT TGAAGGCATC CCTGCCCAAG AAGAAGGCCA CCCACGAGCA GCAGCAGTCA 
GATCGCCTAA CCAGGGAACT GAAGAACAGA GAGGCCGAGC TCAGCCGCCG TGACACTTTC 
TACAAGGAGC AGCAGGAACG CATCCAAGAG AAGAATGCTG AGCTGTATAA ACTGTCTTCT 
CAACAATTCC ACGAGGCGGC TTCAAAAGCA GAGAGCACAA TAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology.
eLife4(2015 May)
Guarani V,McNeill EM,Paulo JA,Huttlin EL,Fr?hlich F,Gygi SP,Van Vactor D,Harper JW

Detailed analysis of the human mitochondrial contact site complex indicate a hierarchy of subunits.
PloS one10(3)e0120213(2015)
Ott C,Dorsch E,Fraunholz M,Straub S,Kozjak-Pavlovic V

Mitofilin complexes: conserved organizers of mitochondrial membrane architecture.
Biological chemistry393(11)1247-61(2012 Nov)
Zerbes RM,van der Klei IJ,Veenhuis M,Pfanner N,van der Laan M,Bohnert M

CHCM1/CHCHD6, novel mitochondrial protein linked to regulation of mitofilin and mitochondrial cristae morphology.
The Journal of biological chemistry287(10)7411-26(2012 Mar)
An J,Shi J,He Q,Lui K,Liu Y,Huang Y,Sheikh MS