Pmpca cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pmpca
Entrez Gene ID	296588
Full Name	peptidase, mitochondrial processing alpha subunit
General protein information	Preferred Names peptidase, mitochondrial processing alpha subunit Names mitochondrial-processing peptidase subunit alpha P-55 alpha-MPP mitochondrial processing peptidase alpha subunit, mitochondrial peptidase (mitochondrial processing) alpha
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3p13
Summary	alpha subunit of the general mitochondrial matrix processing protease [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017591640.1	XP_017447129.1	mitochondrial-processing peptidase subunit alpha isoform X1
NM_001003673.1	NP_001003673.1	mitochondrial-processing peptidase subunit alpha

Pathways from BioSystems

Homologies

	PMPCA	XP_002799969.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008086	XP_317371.3
Pan troglodytes (chimpanzee)	PMPCA	XP_003312459.1
Drosophila melanogaster (fruit fly)	CG8728	NP_610333.1
Danio rerio (zebrafish)	pmpca	NP_001007443.1
Schizosaccharomyces pombe (fission yeast)	mas2	NP_595859.2
Oryza sativa (rice)	Os01g0966300	NP_001045501.1
Canis lupus familiaris (dog)	PMPCA	XP_537796.1
Mus musculus (house mouse)	Pmpca	NP_775272.1
Saccharomyces cerevisiae (baker's yeast)	MAS2	NP_011889.1
Xenopus tropicalis (tropical clawed frog)	pmpca	XP_002935264.1
Homo sapiens (human)	PMPCA	NP_055975.1
Bos taurus (cattle)	PMPCA	NP_001070432.1
Rattus norvegicus (Norway rat)	Pmpca	NP_001003673.1
Gallus gallus (chicken)	PMPCA	NP_001006197.1
Caenorhabditis elegans (roundworm)	mppa-1	NP_490888.1
Kluyveromyces lactis	KLLA0E11573g	XP_454472.1
Magnaporthe oryzae (rice blast fungus)	MGG_05258	XP_003712815.1
Neurospora crassa	NCU06270	XP_962874.1

Gene Ontology
Bibliography

Related articles in PubMed

PMPCA mutations cause abnormal mitochondrial protein processing in patients with non-progressive cerebellar ataxia.
Jobling RK, Assoum M, Gakh O, Blaser S, Raiman JA, Mignot C, Roze E, D?rr A, Brice A, L?vy N, Prasad C, Paton T, Paterson AD, Roslin NM, Marshall CR, Desvignes JP, Ro?ckel-Trevisiol N, Scherer SW, Rouleau GA, M?garban? A, Isaya G, Delague V, Yoon G
Brain : a journal of neurology138(Pt 6)1505-17(2015 Jun)

Processing of mitochondrial presequences.
Mossmann D, Meisinger C, V?gtle FN
Biochimica et biophysica acta1819(9-10)1098-106(2012 Sep-Oct)

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.
B?hm D, Keller K, Pieter J, Boehm N, Wolters D, Siggelkow W, Lebrecht A, Schmidt M, K?lbl H, Pfeiffer N, Grus FH
Oncology reports28(2)429-38(2012 Aug)

A putative metal-binding site in the beta subunit of rat mitochondrial processing peptidase is essential for its catalytic activity.
Kitada S, Shimokata K, Niidome T, Ogishima T, Ito A
Journal of biochemistry117(6)1148-50(1995 Jun)

The general mitochondrial matrix processing protease from rat liver: structural characterization of the catalytic subunit.
Kleiber J, Kalousek F, Swaroop M, Rosenberg LE
Proceedings of the National Academy of Sciences of the United States of America87(20)7978-82(1990 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Pmpca gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pmpca cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12404	NM_001003673.1 Latest version!	Rattus norvegicus peptidase, mitochondrial processing subunit alpha (Pmpca), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa60364	XM_017591640.1 Latest version!	Rattus norvegicus peptidase, mitochondrial processing alpha subunit (Pmpca), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pmpca ( NM_001003673.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001003673.1 Rattus norvegicus peptidase, mitochondrial processing subunit alpha (Pmpca), mRNA.

Price & Availability↑

CloneID	ORa12404
Clone ID Related Accession (Same CDS sequence)	NM_001003673.1
Accession Version	NM_001003673.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1575bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-10
Organism	Rattus norvegicus(Norway rat)
Product	mitochondrial-processing peptidase subunit alpha
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC079004.1 and CB806391.1. On Oct 18, 2004 this sequence version replaced XM_215989.1. ##Evidence-Data-START## Transcript exon combination :: BC079004.1, M57728.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGGCGACGG CAGTGTGGGC GGCTGCGCGG CTACTTCGGG GTTCTGCGGC GCTGTGCGCG 
CGGCCCAAGT TCGGTTCTCC TGCACACAGA CGGTTCAGCA GTGGCGCCAC CTACCCCAAC 
ATCCCTCTCT CTTCTCCCTT GCCCGGAGTG CCCAAGCCTA TTTTTGCTAC AGTTGATGGA 
CAGGAAAAGT TTGAAACCAA AGTCACCACT CTGGACAATG GGCTTCGTGT GGCATCTCAA 
AATAAGTTTG GACAGTTCTG TACCTTAGGA ATTCTTATTA ATTCAGGATC ACGATATGAA 
GCGAAATATC TTAGTGGAAT TGCTCATTTT CTGGAAAAAT TGGCATTTTC GTCTACCGCT 
CGATTTGACA GCAAAGATGA AATTCTGCTT ACCCTGGAAA AACATGGTGG TATCTGTGAC 
TGCCAGACCT CGAGAGACAC CACCATGTAT GCTGTGTCTG CTGACAGCAA AGGCTTGGAC 
ACTGTGGTGG GCCTGCTGGC TGATGTGGTT CTGCACCCCC GCCTGACAGA TGAGGAAATT 
GAGATGACGA GGATGGCTGT TCAGTTTGAA CTTGAGGACC TGAACATGAG ACCTGACCCA 
GAGCCACTGC TCACCGAGAT GATTCATGAA GCTGCTTTTA GGGAGAACAC GGTGGGCCTG 
CACCGGTTTT GTCCTGTAGA GAACATAGGG AAGATTGACC GAGAAGTGCT GCATTCCTAC 
CTGAAGAACT ACTACACCCC CGACCGCATG GTGCTTGCTG GAGTGGGCGT GGAGCATGAG 
CACCTGGTCG AATGTGCCAG AAAGTACCTC CTGGGAGTGC AGCCTGCCTG GGGAGCTCCG 
GGAGCTGTGG ATGTTGACAG CTCAGTGGCA CAGTACACGG GGGGGATCAT CAAGGTGGAG 
AGAGACATGT CAAATGTCAG CCTTGGCCCC ACCCCGATTC CAGAGCTCAC ACATATCATG 
GTGGGGCTAG AGAGCTGCTC CTTCCTGGAG GAGGATTTCA TCCCCTTTGC TGTGTTGAAT 
ATGATGATGG GAGGCGGGGG CTCCTTCTCG GCCGGAGGGC CTGGCAAAGG CATGTTCTCC 
AGGCTCTACC TCAACGTGCT CAATCGGCAC CACTGGATGT ATAATGCAAC CTCCTACCAC 
CACAGCTATG AAGACACAGG CCTCCTGTGC ATCCATGCCA GCGCAGACCC TCGACAGGTT 
CGAGAAATGG TAGAAATCAT CACAAAGGAG TTTATTTTGA TGGGCCGAAC GGTGGATTTG 
GTGGAGCTGG AGCGGGCCAA GACACAGCTG ATGTCCATGC TCATGATGAA CTTGGAGTCC 
AGGCCTGTGA TCTTTGAGGA TGTGGGGAGG CAGGTGTTGG CTACACATTC AAGAAAGCTG 
CCCCATGAGC TGTGCACACT CATTCGCAAT GTGAAGCCGG AAGATATCAA GAGGGTTGCT 
TCCAAGATGC TCCGAGGCAA GCCTGCTGTG GCCGCTCTGG GTGATTTGAC TGACCTGCCC 
ACGTATGAAC ACATCCAGGC AGCGCTGTCC AGCAGAGATG GGCGCCTGCC CAGAACATAC 
CGGCTGTTCC GGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003673.1
CDS	7..1581
Translation	MATAVWAAARLLRGSAALCARPKFGSPAHRRFSSGATYPNIPLSSPLPGVPKPIFATVDGQEKFETKVTTLDNGLRVASQNKFGQFCTLGILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVGLLADVVLHPRLTDEEIEMTRMAVQFELEDLNMRPDPEPLLTEMIHEAAFRENTVGLHRFCPVENIGKIDREVLHSYLKNYYTPDRMVLAGVGVEHEHLVECARKYLLGVQPAWGAPGAVDVDSSVAQYTGGIIKVERDMSNVSLGPTPIPELTHIMVGLESCSFLEEDFIPFAVLNMMMGGGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGRTVDLVELERAKTQLMSMLMMNLESRPVIFEDVGRQVLATHSRKLPHELCTLIRNVKPEDIKRVASKMLRGKPAVAALGDLTDLPTYEHIQAALSSRDGRLPRTYRLFR

Target ORF information:

RefSeq Version	NM_001003673.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus peptidase, mitochondrial processing subunit alpha (Pmpca), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003673.1

ORF Insert Sequence:

ATGGCGACGG CAGTGTGGGC GGCTGCGCGG CTACTTCGGG GTTCTGCGGC GCTGTGCGCG 
CGGCCCAAGT TCGGTTCTCC TGCACACAGA CGGTTCAGCA GTGGCGCCAC CTACCCCAAC 
ATCCCTCTCT CTTCTCCCTT GCCCGGAGTG CCCAAGCCTA TTTTTGCTAC AGTTGATGGA 
CAGGAAAAGT TTGAAACCAA AGTCACCACT CTGGACAATG GGCTTCGTGT GGCATCTCAA 
AATAAGTTTG GACAGTTCTG TACCTTAGGA ATTCTTATTA ATTCAGGATC ACGATATGAA 
GCGAAATATC TTAGTGGAAT TGCTCATTTT CTGGAAAAAT TGGCATTTTC GTCTACCGCT 
CGATTTGACA GCAAAGATGA AATTCTGCTT ACCCTGGAAA AACATGGTGG TATCTGTGAC 
TGCCAGACCT CGAGAGACAC CACCATGTAT GCTGTGTCTG CTGACAGCAA AGGCTTGGAC 
ACTGTGGTGG GCCTGCTGGC TGATGTGGTT CTGCACCCCC GCCTGACAGA TGAGGAAATT 
GAGATGACGA GGATGGCTGT TCAGTTTGAA CTTGAGGACC TGAACATGAG ACCTGACCCA 
GAGCCACTGC TCACCGAGAT GATTCATGAA GCTGCTTTTA GGGAGAACAC GGTGGGCCTG 
CACCGGTTTT GTCCTGTAGA GAACATAGGG AAGATTGACC GAGAAGTGCT GCATTCCTAC 
CTGAAGAACT ACTACACCCC CGACCGCATG GTGCTTGCTG GAGTGGGCGT GGAGCATGAG 
CACCTGGTCG AATGTGCCAG AAAGTACCTC CTGGGAGTGC AGCCTGCCTG GGGAGCTCCG 
GGAGCTGTGG ATGTTGACAG CTCAGTGGCA CAGTACACGG GGGGGATCAT CAAGGTGGAG 
AGAGACATGT CAAATGTCAG CCTTGGCCCC ACCCCGATTC CAGAGCTCAC ACATATCATG 
GTGGGGCTAG AGAGCTGCTC CTTCCTGGAG GAGGATTTCA TCCCCTTTGC TGTGTTGAAT 
ATGATGATGG GAGGCGGGGG CTCCTTCTCG GCCGGAGGGC CTGGCAAAGG CATGTTCTCC 
AGGCTCTACC TCAACGTGCT CAATCGGCAC CACTGGATGT ATAATGCAAC CTCCTACCAC 
CACAGCTATG AAGACACAGG CCTCCTGTGC ATCCATGCCA GCGCAGACCC TCGACAGGTT 
CGAGAAATGG TAGAAATCAT CACAAAGGAG TTTATTTTGA TGGGCCGAAC GGTGGATTTG 
GTGGAGCTGG AGCGGGCCAA GACACAGCTG ATGTCCATGC TCATGATGAA CTTGGAGTCC 
AGGCCTGTGA TCTTTGAGGA TGTGGGGAGG CAGGTGTTGG CTACACATTC AAGAAAGCTG 
CCCCATGAGC TGTGCACACT CATTCGCAAT GTGAAGCCGG AAGATATCAA GAGGGTTGCT 
TCCAAGATGC TCCGAGGCAA GCCTGCTGTG GCCGCTCTGG GTGATTTGAC TGACCTGCCC 
ACGTATGAAC ACATCCAGGC AGCGCTGTCC AGCAGAGATG GGCGCCTGCC CAGAACATAC 
CGGCTGTTCC GGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pmpca ( XM_017591640.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447129.1 Rattus norvegicus peptidase, mitochondrial processing alpha subunit (Pmpca), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa60364
Clone ID Related Accession (Same CDS sequence)	XM_017591640.1
Accession Version	XM_017591640.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1278bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	mitochondrial-processing peptidase subunit alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCGAA ATATCTTAGT GGAATTGCTC ATTTTCTGGA AAAATTGGCA TTTTCGTCTA 
CCGCTCGATT TGACAGCAAA GATGAAATTC TGCTTACCCT GGAAAAACAT GGTGGTATCT 
GTGACTGCCA GACCTCGAGA CACCACCATG TATGCTGTGT CTGCTGACAG CAAAGGCTTG 
GACACTGTGG TGGGCCTGCT GGCTGATGTG GTTCTGCACC CCCGCCTGAC AGATGAGGAA 
ATTGAGATGA CGAGGATGGC TGTTCAGTTT GAACTTGAGG ACCTGAACAT GAGACCTGAC 
CCAGAGCCAC TGCTCACCGA GATGATTCAT GAAGCTGCTT TTAGGGAGAA CACGGTGGGC 
CTGCACCGGT TTTGTCCTGT AGAGAACATA GGGAAGATTG ACCGAGAAGT GCTGCATTCC 
TACCTGAAGA ACTACTACAC CCCCGACCGC ATGGTGCTTG CTGGAGTGGG CGTGGAGCAT 
GAGCACCTGG TCGAATGTGC CAGAAAGTAC CTCCTGGGAG TGCAGCCTGC CTGGGGAGCT 
CCGGGAGCTG TGGATGTTGA CAGCTCAGTG GCACAGTACA CGGGGGGGAT CATCAAGGTG 
GAGAGAGACA TGTCAAATGT CAGCCTTGGC CCCACCCCGA TTCCAGAGCT CACACATATC 
ATGGTGGGGC TAGAGAGCTG CTCCTTCCTG GAGGAGGATT TCATCCCCTT TGCTGTGTTG 
AATATGATGA TGGGAGGCGG GGGCTCCTTC TCGGCCGGAG GGCCTGGCAA AGGCATGTTC 
TCCAGGCTCT ACCTCAACGT GCTCAATCGG CACCACTGGA TGTATAATGC AACCTCCTAC 
CACCACAGCT ATGAAGACAC AGGCCTCCTG TGCATCCATG CCAGCGCAGA CCCTCGACAG 
GTTCGAGAAA TGGTAGAAAT CATCACAAAG GAGTTTATTT TGATGGGCCG AACGGTGGAT 
TTGGTGGAGC TGGAGCGGGC CAAGACACAG CTGATGTCCA TGCTCATGAT GAACTTGGAG 
TCCAGGCCTG TGATCTTTGA GGATGTGGGG AGGCAGGTGT TGGCTACACA TTCAAGAAAG 
CTGCCCCATG AGCTGTGCAC ACTCATTCGC AATGTGAAGC CGGAAGATAT CAAGAGGGTT 
GCTTCCAAGA TGCTCCGAGG CAAGCCTGCT GTGGCCGCTC TGGGTGATTT GACTGACCTG 
CCCACGTATG AACACATCCA GGCAGCGCTG TCCAGCAGAG ATGGGCGCCT GCCCAGAACA 
TACCGGCTGT TCCGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447129.1
CDS	1..1278
Translation	MKRNILVELLIFWKNWHFRLPLDLTAKMKFCLPWKNMVVSVTARPRDTTMYAVSADSKGLDTVVGLLADVVLHPRLTDEEIEMTRMAVQFELEDLNMRPDPEPLLTEMIHEAAFRENTVGLHRFCPVENIGKIDREVLHSYLKNYYTPDRMVLAGVGVEHEHLVECARKYLLGVQPAWGAPGAVDVDSSVAQYTGGIIKVERDMSNVSLGPTPIPELTHIMVGLESCSFLEEDFIPFAVLNMMMGGGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGRTVDLVELERAKTQLMSMLMMNLESRPVIFEDVGRQVLATHSRKLPHELCTLIRNVKPEDIKRVASKMLRGKPAVAALGDLTDLPTYEHIQAALSSRDGRLPRTYRLFR

Target ORF information:

RefSeq Version	XM_017591640.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus peptidase, mitochondrial processing alpha subunit (Pmpca), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017591640.1

ORF Insert Sequence:

ATGAAGCGAA ATATCTTAGT GGAATTGCTC ATTTTCTGGA AAAATTGGCA TTTTCGTCTA 
CCGCTCGATT TGACAGCAAA GATGAAATTC TGCTTACCCT GGAAAAACAT GGTGGTATCT 
GTGACTGCCA GACCTCGAGA CACCACCATG TATGCTGTGT CTGCTGACAG CAAAGGCTTG 
GACACTGTGG TGGGCCTGCT GGCTGATGTG GTTCTGCACC CCCGCCTGAC AGATGAGGAA 
ATTGAGATGA CGAGGATGGC TGTTCAGTTT GAACTTGAGG ACCTGAACAT GAGACCTGAC 
CCAGAGCCAC TGCTCACCGA GATGATTCAT GAAGCTGCTT TTAGGGAGAA CACGGTGGGC 
CTGCACCGGT TTTGTCCTGT AGAGAACATA GGGAAGATTG ACCGAGAAGT GCTGCATTCC 
TACCTGAAGA ACTACTACAC CCCCGACCGC ATGGTGCTTG CTGGAGTGGG CGTGGAGCAT 
GAGCACCTGG TCGAATGTGC CAGAAAGTAC CTCCTGGGAG TGCAGCCTGC CTGGGGAGCT 
CCGGGAGCTG TGGATGTTGA CAGCTCAGTG GCACAGTACA CGGGGGGGAT CATCAAGGTG 
GAGAGAGACA TGTCAAATGT CAGCCTTGGC CCCACCCCGA TTCCAGAGCT CACACATATC 
ATGGTGGGGC TAGAGAGCTG CTCCTTCCTG GAGGAGGATT TCATCCCCTT TGCTGTGTTG 
AATATGATGA TGGGAGGCGG GGGCTCCTTC TCGGCCGGAG GGCCTGGCAA AGGCATGTTC 
TCCAGGCTCT ACCTCAACGT GCTCAATCGG CACCACTGGA TGTATAATGC AACCTCCTAC 
CACCACAGCT ATGAAGACAC AGGCCTCCTG TGCATCCATG CCAGCGCAGA CCCTCGACAG 
GTTCGAGAAA TGGTAGAAAT CATCACAAAG GAGTTTATTT TGATGGGCCG AACGGTGGAT 
TTGGTGGAGC TGGAGCGGGC CAAGACACAG CTGATGTCCA TGCTCATGAT GAACTTGGAG 
TCCAGGCCTG TGATCTTTGA GGATGTGGGG AGGCAGGTGT TGGCTACACA TTCAAGAAAG 
CTGCCCCATG AGCTGTGCAC ACTCATTCGC AATGTGAAGC CGGAAGATAT CAAGAGGGTT 
GCTTCCAAGA TGCTCCGAGG CAAGCCTGCT GTGGCCGCTC TGGGTGATTT GACTGACCTG 
CCCACGTATG AACACATCCA GGCAGCGCTG TCCAGCAGAG ATGGGCGCCT GCCCAGAACA 
TACCGGCTGT TCCGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PMPCA mutations cause abnormal mitochondrial protein processing in patients with non-progressive cerebellar ataxia.
Brain : a journal of neurology138(Pt 6)1505-17(2015 Jun)
Jobling RK,Assoum M,Gakh O,Blaser S,Raiman JA,Mignot C,Roze E,D?rr A,Brice A,L?vy N,Prasad C,Paton T,Paterson AD,Roslin NM,Marshall CR,Desvignes JP,Ro?ckel-Trevisiol N,Scherer SW,Rouleau GA,M?garban? A,Isaya G,Delague V,Yoon G

Processing of mitochondrial presequences.
Biochimica et biophysica acta1819(9-10)1098-106(2012 Sep-Oct)
Mossmann D,Meisinger C,V?gtle FN

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.
Oncology reports28(2)429-38(2012 Aug)
B?hm D,Keller K,Pieter J,Boehm N,Wolters D,Siggelkow W,Lebrecht A,Schmidt M,K?lbl H,Pfeiffer N,Grus FH

A putative metal-binding site in the beta subunit of rat mitochondrial processing peptidase is essential for its catalytic activity.
Journal of biochemistry117(6)1148-50(1995 Jun)
Kitada S,Shimokata K,Niidome T,Ogishima T,Ito A

The general mitochondrial matrix processing protease from rat liver: structural characterization of the catalytic subunit.
Proceedings of the National Academy of Sciences of the United States of America87(20)7978-82(1990 Oct)
Kleiber J,Kalousek F,Swaroop M,Rosenberg LE

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Pmpca cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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