Pak6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pak6
Entrez Gene ID	296078
Full Name	p21 (RAC1) activated kinase 6
General protein information	Preferred Names p21 (RAC1) activated kinase 6 Names serine/threonine-protein kinase PAK 6 p21 (CDKN1A)-activated kinase 6 p21 protein (Cdc42/Rac)-activated kinase 6 p21-activated kinase 6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q35

mRNA and Protein(s)

mRNA	Protein	Name
XM_017591575.1	XP_017447064.1	serine/threonine-protein kinase PAK 6 isoform X1
NM_001106498.1	NP_001099968.1	serine/threonine-protein kinase PAK 6

Pathways from BioSystems

Homologies

	PAK6	XP_001094298.1
Bos taurus (cattle)	PAK6	NP_001179127.1
Homo sapiens (human)	PAK6	NP_001263646.1
Canis lupus familiaris (dog)	PAK6	XP_003640077.1
Xenopus tropicalis (tropical clawed frog)	pak6	XP_002932872.2
Mus musculus (house mouse)	Pak6	NP_001028426.2
Gallus gallus (chicken)	PAK6	XP_426393.3
Danio rerio (zebrafish)	pak6b	NP_001155959.1
Danio rerio (zebrafish)	LOC100536197	XP_003200338.1
Pan troglodytes (chimpanzee)	PAK6	XP_510302.2
Rattus norvegicus (Norway rat)	Pak6	NP_001099968.1

Gene Ontology
Bibliography

Related articles in PubMed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)

Prognostic significance of p21-activated kinase 6 expression in patients with clear cell renal cell carcinoma.
Liu W, Liu H, Liu Y, Xu L, Zhang W, Zhu Y, Xu J, Gu J
Annals of surgical oncology21 Suppl 4S575-83(2014 Dec)

Functional deficits in PAK5, PAK6 and PAK5/PAK6 knockout mice.
Furnari MA, Jobes ML, Nekrasova T, Minden A, Wagner GC
PloS one8(4)e61321(2013)

Upregulation of p21-activated Kinase 6 in rat brain cortex after traumatic brain injury.
Zhao W, Yang J, Shi W, Wu X, Shao B, Wu Q, Chen J, Ni L
Journal of molecular histology42(3)195-203(2011 Jun)

Targeted disruption of the Pak5 and Pak6 genes in mice leads to deficits in learning and locomotion.
Nekrasova T, Jobes ML, Ting JH, Wagner GC, Minden A
Developmental biology322(1)95-108(2008 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

after injury, the expression of PAK6 was increased significantly in the astrocytes and neurons
Title: Upregulation of p21-activated Kinase 6 in rat brain cortex after traumatic brain injury.

The following Pak6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pak6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa41418	NM_001106498.1 Latest version!	Rattus norvegicus p21 (RAC1) activated kinase 6 (Pak6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa41418	XM_017591575.1 Latest version!	Rattus norvegicus p21 (RAC1) activated kinase 6 (Pak6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pak6 ( NM_001106498.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099968.1 Rattus norvegicus p21 (RAC1) activated kinase 6 (Pak6), mRNA.

Price & Availability↑

CloneID	ORa41418
Clone ID Related Accession (Same CDS sequence)	XM_017591575.1 , NM_001106498.1
Accession Version	NM_001106498.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2046bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein kinase PAK 6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473949.1. On or before Oct 4, 2007 this sequence version replaced XM_001080745.1, XM_230519.4. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTTCCGAA AGAAGAAGAA GAAACGCCCT GAGATATCAG CCCCACAGAA CTTCCAGCAC 
CGTGTTCACA CCTCATTTGA CCCCAAGGAA GGCAAGTTCG TGGGCCTGCC CCCACAATGG 
CAGAACATCC TGGATACTCT GAGGCGGCCC AAGCCTGTGG TGGATCCTTC TCGAATCACA 
CGGGTGCAGT TGCAGCCCAT GAAGACGGTA GTACGGGGCA GCTCAGTGCC CACAGAGGGC 
TACATCTCCG GGCTGCTCAA TGACATTCAG AAGTTGTCAG CTATCAGCTC CAACACTCTG 
CGTGGACGCA GCCCCACCAG CCGGCGGCGG GCACAGTCCC TGGGGCTGCT AGGAGATGAT 
CAGTGGGCGG CTGACCCGGA TATGTACCTC CAAAGTCCTC AGTCTGAGCG CACTGATCCC 
CATGGCGTCT ACCTCAGCTG TAATGGGGGC ACACCAGCAG GTCACAGGCA AACGCCATGG 
CCAGAACCAC AGAGCCCACA GGCCCTGCCC AATGGCATGG CTGCCAAGGC ACAGTCGCTG 
GGCCCCGCTG AGTTCCAGGG TGCCTCCCAA CGCTGCCTGC AGCTGGGTGC CTGCCTACAG 
AGTTCCCCAC CTGGTACCTC ACCCCCTATG GCCACAGGGA GGCGTGGGGT GAAGGTTACC 
AAGCATAGCT CGGAAGAGGC TCGACCACAA TCTTGCCTGG TGGGCTCAGC CATTGGCAGA 
CCAGGTGGAG AAGGCAGCCC CAGCCCTAAG ACCCAGGAAA GCAGCCTCAA GCACCGGCTC 
TTCCGCAGCA TGTTCCTGTC CACTCCCGCC ACAGGCTCTG CAAGCAGCAG CAAGCCGGTC 
CCTCTGCCAC AGAACAAGCT CAATTCTGCT TTCCGACCAC CACAAAAAGA TTCCTCTTCA 
AACCTGGTAG CCAAGGCCCA GTCCTTGCCC TCAGATCAGC CCACGGGGAC CTTCAGTCCT 
CTGACCACCT CAGATACCAG CAGTCCCCAG AAGTCCCTCC GCACAGCCCC AGCCACTGGT 
CCACTTCCAG GCCGGTCTTC TCCAGCAGGC TCCCCCCGCA CCCGGCATGC CCAGATCAGC 
ACCAGCAATC TATACCTGCC CCAGGACCCC ACAGTGGCCA AGGGGGCCCT GGGTGGCGAA 
GACACAGGCA TCGTAACACA TGAGCAGTTC AAAGCTGCGC TCAGGATGGT GGTGGACCAG 
GGTGACCCTC GGCTGCTGCT GGACAGCTAT GTGAAGATTG GGGAGGGCTC CACGGGCATT 
GTGTGTCTGG CCCGGGAGAA GCATTCAGGT CGCCAGGTAG CAGTCAAGAT GATGGACCTC 
AGAAAGCAGC AACGCAGGGA ACTGCTCTTT AATGAGGTGG TGATCATGCG TGACTACCAG 
CACCTCAATG TGGTGGAGAT GTACAAGAGT TACCTGGTAG GAGAGGAGCT GTGGGTGCTG 
ATGGAGTTCC TGCAGGGCGG GGCCCTCACA GACATCATCT CCCAAGTCAG ACTCAATGAG 
GAACAGATTG CTACTGTGTG TGAAGCTGTG CTTCAGGCCT TGGCTTACCT GCACGCCCAG 
GGTGTCATCC ACCGAGACAT CAAGAGTGAT TCCATCCTGC TGACCCTTGA TGGCAGGGTG 
AAGCTCTCAG ACTTTGGGTT CTGTGCTCAG ATCAGCAAAG ATGTCCCCAA GAGAAAGTCT 
CTCGTAGGAA CTCCATACTG GATGGCTCCT GAGGTGATCT CCAGATCCCT GTACGCTACT 
GAGGTGGATA TCTGGTCTCT GGGCATCATG GTGATTGAGA TGGTGGATGG AGAACCCCCT 
TACTTCAGCG ACTCCCCAGT GCAAGCCATG AAGAGGCTCC GGGACAGCCC CCCACCCAAG 
CTAAAGAACT CTTACAAGGT CTCTCCAGTG CTGCGAGACT TCCTGGAACG AATGCTGGTA 
CGGGAACCCC AAGAGAGAGC CACAGCCCAG GAGCTCCTGG ATCACCCCTT TCTGCTGCAG 
ACGGGGCTGC CCGAGTGTCT GGTGCCTCTG ATACAGCTCT ACCGCAAGCA GACCTCCACC 
TGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099968.1
CDS	637..2682
Translation	MFRKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDTLRRPKPVVDPSRITRVQLQPMKTVVRGSSVPTEGYISGLLNDIQKLSAISSNTLRGRSPTSRRRAQSLGLLGDDQWAADPDMYLQSPQSERTDPHGVYLSCNGGTPAGHRQTPWPEPQSPQALPNGMAAKAQSLGPAEFQGASQRCLQLGACLQSSPPGTSPPMATGRRGVKVTKHSSEEARPQSCLVGSAIGRPGGEGSPSPKTQESSLKHRLFRSMFLSTPATGSASSSKPVPLPQNKLNSAFRPPQKDSSSNLVAKAQSLPSDQPTGTFSPLTTSDTSSPQKSLRTAPATGPLPGRSSPAGSPRTRHAQISTSNLYLPQDPTVAKGALGGEDTGIVTHEQFKAALRMVVDQGDPRLLLDSYVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHLNVVEMYKSYLVGEELWVLMEFLQGGALTDIISQVRLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSYKVSPVLRDFLERMLVREPQERATAQELLDHPFLLQTGLPECLVPLIQLYRKQTSTC

Target ORF information:

RefSeq Version	NM_001106498.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus p21 (RAC1) activated kinase 6 (Pak6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106498.1

ORF Insert Sequence:

ATGTTCCGAA AGAAGAAGAA GAAACGCCCT GAGATATCAG CCCCACAGAA CTTCCAGCAC 
CGTGTTCACA CCTCATTTGA CCCCAAGGAA GGCAAGTTCG TGGGCCTGCC CCCACAATGG 
CAGAACATCC TGGATACTCT GAGGCGGCCC AAGCCTGTGG TGGATCCTTC TCGAATCACA 
CGGGTGCAGT TGCAGCCCAT GAAGACGGTA GTACGGGGCA GCTCAGTGCC CACAGAGGGC 
TACATCTCCG GGCTGCTCAA TGACATTCAG AAGTTGTCAG CTATCAGCTC CAACACTCTG 
CGTGGACGCA GCCCCACCAG CCGGCGGCGG GCACAGTCCC TGGGGCTGCT AGGAGATGAT 
CAGTGGGCGG CTGACCCGGA TATGTACCTC CAAAGTCCTC AGTCTGAGCG CACTGATCCC 
CATGGCGTCT ACCTCAGCTG TAATGGGGGC ACACCAGCAG GTCACAGGCA AACGCCATGG 
CCAGAACCAC AGAGCCCACA GGCCCTGCCC AATGGCATGG CTGCCAAGGC ACAGTCGCTG 
GGCCCCGCTG AGTTCCAGGG TGCCTCCCAA CGCTGCCTGC AGCTGGGTGC CTGCCTACAG 
AGTTCCCCAC CTGGTACCTC ACCCCCTATG GCCACAGGGA GGCGTGGGGT GAAGGTTACC 
AAGCATAGCT CGGAAGAGGC TCGACCACAA TCTTGCCTGG TGGGCTCAGC CATTGGCAGA 
CCAGGTGGAG AAGGCAGCCC CAGCCCTAAG ACCCAGGAAA GCAGCCTCAA GCACCGGCTC 
TTCCGCAGCA TGTTCCTGTC CACTCCCGCC ACAGGCTCTG CAAGCAGCAG CAAGCCGGTC 
CCTCTGCCAC AGAACAAGCT CAATTCTGCT TTCCGACCAC CACAAAAAGA TTCCTCTTCA 
AACCTGGTAG CCAAGGCCCA GTCCTTGCCC TCAGATCAGC CCACGGGGAC CTTCAGTCCT 
CTGACCACCT CAGATACCAG CAGTCCCCAG AAGTCCCTCC GCACAGCCCC AGCCACTGGT 
CCACTTCCAG GCCGGTCTTC TCCAGCAGGC TCCCCCCGCA CCCGGCATGC CCAGATCAGC 
ACCAGCAATC TATACCTGCC CCAGGACCCC ACAGTGGCCA AGGGGGCCCT GGGTGGCGAA 
GACACAGGCA TCGTAACACA TGAGCAGTTC AAAGCTGCGC TCAGGATGGT GGTGGACCAG 
GGTGACCCTC GGCTGCTGCT GGACAGCTAT GTGAAGATTG GGGAGGGCTC CACGGGCATT 
GTGTGTCTGG CCCGGGAGAA GCATTCAGGT CGCCAGGTAG CAGTCAAGAT GATGGACCTC 
AGAAAGCAGC AACGCAGGGA ACTGCTCTTT AATGAGGTGG TGATCATGCG TGACTACCAG 
CACCTCAATG TGGTGGAGAT GTACAAGAGT TACCTGGTAG GAGAGGAGCT GTGGGTGCTG 
ATGGAGTTCC TGCAGGGCGG GGCCCTCACA GACATCATCT CCCAAGTCAG ACTCAATGAG 
GAACAGATTG CTACTGTGTG TGAAGCTGTG CTTCAGGCCT TGGCTTACCT GCACGCCCAG 
GGTGTCATCC ACCGAGACAT CAAGAGTGAT TCCATCCTGC TGACCCTTGA TGGCAGGGTG 
AAGCTCTCAG ACTTTGGGTT CTGTGCTCAG ATCAGCAAAG ATGTCCCCAA GAGAAAGTCT 
CTCGTAGGAA CTCCATACTG GATGGCTCCT GAGGTGATCT CCAGATCCCT GTACGCTACT 
GAGGTGGATA TCTGGTCTCT GGGCATCATG GTGATTGAGA TGGTGGATGG AGAACCCCCT 
TACTTCAGCG ACTCCCCAGT GCAAGCCATG AAGAGGCTCC GGGACAGCCC CCCACCCAAG 
CTAAAGAACT CTTACAAGGT CTCTCCAGTG CTGCGAGACT TCCTGGAACG AATGCTGGTA 
CGGGAACCCC AAGAGAGAGC CACAGCCCAG GAGCTCCTGG ATCACCCCTT TCTGCTGCAG 
ACGGGGCTGC CCGAGTGTCT GGTGCCTCTG ATACAGCTCT ACCGCAAGCA GACCTCCACC 
TGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pak6 ( XM_017591575.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447064.1 Rattus norvegicus p21 (RAC1) activated kinase 6 (Pak6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa41418
Clone ID Related Accession (Same CDS sequence)	XM_017591575.1 , NM_001106498.1
Accession Version	XM_017591575.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2046bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein kinase PAK 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) and transcript sequence (NM_001106498.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases assembly gap :: added 79 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END##

ATGTTCCGAA AGAAGAAGAA GAAACGCCCT GAGATATCAG CCCCACAGAA CTTCCAGCAC 
CGTGTTCACA CCTCATTTGA CCCCAAGGAA GGCAAGTTCG TGGGCCTGCC CCCACAATGG 
CAGAACATCC TGGATACTCT GAGGCGGCCC AAGCCTGTGG TGGATCCTTC TCGAATCACA 
CGGGTGCAGT TGCAGCCCAT GAAGACGGTA GTACGGGGCA GCTCAGTGCC CACAGAGGGC 
TACATCTCCG GGCTGCTCAA TGACATTCAG AAGTTGTCAG CTATCAGCTC CAACACTCTG 
CGTGGACGCA GCCCCACCAG CCGGCGGCGG GCACAGTCCC TGGGGCTGCT AGGAGATGAT 
CAGTGGGCGG CTGACCCGGA TATGTACCTC CAAAGTCCTC AGTCTGAGCG CACTGATCCC 
CATGGCGTCT ACCTCAGCTG TAATGGGGGC ACACCAGCAG GTCACAGGCA AACGCCATGG 
CCAGAACCAC AGAGCCCACA GGCCCTGCCC AATGGCATGG CTGCCAAGGC ACAGTCGCTG 
GGCCCCGCTG AGTTCCAGGG TGCCTCCCAA CGCTGCCTGC AGCTGGGTGC CTGCCTACAG 
AGTTCCCCAC CTGGTACCTC ACCCCCTATG GCCACAGGGA GGCGTGGGGT GAAGGTTACC 
AAGCATAGCT CGGAAGAGGC TCGACCACAA TCTTGCCTGG TGGGCTCAGC CATTGGCAGA 
CCAGGTGGAG AAGGCAGCCC CAGCCCTAAG ACCCAGGAAA GCAGCCTCAA GCACCGGCTC 
TTCCGCAGCA TGTTCCTGTC CACTCCCGCC ACAGGCTCTG CAAGCAGCAG CAAGCCGGTC 
CCTCTGCCAC AGAACAAGCT CAATTCTGCT TTCCGACCAC CACAAAAAGA TTCCTCTTCA 
AACCTGGTAG CCAAGGCCCA GTCCTTGCCC TCAGATCAGC CCACGGGGAC CTTCAGTCCT 
CTGACCACCT CAGATACCAG CAGTCCCCAG AAGTCCCTCC GCACAGCCCC AGCCACTGGT 
CCACTTCCAG GCCGGTCTTC TCCAGCAGGC TCCCCCCGCA CCCGGCATGC CCAGATCAGC 
ACCAGCAATC TATACCTGCC CCAGGACCCC ACAGTGGCCA AGGGGGCCCT GGGTGGCGAA 
GACACAGGCA TCGTAACACA TGAGCAGTTC AAAGCTGCGC TCAGGATGGT GGTGGACCAG 
GGTGACCCTC GGCTGCTGCT GGACAGCTAT GTGAAGATTG GGGAGGGCTC CACGGGCATT 
GTGTGTCTGG CCCGGGAGAA GCATTCAGGT CGCCAGGTAG CAGTCAAGAT GATGGACCTC 
AGAAAGCAGC AACGCAGGGA ACTGCTCTTT AATGAGGTGG TGATCATGCG TGACTACCAG 
CACCTCAATG TGGTGGAGAT GTACAAGAGT TACCTGGTAG GAGAGGAGCT GTGGGTGCTG 
ATGGAGTTCC TGCAGGGCGG GGCCCTCACA GACATCATCT CCCAAGTCAG ACTCAATGAG 
GAACAGATTG CTACTGTGTG TGAAGCTGTG CTTCAGGCCT TGGCTTACCT GCACGCCCAG 
GGTGTCATCC ACCGAGACAT CAAGAGTGAT TCCATCCTGC TGACCCTTGA TGGCAGGGTG 
AAGCTCTCAG ACTTTGGGTT CTGTGCTCAG ATCAGCAAAG ATGTCCCCAA GAGAAAGTCT 
CTCGTAGGAA CTCCATACTG GATGGCTCCT GAGGTGATCT CCAGATCCCT GTACGCTACT 
GAGGTGGATA TCTGGTCTCT GGGCATCATG GTGATTGAGA TGGTGGATGG AGAACCCCCT 
TACTTCAGCG ACTCCCCAGT GCAAGCCATG AAGAGGCTCC GGGACAGCCC CCCACCCAAG 
CTAAAGAACT CTTACAAGGT CTCTCCAGTG CTGCGAGACT TCCTGGAACG AATGCTGGTA 
CGGGAACCCC AAGAGAGAGC CACAGCCCAG GAGCTCCTGG ATCACCCCTT TCTGCTGCAG 
ACGGGGCTGC CCGAGTGTCT GGTGCCTCTG ATACAGCTCT ACCGCAAGCA GACCTCCACC 
TGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447064.1
CDS	1099..3144
Translation	MFRKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDTLRRPKPVVDPSRITRVQLQPMKTVVRGSSVPTEGYISGLLNDIQKLSAISSNTLRGRSPTSRRRAQSLGLLGDDQWAADPDMYLQSPQSERTDPHGVYLSCNGGTPAGHRQTPWPEPQSPQALPNGMAAKAQSLGPAEFQGASQRCLQLGACLQSSPPGTSPPMATGRRGVKVTKHSSEEARPQSCLVGSAIGRPGGEGSPSPKTQESSLKHRLFRSMFLSTPATGSASSSKPVPLPQNKLNSAFRPPQKDSSSNLVAKAQSLPSDQPTGTFSPLTTSDTSSPQKSLRTAPATGPLPGRSSPAGSPRTRHAQISTSNLYLPQDPTVAKGALGGEDTGIVTHEQFKAALRMVVDQGDPRLLLDSYVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHLNVVEMYKSYLVGEELWVLMEFLQGGALTDIISQVRLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSYKVSPVLRDFLERMLVREPQERATAQELLDHPFLLQTGLPECLVPLIQLYRKQTSTC

Target ORF information:

RefSeq Version	XM_017591575.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus p21 (RAC1) activated kinase 6 (Pak6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017591575.1

ORF Insert Sequence:

ATGTTCCGAA AGAAGAAGAA GAAACGCCCT GAGATATCAG CCCCACAGAA CTTCCAGCAC 
CGTGTTCACA CCTCATTTGA CCCCAAGGAA GGCAAGTTCG TGGGCCTGCC CCCACAATGG 
CAGAACATCC TGGATACTCT GAGGCGGCCC AAGCCTGTGG TGGATCCTTC TCGAATCACA 
CGGGTGCAGT TGCAGCCCAT GAAGACGGTA GTACGGGGCA GCTCAGTGCC CACAGAGGGC 
TACATCTCCG GGCTGCTCAA TGACATTCAG AAGTTGTCAG CTATCAGCTC CAACACTCTG 
CGTGGACGCA GCCCCACCAG CCGGCGGCGG GCACAGTCCC TGGGGCTGCT AGGAGATGAT 
CAGTGGGCGG CTGACCCGGA TATGTACCTC CAAAGTCCTC AGTCTGAGCG CACTGATCCC 
CATGGCGTCT ACCTCAGCTG TAATGGGGGC ACACCAGCAG GTCACAGGCA AACGCCATGG 
CCAGAACCAC AGAGCCCACA GGCCCTGCCC AATGGCATGG CTGCCAAGGC ACAGTCGCTG 
GGCCCCGCTG AGTTCCAGGG TGCCTCCCAA CGCTGCCTGC AGCTGGGTGC CTGCCTACAG 
AGTTCCCCAC CTGGTACCTC ACCCCCTATG GCCACAGGGA GGCGTGGGGT GAAGGTTACC 
AAGCATAGCT CGGAAGAGGC TCGACCACAA TCTTGCCTGG TGGGCTCAGC CATTGGCAGA 
CCAGGTGGAG AAGGCAGCCC CAGCCCTAAG ACCCAGGAAA GCAGCCTCAA GCACCGGCTC 
TTCCGCAGCA TGTTCCTGTC CACTCCCGCC ACAGGCTCTG CAAGCAGCAG CAAGCCGGTC 
CCTCTGCCAC AGAACAAGCT CAATTCTGCT TTCCGACCAC CACAAAAAGA TTCCTCTTCA 
AACCTGGTAG CCAAGGCCCA GTCCTTGCCC TCAGATCAGC CCACGGGGAC CTTCAGTCCT 
CTGACCACCT CAGATACCAG CAGTCCCCAG AAGTCCCTCC GCACAGCCCC AGCCACTGGT 
CCACTTCCAG GCCGGTCTTC TCCAGCAGGC TCCCCCCGCA CCCGGCATGC CCAGATCAGC 
ACCAGCAATC TATACCTGCC CCAGGACCCC ACAGTGGCCA AGGGGGCCCT GGGTGGCGAA 
GACACAGGCA TCGTAACACA TGAGCAGTTC AAAGCTGCGC TCAGGATGGT GGTGGACCAG 
GGTGACCCTC GGCTGCTGCT GGACAGCTAT GTGAAGATTG GGGAGGGCTC CACGGGCATT 
GTGTGTCTGG CCCGGGAGAA GCATTCAGGT CGCCAGGTAG CAGTCAAGAT GATGGACCTC 
AGAAAGCAGC AACGCAGGGA ACTGCTCTTT AATGAGGTGG TGATCATGCG TGACTACCAG 
CACCTCAATG TGGTGGAGAT GTACAAGAGT TACCTGGTAG GAGAGGAGCT GTGGGTGCTG 
ATGGAGTTCC TGCAGGGCGG GGCCCTCACA GACATCATCT CCCAAGTCAG ACTCAATGAG 
GAACAGATTG CTACTGTGTG TGAAGCTGTG CTTCAGGCCT TGGCTTACCT GCACGCCCAG 
GGTGTCATCC ACCGAGACAT CAAGAGTGAT TCCATCCTGC TGACCCTTGA TGGCAGGGTG 
AAGCTCTCAG ACTTTGGGTT CTGTGCTCAG ATCAGCAAAG ATGTCCCCAA GAGAAAGTCT 
CTCGTAGGAA CTCCATACTG GATGGCTCCT GAGGTGATCT CCAGATCCCT GTACGCTACT 
GAGGTGGATA TCTGGTCTCT GGGCATCATG GTGATTGAGA TGGTGGATGG AGAACCCCCT 
TACTTCAGCG ACTCCCCAGT GCAAGCCATG AAGAGGCTCC GGGACAGCCC CCCACCCAAG 
CTAAAGAACT CTTACAAGGT CTCTCCAGTG CTGCGAGACT TCCTGGAACG AATGCTGGTA 
CGGGAACCCC AAGAGAGAGC CACAGCCCAG GAGCTCCTGG ATCACCCCTT TCTGCTGCAG 
ACGGGGCTGC CCGAGTGTCT GGTGCCTCTG ATACAGCTCT ACCGCAAGCA GACCTCCACC 
TGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Science signaling7(354)rs7(2014 Dec)
Guo Z,Neilson LJ,Zhong H,Murray PS,Zanivan S,Zaidel-Bar R

Prognostic significance of p21-activated kinase 6 expression in patients with clear cell renal cell carcinoma.
Annals of surgical oncology21 Suppl 4S575-83(2014 Dec)
Liu W,Liu H,Liu Y,Xu L,Zhang W,Zhu Y,Xu J,Gu J

Functional deficits in PAK5, PAK6 and PAK5/PAK6 knockout mice.
PloS one8(4)e61321(2013)
Furnari MA,Jobes ML,Nekrasova T,Minden A,Wagner GC

Upregulation of p21-activated Kinase 6 in rat brain cortex after traumatic brain injury.
Journal of molecular histology42(3)195-203(2011 Jun)
Zhao W,Yang J,Shi W,Wu X,Shao B,Wu Q,Chen J,Ni L

Targeted disruption of the Pak5 and Pak6 genes in mice leads to deficits in learning and locomotion.
Developmental biology322(1)95-108(2008 Oct)
Nekrasova T,Jobes ML,Ting JH,Wagner GC,Minden A

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Pak6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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