Pagr1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pagr1
Entrez Gene ID	293500
Full Name	Paxip1-associated glutamate-rich protein 1
Synonyms	Pa1,RGD1305592
General protein information	Preferred Names Paxip1-associated glutamate-rich protein 1 Names PAXIP1-associated glutamate-rich protein 1 PAXIP1-associated protein 1 PTIP-associated protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q37

mRNA and Protein(s)

mRNA	Protein	Name
NM_001013901.1	NP_001013923.1	PAXIP1-associated glutamate-rich protein 1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex.
Starnes LM, Su D, Pikkupeura LM, Weinert BT, Santos MA, Mund A, Soria R, Cho YW, Pozdnyakova I, Kubec H?jfeldt M, Vala A, Yang W, L?pez-M?ndez B, Lee JE, Peng W, Yuan J, Ge K, Montoya G, Nussenzweig A, Choudhary C, Daniel JA
Genes & development30(2)149-63(2016 Jan)

Loss of function of mouse Pax-Interacting Protein 1-associated glutamate rich protein 1a (Pagr1a) leads to reduced Bmp2 expression and defects in chorion and amnion development.
Kumar A, Lualdi M, Loncarek J, Cho YW, Lee JE, Ge K, Kuehn MR
Developmental dynamics : an official publication of the American Association of Anatomists243(7)937-47(2014 Jul)

UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity.
Wang C, Lee JE, Cho YW, Xiao Y, Jin Q, Liu C, Ge K
Proceedings of the National Academy of Sciences of the United States of America109(38)15324-9(2012 Sep)

The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis.
Shilatifard A
Annual review of biochemistry8165-95(2012)

Accumulation of Pax2 transactivation domain interaction protein (PTIP) at sites of DNA breaks via RNF8-dependent pathway is required for cell survival after DNA damage.
Gong Z, Cho YW, Kim JE, Ge K, Chen J
The Journal of biological chemistry284(11)7284-93(2009 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Pagr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pagr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04151	NM_001013901.1 Latest version!	Rattus norvegicus Paxip1-associated glutamate-rich protein 1 (Pagr1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pagr1 ( NM_001013901.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001013923.1 Rattus norvegicus Paxip1-associated glutamate-rich protein 1 (Pagr1), mRNA.

Price & Availability↑

CloneID	ORa04151
Clone ID Related Accession (Same CDS sequence)	NM_001013901.1
Accession Version	NM_001013901.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 483bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Rattus norvegicus(Norway rat)
Product	PAXIP1-associated glutamate-rich protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC088203.1. On Apr 20, 2005 this sequence version replaced XM_215081.3. ##Evidence-Data-START## Transcript exon combination :: BC088203.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCCCTTG CCCTGGGCCA TGGAACCATT GCAGGCAGCA CAGCGGCGCC TCTGTCTGAA 
GAAGGGGAAG TGACTTCCGG CCTCCAGGCT CTGGCGGTGG AGGACACTGG AGGTCCCTCT 
GTCTCGGCTA GTAAGGCCGA GGAAGAGGGG AAAGGCAGTC AGGAGGAGGC CGGGCGTGAG 
GCATCCAGGG CTGAGGAGGC ACTAGAAGCT TCCAGCGCTG TGAGCGACGA GCGTGCCGAG 
GGAGAATCCG AAGACTGGTG CGTGCCCTGC AGCGACGAGG AGGTGGAGCT GCCGGCCAAT 
GGGCAGTCCT GGATGCCCCC ACCCTCCGAA ATCCAGCGGC TCTATGAACT GCTGGCTACC 
CAAGGTACTC TGGAGCTTCA AGCGGAGATC CTACCCCGCC GGCCGCCTAC TCCTGAGGCC 
CAGAGTGAAG AGGAGAGATC AGATGAGGAG CCAGAGGCCA AAGAGGAGGA GGAGGAAAAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013923.1
CDS	391..873
Translation	MSLALGHGTIAGSTAAPLSEEGEVTSGLQALAVEDTGGPSVSASKAEEEGKGSQEEAGREASRAEEALEASSAVSDERAEGESEDWCVPCSDEEVELPANGQSWMPPPSEIQRLYELLATQGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEK

Target ORF information:

RefSeq Version	NM_001013901.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Paxip1-associated glutamate-rich protein 1 (Pagr1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013901.1

ORF Insert Sequence:

ATGTCCCTTG CCCTGGGCCA TGGAACCATT GCAGGCAGCA CAGCGGCGCC TCTGTCTGAA 
GAAGGGGAAG TGACTTCCGG CCTCCAGGCT CTGGCGGTGG AGGACACTGG AGGTCCCTCT 
GTCTCGGCTA GTAAGGCCGA GGAAGAGGGG AAAGGCAGTC AGGAGGAGGC CGGGCGTGAG 
GCATCCAGGG CTGAGGAGGC ACTAGAAGCT TCCAGCGCTG TGAGCGACGA GCGTGCCGAG 
GGAGAATCCG AAGACTGGTG CGTGCCCTGC AGCGACGAGG AGGTGGAGCT GCCGGCCAAT 
GGGCAGTCCT GGATGCCCCC ACCCTCCGAA ATCCAGCGGC TCTATGAACT GCTGGCTACC 
CAAGGTACTC TGGAGCTTCA AGCGGAGATC CTACCCCGCC GGCCGCCTAC TCCTGAGGCC 
CAGAGTGAAG AGGAGAGATC AGATGAGGAG CCAGAGGCCA AAGAGGAGGA GGAGGAAAAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex.
Genes & development30(2)149-63(2016 Jan)
Starnes LM,Su D,Pikkupeura LM,Weinert BT,Santos MA,Mund A,Soria R,Cho YW,Pozdnyakova I,Kubec H?jfeldt M,Vala A,Yang W,L?pez-M?ndez B,Lee JE,Peng W,Yuan J,Ge K,Montoya G,Nussenzweig A,Choudhary C,Daniel JA

Loss of function of mouse Pax-Interacting Protein 1-associated glutamate rich protein 1a (Pagr1a) leads to reduced Bmp2 expression and defects in chorion and amnion development.
Developmental dynamics : an official publication of the American Association of Anatomists243(7)937-47(2014 Jul)
Kumar A,Lualdi M,Loncarek J,Cho YW,Lee JE,Ge K,Kuehn MR

UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity.
Proceedings of the National Academy of Sciences of the United States of America109(38)15324-9(2012 Sep)
Wang C,Lee JE,Cho YW,Xiao Y,Jin Q,Liu C,Ge K

The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis.
Annual review of biochemistry8165-95(2012)
Shilatifard A

Accumulation of Pax2 transactivation domain interaction protein (PTIP) at sites of DNA breaks via RNF8-dependent pathway is required for cell survival after DNA damage.
The Journal of biological chemistry284(11)7284-93(2009 Mar)
Gong Z,Cho YW,Kim JE,Ge K,Chen J