Pidd1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pidd1
Entrez Gene ID	293625
Full Name	p53-induced death domain protein 1
Synonyms	Lrdd,Pidd
General protein information	Preferred Names p53-induced death domain protein 1 Names p53-induced death domain-containing protein 1 leucine-rich repeats and death domain containing
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q41

mRNA and Protein(s)

mRNA	Protein	Name
NM_001106318.2	NP_001099788.2	p53-induced death domain-containing protein 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LRDD	XP_001149209.2
Mus musculus (house mouse)	Lrdd	NP_073145.1
Rattus norvegicus (Norway rat)	Pidd	NP_001099788.2
Xenopus tropicalis (tropical clawed frog)	pidd	XP_002937546.2
	LOC700580	XP_002808102.1
Canis lupus familiaris (dog)	PIDD	XP_540770.2
Danio rerio (zebrafish)	pidd	XP_699677.5
Homo sapiens (human)	PIDD	NP_665893.2
Rattus norvegicus (Norway rat)	LOC100911519	XP_006230653.1
Bos taurus (cattle)	PIDD	NP_001178416.1
Gallus gallus (chicken)	PIDD	XP_004941518.1

Gene Ontology
Bibliography

Related articles in PubMed

Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop.
Oliver TG, Meylan E, Chang GP, Xue W, Burke JR, Humpton TJ, Hubbard D, Bhutkar A, Jacks T
Molecular cell43(1)57-71(2011 Jul)

Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway.
Tinel A, Janssens S, Lippens S, Cuenin S, Logette E, Jaccard B, Quadroni M, Tschopp J
The EMBO journal26(1)197-208(2007 Jan)

Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.
Berube C, Boucher LM, Ma W, Wakeham A, Salmena L, Hakem R, Yeh WC, Mak TW, Benchimol S
Proceedings of the National Academy of Sciences of the United States of America102(40)14314-20(2005 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Pidd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pidd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13684	NM_001106318.2 Latest version!	Rattus norvegicus p53-induced death domain protein 1 (Pidd1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pidd1 ( NM_001106318.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099788.2 Rattus norvegicus p53-induced death domain protein 1 (Pidd1), mRNA.

Price & Availability↑

CloneID	ORa13684
Clone ID Related Accession (Same CDS sequence)	NM_001106318.2
Accession Version	NM_001106318.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2754bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	p53-induced death domain-containing protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC109542.6. On or before Jul 8, 2012 this sequence version replaced XM_219485.5, XM_001062274.2, NM_001106318.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCAG TGTTGGAGGG GCCGAAGCCA GAGGAAACTG CAGCTGCTGC AGAGGATGCT 
GCAAGACCCA CAGTGGAGGC TGTGGCTTCC AGGCCCGGAG TACCTATTCT CCTGGCTGGG 
AACCAGTTGA ATCTGGACCT ACGCCCTGGG GGCTGCCGTC GGCTGCAGTA CCTGTGTTCC 
CAGCAGCACA CACAGCTGCT GCAAGTGGAG TTTTTGCGGC TCAGCACCCA CGAGGACCCT 
CGACTGCTAG ATGACACCCT AGCCAAGGTT CCGTGGAGTC TACTGCGCCT TCGCTCCCTG 
GTCCTCAAAG GTGGCCAGAG TCGGGGTGCC CTGGGTGCTT GCCTCCATGG TACCCTAACC 
ACTCTGCCTG CTAGCATGAG AGACTTAGCC TGCCTGGCCC ACCTAGACCT GAGCTTCAAC 
AGGCTGGAGA CACTGCCGAC CTGTGTCCTG GAACTGCACA GCTTGGATGC CTTGCTGCTT 
TCTCACAACT GTCTCTCAGA GCTGCCAGAG GCCCTGGGGG CACTGCCTAC CCTCACCTTC 
CTCACTGTGA CACACAACCT CCTGGAAAGA CTACCCCCAA CACTGGGGTC CCTGTCCACC 
CTTCAGCGTC TTGATCTCTC CGAGAACCTT CTAGACACCA TCCCGTCTGA GATTGGAGAC 
CTGAGCAGCC TCAGGGAGCT CAATCTGGCC TCCAACCGGC TGCAGCATCT CCCAGCTTCC 
CTTGCGGGGC TGCGGTCCCT GCGGCTCCTT GTTCTGCACA GCAACCTCTT GACCTCGGTG 
CCCCCTGGCT TGGCCCACCT GCCACTGATC ACTCGGCTTG ACCTGAGGGA CAACCAGCTC 
AGAGACCTAC CTGCCGAGCT ACTAGACGCT CCCTTTGTGC GCCTGCAGGG GAACCCTCTG 
GGCGAGGCCT CTCCTGCACC CCCAAGTCCC CCAGACATTT CCCAGGTTCC AGAAATGCCC 
AGGCTATTCC TGACCTCAGA CTTGGACAGC TTCCTTGTGA CTCCCCATGG CTGTTCTGTG 
ACCCTGGCCT GTGGTGTCCG CCTACAGTTC CCAGCAGGAG CCACCACCAC ACCTATCACC 
ATCCACTATC GACTGTGGTT GCCTGAGCCA GGCCTAGTCT CTCTGGGACC TCATGACTTC 
CTGCTTAGTG GTGTCCTGGA GCTGCAGCCT CATGGGGTGG CTTTCCAGCA GAATGTGAGC 
TTATGGCTGC TCTTTGTCCC CCCACGAGTC CGAGTCCGTC GTTGCCGTGA GGTAGTTGTG 
AGAACACGGA GTGACAACAT CTGGAATGAC CTAGAGACCC ACCTGGAGGA AGAGGCCCCC 
AAGAGGCGTT GGGCTCGCTG CCAGGTGCCC CACTTCTCCT GGTTCCTGGT CGTTTTACGC 
CCAGTATCCA ACACCTGCCT ATTACCACCA GAGGGAGCAC TTCTGTGCTC CTCAGGTCAT 
CCTGGGGTCA AAGTCACTTT TCCCCCTGGG GTCACAGAAG AGCCCCGGCA AGTCTCCATG 
CAGGTAGTGC ATATGGCTGG ACTAGAGCTG AGAGCCCTTC TGGAAGAGTC AGAGGCGGCA 
GTGAGCCCCT TGCTGTGCCT TTCCCAGAGC GGACCCCCCA GCTTCCTACA ACCTGTCACT 
GTGCAGTTGC CCTTGCCCCC CGGTGTTACA GGCTTCAGTC TGGACCGCTC CCACTTACAT 
CTGCTCTACC GAACACCCCT GACAAGCACC TGGGATGACA TCAGCACTCA GGTGGCACTG 
GAATTCACCC ACCTGTACGC ACGCTTCCAG GTCACACACT TCTCCTGGTA CTGGCTCTGG 
TATACCACCA AAACCTGCGT GGGGGGCCTG GCCCGGAAGG CCTGGGAACG GCTGCGGCTG 
CACCGTGTAA ACCTCATTGC ACTGCAGAGG CGCCGAGACC CGGAGCAGGT CCTGCTGCAG 
TGCCTGCCCC GGAGCAAGGT AGATGCCACC CTGAGCCGGC TGCTGGATCG GTACCGTGGC 
CCGGAACCCT CTGAGACTGT GGAGATGTTT GAGGGTGAGA AGTTCTTTGC AGCCTTTGAG 
CGGGGCATCG ATGTAGATGC TGACCGTCCA GACTGTGTGG ATGGCAGAAT CTGTTTTGTC 
TTCTATTCAC ACCTGAAGAA TATGAAGGAG GTATACATTA CCACAGCCTT GGACCGTGAA 
GCTCAGGATG TTCGAGGACA GGTGTCCTTT TATCGGGGTT CACTTCCCAT GGAGGTGCCT 
GAAGAGGCAG AGGCTGCCCG GCGGAGGAAG GGCACAGATG CATTGTGGAT GGCCACCTTG 
CCCATCAAGC TACCGAGACT CCGGGGGGCC CAGGGGAGTG GGCAGGGAAC TGACTTCTCC 
TTGATGCCTC TGAACCTGGG TGATGCAGAA ACTGGATTCC TGACTCAGAG CAACCTGCTG 
AGTGTGGCCT CACGCCTTGG TTCTGACTGG CCGACTGTGG CCCTGCACCT AGGCATGCCC 
TACCGTAAGC TTCAGCGTAT CCGACATGAA TTCAGGGATG ACCTGGATGG GCAGATCCGC 
CACATGCTCT TCTCTTGGGC TGAGAGCCAG ACTGGACAGC CTGGAGCTGT GGGACACCTG 
GTGCAGGCCT TGGAGCAGAG TGACCGGCAG GATGTGGCTG AAGAGGTGCG TGCCATCTTG 
GAACTTGGCC GTCACAAGTA CCAGGACAGC ATTCGGCGCA CAGGGCTGGC CCCTGAGGAT 
TCCACTCTGC CTAGCACCTC AGCTTTACAG AACCCAGAGT CTGCACAGGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099788.2
CDS	79..2832
Translation	MAAVLEGPKPEETAAAAEDAARPTVEAVASRPGVPILLAGNQLNLDLRPGGCRRLQYLCSQQHTQLLQVEFLRLSTHEDPRLLDDTLAKVPWSLLRLRSLVLKGGQSRGALGACLHGTLTTLPASMRDLACLAHLDLSFNRLETLPTCVLELHSLDALLLSHNCLSELPEALGALPTLTFLTVTHNLLERLPPTLGSLSTLQRLDLSENLLDTIPSEIGDLSSLRELNLASNRLQHLPASLAGLRSLRLLVLHSNLLTSVPPGLAHLPLITRLDLRDNQLRDLPAELLDAPFVRLQGNPLGEASPAPPSPPDISQVPEMPRLFLTSDLDSFLVTPHGCSVTLACGVRLQFPAGATTTPITIHYRLWLPEPGLVSLGPHDFLLSGVLELQPHGVAFQQNVSLWLLFVPPRVRVRRCREVVVRTRSDNIWNDLETHLEEEAPKRRWARCQVPHFSWFLVVLRPVSNTCLLPPEGALLCSSGHPGVKVTFPPGVTEEPRQVSMQVVHMAGLELRALLEESEAAVSPLLCLSQSGPPSFLQPVTVQLPLPPGVTGFSLDRSHLHLLYRTPLTSTWDDISTQVALEFTHLYARFQVTHFSWYWLWYTTKTCVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRSKVDATLSRLLDRYRGPEPSETVEMFEGEKFFAAFERGIDVDADRPDCVDGRICFVFYSHLKNMKEVYITTALDREAQDVRGQVSFYRGSLPMEVPEEAEAARRRKGTDALWMATLPIKLPRLRGAQGSGQGTDFSLMPLNLGDAETGFLTQSNLLSVASRLGSDWPTVALHLGMPYRKLQRIRHEFRDDLDGQIRHMLFSWAESQTGQPGAVGHLVQALEQSDRQDVAEEVRAILELGRHKYQDSIRRTGLAPEDSTLPSTSALQNPESAQA

Target ORF information:

RefSeq Version	NM_001106318.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus p53-induced death domain protein 1 (Pidd1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106318.2

ORF Insert Sequence:

ATGGCTGCAG TGTTGGAGGG GCCGAAGCCA GAGGAAACTG CAGCTGCTGC AGAGGATGCT 
GCAAGACCCA CAGTGGAGGC TGTGGCTTCC AGGCCCGGAG TACCTATTCT CCTGGCTGGG 
AACCAGTTGA ATCTGGACCT ACGCCCTGGG GGCTGCCGTC GGCTGCAGTA CCTGTGTTCC 
CAGCAGCACA CACAGCTGCT GCAAGTGGAG TTTTTGCGGC TCAGCACCCA CGAGGACCCT 
CGACTGCTAG ATGACACCCT AGCCAAGGTT CCGTGGAGTC TACTGCGCCT TCGCTCCCTG 
GTCCTCAAAG GTGGCCAGAG TCGGGGTGCC CTGGGTGCTT GCCTCCATGG TACCCTAACC 
ACTCTGCCTG CTAGCATGAG AGACTTAGCC TGCCTGGCCC ACCTAGACCT GAGCTTCAAC 
AGGCTGGAGA CACTGCCGAC CTGTGTCCTG GAACTGCACA GCTTGGATGC CTTGCTGCTT 
TCTCACAACT GTCTCTCAGA GCTGCCAGAG GCCCTGGGGG CACTGCCTAC CCTCACCTTC 
CTCACTGTGA CACACAACCT CCTGGAAAGA CTACCCCCAA CACTGGGGTC CCTGTCCACC 
CTTCAGCGTC TTGATCTCTC CGAGAACCTT CTAGACACCA TCCCGTCTGA GATTGGAGAC 
CTGAGCAGCC TCAGGGAGCT CAATCTGGCC TCCAACCGGC TGCAGCATCT CCCAGCTTCC 
CTTGCGGGGC TGCGGTCCCT GCGGCTCCTT GTTCTGCACA GCAACCTCTT GACCTCGGTG 
CCCCCTGGCT TGGCCCACCT GCCACTGATC ACTCGGCTTG ACCTGAGGGA CAACCAGCTC 
AGAGACCTAC CTGCCGAGCT ACTAGACGCT CCCTTTGTGC GCCTGCAGGG GAACCCTCTG 
GGCGAGGCCT CTCCTGCACC CCCAAGTCCC CCAGACATTT CCCAGGTTCC AGAAATGCCC 
AGGCTATTCC TGACCTCAGA CTTGGACAGC TTCCTTGTGA CTCCCCATGG CTGTTCTGTG 
ACCCTGGCCT GTGGTGTCCG CCTACAGTTC CCAGCAGGAG CCACCACCAC ACCTATCACC 
ATCCACTATC GACTGTGGTT GCCTGAGCCA GGCCTAGTCT CTCTGGGACC TCATGACTTC 
CTGCTTAGTG GTGTCCTGGA GCTGCAGCCT CATGGGGTGG CTTTCCAGCA GAATGTGAGC 
TTATGGCTGC TCTTTGTCCC CCCACGAGTC CGAGTCCGTC GTTGCCGTGA GGTAGTTGTG 
AGAACACGGA GTGACAACAT CTGGAATGAC CTAGAGACCC ACCTGGAGGA AGAGGCCCCC 
AAGAGGCGTT GGGCTCGCTG CCAGGTGCCC CACTTCTCCT GGTTCCTGGT CGTTTTACGC 
CCAGTATCCA ACACCTGCCT ATTACCACCA GAGGGAGCAC TTCTGTGCTC CTCAGGTCAT 
CCTGGGGTCA AAGTCACTTT TCCCCCTGGG GTCACAGAAG AGCCCCGGCA AGTCTCCATG 
CAGGTAGTGC ATATGGCTGG ACTAGAGCTG AGAGCCCTTC TGGAAGAGTC AGAGGCGGCA 
GTGAGCCCCT TGCTGTGCCT TTCCCAGAGC GGACCCCCCA GCTTCCTACA ACCTGTCACT 
GTGCAGTTGC CCTTGCCCCC CGGTGTTACA GGCTTCAGTC TGGACCGCTC CCACTTACAT 
CTGCTCTACC GAACACCCCT GACAAGCACC TGGGATGACA TCAGCACTCA GGTGGCACTG 
GAATTCACCC ACCTGTACGC ACGCTTCCAG GTCACACACT TCTCCTGGTA CTGGCTCTGG 
TATACCACCA AAACCTGCGT GGGGGGCCTG GCCCGGAAGG CCTGGGAACG GCTGCGGCTG 
CACCGTGTAA ACCTCATTGC ACTGCAGAGG CGCCGAGACC CGGAGCAGGT CCTGCTGCAG 
TGCCTGCCCC GGAGCAAGGT AGATGCCACC CTGAGCCGGC TGCTGGATCG GTACCGTGGC 
CCGGAACCCT CTGAGACTGT GGAGATGTTT GAGGGTGAGA AGTTCTTTGC AGCCTTTGAG 
CGGGGCATCG ATGTAGATGC TGACCGTCCA GACTGTGTGG ATGGCAGAAT CTGTTTTGTC 
TTCTATTCAC ACCTGAAGAA TATGAAGGAG GTATACATTA CCACAGCCTT GGACCGTGAA 
GCTCAGGATG TTCGAGGACA GGTGTCCTTT TATCGGGGTT CACTTCCCAT GGAGGTGCCT 
GAAGAGGCAG AGGCTGCCCG GCGGAGGAAG GGCACAGATG CATTGTGGAT GGCCACCTTG 
CCCATCAAGC TACCGAGACT CCGGGGGGCC CAGGGGAGTG GGCAGGGAAC TGACTTCTCC 
TTGATGCCTC TGAACCTGGG TGATGCAGAA ACTGGATTCC TGACTCAGAG CAACCTGCTG 
AGTGTGGCCT CACGCCTTGG TTCTGACTGG CCGACTGTGG CCCTGCACCT AGGCATGCCC 
TACCGTAAGC TTCAGCGTAT CCGACATGAA TTCAGGGATG ACCTGGATGG GCAGATCCGC 
CACATGCTCT TCTCTTGGGC TGAGAGCCAG ACTGGACAGC CTGGAGCTGT GGGACACCTG 
GTGCAGGCCT TGGAGCAGAG TGACCGGCAG GATGTGGCTG AAGAGGTGCG TGCCATCTTG 
GAACTTGGCC GTCACAAGTA CCAGGACAGC ATTCGGCGCA CAGGGCTGGC CCCTGAGGAT 
TCCACTCTGC CTAGCACCTC AGCTTTACAG AACCCAGAGT CTGCACAGGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop.
Molecular cell43(1)57-71(2011 Jul)
Oliver TG,Meylan E,Chang GP,Xue W,Burke JR,Humpton TJ,Hubbard D,Bhutkar A,Jacks T

Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway.
The EMBO journal26(1)197-208(2007 Jan)
Tinel A,Janssens S,Lippens S,Cuenin S,Logette E,Jaccard B,Quadroni M,Tschopp J

Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.
Proceedings of the National Academy of Sciences of the United States of America102(40)14314-20(2005 Oct)
Berube C,Boucher LM,Ma W,Wakeham A,Salmena L,Hakem R,Yeh WC,Mak TW,Benchimol S

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Pidd1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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