Ehd1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ehd1
Entrez Gene ID	293692
Full Name	EH-domain containing 1
Synonyms	RGD1306960
General protein information	Preferred Names EH-domain containing 1 Names EH domain-containing protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q43

mRNA and Protein(s)

mRNA	Protein	Name
NM_001011939.2	NP_001011939.1	EH domain-containing protein 1

Pathways from BioSystems

Homologies

	EHD1	XP_002799535.1
Drosophila melanogaster (fruit fly)	Past1	NP_524332.2
Pan troglodytes (chimpanzee)	EHD1	XP_003951971.1
Canis lupus familiaris (dog)	EHD1	XP_005631565.1
Mus musculus (house mouse)	Ehd1	NP_034249.1
Danio rerio (zebrafish)	ehd1b	NP_001004578.1
Caenorhabditis elegans (roundworm)	rme-1	NP_001024195.1
Rattus norvegicus (Norway rat)	Ehd1	NP_001011939.1
Danio rerio (zebrafish)	ehd1a	NP_998039.1
Arabidopsis thaliana (thale cress)	EHD1	NP_001030731.1
Bos taurus (cattle)	EHD1	NP_001015578.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004593	XP_315231.5
Homo sapiens (human)	EHD1	NP_001269374.1
Oryza sativa (rice)	Os04g0669300	NP_001054202.1
Xenopus tropicalis (tropical clawed frog)	ehd1	NP_001006734.1

Gene Ontology
Bibliography

Related articles in PubMed

The importance of EHD1 in neurite outgrowth contributing to the functional recovery after spinal cord injury.
Wu C, Cui Z, Liu Y, Zhang J, Ding W, Wang S, Bao G, Xu G, Sun Y, Chen J
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience5224-32(2016 Aug)

Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.
Lu Q, Insinna C, Ott C, Stauffer J, Pintado PA, Rahajeng J, Baxa U, Walia V, Cuenca A, Hwang YS, Daar IO, Lopes S, Lippincott-Schwartz J, Jackson PK, Caplan S, Westlake CJ
Nature cell biology17(3)228-240(2015 Mar)

Retromer and sorting nexins in endosomal sorting.
Gallon M, Cullen PJ
Biochemical Society transactions43(1)33-47(2015 Feb)

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)

Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis.
Giridharan SS, Cai B, Vitale N, Naslavsky N, Caplan S
Molecular biology of the cell24(11)1776-90, S1-15(2013 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study demonstrated that EHD1 was up-regulated in rat spinal cord injury model.
Title: The importance of EHD1 in neurite outgrowth contributing to the functional recovery after spinal cord injury.

Rab35 regulates the formation of an EHD1-association site on Arf6-positive endosomes by integrating the functions of two distinct Rab35 effectors for successful neurite outgrowth.
Title: Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth.

EHD1 acts to limit the formation of long, unproductive dynamin helices, thereby promoting synaptic vesicle budding.
Title: Regulation of synaptic vesicle budding and dynamin function by an EHD ATPase.

EHD1 is a synaptic protein that negatively affects exocytosis through binding to snapin
Title: EHD1 is a synaptic protein that modulates exocytosis through binding to snapin.

This results of concluded that, in neurons, EHD1 functions in early endosomes rather than (or possibly in addition to) recycling endosomes. These findings point to the existence of neuronal adaptations of the endosomal system.
Title: Neuronal early endosomes require EHD1 for L1/NgCAM trafficking.

The following Ehd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ehd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01635	NM_001011939.2 Latest version!	Rattus norvegicus EH-domain containing 1 (Ehd1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ehd1 ( NM_001011939.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001011939.1 Rattus norvegicus EH-domain containing 1 (Ehd1), mRNA.

Price & Availability↑

CloneID	ORa01635
Clone ID Related Accession (Same CDS sequence)	NM_001011939.2
Accession Version	NM_001011939.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1605bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	EH domain-containing protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CV120970.1, BC082030.1, CO571196.1 and BQ192279.1. On Oct 22, 2008 this sequence version replaced NM_001011939.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC160908.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTCAGCT GGGTGAGCAA GGATGCCCGC CGCAAGAAGG AGCCGGAGCT CTTCCAGACG 
GTGGCCGAGG GGCTGCGGCA GCTGTACGCG CAGAAGCTGC TGCCGCTGGA GGAGCACTAT 
CGCTTCCACG AGTTCCATTC GCCGGCTCTG GAGGACGCTG ACTTCGACAA CAAACCCATG 
GTGCTCCTGG TCGGCCAGTA CAGCACCGGC AAGACCACCT TCATCCGCCA CTTGATCGAG 
CAGGACTTCC CAGGGATGCG CATCGGGCCG GAGCCCACCA CCGACTCCTT CATCGCAGTC 
ATGCATGGCC CCACCGAGGG CGTGGTGCCC GGCAACGCGC TCGTCGTGGA CCCGCGGCGC 
CCCTTCCGCA AGCTTAACGC CTTCGGCAAC GCCTTCCTCA ACAGGTTCAT GTGTGCACAG 
CTGCCTAACC CAGTATTGGA CAGCATTAGC ATCATTGACA CTCCTGGAAT CCTGTCTGGA 
GAGAAGCAGC GCATCAGCCG AGGTTATGAC TTTGCGGCTG TCCTTGAGTG GTTCGCAGAG 
CGTGTGGACC GCATCATTCT GCTCTTTGAC GCCCACAAGC TAGACATCTC AGATGAATTT 
TCAGAAGTCA TCAAGGCCCT CAAAAATCAC GAGGACAAGA TCCGTGTGGT GCTGAACAAA 
GCTGACCAAA TTGAGACACA GCAGCTGATG CGAGTGTACG GAGCTCTCAT GTGGTCGCTG 
GGGAAGATCA TCAACACCCC TGAGGTGGTC CGTGTCTACA TTGGCTCCTT CTGGTCACAC 
CCACTGCTCA TCCCTGACAA CCGGAAGCTC TTTGAGGCAG AGGAGCAGGA CCTCTTCAAA 
GACATCCAGT CTCTACCAAG AAATGCTGCC CTTAGGAAGC TCAATGACTT AATCAAGCGG 
GCCAGGCTGG CCAAGGTCCA TGCCTACATC ATCAGCTCCC TCAAGAAGGA GATGCCCAAT 
GTCTTTGGGA AAGAGAGCAA GAAGAAAGAG CTGGTGAACA ACTTGGGAGA GATCTACCAG 
AAAATTGAGC GGGAGCACCA GATCTCCTCC GGCGACTTCC CAAGCCTGCG TAAGATGCAG 
GAACTTCTGC AGACGCAGGA CTTCAGCAAG TTCCAGGCCT TGAAGCCCAA GCTGCTGGAT 
ACGGTGGATG ATATGCTGGC CAACGATATA GCTCGGCTGA TGGTGATGGT GCGCCAGGAG 
GAGTCCCTGA TGCCCTCACA GGCTGTGAAG GGTGGTGCTT TTGATGGCAC CATGAATGGG 
CCCTTTGGGC ATGGGTATGG CGAGGGGGCT GGCGAGGGCA TTGATGATGT TGAGTGGGTA 
GTTGGCAAGG ACAAGCCCAC CTATGATGAG ATCTTCTACA CACTGTCTCC TGTCAATGGC 
AAGATCACGG GCGCTAATGC CAAGAAGGAG ATGGTGAAGT CCAAGCTGCC TAACACAGTG 
CTGGGGAAGA TCTGGAAGCT GGCTGATGTG GACAAGGATG GCCTGCTAGA TGACGAGGAG 
TTTGCCCTGG CCAACCACCT TATCAAGGTC AAGCTAGAGG GCCATGAGCT GCCCGCTGAC 
CTTCCTCCAC ATCTCATCCC ACCCTCCAAA CGGAGGCATG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001011939.1
CDS	74..1678
Translation	MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISSGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQAVKGGAFDGTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLIPPSKRRHE

Target ORF information:

RefSeq Version	NM_001011939.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus EH-domain containing 1 (Ehd1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001011939.2

ORF Insert Sequence:

ATGTTCAGCT GGGTGAGCAA GGATGCCCGC CGCAAGAAGG AGCCGGAGCT CTTCCAGACG 
GTGGCCGAGG GGCTGCGGCA GCTGTACGCG CAGAAGCTGC TGCCGCTGGA GGAGCACTAT 
CGCTTCCACG AGTTCCATTC GCCGGCTCTG GAGGACGCTG ACTTCGACAA CAAACCCATG 
GTGCTCCTGG TCGGCCAGTA CAGCACCGGC AAGACCACCT TCATCCGCCA CTTGATCGAG 
CAGGACTTCC CAGGGATGCG CATCGGGCCG GAGCCCACCA CCGACTCCTT CATCGCAGTC 
ATGCATGGCC CCACCGAGGG CGTGGTGCCC GGCAACGCGC TCGTCGTGGA CCCGCGGCGC 
CCCTTCCGCA AGCTTAACGC CTTCGGCAAC GCCTTCCTCA ACAGGTTCAT GTGTGCACAG 
CTGCCTAACC CAGTATTGGA CAGCATTAGC ATCATTGACA CTCCTGGAAT CCTGTCTGGA 
GAGAAGCAGC GCATCAGCCG AGGTTATGAC TTTGCGGCTG TCCTTGAGTG GTTCGCAGAG 
CGTGTGGACC GCATCATTCT GCTCTTTGAC GCCCACAAGC TAGACATCTC AGATGAATTT 
TCAGAAGTCA TCAAGGCCCT CAAAAATCAC GAGGACAAGA TCCGTGTGGT GCTGAACAAA 
GCTGACCAAA TTGAGACACA GCAGCTGATG CGAGTGTACG GAGCTCTCAT GTGGTCGCTG 
GGGAAGATCA TCAACACCCC TGAGGTGGTC CGTGTCTACA TTGGCTCCTT CTGGTCACAC 
CCACTGCTCA TCCCTGACAA CCGGAAGCTC TTTGAGGCAG AGGAGCAGGA CCTCTTCAAA 
GACATCCAGT CTCTACCAAG AAATGCTGCC CTTAGGAAGC TCAATGACTT AATCAAGCGG 
GCCAGGCTGG CCAAGGTCCA TGCCTACATC ATCAGCTCCC TCAAGAAGGA GATGCCCAAT 
GTCTTTGGGA AAGAGAGCAA GAAGAAAGAG CTGGTGAACA ACTTGGGAGA GATCTACCAG 
AAAATTGAGC GGGAGCACCA GATCTCCTCC GGCGACTTCC CAAGCCTGCG TAAGATGCAG 
GAACTTCTGC AGACGCAGGA CTTCAGCAAG TTCCAGGCCT TGAAGCCCAA GCTGCTGGAT 
ACGGTGGATG ATATGCTGGC CAACGATATA GCTCGGCTGA TGGTGATGGT GCGCCAGGAG 
GAGTCCCTGA TGCCCTCACA GGCTGTGAAG GGTGGTGCTT TTGATGGCAC CATGAATGGG 
CCCTTTGGGC ATGGGTATGG CGAGGGGGCT GGCGAGGGCA TTGATGATGT TGAGTGGGTA 
GTTGGCAAGG ACAAGCCCAC CTATGATGAG ATCTTCTACA CACTGTCTCC TGTCAATGGC 
AAGATCACGG GCGCTAATGC CAAGAAGGAG ATGGTGAAGT CCAAGCTGCC TAACACAGTG 
CTGGGGAAGA TCTGGAAGCT GGCTGATGTG GACAAGGATG GCCTGCTAGA TGACGAGGAG 
TTTGCCCTGG CCAACCACCT TATCAAGGTC AAGCTAGAGG GCCATGAGCT GCCCGCTGAC 
CTTCCTCCAC ATCTCATCCC ACCCTCCAAA CGGAGGCATG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The importance of EHD1 in neurite outgrowth contributing to the functional recovery after spinal cord injury.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience5224-32(2016 Aug)
Wu C,Cui Z,Liu Y,Zhang J,Ding W,Wang S,Bao G,Xu G,Sun Y,Chen J

Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.
Nature cell biology17(3)228-240(2015 Mar)
Lu Q,Insinna C,Ott C,Stauffer J,Pintado PA,Rahajeng J,Baxa U,Walia V,Cuenca A,Hwang YS,Daar IO,Lopes S,Lippincott-Schwartz J,Jackson PK,Caplan S,Westlake CJ

Retromer and sorting nexins in endosomal sorting.
Biochemical Society transactions43(1)33-47(2015 Feb)
Gallon M,Cullen PJ

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Science signaling7(354)rs7(2014 Dec)
Guo Z,Neilson LJ,Zhong H,Murray PS,Zanivan S,Zaidel-Bar R

Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis.
Molecular biology of the cell24(11)1776-90, S1-15(2013 Jun)
Giridharan SS,Cai B,Vitale N,Naslavsky N,Caplan S

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Ehd1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報