Gsn cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gsn
Entrez Gene ID	296654
Full Name	gelsolin
General protein information	Preferred Names gelsolin Names gelsolin ADF actin-depolymerizing factor brevin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3p11
Summary	plays a role in phosphoinositide mediated disassembly of actin filaments in Sertoli cell adhesion complexes; may regulate sperm release and turnover of the blood-testis barrier [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001004080.1	NP_001004080.1	gelsolin precursor
XM_017591662.1	XP_017447151.1	gelsolin isoform X1
XM_006234040.2	XP_006234102.1	gelsolin isoform X2

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	gsn	NP_001016856.1
Rattus norvegicus (Norway rat)	Gsn	NP_001004080.1
	GSN	XP_001093567.1
Canis lupus familiaris (dog)	GSN	XP_005627064.1
Gallus gallus (chicken)	GSN	NP_990265.1
Homo sapiens (human)	GSN	NP_000168.1
Pan troglodytes (chimpanzee)	GSN	XP_001161890.1
Bos taurus (cattle)	GSN	NP_001106755.1
Danio rerio (zebrafish)	gsna	NP_001012312.1
Mus musculus (house mouse)	Gsn	NP_666232.2
Magnaporthe oryzae (rice blast fungus)	MGG_10059	XP_003717447.1

Gene Ontology
Bibliography

Related articles in PubMed

LINGO-1 Regulates Oligodendrocyte Differentiation through the Cytoplasmic Gelsolin Signaling Pathway.
Shao Z, Lee X, Huang G, Sheng G, Henderson CE, Louvard D, Sohn J, Pepinsky B, Mi S
The Journal of neuroscience : the official journal of the Society for Neuroscience37(12)3127-3137(2017 Mar)

Hypoxia Augments Increased HIF-1? and Reduced Survival Protein p-Akt in Gelsolin (GSN)-Dependent Cardiomyoblast Cell Apoptosis.
Yeh YL, Ting WJ, Shen CY, Hsu HH, Chung LC, Tu CC, Chang SH, Day CH, Tsai Y, Huang CY
Cell biochemistry and biophysics74(2)221-8(2016 Jun)

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Barallobre-Barreiro J, Oklu R, Lynch M, Fava M, Baig F, Yin X, Barwari T, Potier DN, Albadawi H, Jahangiri M, Porter KE, Watkins MT, Misra S, Stoughton J, Mayr M
Cardiovascular research110(3)419-30(2016 06)

Expression of Cytoplasmic Gelsolin in Rat Brain After Experimental Subarachnoid Hemorrhage.
Xie GB, Wang CX, Zhou CH, Li H, Zhang XS, Zhou XM, Zhang L, Hang CH, Zhou ML, Shi JX
Cellular and molecular neurobiology35(5)723-31(2015 Jul)

The Stress-Induced Atf3-Gelsolin Cascade Underlies Dendritic Spine Deficits in Neuronal Models of Tuberous Sclerosis Complex.
Nie D, Chen Z, Ebrahimi-Fakhari D, Di Nardo A, Julich K, Robson VK, Cheng YC, Woolf CJ, Heiman M, Sahin M
The Journal of neuroscience : the official journal of the Society for Neuroscience35(30)10762-72(2015 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Myelin loss and subsequent axon degeneration contributes to a variety of neurological diseases, such as multiple sclerosis (MS).
Title: LINGO-1 Regulates Oligodendrocyte Differentiation through the Cytoplasmic Gelsolin Signaling Pathway.

hypoxia or GSN overexpression induces HIF-1alpha expression and reduces the expression of survival markers p-Akt and Bcl-2 in H9c2 cardiomyoblast cells
Title: Hypoxia Augments Increased HIF-1? and Reduced Survival Protein p-Akt in Gelsolin (GSN)-Dependent Cardiomyoblast Cell Apoptosis.

These findings suggested a potential role of GSN in the pathophysiology of the brain at the early stage of subarachnoid hemorrhage.
Title: Expression of Cytoplasmic Gelsolin in Rat Brain After Experimental Subarachnoid Hemorrhage.

our data demonstrate that a cell-autonomous program consisting of a stress-induced Atf3-gelsolin cascade affects the change in dendritic spine morphology in models of tuberous sclerosis complex
Title: The Stress-Induced Atf3-Gelsolin Cascade Underlies Dendritic Spine Deficits in Neuronal Models of Tuberous Sclerosis Complex.

It was concluded that cytoskeletal effects of Cd in mesangial cells are partially mediated by Cd-dependent activation of CaMK-IIdelta, binding of CaMK-IIdelta and gelsolin to actin filaments, and cleavage of gelsolin.
Title: Involvement of CaMK-II? and gelsolin in Cd(2+) -dependent cytoskeletal effects in mesangial cells.

The following Gsn gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gsn cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa09945	NM_001004080.1 Latest version!	Rattus norvegicus gelsolin (Gsn), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$461.30 $659.00
ORa25768	XM_006234040.2 Latest version!	Rattus norvegicus gelsolin (Gsn), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
ORa25767	XM_017591662.1 Latest version!	Rattus norvegicus gelsolin (Gsn), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gsn ( NM_001004080.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001004080.1 Rattus norvegicus gelsolin (Gsn), mRNA.

Price & Availability↑

CloneID	ORa09945
Clone ID Related Accession (Same CDS sequence)	NM_001004080.1
Accession Version	NM_001004080.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2343bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	gelsolin precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079472.1. On Sep 3, 2004 this sequence version replaced XM_216043.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC079472.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMEA2689595 [ECO:0000348] ##Evidence-Data-END##

ATGGCTCCGT ATTGCTCCTC GCTGCGCTCT GCGCTGCTCG TCCTGGCGCT GTGCGCACTG 
TCGCCGTCCC ATGCAGCCAC CGCATCGCGG GGCAGGGCCC AAGAGAGGGC GCCCCAAAGT 
CGGGTGTCTG AGACGCGGCC CAGCACCATG GTGGTGGAGC ACCCCGAATT CCTGAAGGCA 
GGGAAGGAGC CTGGCCTGCA GATCTGGCGT GTGGAGAAGT TTGACCTGGT GCCTGTGCCC 
CCCAACCTCT ATGGAGACTT CTTCACGGGT GACGCCTATG TCATCCTAAA GACGGTGCAG 
CTGAGGAATG GGAATCTGCA GTATGACCTC CACTATTGGC TGGGCAACGA GTGCAGCCAG 
GACGAGAGCG GGGCTGCCGC CATCTTTACC GTGCAGCTGG ATGACTACCT GAATGGCCGG 
GCTGTACAGC ACCGTGAGGT TCAGGGCTTT GAGTCGTCCA CATTCCAAGG CTACTTCAAG 
TCTGGACTTA AGTACAAGAA AGGAGGCGTG GCATCTGGAT TCAAACACGT GGTACCCAAC 
GAGGTGGTGG TGCAGAGGCT CTTCCAGGTC AAGGGACGCC GTGTAGTCCG TGCCACTGAA 
GTACCTGTGT CCTGGGACAG TTTCAACAAC GGTGACTGCT TCATTCTGGA CCTGGGAAAT 
AATATCTATC AGTGGTGTGG CTCCGGCAGC AACAAGTTTG AAAGACTGAA GGCCACGCAG 
GTGTCCAAGG GCATCCGGGA CAACGAGAGG AGTGGACGCG CCCAAGTACA TGTGTCTGAA 
GAGGGTAGCG AGCCGGAAGC CATGCTCCAG GTGCTGGGCC CCAAGCCGGA TCTGCCTCAG 
GGCACCGAGG ACACAGCCAA GGAAGATGCT GCCAACCGAA GGCTGGCCAA GCTCTACAAG 
GTCTCCAACA GTGGAGGCAG CATGTCAGTC TCCCTCGTGG CTGACGAGAA CCCCTTCGCC 
CAGTCCGCCC TGAGATCCGA GGACTGTTTC ATCCTGGACC ACGGCAGAGA TGGGAAAATC 
TTTGTTTGGA AAGGCAAGCA GGCCAACATG GATGAGCGGA AGGCTGCCCT CAAAACAGCC 
TCTGACTTCA TCTCCAAGAT GCAGTACCCC AGGCAGACCC AGGTTTCAGT CCTCCCGGAG 
GGCGGCGAGA CTCCTCTCTT TAAGCAGTTC TTCAAGAACT GGCGGGACCC AGACCAGACA 
GACGGCCCTG GCCTGAGCTA CCTCTCCAGC CACATTGCCA ACGTGGAGCG CGTGCCTTTC 
GATGCTGCTA CACTGCACAC CTCCACTGCC ATGGCTGCCC AGCACGGCAT GGATGATGAC 
GGAACTGGCC AGAAACAGAT CTGGAGAATT GAAGGTTCCA ACAAGGTACT GGTGGACCCC 
GCCACATATG GCCAGTTCTA TGGAGGTGAC AGCTACATCA TTCTGTACAA CTACCGCCAT 
GGTGGCCGCC AGGGACAGAT CATCTACAAC TGGCAGGGTG CCCAGTCTAC CCAGGATGAG 
GTCGCTGCTT CAGCCATCCT GACTGCCCAG CTGGATGAGG AACTGGGAGG AACTCCTGTC 
CAGAGCCGAG TGGTCCAAGG CAAAGAGCCT GCACACCTCA TGAGCTTGTT TGGTGGGAAG 
CCCATGATCA TCTACAAGGG CGGCACCTCC CGAGATGGTG GGCAGACAAC CCCTGCCAGT 
ACCCGCCTCT TCCAAGTCCG GGCCAGCAGC TCTGGAGCCA CCAGGGCTGT TGAGGTAATG 
CCTAAGGCTG GCGCTCTCAA CTCCAATGAT GCCTTTGTGC TGAAAACCCC CTCCGCCGCC 
TACCTGTGGG TGGGTACAGG AGCCAGTGAT GCGGAGAAGA CCGGCGCCCT GGAGCTGCTG 
AAGGTGCTGA GGGCCCAGCA CGTGCAGGTG GAGGAAGGCA GTGAACCAGA TGGCTTCTGG 
GAGGCTCTGG GCGGGAAGAC TGCCTACCGC ACATCCCCCA GGCTTAAGGA CAAGAAGATG 
GATGCTCATC CTCCTCGCCT CTTCGCCTGC TCCAACAGGA TCGGGCGCTT TGTGATCGAA 
GAGGTTCCTG GCGAGCTTAT GCAGGAAGAC CTGGCTACTG ATGACGTCAT GCTCCTGGAC 
ACCTGGGACC AGGTCTTTGT CTGGGTTGGA AAGGACTCTC AGGAAGAGGA AAAGACAGAA 
GCCTTGACCT CTGCTAAGCG GTACATCGAG ACGGACCCAG CGAATCGGGA CAGGCGGACC 
CCCATCACTG TCGTTAGGCA AGGCTTTGAG CCTCCTTCCT TTGTGGGCTG GTTCCTCGGC 
TGGGATGATG ACTACTGGTC GGTGGATCCC TTGGACCGGG CCTTGGCTGA GCTGGCTGCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004080.1
CDS	11..2353
Translation	MAPYCSSLRSALLVLALCALSPSHAATASRGRAQERAPQSRVSETRPSTMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFQGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSGSNKFERLKATQVSKGIRDNERSGRAQVHVSEEGSEPEAMLQVLGPKPDLPQGTEDTAKEDAANRRLAKLYKVSNSGGSMSVSLVADENPFAQSALRSEDCFILDHGRDGKIFVWKGKQANMDERKAALKTASDFISKMQYPRQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGPGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVLVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSRDGGQTTPASTRLFQVRASSSGATRAVEVMPKAGALNSNDAFVLKTPSAAYLWVGTGASDAEKTGALELLKVLRAQHVQVEEGSEPDGFWEALGGKTAYRTSPRLKDKKMDAHPPRLFACSNRIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVRQGFEPPSFVGWFLGWDDDYWSVDPLDRALAELAA

Target ORF information:

RefSeq Version	NM_001004080.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus gelsolin (Gsn), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004080.1

ORF Insert Sequence:

ATGGCTCCGT ATTGCTCCTC GCTGCGCTCT GCGCTGCTCG TCCTGGCGCT GTGCGCACTG 
TCGCCGTCCC ATGCAGCCAC CGCATCGCGG GGCAGGGCCC AAGAGAGGGC GCCCCAAAGT 
CGGGTGTCTG AGACGCGGCC CAGCACCATG GTGGTGGAGC ACCCCGAATT CCTGAAGGCA 
GGGAAGGAGC CTGGCCTGCA GATCTGGCGT GTGGAGAAGT TTGACCTGGT GCCTGTGCCC 
CCCAACCTCT ATGGAGACTT CTTCACGGGT GACGCCTATG TCATCCTAAA GACGGTGCAG 
CTGAGGAATG GGAATCTGCA GTATGACCTC CACTATTGGC TGGGCAACGA GTGCAGCCAG 
GACGAGAGCG GGGCTGCCGC CATCTTTACC GTGCAGCTGG ATGACTACCT GAATGGCCGG 
GCTGTACAGC ACCGTGAGGT TCAGGGCTTT GAGTCGTCCA CATTCCAAGG CTACTTCAAG 
TCTGGACTTA AGTACAAGAA AGGAGGCGTG GCATCTGGAT TCAAACACGT GGTACCCAAC 
GAGGTGGTGG TGCAGAGGCT CTTCCAGGTC AAGGGACGCC GTGTAGTCCG TGCCACTGAA 
GTACCTGTGT CCTGGGACAG TTTCAACAAC GGTGACTGCT TCATTCTGGA CCTGGGAAAT 
AATATCTATC AGTGGTGTGG CTCCGGCAGC AACAAGTTTG AAAGACTGAA GGCCACGCAG 
GTGTCCAAGG GCATCCGGGA CAACGAGAGG AGTGGACGCG CCCAAGTACA TGTGTCTGAA 
GAGGGTAGCG AGCCGGAAGC CATGCTCCAG GTGCTGGGCC CCAAGCCGGA TCTGCCTCAG 
GGCACCGAGG ACACAGCCAA GGAAGATGCT GCCAACCGAA GGCTGGCCAA GCTCTACAAG 
GTCTCCAACA GTGGAGGCAG CATGTCAGTC TCCCTCGTGG CTGACGAGAA CCCCTTCGCC 
CAGTCCGCCC TGAGATCCGA GGACTGTTTC ATCCTGGACC ACGGCAGAGA TGGGAAAATC 
TTTGTTTGGA AAGGCAAGCA GGCCAACATG GATGAGCGGA AGGCTGCCCT CAAAACAGCC 
TCTGACTTCA TCTCCAAGAT GCAGTACCCC AGGCAGACCC AGGTTTCAGT CCTCCCGGAG 
GGCGGCGAGA CTCCTCTCTT TAAGCAGTTC TTCAAGAACT GGCGGGACCC AGACCAGACA 
GACGGCCCTG GCCTGAGCTA CCTCTCCAGC CACATTGCCA ACGTGGAGCG CGTGCCTTTC 
GATGCTGCTA CACTGCACAC CTCCACTGCC ATGGCTGCCC AGCACGGCAT GGATGATGAC 
GGAACTGGCC AGAAACAGAT CTGGAGAATT GAAGGTTCCA ACAAGGTACT GGTGGACCCC 
GCCACATATG GCCAGTTCTA TGGAGGTGAC AGCTACATCA TTCTGTACAA CTACCGCCAT 
GGTGGCCGCC AGGGACAGAT CATCTACAAC TGGCAGGGTG CCCAGTCTAC CCAGGATGAG 
GTCGCTGCTT CAGCCATCCT GACTGCCCAG CTGGATGAGG AACTGGGAGG AACTCCTGTC 
CAGAGCCGAG TGGTCCAAGG CAAAGAGCCT GCACACCTCA TGAGCTTGTT TGGTGGGAAG 
CCCATGATCA TCTACAAGGG CGGCACCTCC CGAGATGGTG GGCAGACAAC CCCTGCCAGT 
ACCCGCCTCT TCCAAGTCCG GGCCAGCAGC TCTGGAGCCA CCAGGGCTGT TGAGGTAATG 
CCTAAGGCTG GCGCTCTCAA CTCCAATGAT GCCTTTGTGC TGAAAACCCC CTCCGCCGCC 
TACCTGTGGG TGGGTACAGG AGCCAGTGAT GCGGAGAAGA CCGGCGCCCT GGAGCTGCTG 
AAGGTGCTGA GGGCCCAGCA CGTGCAGGTG GAGGAAGGCA GTGAACCAGA TGGCTTCTGG 
GAGGCTCTGG GCGGGAAGAC TGCCTACCGC ACATCCCCCA GGCTTAAGGA CAAGAAGATG 
GATGCTCATC CTCCTCGCCT CTTCGCCTGC TCCAACAGGA TCGGGCGCTT TGTGATCGAA 
GAGGTTCCTG GCGAGCTTAT GCAGGAAGAC CTGGCTACTG ATGACGTCAT GCTCCTGGAC 
ACCTGGGACC AGGTCTTTGT CTGGGTTGGA AAGGACTCTC AGGAAGAGGA AAAGACAGAA 
GCCTTGACCT CTGCTAAGCG GTACATCGAG ACGGACCCAG CGAATCGGGA CAGGCGGACC 
CCCATCACTG TCGTTAGGCA AGGCTTTGAG CCTCCTTCCT TTGTGGGCTG GTTCCTCGGC 
TGGGATGATG ACTACTGGTC GGTGGATCCC TTGGACCGGG CCTTGGCTGA GCTGGCTGCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gsn ( XM_006234040.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006234102.1 Rattus norvegicus gelsolin (Gsn), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa25768
Clone ID Related Accession (Same CDS sequence)	XM_006234040.2
Accession Version	XM_006234040.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2196bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	gelsolin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234040.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGGTGG AGCACCCCGA ATTCCTGAAG GCAGGGAAGG AGCCTGGCCT GCAGATCTGG 
CGTGTGGAGA AGTTTGACCT GGTGCCTGTG CCCCCCAACC TCTATGGAGA CTTCTTCACG 
GGTGACGCCT ATGTCATCCT AAAGACGGTG CAGCTGAGGA ATGGGAATCT GCAGTATGAC 
CTCCACTATT GGCTGGGCAA CGAGTGCAGC CAGGACGAGA GCGGGGCTGC CGCCATCTTT 
ACCGTGCAGC TGGATGACTA CCTGAATGGC CGGGCTGTAC AGCACCGTGA GGTTCAGGGC 
TTTGAGTCGT CCACATTCCA AGGCTACTTC AAGTCTGGAC TTAAGTACAA GAAAGGAGGC 
GTGGCATCTG GATTCAAACA CGTGGTACCC AACGAGGTGG TGGTGCAGAG GCTCTTCCAG 
GTCAAGGGAC GCCGTGTAGT CCGTGCCACT GAAGTACCTG TGTCCTGGGA CAGTTTCAAC 
AACGGTGACT GCTTCATTCT GGACCTGGGA AATAATATCT ATCAGTGGTG TGGCTCCGGC 
AGCAACAAGT TTGAAAGACT GAAGGCCACG CAGGTGTCCA AGGGCATCCG GGACAACGAG 
AGGAGTGGAC GCGCCCAAGT ACATGTGTCT GAAGAGGGTA GCGAGCCGGA AGCCATGCTC 
CAGGTGCTGG GCCCCAAGCC GGATCTGCCT CAGGGCACCG AGGACACAGC CAAGGAAGAT 
GCTGCCAACC GAAGGCTGGC CAAGCTCTAC AAGGTCTCCA ACAGTGGAGG CAGCATGTCA 
GTCTCCCTCG TGGCTGACGA GAACCCCTTC GCCCAGTCCG CCCTGAGATC CGAGGACTGT 
TTCATCCTGG ACCACGGCAG AGATGGGAAA ATCTTTGTTT GGAAAGGCAA GCAGGCCAAC 
ATGGATGAGC GGAAGGCTGC CCTCAAAACA GCCTCTGACT TCATCTCCAA GATGCAGTAC 
CCCAGGCAGA CCCAGGTTTC AGTCCTCCCG GAGGGCGGCG AGACTCCTCT CTTTAAGCAG 
TTCTTCAAGA ACTGGCGGGA CCCAGACCAG ACAGACGGCC CTGGCCTGAG CTACCTCTCC 
AGCCACATTG CCAACGTGGA GCGCGTGCCT TTCGATGCTG CTACACTGCA CACCTCCACT 
GCCATGGCTG CCCAGCACGG CATGGATGAT GACGGAACTG GCCAGAAACA GATCTGGAGA 
ATTGAAGGTT CCAACAAGGT ACTGGTGGAC CCCGCCACAT ATGGCCAGTT CTATGGAGGT 
GACAGCTACA TCATTCTGTA CAACTACCGC CATGGTGGCC GCCAGGGACA GATCATCTAC 
AACTGGCAGG GTGCCCAGTC TACCCAGGAT GAGGTCGCTG CTTCAGCCAT CCTGACTGCC 
CAGCTGGATG AGGAACTGGG AGGAACTCCT GTCCAGAGCC GAGTGGTCCA AGGCAAAGAG 
CCTGCACACC TCATGAGCTT GTTTGGTGGG AAGCCCATGA TCATCTACAA GGGCGGCACC 
TCCCGAGATG GTGGGCAGAC AACCCCTGCC AGTACCCGCC TCTTCCAAGT CCGGGCCAGC 
AGCTCTGGAG CCACCAGGGC TGTTGAGGTA ATGCCTAAGG CTGGCGCTCT CAACTCCAAT 
GATGCCTTTG TGCTGAAAAC CCCCTCCGCC GCCTACCTGT GGGTGGGTAC AGGAGCCAGT 
GATGCGGAGA AGACCGGCGC CCTGGAGCTG CTGAAGGTGC TGAGGGCCCA GCACGTGCAG 
GTGGAGGAAG GCAGTGAACC AGATGGCTTC TGGGAGGCTC TGGGCGGGAA GACTGCCTAC 
CGCACATCCC CCAGGCTTAA GGACAAGAAG ATGGATGCTC ATCCTCCTCG CCTCTTCGCC 
TGCTCCAACA GGATCGGGCG CTTTGTGATC GAAGAGGTTC CTGGCGAGCT TATGCAGGAA 
GACCTGGCTA CTGATGACGT CATGCTCCTG GACACCTGGG ACCAGGTCTT TGTCTGGGTT 
GGAAAGGACT CTCAGGAAGA GGAAAAGACA GAAGCCTTGA CCTCTGCTAA GCGGTACATC 
GAGACGGACC CAGCGAATCG GGACAGGCGG ACCCCCATCA CTGTCGTTAG GCAAGGCTTT 
GAGCCTCCTT CCTTTGTGGG CTGGTTCCTC GGCTGGGATG ATGACTACTG GTCGGTGGAT 
CCCTTGGACC GGGCCTTGGC TGAGCTGGCT GCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006234102.1
CDS	184..2379
Translation	MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFQGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSGSNKFERLKATQVSKGIRDNERSGRAQVHVSEEGSEPEAMLQVLGPKPDLPQGTEDTAKEDAANRRLAKLYKVSNSGGSMSVSLVADENPFAQSALRSEDCFILDHGRDGKIFVWKGKQANMDERKAALKTASDFISKMQYPRQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGPGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVLVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSRDGGQTTPASTRLFQVRASSSGATRAVEVMPKAGALNSNDAFVLKTPSAAYLWVGTGASDAEKTGALELLKVLRAQHVQVEEGSEPDGFWEALGGKTAYRTSPRLKDKKMDAHPPRLFACSNRIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVRQGFEPPSFVGWFLGWDDDYWSVDPLDRALAELAA

Target ORF information:

RefSeq Version	XM_006234040.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus gelsolin (Gsn), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006234040.2

ORF Insert Sequence:

ATGGTGGTGG AGCACCCCGA ATTCCTGAAG GCAGGGAAGG AGCCTGGCCT GCAGATCTGG 
CGTGTGGAGA AGTTTGACCT GGTGCCTGTG CCCCCCAACC TCTATGGAGA CTTCTTCACG 
GGTGACGCCT ATGTCATCCT AAAGACGGTG CAGCTGAGGA ATGGGAATCT GCAGTATGAC 
CTCCACTATT GGCTGGGCAA CGAGTGCAGC CAGGACGAGA GCGGGGCTGC CGCCATCTTT 
ACCGTGCAGC TGGATGACTA CCTGAATGGC CGGGCTGTAC AGCACCGTGA GGTTCAGGGC 
TTTGAGTCGT CCACATTCCA AGGCTACTTC AAGTCTGGAC TTAAGTACAA GAAAGGAGGC 
GTGGCATCTG GATTCAAACA CGTGGTACCC AACGAGGTGG TGGTGCAGAG GCTCTTCCAG 
GTCAAGGGAC GCCGTGTAGT CCGTGCCACT GAAGTACCTG TGTCCTGGGA CAGTTTCAAC 
AACGGTGACT GCTTCATTCT GGACCTGGGA AATAATATCT ATCAGTGGTG TGGCTCCGGC 
AGCAACAAGT TTGAAAGACT GAAGGCCACG CAGGTGTCCA AGGGCATCCG GGACAACGAG 
AGGAGTGGAC GCGCCCAAGT ACATGTGTCT GAAGAGGGTA GCGAGCCGGA AGCCATGCTC 
CAGGTGCTGG GCCCCAAGCC GGATCTGCCT CAGGGCACCG AGGACACAGC CAAGGAAGAT 
GCTGCCAACC GAAGGCTGGC CAAGCTCTAC AAGGTCTCCA ACAGTGGAGG CAGCATGTCA 
GTCTCCCTCG TGGCTGACGA GAACCCCTTC GCCCAGTCCG CCCTGAGATC CGAGGACTGT 
TTCATCCTGG ACCACGGCAG AGATGGGAAA ATCTTTGTTT GGAAAGGCAA GCAGGCCAAC 
ATGGATGAGC GGAAGGCTGC CCTCAAAACA GCCTCTGACT TCATCTCCAA GATGCAGTAC 
CCCAGGCAGA CCCAGGTTTC AGTCCTCCCG GAGGGCGGCG AGACTCCTCT CTTTAAGCAG 
TTCTTCAAGA ACTGGCGGGA CCCAGACCAG ACAGACGGCC CTGGCCTGAG CTACCTCTCC 
AGCCACATTG CCAACGTGGA GCGCGTGCCT TTCGATGCTG CTACACTGCA CACCTCCACT 
GCCATGGCTG CCCAGCACGG CATGGATGAT GACGGAACTG GCCAGAAACA GATCTGGAGA 
ATTGAAGGTT CCAACAAGGT ACTGGTGGAC CCCGCCACAT ATGGCCAGTT CTATGGAGGT 
GACAGCTACA TCATTCTGTA CAACTACCGC CATGGTGGCC GCCAGGGACA GATCATCTAC 
AACTGGCAGG GTGCCCAGTC TACCCAGGAT GAGGTCGCTG CTTCAGCCAT CCTGACTGCC 
CAGCTGGATG AGGAACTGGG AGGAACTCCT GTCCAGAGCC GAGTGGTCCA AGGCAAAGAG 
CCTGCACACC TCATGAGCTT GTTTGGTGGG AAGCCCATGA TCATCTACAA GGGCGGCACC 
TCCCGAGATG GTGGGCAGAC AACCCCTGCC AGTACCCGCC TCTTCCAAGT CCGGGCCAGC 
AGCTCTGGAG CCACCAGGGC TGTTGAGGTA ATGCCTAAGG CTGGCGCTCT CAACTCCAAT 
GATGCCTTTG TGCTGAAAAC CCCCTCCGCC GCCTACCTGT GGGTGGGTAC AGGAGCCAGT 
GATGCGGAGA AGACCGGCGC CCTGGAGCTG CTGAAGGTGC TGAGGGCCCA GCACGTGCAG 
GTGGAGGAAG GCAGTGAACC AGATGGCTTC TGGGAGGCTC TGGGCGGGAA GACTGCCTAC 
CGCACATCCC CCAGGCTTAA GGACAAGAAG ATGGATGCTC ATCCTCCTCG CCTCTTCGCC 
TGCTCCAACA GGATCGGGCG CTTTGTGATC GAAGAGGTTC CTGGCGAGCT TATGCAGGAA 
GACCTGGCTA CTGATGACGT CATGCTCCTG GACACCTGGG ACCAGGTCTT TGTCTGGGTT 
GGAAAGGACT CTCAGGAAGA GGAAAAGACA GAAGCCTTGA CCTCTGCTAA GCGGTACATC 
GAGACGGACC CAGCGAATCG GGACAGGCGG ACCCCCATCA CTGTCGTTAG GCAAGGCTTT 
GAGCCTCCTT CCTTTGTGGG CTGGTTCCTC GGCTGGGATG ATGACTACTG GTCGGTGGAT 
CCCTTGGACC GGGCCTTGGC TGAGCTGGCT GCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gsn ( XM_017591662.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447151.1 Rattus norvegicus gelsolin (Gsn), transcript variant X1, mRNA.

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CloneID	ORa25767
Clone ID Related Accession (Same CDS sequence)	XM_017591662.1
Accession Version	XM_017591662.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2229bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	gelsolin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAAAAC TCTTTTGTTG CTTTCCCAGC ACCATGGTGG TGGAGCACCC CGAATTCCTG 
AAGGCAGGGA AGGAGCCTGG CCTGCAGATC TGGCGTGTGG AGAAGTTTGA CCTGGTGCCT 
GTGCCCCCCA ACCTCTATGG AGACTTCTTC ACGGGTGACG CCTATGTCAT CCTAAAGACG 
GTGCAGCTGA GGAATGGGAA TCTGCAGTAT GACCTCCACT ATTGGCTGGG CAACGAGTGC 
AGCCAGGACG AGAGCGGGGC TGCCGCCATC TTTACCGTGC AGCTGGATGA CTACCTGAAT 
GGCCGGGCTG TACAGCACCG TGAGGTTCAG GGCTTTGAGT CGTCCACATT CCAAGGCTAC 
TTCAAGTCTG GACTTAAGTA CAAGAAAGGA GGCGTGGCAT CTGGATTCAA ACACGTGGTA 
CCCAACGAGG TGGTGGTGCA GAGGCTCTTC CAGGTCAAGG GACGCCGTGT AGTCCGTGCC 
ACTGAAGTAC CTGTGTCCTG GGACAGTTTC AACAACGGTG ACTGCTTCAT TCTGGACCTG 
GGAAATAATA TCTATCAGTG GTGTGGCTCC GGCAGCAACA AGTTTGAAAG ACTGAAGGCC 
ACGCAGGTGT CCAAGGGCAT CCGGGACAAC GAGAGGAGTG GACGCGCCCA AGTACATGTG 
TCTGAAGAGG GTAGCGAGCC GGAAGCCATG CTCCAGGTGC TGGGCCCCAA GCCGGATCTG 
CCTCAGGGCA CCGAGGACAC AGCCAAGGAA GATGCTGCCA ACCGAAGGCT GGCCAAGCTC 
TACAAGGTCT CCAACAGTGG AGGCAGCATG TCAGTCTCCC TCGTGGCTGA CGAGAACCCC 
TTCGCCCAGT CCGCCCTGAG ATCCGAGGAC TGTTTCATCC TGGACCACGG CAGAGATGGG 
AAAATCTTTG TTTGGAAAGG CAAGCAGGCC AACATGGATG AGCGGAAGGC TGCCCTCAAA 
ACAGCCTCTG ACTTCATCTC CAAGATGCAG TACCCCAGGC AGACCCAGGT TTCAGTCCTC 
CCGGAGGGCG GCGAGACTCC TCTCTTTAAG CAGTTCTTCA AGAACTGGCG GGACCCAGAC 
CAGACAGACG GCCCTGGCCT GAGCTACCTC TCCAGCCACA TTGCCAACGT GGAGCGCGTG 
CCTTTCGATG CTGCTACACT GCACACCTCC ACTGCCATGG CTGCCCAGCA CGGCATGGAT 
GATGACGGAA CTGGCCAGAA ACAGATCTGG AGAATTGAAG GTTCCAACAA GGTACTGGTG 
GACCCCGCCA CATATGGCCA GTTCTATGGA GGTGACAGCT ACATCATTCT GTACAACTAC 
CGCCATGGTG GCCGCCAGGG ACAGATCATC TACAACTGGC AGGGTGCCCA GTCTACCCAG 
GATGAGGTCG CTGCTTCAGC CATCCTGACT GCCCAGCTGG ATGAGGAACT GGGAGGAACT 
CCTGTCCAGA GCCGAGTGGT CCAAGGCAAA GAGCCTGCAC ACCTCATGAG CTTGTTTGGT 
GGGAAGCCCA TGATCATCTA CAAGGGCGGC ACCTCCCGAG ATGGTGGGCA GACAACCCCT 
GCCAGTACCC GCCTCTTCCA AGTCCGGGCC AGCAGCTCTG GAGCCACCAG GGCTGTTGAG 
GTAATGCCTA AGGCTGGCGC TCTCAACTCC AATGATGCCT TTGTGCTGAA AACCCCCTCC 
GCCGCCTACC TGTGGGTGGG TACAGGAGCC AGTGATGCGG AGAAGACCGG CGCCCTGGAG 
CTGCTGAAGG TGCTGAGGGC CCAGCACGTG CAGGTGGAGG AAGGCAGTGA ACCAGATGGC 
TTCTGGGAGG CTCTGGGCGG GAAGACTGCC TACCGCACAT CCCCCAGGCT TAAGGACAAG 
AAGATGGATG CTCATCCTCC TCGCCTCTTC GCCTGCTCCA ACAGGATCGG GCGCTTTGTG 
ATCGAAGAGG TTCCTGGCGA GCTTATGCAG GAAGACCTGG CTACTGATGA CGTCATGCTC 
CTGGACACCT GGGACCAGGT CTTTGTCTGG GTTGGAAAGG ACTCTCAGGA AGAGGAAAAG 
ACAGAAGCCT TGACCTCTGC TAAGCGGTAC ATCGAGACGG ACCCAGCGAA TCGGGACAGG 
CGGACCCCCA TCACTGTCGT TAGGCAAGGC TTTGAGCCTC CTTCCTTTGT GGGCTGGTTC 
CTCGGCTGGG ATGATGACTA CTGGTCGGTG GATCCCTTGG ACCGGGCCTT GGCTGAGCTG 
GCTGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447151.1
CDS	222..2450
Translation	MEKLFCCFPSTMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFQGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSGSNKFERLKATQVSKGIRDNERSGRAQVHVSEEGSEPEAMLQVLGPKPDLPQGTEDTAKEDAANRRLAKLYKVSNSGGSMSVSLVADENPFAQSALRSEDCFILDHGRDGKIFVWKGKQANMDERKAALKTASDFISKMQYPRQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGPGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVLVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSRDGGQTTPASTRLFQVRASSSGATRAVEVMPKAGALNSNDAFVLKTPSAAYLWVGTGASDAEKTGALELLKVLRAQHVQVEEGSEPDGFWEALGGKTAYRTSPRLKDKKMDAHPPRLFACSNRIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVRQGFEPPSFVGWFLGWDDDYWSVDPLDRALAELAA

Target ORF information:

RefSeq Version	XM_017591662.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus gelsolin (Gsn), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017591662.1

ORF Insert Sequence:

ATGGAAAAAC TCTTTTGTTG CTTTCCCAGC ACCATGGTGG TGGAGCACCC CGAATTCCTG 
AAGGCAGGGA AGGAGCCTGG CCTGCAGATC TGGCGTGTGG AGAAGTTTGA CCTGGTGCCT 
GTGCCCCCCA ACCTCTATGG AGACTTCTTC ACGGGTGACG CCTATGTCAT CCTAAAGACG 
GTGCAGCTGA GGAATGGGAA TCTGCAGTAT GACCTCCACT ATTGGCTGGG CAACGAGTGC 
AGCCAGGACG AGAGCGGGGC TGCCGCCATC TTTACCGTGC AGCTGGATGA CTACCTGAAT 
GGCCGGGCTG TACAGCACCG TGAGGTTCAG GGCTTTGAGT CGTCCACATT CCAAGGCTAC 
TTCAAGTCTG GACTTAAGTA CAAGAAAGGA GGCGTGGCAT CTGGATTCAA ACACGTGGTA 
CCCAACGAGG TGGTGGTGCA GAGGCTCTTC CAGGTCAAGG GACGCCGTGT AGTCCGTGCC 
ACTGAAGTAC CTGTGTCCTG GGACAGTTTC AACAACGGTG ACTGCTTCAT TCTGGACCTG 
GGAAATAATA TCTATCAGTG GTGTGGCTCC GGCAGCAACA AGTTTGAAAG ACTGAAGGCC 
ACGCAGGTGT CCAAGGGCAT CCGGGACAAC GAGAGGAGTG GACGCGCCCA AGTACATGTG 
TCTGAAGAGG GTAGCGAGCC GGAAGCCATG CTCCAGGTGC TGGGCCCCAA GCCGGATCTG 
CCTCAGGGCA CCGAGGACAC AGCCAAGGAA GATGCTGCCA ACCGAAGGCT GGCCAAGCTC 
TACAAGGTCT CCAACAGTGG AGGCAGCATG TCAGTCTCCC TCGTGGCTGA CGAGAACCCC 
TTCGCCCAGT CCGCCCTGAG ATCCGAGGAC TGTTTCATCC TGGACCACGG CAGAGATGGG 
AAAATCTTTG TTTGGAAAGG CAAGCAGGCC AACATGGATG AGCGGAAGGC TGCCCTCAAA 
ACAGCCTCTG ACTTCATCTC CAAGATGCAG TACCCCAGGC AGACCCAGGT TTCAGTCCTC 
CCGGAGGGCG GCGAGACTCC TCTCTTTAAG CAGTTCTTCA AGAACTGGCG GGACCCAGAC 
CAGACAGACG GCCCTGGCCT GAGCTACCTC TCCAGCCACA TTGCCAACGT GGAGCGCGTG 
CCTTTCGATG CTGCTACACT GCACACCTCC ACTGCCATGG CTGCCCAGCA CGGCATGGAT 
GATGACGGAA CTGGCCAGAA ACAGATCTGG AGAATTGAAG GTTCCAACAA GGTACTGGTG 
GACCCCGCCA CATATGGCCA GTTCTATGGA GGTGACAGCT ACATCATTCT GTACAACTAC 
CGCCATGGTG GCCGCCAGGG ACAGATCATC TACAACTGGC AGGGTGCCCA GTCTACCCAG 
GATGAGGTCG CTGCTTCAGC CATCCTGACT GCCCAGCTGG ATGAGGAACT GGGAGGAACT 
CCTGTCCAGA GCCGAGTGGT CCAAGGCAAA GAGCCTGCAC ACCTCATGAG CTTGTTTGGT 
GGGAAGCCCA TGATCATCTA CAAGGGCGGC ACCTCCCGAG ATGGTGGGCA GACAACCCCT 
GCCAGTACCC GCCTCTTCCA AGTCCGGGCC AGCAGCTCTG GAGCCACCAG GGCTGTTGAG 
GTAATGCCTA AGGCTGGCGC TCTCAACTCC AATGATGCCT TTGTGCTGAA AACCCCCTCC 
GCCGCCTACC TGTGGGTGGG TACAGGAGCC AGTGATGCGG AGAAGACCGG CGCCCTGGAG 
CTGCTGAAGG TGCTGAGGGC CCAGCACGTG CAGGTGGAGG AAGGCAGTGA ACCAGATGGC 
TTCTGGGAGG CTCTGGGCGG GAAGACTGCC TACCGCACAT CCCCCAGGCT TAAGGACAAG 
AAGATGGATG CTCATCCTCC TCGCCTCTTC GCCTGCTCCA ACAGGATCGG GCGCTTTGTG 
ATCGAAGAGG TTCCTGGCGA GCTTATGCAG GAAGACCTGG CTACTGATGA CGTCATGCTC 
CTGGACACCT GGGACCAGGT CTTTGTCTGG GTTGGAAAGG ACTCTCAGGA AGAGGAAAAG 
ACAGAAGCCT TGACCTCTGC TAAGCGGTAC ATCGAGACGG ACCCAGCGAA TCGGGACAGG 
CGGACCCCCA TCACTGTCGT TAGGCAAGGC TTTGAGCCTC CTTCCTTTGT GGGCTGGTTC 
CTCGGCTGGG ATGATGACTA CTGGTCGGTG GATCCCTTGG ACCGGGCCTT GGCTGAGCTG 
GCTGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LINGO-1 Regulates Oligodendrocyte Differentiation through the Cytoplasmic Gelsolin Signaling Pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience37(12)3127-3137(2017 Mar)
Shao Z,Lee X,Huang G,Sheng G,Henderson CE,Louvard D,Sohn J,Pepinsky B,Mi S

Hypoxia Augments Increased HIF-1? and Reduced Survival Protein p-Akt in Gelsolin (GSN)-Dependent Cardiomyoblast Cell Apoptosis.
Cell biochemistry and biophysics74(2)221-8(2016 Jun)
Yeh YL,Ting WJ,Shen CY,Hsu HH,Chung LC,Tu CC,Chang SH,Day CH,Tsai Y,Huang CY

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Cardiovascular research110(3)419-30(2016 06)
Barallobre-Barreiro J,Oklu R,Lynch M,Fava M,Baig F,Yin X,Barwari T,Potier DN,Albadawi H,Jahangiri M,Porter KE,Watkins MT,Misra S,Stoughton J,Mayr M

Expression of Cytoplasmic Gelsolin in Rat Brain After Experimental Subarachnoid Hemorrhage.
Cellular and molecular neurobiology35(5)723-31(2015 Jul)
Xie GB,Wang CX,Zhou CH,Li H,Zhang XS,Zhou XM,Zhang L,Hang CH,Zhou ML,Shi JX

The Stress-Induced Atf3-Gelsolin Cascade Underlies Dendritic Spine Deficits in Neuronal Models of Tuberous Sclerosis Complex.
The Journal of neuroscience : the official journal of the Society for Neuroscience35(30)10762-72(2015 Jul)
Nie D,Chen Z,Ebrahimi-Fakhari D,Di Nardo A,Julich K,Robson VK,Cheng YC,Woolf CJ,Heiman M,Sahin M

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Gsn cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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