Adra1a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adra1a
Entrez Gene ID	29412
Full Name	adrenoceptor alpha 1A
Synonyms	Adra1c
General protein information	Preferred Names adrenoceptor alpha 1A Names alpha-1A adrenergic receptor adrenergic alpha 1c receptor adrenergic receptor alpha 1c subtype adrenergic receptor, alpha 1a adrenergic receptor, alpha 1c adrenergic, alpha-1A-, receptor alpha-1A adrenoceptor alpha-1A adrenoreceptor alpha-1C adrenergic receptor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p12
Summary	binds adrenergic compounds and analogs; activates phospholipase C mediated signal transduction [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006252107.3	XP_006252169.1	alpha-1A adrenergic receptor isoform X1
XM_006252109.3	XP_006252171.1	alpha-1A adrenergic receptor isoform X3
XM_008770744.2	XP_008768966.1	alpha-1A adrenergic receptor isoform X1
XM_006252108.3	XP_006252170.1	alpha-1A adrenergic receptor isoform X2
XM_006252110.3	XP_006252172.1	alpha-1A adrenergic receptor isoform X4
NM_017191.2	NP_058887.2	alpha-1A adrenergic receptor

Pathways from BioSystems

Homologies

	ADRA1A	NP_001108205.1
Canis lupus familiaris (dog)	ADRA1A	NP_001182772.1
Mus musculus (house mouse)	Adra1a	NP_038489.2
Caenorhabditis elegans (roundworm)	dop-4	NP_508238.2
Rattus norvegicus (Norway rat)	Adra1a	NP_058887.2
Anopheles gambiae (African malaria mosquito)	GPROAR1	XP_311113.4
Xenopus tropicalis (tropical clawed frog)	LOC100492776	XP_002933012.2
Bos taurus (cattle)	ADRA1A	NP_776923.1
Gallus gallus (chicken)	ADRA1A	XP_425762.2
Homo sapiens (human)	ADRA1A	NP_000671.2
Pan troglodytes (chimpanzee)	ADRA1A	XP_003311731.1
Danio rerio (zebrafish)	LOC798498	XP_001338938.2
Drosophila melanogaster (fruit fly)	Oamb	NP_732542.1

Gene Ontology
Bibliography

Related articles in PubMed

Receptor- and cellular compartment-specific activation of the cAMP/PKA pathway by ?
Martin RD, Sun Y, Bourque K, Audet N, Inoue A, Tanny JC, H?bert TE
Cellular signalling4443-50(2018 Jan)

The water avoidance stress induces bladder pain due to a prolonged alpha1A adrenoceptor stimulation.
Matos R, Serr?o P, Rodriguez L, Birder LA, Cruz F, Charrua A
Naunyn-Schmiedeberg's archives of pharmacology390(8)839-844(2017 Aug)

MRI Assessment of Cardiomyopathy Induced by ?1-Adrenoreceptor Autoantibodies and Protection Through ?3-Adrenoreceptor Overexpression.
Vanhoutte L, Guilbaud C, Martherus R, Bouzin C, Gallez B, Dessy C, Balligand JL, Moniotte S, Feron O
Scientific reports743951(2017 Mar)

Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth.
Cheng Z, Zhu Q, Dee R, Opheim Z, Mack CP, Cyr DM, Taylor JM
The Journal of biological chemistry292(6)2065-2079(2017 02)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the excitatory input and post-synaptic dynamics of pontine reticular nucleus reticulospinal neurons are indeed intricately modulated by the activation of alpha1- and alpha2-adrenoceptors.
Title: Adrenoceptor-Mediated Post- and Pre-Synaptic Regulations of the Reticulospinal Neurons in Rat Caudal Pontine Reticular Nucleus.

effects of female sexual hormones on the expression and function of alpha1A- and alpha1D-adrenoceptor subtypes in the late-pregnant rat myometrium
Title: The effects of female sexual hormones on the expression and function of ?1A- and ?1D-adrenoceptor subtypes in the late-pregnant rat myometrium.

Silodosin, a selective alpha(1A)-adrenoceptor antagonist, improves voiding behavior in rat models with BOO by inducing recovery of bladder blood flow.
Title: Effect of silodosin, a selective ?(1A)-adrenoceptor antagonist, on voiding behavior and bladder blood flow in a rat model of bladder outlet obstruction.

Our data suggest that PKCalpha, beta and epsilon activation may underlie physiological and pathophysiological responses of alpha1-AR signaling for the phosphorylation of membrane-associated substrates including ion-channel and transporter proteins.
Title: Isoform-specific dynamic translocation of PKC by ?1-adrenoceptor stimulation in live cells.

These findings indicated that noradrenaline activates alpha1-adrenoceptors, which were found to be the main receptors in Ca(2+)-related cell homeostasis and protein (including mucin) secretion in rats lacrimal glands.
Title: ?1-Adrenoceptors relate Ca(2+) modulation and protein secretions in rat lacrimal gland.

The following Adra1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adra1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa12739	NM_017191.2 Latest version!	Rattus norvegicus adrenoceptor alpha 1A (Adra1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa12739	XM_008770744.2 Latest version!	Rattus norvegicus adrenoceptor alpha 1A (Adra1a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa12739	XM_006252107.3 Latest version!	Rattus norvegicus adrenoceptor alpha 1A (Adra1a), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa36755	XM_006252108.3 Latest version!	Rattus norvegicus adrenoceptor alpha 1A (Adra1a), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa36756	XM_006252109.3 Latest version!	Rattus norvegicus adrenoceptor alpha 1A (Adra1a), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa36757	XM_006252110.3 Latest version!	Rattus norvegicus adrenoceptor alpha 1A (Adra1a), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adra1a ( NM_017191.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_058887.2 Rattus norvegicus adrenoceptor alpha 1A (Adra1a), mRNA.

Price & Availability↑

CloneID	ORa12739
Clone ID Related Accession (Same CDS sequence)	XM_006252107.3 , XM_008770744.2 , NM_017191.2
Accession Version	NM_017191.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1401bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	alpha-1A adrenergic receptor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U07126.1. On Jun 10, 2007 this sequence version replaced NM_017191.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U07126.1, U13368.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGTGCTTC TCTCTGAAAA TGCTTCGGAA GGCTCCAACT GCACCCACCC ACCAGCTCCG 
GTGAACATTT CTAAGGCCAT TCTGCTTGGG GTGATCTTGG GGGGCCTCAT CATTTTCGGA 
GTCCTGGGGA ACATTTTAGT GATCCTCTCA GTGGCCTGTC ATCGGCATCT GCACTCCGTG 
ACTCACTACT ACATTGTCAA CCTGGCTGTG GCAGACCTCC TCCTCACCTC CACTGTGCTG 
CCCTTCTCTG CCATCTTTGA GATCCTGGGC TACTGGGCCT TTGGCAGGGT GTTCTGCAAT 
ATCTGGGCGG CCGTGGACGT CTTATGCTGC ACAGCGTCCA TCATGGGCCT CTGCATCATC 
TCCATCGACC GATACATTGG TGTGAGCTAC CCGCTGCGCT ATCCCACCAT TGTCACCCAG 
AGGAGGGGCG TCAGGGCTCT GCTCTGCGTC TGGGTGCTTT CTTTGGTCAT CTCCATCGGA 
CCCCTGTTCG GCTGGAGGCA GCCGGCTCCA GAGGATGAGA CCATCTGCCA GATCAATGAG 
GAGCCGGGCT ACGTGCTGTT CTCAGCGCTG GGCTCTTTCT ACGTGCCACT GGCCATCATT 
CTGGTTATGT ACTGTCGAGT CTACGTAGTA GCCAAGAGAG AAAGCCGGGG CCTCAAGTCC 
GGCCTCAAGA CGGACAAGTC AGACTCAGAG CAAGTGACGC TCCGCATCCA CCGTAAAAAT 
GTCCCTGCAG AAGGCGGCGG AGTCAGCAGT GCCAAGAATA AGACTCACTT CTCAGTGAGG 
CTGCTCAAGT TTTCTCGAGA GAAGAAAGCT GCCAAGACGC TGGGCATCGT GGTGGGTTGC 
TTCGTCCTCT GCTGGCTGCC GTTCTTCCTA GTGATGCCCA TTGGGTCTTT CTTCCCGGAT 
TTCAAGCCTT CGGAAACCGT TTTTAAAATA GTATTTTGGC TCGGGTATCT AAATAGTTGC 
ATCAACCCTA TCATATACCC ATGCTCCAGC CAGGAGTTCA AGAAAGCCTT TCAGAATGTC 
CTGCGAATCC AGTGTCTTCG CAGAAGGCAG TCTTCCAAGC ATGCCCTGGG CTATACCCTG 
CACCCGCCCA GCCAGGCTCT AGAGGGACAG CACAGAGACA TGGTGCGTAT CCCGGTGGGC 
TCGGGAGAGA CTTTCTATAA GATCTCCAAG ACAGATGGAG TCTGTGAATG GAAGTTTTTC 
TCTTCCATGC CCCAGGGATC GGCCAGGATT ACAGTGCCAA AGGACCAATC TGCCTGTACC 
ACAGCCCGGG TGAGAAGTAA AAGCTTTTTG CAGGTCTGCT GCTGTGTGGG GTCCTCGGCC 
CCGCGCCCTG AAGAAAATCA CCAAGTTCCA ACCATTAAGA TCCACACCAT CTCCCTCGGT 
GAAAACGGGG AGGAAGTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058887.2
CDS	16..1416
Translation	MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNVPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTLHPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACTTARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV

Target ORF information:

RefSeq Version	NM_017191.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adrenoceptor alpha 1A (Adra1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017191.2

ORF Insert Sequence:

ATGGTGCTTC TCTCTGAAAA TGCTTCGGAA GGCTCCAACT GCACCCACCC ACCAGCTCCG 
GTGAACATTT CTAAGGCCAT TCTGCTTGGG GTGATCTTGG GGGGCCTCAT CATTTTCGGA 
GTCCTGGGGA ACATTTTAGT GATCCTCTCA GTGGCCTGTC ATCGGCATCT GCACTCCGTG 
ACTCACTACT ACATTGTCAA CCTGGCTGTG GCAGACCTCC TCCTCACCTC CACTGTGCTG 
CCCTTCTCTG CCATCTTTGA GATCCTGGGC TACTGGGCCT TTGGCAGGGT GTTCTGCAAT 
ATCTGGGCGG CCGTGGACGT CTTATGCTGC ACAGCGTCCA TCATGGGCCT CTGCATCATC 
TCCATCGACC GATACATTGG TGTGAGCTAC CCGCTGCGCT ATCCCACCAT TGTCACCCAG 
AGGAGGGGCG TCAGGGCTCT GCTCTGCGTC TGGGTGCTTT CTTTGGTCAT CTCCATCGGA 
CCCCTGTTCG GCTGGAGGCA GCCGGCTCCA GAGGATGAGA CCATCTGCCA GATCAATGAG 
GAGCCGGGCT ACGTGCTGTT CTCAGCGCTG GGCTCTTTCT ACGTGCCACT GGCCATCATT 
CTGGTTATGT ACTGTCGAGT CTACGTAGTA GCCAAGAGAG AAAGCCGGGG CCTCAAGTCC 
GGCCTCAAGA CGGACAAGTC AGACTCAGAG CAAGTGACGC TCCGCATCCA CCGTAAAAAT 
GTCCCTGCAG AAGGCGGCGG AGTCAGCAGT GCCAAGAATA AGACTCACTT CTCAGTGAGG 
CTGCTCAAGT TTTCTCGAGA GAAGAAAGCT GCCAAGACGC TGGGCATCGT GGTGGGTTGC 
TTCGTCCTCT GCTGGCTGCC GTTCTTCCTA GTGATGCCCA TTGGGTCTTT CTTCCCGGAT 
TTCAAGCCTT CGGAAACCGT TTTTAAAATA GTATTTTGGC TCGGGTATCT AAATAGTTGC 
ATCAACCCTA TCATATACCC ATGCTCCAGC CAGGAGTTCA AGAAAGCCTT TCAGAATGTC 
CTGCGAATCC AGTGTCTTCG CAGAAGGCAG TCTTCCAAGC ATGCCCTGGG CTATACCCTG 
CACCCGCCCA GCCAGGCTCT AGAGGGACAG CACAGAGACA TGGTGCGTAT CCCGGTGGGC 
TCGGGAGAGA CTTTCTATAA GATCTCCAAG ACAGATGGAG TCTGTGAATG GAAGTTTTTC 
TCTTCCATGC CCCAGGGATC GGCCAGGATT ACAGTGCCAA AGGACCAATC TGCCTGTACC 
ACAGCCCGGG TGAGAAGTAA AAGCTTTTTG CAGGTCTGCT GCTGTGTGGG GTCCTCGGCC 
CCGCGCCCTG AAGAAAATCA CCAAGTTCCA ACCATTAAGA TCCACACCAT CTCCCTCGGT 
GAAAACGGGG AGGAAGTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adra1a ( XM_006252107.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006252169.1 Rattus norvegicus adrenoceptor alpha 1A (Adra1a), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa12739
Clone ID Related Accession (Same CDS sequence)	XM_006252107.3 , XM_008770744.2 , NM_017191.2
Accession Version	XM_006252107.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1401bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	alpha-1A adrenergic receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006252107.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGCTTC TCTCTGAAAA TGCTTCGGAA GGCTCCAACT GCACCCACCC ACCAGCTCCG 
GTGAACATTT CTAAGGCCAT TCTGCTTGGG GTGATCTTGG GGGGCCTCAT CATTTTCGGA 
GTCCTGGGGA ACATTTTAGT GATCCTCTCA GTGGCCTGTC ATCGGCATCT GCACTCCGTG 
ACTCACTACT ACATTGTCAA CCTGGCTGTG GCAGACCTCC TCCTCACCTC CACTGTGCTG 
CCCTTCTCTG CCATCTTTGA GATCCTGGGC TACTGGGCCT TTGGCAGGGT GTTCTGCAAT 
ATCTGGGCGG CCGTGGACGT CTTATGCTGC ACAGCGTCCA TCATGGGCCT CTGCATCATC 
TCCATCGACC GATACATTGG TGTGAGCTAC CCGCTGCGCT ATCCCACCAT TGTCACCCAG 
AGGAGGGGCG TCAGGGCTCT GCTCTGCGTC TGGGTGCTTT CTTTGGTCAT CTCCATCGGA 
CCCCTGTTCG GCTGGAGGCA GCCGGCTCCA GAGGATGAGA CCATCTGCCA GATCAATGAG 
GAGCCGGGCT ACGTGCTGTT CTCAGCGCTG GGCTCTTTCT ACGTGCCACT GGCCATCATT 
CTGGTTATGT ACTGTCGAGT CTACGTAGTA GCCAAGAGAG AAAGCCGGGG CCTCAAGTCC 
GGCCTCAAGA CGGACAAGTC AGACTCAGAG CAAGTGACGC TCCGCATCCA CCGTAAAAAT 
GTCCCTGCAG AAGGCGGCGG AGTCAGCAGT GCCAAGAATA AGACTCACTT CTCAGTGAGG 
CTGCTCAAGT TTTCTCGAGA GAAGAAAGCT GCCAAGACGC TGGGCATCGT GGTGGGTTGC 
TTCGTCCTCT GCTGGCTGCC GTTCTTCCTA GTGATGCCCA TTGGGTCTTT CTTCCCGGAT 
TTCAAGCCTT CGGAAACCGT TTTTAAAATA GTATTTTGGC TCGGGTATCT AAATAGTTGC 
ATCAACCCTA TCATATACCC ATGCTCCAGC CAGGAGTTCA AGAAAGCCTT TCAGAATGTC 
CTGCGAATCC AGTGTCTTCG CAGAAGGCAG TCTTCCAAGC ATGCCCTGGG CTATACCCTG 
CACCCGCCCA GCCAGGCTCT AGAGGGACAG CACAGAGACA TGGTGCGTAT CCCGGTGGGC 
TCGGGAGAGA CTTTCTATAA GATCTCCAAG ACAGATGGAG TCTGTGAATG GAAGTTTTTC 
TCTTCCATGC CCCAGGGATC GGCCAGGATT ACAGTGCCAA AGGACCAATC TGCCTGTACC 
ACAGCCCGGG TGAGAAGTAA AAGCTTTTTG CAGGTCTGCT GCTGTGTGGG GTCCTCGGCC 
CCGCGCCCTG AAGAAAATCA CCAAGTTCCA ACCATTAAGA TCCACACCAT CTCCCTCGGT 
GAAAACGGGG AGGAAGTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006252169.1
CDS	1065..2465
Translation	MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNVPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTLHPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACTTARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV

Target ORF information:

RefSeq Version	XM_006252107.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adrenoceptor alpha 1A (Adra1a), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006252107.3

ORF Insert Sequence:

ATGGTGCTTC TCTCTGAAAA TGCTTCGGAA GGCTCCAACT GCACCCACCC ACCAGCTCCG 
GTGAACATTT CTAAGGCCAT TCTGCTTGGG GTGATCTTGG GGGGCCTCAT CATTTTCGGA 
GTCCTGGGGA ACATTTTAGT GATCCTCTCA GTGGCCTGTC ATCGGCATCT GCACTCCGTG 
ACTCACTACT ACATTGTCAA CCTGGCTGTG GCAGACCTCC TCCTCACCTC CACTGTGCTG 
CCCTTCTCTG CCATCTTTGA GATCCTGGGC TACTGGGCCT TTGGCAGGGT GTTCTGCAAT 
ATCTGGGCGG CCGTGGACGT CTTATGCTGC ACAGCGTCCA TCATGGGCCT CTGCATCATC 
TCCATCGACC GATACATTGG TGTGAGCTAC CCGCTGCGCT ATCCCACCAT TGTCACCCAG 
AGGAGGGGCG TCAGGGCTCT GCTCTGCGTC TGGGTGCTTT CTTTGGTCAT CTCCATCGGA 
CCCCTGTTCG GCTGGAGGCA GCCGGCTCCA GAGGATGAGA CCATCTGCCA GATCAATGAG 
GAGCCGGGCT ACGTGCTGTT CTCAGCGCTG GGCTCTTTCT ACGTGCCACT GGCCATCATT 
CTGGTTATGT ACTGTCGAGT CTACGTAGTA GCCAAGAGAG AAAGCCGGGG CCTCAAGTCC 
GGCCTCAAGA CGGACAAGTC AGACTCAGAG CAAGTGACGC TCCGCATCCA CCGTAAAAAT 
GTCCCTGCAG AAGGCGGCGG AGTCAGCAGT GCCAAGAATA AGACTCACTT CTCAGTGAGG 
CTGCTCAAGT TTTCTCGAGA GAAGAAAGCT GCCAAGACGC TGGGCATCGT GGTGGGTTGC 
TTCGTCCTCT GCTGGCTGCC GTTCTTCCTA GTGATGCCCA TTGGGTCTTT CTTCCCGGAT 
TTCAAGCCTT CGGAAACCGT TTTTAAAATA GTATTTTGGC TCGGGTATCT AAATAGTTGC 
ATCAACCCTA TCATATACCC ATGCTCCAGC CAGGAGTTCA AGAAAGCCTT TCAGAATGTC 
CTGCGAATCC AGTGTCTTCG CAGAAGGCAG TCTTCCAAGC ATGCCCTGGG CTATACCCTG 
CACCCGCCCA GCCAGGCTCT AGAGGGACAG CACAGAGACA TGGTGCGTAT CCCGGTGGGC 
TCGGGAGAGA CTTTCTATAA GATCTCCAAG ACAGATGGAG TCTGTGAATG GAAGTTTTTC 
TCTTCCATGC CCCAGGGATC GGCCAGGATT ACAGTGCCAA AGGACCAATC TGCCTGTACC 
ACAGCCCGGG TGAGAAGTAA AAGCTTTTTG CAGGTCTGCT GCTGTGTGGG GTCCTCGGCC 
CCGCGCCCTG AAGAAAATCA CCAAGTTCCA ACCATTAAGA TCCACACCAT CTCCCTCGGT 
GAAAACGGGG AGGAAGTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adra1a ( XM_008770744.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008768966.1 Rattus norvegicus adrenoceptor alpha 1A (Adra1a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa12739
Clone ID Related Accession (Same CDS sequence)	XM_006252107.3 , XM_008770744.2 , NM_017191.2
Accession Version	XM_008770744.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1401bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	alpha-1A adrenergic receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008770744.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGCTTC TCTCTGAAAA TGCTTCGGAA GGCTCCAACT GCACCCACCC ACCAGCTCCG 
GTGAACATTT CTAAGGCCAT TCTGCTTGGG GTGATCTTGG GGGGCCTCAT CATTTTCGGA 
GTCCTGGGGA ACATTTTAGT GATCCTCTCA GTGGCCTGTC ATCGGCATCT GCACTCCGTG 
ACTCACTACT ACATTGTCAA CCTGGCTGTG GCAGACCTCC TCCTCACCTC CACTGTGCTG 
CCCTTCTCTG CCATCTTTGA GATCCTGGGC TACTGGGCCT TTGGCAGGGT GTTCTGCAAT 
ATCTGGGCGG CCGTGGACGT CTTATGCTGC ACAGCGTCCA TCATGGGCCT CTGCATCATC 
TCCATCGACC GATACATTGG TGTGAGCTAC CCGCTGCGCT ATCCCACCAT TGTCACCCAG 
AGGAGGGGCG TCAGGGCTCT GCTCTGCGTC TGGGTGCTTT CTTTGGTCAT CTCCATCGGA 
CCCCTGTTCG GCTGGAGGCA GCCGGCTCCA GAGGATGAGA CCATCTGCCA GATCAATGAG 
GAGCCGGGCT ACGTGCTGTT CTCAGCGCTG GGCTCTTTCT ACGTGCCACT GGCCATCATT 
CTGGTTATGT ACTGTCGAGT CTACGTAGTA GCCAAGAGAG AAAGCCGGGG CCTCAAGTCC 
GGCCTCAAGA CGGACAAGTC AGACTCAGAG CAAGTGACGC TCCGCATCCA CCGTAAAAAT 
GTCCCTGCAG AAGGCGGCGG AGTCAGCAGT GCCAAGAATA AGACTCACTT CTCAGTGAGG 
CTGCTCAAGT TTTCTCGAGA GAAGAAAGCT GCCAAGACGC TGGGCATCGT GGTGGGTTGC 
TTCGTCCTCT GCTGGCTGCC GTTCTTCCTA GTGATGCCCA TTGGGTCTTT CTTCCCGGAT 
TTCAAGCCTT CGGAAACCGT TTTTAAAATA GTATTTTGGC TCGGGTATCT AAATAGTTGC 
ATCAACCCTA TCATATACCC ATGCTCCAGC CAGGAGTTCA AGAAAGCCTT TCAGAATGTC 
CTGCGAATCC AGTGTCTTCG CAGAAGGCAG TCTTCCAAGC ATGCCCTGGG CTATACCCTG 
CACCCGCCCA GCCAGGCTCT AGAGGGACAG CACAGAGACA TGGTGCGTAT CCCGGTGGGC 
TCGGGAGAGA CTTTCTATAA GATCTCCAAG ACAGATGGAG TCTGTGAATG GAAGTTTTTC 
TCTTCCATGC CCCAGGGATC GGCCAGGATT ACAGTGCCAA AGGACCAATC TGCCTGTACC 
ACAGCCCGGG TGAGAAGTAA AAGCTTTTTG CAGGTCTGCT GCTGTGTGGG GTCCTCGGCC 
CCGCGCCCTG AAGAAAATCA CCAAGTTCCA ACCATTAAGA TCCACACCAT CTCCCTCGGT 
GAAAACGGGG AGGAAGTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008768966.1
CDS	1065..2465
Translation	MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNVPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTLHPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACTTARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV

Target ORF information:

RefSeq Version	XM_008770744.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adrenoceptor alpha 1A (Adra1a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008770744.2

ORF Insert Sequence:

ATGGTGCTTC TCTCTGAAAA TGCTTCGGAA GGCTCCAACT GCACCCACCC ACCAGCTCCG 
GTGAACATTT CTAAGGCCAT TCTGCTTGGG GTGATCTTGG GGGGCCTCAT CATTTTCGGA 
GTCCTGGGGA ACATTTTAGT GATCCTCTCA GTGGCCTGTC ATCGGCATCT GCACTCCGTG 
ACTCACTACT ACATTGTCAA CCTGGCTGTG GCAGACCTCC TCCTCACCTC CACTGTGCTG 
CCCTTCTCTG CCATCTTTGA GATCCTGGGC TACTGGGCCT TTGGCAGGGT GTTCTGCAAT 
ATCTGGGCGG CCGTGGACGT CTTATGCTGC ACAGCGTCCA TCATGGGCCT CTGCATCATC 
TCCATCGACC GATACATTGG TGTGAGCTAC CCGCTGCGCT ATCCCACCAT TGTCACCCAG 
AGGAGGGGCG TCAGGGCTCT GCTCTGCGTC TGGGTGCTTT CTTTGGTCAT CTCCATCGGA 
CCCCTGTTCG GCTGGAGGCA GCCGGCTCCA GAGGATGAGA CCATCTGCCA GATCAATGAG 
GAGCCGGGCT ACGTGCTGTT CTCAGCGCTG GGCTCTTTCT ACGTGCCACT GGCCATCATT 
CTGGTTATGT ACTGTCGAGT CTACGTAGTA GCCAAGAGAG AAAGCCGGGG CCTCAAGTCC 
GGCCTCAAGA CGGACAAGTC AGACTCAGAG CAAGTGACGC TCCGCATCCA CCGTAAAAAT 
GTCCCTGCAG AAGGCGGCGG AGTCAGCAGT GCCAAGAATA AGACTCACTT CTCAGTGAGG 
CTGCTCAAGT TTTCTCGAGA GAAGAAAGCT GCCAAGACGC TGGGCATCGT GGTGGGTTGC 
TTCGTCCTCT GCTGGCTGCC GTTCTTCCTA GTGATGCCCA TTGGGTCTTT CTTCCCGGAT 
TTCAAGCCTT CGGAAACCGT TTTTAAAATA GTATTTTGGC TCGGGTATCT AAATAGTTGC 
ATCAACCCTA TCATATACCC ATGCTCCAGC CAGGAGTTCA AGAAAGCCTT TCAGAATGTC 
CTGCGAATCC AGTGTCTTCG CAGAAGGCAG TCTTCCAAGC ATGCCCTGGG CTATACCCTG 
CACCCGCCCA GCCAGGCTCT AGAGGGACAG CACAGAGACA TGGTGCGTAT CCCGGTGGGC 
TCGGGAGAGA CTTTCTATAA GATCTCCAAG ACAGATGGAG TCTGTGAATG GAAGTTTTTC 
TCTTCCATGC CCCAGGGATC GGCCAGGATT ACAGTGCCAA AGGACCAATC TGCCTGTACC 
ACAGCCCGGG TGAGAAGTAA AAGCTTTTTG CAGGTCTGCT GCTGTGTGGG GTCCTCGGCC 
CCGCGCCCTG AAGAAAATCA CCAAGTTCCA ACCATTAAGA TCCACACCAT CTCCCTCGGT 
GAAAACGGGG AGGAAGTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adra1a ( XM_006252108.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006252170.1 Rattus norvegicus adrenoceptor alpha 1A (Adra1a), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa36755
Clone ID Related Accession (Same CDS sequence)	XM_006252108.3
Accession Version	XM_006252108.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1308bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	alpha-1A adrenergic receptor isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006252108.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGCTTC TCTCTGAAAA TGCTTCGGAA GGCTCCAACT GCACCCACCC ACCAGCTCCG 
GTGAACATTT CTAAGGCCAT TCTGCTTGGG GTGATCTTGG GGGGCCTCAT CATTTTCGGA 
GTCCTGGGGA ACATTTTAGT GATCCTCTCA GTGGCCTGTC ATCGGCATCT GCACTCCGTG 
ACTCACTACT ACATTGTCAA CCTGGCTGTG GCAGACCTCC TCCTCACCTC CACTGTGCTG 
CCCTTCTCTG CCATCTTTGA GATCCTGGGC TACTGGGCCT TTGGCAGGGT GTTCTGCAAT 
ATCTGGGCGG CCGTGGACGT CTTATGCTGC ACAGCGTCCA TCATGGGCCT CTGCATCATC 
TCCATCGACC GATACATTGG TGTGAGCTAC CCGCTGCGCT ATCCCACCAT TGTCACCCAG 
AGGAGGGGCG TCAGGGCTCT GCTCTGCGTC TGGGTGCTTT CTTTGGTCAT CTCCATCGGA 
CCCCTGTTCG GCTGGAGGCA GCCGGCTCCA GAGGATGAGA CCATCTGCCA GATCAATGAG 
GAGCCGGGCT ACGTGCTGTT CTCAGCGCTG GGCTCTTTCT ACGTGCCACT GGCCATCATT 
CTGGTTATGT ACTGTCGAGT CTACGTAGTA GCCAAGAGAG AAAGCCGGGG CCTCAAGTCC 
GGCCTCAAGA CGGACAAGTC AGACTCAGAG CAAGTGACGC TCCGCATCCA CCGTAAAAAT 
GTCCCTGCAG AAGGCGGCGG AGTCAGCAGT GCCAAGAATA AGACTCACTT CTCAGTGAGG 
CTGCTCAAGT TTTCTCGAGA GAAGAAAGCT GCCAAGACGC TGGGCATCGT GGTGGGTTGC 
TTCGTCCTCT GCTGGCTGCC GTTCTTCCTA GTGATGCCCA TTGGGTCTTT CTTCCCGGAT 
TTCAAGCCTT CGGAAACCGT TTTTAAAATA GTATTTTGGC TCGGGTATCT AAATAGTTGC 
ATCAACCCTA TCATATACCC ATGCTCCAGC CAGGAGTTCA AGAAAGCCTT TCAGAATGTC 
CTGCGAATCC AGTGTCTTCG CAGAAGGCAG TCTTCCAAGC ATGCCCTGGG CTATACCCTG 
CACCCGCCCA GCCAGGCTCT AGAGGGACAG CACAGAGACA TGGGATCGGC CAGGATTACA 
GTGCCAAAGG ACCAATCTGC CTGTACCACA GCCCGGGTGA GAAGTAAAAG CTTTTTGCAG 
GTCTGCTGCT GTGTGGGGTC CTCGGCCCCG CGCCCTGAAG AAAATCACCA AGTTCCAACC 
ATTAAGATCC ACACCATCTC CCTCGGTGAA AACGGGGAGG AAGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006252170.1
CDS	1064..2371
Translation	MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNVPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTLHPPSQALEGQHRDMGSARITVPKDQSACTTARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV

Target ORF information:

RefSeq Version	XM_006252108.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adrenoceptor alpha 1A (Adra1a), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006252108.3

ORF Insert Sequence:

ATGGTGCTTC TCTCTGAAAA TGCTTCGGAA GGCTCCAACT GCACCCACCC ACCAGCTCCG 
GTGAACATTT CTAAGGCCAT TCTGCTTGGG GTGATCTTGG GGGGCCTCAT CATTTTCGGA 
GTCCTGGGGA ACATTTTAGT GATCCTCTCA GTGGCCTGTC ATCGGCATCT GCACTCCGTG 
ACTCACTACT ACATTGTCAA CCTGGCTGTG GCAGACCTCC TCCTCACCTC CACTGTGCTG 
CCCTTCTCTG CCATCTTTGA GATCCTGGGC TACTGGGCCT TTGGCAGGGT GTTCTGCAAT 
ATCTGGGCGG CCGTGGACGT CTTATGCTGC ACAGCGTCCA TCATGGGCCT CTGCATCATC 
TCCATCGACC GATACATTGG TGTGAGCTAC CCGCTGCGCT ATCCCACCAT TGTCACCCAG 
AGGAGGGGCG TCAGGGCTCT GCTCTGCGTC TGGGTGCTTT CTTTGGTCAT CTCCATCGGA 
CCCCTGTTCG GCTGGAGGCA GCCGGCTCCA GAGGATGAGA CCATCTGCCA GATCAATGAG 
GAGCCGGGCT ACGTGCTGTT CTCAGCGCTG GGCTCTTTCT ACGTGCCACT GGCCATCATT 
CTGGTTATGT ACTGTCGAGT CTACGTAGTA GCCAAGAGAG AAAGCCGGGG CCTCAAGTCC 
GGCCTCAAGA CGGACAAGTC AGACTCAGAG CAAGTGACGC TCCGCATCCA CCGTAAAAAT 
GTCCCTGCAG AAGGCGGCGG AGTCAGCAGT GCCAAGAATA AGACTCACTT CTCAGTGAGG 
CTGCTCAAGT TTTCTCGAGA GAAGAAAGCT GCCAAGACGC TGGGCATCGT GGTGGGTTGC 
TTCGTCCTCT GCTGGCTGCC GTTCTTCCTA GTGATGCCCA TTGGGTCTTT CTTCCCGGAT 
TTCAAGCCTT CGGAAACCGT TTTTAAAATA GTATTTTGGC TCGGGTATCT AAATAGTTGC 
ATCAACCCTA TCATATACCC ATGCTCCAGC CAGGAGTTCA AGAAAGCCTT TCAGAATGTC 
CTGCGAATCC AGTGTCTTCG CAGAAGGCAG TCTTCCAAGC ATGCCCTGGG CTATACCCTG 
CACCCGCCCA GCCAGGCTCT AGAGGGACAG CACAGAGACA TGGGATCGGC CAGGATTACA 
GTGCCAAAGG ACCAATCTGC CTGTACCACA GCCCGGGTGA GAAGTAAAAG CTTTTTGCAG 
GTCTGCTGCT GTGTGGGGTC CTCGGCCCCG CGCCCTGAAG AAAATCACCA AGTTCCAACC 
ATTAAGATCC ACACCATCTC CCTCGGTGAA AACGGGGAGG AAGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adra1a ( XM_006252109.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006252171.1 Rattus norvegicus adrenoceptor alpha 1A (Adra1a), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa36756
Clone ID Related Accession (Same CDS sequence)	XM_006252109.3
Accession Version	XM_006252109.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1284bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	alpha-1A adrenergic receptor isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006252109.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGCTTC TCTCTGAAAA TGCTTCGGAA GGCTCCAACT GCACCCACCC ACCAGCTCCG 
GTGAACATTT CTAAGGCCAT TCTGCTTGGG GTGATCTTGG GGGGCCTCAT CATTTTCGGA 
GTCCTGGGGA ACATTTTAGT GATCCTCTCA GTGGCCTGTC ATCGGCATCT GCACTCCGTG 
ACTCACTACT ACATTGTCAA CCTGGCTGTG GCAGACCTCC TCCTCACCTC CACTGTGCTG 
CCCTTCTCTG CCATCTTTGA GATCCTGGGC TACTGGGCCT TTGGCAGGGT GTTCTGCAAT 
ATCTGGGCGG CCGTGGACGT CTTATGCTGC ACAGCGTCCA TCATGGGCCT CTGCATCATC 
TCCATCGACC GATACATTGG TGTGAGCTAC CCGCTGCGCT ATCCCACCAT TGTCACCCAG 
AGGAGGGGCG TCAGGGCTCT GCTCTGCGTC TGGGTGCTTT CTTTGGTCAT CTCCATCGGA 
CCCCTGTTCG GCTGGAGGCA GCCGGCTCCA GAGGATGAGA CCATCTGCCA GATCAATGAG 
GAGCCGGGCT ACGTGCTGTT CTCAGCGCTG GGCTCTTTCT ACGTGCCACT GGCCATCATT 
CTGGTTATGT ACTGTCGAGT CTACGTAGTA GCCAAGAGAG AAAGCCGGGG CCTCAAGTCC 
GGCCTCAAGA CGGACAAGTC AGACTCAGAG CAAGTGACGC TCCGCATCCA CCGTAAAAAT 
GTCCCTGCAG AAGGCGGCGG AGTCAGCAGT GCCAAGAATA AGACTCACTT CTCAGTGAGG 
CTGCTCAAGT TTTCTCGAGA GAAGAAAGCT GCCAAGACGC TGGGCATCGT GGTGGGTTGC 
TTCGTCCTCT GCTGGCTGCC GTTCTTCCTA GTGATGCCCA TTGGGTCTTT CTTCCCGGAT 
TTCAAGCCTT CGGAAACCGT TTTTAAAATA GTATTTTGGC TCGGGTATCT AAATAGTTGC 
ATCAACCCTA TCATATACCC ATGCTCCAGC CAGGAGTTCA AGAAAGCCTT TCAGAATGTC 
CTGCGAATCC AGTGTCTTCG CAGAAGGCAG TCTTCCAAGC ATGCCCTGGG CTATACCCTG 
CACCCGCCCA GCCAGGCTCT AGAGGGACAG CACAGAGACA TGGTGCGTAT CCCGGTGGGC 
TCGGGAGAGA CTTTCTATAA GATCTCCAAG ACAGATGGAG TCTGTGAATG GAAGTTTTTC 
TCTTCCATGC CCCAGGGATC GGCCAGGATT ACAGTGCCAA AGGACCAATC TGCCTGTACC 
ACAGCCCGGG GCTTTTATCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006252171.1
CDS	1065..2348
Translation	MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNVPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTLHPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACTTARGFYP

Target ORF information:

RefSeq Version	XM_006252109.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adrenoceptor alpha 1A (Adra1a), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006252109.3

ORF Insert Sequence:

ATGGTGCTTC TCTCTGAAAA TGCTTCGGAA GGCTCCAACT GCACCCACCC ACCAGCTCCG 
GTGAACATTT CTAAGGCCAT TCTGCTTGGG GTGATCTTGG GGGGCCTCAT CATTTTCGGA 
GTCCTGGGGA ACATTTTAGT GATCCTCTCA GTGGCCTGTC ATCGGCATCT GCACTCCGTG 
ACTCACTACT ACATTGTCAA CCTGGCTGTG GCAGACCTCC TCCTCACCTC CACTGTGCTG 
CCCTTCTCTG CCATCTTTGA GATCCTGGGC TACTGGGCCT TTGGCAGGGT GTTCTGCAAT 
ATCTGGGCGG CCGTGGACGT CTTATGCTGC ACAGCGTCCA TCATGGGCCT CTGCATCATC 
TCCATCGACC GATACATTGG TGTGAGCTAC CCGCTGCGCT ATCCCACCAT TGTCACCCAG 
AGGAGGGGCG TCAGGGCTCT GCTCTGCGTC TGGGTGCTTT CTTTGGTCAT CTCCATCGGA 
CCCCTGTTCG GCTGGAGGCA GCCGGCTCCA GAGGATGAGA CCATCTGCCA GATCAATGAG 
GAGCCGGGCT ACGTGCTGTT CTCAGCGCTG GGCTCTTTCT ACGTGCCACT GGCCATCATT 
CTGGTTATGT ACTGTCGAGT CTACGTAGTA GCCAAGAGAG AAAGCCGGGG CCTCAAGTCC 
GGCCTCAAGA CGGACAAGTC AGACTCAGAG CAAGTGACGC TCCGCATCCA CCGTAAAAAT 
GTCCCTGCAG AAGGCGGCGG AGTCAGCAGT GCCAAGAATA AGACTCACTT CTCAGTGAGG 
CTGCTCAAGT TTTCTCGAGA GAAGAAAGCT GCCAAGACGC TGGGCATCGT GGTGGGTTGC 
TTCGTCCTCT GCTGGCTGCC GTTCTTCCTA GTGATGCCCA TTGGGTCTTT CTTCCCGGAT 
TTCAAGCCTT CGGAAACCGT TTTTAAAATA GTATTTTGGC TCGGGTATCT AAATAGTTGC 
ATCAACCCTA TCATATACCC ATGCTCCAGC CAGGAGTTCA AGAAAGCCTT TCAGAATGTC 
CTGCGAATCC AGTGTCTTCG CAGAAGGCAG TCTTCCAAGC ATGCCCTGGG CTATACCCTG 
CACCCGCCCA GCCAGGCTCT AGAGGGACAG CACAGAGACA TGGTGCGTAT CCCGGTGGGC 
TCGGGAGAGA CTTTCTATAA GATCTCCAAG ACAGATGGAG TCTGTGAATG GAAGTTTTTC 
TCTTCCATGC CCCAGGGATC GGCCAGGATT ACAGTGCCAA AGGACCAATC TGCCTGTACC 
ACAGCCCGGG GCTTTTATCC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adra1a ( XM_006252110.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006252172.1 Rattus norvegicus adrenoceptor alpha 1A (Adra1a), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa36757
Clone ID Related Accession (Same CDS sequence)	XM_006252110.3
Accession Version	XM_006252110.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1137bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	alpha-1A adrenergic receptor isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006252110.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGCTTC TCTCTGAAAA TGCTTCGGAA GGCTCCAACT GCACCCACCC ACCAGCTCCG 
GTGAACATTT CTAAGGCCAT TCTGCTTGGG GTGATCTTGG GGGGCCTCAT CATTTTCGGA 
GTCCTGGGGA ACATTTTAGT GATCCTCTCA GTGGCCTGTC ATCGGCATCT GCACTCCGTG 
ACTCACTACT ACATTGTCAA CCTGGCTGTG GCAGACCTCC TCCTCACCTC CACTGTGCTG 
CCCTTCTCTG CCATCTTTGA GATCCTGGGC TACTGGGCCT TTGGCAGGGT GTTCTGCAAT 
ATCTGGGCGG CCGTGGACGT CTTATGCTGC ACAGCGTCCA TCATGGGCCT CTGCATCATC 
TCCATCGACC GATACATTGG TGTGAGCTAC CCGCTGCGCT ATCCCACCAT TGTCACCCAG 
AGGAGGGGCG TCAGGGCTCT GCTCTGCGTC TGGGTGCTTT CTTTGGTCAT CTCCATCGGA 
CCCCTGTTCG GCTGGAGGCA GCCGGCTCCA GAGGATGAGA CCATCTGCCA GATCAATGAG 
GAGCCGGGCT ACGTGCTGTT CTCAGCGCTG GGCTCTTTCT ACGTGCCACT GGCCATCATT 
CTGGTTATGT ACTGTCGAGT CTACGTAGTA GCCAAGAGAG AAAGCCGGGG CCTCAAGTCC 
GGCCTCAAGA CGGACAAGTC AGACTCAGAG CAAGTGACGC TCCGCATCCA CCGTAAAAAT 
GTCCCTGCAG AAGGCGGCGG AGTCAGCAGT GCCAAGAATA AGACTCACTT CTCAGTGAGG 
CTGCTCAAGT TTTCTCGAGA GAAGAAAGCT GCCAAGACGC TGGGCATCGT GGTGGGTTGC 
TTCGTCCTCT GCTGGCTGCC GTTCTTCCTA GTGATGCCCA TTGGGTCTTT CTTCCCGGAT 
TTCAAGCCTT CGGAAACCGT TTTTAAAATA GTATTTTGGC TCGGGTATCT AAATAGTTGC 
ATCAACCCTA TCATATACCC ATGCTCCAGC CAGGAGTTCA AGAAAGCCTT TCAGAATGTC 
CTGCGAATCC AGTGTCTTCG CAGAAGGCAG TCTTCCAAGC ATGCCCTGGG CTATACCCTG 
CACCCGCCCA GCCAGGCTCT AGAGGGACAG CACAGAGACA TGGGCTTTTA TCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006252172.1
CDS	1053..2189
Translation	MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNVPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTLHPPSQALEGQHRDMGFYP

Target ORF information:

RefSeq Version	XM_006252110.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adrenoceptor alpha 1A (Adra1a), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006252110.3

ORF Insert Sequence:

ATGGTGCTTC TCTCTGAAAA TGCTTCGGAA GGCTCCAACT GCACCCACCC ACCAGCTCCG 
GTGAACATTT CTAAGGCCAT TCTGCTTGGG GTGATCTTGG GGGGCCTCAT CATTTTCGGA 
GTCCTGGGGA ACATTTTAGT GATCCTCTCA GTGGCCTGTC ATCGGCATCT GCACTCCGTG 
ACTCACTACT ACATTGTCAA CCTGGCTGTG GCAGACCTCC TCCTCACCTC CACTGTGCTG 
CCCTTCTCTG CCATCTTTGA GATCCTGGGC TACTGGGCCT TTGGCAGGGT GTTCTGCAAT 
ATCTGGGCGG CCGTGGACGT CTTATGCTGC ACAGCGTCCA TCATGGGCCT CTGCATCATC 
TCCATCGACC GATACATTGG TGTGAGCTAC CCGCTGCGCT ATCCCACCAT TGTCACCCAG 
AGGAGGGGCG TCAGGGCTCT GCTCTGCGTC TGGGTGCTTT CTTTGGTCAT CTCCATCGGA 
CCCCTGTTCG GCTGGAGGCA GCCGGCTCCA GAGGATGAGA CCATCTGCCA GATCAATGAG 
GAGCCGGGCT ACGTGCTGTT CTCAGCGCTG GGCTCTTTCT ACGTGCCACT GGCCATCATT 
CTGGTTATGT ACTGTCGAGT CTACGTAGTA GCCAAGAGAG AAAGCCGGGG CCTCAAGTCC 
GGCCTCAAGA CGGACAAGTC AGACTCAGAG CAAGTGACGC TCCGCATCCA CCGTAAAAAT 
GTCCCTGCAG AAGGCGGCGG AGTCAGCAGT GCCAAGAATA AGACTCACTT CTCAGTGAGG 
CTGCTCAAGT TTTCTCGAGA GAAGAAAGCT GCCAAGACGC TGGGCATCGT GGTGGGTTGC 
TTCGTCCTCT GCTGGCTGCC GTTCTTCCTA GTGATGCCCA TTGGGTCTTT CTTCCCGGAT 
TTCAAGCCTT CGGAAACCGT TTTTAAAATA GTATTTTGGC TCGGGTATCT AAATAGTTGC 
ATCAACCCTA TCATATACCC ATGCTCCAGC CAGGAGTTCA AGAAAGCCTT TCAGAATGTC 
CTGCGAATCC AGTGTCTTCG CAGAAGGCAG TCTTCCAAGC ATGCCCTGGG CTATACCCTG 
CACCCGCCCA GCCAGGCTCT AGAGGGACAG CACAGAGACA TGGGCTTTTA TCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Receptor- and cellular compartment-specific activation of the cAMP/PKA pathway by ?
Cellular signalling4443-50(2018 Jan)
Martin RD,Sun Y,Bourque K,Audet N,Inoue A,Tanny JC,H?bert TE

The water avoidance stress induces bladder pain due to a prolonged alpha1A adrenoceptor stimulation.
Naunyn-Schmiedeberg's archives of pharmacology390(8)839-844(2017 Aug)
Matos R,Serr?o P,Rodriguez L,Birder LA,Cruz F,Charrua A

MRI Assessment of Cardiomyopathy Induced by ?1-Adrenoreceptor Autoantibodies and Protection Through ?3-Adrenoreceptor Overexpression.
Scientific reports743951(2017 Mar)
Vanhoutte L,Guilbaud C,Martherus R,Bouzin C,Gallez B,Dessy C,Balligand JL,Moniotte S,Feron O

Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth.
The Journal of biological chemistry292(6)2065-2079(2017 02)
Cheng Z,Zhu Q,Dee R,Opheim Z,Mack CP,Cyr DM,Taylor JM

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Adra1a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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