Slc39a13 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc39a13
Entrez Gene ID	295928
Full Name	solute carrier family 39 member 13
General protein information	Preferred Names solute carrier family 39 member 13 Names zinc transporter ZIP13 ZIP-13 solute carrier family 39 (metal ion transporter), member 13 solute carrier family 39 (zinc transporter), member 13 zrt- and Irt-like protein 13
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q24

mRNA and Protein(s)

mRNA	Protein	Name
XM_006234501.3	XP_006234563.1	zinc transporter ZIP13 isoform X1
XM_006234502.3	XP_006234564.1	zinc transporter ZIP13 isoform X2
NM_001039196.1	NP_001034285.1	zinc transporter ZIP13 precursor

Pathways from BioSystems

Homologies

	SLC39A13	XP_001107140.1
Danio rerio (zebrafish)	slc39a13	NP_001005306.3
Canis lupus familiaris (dog)	SLC39A13	XP_533188.1
Mus musculus (house mouse)	Slc39a13	NP_080997.1
Rattus norvegicus (Norway rat)	Slc39a13	NP_001034285.1
Gallus gallus (chicken)	SLC39A13	NP_001008471.1
Drosophila melanogaster (fruit fly)	CG7816	NP_733324.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003300	XP_319524.2
Homo sapiens (human)	SLC39A13	NP_001121697.1
Pan troglodytes (chimpanzee)	SLC39A13	XP_003313058.1
Xenopus tropicalis (tropical clawed frog)	slc39a13	XP_002942107.2
Bos taurus (cattle)	SLC39A13	NP_001091601.1
Caenorhabditis elegans (roundworm)	C14H10.1	NP_509719.2

Gene Ontology
Bibliography

Related articles in PubMed

Zinc deficiency mediates alcohol-induced apoptotic cell death in the liver of rats through activating ER and mitochondrial cell death pathways.
Sun Q, Zhong W, Zhang W, Li Q, Sun X, Tan X, Sun X, Dong D, Zhou Z
American journal of physiology. Gastrointestinal and liver physiology308(9)G757-66(2015 May)

Biochemical characterization of human ZIP13 protein: a homo-dimerized zinc transporter involved in the spondylocheiro dysplastic Ehlers-Danlos syndrome.
Bin BH, Fukada T, Hosaka T, Yamasaki S, Ohashi W, Hojyo S, Miyai T, Nishida K, Yokoyama S, Hirano T
The Journal of biological chemistry286(46)40255-65(2011 Nov)

Over-expression of Zip-13 mRNA in kidney and lung during dietary zinc deficiency in Wistar rats.
Guo L, Hu X, Xu T, Qi X, Wan Y, Liu X, Jiang Y, Zhang L
Molecular biology reports38(3)1869-74(2011 Mar)

Spondylocheiro dysplastic form of the Ehlers-Danlos syndrome--an autosomal-recessive entity caused by mutations in the zinc transporter gene SLC39A13.
Giunta C, El?ioglu NH, Albrecht B, Eich G, Chambaz C, Janecke AR, Yeowell H, Weis M, Eyre DR, Kraenzlin M, Steinmann B
American journal of human genetics82(6)1290-305(2008 Jun)

The zinc transporter SLC39A13/ZIP13 is required for connective tissue development; its involvement in BMP/TGF-beta signaling pathways.
Fukada T, Civic N, Furuichi T, Shimoda S, Mishima K, Higashiyama H, Idaira Y, Asada Y, Kitamura H, Yamasaki S, Hojyo S, Nakayama M, Ohara O, Koseki H, Dos Santos HG, Bonafe L, Ha-Vinh R, Zankl A, Unger S, Kraenzlin ME, Beckmann JS, Saito I, Rivolta C, Ikegawa S, Superti-Furga A, Hirano T
PloS one3(11)e3642(2008)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Zip-13 shows an up-regulation (P < 0.05) in zinc-deficiency group both in kidney and lung.
Title: Over-expression of Zip-13 mRNA in kidney and lung during dietary zinc deficiency in Wistar rats.

The following Slc39a13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc39a13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa42543	NM_001039196.1 Latest version!	Rattus norvegicus solute carrier family 39 member 13 (Slc39a13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa26074	XM_006234501.3 Latest version!	Rattus norvegicus solute carrier family 39 member 13 (Slc39a13), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa26075	XM_006234502.3 Latest version!	Rattus norvegicus solute carrier family 39 member 13 (Slc39a13), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc39a13 ( NM_001039196.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001034285.1 Rattus norvegicus solute carrier family 39 member 13 (Slc39a13), mRNA.

Price & Availability↑

CloneID	ORa42543
Clone ID Related Accession (Same CDS sequence)	NM_001039196.1
Accession Version	NM_001039196.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-15
Organism	Rattus norvegicus(Norway rat)
Product	zinc transporter ZIP13 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC112321.1. On Jan 29, 2006 this sequence version replaced XM_215779.3. ##Evidence-Data-START## Transcript exon combination :: BC112321.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCCTGGAT GTCCCTGCCC TGGCTGTGGT ATGGCAGGCC AGAGGCTCCT CTTCCTCACT 
GTCCTTGCCC TGGAGCTCCT GGAAAGGGCT GGAGGTTCCC AGCCAGCCCT CCGGAGCCTG 
GGGGCTGCAG CTGCCTGTCG CCTGGATAGT AAAGAAAGCG AGTCCTGGGG GGCTCTGCTG 
AGTGGGGAGC GACTGGACAC CTGGATCTGC TCCCTCTTGG GCTCTCTCAT GGTTGGGCTC 
AGTGGGGTTT TCCCCTTGCT GGTCATTCCC CTGGAGATGG GGACCATGTT ACAATCAGAA 
GCTGGAGCCT GGCGCCTGAA GCAGCTGCTC AGCTTTGCCT TAGGTGGACT CCTGGGCAAT 
GTGTTTCTGC ACTTGCTGCC AGAGGCGTGG GCCTACACCT GTAACATCAG CCCCGGTGTT 
GAAGGGCAGA GTCTGCAGCG ACAGCAACAA CTGGGGCTGT GGGTCATCGC TGGCTTCCTG 
ACCTTCCTGG CATTGGAGAA GATGTTCCTC AACTGCAAGG AGGAGGACCC TAGCCAGGCC 
CCCAGCAAAG ACCCCACTGC TGCCGCGCTC AATGGAGGCC ACTGTCTGGC CCAGCCGGCT 
GCAGAGCCCG GCCTGAGAGC CGTGGTCCGG AACCTCAAAG TCAGTGGCTA TCTCAACCTG 
CTGGCCAATA CCATTGACAA CTTCACCCAT GGGCTGGCTG TGGCTGCCAG CTTCCTTGTG 
AGCAAAAAGA TTGGGCTTCT AACCACCATG GCCATCCTCC TGCATGAGAT CCCCCATGAG 
GTGGGTGACT TTGCTATCCT GCTCCGGGCT GGCTTTGACC GATGGACCGC AGCCAAGCTA 
CAGTTTTCTA CAGCCCTGGG AGGCCTTCTG GGGGCCTGCT TTGCCATCTG TACGCAATCC 
CCCAAAGGAG TAGAGGAGAC GGTGGTCTGG ACCCTGCCCT TTACCTCAGG AGGCTTTCTC 
TATGTTGCCC TGGTGAATGT GCTACCTGAC CTCTTGGAGG AAGATGACCC ATGGCACCTA 
AATCCCCCTC TCCCAACAGG CACTCCCTGC AGCAGGTGCT GCTGCTCTGC TCCGGTATCG 
TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034285.1
CDS	169..1254
Translation	MPGCPCPGCGMAGQRLLFLTVLALELLERAGGSQPALRSLGAAAACRLDSKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLQSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCNISPGVEGQSLQRQQQLGLWVIAGFLTFLALEKMFLNCKEEDPSQAPSKDPTAAALNGGHCLAQPAAEPGLRAVVRNLKVSGYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWTAAKLQFSTALGGLLGACFAICTQSPKGVEETVVWTLPFTSGGFLYVALVNVLPDLLEEDDPWHLNPPLPTGTPCSRCCCSAPVSW

Target ORF information:

RefSeq Version	NM_001039196.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 39 member 13 (Slc39a13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039196.1

ORF Insert Sequence:

ATGCCTGGAT GTCCCTGCCC TGGCTGTGGT ATGGCAGGCC AGAGGCTCCT CTTCCTCACT 
GTCCTTGCCC TGGAGCTCCT GGAAAGGGCT GGAGGTTCCC AGCCAGCCCT CCGGAGCCTG 
GGGGCTGCAG CTGCCTGTCG CCTGGATAGT AAAGAAAGCG AGTCCTGGGG GGCTCTGCTG 
AGTGGGGAGC GACTGGACAC CTGGATCTGC TCCCTCTTGG GCTCTCTCAT GGTTGGGCTC 
AGTGGGGTTT TCCCCTTGCT GGTCATTCCC CTGGAGATGG GGACCATGTT ACAATCAGAA 
GCTGGAGCCT GGCGCCTGAA GCAGCTGCTC AGCTTTGCCT TAGGTGGACT CCTGGGCAAT 
GTGTTTCTGC ACTTGCTGCC AGAGGCGTGG GCCTACACCT GTAACATCAG CCCCGGTGTT 
GAAGGGCAGA GTCTGCAGCG ACAGCAACAA CTGGGGCTGT GGGTCATCGC TGGCTTCCTG 
ACCTTCCTGG CATTGGAGAA GATGTTCCTC AACTGCAAGG AGGAGGACCC TAGCCAGGCC 
CCCAGCAAAG ACCCCACTGC TGCCGCGCTC AATGGAGGCC ACTGTCTGGC CCAGCCGGCT 
GCAGAGCCCG GCCTGAGAGC CGTGGTCCGG AACCTCAAAG TCAGTGGCTA TCTCAACCTG 
CTGGCCAATA CCATTGACAA CTTCACCCAT GGGCTGGCTG TGGCTGCCAG CTTCCTTGTG 
AGCAAAAAGA TTGGGCTTCT AACCACCATG GCCATCCTCC TGCATGAGAT CCCCCATGAG 
GTGGGTGACT TTGCTATCCT GCTCCGGGCT GGCTTTGACC GATGGACCGC AGCCAAGCTA 
CAGTTTTCTA CAGCCCTGGG AGGCCTTCTG GGGGCCTGCT TTGCCATCTG TACGCAATCC 
CCCAAAGGAG TAGAGGAGAC GGTGGTCTGG ACCCTGCCCT TTACCTCAGG AGGCTTTCTC 
TATGTTGCCC TGGTGAATGT GCTACCTGAC CTCTTGGAGG AAGATGACCC ATGGCACCTA 
AATCCCCCTC TCCCAACAGG CACTCCCTGC AGCAGGTGCT GCTGCTCTGC TCCGGTATCG 
TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc39a13 ( XM_006234501.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006234563.1 Rattus norvegicus solute carrier family 39 member 13 (Slc39a13), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa26074
Clone ID Related Accession (Same CDS sequence)	XM_006234501.3
Accession Version	XM_006234501.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	zinc transporter ZIP13 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234501.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTGGAT GTCCCTGCCC TGGCTGTGGT ATGGCAGGCC AGAGGCTCCT CTTCCTCACT 
GTCCTTGCCC TGGAGCTCCT GGAAAGGGCT GGAGGTTCCC AGCCAGCCCT CCGGAGCCTG 
GGGGCTGCAG CTGCCTGTCG CCTGGATAGT AAAGAAAGCG AGTCCTGGGG GGCTCTGCTG 
AGTGGGGAGC GACTGGACAC CTGGATCTGC TCCCTCTTGG GCTCTCTCAT GGTTGGGCTC 
AGTGGGGTTT TCCCCTTGCT GGTCATTCCC CTGGAGATGG GGACCATGTT ACAATCAGAA 
GCTGGAGCCT GGCGCCTGAA GCAGCTGCTC AGCTTTGCCT TAGGTGGACT CCTGGGCAAT 
GTGTTTCTGC ACTTGCTGCC AGAGGCGTGG GCCTACACCT GTAACATCAG CCCCGGTGTT 
GAAGGGCAGA GTCTGCAGCG ACAGCAACAA CTGGGGCTGT GGGTCATCGC TGGCTTCCTG 
ACCTTCCTGG CATTGGAGAA GATGTTCCTC AACTGCAAGG AGGAGGACCC TAGCCAGGCC 
CCCAGCAAAG ACCCCACTGC TGCCGCGCTC AATGGAGGCC ACTGTCTGGC CCAGCCGGCT 
GCAGAGCCCG GCCTGAGAGC CGTGGTCCGG AACCTCAAAG TCAGTGGCTA TCTCAACCTG 
CTGGCCAATA CCATTGACAA CTTCACCCAT GGGCTGGCTG TGGCTGCCAG CTTCCTTGTG 
AGCAAAAAGA TTGGGCTTCT AACCACCATG GCCATCCTCC TGCATGAGAT CCCCCATGAG 
GTGGGTGACT TTGCTATCCT GCTCCGGGCT GGCTTTGACC GATGGACCGC AGCCAAGCTA 
CAGTTTTCTA CAGCCCTGGG AGGCCTTCTG GGGGCCTGCT TTGCCATCTG TACGCAATCC 
CCCAAAGGAG TAGAGGAGAC GGTGGTCTGG ACCCTGCCCT TTACCTCAGG AGGCTTTCTC 
TATGTTGCCC TGGTGAATGT GCTACCTGAC CTCTTGGAGG AAGATGACCC ATGGCACTCC 
CTGCAGCAGG TGCTGCTGCT CTGCTCCGGT ATCGTGGTGA TGGTGCTGCT CTCGTTGTTC 
GTTGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006234563.1
CDS	397..1485
Translation	MPGCPCPGCGMAGQRLLFLTVLALELLERAGGSQPALRSLGAAAACRLDSKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLQSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCNISPGVEGQSLQRQQQLGLWVIAGFLTFLALEKMFLNCKEEDPSQAPSKDPTAAALNGGHCLAQPAAEPGLRAVVRNLKVSGYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWTAAKLQFSTALGGLLGACFAICTQSPKGVEETVVWTLPFTSGGFLYVALVNVLPDLLEEDDPWHSLQQVLLLCSGIVVMVLLSLFVE

Target ORF information:

RefSeq Version	XM_006234501.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 39 member 13 (Slc39a13), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006234501.3

ORF Insert Sequence:

ATGCCTGGAT GTCCCTGCCC TGGCTGTGGT ATGGCAGGCC AGAGGCTCCT CTTCCTCACT 
GTCCTTGCCC TGGAGCTCCT GGAAAGGGCT GGAGGTTCCC AGCCAGCCCT CCGGAGCCTG 
GGGGCTGCAG CTGCCTGTCG CCTGGATAGT AAAGAAAGCG AGTCCTGGGG GGCTCTGCTG 
AGTGGGGAGC GACTGGACAC CTGGATCTGC TCCCTCTTGG GCTCTCTCAT GGTTGGGCTC 
AGTGGGGTTT TCCCCTTGCT GGTCATTCCC CTGGAGATGG GGACCATGTT ACAATCAGAA 
GCTGGAGCCT GGCGCCTGAA GCAGCTGCTC AGCTTTGCCT TAGGTGGACT CCTGGGCAAT 
GTGTTTCTGC ACTTGCTGCC AGAGGCGTGG GCCTACACCT GTAACATCAG CCCCGGTGTT 
GAAGGGCAGA GTCTGCAGCG ACAGCAACAA CTGGGGCTGT GGGTCATCGC TGGCTTCCTG 
ACCTTCCTGG CATTGGAGAA GATGTTCCTC AACTGCAAGG AGGAGGACCC TAGCCAGGCC 
CCCAGCAAAG ACCCCACTGC TGCCGCGCTC AATGGAGGCC ACTGTCTGGC CCAGCCGGCT 
GCAGAGCCCG GCCTGAGAGC CGTGGTCCGG AACCTCAAAG TCAGTGGCTA TCTCAACCTG 
CTGGCCAATA CCATTGACAA CTTCACCCAT GGGCTGGCTG TGGCTGCCAG CTTCCTTGTG 
AGCAAAAAGA TTGGGCTTCT AACCACCATG GCCATCCTCC TGCATGAGAT CCCCCATGAG 
GTGGGTGACT TTGCTATCCT GCTCCGGGCT GGCTTTGACC GATGGACCGC AGCCAAGCTA 
CAGTTTTCTA CAGCCCTGGG AGGCCTTCTG GGGGCCTGCT TTGCCATCTG TACGCAATCC 
CCCAAAGGAG TAGAGGAGAC GGTGGTCTGG ACCCTGCCCT TTACCTCAGG AGGCTTTCTC 
TATGTTGCCC TGGTGAATGT GCTACCTGAC CTCTTGGAGG AAGATGACCC ATGGCACTCC 
CTGCAGCAGG TGCTGCTGCT CTGCTCCGGT ATCGTGGTGA TGGTGCTGCT CTCGTTGTTC 
GTTGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc39a13 ( XM_006234502.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006234564.1 Rattus norvegicus solute carrier family 39 member 13 (Slc39a13), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa26075
Clone ID Related Accession (Same CDS sequence)	XM_006234502.3
Accession Version	XM_006234502.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	zinc transporter ZIP13 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234502.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTGGAT GTCCCTGCCC TGGCTGTGGT ATGGCAGGCC AGAGGCTCCT CTTCCTCACT 
GTCCTTGCCC TGGAGCTCCT GGAAAGGGCT GGAGGTTCCC AGCCAGCCCT CCGGAGCCTG 
GGGGCTGCAG CTGCCTGTCG CCTGGATAGT AAAGAAAGCG AGTCCTGGGG GGCTCTGCTG 
AGTGGGGAGC GACTGGACAC CTGGATCTGC TCCCTCTTGG GCTCTCTCAT GGTTGGGCTC 
AGTGGGGTTT TCCCCTTGCT GGTCATTCCC CTGGAGATGG GGACCATGTT ACAATCAGAA 
GCTGGAGCCT GGCGCCTGAA GCAGCTGCTC AGCTTTGCCT TAGGTGGACT CCTGGGCAAT 
GTGTTTCTGC ACTTGCTGCC AGAGGCGTGG GCCTACACCT GTAACATCAG CCCCGGTGTT 
GAAGGGCAGA GTCTGCAGCG ACAGCAACAA CTGGGGCTGT GGGTCATCGC TGGCTTCCTG 
ACCTTCCTGG CATTGGAGAA GATGTTCCTC AACTGCAAGG AGGAGGACCC TAGCCAGGTC 
AGTGGCTATC TCAACCTGCT GGCCAATACC ATTGACAACT TCACCCATGG GCTGGCTGTG 
GCTGCCAGCT TCCTTGTGAG CAAAAAGATT GGGCTTCTAA CCACCATGGC CATCCTCCTG 
CATGAGATCC CCCATGAGGT GGGTGACTTT GCTATCCTGC TCCGGGCTGG CTTTGACCGA 
TGGACCGCAG CCAAGCTACA GTTTTCTACA GCCCTGGGAG GCCTTCTGGG GGCCTGCTTT 
GCCATCTGTA CGCAATCCCC CAAAGGAGTA GAGGAGACGG TGGTCTGGAC CCTGCCCTTT 
ACCTCAGGAG GCTTTCTCTA TGTTGCCCTG GTGAATGTGC TACCTGACCT CTTGGAGGAA 
GATGACCCAT GGCACTCCCT GCAGCAGGTG CTGCTGCTCT GCTCCGGTAT CGTGGTGATG 
GTGCTGCTCT CGTTGTTCGT TGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006234564.1
CDS	404..1390
Translation	MPGCPCPGCGMAGQRLLFLTVLALELLERAGGSQPALRSLGAAAACRLDSKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLQSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCNISPGVEGQSLQRQQQLGLWVIAGFLTFLALEKMFLNCKEEDPSQVSGYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWTAAKLQFSTALGGLLGACFAICTQSPKGVEETVVWTLPFTSGGFLYVALVNVLPDLLEEDDPWHSLQQVLLLCSGIVVMVLLSLFVE

Target ORF information:

RefSeq Version	XM_006234502.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 39 member 13 (Slc39a13), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006234502.3

ORF Insert Sequence:

ATGCCTGGAT GTCCCTGCCC TGGCTGTGGT ATGGCAGGCC AGAGGCTCCT CTTCCTCACT 
GTCCTTGCCC TGGAGCTCCT GGAAAGGGCT GGAGGTTCCC AGCCAGCCCT CCGGAGCCTG 
GGGGCTGCAG CTGCCTGTCG CCTGGATAGT AAAGAAAGCG AGTCCTGGGG GGCTCTGCTG 
AGTGGGGAGC GACTGGACAC CTGGATCTGC TCCCTCTTGG GCTCTCTCAT GGTTGGGCTC 
AGTGGGGTTT TCCCCTTGCT GGTCATTCCC CTGGAGATGG GGACCATGTT ACAATCAGAA 
GCTGGAGCCT GGCGCCTGAA GCAGCTGCTC AGCTTTGCCT TAGGTGGACT CCTGGGCAAT 
GTGTTTCTGC ACTTGCTGCC AGAGGCGTGG GCCTACACCT GTAACATCAG CCCCGGTGTT 
GAAGGGCAGA GTCTGCAGCG ACAGCAACAA CTGGGGCTGT GGGTCATCGC TGGCTTCCTG 
ACCTTCCTGG CATTGGAGAA GATGTTCCTC AACTGCAAGG AGGAGGACCC TAGCCAGGTC 
AGTGGCTATC TCAACCTGCT GGCCAATACC ATTGACAACT TCACCCATGG GCTGGCTGTG 
GCTGCCAGCT TCCTTGTGAG CAAAAAGATT GGGCTTCTAA CCACCATGGC CATCCTCCTG 
CATGAGATCC CCCATGAGGT GGGTGACTTT GCTATCCTGC TCCGGGCTGG CTTTGACCGA 
TGGACCGCAG CCAAGCTACA GTTTTCTACA GCCCTGGGAG GCCTTCTGGG GGCCTGCTTT 
GCCATCTGTA CGCAATCCCC CAAAGGAGTA GAGGAGACGG TGGTCTGGAC CCTGCCCTTT 
ACCTCAGGAG GCTTTCTCTA TGTTGCCCTG GTGAATGTGC TACCTGACCT CTTGGAGGAA 
GATGACCCAT GGCACTCCCT GCAGCAGGTG CTGCTGCTCT GCTCCGGTAT CGTGGTGATG 
GTGCTGCTCT CGTTGTTCGT TGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Zinc deficiency mediates alcohol-induced apoptotic cell death in the liver of rats through activating ER and mitochondrial cell death pathways.
American journal of physiology. Gastrointestinal and liver physiology308(9)G757-66(2015 May)
Sun Q,Zhong W,Zhang W,Li Q,Sun X,Tan X,Sun X,Dong D,Zhou Z

Biochemical characterization of human ZIP13 protein: a homo-dimerized zinc transporter involved in the spondylocheiro dysplastic Ehlers-Danlos syndrome.
The Journal of biological chemistry286(46)40255-65(2011 Nov)
Bin BH,Fukada T,Hosaka T,Yamasaki S,Ohashi W,Hojyo S,Miyai T,Nishida K,Yokoyama S,Hirano T

Over-expression of Zip-13 mRNA in kidney and lung during dietary zinc deficiency in Wistar rats.
Molecular biology reports38(3)1869-74(2011 Mar)
Guo L,Hu X,Xu T,Qi X,Wan Y,Liu X,Jiang Y,Zhang L

Spondylocheiro dysplastic form of the Ehlers-Danlos syndrome--an autosomal-recessive entity caused by mutations in the zinc transporter gene SLC39A13.
American journal of human genetics82(6)1290-305(2008 Jun)
Giunta C,El?ioglu NH,Albrecht B,Eich G,Chambaz C,Janecke AR,Yeowell H,Weis M,Eyre DR,Kraenzlin M,Steinmann B

The zinc transporter SLC39A13/ZIP13 is required for connective tissue development; its involvement in BMP/TGF-beta signaling pathways.
PloS one3(11)e3642(2008)
Fukada T,Civic N,Furuichi T,Shimoda S,Mishima K,Higashiyama H,Idaira Y,Asada Y,Kitamura H,Yamasaki S,Hojyo S,Nakayama M,Ohara O,Koseki H,Dos Santos HG,Bonafe L,Ha-Vinh R,Zankl A,Unger S,Kraenzlin ME,Beckmann JS,Saito I,Rivolta C,Ikegawa S,Superti-Furga A,Hirano T

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Slc39a13 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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