Ptprj cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ptprj
Entrez Gene ID	29645
Full Name	protein tyrosine phosphatase, receptor type, J
Synonyms	DEP-1
General protein information	Preferred Names protein tyrosine phosphatase, receptor type, J Names receptor-type tyrosine-protein phosphatase eta density enhanced phosphatase-1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q24
Summary	protein tyrosine phosphatase expressed in smooth muscle cells; may be involved in cell adhesion or cell-cell signaling [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_017269.2	NP_058965.2	receptor-type tyrosine-protein phosphatase eta

Pathways from BioSystems

Homologies

Homo sapiens (human)	PTPRJ	NP_002834.3
Pan troglodytes (chimpanzee)	PTPRJ	XP_508422.3
	PTPRJ	XP_002799618.1
Mus musculus (house mouse)	Ptprj	NP_033008.3
Gallus gallus (chicken)	PTPRJ	NP_989952.1
Canis lupus familiaris (dog)	PTPRJ	XP_540737.3
Rattus norvegicus (Norway rat)	Ptprj	NP_058965.2
Bos taurus (cattle)	PTPRJ	XP_003587065.2
Danio rerio (zebrafish)	ptprja	NP_001129714.1

Gene Ontology
Bibliography

Related articles in PubMed

Defining the molecular basis of interaction between R3 receptor-type protein tyrosine phosphatases and VE-cadherin.
Dorofejeva O, Barr AJ
PloS one12(9)e0184574(2017)

Loss of the protein-tyrosine phosphatase DEP-1/PTPRJ drives meningioma cell motility.
Petermann A, Haase D, Wetzel A, Balavenkatraman KK, Tenev T, G?hrs KH, Friedrich S, Nakamura M, Mawrin C, B?hmer FD
Brain pathology (Zurich, Switzerland)21(4)405-18(2011 Jul)

Phosphatome profiling reveals PTPN2, PTPRJ and PTEN as potent negative regulators of PKB/Akt activation in Ras-mutated cancer cells.
Omerovic J, Clague MJ, Prior IA
The Biochemical journal426(1)65-72(2010 Jan)

An unbiased screen identifies DEP-1 tumor suppressor as a phosphatase controlling EGFR endocytosis.
Tarcic G, Boguslavsky SK, Wakim J, Kiuchi T, Liu A, Reinitz F, Nathanson D, Takahashi T, Mischel PS, Ng T, Yarden Y
Current biology : CB19(21)1788-98(2009 Nov)

Tumor suppressor density-enhanced phosphatase-1 (DEP-1) inhibits the RAS pathway by direct dephosphorylation of ERK1/2 kinases.
Sacco F, Tinti M, Palma A, Ferrari E, Nardozza AP, Hooft van Huijsduijnen R, Takahashi T, Castagnoli L, Cesareni G
The Journal of biological chemistry284(33)22048-58(2009 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue
Title: The rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue.

propose that the expression and activation of DEP-1/PTPeta is required for somatostatin inhibition of glioma proliferation
Title: The expression of the phosphotyrosine phosphatase DEP-1/PTPeta dictates the responsivity of glioma cells to somatostatin inhibition of cell proliferation.

The following Ptprj gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ptprj cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa41712	NM_017269.2 Latest version!	Rattus norvegicus protein tyrosine phosphatase, receptor type, J (Ptprj), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ptprj ( NM_017269.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_058965.2 Rattus norvegicus protein tyrosine phosphatase, receptor type, J (Ptprj), mRNA.

Price & Availability↑

CloneID	ORa41712
Clone ID Related Accession (Same CDS sequence)	NM_017269.2
Accession Version	NM_017269.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3870bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Rattus norvegicus(Norway rat)
Product	receptor-type tyrosine-protein phosphatase eta
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473949.1. On Oct 19, 2010 this sequence version replaced NM_017269.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCCCCGG GGAAGCCCGG GGCGGGCGGA GCGGGGACTA GGCGGACCGG CTGGCGGAGA 
AGGAGGCGGA GGCGTCGGCT GGAGGCGGAG ACCAGGGCGC CCGGCTTCGG GCACACGGCG 
GGGCGCGTCC CGGGCACGTT CCAGGGCGCG CAGGGCATGA AGCCCGCGGC GCGGGAGACG 
CGGACACCCC CGCGCTCGCC CGGGCTCCGC TGGGCGCTGC TGCCGCTGCT GCTGTTGCTA 
CGCCAGGGCC AGGTTGTGTG CGCAGGTGCG GCGCCCAGTC CTGTATTTGA CGTTGAAGCT 
GTCACCAGCC CTACCAGTGT GGTATTAACG TGGAAACACA ATGATTCAGC CACTTCAGAA 
TATAAGATAA ATGAGGGAAA CACGCTGCGG TATACTGTTA AAAACCAGAC ATCATTTAAC 
ATCACAGGCT TAAGCCCAGC TACTTCCTAC AAATTCTCCA TCACCTTGGG AACAGTCAAT 
GAGACCTCAG GAAAGCCCAC ATACAAAAAT ATCACAACAG AGCCCTGGCC AGTGTCGGAT 
CTCCAAGTCG CCTACATCGG TGTGACACAG GCTCTTCTCG CCTGGAGCAA TGCAAACGGC 
ACCGCTTCTT ACCGGATGCA GATTGTAGAG CTGACCACAA ATTCATCAGG TGGTATTTCA 
GATCTGAAGC CGGGGACCCA TAAGAGCTTG GCTGTCCAAG GATCGAATGA GACCCAGCAT 
GACTTATGGG TCACAGAAGG CGTCTCGGAT GCCAATGGCA CCGAGGGAAG CCCAGTGGCC 
AACATATCCC AACTACATAA GAATTCTCTT GCCTCTGCAG ACCCACCCTC TGCCCGGGAT 
CCCTCCCTCA CAGAGGTCTT GCTCACTGAG CTAAAGCCTG ATACTCAGTA CAAAGTCACC 
ATTTATTCTC AAGCAGCAGA TGGCACAGAA GGACAGCCTG GGAACAAAGT GTTTAAAACA 
AATCCCATCC AAGTTTCTGA CATCCGAGCT GTGAACATCA GTGACTCGAA CATGACCCTG 
ACCTGGAAAA GCAACAATAA TGAGTCCCAT GCTTCATTTA CCTACAAAAT ATACGTGGCT 
GGGGGTTCCG ACTCCATCAA CGAAACTGTC AATGAGACTC AGGCCGTCAT CCGTGGACTC 
AGCTCCAGTA CCTTGTACAA CATCACAGTG CTTCCTTTCC TGGGTCAGAC CGCGGGTATA 
CCAGGCTTCC TCCAAGTGTA CACTTCCCCC CGTCCTGTTT CTGACTTCCG AGTGACAAAT 
GTCAGCCTGA GGGAAATCGG TTTGGCTTGG AGAAGCAATG ACTCGGAGTC ATTCGAGATT 
TTCATCACGC AGGAGGGAAG TGAGAAACGT TGGAATGCTT CGACGGGAGA CCTGAGCTAT 
ATCGTTGAAA ATTTAAAGCC TGGGACCAGT TACCAATTTG AAATATTCCC ACGAGGACCA 
AATGGGACTG AAGGGCCATC CCAGACAGTT GTTGGTAGAA CTGACTGCAG TGCTGTGACT 
GACATCCGCG TGGTCAGCGT TAGCACCACT GAAATACAGC TGGAGTGGCA GAATACAGAC 
AGTGCTTCTG GATACACTTA CCATTTAGTT CTAGAGTCTG AGAATGGCTC CATCAAGACC 
AACAGTTCTC AGAAATGGAT CACAGTGGGG GGCCTTACCC CAGGCACCTT ATACAATGTT 
ACAATCTTTC CAGAAGTGGA CCAGATGGAG GGCAACTCCA GCTCTATTAC CCAGTACACA 
AGGCCCAGCA ATGTGTCCTA CATTGAAGTA AACACCAACA CCACCGTGGC AGCCATCCAG 
TGGAAGAACC TGGACGCAGC CTCTGCTTCC TACTCCTACT CCGTTCTTAT CTTGAAGGCT 
GGAGATGGCA GCAATGTAAC CAGCAGGGTC AGAGACATCC CTTCTGTCAC CATCCCTGGG 
CTAATCCCCG GCGTCTCTTA CGAAGTGAAG ATCTTTACAA AGATTAGGAA TACAGAGGTT 
GGGAATGAGG TACCTGGTCA GAAGCTGTTC TGTATGGAAC CTGCACAAGT GGATTCCTTA 
CACTGTGAAG TGGTCCCGAA GGAGCCAGCG CTGGTTCTGA AGTGGGCCTG CCCCCCTGGC 
ATGAACTCAG GCTTTGAACT GGGGGTCAGG AGTGATGCTT GGGACAATAT GACACACTTG 
GAGAACTGCA CTTTGGACAA TGACACAGAG TGCAGGACAG AAGTCACCTA TTTGAATTTT 
TCTACCTCGT ACAACATCAG CATTGCCACC TTGTCATGTG GAAAGATGGC ATTGCCCACC 
CAGAGCACCT GCACCACTGG CATCACAGAC CCACCTCCTC CAGATGGATC CCCTAATATT 
ACATCGGTCA GTCACAATTC AGTAAAGGTG AAGTTCAGTG GTTTTGAAGC CAGCCATGGA 
CCTATCAAAG CCTATGCTGT CCTTCTCACC ACAGGGGAAG CTGGCCAACC CTCCACAGAT 
GTTTTGAAGT ACACATATGA AGATTTCAAA AAGGGAGCCT CCGATACTTA TGTGACATAC 
CTCATAAGGA TAGAAGAGAA GGGACAGTCT CAGGGCTTGT CTGAAGCATT GAACTATGAG 
ATTGATGTGG GGAACCAATC CACTACCCTC GGCTACTACA ACGGGAGGCT AGAGCCTCTG 
GGCTCCTACC GGGCTTGCGT TGCTGGCTTT ACCAATATTA CCTACAACCT TCAGAACGAT 
GGCCTTATTA ATGGGGATGA GAGCTATGTA TCTTTCAGTC CGTATTCAGA GGCCGTGTCC 
TTGCCTCAAG ATCCAGGTGT CATCTGCGGA GCGGTGTTCG GATGTATCTT TGGTGCCCTG 
GCCATTGTGG CTGTGGGAGG CTTCATCTTC TGGAGAAAGA AAAGGAAAGA TGCCAAGAAT 
AATGAAGTGT CCTTTTCTCA AATTAAATCC AAGTTAATCC GAGTGGAGAA TTTTGAGGCC 
TACTTTAAGA AACAGCAAGC CGACTCCAAC TGTGGGTTTG CAGAGGAATA TGAGGATCTG 
AAGCTGATTG GAATAAGTTT ACCTAAATAT GCAGCGGAAA TAGCTGAAAA CAGGGGGAAG 
AACCGCTACA ACAACGTCCT GCCCTATGAT ATTTCTCGAG TCAAACTTTC AGTCCAGACC 
CATTCGACAG ACGACTACAT CAATGCCAAC TATATGCCTG GCTACCATTC CAAGAAAGAT 
TTCATTGCCA CACAAGGACC TTTACCCAAC ACTTTGAAAG ATTTTTGGCG TATGGTTTGG 
GAGAAAAACG TATATGCCAT TGTTATGCTG ACCAAATGTG TGGAGCAGGG AAGGACCAAA 
TGTGAAGAGT ACTGGCCTTC CAAGCAGGCT CAGGACTACG GGGACATAAC TGTGGCAATG 
ACATCAGAAG TTGTTCTTCC GGAATGGACC ATCAGAGATT TTGTGGTGAA AAATATGCAG 
AGTAGTGAGA GTCATCCTCT GCGGCAGTTC CATTTCACCT CCTGGCCTGA CCATGGTGTT 
CCTGACACCA CCGACCTGCT CATCAACTTT CGGTACCTGG TCCGGGATTA CATGAAGCAG 
ATCCCCCCTG AGTCACCAAT CCTGGTGCAT TGCAGTGCTG GGGTTGGAAG GACGGGCACT 
TTCATTGCTA TTGATCGCCT GATCTATCAG ATAGAGAACG AGAACACCGT GGATGTGTAT 
GGCATTGTCT ACGATCTTCG GATGCACAGG CCTCTGATGG TACAGACAGA GGACCAGTAT 
GTTTTCCTCA ATCAGTGTGT GTTGGATATT ATCAGAGCCC AGAAAGACTC AAAAGTTGAC 
CTCATCTATC AGAACACAAC CGCAATGACA ATCTATGAAA ACCTCGAGCC AGTGAGCATG 
TTTGGAAAGA CTAATGGTTA CATCGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058965.2
CDS	61..3930
Translation	MSPGKPGAGGAGTRRTGWRRRRRRRRLEAETRAPGFGHTAGRVPGTFQGAQGMKPAARETRTPPRSPGLRWALLPLLLLLRQGQVVCAGAAPSPVFDVEAVTSPTSVVLTWKHNDSATSEYKINEGNTLRYTVKNQTSFNITGLSPATSYKFSITLGTVNETSGKPTYKNITTEPWPVSDLQVAYIGVTQALLAWSNANGTASYRMQIVELTTNSSGGISDLKPGTHKSLAVQGSNETQHDLWVTEGVSDANGTEGSPVANISQLHKNSLASADPPSARDPSLTEVLLTELKPDTQYKVTIYSQAADGTEGQPGNKVFKTNPIQVSDIRAVNISDSNMTLTWKSNNNESHASFTYKIYVAGGSDSINETVNETQAVIRGLSSSTLYNITVLPFLGQTAGIPGFLQVYTSPRPVSDFRVTNVSLREIGLAWRSNDSESFEIFITQEGSEKRWNASTGDLSYIVENLKPGTSYQFEIFPRGPNGTEGPSQTVVGRTDCSAVTDIRVVSVSTTEIQLEWQNTDSASGYTYHLVLESENGSIKTNSSQKWITVGGLTPGTLYNVTIFPEVDQMEGNSSSITQYTRPSNVSYIEVNTNTTVAAIQWKNLDAASASYSYSVLILKAGDGSNVTSRVRDIPSVTIPGLIPGVSYEVKIFTKIRNTEVGNEVPGQKLFCMEPAQVDSLHCEVVPKEPALVLKWACPPGMNSGFELGVRSDAWDNMTHLENCTLDNDTECRTEVTYLNFSTSYNISIATLSCGKMALPTQSTCTTGITDPPPPDGSPNITSVSHNSVKVKFSGFEASHGPIKAYAVLLTTGEAGQPSTDVLKYTYEDFKKGASDTYVTYLIRIEEKGQSQGLSEALNYEIDVGNQSTTLGYYNGRLEPLGSYRACVAGFTNITYNLQNDGLINGDESYVSFSPYSEAVSLPQDPGVICGAVFGCIFGALAIVAVGGFIFWRKKRKDAKNNEVSFSQIKSKLIRVENFEAYFKKQQADSNCGFAEEYEDLKLIGISLPKYAAEIAENRGKNRYNNVLPYDISRVKLSVQTHSTDDYINANYMPGYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIVMLTKCVEQGRTKCEEYWPSKQAQDYGDITVAMTSEVVLPEWTIRDFVVKNMQSSESHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIIRAQKDSKVDLIYQNTTAMTIYENLEPVSMFGKTNGYIA

Target ORF information:

RefSeq Version	NM_017269.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus protein tyrosine phosphatase, receptor type, J (Ptprj), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017269.2

ORF Insert Sequence:

ATGTCCCCGG GGAAGCCCGG GGCGGGCGGA GCGGGGACTA GGCGGACCGG CTGGCGGAGA 
AGGAGGCGGA GGCGTCGGCT GGAGGCGGAG ACCAGGGCGC CCGGCTTCGG GCACACGGCG 
GGGCGCGTCC CGGGCACGTT CCAGGGCGCG CAGGGCATGA AGCCCGCGGC GCGGGAGACG 
CGGACACCCC CGCGCTCGCC CGGGCTCCGC TGGGCGCTGC TGCCGCTGCT GCTGTTGCTA 
CGCCAGGGCC AGGTTGTGTG CGCAGGTGCG GCGCCCAGTC CTGTATTTGA CGTTGAAGCT 
GTCACCAGCC CTACCAGTGT GGTATTAACG TGGAAACACA ATGATTCAGC CACTTCAGAA 
TATAAGATAA ATGAGGGAAA CACGCTGCGG TATACTGTTA AAAACCAGAC ATCATTTAAC 
ATCACAGGCT TAAGCCCAGC TACTTCCTAC AAATTCTCCA TCACCTTGGG AACAGTCAAT 
GAGACCTCAG GAAAGCCCAC ATACAAAAAT ATCACAACAG AGCCCTGGCC AGTGTCGGAT 
CTCCAAGTCG CCTACATCGG TGTGACACAG GCTCTTCTCG CCTGGAGCAA TGCAAACGGC 
ACCGCTTCTT ACCGGATGCA GATTGTAGAG CTGACCACAA ATTCATCAGG TGGTATTTCA 
GATCTGAAGC CGGGGACCCA TAAGAGCTTG GCTGTCCAAG GATCGAATGA GACCCAGCAT 
GACTTATGGG TCACAGAAGG CGTCTCGGAT GCCAATGGCA CCGAGGGAAG CCCAGTGGCC 
AACATATCCC AACTACATAA GAATTCTCTT GCCTCTGCAG ACCCACCCTC TGCCCGGGAT 
CCCTCCCTCA CAGAGGTCTT GCTCACTGAG CTAAAGCCTG ATACTCAGTA CAAAGTCACC 
ATTTATTCTC AAGCAGCAGA TGGCACAGAA GGACAGCCTG GGAACAAAGT GTTTAAAACA 
AATCCCATCC AAGTTTCTGA CATCCGAGCT GTGAACATCA GTGACTCGAA CATGACCCTG 
ACCTGGAAAA GCAACAATAA TGAGTCCCAT GCTTCATTTA CCTACAAAAT ATACGTGGCT 
GGGGGTTCCG ACTCCATCAA CGAAACTGTC AATGAGACTC AGGCCGTCAT CCGTGGACTC 
AGCTCCAGTA CCTTGTACAA CATCACAGTG CTTCCTTTCC TGGGTCAGAC CGCGGGTATA 
CCAGGCTTCC TCCAAGTGTA CACTTCCCCC CGTCCTGTTT CTGACTTCCG AGTGACAAAT 
GTCAGCCTGA GGGAAATCGG TTTGGCTTGG AGAAGCAATG ACTCGGAGTC ATTCGAGATT 
TTCATCACGC AGGAGGGAAG TGAGAAACGT TGGAATGCTT CGACGGGAGA CCTGAGCTAT 
ATCGTTGAAA ATTTAAAGCC TGGGACCAGT TACCAATTTG AAATATTCCC ACGAGGACCA 
AATGGGACTG AAGGGCCATC CCAGACAGTT GTTGGTAGAA CTGACTGCAG TGCTGTGACT 
GACATCCGCG TGGTCAGCGT TAGCACCACT GAAATACAGC TGGAGTGGCA GAATACAGAC 
AGTGCTTCTG GATACACTTA CCATTTAGTT CTAGAGTCTG AGAATGGCTC CATCAAGACC 
AACAGTTCTC AGAAATGGAT CACAGTGGGG GGCCTTACCC CAGGCACCTT ATACAATGTT 
ACAATCTTTC CAGAAGTGGA CCAGATGGAG GGCAACTCCA GCTCTATTAC CCAGTACACA 
AGGCCCAGCA ATGTGTCCTA CATTGAAGTA AACACCAACA CCACCGTGGC AGCCATCCAG 
TGGAAGAACC TGGACGCAGC CTCTGCTTCC TACTCCTACT CCGTTCTTAT CTTGAAGGCT 
GGAGATGGCA GCAATGTAAC CAGCAGGGTC AGAGACATCC CTTCTGTCAC CATCCCTGGG 
CTAATCCCCG GCGTCTCTTA CGAAGTGAAG ATCTTTACAA AGATTAGGAA TACAGAGGTT 
GGGAATGAGG TACCTGGTCA GAAGCTGTTC TGTATGGAAC CTGCACAAGT GGATTCCTTA 
CACTGTGAAG TGGTCCCGAA GGAGCCAGCG CTGGTTCTGA AGTGGGCCTG CCCCCCTGGC 
ATGAACTCAG GCTTTGAACT GGGGGTCAGG AGTGATGCTT GGGACAATAT GACACACTTG 
GAGAACTGCA CTTTGGACAA TGACACAGAG TGCAGGACAG AAGTCACCTA TTTGAATTTT 
TCTACCTCGT ACAACATCAG CATTGCCACC TTGTCATGTG GAAAGATGGC ATTGCCCACC 
CAGAGCACCT GCACCACTGG CATCACAGAC CCACCTCCTC CAGATGGATC CCCTAATATT 
ACATCGGTCA GTCACAATTC AGTAAAGGTG AAGTTCAGTG GTTTTGAAGC CAGCCATGGA 
CCTATCAAAG CCTATGCTGT CCTTCTCACC ACAGGGGAAG CTGGCCAACC CTCCACAGAT 
GTTTTGAAGT ACACATATGA AGATTTCAAA AAGGGAGCCT CCGATACTTA TGTGACATAC 
CTCATAAGGA TAGAAGAGAA GGGACAGTCT CAGGGCTTGT CTGAAGCATT GAACTATGAG 
ATTGATGTGG GGAACCAATC CACTACCCTC GGCTACTACA ACGGGAGGCT AGAGCCTCTG 
GGCTCCTACC GGGCTTGCGT TGCTGGCTTT ACCAATATTA CCTACAACCT TCAGAACGAT 
GGCCTTATTA ATGGGGATGA GAGCTATGTA TCTTTCAGTC CGTATTCAGA GGCCGTGTCC 
TTGCCTCAAG ATCCAGGTGT CATCTGCGGA GCGGTGTTCG GATGTATCTT TGGTGCCCTG 
GCCATTGTGG CTGTGGGAGG CTTCATCTTC TGGAGAAAGA AAAGGAAAGA TGCCAAGAAT 
AATGAAGTGT CCTTTTCTCA AATTAAATCC AAGTTAATCC GAGTGGAGAA TTTTGAGGCC 
TACTTTAAGA AACAGCAAGC CGACTCCAAC TGTGGGTTTG CAGAGGAATA TGAGGATCTG 
AAGCTGATTG GAATAAGTTT ACCTAAATAT GCAGCGGAAA TAGCTGAAAA CAGGGGGAAG 
AACCGCTACA ACAACGTCCT GCCCTATGAT ATTTCTCGAG TCAAACTTTC AGTCCAGACC 
CATTCGACAG ACGACTACAT CAATGCCAAC TATATGCCTG GCTACCATTC CAAGAAAGAT 
TTCATTGCCA CACAAGGACC TTTACCCAAC ACTTTGAAAG ATTTTTGGCG TATGGTTTGG 
GAGAAAAACG TATATGCCAT TGTTATGCTG ACCAAATGTG TGGAGCAGGG AAGGACCAAA 
TGTGAAGAGT ACTGGCCTTC CAAGCAGGCT CAGGACTACG GGGACATAAC TGTGGCAATG 
ACATCAGAAG TTGTTCTTCC GGAATGGACC ATCAGAGATT TTGTGGTGAA AAATATGCAG 
AGTAGTGAGA GTCATCCTCT GCGGCAGTTC CATTTCACCT CCTGGCCTGA CCATGGTGTT 
CCTGACACCA CCGACCTGCT CATCAACTTT CGGTACCTGG TCCGGGATTA CATGAAGCAG 
ATCCCCCCTG AGTCACCAAT CCTGGTGCAT TGCAGTGCTG GGGTTGGAAG GACGGGCACT 
TTCATTGCTA TTGATCGCCT GATCTATCAG ATAGAGAACG AGAACACCGT GGATGTGTAT 
GGCATTGTCT ACGATCTTCG GATGCACAGG CCTCTGATGG TACAGACAGA GGACCAGTAT 
GTTTTCCTCA ATCAGTGTGT GTTGGATATT ATCAGAGCCC AGAAAGACTC AAAAGTTGAC 
CTCATCTATC AGAACACAAC CGCAATGACA ATCTATGAAA ACCTCGAGCC AGTGAGCATG 
TTTGGAAAGA CTAATGGTTA CATCGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Defining the molecular basis of interaction between R3 receptor-type protein tyrosine phosphatases and VE-cadherin.
PloS one12(9)e0184574(2017)
Dorofejeva O,Barr AJ

Loss of the protein-tyrosine phosphatase DEP-1/PTPRJ drives meningioma cell motility.
Brain pathology (Zurich, Switzerland)21(4)405-18(2011 Jul)
Petermann A,Haase D,Wetzel A,Balavenkatraman KK,Tenev T,G?hrs KH,Friedrich S,Nakamura M,Mawrin C,B?hmer FD

Phosphatome profiling reveals PTPN2, PTPRJ and PTEN as potent negative regulators of PKB/Akt activation in Ras-mutated cancer cells.
The Biochemical journal426(1)65-72(2010 Jan)
Omerovic J,Clague MJ,Prior IA

An unbiased screen identifies DEP-1 tumor suppressor as a phosphatase controlling EGFR endocytosis.
Current biology : CB19(21)1788-98(2009 Nov)
Tarcic G,Boguslavsky SK,Wakim J,Kiuchi T,Liu A,Reinitz F,Nathanson D,Takahashi T,Mischel PS,Ng T,Yarden Y

Tumor suppressor density-enhanced phosphatase-1 (DEP-1) inhibits the RAS pathway by direct dephosphorylation of ERK1/2 kinases.
The Journal of biological chemistry284(33)22048-58(2009 Aug)
Sacco F,Tinti M,Palma A,Ferrari E,Nardozza AP,Hooft van Huijsduijnen R,Takahashi T,Castagnoli L,Cesareni G

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Ptprj cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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