Ube2g2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ube2g2
Entrez Gene ID	294331
Full Name	ubiquitin-conjugating enzyme E2G 2
General protein information	Preferred Names ubiquitin-conjugating enzyme E2G 2 Names ubiquitin-conjugating enzyme E2 G2 ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20p12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001106380.1	NP_001099850.1	ubiquitin-conjugating enzyme E2 G2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	UBE2G2	XP_535603.4
Danio rerio (zebrafish)	ube2g2	NP_001017767.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002169	XP_308019.4
Eremothecium gossypii	AGOS_ABR059W	NP_983005.1
	UBE2G2	XP_001101137.1
Bos taurus (cattle)	UBE2G2	NP_001069796.1
Gallus gallus (chicken)	UBE2G2	NP_001264348.1
Homo sapiens (human)	UBE2G2	NP_003334.2
Rattus norvegicus (Norway rat)	Ube2g2	NP_001099850.1
Kluyveromyces lactis	KLLA0E07745g	XP_454298.1
Schizosaccharomyces pombe (fission yeast)	ubc7	NP_595778.1
Neurospora crassa	NCU03623	XP_961350.1
Xenopus tropicalis (tropical clawed frog)	ube2g2	NP_001017198.1
Mus musculus (house mouse)	Ube2g2	NP_062777.2
Drosophila melanogaster (fruit fly)	crl	NP_524684.2
Magnaporthe oryzae (rice blast fungus)	MGG_04081	XP_003719757.1
Pan troglodytes (chimpanzee)	UBE2G2	XP_003949245.1
Caenorhabditis elegans (roundworm)	ubc-14	NP_493381.1
Saccharomyces cerevisiae (baker's yeast)	UBC7	NP_013735.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of ERAD components essential for dislocation of the null Hong Kong variant of ?-1-antitrypsin (NHK).
Zhong Y, Shen H, Wang Y, Yang Y, Yang P, Fang S
Biochemical and biophysical research communications458(2)424-8(2015 Mar)

Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKK? kinase-mediated antiviral response.
Rajsbaum R, Versteeg GA, Schmid S, Maestre AM, Belicha-Villanueva A, Mart?nez-Romero C, Patel JR, Morrison J, Pisanelli G, Miorin L, Laurent-Rolle M, Moulton HM, Stein DA, Fernandez-Sesma A, tenOever BR, Garc?a-Sastre A
Immunity40(6)880-95(2014 Jun)

Dimeric Ube2g2 simultaneously engages donor and acceptor ubiquitins to form Lys48-linked ubiquitin chains.
Liu W, Shang Y, Zeng Y, Liu C, Li Y, Zhai L, Wang P, Lou J, Xu P, Ye Y, Li W
The EMBO journal33(1)46-61(2014 Jan)

STT3B-dependent posttranslational N-glycosylation as a surveillance system for secretory protein.
Sato T, Sako Y, Sho M, Momohara M, Suico MA, Shuto T, Nishitoh H, Okiyoneda T, Kokame K, Kaneko M, Taura M, Miyata M, Chosa K, Koga T, Morino-Koga S, Wada I, Kai H
Molecular cell47(1)99-110(2012 Jul)

Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.
Shibata E, Abbas T, Huang X, Wohlschlegel JA, Dutta A
Molecular and cellular biology31(15)3136-45(2011 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ube2g2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ube2g2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01108	NM_001106380.1 Latest version!	Rattus norvegicus ubiquitin-conjugating enzyme E2G 2 (Ube2g2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ube2g2 ( NM_001106380.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099850.1 Rattus norvegicus ubiquitin-conjugating enzyme E2G 2 (Ube2g2), mRNA.

Price & Availability↑

CloneID	ORa01108
Clone ID Related Accession (Same CDS sequence)	NM_001106380.1
Accession Version	NM_001106380.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 498bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	ubiquitin-conjugating enzyme E2 G2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473988.1. On or before Oct 4, 2007 this sequence version replaced XM_215371.4, XM_001079504.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC166733.1, EV778578.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906348, SAMN01906357 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGGGA CGGCGTTGAA GAGGCTGATG GCCGAATATA AGCAATTAAC CCTGAATCCT 
CCAGAAGGAA TTGTGGCAGG CCCCATGAAT GAAGAGAATT TTTTTGAATG GGAGGCATTG 
ATCATGGGCC CTGAAGACAC TTGCTTTGAG TTTGGTGTTT TCCCCGCCAT CCTGAGTTTC 
CCACTTGACT ACCCTTTGAG CCCTCCGAAA ATGAGATTCA CCTGTGAGAT GTTCCATCCC 
AACATCTACC CTGACGGAAG AGTGTGCATC TCCATCCTGC ATGCCCCAGG GGACGACCCC 
ATGGGCTATG AGAGCAGTGC CGAGCGGTGG AGCCCAGTGC AGAGTGTGGA GAAGATCCTG 
CTTTCGGTGG TGAGCATGCT GGCAGAGCCC AATGATGAGA GTGGAGCAAA CGTAGACGCT 
TCCAAGATGT GGCGGGACGA CCGTGAGCAG TTCTACAAGA TTGCCAAGCA GATCGTACAG 
AAGTCTCTGG GGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099850.1
CDS	73..570
Translation	MAGTALKRLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLSVVSMLAEPNDESGANVDASKMWRDDREQFYKIAKQIVQKSLGL

Target ORF information:

RefSeq Version	NM_001106380.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ubiquitin-conjugating enzyme E2G 2 (Ube2g2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106380.1

ORF Insert Sequence:

ATGGCGGGGA CGGCGTTGAA GAGGCTGATG GCCGAATATA AGCAATTAAC CCTGAATCCT 
CCAGAAGGAA TTGTGGCAGG CCCCATGAAT GAAGAGAATT TTTTTGAATG GGAGGCATTG 
ATCATGGGCC CTGAAGACAC TTGCTTTGAG TTTGGTGTTT TCCCCGCCAT CCTGAGTTTC 
CCACTTGACT ACCCTTTGAG CCCTCCGAAA ATGAGATTCA CCTGTGAGAT GTTCCATCCC 
AACATCTACC CTGACGGAAG AGTGTGCATC TCCATCCTGC ATGCCCCAGG GGACGACCCC 
ATGGGCTATG AGAGCAGTGC CGAGCGGTGG AGCCCAGTGC AGAGTGTGGA GAAGATCCTG 
CTTTCGGTGG TGAGCATGCT GGCAGAGCCC AATGATGAGA GTGGAGCAAA CGTAGACGCT 
TCCAAGATGT GGCGGGACGA CCGTGAGCAG TTCTACAAGA TTGCCAAGCA GATCGTACAG 
AAGTCTCTGG GGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of ERAD components essential for dislocation of the null Hong Kong variant of ?-1-antitrypsin (NHK).
Biochemical and biophysical research communications458(2)424-8(2015 Mar)
Zhong Y,Shen H,Wang Y,Yang Y,Yang P,Fang S

Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKK? kinase-mediated antiviral response.
Immunity40(6)880-95(2014 Jun)
Rajsbaum R,Versteeg GA,Schmid S,Maestre AM,Belicha-Villanueva A,Mart?nez-Romero C,Patel JR,Morrison J,Pisanelli G,Miorin L,Laurent-Rolle M,Moulton HM,Stein DA,Fernandez-Sesma A,tenOever BR,Garc?a-Sastre A

Dimeric Ube2g2 simultaneously engages donor and acceptor ubiquitins to form Lys48-linked ubiquitin chains.
The EMBO journal33(1)46-61(2014 Jan)
Liu W,Shang Y,Zeng Y,Liu C,Li Y,Zhai L,Wang P,Lou J,Xu P,Ye Y,Li W

STT3B-dependent posttranslational N-glycosylation as a surveillance system for secretory protein.
Molecular cell47(1)99-110(2012 Jul)
Sato T,Sako Y,Sho M,Momohara M,Suico MA,Shuto T,Nishitoh H,Okiyoneda T,Kokame K,Kaneko M,Taura M,Miyata M,Chosa K,Koga T,Morino-Koga S,Wada I,Kai H

Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.
Molecular and cellular biology31(15)3136-45(2011 Aug)
Shibata E,Abbas T,Huang X,Wohlschlegel JA,Dutta A