Cln3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cln3
Entrez Gene ID	293485
Full Name	CLN3, battenin
General protein information	Preferred Names CLN3, battenin Names battenin Cln3p ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) ceroid-lipofuscinosis, neuronal 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q36

mRNA and Protein(s)

mRNA	Protein	Name
XM_008759873.1	XP_008758095.1	battenin isoform X1
XM_008759871.2	XP_008758093.1	battenin isoform X1
XM_008759875.2	XP_008758097.1	battenin isoform X2
XM_008759872.2	XP_008758094.1	battenin isoform X1
NM_001006971.1	NP_001006972.1	battenin

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003934	XP_318386.5
Caenorhabditis elegans (roundworm)	cln-3.3	NP_505237.1
Neurospora crassa	NCU10272	XP_001728107.1
Caenorhabditis elegans (roundworm)	cln-3.1	NP_001256315.1
Eremothecium gossypii	AGOS_AEL171C	NP_984690.1
Canis lupus familiaris (dog)	CLN3	NP_001013435.1
Bos taurus (cattle)	CLN3	NP_001068642.2
Mus musculus (house mouse)	Cln3	NP_034037.3
Rattus norvegicus (Norway rat)	Cln3	NP_001006972.1
Danio rerio (zebrafish)	cln3	NP_001007307.1
Xenopus tropicalis (tropical clawed frog)	cln3	XP_004919824.1
Caenorhabditis elegans (roundworm)	cln-3.2	NP_491556.1
Saccharomyces cerevisiae (baker's yeast)	YHC3	NP_012476.1
Kluyveromyces lactis	KLLA0F01551g	XP_455150.1
Magnaporthe oryzae (rice blast fungus)	MGG_06604	XP_003716923.1
Homo sapiens (human)	CLN3	NP_001035897.1
Drosophila melanogaster (fruit fly)	cln3	NP_649011.1
Schizosaccharomyces pombe (fission yeast)	btn1	NP_593598.1
Neurospora crassa	NCU08408	XP_963280.2

Gene Ontology
Bibliography

Related articles in PubMed

CLN3 deficient cells display defects in the ARF1-Cdc42 pathway and actin-dependent events.
Schultz ML, Tecedor L, Stein CS, Stamnes MA, Davidson BL
PloS one9(5)e96647(2014)

Amlodipine prevents apoptotic cell death by correction of elevated intracellular calcium in a primary neuronal model of Batten disease (CLN3 disease).
Warnock A, Tan L, Li C, An Haack K, Narayan SB, Bennett MJ
Biochemical and biophysical research communications436(4)645-9(2013 Jul)

Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments.
Uusi-Rauva K, Kytt?l? A, van der Kant R, Vesa J, Tanhuanp?? K, Neefjes J, Olkkonen VM, Jalanko A
Cellular and molecular life sciences : CMLS69(12)2075-89(2012 Jun)

Novel interactions of CLN5 support molecular networking between Neuronal Ceroid Lipofuscinosis proteins.
Lyly A, von Schantz C, Heine C, Schmiedt ML, Sipil? T, Jalanko A, Kytt?l? A
BMC cell biology1083(2009 Nov)

Integral and associated lysosomal membrane proteins.
Schr?der B, Wrocklage C, Pan C, J?ger R, K?sters B, Sch?fer H, Els?sser HP, Mann M, Hasilik A
Traffic (Copenhagen, Denmark)8(12)1676-86(2007 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

developed a CLN3 siRNA-inhibited primary rat neuron model to further study etoposide-induced calcium changes and apoptosis in CLN3 disease followed by recovery experiments with amlodipine
Title: Amlodipine prevents apoptotic cell death by correction of elevated intracellular calcium in a primary neuronal model of Batten disease (CLN3 disease).

AP-1 and AP-3 facilitate lysosomal targeting of Batten disease protein CLN3 via its dileucine motif
Title: AP-1 and AP-3 facilitate lysosomal targeting of Batten disease protein CLN3 via its dileucine motif.

The following Cln3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cln3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa10666	NM_001006971.1 Latest version!	Rattus norvegicus CLN3 lysosomal/endosomal transmembrane protein, battenin (Cln3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa10666	XM_008759871.2 Latest version!	Rattus norvegicus ceroid-lipofuscinosis, neuronal 3 (Cln3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa10666	XM_008759873.1 Latest version!	Rattus norvegicus ceroid-lipofuscinosis, neuronal 3 (Cln3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa10666	XM_008759872.2 Latest version!	Rattus norvegicus ceroid-lipofuscinosis, neuronal 3 (Cln3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa45118	XM_008759875.2 Latest version!	Rattus norvegicus ceroid-lipofuscinosis, neuronal 3 (Cln3), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cln3 ( NM_001006971.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001006972.1 Rattus norvegicus CLN3 lysosomal/endosomal transmembrane protein, battenin (Cln3), mRNA.

Price & Availability↑

CloneID	ORa10666
Clone ID Related Accession (Same CDS sequence)	XM_008759873.1 , XM_008759871.2 , XM_008759872.2 , NM_001006971.1
Accession Version	NM_001006971.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1317bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-15
Organism	Rattus norvegicus(Norway rat)
Product	battenin
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083704.1. On Nov 22, 2004 this sequence version replaced XM_215084.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC083704.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGAAGCT CTGAGAGCTC GTGGAGGCGC CTTGAGGATT CTGAGAGGGA GGAGACCGAC 
TCAGAGCCCC AAACCCCTCC GTTGGATAAT CTAAGTGTCC TTTGGAAGAA TGCGGTGGGC 
TTCTGGATCT TGGGGCTTTG CAACAACTTC TCATATGTGG TGATGCTGAG CGCTGCCCAT 
GACATCCTTA AGCAGGAGCA GGCATCTGGA AACCAGAGCC ATGTGGAACC AGGCCCAACA 
CCCATGCCCC ATAACAGCTC ATCTCGATTT GATTGCAATT CAATCTCCAC AGCTGCGGTG 
CTCCTAGCAG ACATCCTTCC CACCCTTGTC ATCAAACTCC TGGCTCCTCT TGGCCTTCAT 
TTGCTGCCTT ACAGCCCCCG GGTGCTTGTC AGTGGAGTCT GTTCTGCTGG AAGCTTTGTT 
CTGGTTGCCT TTTCTCAATC AGTGGGGTTA AGCCTGTGTG GAGTGGTTTT GGCCAGCATC 
TCATCAGGTC TAGGGGAGGT CACCTTCCTT TCACTGACTG CCTTCTACCC CAGTGCTGTG 
ATCTCATGGT GGTCTTCAGG AACTGGGGGT GCAGGGCTTC TTGGATCGCT GTCATACCTG 
GGGCTCACCC AGGCTGGCCT CTCCCCGCAG CACACCCTAC TTTCTATGCT GGGGATCCCT 
GTTCTGATGC TAGCCAGCTA TTTCTTGCTG CTCACATCTC CTGAACCCCT GGACCCTGGA 
GGGCAAGACG AGGCAGAGAC TGCTGCCCGG CAGCCTCTCA TAGGCACCGA GACCCCAGAG 
TCTAGGCCAG GTACCAGCTG GGACCTCTCT CTCCAGGAAA GGTGGACAGT GTTCAAGGGC 
CTCTTGCGAT ACATCATCCC TCTGGTGCTG GTCTACTTTG CAGAATACTT TATCAACCAG 
GGGCTTTTTG AGCTCCTGTT TTTCCGGAAC ACATCCTTAA GTCATGCTCA GCAGTACCGA 
TGGTACCAGA TGCTATACCA GGCTGGTGTG TTCGCTTCCC GCTCTTCTCT CCAGTGTTGC 
CGAATCCGGT TCACCTGGAT CCTAGCCCTG CTCCAGTGCC TCAACCTGGC CTTCCTGCTG 
GCAGATGTAT GCTTGACCTT CCTGCCCAGC ATCTACCTCA TCTTCATCGT CATTCTGTAT 
GAAGGGCTTC TGGGCGGGGC CGCTTACGTG AATACCTTCC ACAACATTGC CCTGGAGACC 
AGTGACAAGC ACCGAGAGTT TGCCATGGAA GCTGCCTGCA TTTCTGACAC CTTGGGAATC 
TCCCTGTCAG GGGTCCTGGC CTTGCCTCTG CATGACTTCC TCTGCCACCT CCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001006972.1
CDS	157..1473
Translation	MGSSESSWRRLEDSEREETDSEPQTPPLDNLSVLWKNAVGFWILGLCNNFSYVVMLSAAHDILKQEQASGNQSHVEPGPTPMPHNSSSRFDCNSISTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGVCSAGSFVLVAFSQSVGLSLCGVVLASISSGLGEVTFLSLTAFYPSAVISWWSSGTGGAGLLGSLSYLGLTQAGLSPQHTLLSMLGIPVLMLASYFLLLTSPEPLDPGGQDEAETAARQPLIGTETPESRPGTSWDLSLQERWTVFKGLLRYIIPLVLVYFAEYFINQGLFELLFFRNTSLSHAQQYRWYQMLYQAGVFASRSSLQCCRIRFTWILALLQCLNLAFLLADVCLTFLPSIYLIFIVILYEGLLGGAAYVNTFHNIALETSDKHREFAMEAACISDTLGISLSGVLALPLHDFLCHLP

Target ORF information:

RefSeq Version	NM_001006971.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CLN3 lysosomal/endosomal transmembrane protein, battenin (Cln3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001006971.1

ORF Insert Sequence:

ATGGGAAGCT CTGAGAGCTC GTGGAGGCGC CTTGAGGATT CTGAGAGGGA GGAGACCGAC 
TCAGAGCCCC AAACCCCTCC GTTGGATAAT CTAAGTGTCC TTTGGAAGAA TGCGGTGGGC 
TTCTGGATCT TGGGGCTTTG CAACAACTTC TCATATGTGG TGATGCTGAG CGCTGCCCAT 
GACATCCTTA AGCAGGAGCA GGCATCTGGA AACCAGAGCC ATGTGGAACC AGGCCCAACA 
CCCATGCCCC ATAACAGCTC ATCTCGATTT GATTGCAATT CAATCTCCAC AGCTGCGGTG 
CTCCTAGCAG ACATCCTTCC CACCCTTGTC ATCAAACTCC TGGCTCCTCT TGGCCTTCAT 
TTGCTGCCTT ACAGCCCCCG GGTGCTTGTC AGTGGAGTCT GTTCTGCTGG AAGCTTTGTT 
CTGGTTGCCT TTTCTCAATC AGTGGGGTTA AGCCTGTGTG GAGTGGTTTT GGCCAGCATC 
TCATCAGGTC TAGGGGAGGT CACCTTCCTT TCACTGACTG CCTTCTACCC CAGTGCTGTG 
ATCTCATGGT GGTCTTCAGG AACTGGGGGT GCAGGGCTTC TTGGATCGCT GTCATACCTG 
GGGCTCACCC AGGCTGGCCT CTCCCCGCAG CACACCCTAC TTTCTATGCT GGGGATCCCT 
GTTCTGATGC TAGCCAGCTA TTTCTTGCTG CTCACATCTC CTGAACCCCT GGACCCTGGA 
GGGCAAGACG AGGCAGAGAC TGCTGCCCGG CAGCCTCTCA TAGGCACCGA GACCCCAGAG 
TCTAGGCCAG GTACCAGCTG GGACCTCTCT CTCCAGGAAA GGTGGACAGT GTTCAAGGGC 
CTCTTGCGAT ACATCATCCC TCTGGTGCTG GTCTACTTTG CAGAATACTT TATCAACCAG 
GGGCTTTTTG AGCTCCTGTT TTTCCGGAAC ACATCCTTAA GTCATGCTCA GCAGTACCGA 
TGGTACCAGA TGCTATACCA GGCTGGTGTG TTCGCTTCCC GCTCTTCTCT CCAGTGTTGC 
CGAATCCGGT TCACCTGGAT CCTAGCCCTG CTCCAGTGCC TCAACCTGGC CTTCCTGCTG 
GCAGATGTAT GCTTGACCTT CCTGCCCAGC ATCTACCTCA TCTTCATCGT CATTCTGTAT 
GAAGGGCTTC TGGGCGGGGC CGCTTACGTG AATACCTTCC ACAACATTGC CCTGGAGACC 
AGTGACAAGC ACCGAGAGTT TGCCATGGAA GCTGCCTGCA TTTCTGACAC CTTGGGAATC 
TCCCTGTCAG GGGTCCTGGC CTTGCCTCTG CATGACTTCC TCTGCCACCT CCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cln3 ( XM_008759873.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008758095.1 Rattus norvegicus ceroid-lipofuscinosis, neuronal 3 (Cln3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa10666
Clone ID Related Accession (Same CDS sequence)	XM_008759873.1 , XM_008759871.2 , XM_008759872.2 , NM_001006971.1
Accession Version	XM_008759873.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1317bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	battenin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAAGCT CTGAGAGCTC GTGGAGGCGC CTTGAGGATT CTGAGAGGGA GGAGACCGAC 
TCAGAGCCCC AAACCCCTCC GTTGGATAAT CTAAGTGTCC TTTGGAAGAA TGCGGTGGGC 
TTCTGGATCT TGGGGCTTTG CAACAACTTC TCATATGTGG TGATGCTGAG CGCTGCCCAT 
GACATCCTTA AGCAGGAGCA GGCATCTGGA AACCAGAGCC ATGTGGAACC AGGCCCAACA 
CCCATGCCCC ATAACAGCTC ATCTCGATTT GATTGCAATT CAATCTCCAC AGCTGCGGTG 
CTCCTAGCAG ACATCCTTCC CACCCTTGTC ATCAAACTCC TGGCTCCTCT TGGCCTTCAT 
TTGCTGCCTT ACAGCCCCCG GGTGCTTGTC AGTGGAGTCT GTTCTGCTGG AAGCTTTGTT 
CTGGTTGCCT TTTCTCAATC AGTGGGGTTA AGCCTGTGTG GAGTGGTTTT GGCCAGCATC 
TCATCAGGTC TAGGGGAGGT CACCTTCCTT TCACTGACTG CCTTCTACCC CAGTGCTGTG 
ATCTCATGGT GGTCTTCAGG AACTGGGGGT GCAGGGCTTC TTGGATCGCT GTCATACCTG 
GGGCTCACCC AGGCTGGCCT CTCCCCGCAG CACACCCTAC TTTCTATGCT GGGGATCCCT 
GTTCTGATGC TAGCCAGCTA TTTCTTGCTG CTCACATCTC CTGAACCCCT GGACCCTGGA 
GGGCAAGACG AGGCAGAGAC TGCTGCCCGG CAGCCTCTCA TAGGCACCGA GACCCCAGAG 
TCTAGGCCAG GTACCAGCTG GGACCTCTCT CTCCAGGAAA GGTGGACAGT GTTCAAGGGC 
CTCTTGCGAT ACATCATCCC TCTGGTGCTG GTCTACTTTG CAGAATACTT TATCAACCAG 
GGGCTTTTTG AGCTCCTGTT TTTCCGGAAC ACATCCTTAA GTCATGCTCA GCAGTACCGA 
TGGTACCAGA TGCTATACCA GGCTGGTGTG TTCGCTTCCC GCTCTTCTCT CCAGTGTTGC 
CGAATCCGGT TCACCTGGAT CCTAGCCCTG CTCCAGTGCC TCAACCTGGC CTTCCTGCTG 
GCAGATGTAT GCTTGACCTT CCTGCCCAGC ATCTACCTCA TCTTCATCGT CATTCTGTAT 
GAAGGGCTTC TGGGCGGGGC CGCTTACGTG AATACCTTCC ACAACATTGC CCTGGAGACC 
AGTGACAAGC ACCGAGAGTT TGCCATGGAA GCTGCCTGCA TTTCTGACAC CTTGGGAATC 
TCCCTGTCAG GGGTCCTGGC CTTGCCTCTG CATGACTTCC TCTGCCACCT CCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008758095.1
CDS	534..1850
Translation	MGSSESSWRRLEDSEREETDSEPQTPPLDNLSVLWKNAVGFWILGLCNNFSYVVMLSAAHDILKQEQASGNQSHVEPGPTPMPHNSSSRFDCNSISTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGVCSAGSFVLVAFSQSVGLSLCGVVLASISSGLGEVTFLSLTAFYPSAVISWWSSGTGGAGLLGSLSYLGLTQAGLSPQHTLLSMLGIPVLMLASYFLLLTSPEPLDPGGQDEAETAARQPLIGTETPESRPGTSWDLSLQERWTVFKGLLRYIIPLVLVYFAEYFINQGLFELLFFRNTSLSHAQQYRWYQMLYQAGVFASRSSLQCCRIRFTWILALLQCLNLAFLLADVCLTFLPSIYLIFIVILYEGLLGGAAYVNTFHNIALETSDKHREFAMEAACISDTLGISLSGVLALPLHDFLCHLP

Target ORF information:

RefSeq Version	XM_008759873.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ceroid-lipofuscinosis, neuronal 3 (Cln3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759873.1

ORF Insert Sequence:

ATGGGAAGCT CTGAGAGCTC GTGGAGGCGC CTTGAGGATT CTGAGAGGGA GGAGACCGAC 
TCAGAGCCCC AAACCCCTCC GTTGGATAAT CTAAGTGTCC TTTGGAAGAA TGCGGTGGGC 
TTCTGGATCT TGGGGCTTTG CAACAACTTC TCATATGTGG TGATGCTGAG CGCTGCCCAT 
GACATCCTTA AGCAGGAGCA GGCATCTGGA AACCAGAGCC ATGTGGAACC AGGCCCAACA 
CCCATGCCCC ATAACAGCTC ATCTCGATTT GATTGCAATT CAATCTCCAC AGCTGCGGTG 
CTCCTAGCAG ACATCCTTCC CACCCTTGTC ATCAAACTCC TGGCTCCTCT TGGCCTTCAT 
TTGCTGCCTT ACAGCCCCCG GGTGCTTGTC AGTGGAGTCT GTTCTGCTGG AAGCTTTGTT 
CTGGTTGCCT TTTCTCAATC AGTGGGGTTA AGCCTGTGTG GAGTGGTTTT GGCCAGCATC 
TCATCAGGTC TAGGGGAGGT CACCTTCCTT TCACTGACTG CCTTCTACCC CAGTGCTGTG 
ATCTCATGGT GGTCTTCAGG AACTGGGGGT GCAGGGCTTC TTGGATCGCT GTCATACCTG 
GGGCTCACCC AGGCTGGCCT CTCCCCGCAG CACACCCTAC TTTCTATGCT GGGGATCCCT 
GTTCTGATGC TAGCCAGCTA TTTCTTGCTG CTCACATCTC CTGAACCCCT GGACCCTGGA 
GGGCAAGACG AGGCAGAGAC TGCTGCCCGG CAGCCTCTCA TAGGCACCGA GACCCCAGAG 
TCTAGGCCAG GTACCAGCTG GGACCTCTCT CTCCAGGAAA GGTGGACAGT GTTCAAGGGC 
CTCTTGCGAT ACATCATCCC TCTGGTGCTG GTCTACTTTG CAGAATACTT TATCAACCAG 
GGGCTTTTTG AGCTCCTGTT TTTCCGGAAC ACATCCTTAA GTCATGCTCA GCAGTACCGA 
TGGTACCAGA TGCTATACCA GGCTGGTGTG TTCGCTTCCC GCTCTTCTCT CCAGTGTTGC 
CGAATCCGGT TCACCTGGAT CCTAGCCCTG CTCCAGTGCC TCAACCTGGC CTTCCTGCTG 
GCAGATGTAT GCTTGACCTT CCTGCCCAGC ATCTACCTCA TCTTCATCGT CATTCTGTAT 
GAAGGGCTTC TGGGCGGGGC CGCTTACGTG AATACCTTCC ACAACATTGC CCTGGAGACC 
AGTGACAAGC ACCGAGAGTT TGCCATGGAA GCTGCCTGCA TTTCTGACAC CTTGGGAATC 
TCCCTGTCAG GGGTCCTGGC CTTGCCTCTG CATGACTTCC TCTGCCACCT CCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cln3 ( XM_008759871.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008758093.1 Rattus norvegicus ceroid-lipofuscinosis, neuronal 3 (Cln3), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa10666
Clone ID Related Accession (Same CDS sequence)	XM_008759873.1 , XM_008759871.2 , XM_008759872.2 , NM_001006971.1
Accession Version	XM_008759871.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1317bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	battenin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008759871.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAAGCT CTGAGAGCTC GTGGAGGCGC CTTGAGGATT CTGAGAGGGA GGAGACCGAC 
TCAGAGCCCC AAACCCCTCC GTTGGATAAT CTAAGTGTCC TTTGGAAGAA TGCGGTGGGC 
TTCTGGATCT TGGGGCTTTG CAACAACTTC TCATATGTGG TGATGCTGAG CGCTGCCCAT 
GACATCCTTA AGCAGGAGCA GGCATCTGGA AACCAGAGCC ATGTGGAACC AGGCCCAACA 
CCCATGCCCC ATAACAGCTC ATCTCGATTT GATTGCAATT CAATCTCCAC AGCTGCGGTG 
CTCCTAGCAG ACATCCTTCC CACCCTTGTC ATCAAACTCC TGGCTCCTCT TGGCCTTCAT 
TTGCTGCCTT ACAGCCCCCG GGTGCTTGTC AGTGGAGTCT GTTCTGCTGG AAGCTTTGTT 
CTGGTTGCCT TTTCTCAATC AGTGGGGTTA AGCCTGTGTG GAGTGGTTTT GGCCAGCATC 
TCATCAGGTC TAGGGGAGGT CACCTTCCTT TCACTGACTG CCTTCTACCC CAGTGCTGTG 
ATCTCATGGT GGTCTTCAGG AACTGGGGGT GCAGGGCTTC TTGGATCGCT GTCATACCTG 
GGGCTCACCC AGGCTGGCCT CTCCCCGCAG CACACCCTAC TTTCTATGCT GGGGATCCCT 
GTTCTGATGC TAGCCAGCTA TTTCTTGCTG CTCACATCTC CTGAACCCCT GGACCCTGGA 
GGGCAAGACG AGGCAGAGAC TGCTGCCCGG CAGCCTCTCA TAGGCACCGA GACCCCAGAG 
TCTAGGCCAG GTACCAGCTG GGACCTCTCT CTCCAGGAAA GGTGGACAGT GTTCAAGGGC 
CTCTTGCGAT ACATCATCCC TCTGGTGCTG GTCTACTTTG CAGAATACTT TATCAACCAG 
GGGCTTTTTG AGCTCCTGTT TTTCCGGAAC ACATCCTTAA GTCATGCTCA GCAGTACCGA 
TGGTACCAGA TGCTATACCA GGCTGGTGTG TTCGCTTCCC GCTCTTCTCT CCAGTGTTGC 
CGAATCCGGT TCACCTGGAT CCTAGCCCTG CTCCAGTGCC TCAACCTGGC CTTCCTGCTG 
GCAGATGTAT GCTTGACCTT CCTGCCCAGC ATCTACCTCA TCTTCATCGT CATTCTGTAT 
GAAGGGCTTC TGGGCGGGGC CGCTTACGTG AATACCTTCC ACAACATTGC CCTGGAGACC 
AGTGACAAGC ACCGAGAGTT TGCCATGGAA GCTGCCTGCA TTTCTGACAC CTTGGGAATC 
TCCCTGTCAG GGGTCCTGGC CTTGCCTCTG CATGACTTCC TCTGCCACCT CCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008758093.1
CDS	959..2275
Translation	MGSSESSWRRLEDSEREETDSEPQTPPLDNLSVLWKNAVGFWILGLCNNFSYVVMLSAAHDILKQEQASGNQSHVEPGPTPMPHNSSSRFDCNSISTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGVCSAGSFVLVAFSQSVGLSLCGVVLASISSGLGEVTFLSLTAFYPSAVISWWSSGTGGAGLLGSLSYLGLTQAGLSPQHTLLSMLGIPVLMLASYFLLLTSPEPLDPGGQDEAETAARQPLIGTETPESRPGTSWDLSLQERWTVFKGLLRYIIPLVLVYFAEYFINQGLFELLFFRNTSLSHAQQYRWYQMLYQAGVFASRSSLQCCRIRFTWILALLQCLNLAFLLADVCLTFLPSIYLIFIVILYEGLLGGAAYVNTFHNIALETSDKHREFAMEAACISDTLGISLSGVLALPLHDFLCHLP

Target ORF information:

RefSeq Version	XM_008759871.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ceroid-lipofuscinosis, neuronal 3 (Cln3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759871.2

ORF Insert Sequence:

ATGGGAAGCT CTGAGAGCTC GTGGAGGCGC CTTGAGGATT CTGAGAGGGA GGAGACCGAC 
TCAGAGCCCC AAACCCCTCC GTTGGATAAT CTAAGTGTCC TTTGGAAGAA TGCGGTGGGC 
TTCTGGATCT TGGGGCTTTG CAACAACTTC TCATATGTGG TGATGCTGAG CGCTGCCCAT 
GACATCCTTA AGCAGGAGCA GGCATCTGGA AACCAGAGCC ATGTGGAACC AGGCCCAACA 
CCCATGCCCC ATAACAGCTC ATCTCGATTT GATTGCAATT CAATCTCCAC AGCTGCGGTG 
CTCCTAGCAG ACATCCTTCC CACCCTTGTC ATCAAACTCC TGGCTCCTCT TGGCCTTCAT 
TTGCTGCCTT ACAGCCCCCG GGTGCTTGTC AGTGGAGTCT GTTCTGCTGG AAGCTTTGTT 
CTGGTTGCCT TTTCTCAATC AGTGGGGTTA AGCCTGTGTG GAGTGGTTTT GGCCAGCATC 
TCATCAGGTC TAGGGGAGGT CACCTTCCTT TCACTGACTG CCTTCTACCC CAGTGCTGTG 
ATCTCATGGT GGTCTTCAGG AACTGGGGGT GCAGGGCTTC TTGGATCGCT GTCATACCTG 
GGGCTCACCC AGGCTGGCCT CTCCCCGCAG CACACCCTAC TTTCTATGCT GGGGATCCCT 
GTTCTGATGC TAGCCAGCTA TTTCTTGCTG CTCACATCTC CTGAACCCCT GGACCCTGGA 
GGGCAAGACG AGGCAGAGAC TGCTGCCCGG CAGCCTCTCA TAGGCACCGA GACCCCAGAG 
TCTAGGCCAG GTACCAGCTG GGACCTCTCT CTCCAGGAAA GGTGGACAGT GTTCAAGGGC 
CTCTTGCGAT ACATCATCCC TCTGGTGCTG GTCTACTTTG CAGAATACTT TATCAACCAG 
GGGCTTTTTG AGCTCCTGTT TTTCCGGAAC ACATCCTTAA GTCATGCTCA GCAGTACCGA 
TGGTACCAGA TGCTATACCA GGCTGGTGTG TTCGCTTCCC GCTCTTCTCT CCAGTGTTGC 
CGAATCCGGT TCACCTGGAT CCTAGCCCTG CTCCAGTGCC TCAACCTGGC CTTCCTGCTG 
GCAGATGTAT GCTTGACCTT CCTGCCCAGC ATCTACCTCA TCTTCATCGT CATTCTGTAT 
GAAGGGCTTC TGGGCGGGGC CGCTTACGTG AATACCTTCC ACAACATTGC CCTGGAGACC 
AGTGACAAGC ACCGAGAGTT TGCCATGGAA GCTGCCTGCA TTTCTGACAC CTTGGGAATC 
TCCCTGTCAG GGGTCCTGGC CTTGCCTCTG CATGACTTCC TCTGCCACCT CCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cln3 ( XM_008759872.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008758094.1 Rattus norvegicus ceroid-lipofuscinosis, neuronal 3 (Cln3), transcript variant X1, mRNA.

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CloneID	ORa10666
Clone ID Related Accession (Same CDS sequence)	XM_008759873.1 , XM_008759871.2 , XM_008759872.2 , NM_001006971.1
Accession Version	XM_008759872.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1317bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	battenin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008759872.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAAGCT CTGAGAGCTC GTGGAGGCGC CTTGAGGATT CTGAGAGGGA GGAGACCGAC 
TCAGAGCCCC AAACCCCTCC GTTGGATAAT CTAAGTGTCC TTTGGAAGAA TGCGGTGGGC 
TTCTGGATCT TGGGGCTTTG CAACAACTTC TCATATGTGG TGATGCTGAG CGCTGCCCAT 
GACATCCTTA AGCAGGAGCA GGCATCTGGA AACCAGAGCC ATGTGGAACC AGGCCCAACA 
CCCATGCCCC ATAACAGCTC ATCTCGATTT GATTGCAATT CAATCTCCAC AGCTGCGGTG 
CTCCTAGCAG ACATCCTTCC CACCCTTGTC ATCAAACTCC TGGCTCCTCT TGGCCTTCAT 
TTGCTGCCTT ACAGCCCCCG GGTGCTTGTC AGTGGAGTCT GTTCTGCTGG AAGCTTTGTT 
CTGGTTGCCT TTTCTCAATC AGTGGGGTTA AGCCTGTGTG GAGTGGTTTT GGCCAGCATC 
TCATCAGGTC TAGGGGAGGT CACCTTCCTT TCACTGACTG CCTTCTACCC CAGTGCTGTG 
ATCTCATGGT GGTCTTCAGG AACTGGGGGT GCAGGGCTTC TTGGATCGCT GTCATACCTG 
GGGCTCACCC AGGCTGGCCT CTCCCCGCAG CACACCCTAC TTTCTATGCT GGGGATCCCT 
GTTCTGATGC TAGCCAGCTA TTTCTTGCTG CTCACATCTC CTGAACCCCT GGACCCTGGA 
GGGCAAGACG AGGCAGAGAC TGCTGCCCGG CAGCCTCTCA TAGGCACCGA GACCCCAGAG 
TCTAGGCCAG GTACCAGCTG GGACCTCTCT CTCCAGGAAA GGTGGACAGT GTTCAAGGGC 
CTCTTGCGAT ACATCATCCC TCTGGTGCTG GTCTACTTTG CAGAATACTT TATCAACCAG 
GGGCTTTTTG AGCTCCTGTT TTTCCGGAAC ACATCCTTAA GTCATGCTCA GCAGTACCGA 
TGGTACCAGA TGCTATACCA GGCTGGTGTG TTCGCTTCCC GCTCTTCTCT CCAGTGTTGC 
CGAATCCGGT TCACCTGGAT CCTAGCCCTG CTCCAGTGCC TCAACCTGGC CTTCCTGCTG 
GCAGATGTAT GCTTGACCTT CCTGCCCAGC ATCTACCTCA TCTTCATCGT CATTCTGTAT 
GAAGGGCTTC TGGGCGGGGC CGCTTACGTG AATACCTTCC ACAACATTGC CCTGGAGACC 
AGTGACAAGC ACCGAGAGTT TGCCATGGAA GCTGCCTGCA TTTCTGACAC CTTGGGAATC 
TCCCTGTCAG GGGTCCTGGC CTTGCCTCTG CATGACTTCC TCTGCCACCT CCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008758094.1
CDS	502..1818
Translation	MGSSESSWRRLEDSEREETDSEPQTPPLDNLSVLWKNAVGFWILGLCNNFSYVVMLSAAHDILKQEQASGNQSHVEPGPTPMPHNSSSRFDCNSISTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGVCSAGSFVLVAFSQSVGLSLCGVVLASISSGLGEVTFLSLTAFYPSAVISWWSSGTGGAGLLGSLSYLGLTQAGLSPQHTLLSMLGIPVLMLASYFLLLTSPEPLDPGGQDEAETAARQPLIGTETPESRPGTSWDLSLQERWTVFKGLLRYIIPLVLVYFAEYFINQGLFELLFFRNTSLSHAQQYRWYQMLYQAGVFASRSSLQCCRIRFTWILALLQCLNLAFLLADVCLTFLPSIYLIFIVILYEGLLGGAAYVNTFHNIALETSDKHREFAMEAACISDTLGISLSGVLALPLHDFLCHLP

Target ORF information:

RefSeq Version	XM_008759872.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ceroid-lipofuscinosis, neuronal 3 (Cln3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759872.2

ORF Insert Sequence:

ATGGGAAGCT CTGAGAGCTC GTGGAGGCGC CTTGAGGATT CTGAGAGGGA GGAGACCGAC 
TCAGAGCCCC AAACCCCTCC GTTGGATAAT CTAAGTGTCC TTTGGAAGAA TGCGGTGGGC 
TTCTGGATCT TGGGGCTTTG CAACAACTTC TCATATGTGG TGATGCTGAG CGCTGCCCAT 
GACATCCTTA AGCAGGAGCA GGCATCTGGA AACCAGAGCC ATGTGGAACC AGGCCCAACA 
CCCATGCCCC ATAACAGCTC ATCTCGATTT GATTGCAATT CAATCTCCAC AGCTGCGGTG 
CTCCTAGCAG ACATCCTTCC CACCCTTGTC ATCAAACTCC TGGCTCCTCT TGGCCTTCAT 
TTGCTGCCTT ACAGCCCCCG GGTGCTTGTC AGTGGAGTCT GTTCTGCTGG AAGCTTTGTT 
CTGGTTGCCT TTTCTCAATC AGTGGGGTTA AGCCTGTGTG GAGTGGTTTT GGCCAGCATC 
TCATCAGGTC TAGGGGAGGT CACCTTCCTT TCACTGACTG CCTTCTACCC CAGTGCTGTG 
ATCTCATGGT GGTCTTCAGG AACTGGGGGT GCAGGGCTTC TTGGATCGCT GTCATACCTG 
GGGCTCACCC AGGCTGGCCT CTCCCCGCAG CACACCCTAC TTTCTATGCT GGGGATCCCT 
GTTCTGATGC TAGCCAGCTA TTTCTTGCTG CTCACATCTC CTGAACCCCT GGACCCTGGA 
GGGCAAGACG AGGCAGAGAC TGCTGCCCGG CAGCCTCTCA TAGGCACCGA GACCCCAGAG 
TCTAGGCCAG GTACCAGCTG GGACCTCTCT CTCCAGGAAA GGTGGACAGT GTTCAAGGGC 
CTCTTGCGAT ACATCATCCC TCTGGTGCTG GTCTACTTTG CAGAATACTT TATCAACCAG 
GGGCTTTTTG AGCTCCTGTT TTTCCGGAAC ACATCCTTAA GTCATGCTCA GCAGTACCGA 
TGGTACCAGA TGCTATACCA GGCTGGTGTG TTCGCTTCCC GCTCTTCTCT CCAGTGTTGC 
CGAATCCGGT TCACCTGGAT CCTAGCCCTG CTCCAGTGCC TCAACCTGGC CTTCCTGCTG 
GCAGATGTAT GCTTGACCTT CCTGCCCAGC ATCTACCTCA TCTTCATCGT CATTCTGTAT 
GAAGGGCTTC TGGGCGGGGC CGCTTACGTG AATACCTTCC ACAACATTGC CCTGGAGACC 
AGTGACAAGC ACCGAGAGTT TGCCATGGAA GCTGCCTGCA TTTCTGACAC CTTGGGAATC 
TCCCTGTCAG GGGTCCTGGC CTTGCCTCTG CATGACTTCC TCTGCCACCT CCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cln3 ( XM_008759875.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008758097.1 Rattus norvegicus ceroid-lipofuscinosis, neuronal 3 (Cln3), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa45118
Clone ID Related Accession (Same CDS sequence)	XM_008759875.2
Accession Version	XM_008759875.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1074bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	battenin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008759875.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCCATA ACAGCTCATC TCGATTTGAT TGCAATTCAA TCTCCACAGC TGCGGTGCTC 
CTAGCAGACA TCCTTCCCAC CCTTGTCATC AAACTCCTGG CTCCTCTTGG CCTTCATTTG 
CTGCCTTACA GCCCCCGGGT GCTTGTCAGT GGAGTCTGTT CTGCTGGAAG CTTTGTTCTG 
GTTGCCTTTT CTCAATCAGT GGGGTTAAGC CTGTGTGGAG TGGTTTTGGC CAGCATCTCA 
TCAGGTCTAG GGGAGGTCAC CTTCCTTTCA CTGACTGCCT TCTACCCCAG TGCTGTGATC 
TCATGGTGGT CTTCAGGAAC TGGGGGTGCA GGGCTTCTTG GATCGCTGTC ATACCTGGGG 
CTCACCCAGG CTGGCCTCTC CCCGCAGCAC ACCCTACTTT CTATGCTGGG GATCCCTGTT 
CTGATGCTAG CCAGCTATTT CTTGCTGCTC ACATCTCCTG AACCCCTGGA CCCTGGAGGG 
CAAGACGAGG CAGAGACTGC TGCCCGGCAG CCTCTCATAG GCACCGAGAC CCCAGAGTCT 
AGGCCAGGTA CCAGCTGGGA CCTCTCTCTC CAGGAAAGGT GGACAGTGTT CAAGGGCCTC 
TTGCGATACA TCATCCCTCT GGTGCTGGTC TACTTTGCAG AATACTTTAT CAACCAGGGG 
CTTTTTGAGC TCCTGTTTTT CCGGAACACA TCCTTAAGTC ATGCTCAGCA GTACCGATGG 
TACCAGATGC TATACCAGGC TGGTGTGTTC GCTTCCCGCT CTTCTCTCCA GTGTTGCCGA 
ATCCGGTTCA CCTGGATCCT AGCCCTGCTC CAGTGCCTCA ACCTGGCCTT CCTGCTGGCA 
GATGTATGCT TGACCTTCCT GCCCAGCATC TACCTCATCT TCATCGTCAT TCTGTATGAA 
GGGCTTCTGG GCGGGGCCGC TTACGTGAAT ACCTTCCACA ACATTGCCCT GGAGACCAGT 
GACAAGCACC GAGAGTTTGC CATGGAAGCT GCCTGCATTT CTGACACCTT GGGAATCTCC 
CTGTCAGGGG TCCTGGCCTT GCCTCTGCAT GACTTCCTCT GCCACCTCCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008758097.1
CDS	1149..2222
Translation	MPHNSSSRFDCNSISTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGVCSAGSFVLVAFSQSVGLSLCGVVLASISSGLGEVTFLSLTAFYPSAVISWWSSGTGGAGLLGSLSYLGLTQAGLSPQHTLLSMLGIPVLMLASYFLLLTSPEPLDPGGQDEAETAARQPLIGTETPESRPGTSWDLSLQERWTVFKGLLRYIIPLVLVYFAEYFINQGLFELLFFRNTSLSHAQQYRWYQMLYQAGVFASRSSLQCCRIRFTWILALLQCLNLAFLLADVCLTFLPSIYLIFIVILYEGLLGGAAYVNTFHNIALETSDKHREFAMEAACISDTLGISLSGVLALPLHDFLCHLP

Target ORF information:

RefSeq Version	XM_008759875.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ceroid-lipofuscinosis, neuronal 3 (Cln3), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759875.2

ORF Insert Sequence:

ATGCCCCATA ACAGCTCATC TCGATTTGAT TGCAATTCAA TCTCCACAGC TGCGGTGCTC 
CTAGCAGACA TCCTTCCCAC CCTTGTCATC AAACTCCTGG CTCCTCTTGG CCTTCATTTG 
CTGCCTTACA GCCCCCGGGT GCTTGTCAGT GGAGTCTGTT CTGCTGGAAG CTTTGTTCTG 
GTTGCCTTTT CTCAATCAGT GGGGTTAAGC CTGTGTGGAG TGGTTTTGGC CAGCATCTCA 
TCAGGTCTAG GGGAGGTCAC CTTCCTTTCA CTGACTGCCT TCTACCCCAG TGCTGTGATC 
TCATGGTGGT CTTCAGGAAC TGGGGGTGCA GGGCTTCTTG GATCGCTGTC ATACCTGGGG 
CTCACCCAGG CTGGCCTCTC CCCGCAGCAC ACCCTACTTT CTATGCTGGG GATCCCTGTT 
CTGATGCTAG CCAGCTATTT CTTGCTGCTC ACATCTCCTG AACCCCTGGA CCCTGGAGGG 
CAAGACGAGG CAGAGACTGC TGCCCGGCAG CCTCTCATAG GCACCGAGAC CCCAGAGTCT 
AGGCCAGGTA CCAGCTGGGA CCTCTCTCTC CAGGAAAGGT GGACAGTGTT CAAGGGCCTC 
TTGCGATACA TCATCCCTCT GGTGCTGGTC TACTTTGCAG AATACTTTAT CAACCAGGGG 
CTTTTTGAGC TCCTGTTTTT CCGGAACACA TCCTTAAGTC ATGCTCAGCA GTACCGATGG 
TACCAGATGC TATACCAGGC TGGTGTGTTC GCTTCCCGCT CTTCTCTCCA GTGTTGCCGA 
ATCCGGTTCA CCTGGATCCT AGCCCTGCTC CAGTGCCTCA ACCTGGCCTT CCTGCTGGCA 
GATGTATGCT TGACCTTCCT GCCCAGCATC TACCTCATCT TCATCGTCAT TCTGTATGAA 
GGGCTTCTGG GCGGGGCCGC TTACGTGAAT ACCTTCCACA ACATTGCCCT GGAGACCAGT 
GACAAGCACC GAGAGTTTGC CATGGAAGCT GCCTGCATTT CTGACACCTT GGGAATCTCC 
CTGTCAGGGG TCCTGGCCTT GCCTCTGCAT GACTTCCTCT GCCACCTCCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CLN3 deficient cells display defects in the ARF1-Cdc42 pathway and actin-dependent events.
PloS one9(5)e96647(2014)
Schultz ML,Tecedor L,Stein CS,Stamnes MA,Davidson BL

Amlodipine prevents apoptotic cell death by correction of elevated intracellular calcium in a primary neuronal model of Batten disease (CLN3 disease).
Biochemical and biophysical research communications436(4)645-9(2013 Jul)
Warnock A,Tan L,Li C,An Haack K,Narayan SB,Bennett MJ

Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments.
Cellular and molecular life sciences : CMLS69(12)2075-89(2012 Jun)
Uusi-Rauva K,Kytt?l? A,van der Kant R,Vesa J,Tanhuanp?? K,Neefjes J,Olkkonen VM,Jalanko A

Novel interactions of CLN5 support molecular networking between Neuronal Ceroid Lipofuscinosis proteins.
BMC cell biology1083(2009 Nov)
Lyly A,von Schantz C,Heine C,Schmiedt ML,Sipil? T,Jalanko A,Kytt?l? A

Integral and associated lysosomal membrane proteins.
Traffic (Copenhagen, Denmark)8(12)1676-86(2007 Dec)
Schr?der B,Wrocklage C,Pan C,J?ger R,K?sters B,Sch?fer H,Els?sser HP,Mann M,Hasilik A

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Cln3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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