Pak4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pak4
Entrez Gene ID	292756
Full Name	p21 (RAC1) activated kinase 4
General protein information	Preferred Names p21 (RAC1) activated kinase 4 Names serine/threonine-protein kinase PAK 4 p21 (CDKN1A)-activated kinase 4 p21 protein (Cdc42/Rac)-activated kinase 4 p21-activated kinase 4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q21

mRNA and Protein(s)

mRNA	Protein	Name
NM_001106238.1	NP_001099708.1	serine/threonine-protein kinase PAK 4
XM_008759119.2	XP_008757341.1	serine/threonine-protein kinase PAK 4 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	PAK4	XP_005616659.1
Gallus gallus (chicken)	PAK4	XP_001233796.3
Homo sapiens (human)	PAK4	NP_001014831.1
Xenopus tropicalis (tropical clawed frog)	pak4	NP_001090671.1
	PAK4	XP_001085295.1
Mus musculus (house mouse)	Pak4	NP_081746.1
Rattus norvegicus (Norway rat)	Pak4	NP_001099708.1
Bos taurus (cattle)	PAK4	NP_001069652.1
Danio rerio (zebrafish)	pak4	NP_001002222.1
Drosophila melanogaster (fruit fly)	mbt	NP_523375.2

Gene Ontology
Bibliography

Related articles in PubMed

Nigral dopaminergic PAK4 prevents neurodegeneration in rat models of Parkinson's disease.
Won SY, Park MH, You ST, Choi SW, Kim HK, McLean C, Bae SC, Kim SR, Jin BK, Lee KH, Shin EY, Kim EG
Science translational medicine8(367)367ra170(2016 Nov)

An in cellulo-derived structure of PAK4 in complex with its inhibitor Inka1.
Baskaran Y, Ang KC, Anekal PV, Chan WL, Grimes JM, Manser E, Robinson RC
Nature communications68681(2015 Nov)

p21-Activated kinase 4 predicts early recurrence and poor survival in patients with nonmetastatic clear cell renal cell carcinoma.
Liu W, Yang Y, Liu Y, Liu H, Zhang W, Xu L, Zhu Y, Xu J
Urologic oncology33(5)205.e13-21(2015 May)

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PAK4 activity was markedly decreased in postmortem brain tissue from Parkinson's disease (PD) patients and in rodent models of PD. Expression of constitutively active PAK4(S445N/S474E) (caPAK4) protected DA neurons in both the 6-hydroxydopamine and alpha-synuclein rat models of PD and preserved motor function.
Title: Nigral dopaminergic PAK4 prevents neurodegeneration in rat models of Parkinson's disease.

The following Pak4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pak4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00513	NM_001106238.1 Latest version!	Rattus norvegicus p21 (RAC1) activated kinase 4 (Pak4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$349.30 $499.00
ORa45060	XM_008759119.2 Latest version!	Rattus norvegicus p21 (RAC1) activated kinase 4 (Pak4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pak4 ( NM_001106238.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099708.1 Rattus norvegicus p21 (RAC1) activated kinase 4 (Pak4), mRNA.

Price & Availability↑

CloneID	ORa00513
Clone ID Related Accession (Same CDS sequence)	NM_001106238.1
Accession Version	NM_001106238.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1782bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-08-18
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein kinase PAK 4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473979.2. On or before Oct 4, 2007 this sequence version replaced XM_218388.3, XM_001073872.1, XM_001073813.1, XM_001073846.1. ##Evidence-Data-START## Transcript exon combination :: BC168940.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTTTGGAA AGAAGAAGAA GCGGGTGGAG ATCTCGGCCC CATCCAACTT CGAGCACCGC 
GTACACACAG GCTTCGATCA GCATGAGCAG AAGTTCACAG GGCTGCCCCG CCAGTGGCAG 
AGCCTGATTG AGGAGTCAGC GCGCAGACCC AAGCCCCTGA TCGACCCTGC TTGCATCACT 
TCCATCCAGC CTGGAGCCCC CAAGACCATC GTGCGGGGCA GCAAAGGTGC CAAGGATGGG 
GCTCTCACAC TGCTGCTTGA CGAATTTGAG AACATGTCGG TGACACGCTC CAACTCCCTG 
CGCAGAGAGA GTCCTCCACC CCCTGCCCGC GCCCATCAGG AAAATGGAAT GCTGGAGGAG 
CGGGCAGCTC TGGCCAGAAT GGCCCCTGAC AAAGCTGGAG GCAGGGGCCG GGCCACAGGC 
CACAGTGAGG CAGGCAGTGG CAGTGGTGAC AGACGGCGGG TGGGGCCAGA GAAGAGGCCC 
AAGTCATCAA GGGAGGGCCC AGGAGGGCCC CAGGAGGTCT CCCGTGATAA GCGCCCCCTC 
TCTGGTCCTG ATGTCAGCAC TCCTCAGCCT GGCAGTCTGG CCAGCGAGAC AAAACTAGCA 
GCTGGCAGAC CCTTTAACAC ATACCCTCGG GCTGACACGG ACCACCCACC CCGGGGTACC 
CAGGGGGAGC CACACACCAT GGCCCCTAAT GGGCCATCAG CCATAGGCCT GGCTGCTCCT 
CAGTCTTCCT CCTCCTCCCG GCCTCCCACC CGAGCCCGTG GTGCTCCCAG CCCGGGAGTG 
CTGGGTCCCC ATGCCTCTGA GCCCCAGTTG GCCCCCCCAG CACGTGCCCT TGCTGCCCCT 
GCTGTACCCC CTGCTCCTGG GCCCCCTGGG CCTCGGTCAC CACAGCGGGA GCCCCAACGA 
GTATCCCATG AGCAGTTCCG GGCCGCCCTG CAGCTAGTGG TGGACCCAGG GGACCCTCGT 
TCCTATCTAG ACAACTTCAT CAAGATTGGC GAGGGCTCTA CAGGTATTGT GTGCATAGCC 
ACTGTGCGAA GCTCGGGCAA ACTGGTGGCC GTCAAGAAGA TGGACTTGCG TAAGCAGCAG 
AGACGTGAGC TGCTCTTCAA TGAGGTGGTG ATCATGAGGG ACTACCGGCA TGAAAACGTG 
GTGGAGATGT ACAACAGCTA CCTGGTAGGC GATGAGCTCT GGGTGGTCAT GGAGTTCCTG 
GAGGGAGGCG CCCTCACGGA TATTGTCACC CACACCAGGA TGAATGAGGA ACAGATTGCC 
GCCGTGTGCC TGGCTGTGCT TCAGGCGCTG TCTGTGCTCC ATGCCCAGGG CGTCATCCAC 
CGTGACATCA AGAGTGACTC CATCCTGCTG ACCCACGATG GCCGGGTGAA GCTGTCCGAC 
TTCGGGTTTT GTGCCCAGGT GAGCAAGGAG GTGCCTCGGA GGAAGTCGCT GGTGGGCACC 
CCATACTGGA TGGCCCCAGA GCTCATCTCC CGCCTTCCCT ACGGGCCAGA GGTGGATATC 
TGGTCACTGG GGGTAATGGT GATCGAGATG GTGGATGGGG AACCCCCCTA CTTCAACGAG 
CCACCCCTGA AAGCCATGAA GATGATTCGG GACAACCTGC CGCCCCGACT GAAGAACCTG 
CACAAGGCCT CACCATCTCT GAAAGGCTTC TTGGATCGCC TGCTGGTGCG TGACCCAGCC 
CAGCGGGCCA CTGCTGCTGA GCTGCTGAAG CACCCGTTCC TCACCAAGGC GGGGCCGCCA 
GCCAGCATTG TGCCCCTTAT GCGCCAGCAC CGAAACAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099708.1
CDS	244..2025
Translation	MFGKKKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLIDPACITSIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRESPPPPARAHQENGMLEERAALARMAPDKAGGRGRATGHSEAGSGSGDRRRVGPEKRPKSSREGPGGPQEVSRDKRPLSGPDVSTPQPGSLASETKLAAGRPFNTYPRADTDHPPRGTQGEPHTMAPNGPSAIGLAAPQSSSSSRPPTRARGAPSPGVLGPHASEPQLAPPARALAAPAVPPAPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYRHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGVMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKASPSLKGFLDRLLVRDPAQRATAAELLKHPFLTKAGPPASIVPLMRQHRNR

Target ORF information:

RefSeq Version	NM_001106238.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus p21 (RAC1) activated kinase 4 (Pak4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106238.1

ORF Insert Sequence:

ATGTTTGGAA AGAAGAAGAA GCGGGTGGAG ATCTCGGCCC CATCCAACTT CGAGCACCGC 
GTACACACAG GCTTCGATCA GCATGAGCAG AAGTTCACAG GGCTGCCCCG CCAGTGGCAG 
AGCCTGATTG AGGAGTCAGC GCGCAGACCC AAGCCCCTGA TCGACCCTGC TTGCATCACT 
TCCATCCAGC CTGGAGCCCC CAAGACCATC GTGCGGGGCA GCAAAGGTGC CAAGGATGGG 
GCTCTCACAC TGCTGCTTGA CGAATTTGAG AACATGTCGG TGACACGCTC CAACTCCCTG 
CGCAGAGAGA GTCCTCCACC CCCTGCCCGC GCCCATCAGG AAAATGGAAT GCTGGAGGAG 
CGGGCAGCTC TGGCCAGAAT GGCCCCTGAC AAAGCTGGAG GCAGGGGCCG GGCCACAGGC 
CACAGTGAGG CAGGCAGTGG CAGTGGTGAC AGACGGCGGG TGGGGCCAGA GAAGAGGCCC 
AAGTCATCAA GGGAGGGCCC AGGAGGGCCC CAGGAGGTCT CCCGTGATAA GCGCCCCCTC 
TCTGGTCCTG ATGTCAGCAC TCCTCAGCCT GGCAGTCTGG CCAGCGAGAC AAAACTAGCA 
GCTGGCAGAC CCTTTAACAC ATACCCTCGG GCTGACACGG ACCACCCACC CCGGGGTACC 
CAGGGGGAGC CACACACCAT GGCCCCTAAT GGGCCATCAG CCATAGGCCT GGCTGCTCCT 
CAGTCTTCCT CCTCCTCCCG GCCTCCCACC CGAGCCCGTG GTGCTCCCAG CCCGGGAGTG 
CTGGGTCCCC ATGCCTCTGA GCCCCAGTTG GCCCCCCCAG CACGTGCCCT TGCTGCCCCT 
GCTGTACCCC CTGCTCCTGG GCCCCCTGGG CCTCGGTCAC CACAGCGGGA GCCCCAACGA 
GTATCCCATG AGCAGTTCCG GGCCGCCCTG CAGCTAGTGG TGGACCCAGG GGACCCTCGT 
TCCTATCTAG ACAACTTCAT CAAGATTGGC GAGGGCTCTA CAGGTATTGT GTGCATAGCC 
ACTGTGCGAA GCTCGGGCAA ACTGGTGGCC GTCAAGAAGA TGGACTTGCG TAAGCAGCAG 
AGACGTGAGC TGCTCTTCAA TGAGGTGGTG ATCATGAGGG ACTACCGGCA TGAAAACGTG 
GTGGAGATGT ACAACAGCTA CCTGGTAGGC GATGAGCTCT GGGTGGTCAT GGAGTTCCTG 
GAGGGAGGCG CCCTCACGGA TATTGTCACC CACACCAGGA TGAATGAGGA ACAGATTGCC 
GCCGTGTGCC TGGCTGTGCT TCAGGCGCTG TCTGTGCTCC ATGCCCAGGG CGTCATCCAC 
CGTGACATCA AGAGTGACTC CATCCTGCTG ACCCACGATG GCCGGGTGAA GCTGTCCGAC 
TTCGGGTTTT GTGCCCAGGT GAGCAAGGAG GTGCCTCGGA GGAAGTCGCT GGTGGGCACC 
CCATACTGGA TGGCCCCAGA GCTCATCTCC CGCCTTCCCT ACGGGCCAGA GGTGGATATC 
TGGTCACTGG GGGTAATGGT GATCGAGATG GTGGATGGGG AACCCCCCTA CTTCAACGAG 
CCACCCCTGA AAGCCATGAA GATGATTCGG GACAACCTGC CGCCCCGACT GAAGAACCTG 
CACAAGGCCT CACCATCTCT GAAAGGCTTC TTGGATCGCC TGCTGGTGCG TGACCCAGCC 
CAGCGGGCCA CTGCTGCTGA GCTGCTGAAG CACCCGTTCC TCACCAAGGC GGGGCCGCCA 
GCCAGCATTG TGCCCCTTAT GCGCCAGCAC CGAAACAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pak4 ( XM_008759119.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008757341.1 Rattus norvegicus p21 (RAC1) activated kinase 4 (Pak4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa45060
Clone ID Related Accession (Same CDS sequence)	XM_008759119.2
Accession Version	XM_008759119.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1782bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein kinase PAK 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008759119.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTTGGAA AGAAGAAGAA GCGGGTGGAG ATCTCGGCCC CATCCAACTT CGAGCACCGC 
GTACACACAG GCTTCGATCA GCATGAGCAG AAGTTCACAG GGCTTCCCCG CCAGTGGCAG 
AGCCTGATTG AGGAGTCAGC GCGCAGACCC AAGCCCCTGA TCGACCCTGC TTGCATCACT 
TCCATCCAGC CTGGAGCCCC CAAGACCATC GTGCGGGGCA GCAAAGGTGC CAAGGATGGG 
GCTCTCACAC TGCTGCTTGA CGAATTTGAG AACATGTCGG TGACACGCTC CAACTCCCTG 
CGCAGAGAGA GTCCTCCACC CCCTGCCCGC GCCCATCAGG AAAATGGAAT GCTGGAGGAG 
CGGGCAGCTC TGGCCAGAAT GGCCCCTGAC AAAGCTGGAG GCAGGGGCCG GGCCACAGGC 
CACAGTGAGG CAGGCAGTGG CAGTGGTGAC AGACGGCGGG TGGGGCCAGA GAAGAGGCCC 
AAGTCATCAA GGGAGGGCCC AGGAGGGCCC CAGGAGGTCT CCCGTGATAA GCGCCCCCTC 
TCTGGTCCTG ATGTCAGCAC TCCTCAGCCT GGCAGTCTGG CCAGCGAGAC AAAACTAGCA 
GCTGGCAGAC CCTTTAACAC ATACCCTCGG GCTGACACGG ACCACCCACC CCGGGGTACC 
CAGGGGGAGC CACACACCAT GGCCCCTAAT GGGCCATCAG CCATAGGCCT GGCTGCTCCT 
CAGTCTTCCT CCTCCTCCCG GCCTCCCACC CGAGCCCGTG GTGCTCCCAG CCCGGGAGTG 
CTGGGTCCCC ATGCCTCTGA GCCCCAGTTG GCCCCCCCAG CACGTGCCCT TGCTGCCCCT 
GCTGTACCCC CTGCTCCTGG GCCCCCTGGG CCTCGGTCAC CACAGCGGGA GCCCCAACGA 
GTATCCCATG AGCAGTTCCG GGCCGCCCTG CAGCTAGTGG TGGACCCAGG GGACCCTCGT 
TCCTATCTAG ACAACTTCAT CAAGATTGGC GAGGGCTCTA CAGGTATTGT GTGCATAGCC 
ACTGTGCGAA GCTCGGGCAA ACTGGTGGCC GTCAAGAAGA TGGACTTGCG TAAGCAGCAG 
AGACGTGAGC TGCTCTTCAA TGAGGTGGTG ATCATGAGGG ACTACCGGCA TGAAAACGTG 
GTGGAGATGT ACAACAGCTA CCTGGTAGGC GATGAGCTCT GGGTGGTCAT GGAGTTCCTG 
GAGGGAGGCG CCCTCACGGA TATTGTCACC CACACCAGGA TGAATGAGGA ACAGATTGCC 
GCCGTGTGCC TGGCTGTGCT TCAGGCGCTG TCTGTGCTCC ATGCCCAGGG CGTCATCCAC 
CGTGACATCA AGAGTGACTC CATCCTGCTG ACCCACGATG GCCGGGTGAA GCTGTCCGAC 
TTCGGGTTTT GTGCCCAGGT GAGCAAGGAG GTGCCTCGGA GGAAGTCGCT GGTGGGCACC 
CCATACTGGA TGGCCCCAGA GCTCATCTCC CGCCTTCCCT ACGGGCCAGA GGTGGATATC 
TGGTCACTGG GGGTAATGGT GATCGAGATG GTGGATGGGG AACCCCCCTA CTTCAACGAG 
CCACCCCTGA AAGCCATGAA GATGATTCGG GACAACCTGC CGCCCCGACT GAAGAACCTG 
CACAAGGCCT CACCATCTCT GAAAGGCTTC TTGGATCGCC TGCTGGTGCG TGACCCAGCC 
CAGCGGGCCA CTGCTGCTGA GCTGCTGAAG CACCCGTTCC TCACCAAGGC GGGGCCGCCA 
GCCAGCATTG TGCCCCTTAT GCGCCAGCAC CGAAACAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008757341.1
CDS	2341..4122
Translation	MFGKKKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLIDPACITSIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRESPPPPARAHQENGMLEERAALARMAPDKAGGRGRATGHSEAGSGSGDRRRVGPEKRPKSSREGPGGPQEVSRDKRPLSGPDVSTPQPGSLASETKLAAGRPFNTYPRADTDHPPRGTQGEPHTMAPNGPSAIGLAAPQSSSSSRPPTRARGAPSPGVLGPHASEPQLAPPARALAAPAVPPAPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYRHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGVMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKASPSLKGFLDRLLVRDPAQRATAAELLKHPFLTKAGPPASIVPLMRQHRNR

Target ORF information:

RefSeq Version	XM_008759119.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus p21 (RAC1) activated kinase 4 (Pak4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759119.2

ORF Insert Sequence:

ATGTTTGGAA AGAAGAAGAA GCGGGTGGAG ATCTCGGCCC CATCCAACTT CGAGCACCGC 
GTACACACAG GCTTCGATCA GCATGAGCAG AAGTTCACAG GGCTTCCCCG CCAGTGGCAG 
AGCCTGATTG AGGAGTCAGC GCGCAGACCC AAGCCCCTGA TCGACCCTGC TTGCATCACT 
TCCATCCAGC CTGGAGCCCC CAAGACCATC GTGCGGGGCA GCAAAGGTGC CAAGGATGGG 
GCTCTCACAC TGCTGCTTGA CGAATTTGAG AACATGTCGG TGACACGCTC CAACTCCCTG 
CGCAGAGAGA GTCCTCCACC CCCTGCCCGC GCCCATCAGG AAAATGGAAT GCTGGAGGAG 
CGGGCAGCTC TGGCCAGAAT GGCCCCTGAC AAAGCTGGAG GCAGGGGCCG GGCCACAGGC 
CACAGTGAGG CAGGCAGTGG CAGTGGTGAC AGACGGCGGG TGGGGCCAGA GAAGAGGCCC 
AAGTCATCAA GGGAGGGCCC AGGAGGGCCC CAGGAGGTCT CCCGTGATAA GCGCCCCCTC 
TCTGGTCCTG ATGTCAGCAC TCCTCAGCCT GGCAGTCTGG CCAGCGAGAC AAAACTAGCA 
GCTGGCAGAC CCTTTAACAC ATACCCTCGG GCTGACACGG ACCACCCACC CCGGGGTACC 
CAGGGGGAGC CACACACCAT GGCCCCTAAT GGGCCATCAG CCATAGGCCT GGCTGCTCCT 
CAGTCTTCCT CCTCCTCCCG GCCTCCCACC CGAGCCCGTG GTGCTCCCAG CCCGGGAGTG 
CTGGGTCCCC ATGCCTCTGA GCCCCAGTTG GCCCCCCCAG CACGTGCCCT TGCTGCCCCT 
GCTGTACCCC CTGCTCCTGG GCCCCCTGGG CCTCGGTCAC CACAGCGGGA GCCCCAACGA 
GTATCCCATG AGCAGTTCCG GGCCGCCCTG CAGCTAGTGG TGGACCCAGG GGACCCTCGT 
TCCTATCTAG ACAACTTCAT CAAGATTGGC GAGGGCTCTA CAGGTATTGT GTGCATAGCC 
ACTGTGCGAA GCTCGGGCAA ACTGGTGGCC GTCAAGAAGA TGGACTTGCG TAAGCAGCAG 
AGACGTGAGC TGCTCTTCAA TGAGGTGGTG ATCATGAGGG ACTACCGGCA TGAAAACGTG 
GTGGAGATGT ACAACAGCTA CCTGGTAGGC GATGAGCTCT GGGTGGTCAT GGAGTTCCTG 
GAGGGAGGCG CCCTCACGGA TATTGTCACC CACACCAGGA TGAATGAGGA ACAGATTGCC 
GCCGTGTGCC TGGCTGTGCT TCAGGCGCTG TCTGTGCTCC ATGCCCAGGG CGTCATCCAC 
CGTGACATCA AGAGTGACTC CATCCTGCTG ACCCACGATG GCCGGGTGAA GCTGTCCGAC 
TTCGGGTTTT GTGCCCAGGT GAGCAAGGAG GTGCCTCGGA GGAAGTCGCT GGTGGGCACC 
CCATACTGGA TGGCCCCAGA GCTCATCTCC CGCCTTCCCT ACGGGCCAGA GGTGGATATC 
TGGTCACTGG GGGTAATGGT GATCGAGATG GTGGATGGGG AACCCCCCTA CTTCAACGAG 
CCACCCCTGA AAGCCATGAA GATGATTCGG GACAACCTGC CGCCCCGACT GAAGAACCTG 
CACAAGGCCT CACCATCTCT GAAAGGCTTC TTGGATCGCC TGCTGGTGCG TGACCCAGCC 
CAGCGGGCCA CTGCTGCTGA GCTGCTGAAG CACCCGTTCC TCACCAAGGC GGGGCCGCCA 
GCCAGCATTG TGCCCCTTAT GCGCCAGCAC CGAAACAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Nigral dopaminergic PAK4 prevents neurodegeneration in rat models of Parkinson's disease.
Science translational medicine8(367)367ra170(2016 Nov)
Won SY,Park MH,You ST,Choi SW,Kim HK,McLean C,Bae SC,Kim SR,Jin BK,Lee KH,Shin EY,Kim EG

An in cellulo-derived structure of PAK4 in complex with its inhibitor Inka1.
Nature communications68681(2015 Nov)
Baskaran Y,Ang KC,Anekal PV,Chan WL,Grimes JM,Manser E,Robinson RC

p21-Activated kinase 4 predicts early recurrence and poor survival in patients with nonmetastatic clear cell renal cell carcinoma.
Urologic oncology33(5)205.e13-21(2015 May)
Liu W,Yang Y,Liu Y,Liu H,Zhang W,Xu L,Zhu Y,Xu J

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Science signaling7(354)rs7(2014 Dec)
Guo Z,Neilson LJ,Zhong H,Murray PS,Zanivan S,Zaidel-Bar R

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Pak4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報