Cidea cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cidea
Entrez Gene ID	291541
Full Name	cell death-inducing DFFA-like effector a
General protein information	Preferred Names cell death-inducing DFFA-like effector a Names cell death activator CIDE-A cell death-inducing DNA fragmentation factor, alpha subunit-like effector A
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 18 Map Location: 18q12.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001170467.1	NP_001163938.1	cell death activator CIDE-A

Pathways from BioSystems

Homologies

	CIDEA	XP_001094509.1
Gallus gallus (chicken)	CIDEA	NP_001182052.1
Pan troglodytes (chimpanzee)	CIDEA	XP_523993.2
Bos taurus (cattle)	CIDEA	NP_001076918.1
Mus musculus (house mouse)	Cidea	NP_031728.2
Rattus norvegicus (Norway rat)	Cidea	NP_001163938.1
Canis lupus familiaris (dog)	CIDEA	XP_547681.3
Danio rerio (zebrafish)	cidea	XP_003201313.1
Homo sapiens (human)	CIDEA	NP_001270.1
Xenopus tropicalis (tropical clawed frog)	cidea	NP_001007987.1

Gene Ontology
Bibliography

Related articles in PubMed

Acute cold exposure-induced down-regulation of CIDEA, cell death-inducing DNA fragmentation factor-alpha-like effector A, in rat interscapular brown adipose tissue by sympathetically activated beta3-adrenoreceptors.
Shimizu T, Yokotani K
Biochemical and biophysical research communications387(2)294-9(2009 Sep)

Cidea is associated with lipid droplets and insulin sensitivity in humans.
Puri V, Ranjit S, Konda S, Nicoloro SM, Straubhaar J, Chawla A, Chouinard M, Lin C, Burkart A, Corvera S, Perugini RA, Czech MP
Proceedings of the National Academy of Sciences of the United States of America105(22)7833-8(2008 Jun)

Glycoproteome profiling of transforming growth factor-beta (TGFbeta) signaling: nonglycosylated cell death-inducing DFF-like effector A inhibits TGFbeta1-dependent apoptosis.
Iwahana H, Yakymovych I, Dubrovska A, Hellman U, Souchelnytskyi S
Proteomics6(23)6168-80(2006 Dec)

Resveratrol improves health and survival of mice on a high-calorie diet.
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA
Nature444(7117)337-42(2006 Nov)

The CIDEA gene V115F polymorphism is associated with obesity in Swedish subjects.
Dahlman I, Kaaman M, Jiao H, Kere J, Laakso M, Arner P
Diabetes54(10)3032-4(2005 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggest that acute cold exposure resulted in down-regulation of CIDEA in interscapular brown adipose tissue by sympathetically activated beta(3)-adrenoreceptor-mediated mechanisms in rats.
Title: Acute cold exposure-induced down-regulation of CIDEA, cell death-inducing DNA fragmentation factor-alpha-like effector A, in rat interscapular brown adipose tissue by sympathetically activated beta3-adrenoreceptors.

The following Cidea gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cidea cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06247	NM_001170467.1 Latest version!	Rattus norvegicus cell death-inducing DFFA-like effector a (Cidea), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cidea ( NM_001170467.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001163938.1 Rattus norvegicus cell death-inducing DFFA-like effector a (Cidea), mRNA.

Price & Availability↑

CloneID	ORa06247
Clone ID Related Accession (Same CDS sequence)	NM_001170467.1
Accession Version	NM_001170467.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-28
Organism	Rattus norvegicus(Norway rat)
Product	cell death activator CIDE-A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FM041444.1, BF284899.1 and CR462136.1. On Dec 20, 2009 this sequence version replaced XM_214551.4. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGAGACCG CCAGGGACTA CGCGGGAGCC CTCATCAGGC CCCTGACATT CATGGGGTTG 
CAGACGAAAA AGGTCCTGCT TACCCCCCTC ATACACCCTG CTCGTCCTTT CCGGGTTTCA 
AACCATGACC GAAGCAGCCG GCGTGGGGTG ATGGCCAGCA GCCTGCGGGA ACTTATCAGC 
AAGACTCTGG ATGTCTTGGT CATCACAACT GGCCTGGTCA CGCTGGTGCT GGAGGAGGAT 
GGTACCGTGG TGGACACAGA GGAGTTCTTT CAGACCCTAA GAGACAACAC ACACTTCATG 
ATCTTGGAAA AGGGACAGAA ATGGACACCG GGCAATAAGT ATGTCTGCAC ACAAACAAAG 
AAGTCAGGAA TAGCCAGAGT CACCTTCGAC CTATACAGGC TGAATCCCAA GGACTTCCTC 
GGCTGTCTCA ATGTCAAAGC CACCATGTAT GAGATGTACT CAGTGTCGTA TGATATCCGC 
TGCACAAGCT TCAAGGCCTT GTTAAGGAGT CTGCTGCGGT TCGCATCCTA TGCTGCCCAG 
GTGACCGGAC AGTTCCTGGT TTATGCGGGC GCTTATGTGC TCCGAGCACT GGGTGACACA 
GAAGAGCAGC CATCCCCCAA GGCTAGCGCC AAAGGCTGGT TCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001163938.1
CDS	6..653
Translation	METARDYAGALIRPLTFMGLQTKKVLLTPLIHPARPFRVSNHDRSSRRGVMASSLRELISKTLDVLVITTGLVTLVLEEDGTVVDTEEFFQTLRDNTHFMILEKGQKWTPGNKYVCTQTKKSGIARVTFDLYRLNPKDFLGCLNVKATMYEMYSVSYDIRCTSFKALLRSLLRFASYAAQVTGQFLVYAGAYVLRALGDTEEQPSPKASAKGWFM

Target ORF information:

RefSeq Version	NM_001170467.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cell death-inducing DFFA-like effector a (Cidea), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001170467.1

ORF Insert Sequence:

ATGGAGACCG CCAGGGACTA CGCGGGAGCC CTCATCAGGC CCCTGACATT CATGGGGTTG 
CAGACGAAAA AGGTCCTGCT TACCCCCCTC ATACACCCTG CTCGTCCTTT CCGGGTTTCA 
AACCATGACC GAAGCAGCCG GCGTGGGGTG ATGGCCAGCA GCCTGCGGGA ACTTATCAGC 
AAGACTCTGG ATGTCTTGGT CATCACAACT GGCCTGGTCA CGCTGGTGCT GGAGGAGGAT 
GGTACCGTGG TGGACACAGA GGAGTTCTTT CAGACCCTAA GAGACAACAC ACACTTCATG 
ATCTTGGAAA AGGGACAGAA ATGGACACCG GGCAATAAGT ATGTCTGCAC ACAAACAAAG 
AAGTCAGGAA TAGCCAGAGT CACCTTCGAC CTATACAGGC TGAATCCCAA GGACTTCCTC 
GGCTGTCTCA ATGTCAAAGC CACCATGTAT GAGATGTACT CAGTGTCGTA TGATATCCGC 
TGCACAAGCT TCAAGGCCTT GTTAAGGAGT CTGCTGCGGT TCGCATCCTA TGCTGCCCAG 
GTGACCGGAC AGTTCCTGGT TTATGCGGGC GCTTATGTGC TCCGAGCACT GGGTGACACA 
GAAGAGCAGC CATCCCCCAA GGCTAGCGCC AAAGGCTGGT TCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Acute cold exposure-induced down-regulation of CIDEA, cell death-inducing DNA fragmentation factor-alpha-like effector A, in rat interscapular brown adipose tissue by sympathetically activated beta3-adrenoreceptors.
Biochemical and biophysical research communications387(2)294-9(2009 Sep)
Shimizu T,Yokotani K

Cidea is associated with lipid droplets and insulin sensitivity in humans.
Proceedings of the National Academy of Sciences of the United States of America105(22)7833-8(2008 Jun)
Puri V,Ranjit S,Konda S,Nicoloro SM,Straubhaar J,Chawla A,Chouinard M,Lin C,Burkart A,Corvera S,Perugini RA,Czech MP

Glycoproteome profiling of transforming growth factor-beta (TGFbeta) signaling: nonglycosylated cell death-inducing DFF-like effector A inhibits TGFbeta1-dependent apoptosis.
Proteomics6(23)6168-80(2006 Dec)
Iwahana H,Yakymovych I,Dubrovska A,Hellman U,Souchelnytskyi S

Resveratrol improves health and survival of mice on a high-calorie diet.
Nature444(7117)337-42(2006 Nov)
Baur JA,Pearson KJ,Price NL,Jamieson HA,Lerin C,Kalra A,Prabhu VV,Allard JS,Lopez-Lluch G,Lewis K,Pistell PJ,Poosala S,Becker KG,Boss O,Gwinn D,Wang M,Ramaswamy S,Fishbein KW,Spencer RG,Lakatta EG,Le Couteur D,Shaw RJ,Navas P,Puigserver P,Ingram DK,de Cabo R,Sinclair DA

The CIDEA gene V115F polymorphism is associated with obesity in Swedish subjects.
Diabetes54(10)3032-4(2005 Oct)
Dahlman I,Kaaman M,Jiao H,Kere J,Laakso M,Arner P

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Cidea cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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