Thbs2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Thbs2
Entrez Gene ID	292406
Full Name	thrombospondin 2
Synonyms	TSP-2
General protein information	Preferred Names thrombospondin 2 Names thrombospondin-2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001169138.1	NP_001162609.1	thrombospondin-2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	THBS2	NP_003238.2
	THBS2	XP_001096616.2
Mus musculus (house mouse)	Thbs2	NP_035711.2
Gallus gallus (chicken)	THBS2	NP_001001755.1
Danio rerio (zebrafish)	LOC100535241	XP_003199793.2
Danio rerio (zebrafish)	thbs2b	XP_694690.6
Pan troglodytes (chimpanzee)	THBS2	XP_003311640.2
Canis lupus familiaris (dog)	THBS2	NP_001184085.1
Danio rerio (zebrafish)	thbs2a	XP_005157071.1
Bos taurus (cattle)	THBS2	NP_789861.1
Rattus norvegicus (Norway rat)	Thbs2	NP_001162609.1
Xenopus tropicalis (tropical clawed frog)	thbs2	XP_002931559.2

Gene Ontology
Bibliography

Related articles in PubMed

Macroglia-derived thrombospondin 2 regulates alterations of presynaptic proteins of retinal neurons following elevated hydrostatic pressure.
Wang S, Hu T, Wang Z, Li N, Zhou L, Liao L, Wang M, Liao L, Wang H, Zeng L, Fan C, Zhou H, Xiong K, Huang J, Chen D
PloS one12(9)e0185388(2017)

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Barallobre-Barreiro J, Oklu R, Lynch M, Fava M, Baig F, Yin X, Barwari T, Potier DN, Albadawi H, Jahangiri M, Porter KE, Watkins MT, Misra S, Stoughton J, Mayr M
Cardiovascular research110(3)419-30(2016 06)

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A, Mayr M
Circulation research113(10)1138-47(2013 Oct)

Distribution of thrombospondins and their neuronal receptor ?2?1 in the rat retina.
Huang J, Zhou L, Wang H, Luo J, Zeng L, Xiong K, Chen D
Experimental eye research11136-49(2013 Jun)

Thrombin promotes the expression of thrombospondin-1 and -2 in a rat model of intracerebral hemorrhage.
Yang AL, Zhou HJ, Lin Y, Luo JK, Cui HJ, Tang T, Yang QD
Journal of the neurological sciences323(1-2)141-6(2012 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The expression levels of glial fibrillary acidic protein (the marker of activated macroglia cells), thrombospondin 2, alpha2delta-1 and presynaptic proteins were increased following elevated hydrostatic pressure in mixed cultures, but the expression levels of postsynaptic proteins were not changed.
Title: Macroglia-derived thrombospondin 2 regulates alterations of presynaptic proteins of retinal neurons following elevated hydrostatic pressure.

In the adult rat retina, TSP2, but not TSP1, secreted by glial cells may be involved in the synaptic plastic process after retinal injury through binding to its neuronal receptor alpha2delta1.
Title: Distribution of thrombospondins and their neuronal receptor ?2?1 in the rat retina.

Intracerebral hemorrhage induced an increase in the expression of TSP-2 mRNA. Thrombin induced TSP-2 expression in the blood vessels around the ICH.
Title: Thrombin promotes the expression of thrombospondin-1 and -2 in a rat model of intracerebral hemorrhage.

intracerebral hemorrhage can alter the expression of TSP-1 and TSP-2, which may be involved in modulating angiogenesis in brains following intracerebral hemorrhage
Title: Alteration of thrombospondin-1 and -2 in rat brains following experimental intracerebral hemorrhage. Laboratory investigation.

Expression of mRNA for thrombospondins (TSP-1, TSP-2, TSP-4) was greater than 5-fold higher in vena cava versus thoracic aorta.
Title: Differential expression of pancreatitis-associated protein and thrombospondins in arterial versus venous tissues.

The following Thbs2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Thbs2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06077	NM_001169138.1 Latest version!	Rattus norvegicus thrombospondin 2 (Thbs2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Thbs2 ( NM_001169138.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001162609.1 Rattus norvegicus thrombospondin 2 (Thbs2), mRNA.

Price & Availability↑

CloneID	ORa06077
Clone ID Related Accession (Same CDS sequence)	NM_001169138.1
Accession Version	NM_001169138.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-23
Organism	Rattus norvegicus(Norway rat)
Product	thrombospondin-2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07001762.1. On or before Dec 18, 2009 this sequence version replaced XM_001055515.1, XM_214778.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCTGGG CACTGGCCCT GCTGGCTCTG GGCATAGGGC CAAGAGCTTA CGCTGGTGAC 
CACGGCGAGG ACACAGCATT TGACCTTTTC AGCATCAGCA ACATTAACCG GAAGACCATC 
GGTGCCAAGC AGTTCCGAGG GCCCGACCCC GGTGTGCCCG CCTACCGTTT TGTCCGGTTT 
GACTACGTCC CCCCAGTGAA TACAGACGAC CTCAACAGGA TCGTTAAGCT TGCAAGGAGA 
AAGGAGGGCT TCTTCCTCAC AGCCCAGCTG AAGCAGGACC GCAAGTCTCG GGGAACACTC 
CTGGTGTTGG AAGGTCCCGG CACCTCCCAG AGGCAGTTTG AGATTGTGTC CAATGGCCCA 
GGGGATACCT TGGACCTCAA CTACTGGGTA GAAGGCCACC AGCATACCAA CTTCCTGGAG 
GATGTGGGTC TGGCTGACTC CCAGTGGAAG AATGTGACTG TGCAGGTGGC CAGTGACACC 
TATAGCCTGT ATGTGGGCTG TGATCTTATT GACAGTGTCA CCCTGGAAGA ACCCTTCTAT 
GAGCAGCTGG AAGCAGACAA GAGCAGGATG TACGTGGCCA AGGGTGCATC TCGAGAGAGT 
CACTTCAGGG GCTTGCTGCA GAATGTCCAT CTCGTGTTTG CAGATTCTGT GGAAGATATT 
CTAAGCAAGA AAGGCTGTCA ACACAGCCAG GGAGCTGAAG TCAACACCAT CAGTGAACAT 
ACAGAGACAC TCCACCTGAG CCCTCACATC ACCACAGATC TGGTGGTCCA GGGTGTGGAG 
AAGGCACAGG AGGTGTGTAC GCACTCCTGT GAAGAGCTGA GCAACATGAT GAACGAGCTG 
TCCGGATTGC ACGTCATGGT GAACCAGCTG AGCAAGAACC TGGAGAGAGT GTCTAGCGAT 
AACCAGTTCC TTTTGGAGCT CATTGGGGGC CCTCTGAAGA CAAGAAACAT GTCGGCCTGT 
GTGCAGGAGG GACGGATCTT TGCAGAAAAC GAAACCTGGG TTGTGGATAG TTGTACCACC 
TGCACCTGCA AGAAATTTAA AACAGTCTGC AATCAAATCA CCTGCTCACC TGCAACTTGT 
GCCAACCCAT CTTTGGTGGA AGGCGAGTGC TGTCCATCCT GTTCCCACTC TGCAGACAAC 
GATGAGGGCT GGTCTCCGTG GGCAGAGTGG ACCGAGTGTT CTGTCACCTG TGGCTCTGGG 
ACCCAGCAGA GAGGCCGGTC TTGTGATGTC ACCAGCAACA CCTGCCTGGG CCCCTCCATT 
CAGACAAGGA CATGCAGTTT GGGCAAATGT GATACGAGAA TCCGTCAGAA TGGAGGCTGG 
AGTCACTGGT CACCCTGGTC TTCGTGCTCC GTGACTTGTG GAGTTGGCAA TGTCACCCGC 
ATACGTCTCT GCAACTCACC AGTGCCCCAA ATGGGTGGCA AGAACTGCAA GGGCAGTGGC 
CGGGAAACCA AGGCCTGCCA GCGTGCTCCA TGCCCAATTG ATGGCCGCTG GAGCCCCTGG 
TCCCCTTGGT CAGCCTGCAC AGTTACCTGT GCTGGAGGGA TCCGTGAGCG CACACGTGTT 
TGCAACAGCC CTGAGCCCCA GTATGGAGGG AAGGATTGTG TCGGGGATGT GACAGAACAC 
CAAATGTGCA ACAAGAGGAG CTGCCCTATT GATGGATGCC TATCCAACCC GTGTTTCCCT 
GGAGCCAAGT GCAACAGCTT CCCCGATGGC TCCTGGTCCT GTGGTTCCTG CCCAGTGGGC 
TTTCTGGGCA ATGGCACCCA CTGTGAGGAC CTGGATGAGT GTGCTGTGGT CGCAGATATC 
TGCTTCTCAA TTAACAAAGC TTCCCGCTGT GTCAACACCA ACCCTGGCTT CCACTGCCTG 
CCTTGTCCGC CACGCTACAA GGGGACCCAA CCCTTCGGGA TTGGCCTGGA GGATGCTAAA 
ACAGAAAAAC AAGTATGTGA GCCAGAGAAT CCGTGCAAGG ACAAGACTCA CAACTGCCAC 
AAGCATGCAG AGTGCATCTA CCTGGGCCAC TTCAGTGACC CCATGTACAA GTGCGAGTGC 
CAGACTGGCT ATGCAGGTGA TGGGCTCATC TGCGGGGAGG ACTCAGACCT GGACGGTTGG 
CCCAACAGCA ACCTGGTGTG TGCTACCAAT GCCACCTACC ACTGCGTCAA GGACAACTGC 
CCCAAACTGC CAAATTCTGG GCAGGAGGAT TTTGATAAGG ACGGAATCGG AGATGCTTGC 
GACGAGGACG ATGATAACGA CGGCGTGAGC GATGAGAAGG ACAATTGCCC ACTTCTCTTC 
AATCCCCGCC AATTAGACTA TGATAAGGAT GAGGTTGGAG ACCGCTGTGA CAATTGCCCC 
TATGTGCACA ACCAAGCACA GATCGACACG GACAACAACG GTGAAGGGGA CGCCTGCTCT 
GTGGATATCG ACGGGGATGA TGTTTTCAAT GAGCGAGACA ATTGCCCGTA TGTCTACAAC 
ACTGACCAGA GAGACACAGA CGGTGACGGC GTTGGGGACC ACTGTGACAA CTGTCCTCTG 
ATGCATAACC CAGATCAGAT GGATCAGGAC AATGATCTCG TTGGAGACCA GTGTGATAAC 
AATGAGGACA TAGATGATGA CGGCCACCAG AACAACCAAG ACAACTGCCC ATACATCTCC 
AACTCCAACC AGGCTGACCA TGACAATGAC GGCAAGGGGG ATGCCTGTGA CTCCGATGAT 
GACAACGATG GTGTTCCAGA TGACAGGGAC AACTGCAGGC TTGTGTTCAA CCCCGACCAG 
GAAGACTCGG ATGGCGACGG CCGAGGTGAT ATTTGTAAAG ATGACTTTGA CAATGATAAT 
GTCCCAGATA TTGATGACGT GTGCCCCGAG AACAATGCCA TCACCGAGAC AGACTTCAGA 
AACTTTCAGA TGGTCCCTCT GGATCCCAAG GGGACCACAC AAATTGATCC CAACTGGGTA 
ATTCGTCACC AAGGCAAAGA GCTGGTGCAG ACAGCAAACT CGGACCCTGG CATCGCCGTA 
GGTTTCGATG AGTTTGGGTC TGTGGACTTC AGCGGCACTT TCTATGTCAA CACTGACCGG 
GACGATGACT ACGCCGGCTT CGTCTTTGGC TATCAGTCAA GCAGCCGCTT CTATGTGGTG 
ATGTGGAAGC AGGTGACCCA GACCTACTGG GAAGACAAGC CCAGTCGGGC TTACGGCTAC 
TCTGGTGTGT CACTCAAAGT AGTAAACTCC ACGACTGGTA CTGGCGAGCA CCTGAGGAAT 
GCCCTGTGGC ACACGGGAAA CACGGAAGGC CAGGTTCGAA CTCTATGGCA TGACCCCAAA 
AACATTGGCT GGAAGGACTA CACCGCCTAC AGGTGGCATC TGATTCACAG GCCTAAGACA 
GGCTACATGA GAGTCTTAGT GCATGAAGGA AAGCAGGTCA TGGCTGACTC AGGACCAATT 
TATGACCAAA CTTATGCTGG TGGACGGCTG GGTCTGTTTG TCTTCTCCCA AGAAATGGTC 
TACTTCTCAG ACCTCAAGTA TGAGTGCAGA GATGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001162609.1
CDS	227..3745
Translation	MLWALALLALGIGPRAYAGDHGEDTAFDLFSISNINRKTIGAKQFRGPDPGVPAYRFVRFDYVPPVNTDDLNRIVKLARRKEGFFLTAQLKQDRKSRGTLLVLEGPGTSQRQFEIVSNGPGDTLDLNYWVEGHQHTNFLEDVGLADSQWKNVTVQVASDTYSLYVGCDLIDSVTLEEPFYEQLEADKSRMYVAKGASRESHFRGLLQNVHLVFADSVEDILSKKGCQHSQGAEVNTISEHTETLHLSPHITTDLVVQGVEKAQEVCTHSCEELSNMMNELSGLHVMVNQLSKNLERVSSDNQFLLELIGGPLKTRNMSACVQEGRIFAENETWVVDSCTTCTCKKFKTVCNQITCSPATCANPSLVEGECCPSCSHSADNDEGWSPWAEWTECSVTCGSGTQQRGRSCDVTSNTCLGPSIQTRTCSLGKCDTRIRQNGGWSHWSPWSSCSVTCGVGNVTRIRLCNSPVPQMGGKNCKGSGRETKACQRAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKDCVGDVTEHQMCNKRSCPIDGCLSNPCFPGAKCNSFPDGSWSCGSCPVGFLGNGTHCEDLDECAVVADICFSINKASRCVNTNPGFHCLPCPPRYKGTQPFGIGLEDAKTEKQVCEPENPCKDKTHNCHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDLDGWPNSNLVCATNATYHCVKDNCPKLPNSGQEDFDKDGIGDACDEDDDNDGVSDEKDNCPLLFNPRQLDYDKDEVGDRCDNCPYVHNQAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPLMHNPDQMDQDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNSNQADHDNDGKGDACDSDDDNDGVPDDRDNCRLVFNPDQEDSDGDGRGDICKDDFDNDNVPDIDDVCPENNAITETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDKPSRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTEGQVRTLWHDPKNIGWKDYTAYRWHLIHRPKTGYMRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDA

Target ORF information:

RefSeq Version	NM_001169138.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus thrombospondin 2 (Thbs2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001169138.1

ORF Insert Sequence:

ATGCTCTGGG CACTGGCCCT GCTGGCTCTG GGCATAGGGC CAAGAGCTTA CGCTGGTGAC 
CACGGCGAGG ACACAGCATT TGACCTTTTC AGCATCAGCA ACATTAACCG GAAGACCATC 
GGTGCCAAGC AGTTCCGAGG GCCCGACCCC GGTGTGCCCG CCTACCGTTT TGTCCGGTTT 
GACTACGTCC CCCCAGTGAA TACAGACGAC CTCAACAGGA TCGTTAAGCT TGCAAGGAGA 
AAGGAGGGCT TCTTCCTCAC AGCCCAGCTG AAGCAGGACC GCAAGTCTCG GGGAACACTC 
CTGGTGTTGG AAGGTCCCGG CACCTCCCAG AGGCAGTTTG AGATTGTGTC CAATGGCCCA 
GGGGATACCT TGGACCTCAA CTACTGGGTA GAAGGCCACC AGCATACCAA CTTCCTGGAG 
GATGTGGGTC TGGCTGACTC CCAGTGGAAG AATGTGACTG TGCAGGTGGC CAGTGACACC 
TATAGCCTGT ATGTGGGCTG TGATCTTATT GACAGTGTCA CCCTGGAAGA ACCCTTCTAT 
GAGCAGCTGG AAGCAGACAA GAGCAGGATG TACGTGGCCA AGGGTGCATC TCGAGAGAGT 
CACTTCAGGG GCTTGCTGCA GAATGTCCAT CTCGTGTTTG CAGATTCTGT GGAAGATATT 
CTAAGCAAGA AAGGCTGTCA ACACAGCCAG GGAGCTGAAG TCAACACCAT CAGTGAACAT 
ACAGAGACAC TCCACCTGAG CCCTCACATC ACCACAGATC TGGTGGTCCA GGGTGTGGAG 
AAGGCACAGG AGGTGTGTAC GCACTCCTGT GAAGAGCTGA GCAACATGAT GAACGAGCTG 
TCCGGATTGC ACGTCATGGT GAACCAGCTG AGCAAGAACC TGGAGAGAGT GTCTAGCGAT 
AACCAGTTCC TTTTGGAGCT CATTGGGGGC CCTCTGAAGA CAAGAAACAT GTCGGCCTGT 
GTGCAGGAGG GACGGATCTT TGCAGAAAAC GAAACCTGGG TTGTGGATAG TTGTACCACC 
TGCACCTGCA AGAAATTTAA AACAGTCTGC AATCAAATCA CCTGCTCACC TGCAACTTGT 
GCCAACCCAT CTTTGGTGGA AGGCGAGTGC TGTCCATCCT GTTCCCACTC TGCAGACAAC 
GATGAGGGCT GGTCTCCGTG GGCAGAGTGG ACCGAGTGTT CTGTCACCTG TGGCTCTGGG 
ACCCAGCAGA GAGGCCGGTC TTGTGATGTC ACCAGCAACA CCTGCCTGGG CCCCTCCATT 
CAGACAAGGA CATGCAGTTT GGGCAAATGT GATACGAGAA TCCGTCAGAA TGGAGGCTGG 
AGTCACTGGT CACCCTGGTC TTCGTGCTCC GTGACTTGTG GAGTTGGCAA TGTCACCCGC 
ATACGTCTCT GCAACTCACC AGTGCCCCAA ATGGGTGGCA AGAACTGCAA GGGCAGTGGC 
CGGGAAACCA AGGCCTGCCA GCGTGCTCCA TGCCCAATTG ATGGCCGCTG GAGCCCCTGG 
TCCCCTTGGT CAGCCTGCAC AGTTACCTGT GCTGGAGGGA TCCGTGAGCG CACACGTGTT 
TGCAACAGCC CTGAGCCCCA GTATGGAGGG AAGGATTGTG TCGGGGATGT GACAGAACAC 
CAAATGTGCA ACAAGAGGAG CTGCCCTATT GATGGATGCC TATCCAACCC GTGTTTCCCT 
GGAGCCAAGT GCAACAGCTT CCCCGATGGC TCCTGGTCCT GTGGTTCCTG CCCAGTGGGC 
TTTCTGGGCA ATGGCACCCA CTGTGAGGAC CTGGATGAGT GTGCTGTGGT CGCAGATATC 
TGCTTCTCAA TTAACAAAGC TTCCCGCTGT GTCAACACCA ACCCTGGCTT CCACTGCCTG 
CCTTGTCCGC CACGCTACAA GGGGACCCAA CCCTTCGGGA TTGGCCTGGA GGATGCTAAA 
ACAGAAAAAC AAGTATGTGA GCCAGAGAAT CCGTGCAAGG ACAAGACTCA CAACTGCCAC 
AAGCATGCAG AGTGCATCTA CCTGGGCCAC TTCAGTGACC CCATGTACAA GTGCGAGTGC 
CAGACTGGCT ATGCAGGTGA TGGGCTCATC TGCGGGGAGG ACTCAGACCT GGACGGTTGG 
CCCAACAGCA ACCTGGTGTG TGCTACCAAT GCCACCTACC ACTGCGTCAA GGACAACTGC 
CCCAAACTGC CAAATTCTGG GCAGGAGGAT TTTGATAAGG ACGGAATCGG AGATGCTTGC 
GACGAGGACG ATGATAACGA CGGCGTGAGC GATGAGAAGG ACAATTGCCC ACTTCTCTTC 
AATCCCCGCC AATTAGACTA TGATAAGGAT GAGGTTGGAG ACCGCTGTGA CAATTGCCCC 
TATGTGCACA ACCAAGCACA GATCGACACG GACAACAACG GTGAAGGGGA CGCCTGCTCT 
GTGGATATCG ACGGGGATGA TGTTTTCAAT GAGCGAGACA ATTGCCCGTA TGTCTACAAC 
ACTGACCAGA GAGACACAGA CGGTGACGGC GTTGGGGACC ACTGTGACAA CTGTCCTCTG 
ATGCATAACC CAGATCAGAT GGATCAGGAC AATGATCTCG TTGGAGACCA GTGTGATAAC 
AATGAGGACA TAGATGATGA CGGCCACCAG AACAACCAAG ACAACTGCCC ATACATCTCC 
AACTCCAACC AGGCTGACCA TGACAATGAC GGCAAGGGGG ATGCCTGTGA CTCCGATGAT 
GACAACGATG GTGTTCCAGA TGACAGGGAC AACTGCAGGC TTGTGTTCAA CCCCGACCAG 
GAAGACTCGG ATGGCGACGG CCGAGGTGAT ATTTGTAAAG ATGACTTTGA CAATGATAAT 
GTCCCAGATA TTGATGACGT GTGCCCCGAG AACAATGCCA TCACCGAGAC AGACTTCAGA 
AACTTTCAGA TGGTCCCTCT GGATCCCAAG GGGACCACAC AAATTGATCC CAACTGGGTA 
ATTCGTCACC AAGGCAAAGA GCTGGTGCAG ACAGCAAACT CGGACCCTGG CATCGCCGTA 
GGTTTCGATG AGTTTGGGTC TGTGGACTTC AGCGGCACTT TCTATGTCAA CACTGACCGG 
GACGATGACT ACGCCGGCTT CGTCTTTGGC TATCAGTCAA GCAGCCGCTT CTATGTGGTG 
ATGTGGAAGC AGGTGACCCA GACCTACTGG GAAGACAAGC CCAGTCGGGC TTACGGCTAC 
TCTGGTGTGT CACTCAAAGT AGTAAACTCC ACGACTGGTA CTGGCGAGCA CCTGAGGAAT 
GCCCTGTGGC ACACGGGAAA CACGGAAGGC CAGGTTCGAA CTCTATGGCA TGACCCCAAA 
AACATTGGCT GGAAGGACTA CACCGCCTAC AGGTGGCATC TGATTCACAG GCCTAAGACA 
GGCTACATGA GAGTCTTAGT GCATGAAGGA AAGCAGGTCA TGGCTGACTC AGGACCAATT 
TATGACCAAA CTTATGCTGG TGGACGGCTG GGTCTGTTTG TCTTCTCCCA AGAAATGGTC 
TACTTCTCAG ACCTCAAGTA TGAGTGCAGA GATGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Macroglia-derived thrombospondin 2 regulates alterations of presynaptic proteins of retinal neurons following elevated hydrostatic pressure.
PloS one12(9)e0185388(2017)
Wang S,Hu T,Wang Z,Li N,Zhou L,Liao L,Wang M,Liao L,Wang H,Zeng L,Fan C,Zhou H,Xiong K,Huang J,Chen D

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Cardiovascular research110(3)419-30(2016 06)
Barallobre-Barreiro J,Oklu R,Lynch M,Fava M,Baig F,Yin X,Barwari T,Potier DN,Albadawi H,Jahangiri M,Porter KE,Watkins MT,Misra S,Stoughton J,Mayr M

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Circulation research113(10)1138-47(2013 Oct)
Abonnenc M,Nabeebaccus AA,Mayr U,Barallobre-Barreiro J,Dong X,Cuello F,Sur S,Drozdov I,Langley SR,Lu R,Stathopoulou K,Didangelos A,Yin X,Zimmermann WH,Shah AM,Zampetaki A,Mayr M

Distribution of thrombospondins and their neuronal receptor ?2?1 in the rat retina.
Experimental eye research11136-49(2013 Jun)
Huang J,Zhou L,Wang H,Luo J,Zeng L,Xiong K,Chen D

Thrombin promotes the expression of thrombospondin-1 and -2 in a rat model of intracerebral hemorrhage.
Journal of the neurological sciences323(1-2)141-6(2012 Dec)
Yang AL,Zhou HJ,Lin Y,Luo JK,Cui HJ,Tang T,Yang QD

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Thbs2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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