Stmn3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Stmn3
Entrez Gene ID	29246
Full Name	stathmin 3
Synonyms	Sclip
General protein information	Preferred Names stathmin 3 Names stathmin-3 SCG10-like protein scgn10 like-protein stathmin-like 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q43
Summary	plays a role in microtubule organization [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_024346.1	NP_077322.1	stathmin-3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	STMN3	XP_003953850.1
Canis lupus familiaris (dog)	STMN3	XP_005635352.1
Mus musculus (house mouse)	Stmn3	NP_033159.1
Gallus gallus (chicken)	STMN3	NP_001004393.1
Danio rerio (zebrafish)	LOC798970	XP_001339376.4
Bos taurus (cattle)	STMN3	NP_001077135.1
Homo sapiens (human)	STMN3	NP_056978.2
Rattus norvegicus (Norway rat)	Stmn3	NP_077322.1

Gene Ontology
Bibliography

Related articles in PubMed

Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos.
Cui W, Dai X, Marcho C, Han Z, Zhang K, Tremblay KD, Mager J
Scientific reports637396(2016 Nov)

Specific serine-proline phosphorylation and glycogen synthase kinase 3?-directed subcellular targeting of stathmin 3/Sclip in neurons.
Devaux S, Poulain FE, Devignot V, Lachkar S, Irinopoulou T, Sobel A
The Journal of biological chemistry287(26)22341-53(2012 Jun)

Subcellular Golgi localization of stathmin family proteins is promoted by a specific set of DHHC palmitoyl transferases.
Levy AD, Devignot V, Fukata Y, Fukata M, Sobel A, Chauvin S
Molecular biology of the cell22(11)1930-42(2011 Jun)

SCLIP is crucial for the formation and development of the Purkinje cell dendritic arbor.
Poulain FE, Chauvin S, Wehrl? R, Desclaux M, Mallet J, Vodjdani G, Dusart I, Sobel A
The Journal of neuroscience : the official journal of the Society for Neuroscience28(29)7387-98(2008 Jul)

The "SCG10-LIke Protein" SCLIP is a novel regulator of axonal branching in hippocampal neurons, unlike SCG10.
Poulain FE, Sobel A
Molecular and cellular neurosciences34(2)137-46(2007 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Specific serine-proline phosphorylation and glycogen synthase kinase 3beta-directed subcellular targeting of stathmin 3/Sclip in neurons
Title: Specific serine-proline phosphorylation and glycogen synthase kinase 3?-directed subcellular targeting of stathmin 3/Sclip in neurons.

palmitoylation of stathmins 2 and 3 likely occurs at the Golgi and is crucial for their specific subcellular localization and trafficking
Title: Subcellular Golgi localization of stathmin family proteins is promoted by a specific set of DHHC palmitoyl transferases.

SCLIP specifically accumulates in the growing dendrites of Purkinje cells (PC)during cerebellar development and is critical for both the formation and development of PC dendritic arbors at early and late stages of postnatal dendritogenesis.
Title: SCLIP is crucial for the formation and development of the Purkinje cell dendritic arbor.

A novel function for SCLIP in axonal morphogenesis, our results demonstrate for the first time that stathmin family proteins fulfill different and complementary roles during neuronal differentiation.
Title: The "SCG10-LIke Protein" SCLIP is a novel regulator of axonal branching in hippocampal neurons, unlike SCG10.

Clusterin interacts with SCLIP in PC12 cells and the interaction may act as an important modulator during neuronal differentiation.
Title: Clusterin interacts with SCLIP (SCG10-like protein) and promotes neurite outgrowth of PC12 cells.

The following Stmn3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Stmn3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06900	NM_024346.1 Latest version!	Rattus norvegicus stathmin 3 (Stmn3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Stmn3 ( NM_024346.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_077322.1 Rattus norvegicus stathmin 3 (Stmn3), mRNA.

Price & Availability↑

CloneID	ORa06900
Clone ID Related Accession (Same CDS sequence)	NM_024346.1
Accession Version	NM_024346.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 543bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Rattus norvegicus(Norway rat)
Product	stathmin-3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY004290.1. ##Evidence-Data-START## Transcript exon combination :: AY004290.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCCAGCA CCGTATCTGC CTACAAGGAG AAGATGAAGG AGCTATCTGT GCTGTCGCTC 
ATCTGTTCCT GCTTCTACTC GCAGCCTCAC CCGAACACCA TCTACCAGTA TGGGGATATG 
GAAGTGAAGC AGCTGGATAA GCGGGCCTCT GGCCAGAGCT TCGAGGTCAT CCTCAAGTCT 
CCTTCTGACC TATCTCCAGA GAGCCCTGTG CTCTCTTCTC CTCCCAAGAG GAAGGATGCT 
TCCTTGGAAG AGCTGCAGAA GCGGCTGGAG GCAGCTGAGG AGCGGAGGAA GACTCAGGAG 
GCTCAGGTGC TGAAGCAGCT GGCAGAGCGA CGTGAGCATG AGCGGGAGGT GCTGCACAAG 
GCGCTGGAAG AAAACAATAA CTTTAGCCCC CTGGCGGAGG AGAAGCTCAA CTACAAGATG 
GAGCTGAGCA AGGAGATTCG CGAGGCGCAC CTGGCGGCGC TGCGCGAGCG GCTGCGTGAG 
AAGGAACTGC ACGCTGCTGA GGTGCGCAGG AACAAGGAGC AGCGGGAGGA AATGTCTGGC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_077322.1
CDS	221..763
Translation	MASTVSAYKEKMKELSVLSLICSCFYSQPHPNTIYQYGDMEVKQLDKRASGQSFEVILKSPSDLSPESPVLSSPPKRKDASLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSPLAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG

Target ORF information:

RefSeq Version	NM_024346.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus stathmin 3 (Stmn3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024346.1

ORF Insert Sequence:

ATGGCCAGCA CCGTATCTGC CTACAAGGAG AAGATGAAGG AGCTATCTGT GCTGTCGCTC 
ATCTGTTCCT GCTTCTACTC GCAGCCTCAC CCGAACACCA TCTACCAGTA TGGGGATATG 
GAAGTGAAGC AGCTGGATAA GCGGGCCTCT GGCCAGAGCT TCGAGGTCAT CCTCAAGTCT 
CCTTCTGACC TATCTCCAGA GAGCCCTGTG CTCTCTTCTC CTCCCAAGAG GAAGGATGCT 
TCCTTGGAAG AGCTGCAGAA GCGGCTGGAG GCAGCTGAGG AGCGGAGGAA GACTCAGGAG 
GCTCAGGTGC TGAAGCAGCT GGCAGAGCGA CGTGAGCATG AGCGGGAGGT GCTGCACAAG 
GCGCTGGAAG AAAACAATAA CTTTAGCCCC CTGGCGGAGG AGAAGCTCAA CTACAAGATG 
GAGCTGAGCA AGGAGATTCG CGAGGCGCAC CTGGCGGCGC TGCGCGAGCG GCTGCGTGAG 
AAGGAACTGC ACGCTGCTGA GGTGCGCAGG AACAAGGAGC AGCGGGAGGA AATGTCTGGC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos.
Scientific reports637396(2016 Nov)
Cui W,Dai X,Marcho C,Han Z,Zhang K,Tremblay KD,Mager J

Specific serine-proline phosphorylation and glycogen synthase kinase 3?-directed subcellular targeting of stathmin 3/Sclip in neurons.
The Journal of biological chemistry287(26)22341-53(2012 Jun)
Devaux S,Poulain FE,Devignot V,Lachkar S,Irinopoulou T,Sobel A

Subcellular Golgi localization of stathmin family proteins is promoted by a specific set of DHHC palmitoyl transferases.
Molecular biology of the cell22(11)1930-42(2011 Jun)
Levy AD,Devignot V,Fukata Y,Fukata M,Sobel A,Chauvin S

SCLIP is crucial for the formation and development of the Purkinje cell dendritic arbor.
The Journal of neuroscience : the official journal of the Society for Neuroscience28(29)7387-98(2008 Jul)
Poulain FE,Chauvin S,Wehrl? R,Desclaux M,Mallet J,Vodjdani G,Dusart I,Sobel A

The "SCG10-LIke Protein" SCLIP is a novel regulator of axonal branching in hippocampal neurons, unlike SCG10.
Molecular and cellular neurosciences34(2)137-46(2007 Feb)
Poulain FE,Sobel A

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Stmn3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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