Nus1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nus1
Entrez Gene ID	294400
Full Name	NUS1 dehydrodolichyl diphosphate synthase subunit
Synonyms	RGD1307879
General protein information	Preferred Names NUS1 dehydrodolichyl diphosphate synthase subunit Names dehydrodolichyl diphosphate synthase complex subunit NUS1 nogo-B receptor nuclear undecaprenyl pyrophosphate synthase 1 homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20q11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001164157.1	NP_001157629.1	dehydrodolichyl diphosphate synthase complex subunit NUS1

Pathways from BioSystems

Homologies

	NUS1	XP_001110733.1
Bos taurus (cattle)	NUS1	NP_001242897.1
Homo sapiens (human)	NUS1	NP_612468.1
Mus musculus (house mouse)	Nus1	NP_084526.1
Canis lupus familiaris (dog)	NUS1	XP_541219.2
Rattus norvegicus (Norway rat)	Nus1	NP_001157629.1
Gallus gallus (chicken)	NUS1	XP_419766.3
Danio rerio (zebrafish)	nus1	NP_001002356.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000402	XP_565967.3
Pan troglodytes (chimpanzee)	NUS1	XP_518713.1

Gene Ontology
Bibliography

Related articles in PubMed

A conserved C-terminal R
Grabi?ska KA, Edani BH, Park EJ, Kraehling JR, Sessa WC
The Journal of biological chemistry292(42)17351-17361(2017 10)

Endothelial miR-26a regulates VEGF-Nogo-B receptor-mediated angiogenesis.
Jo HN, Kang H, Lee A, Choi J, Chang W, Lee MS, Kim J
BMB reports50(7)384-389(2017 Jul)

Mutation of Nogo-B receptor, a subunit of cis-prenyltransferase, causes a congenital disorder of glycosylation.
Park EJ, Grabi?ska KA, Guan Z, Str?neck? V, Hartmannov? H, Hoda?ov? K, Bare?ov? V, Sovov? J, Jozsef L, Ondru?kov? N, Hans?kov? H, Honz?k T, Zeman J, H?lkov? H, Wen R, Kmoch S, Sessa WC
Cell metabolism20(3)448-57(2014 Sep)

Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking.
Harrison KD, Miao RQ, Fernandez-Hern?ndo C, Su?rez Y, D?valos A, Sessa WC
Cell metabolism10(3)208-18(2009 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Nus1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nus1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04805	NM_001164157.1 Latest version!	Rattus norvegicus NUS1 dehydrodolichyl diphosphate synthase subunit (Nus1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nus1 ( NM_001164157.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001157629.1 Rattus norvegicus NUS1 dehydrodolichyl diphosphate synthase subunit (Nus1), mRNA.

Price & Availability↑

CloneID	ORa04805
Clone ID Related Accession (Same CDS sequence)	NM_001164157.1
Accession Version	NM_001164157.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Rattus norvegicus(Norway rat)
Product	dehydrodolichyl diphosphate synthase complex subunit NUS1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB720603.1, BQ782237.1, CK363676.1, CO405351.1, DY312007.1, FM091992.1, CF107108.1 and CB718508.1. On or before Aug 14, 2009 this sequence version replaced XM_001058252.1, XM_215387.4. ##Evidence-Data-START## Transcript exon combination :: CK363676.1, DV214413.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGACGGGGC TGTACGAGCT GGTGTGGCGG GTGCTGCACT TGCTGTTCTG CCTGTACCGC 
ACGCTCACCT CCTGGCTCCG CGTTCGCTTC GGCACATGGA ACTGGATCTG GCGGCGCTGC 
TGTCGCGCCG CCTCCGCCGC GGTCCTAGCG CCGCTCGGCT TCACGCTCCG CAAGCTCCCG 
GCCGTCGGCA GGAACCGGCG TCATCACCGG CACCCGCACC GGGGACCGGG ACCGGCCGCC 
ACCCACCCCC GGCTGCGCTG GCGCGCGGAC GGCCGGTCCC TGCAGAAGCT GCCGGTGCAC 
ATGGGCCTGG TGATCACCGA GGAAGTGCAA GAGCCCAGCT TCTCAGACAT CGCCAGCCTC 
GTGGTGTGGT GTATGGCCGT GGGGATCTCC TACATTAGCG TCTACGACCA CCAAGGTATT 
TTCAAGAGAA ATAATTCCAG ATTGATGGAT GAAATTTTAA AACAACAGCA GGAACTTTTG 
GGCCAAGATT GTTCCAAATA CTCAGCAGAG TTTGCAAATA GTAACGACAA AGACGATCAA 
GTTTTAAATT GCCCATCGGC GGTGAAGGTG CTGTCCCCAG AAGACGGAAA AGCCGACATT 
GTGCGAGCCG CCCAGGACTT TTGCCAGTCA GTAGCCCAGC AGCAGAGGAG GCCGACGGAG 
CTGGGTGTAG AGCTGCTCGA CAGCTTACTG AGTTCACATG GCTTCCCTGA TCCTGACTTA 
GTGTTGAAGT TTGGTCCTGT GGACAGCACG TTAGGCTTTC TTCCCTGGCA AATCAGATTG 
ACTGAGATCA TCTCTTTGCC TTCTCACTCA AACATCAGCT ATGAGGACCT TTTCTCCGCC 
CTCCGGCAGT ATGCAGCTTG TGAACAGCGT CTGGGGAAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001157629.1
CDS	92..973
Translation	MTGLYELVWRVLHLLFCLYRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKLPAVGRNRRHHRHPHRGPGPAATHPRLRWRADGRSLQKLPVHMGLVITEEVQEPSFSDIASLVVWCMAVGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGQDCSKYSAEFANSNDKDDQVLNCPSAVKVLSPEDGKADIVRAAQDFCQSVAQQQRRPTELGVELLDSLLSSHGFPDPDLVLKFGPVDSTLGFLPWQIRLTEIISLPSHSNISYEDLFSALRQYAACEQRLGK

Target ORF information:

RefSeq Version	NM_001164157.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus NUS1 dehydrodolichyl diphosphate synthase subunit (Nus1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001164157.1

ORF Insert Sequence:

ATGACGGGGC TGTACGAGCT GGTGTGGCGG GTGCTGCACT TGCTGTTCTG CCTGTACCGC 
ACGCTCACCT CCTGGCTCCG CGTTCGCTTC GGCACATGGA ACTGGATCTG GCGGCGCTGC 
TGTCGCGCCG CCTCCGCCGC GGTCCTAGCG CCGCTCGGCT TCACGCTCCG CAAGCTCCCG 
GCCGTCGGCA GGAACCGGCG TCATCACCGG CACCCGCACC GGGGACCGGG ACCGGCCGCC 
ACCCACCCCC GGCTGCGCTG GCGCGCGGAC GGCCGGTCCC TGCAGAAGCT GCCGGTGCAC 
ATGGGCCTGG TGATCACCGA GGAAGTGCAA GAGCCCAGCT TCTCAGACAT CGCCAGCCTC 
GTGGTGTGGT GTATGGCCGT GGGGATCTCC TACATTAGCG TCTACGACCA CCAAGGTATT 
TTCAAGAGAA ATAATTCCAG ATTGATGGAT GAAATTTTAA AACAACAGCA GGAACTTTTG 
GGCCAAGATT GTTCCAAATA CTCAGCAGAG TTTGCAAATA GTAACGACAA AGACGATCAA 
GTTTTAAATT GCCCATCGGC GGTGAAGGTG CTGTCCCCAG AAGACGGAAA AGCCGACATT 
GTGCGAGCCG CCCAGGACTT TTGCCAGTCA GTAGCCCAGC AGCAGAGGAG GCCGACGGAG 
CTGGGTGTAG AGCTGCTCGA CAGCTTACTG AGTTCACATG GCTTCCCTGA TCCTGACTTA 
GTGTTGAAGT TTGGTCCTGT GGACAGCACG TTAGGCTTTC TTCCCTGGCA AATCAGATTG 
ACTGAGATCA TCTCTTTGCC TTCTCACTCA AACATCAGCT ATGAGGACCT TTTCTCCGCC 
CTCCGGCAGT ATGCAGCTTG TGAACAGCGT CTGGGGAAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A conserved C-terminal R
The Journal of biological chemistry292(42)17351-17361(2017 10)
Grabi?ska KA,Edani BH,Park EJ,Kraehling JR,Sessa WC

Endothelial miR-26a regulates VEGF-Nogo-B receptor-mediated angiogenesis.
BMB reports50(7)384-389(2017 Jul)
Jo HN,Kang H,Lee A,Choi J,Chang W,Lee MS,Kim J

Mutation of Nogo-B receptor, a subunit of cis-prenyltransferase, causes a congenital disorder of glycosylation.
Cell metabolism20(3)448-57(2014 Sep)
Park EJ,Grabi?ska KA,Guan Z,Str?neck? V,Hartmannov? H,Hoda?ov? K,Bare?ov? V,Sovov? J,Jozsef L,Ondru?kov? N,Hans?kov? H,Honz?k T,Zeman J,H?lkov? H,Wen R,Kmoch S,Sessa WC

Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking.
Cell metabolism10(3)208-18(2009 Sep)
Harrison KD,Miao RQ,Fernandez-Hern?ndo C,Su?rez Y,D?valos A,Sessa WC