Rps6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rps6
Entrez Gene ID	29304
Full Name	ribosomal protein S6
General protein information	Preferred Names ribosomal protein S6 Names 40S ribosomal protein S6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q32
Summary	ribosomal protein with many phosphorylated seryl residues [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_017160.1	NP_058856.1	40S ribosomal protein S6

Pathways from BioSystems

Homologies

Homo sapiens (human)	RPS6	NP_001001.2
Rattus norvegicus (Norway rat)	Rps6	NP_058856.1
Kluyveromyces lactis	KLLA0E24047g	XP_455035.1
Eremothecium gossypii	AGOS_AGR197C	NP_986863.1
Magnaporthe oryzae (rice blast fungus)	MGG_03236	XP_003716740.1
Neurospora crassa	NCU08502	XP_963431.1
	RPS6	XP_001109421.1
Rattus norvegicus (Norway rat)	LOC100911372	XP_003750019.1
Danio rerio (zebrafish)	rps6	NP_001003728.1
Drosophila melanogaster (fruit fly)	RpS6	NP_511073.1
Schizosaccharomyces pombe (fission yeast)	rps601	NP_592833.1
Gallus gallus (chicken)	RPS6	NP_990556.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002919	XP_001237411.2
Saccharomyces cerevisiae (baker's yeast)	RPS6B	NP_009740.3
Saccharomyces cerevisiae (baker's yeast)	RPS6A	NP_015235.1
Schizosaccharomyces pombe (fission yeast)	rps602	NP_594138.1
Arabidopsis thaliana (thale cress)	EMB3010	NP_196598.1
Oryza sativa (rice)	Os03g0390000	NP_001050273.1
Oryza sativa (rice)	Os07g0622100	NP_001060313.1
Xenopus tropicalis (tropical clawed frog)	rps6	NP_989152.1
Pan troglodytes (chimpanzee)	RPS6	XP_003951447.1
Bos taurus (cattle)	RPS6	NP_001015548.1
Mus musculus (house mouse)	Rps6	NP_033122.1
Arabidopsis thaliana (thale cress)	RPS6	NP_194898.1
	LOC718556	XP_001111414.2
Canis lupus familiaris (dog)	RPS6	NP_001239099.1
Caenorhabditis elegans (roundworm)	rps-6	NP_493435.1

Gene Ontology
Bibliography

Related articles in PubMed

Synaptic activation of ribosomal protein S6 phosphorylation occurs locally in activated dendritic domains.
Pirbhoy PS, Farris S, Steward O
Learning & memory (Cold Spring Harbor, N.Y.)23(6)255-69(2016 06)

Roles of Sestrin2 and Ribosomal Protein S6 in Transient Global Ischemia-Induced Hippocampal Neuronal Injury.
Chuang YC, Yang JL, Yang DI, Lin TK, Liou CW, Chen SD
International journal of molecular sciences16(11)26406-16(2015 Nov)

rpS6 regulates blood-testis barrier dynamics through Akt-mediated effects on MMP-9.
Mok KW, Mruk DD, Cheng CY
Journal of cell science127(Pt 22)4870-82(2014 Nov)

Insulin-like growth factor I induces proliferation and migration of porcine trophectoderm cells through multiple cell signaling pathways, including protooncogenic protein kinase 1 and mitogen-activated protein kinase.
Jeong W, Song G, Bazer FW, Kim J
Molecular and cellular endocrinology384(1-2)175-84(2014 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Synaptic activation of ribosomal protein S6 phosphorylation occurs locally in activated dendritic domains. results constrain hypotheses about the possible role of rpS6 phosphorylation in regulating postsynaptic protein synthesis during induction of synaptic plasticity.
Title: Synaptic activation of ribosomal protein S6 phosphorylation occurs locally in activated dendritic domains.

TGI-induced sestrin2 expression contributed to RpS6 phosphorylation and neuroprotection against ischemic injury in the hippocampal CA1 subfield.
Title: Roles of Sestrin2 and Ribosomal Protein S6 in Transient Global Ischemia-Induced Hippocampal Neuronal Injury.

rpS6 in the mTORC1 pathway regulates blood-testis barrier restructuring via its effects on the F-actin organization and protein recruitment at the blood-testis barrier
Title: rpS6 Regulates blood-testis barrier dynamics by affecting F-actin organization and protein recruitment.

A strong and sustained phosphorylation of ribosomal protein S6 on its serine 240 and 244 residues (p-Ser(2)(2)-S6rp), which was found to be principally expressed in striatal cholinergic interneurons in basal conditions.
Title: Striatal cholinergic interneurons display activity-related phosphorylation of ribosomal protein S6.

Load-dependent maintenance or upregulation of the nucleolar number and/or phosphorylation of S6 and HSP27 plays the important role(s) in the regulation of skeletal muscle mass.
Title: Role(s) of nucleoli and phosphorylation of ribosomal protein S6 and/or HSP27 in the regulation of muscle mass.

The following Rps6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rps6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42335	NM_017160.1 Latest version!	Rattus norvegicus ribosomal protein S6 (Rps6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rps6 ( NM_017160.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_058856.1 Rattus norvegicus ribosomal protein S6 (Rps6), mRNA.

Price & Availability↑

CloneID	ORa42335
Clone ID Related Accession (Same CDS sequence)	NM_017160.1
Accession Version	NM_017160.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 750bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	40S ribosomal protein S6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M29358.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M29358.1 [ECO:0000332] ##Evidence-Data-END##

ATGAAGCTGA ATATCTCCTT CCCTGCCACT GGCTGTCAGA AACTCATAGA AGTGGATGAC 
GAACGCAAGC TTCGTACGTT CTATGAGAAG CGCATGGCCA CAGAAGTAGC TGCTGATGCT 
CTTGGTGAAG AGTGGAAGGG TTATGTGGTC CGGATCAGCG GTGGGAATGA CAAACAAGGT 
TTTCCCATGA AGCAAGGCGT TTTGACCCAT GGCAGAGTGC GCCTGCTTTT GAGTAAGGGG 
CATTCTTGTT ATAGACCTAG GAGAACTGGA GAGAGGAAGC GCAAGTCTGT CCGAGGATGC 
ATTGTGGATG CCAACCTGAG TGTTCTCAAC TTGGTTATTG TAAAAAAAGG AGAGAAGGAT 
ATTCCAGGAC TGACAGATAC CACTGTGCCT CGTCGGTTGG GACCTAAAAG AGCTAGTAGA 
ATCCGAAAGC TTTTTAATCT CTCCAAAGAA GATGATGTCC GCCAGTATGT TGTTAGAAAG 
CCCTTAAACA AAGAAGGTAA GAAGCCCAGG ACCAAAGCGC CCAAGATTCA GCGTCTTGTT 
ACTCCCCGTG TCCTGCAACA CAAACGCCGA CGTATTGCTC TGAAGAAGCA ACGCACTAAG 
AAAAACAAGG AGGAGGCTGC AGAATATGCT AAACTTTTGG CCAAGAGAAT GAAGGAAGCC 
AAAGAGAAGC GCCAGGAACA GATTGCCAAG AGACGTAGGC TGTCTTCGCT GAGAGCTTCT 
ACTTCTAAAT CTGAGTCCAG TCAAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058856.1
CDS	16..765
Translation	MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADALGEEWKGYVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPRRLGPKRASRIRKLFNLSKEDDVRQYVVRKPLNKEGKKPRTKAPKIQRLVTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK

Target ORF information:

RefSeq Version	NM_017160.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ribosomal protein S6 (Rps6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017160.1

ORF Insert Sequence:

ATGAAGCTGA ATATCTCCTT CCCTGCCACT GGCTGTCAGA AACTCATAGA AGTGGATGAC 
GAACGCAAGC TTCGTACGTT CTATGAGAAG CGCATGGCCA CAGAAGTAGC TGCTGATGCT 
CTTGGTGAAG AGTGGAAGGG TTATGTGGTC CGGATCAGCG GTGGGAATGA CAAACAAGGT 
TTTCCCATGA AGCAAGGCGT TTTGACCCAT GGCAGAGTGC GCCTGCTTTT GAGTAAGGGG 
CATTCTTGTT ATAGACCTAG GAGAACTGGA GAGAGGAAGC GCAAGTCTGT CCGAGGATGC 
ATTGTGGATG CCAACCTGAG TGTTCTCAAC TTGGTTATTG TAAAAAAAGG AGAGAAGGAT 
ATTCCAGGAC TGACAGATAC CACTGTGCCT CGTCGGTTGG GACCTAAAAG AGCTAGTAGA 
ATCCGAAAGC TTTTTAATCT CTCCAAAGAA GATGATGTCC GCCAGTATGT TGTTAGAAAG 
CCCTTAAACA AAGAAGGTAA GAAGCCCAGG ACCAAAGCGC CCAAGATTCA GCGTCTTGTT 
ACTCCCCGTG TCCTGCAACA CAAACGCCGA CGTATTGCTC TGAAGAAGCA ACGCACTAAG 
AAAAACAAGG AGGAGGCTGC AGAATATGCT AAACTTTTGG CCAAGAGAAT GAAGGAAGCC 
AAAGAGAAGC GCCAGGAACA GATTGCCAAG AGACGTAGGC TGTCTTCGCT GAGAGCTTCT 
ACTTCTAAAT CTGAGTCCAG TCAAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Synaptic activation of ribosomal protein S6 phosphorylation occurs locally in activated dendritic domains.
Learning & memory (Cold Spring Harbor, N.Y.)23(6)255-69(2016 06)
Pirbhoy PS,Farris S,Steward O

Roles of Sestrin2 and Ribosomal Protein S6 in Transient Global Ischemia-Induced Hippocampal Neuronal Injury.
International journal of molecular sciences16(11)26406-16(2015 Nov)
Chuang YC,Yang JL,Yang DI,Lin TK,Liou CW,Chen SD

rpS6 regulates blood-testis barrier dynamics through Akt-mediated effects on MMP-9.
Journal of cell science127(Pt 22)4870-82(2014 Nov)
Mok KW,Mruk DD,Cheng CY

Insulin-like growth factor I induces proliferation and migration of porcine trophectoderm cells through multiple cell signaling pathways, including protooncogenic protein kinase 1 and mitogen-activated protein kinase.
Molecular and cellular endocrinology384(1-2)175-84(2014 Mar)
Jeong W,Song G,Bazer FW,Kim J

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Rps6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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