Acvr2a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Acvr2a
Entrez Gene ID	29263
Full Name	activin A receptor type 2A
Synonyms	Acvr2,rActR-II
General protein information	Preferred Names activin A receptor type 2A Names activin receptor type-2A ACTR-IIA activin A receptor, type IIA activin receptor IIA activin receptor type IIA type II activin receptor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q12
Summary	acts as a receptor for activin A and inhibin A [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031571.2	NP_113759.1	activin receptor type-2A precursor
XM_008761703.2	XP_008759925.1	activin receptor type-2A isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	ACVR2A	NP_001265508.1
	ACVR2A	XP_001095960.2
Pan troglodytes (chimpanzee)	ACVR2A	XP_003949946.1
Canis lupus familiaris (dog)	ACVR2A	XP_005632022.1
Mus musculus (house mouse)	Acvr2a	NP_031422.3
Danio rerio (zebrafish)	acvr2aa	NP_001103748.1
Xenopus tropicalis (tropical clawed frog)	acvr2a	NP_001135613.1
Bos taurus (cattle)	ACVR2A	NP_776652.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000763	XP_311300.4
Rattus norvegicus (Norway rat)	Acvr2a	NP_113759.1
Gallus gallus (chicken)	ACVR2A	NP_990698.1
Drosophila melanogaster (fruit fly)	put	NP_001262574.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolving New Skeletal Traits by cis-Regulatory Changes in Bone Morphogenetic Proteins.
Indjeian VB, Kingman GA, Jones FC, Guenther CA, Grimwood J, Schmutz J, Myers RM, Kingsley DM
Cell164(1-2)45-56(2016 Jan)

Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells.
Upton PD, Davies RJ, Trembath RC, Morrell NW
The Journal of biological chemistry284(23)15794-804(2009 Jun)

BMP-2/4 and BMP-6/7 differentially utilize cell surface receptors to induce osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells.
Lavery K, Swain P, Falb D, Alaoui-Ismaili MH
The Journal of biological chemistry283(30)20948-58(2008 Jul)

Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin.
Xia Y, Babitt JL, Sidis Y, Chung RT, Lin HY
Blood111(10)5195-204(2008 May)

Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development.
Andersson O, Bertolino P, Ib??ez CF
Developmental biology311(2)500-11(2007 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In a rat model of HF, we demonstrated a concerted induction of the gene expression of activin betaA and activin receptors IA, IB, IIA, and IIB after myocardial infarction.
Title: Elevated levels of activin A in heart failure: potential role in myocardial remodeling.

The following Acvr2a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Acvr2a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa43242	XM_008761703.2 Latest version!	Rattus norvegicus activin A receptor type 2A (Acvr2a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa08130	NM_031571.2 Latest version!	Rattus norvegicus activin A receptor type 2A (Acvr2a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Acvr2a ( XM_008761703.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008759925.1 Rattus norvegicus activin A receptor type 2A (Acvr2a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa43242
Clone ID Related Accession (Same CDS sequence)	XM_008761703.2
Accession Version	XM_008761703.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1566bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	activin receptor type-2A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008761703.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAGCTG CTGCAAAGTT GGCGTTCGCC GTCTTTCTTA TCTCTTGCTC TTCAGGTGCT 
ATACTTGGCA GATCGGAAAC TCAGGAGTGT CTTTTCTTTA ATGCTAATTG GGAAAGAGAC 
AGAACCAATC AGACTGGTGT TGAGCCTTGC TATGGTGATA AAGACAAACG ACGACATTGT 
TTTGCTACCT GGAAGAATAT TTCTGGTTCC ATTGAAATAG TAAAGCAAGG TTGTTGGCTG 
GATGATATCA ACTGCTATGA CAGGACTGAT TGTATAGAAA AAAAAGACAG CCCTGAAGTG 
TACTTTTGTT GCTGTGAGGG CAATATGTGT AATGAAAAGT TCTCTTATTT TCCGGAGATG 
GAAGTCACAC AGCCCACATC AAATCCTGTT ACCCCGAAAC CACCCTACTA CAACATCCTG 
CTGTATTCCT TGGTACCACT TATGTTAATT GCGGGGATTG TCATTTGTGC GTTTTGGGTG 
TACAGACATC ACAAGATGGC CTACCCTCCT GTACTTGTTC CTACTCAGCA CGCCTTTCAT 
ATAATGATAG AGGACCCTGG ACCACCTCCA CCTTCCCCAT TACTAGGGTT GAAGCCATTG 
CAGCTATTGG AAGTGAAAGC AAGGGGAAGA TTTGGTTGTG TCTGGAAAGC CCAGTTGCTC 
AATGAGTATG TGGCTGTCAA AATATTTCCG ATACAGGACA AACAGTCCTG GCAGAATGAA 
TATGAAGTCT ATAGTTTACC TGGTATGAAG CATGAAAACA TACTACAGTT CATTGGTGCA 
GAGAAAAGAG GCACCAGTGT TGATGTGGAC CTGTGGCTAA TCACGGCTTT TCATGAAAAG 
GGCTCACTGT CAGACTTTCT TAAGGCTAAT GTGGTCTCTT GGAATGAACT TTGTCATATT 
GCAGAAACCA TGGCTAGAGG ATTGGCATAT TTACATGAGG ATATACCTGG CTTAAAAGAT 
GGCCACAAGC CTGCAATATC TCACAGGGAC ATAAAAAGTA AAAATGTGCT GTTGAAAAAC 
AATCTGACAG CTTGCATTGC TGACTTTGGG TTGGCCTTAA AGTTTGAGGC TGGCAAGTCT 
GCAGGTGACA CCCATGGCCA GGTTGGTACC CGGAGGTATA TGGCTCCAGA GGTGTTAGAG 
GGTGCTATAA ACTTCCAAAG GGACGCATTT CTGAGGATAG ATATGTACGC CATGGGATTA 
GTCCTGTGGG AACTGGCTTC TCGTTGTACT GCTGCAGATG GACCTGTAGA TGAGTACATG 
TTGCCATTTG AGGAGGAAAT TGGCCAGCAT CCATCTCTTG AAGATATGCA GGAAGTTGTT 
GTGCATAAAA AAAAGAGGCC CGTTTTAAGA GATTATTGGC AGAAACACGC AGGAATGGCA 
ATGCTCTGTG AAACGATAGA AGAATGCTGG GATCATGATG CAGAAGCCAG GTTATCAGCT 
GGATGTGTAG GTGAAAGAAT TACTCAGATG CAAAGACTAA CAAATATAAT TACTACAGAG 
GACATTGTAA CAGTGGTCAC AATGGTGACA AATGTTGACT TTCCTCCCAA AGAATCTAGT 
CTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008759925.1
CDS	87..1652
Translation	MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNANWERDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPEVYFCCCEGNMCNEKFSYFPEMEVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQHAFHIMIEDPGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL

Target ORF information:

RefSeq Version	XM_008761703.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus activin A receptor type 2A (Acvr2a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008761703.2

ORF Insert Sequence:

ATGGGAGCTG CTGCAAAGTT GGCGTTCGCC GTCTTTCTTA TCTCTTGCTC TTCAGGTGCT 
ATACTTGGCA GATCGGAAAC TCAGGAGTGT CTTTTCTTTA ATGCTAATTG GGAAAGAGAC 
AGAACCAATC AGACTGGTGT TGAGCCTTGC TATGGTGATA AAGACAAACG ACGACATTGT 
TTTGCTACCT GGAAGAATAT TTCTGGTTCC ATTGAAATAG TAAAGCAAGG TTGTTGGCTG 
GATGATATCA ACTGCTATGA CAGGACTGAT TGTATAGAAA AAAAAGACAG CCCTGAAGTG 
TACTTTTGTT GCTGTGAGGG CAATATGTGT AATGAAAAGT TCTCTTATTT TCCGGAGATG 
GAAGTCACAC AGCCCACATC AAATCCTGTT ACCCCGAAAC CACCCTACTA CAACATCCTG 
CTGTATTCCT TGGTACCACT TATGTTAATT GCGGGGATTG TCATTTGTGC GTTTTGGGTG 
TACAGACATC ACAAGATGGC CTACCCTCCT GTACTTGTTC CTACTCAGCA CGCCTTTCAT 
ATAATGATAG AGGACCCTGG ACCACCTCCA CCTTCCCCAT TACTAGGGTT GAAGCCATTG 
CAGCTATTGG AAGTGAAAGC AAGGGGAAGA TTTGGTTGTG TCTGGAAAGC CCAGTTGCTC 
AATGAGTATG TGGCTGTCAA AATATTTCCG ATACAGGACA AACAGTCCTG GCAGAATGAA 
TATGAAGTCT ATAGTTTACC TGGTATGAAG CATGAAAACA TACTACAGTT CATTGGTGCA 
GAGAAAAGAG GCACCAGTGT TGATGTGGAC CTGTGGCTAA TCACGGCTTT TCATGAAAAG 
GGCTCACTGT CAGACTTTCT TAAGGCTAAT GTGGTCTCTT GGAATGAACT TTGTCATATT 
GCAGAAACCA TGGCTAGAGG ATTGGCATAT TTACATGAGG ATATACCTGG CTTAAAAGAT 
GGCCACAAGC CTGCAATATC TCACAGGGAC ATAAAAAGTA AAAATGTGCT GTTGAAAAAC 
AATCTGACAG CTTGCATTGC TGACTTTGGG TTGGCCTTAA AGTTTGAGGC TGGCAAGTCT 
GCAGGTGACA CCCATGGCCA GGTTGGTACC CGGAGGTATA TGGCTCCAGA GGTGTTAGAG 
GGTGCTATAA ACTTCCAAAG GGACGCATTT CTGAGGATAG ATATGTACGC CATGGGATTA 
GTCCTGTGGG AACTGGCTTC TCGTTGTACT GCTGCAGATG GACCTGTAGA TGAGTACATG 
TTGCCATTTG AGGAGGAAAT TGGCCAGCAT CCATCTCTTG AAGATATGCA GGAAGTTGTT 
GTGCATAAAA AAAAGAGGCC CGTTTTAAGA GATTATTGGC AGAAACACGC AGGAATGGCA 
ATGCTCTGTG AAACGATAGA AGAATGCTGG GATCATGATG CAGAAGCCAG GTTATCAGCT 
GGATGTGTAG GTGAAAGAAT TACTCAGATG CAAAGACTAA CAAATATAAT TACTACAGAG 
GACATTGTAA CAGTGGTCAC AATGGTGACA AATGTTGACT TTCCTCCCAA AGAATCTAGT 
CTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Acvr2a ( NM_031571.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113759.1 Rattus norvegicus activin A receptor type 2A (Acvr2a), mRNA.

Price & Availability↑

CloneID	ORa08130
Clone ID Related Accession (Same CDS sequence)	NM_031571.2
Accession Version	NM_031571.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1542bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	activin receptor type-2A precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from S48190.1. On Feb 21, 2013 this sequence version replaced NM_031571.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L10639.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGGAGCTG CTGCAAAGTT GGCGTTCGCC GTCTTTCTTA TCTCTTGCTC TTCAGGTGCT 
ATACTTGGCA GATCGGAAAC TCAGGAGTGT CTTTTCTTTA ATGCTAATTG GGAAAGAGAC 
AGAACCAATC AGACTGGTGT TGAGCCTTGC TATGGTGATA AAGACAAACG ACGACATTGT 
TTTGCTACCT GGAAGAATAT TTCTGGTTCC ATTGAAATAG TAAAGCAAGG TTGTTGGCTG 
GATGATATCA ACTGCTATGA CAGGACTGAT TGTATAGAAA AAAAAGACAG CCCTGAAGTG 
TACTTTTGTT GCTGTGAGGG CAATATGTGT AATGAAAAGT TCTCTTATTT TCCGGAGATG 
GAAGTCACAC AGCCCACATC AAATCCTGTT ACCCCGAAAC CACCCTACTA CAACATCCTG 
CTGTATTCCT TGGTACCACT TATGTTAATT GCGGGGATTG TCATTTGTGC GTTTTGGGTG 
TACAGACATC ACAAGATGGC CTACCCTCCT GTACTTGTTC CTACTCAGGA CCCTGGACCA 
CCTCCACCTT CCCCATTACT AGGGTTGAAG CCATTGCAGC TATTGGAAGT GAAAGCAAGG 
GGAAGATTTG GTTGTGTCTG GAAAGCCCAG TTGCTCAATG AGTATGTGGC TATCAAAATA 
TTTCCGATAC AGGACAAACA GTCCTGGCAG AATGAATATG AAGTCTATAG TTTACCTGGG 
ATGAAGCATG AAAACATACT ACAGTTCATT GGTGCAGAGA AAAGAGGCAC CAGTGTTGAT 
GTGGACCTGT GGCTAATCAC GGCTTTTCAT GAAAAGGGCT CACTGTCAGA CTTTCTTAAG 
GCTAATGTGG TCTCTTGGAA TGAACTTTGT CATATTGCAG AAACCATGGC TAGAGGATTG 
GCATATTTAC ATGAGGATAT ACCTGGCTTA AAAGATGGCC ACAAGCCTGC AATATCTCAC 
AGGGACATCA AAAGTAAAAA TGTGCTGTTG AAAAACAATC TGACAGCTTG CATTGCTGAC 
TTTGGGTTGG CCTTAAAGTT TGAGGCTGGC AAGTCTGCAG GTGACACCCA TGGCCAGGTT 
GGTACCCGGA GGTATATGGC TCCAGAGGTG TTAGAGGGTG CTATAAACTT CCAAAGGGAC 
GCATTTCTGA GGATAGATAT GTACGCCATG GGATTAGTCC TGTGGGAACT GGCTTCTCGT 
TGTACTGCTG CAGATGGACC TGTAGATGAG TACATGTTGC CATTTGAGGA GGAAATTGGC 
CAGCATCCAT CTCTTGAAGA TATGCAGGAA GTTGTTGTGC ATAAAAAAAA GAGGCCCGTT 
TTAAGAGATT ATTGGCAGAA ACACGCAGGA ATGGCAATGC TCTGTGAAAC GATAGAAGAA 
TGCTGGGATC ATGATGCAGA AGCCAGGTTA TCAGCTGGAT GTGTAGGTGA AAGAATTACT 
CAGATGCAAA GACTAACAAA TATAATTACT ACAGAGGACA TTGTAACAGT GGTCACAATG 
GTGACAAATG TTGACTTTCC TCCCAAAGAA TCTAGTCTAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113759.1
CDS	22..1563
Translation	MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNANWERDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPEVYFCCCEGNMCNEKFSYFPEMEVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQDPGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAIKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL

Target ORF information:

RefSeq Version	NM_031571.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus activin A receptor type 2A (Acvr2a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031571.2

ORF Insert Sequence:

ATGGGAGCTG CTGCAAAGTT GGCGTTCGCC GTCTTTCTTA TCTCTTGCTC TTCAGGTGCT 
ATACTTGGCA GATCGGAAAC TCAGGAGTGT CTTTTCTTTA ATGCTAATTG GGAAAGAGAC 
AGAACCAATC AGACTGGTGT TGAGCCTTGC TATGGTGATA AAGACAAACG ACGACATTGT 
TTTGCTACCT GGAAGAATAT TTCTGGTTCC ATTGAAATAG TAAAGCAAGG TTGTTGGCTG 
GATGATATCA ACTGCTATGA CAGGACTGAT TGTATAGAAA AAAAAGACAG CCCTGAAGTG 
TACTTTTGTT GCTGTGAGGG CAATATGTGT AATGAAAAGT TCTCTTATTT TCCGGAGATG 
GAAGTCACAC AGCCCACATC AAATCCTGTT ACCCCGAAAC CACCCTACTA CAACATCCTG 
CTGTATTCCT TGGTACCACT TATGTTAATT GCGGGGATTG TCATTTGTGC GTTTTGGGTG 
TACAGACATC ACAAGATGGC CTACCCTCCT GTACTTGTTC CTACTCAGGA CCCTGGACCA 
CCTCCACCTT CCCCATTACT AGGGTTGAAG CCATTGCAGC TATTGGAAGT GAAAGCAAGG 
GGAAGATTTG GTTGTGTCTG GAAAGCCCAG TTGCTCAATG AGTATGTGGC TATCAAAATA 
TTTCCGATAC AGGACAAACA GTCCTGGCAG AATGAATATG AAGTCTATAG TTTACCTGGG 
ATGAAGCATG AAAACATACT ACAGTTCATT GGTGCAGAGA AAAGAGGCAC CAGTGTTGAT 
GTGGACCTGT GGCTAATCAC GGCTTTTCAT GAAAAGGGCT CACTGTCAGA CTTTCTTAAG 
GCTAATGTGG TCTCTTGGAA TGAACTTTGT CATATTGCAG AAACCATGGC TAGAGGATTG 
GCATATTTAC ATGAGGATAT ACCTGGCTTA AAAGATGGCC ACAAGCCTGC AATATCTCAC 
AGGGACATCA AAAGTAAAAA TGTGCTGTTG AAAAACAATC TGACAGCTTG CATTGCTGAC 
TTTGGGTTGG CCTTAAAGTT TGAGGCTGGC AAGTCTGCAG GTGACACCCA TGGCCAGGTT 
GGTACCCGGA GGTATATGGC TCCAGAGGTG TTAGAGGGTG CTATAAACTT CCAAAGGGAC 
GCATTTCTGA GGATAGATAT GTACGCCATG GGATTAGTCC TGTGGGAACT GGCTTCTCGT 
TGTACTGCTG CAGATGGACC TGTAGATGAG TACATGTTGC CATTTGAGGA GGAAATTGGC 
CAGCATCCAT CTCTTGAAGA TATGCAGGAA GTTGTTGTGC ATAAAAAAAA GAGGCCCGTT 
TTAAGAGATT ATTGGCAGAA ACACGCAGGA ATGGCAATGC TCTGTGAAAC GATAGAAGAA 
TGCTGGGATC ATGATGCAGA AGCCAGGTTA TCAGCTGGAT GTGTAGGTGA AAGAATTACT 
CAGATGCAAA GACTAACAAA TATAATTACT ACAGAGGACA TTGTAACAGT GGTCACAATG 
GTGACAAATG TTGACTTTCC TCCCAAAGAA TCTAGTCTAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolving New Skeletal Traits by cis-Regulatory Changes in Bone Morphogenetic Proteins.
Cell164(1-2)45-56(2016 Jan)
Indjeian VB,Kingman GA,Jones FC,Guenther CA,Grimwood J,Schmutz J,Myers RM,Kingsley DM

Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells.
The Journal of biological chemistry284(23)15794-804(2009 Jun)
Upton PD,Davies RJ,Trembath RC,Morrell NW

BMP-2/4 and BMP-6/7 differentially utilize cell surface receptors to induce osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells.
The Journal of biological chemistry283(30)20948-58(2008 Jul)
Lavery K,Swain P,Falb D,Alaoui-Ismaili MH

Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin.
Blood111(10)5195-204(2008 May)
Xia Y,Babitt JL,Sidis Y,Chung RT,Lin HY

Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development.
Developmental biology311(2)500-11(2007 Nov)
Andersson O,Bertolino P,Ib??ez CF

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Acvr2a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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