Nop53 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nop53
Entrez Gene ID	292624
Full Name	NOP53 ribosome biogenesis factor
Synonyms	Gltscr2
General protein information	Preferred Names NOP53 ribosome biogenesis factor Names glioma tumor suppressor candidate region gene 2 protein preS1 binding protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q21
Summary	human homolog regulates the phosphorylation and turnover of tumor suppressor PTEN [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_207591.1	NP_997474.1	glioma tumor suppressor candidate region gene 2 protein
NM_207591.2	NP_997474.1	glioma tumor suppressor candidate region gene 2 protein

Pathways from BioSystems

Homologies

	GLTSCR2	XP_001113326.1
Drosophila melanogaster (fruit fly)	CG1785	NP_572502.1
Saccharomyces cerevisiae (baker's yeast)	NOP53	NP_015179.1
Neurospora crassa	NCU05233	XP_961893.1
Xenopus tropicalis (tropical clawed frog)	gltscr2	XP_002939289.2
Homo sapiens (human)	GLTSCR2	NP_056525.2
Canis lupus familiaris (dog)	GLTSCR2	XP_005616435.1
Rattus norvegicus (Norway rat)	Gltscr2	NP_997474.1
Eremothecium gossypii	AGOS_ACR126W	NP_983528.1
Schizosaccharomyces pombe (fission yeast)	rrp16	NP_594732.1
Mus musculus (house mouse)	Gltscr2	NP_598592.2
Danio rerio (zebrafish)	gltscr2	NP_001073415.1
Magnaporthe oryzae (rice blast fungus)	MGG_04142	XP_003719688.1
Pan troglodytes (chimpanzee)	GLTSCR2	XP_001169866.2
Bos taurus (cattle)	GLTSCR2	NP_001033596.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000270	XP_310849.4
Caenorhabditis elegans (roundworm)	CELE_Y39B6A.33	NP_741664.1
Kluyveromyces lactis	KLLA0F11506g	XP_455604.1

Gene Ontology
Bibliography

Related articles in PubMed

GLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARF.
Lee S, Cho YE, Kim SH, Kim YJ, Park JH
Oncotarget8(10)16293-16302(2017 Mar)

PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway.
Chen H, Han L, Tsai H, Wang Z, Wu Y, Duo Y, Cao W, Chen L, Tan Z, Xu N, Huang X, Zhuang J, Huang L
Oncotarget7(50)83241-83257(2016 Dec)

PICT-1 triggers a pro-death autophagy through inhibiting rRNA transcription and AKT/mTOR/p70S6K signaling pathway.
Chen H, Duo Y, Hu B, Wang Z, Zhang F, Tsai H, Zhang J, Zhou L, Wang L, Wang X, Huang L
Oncotarget7(48)78747-78763(2016 Nov)

The nucleolar protein GLTSCR2 is required for efficient viral replication.
Wang P, Meng W, Han SC, Li CC, Wang XJ, Wang XJ
Scientific reports636226(2016 Nov)

The Nucleolar Protein GLTSCR2 Is an Upstream Negative Regulator of the Oncogenic Nucleophosmin-MYC Axis.
Kim JY, Cho YE, Park JH
The American journal of pathology185(7)2061-8(2015 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Nop53 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nop53 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa05567	NM_207591.2 Latest version!	Rattus norvegicus NOP53 ribosome biogenesis factor (Nop53), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$286.30 $409.00
View Old Accession Versions >>
ORa05567	NM_207591.1	Rattus norvegicus glioma tumor suppressor candidate region gene 2 (Gltscr2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$286.30 $409.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nop53 ( NM_207591.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_997474.1 Rattus norvegicus glioma tumor suppressor candidate region gene 2 (Gltscr2), mRNA.

Price & Availability↑

CloneID	ORa05567
Clone ID Related Accession (Same CDS sequence)	NM_207591.1 , NM_207591.2
Accession Version	NM_207591.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1449bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-31
Organism	Rattus norvegicus(Norway rat)
Product	glioma tumor suppressor candidate region gene 2 protein
Comment	PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY535002.1. On Aug 30, 2004 this sequence version replaced XM_214816.2. ##Evidence-Data-START## Transcript exon combination :: AY535002.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCTGCGG GTAGTAACAG AGGCGGTGAT AAGCGCGGCT CGAAAAGCCA GGCGGACTCT 
AACTTTCTGG GGCTGCGGCC CACCTCGGTG GATCCCGCTC TGAGGCGGCG GCGGCGGGGC 
CCCAGAAACA AGAAGCGCGG CTGGAGGAGG CTCGCTGAGG AGCCGCTGGG GCTAGAGGTA 
GACCAGTTCC TGGAAGATGT ACGGCTACAA GAGCGCACGA CCGGTGGCTT GTTGGCAGAG 
GCCCCAAATG AACAGCTCTT CTTCGTGGAC ACTGGACTCA AGAAAAAAGA ACCACGCAAG 
AAGAGGACCT GGGTCCAGAA GAAGTCAAAG CATCTCCAGA AACCCCTACG GGTTGACCTT 
GCCCTTGAGA ATCATTCTAA GATCCCTGCT CCCAAAGACA TCCTTGCACA CCAGGTCCCC 
AATGCCAAAA AGCTCAGGCG AAAGGAGGAG CTATGGGAGA AACTGGCAAA GCAGGGAGAG 
CTGCCCAGGG ATGTGCGCAA GGCACAGGCC CGGCTTCTTA ACCCTCCTGC ACCAAAGGCC 
AAACCTGGGC CCCAGGATAT CATTGAGCGG CCCTTCTATG ACCTCTGGAA CCCAAACAAT 
CCTCTGGATA AGCCTTTGAT CGGTCAGGAT GCATTTTTTC TGGAGCAGAC CAAGAAGAAA 
GGTGTGAGGC GGCCACCACG ACTCCACATC AAGCCTTCCC AGGTGCCTGC GGTGGAAGTG 
ATTCCTGCGG GAGCCTCCTA CAACCCAACC TTTGAAGATC ACCAGGCCTT GCTTCTAGAG 
GCCCATGAGG TGGAGCTGCA GCGTGAGAAA GAGGCAGAAA AGCTGGAGCG ACAGCTGGCC 
CTGCCCACTG CAGAGCAAGC TGCTACCCAG GAGTCCGTGT TTCGGGAGAT GTGTGAGGGC 
CTGCTCGAAG AGTCTGAGGA TGAGGATGGG CCAGGCTGTG CTGAGCAGCC AGAGGCTGAC 
GATGGGGCCA CTGAGACCTC ACCCACTGGT GCTGCTGGTC CTGAGAAGAG GATGGAGAAG 
AAGACAGAGC AGCAGCGGCG GCGGGAGAAG GCTGCTCGCA AGCTGCGGGT GCAGCAGGCT 
GCACTGAGGG CAGCCCGGCT TCAGCACCAA GAACTCTTCA GGCTACGTGG GATCAAGGCC 
CAGGTGGCCC GGAGGCTGGC AGAGCTGGCA CGCCGGAAGG AGCAGCGGCG CATACGGCGA 
CTGGCAGAGG CTGACAAACC CCGAAGGCTG GGACGGCTCA AGTACCAGGC CCCTGACATT 
GATGTGCAGC TCAGCTCTGA GCTATCTGAC TCACTCAGGA AACTGAAGCC AGAAGGTAAC 
ATTCTCCGAG ACAGGTTCAA AAGCTTCCAG AAGAGAAATA TGATTGAGCC CCGGGAACGA 
GCCAAGTTCA AGCGCAAATA CAAAGTGAAG CTGGTGGAGA AGCGGGCTTT CCGCGAGATT 
CAGTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997474.1
CDS	1..1449
Translation	MAAGSNRGGDKRGSKSQADSNFLGLRPTSVDPALRRRRRGPRNKKRGWRRLAEEPLGLEVDQFLEDVRLQERTTGGLLAEAPNEQLFFVDTGLKKKEPRKKRTWVQKKSKHLQKPLRVDLALENHSKIPAPKDILAHQVPNAKKLRRKEELWEKLAKQGELPRDVRKAQARLLNPPAPKAKPGPQDIIERPFYDLWNPNNPLDKPLIGQDAFFLEQTKKKGVRRPPRLHIKPSQVPAVEVIPAGASYNPTFEDHQALLLEAHEVELQREKEAEKLERQLALPTAEQAATQESVFREMCEGLLEESEDEDGPGCAEQPEADDGATETSPTGAAGPEKRMEKKTEQQRRREKAARKLRVQQAALRAARLQHQELFRLRGIKAQVARRLAELARRKEQRRIRRLAEADKPRRLGRLKYQAPDIDVQLSSELSDSLRKLKPEGNILRDRFKSFQKRNMIEPRERAKFKRKYKVKLVEKRAFREIQL

Target ORF information:

RefSeq Version	NM_207591.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus glioma tumor suppressor candidate region gene 2 (Gltscr2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_207591.1

ORF Insert Sequence:

ATGGCTGCGG GTAGTAACAG AGGCGGTGAT AAGCGCGGCT CGAAAAGCCA GGCGGACTCT 
AACTTTCTGG GGCTGCGGCC CACCTCGGTG GATCCCGCTC TGAGGCGGCG GCGGCGGGGC 
CCCAGAAACA AGAAGCGCGG CTGGAGGAGG CTCGCTGAGG AGCCGCTGGG GCTAGAGGTA 
GACCAGTTCC TGGAAGATGT ACGGCTACAA GAGCGCACGA CCGGTGGCTT GTTGGCAGAG 
GCCCCAAATG AACAGCTCTT CTTCGTGGAC ACTGGACTCA AGAAAAAAGA ACCACGCAAG 
AAGAGGACCT GGGTCCAGAA GAAGTCAAAG CATCTCCAGA AACCCCTACG GGTTGACCTT 
GCCCTTGAGA ATCATTCTAA GATCCCTGCT CCCAAAGACA TCCTTGCACA CCAGGTCCCC 
AATGCCAAAA AGCTCAGGCG AAAGGAGGAG CTATGGGAGA AACTGGCAAA GCAGGGAGAG 
CTGCCCAGGG ATGTGCGCAA GGCACAGGCC CGGCTTCTTA ACCCTCCTGC ACCAAAGGCC 
AAACCTGGGC CCCAGGATAT CATTGAGCGG CCCTTCTATG ACCTCTGGAA CCCAAACAAT 
CCTCTGGATA AGCCTTTGAT CGGTCAGGAT GCATTTTTTC TGGAGCAGAC CAAGAAGAAA 
GGTGTGAGGC GGCCACCACG ACTCCACATC AAGCCTTCCC AGGTGCCTGC GGTGGAAGTG 
ATTCCTGCGG GAGCCTCCTA CAACCCAACC TTTGAAGATC ACCAGGCCTT GCTTCTAGAG 
GCCCATGAGG TGGAGCTGCA GCGTGAGAAA GAGGCAGAAA AGCTGGAGCG ACAGCTGGCC 
CTGCCCACTG CAGAGCAAGC TGCTACCCAG GAGTCCGTGT TTCGGGAGAT GTGTGAGGGC 
CTGCTCGAAG AGTCTGAGGA TGAGGATGGG CCAGGCTGTG CTGAGCAGCC AGAGGCTGAC 
GATGGGGCCA CTGAGACCTC ACCCACTGGT GCTGCTGGTC CTGAGAAGAG GATGGAGAAG 
AAGACAGAGC AGCAGCGGCG GCGGGAGAAG GCTGCTCGCA AGCTGCGGGT GCAGCAGGCT 
GCACTGAGGG CAGCCCGGCT TCAGCACCAA GAACTCTTCA GGCTACGTGG GATCAAGGCC 
CAGGTGGCCC GGAGGCTGGC AGAGCTGGCA CGCCGGAAGG AGCAGCGGCG CATACGGCGA 
CTGGCAGAGG CTGACAAACC CCGAAGGCTG GGACGGCTCA AGTACCAGGC CCCTGACATT 
GATGTGCAGC TCAGCTCTGA GCTATCTGAC TCACTCAGGA AACTGAAGCC AGAAGGTAAC 
ATTCTCCGAG ACAGGTTCAA AAGCTTCCAG AAGAGAAATA TGATTGAGCC CCGGGAACGA 
GCCAAGTTCA AGCGCAAATA CAAAGTGAAG CTGGTGGAGA AGCGGGCTTT CCGCGAGATT 
CAGTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nop53 ( NM_207591.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_997474.1 Rattus norvegicus NOP53 ribosome biogenesis factor (Nop53), mRNA.

Price & Availability↑

CloneID	ORa05567
Clone ID Related Accession (Same CDS sequence)	NM_207591.1 , NM_207591.2
Accession Version	NM_207591.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1449bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-03
Organism	Rattus norvegicus(Norway rat)
Product	glioma tumor suppressor candidate region gene 2 protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07002624.1. On May 12, 2017 this sequence version replaced NM_207591.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FQ212888.1, FQ214363.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCGG GTAGTAACAG AGGCGGTGAT AAGCGCGGCT CGAAAAGCCA GGCGGACTCT 
AACTTTCTGG GGCTGCGGCC CACCTCGGTG GATCCCGCTC TGAGGCGGCG GCGGCGGGGC 
CCCAGAAACA AGAAGCGCGG CTGGAGGAGG CTCGCTGAGG AGCCGCTGGG GCTAGAGGTA 
GACCAGTTCC TGGAAGATGT ACGGCTACAA GAGCGCACGA CCGGTGGCTT GTTGGCAGAG 
GCCCCAAATG AACAGCTCTT CTTCGTGGAC ACTGGACTCA AGAAAAAAGA ACCACGCAAG 
AAGAGGACCT GGGTCCAGAA GAAGTCAAAG CATCTCCAGA AACCCCTACG GGTTGACCTT 
GCCCTTGAGA ATCATTCTAA GATCCCTGCT CCCAAAGACA TCCTTGCACA CCAGGTCCCC 
AATGCCAAAA AGCTCAGGCG AAAGGAGGAG CTATGGGAGA AACTGGCAAA GCAGGGAGAG 
CTGCCCAGGG ATGTGCGCAA GGCACAGGCC CGGCTTCTTA ACCCTCCTGC ACCAAAGGCC 
AAACCTGGGC CCCAGGATAT CATTGAGCGG CCCTTCTATG ACCTCTGGAA CCCAAACAAT 
CCTCTGGATA AGCCTTTGAT CGGTCAGGAT GCATTTTTTC TGGAGCAGAC CAAGAAGAAA 
GGTGTGAGGC GGCCACCACG ACTCCACATC AAGCCTTCCC AGGTGCCTGC GGTGGAAGTG 
ATTCCTGCGG GAGCCTCCTA CAACCCAACC TTTGAAGATC ACCAGGCCTT GCTTCTAGAG 
GCCCATGAGG TGGAGCTGCA GCGTGAGAAA GAGGCAGAAA AGCTGGAGCG ACAGCTGGCC 
CTGCCCACTG CAGAGCAAGC TGCTACCCAG GAGTCCGTGT TTCGGGAGAT GTGTGAGGGC 
CTGCTCGAAG AGTCTGAGGA TGAGGATGGG CCAGGCTGTG CTGAGCAGCC AGAGGCTGAC 
GATGGGGCCA CTGAGACCTC ACCCACTGGT GCTGCTGGTC CTGAGAAGAG GATGGAGAAG 
AAGACAGAGC AGCAGCGGCG GCGGGAGAAG GCTGCTCGCA AGCTGCGGGT GCAGCAGGCT 
GCACTGAGGG CAGCCCGGCT TCAGCACCAA GAACTCTTCA GGCTACGTGG GATCAAGGCC 
CAGGTGGCCC GGAGGCTGGC AGAGCTGGCA CGCCGGAAGG AGCAGCGGCG CATACGGCGA 
CTGGCAGAGG CTGACAAACC CCGAAGGCTG GGACGGCTCA AGTACCAGGC CCCTGACATT 
GATGTGCAGC TCAGCTCTGA GCTATCTGAC TCACTCAGGA AACTGAAGCC AGAAGGTAAC 
ATTCTCCGAG ACAGGTTCAA AAGCTTCCAG AAGAGAAATA TGATTGAGCC CCGGGAACGA 
GCCAAGTTCA AGCGCAAATA CAAAGTGAAG CTGGTGGAGA AGCGGGCTTT CCGCGAGATT 
CAGTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997474.1
CDS	32..1480
Translation	MAAGSNRGGDKRGSKSQADSNFLGLRPTSVDPALRRRRRGPRNKKRGWRRLAEEPLGLEVDQFLEDVRLQERTTGGLLAEAPNEQLFFVDTGLKKKEPRKKRTWVQKKSKHLQKPLRVDLALENHSKIPAPKDILAHQVPNAKKLRRKEELWEKLAKQGELPRDVRKAQARLLNPPAPKAKPGPQDIIERPFYDLWNPNNPLDKPLIGQDAFFLEQTKKKGVRRPPRLHIKPSQVPAVEVIPAGASYNPTFEDHQALLLEAHEVELQREKEAEKLERQLALPTAEQAATQESVFREMCEGLLEESEDEDGPGCAEQPEADDGATETSPTGAAGPEKRMEKKTEQQRRREKAARKLRVQQAALRAARLQHQELFRLRGIKAQVARRLAELARRKEQRRIRRLAEADKPRRLGRLKYQAPDIDVQLSSELSDSLRKLKPEGNILRDRFKSFQKRNMIEPRERAKFKRKYKVKLVEKRAFREIQL

Target ORF information:

RefSeq Version	NM_207591.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus NOP53 ribosome biogenesis factor (Nop53), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_207591.2

ORF Insert Sequence:

ATGGCTGCGG GTAGTAACAG AGGCGGTGAT AAGCGCGGCT CGAAAAGCCA GGCGGACTCT 
AACTTTCTGG GGCTGCGGCC CACCTCGGTG GATCCCGCTC TGAGGCGGCG GCGGCGGGGC 
CCCAGAAACA AGAAGCGCGG CTGGAGGAGG CTCGCTGAGG AGCCGCTGGG GCTAGAGGTA 
GACCAGTTCC TGGAAGATGT ACGGCTACAA GAGCGCACGA CCGGTGGCTT GTTGGCAGAG 
GCCCCAAATG AACAGCTCTT CTTCGTGGAC ACTGGACTCA AGAAAAAAGA ACCACGCAAG 
AAGAGGACCT GGGTCCAGAA GAAGTCAAAG CATCTCCAGA AACCCCTACG GGTTGACCTT 
GCCCTTGAGA ATCATTCTAA GATCCCTGCT CCCAAAGACA TCCTTGCACA CCAGGTCCCC 
AATGCCAAAA AGCTCAGGCG AAAGGAGGAG CTATGGGAGA AACTGGCAAA GCAGGGAGAG 
CTGCCCAGGG ATGTGCGCAA GGCACAGGCC CGGCTTCTTA ACCCTCCTGC ACCAAAGGCC 
AAACCTGGGC CCCAGGATAT CATTGAGCGG CCCTTCTATG ACCTCTGGAA CCCAAACAAT 
CCTCTGGATA AGCCTTTGAT CGGTCAGGAT GCATTTTTTC TGGAGCAGAC CAAGAAGAAA 
GGTGTGAGGC GGCCACCACG ACTCCACATC AAGCCTTCCC AGGTGCCTGC GGTGGAAGTG 
ATTCCTGCGG GAGCCTCCTA CAACCCAACC TTTGAAGATC ACCAGGCCTT GCTTCTAGAG 
GCCCATGAGG TGGAGCTGCA GCGTGAGAAA GAGGCAGAAA AGCTGGAGCG ACAGCTGGCC 
CTGCCCACTG CAGAGCAAGC TGCTACCCAG GAGTCCGTGT TTCGGGAGAT GTGTGAGGGC 
CTGCTCGAAG AGTCTGAGGA TGAGGATGGG CCAGGCTGTG CTGAGCAGCC AGAGGCTGAC 
GATGGGGCCA CTGAGACCTC ACCCACTGGT GCTGCTGGTC CTGAGAAGAG GATGGAGAAG 
AAGACAGAGC AGCAGCGGCG GCGGGAGAAG GCTGCTCGCA AGCTGCGGGT GCAGCAGGCT 
GCACTGAGGG CAGCCCGGCT TCAGCACCAA GAACTCTTCA GGCTACGTGG GATCAAGGCC 
CAGGTGGCCC GGAGGCTGGC AGAGCTGGCA CGCCGGAAGG AGCAGCGGCG CATACGGCGA 
CTGGCAGAGG CTGACAAACC CCGAAGGCTG GGACGGCTCA AGTACCAGGC CCCTGACATT 
GATGTGCAGC TCAGCTCTGA GCTATCTGAC TCACTCAGGA AACTGAAGCC AGAAGGTAAC 
ATTCTCCGAG ACAGGTTCAA AAGCTTCCAG AAGAGAAATA TGATTGAGCC CCGGGAACGA 
GCCAAGTTCA AGCGCAAATA CAAAGTGAAG CTGGTGGAGA AGCGGGCTTT CCGCGAGATT 
CAGTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

GLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARF.
Oncotarget8(10)16293-16302(2017 Mar)
Lee S,Cho YE,Kim SH,Kim YJ,Park JH

PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway.
Oncotarget7(50)83241-83257(2016 Dec)
Chen H,Han L,Tsai H,Wang Z,Wu Y,Duo Y,Cao W,Chen L,Tan Z,Xu N,Huang X,Zhuang J,Huang L

PICT-1 triggers a pro-death autophagy through inhibiting rRNA transcription and AKT/mTOR/p70S6K signaling pathway.
Oncotarget7(48)78747-78763(2016 Nov)
Chen H,Duo Y,Hu B,Wang Z,Zhang F,Tsai H,Zhang J,Zhou L,Wang L,Wang X,Huang L

The nucleolar protein GLTSCR2 is required for efficient viral replication.
Scientific reports636226(2016 Nov)
Wang P,Meng W,Han SC,Li CC,Wang XJ,Wang XJ

The Nucleolar Protein GLTSCR2 Is an Upstream Negative Regulator of the Oncogenic Nucleophosmin-MYC Axis.
The American journal of pathology185(7)2061-8(2015 Jul)
Kim JY,Cho YE,Park JH

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Nop53 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

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