Tnks cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tnks
Entrez Gene ID	290794
Full Name	tankyrase
General protein information	Preferred Names tankyrase Names tankyrase-1 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 16 Map Location: 16q12.2

mRNA and Protein(s)

mRNA	Protein	Name
NM_001106084.2	NP_001099554.2	tankyrase-1

Pathways from BioSystems

Homologies

Homo sapiens (human)	TNKS	NP_003738.2
Pan troglodytes (chimpanzee)	TNKS	XP_001137443.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001947	XP_321116.5
Bos taurus (cattle)	TNKS	NP_001193089.1
Gallus gallus (chicken)	TNKS	NP_989671.1
Drosophila melanogaster (fruit fly)	tankyrase	NP_001262963.1
Mus musculus (house mouse)	Tnks	NP_780300.2
Rattus norvegicus (Norway rat)	Tnks	NP_001099554.2
Danio rerio (zebrafish)	tnks	XP_687410.3
Canis lupus familiaris (dog)	TNKS	XP_849388.1
	TNKS	XP_001090358.1
Xenopus tropicalis (tropical clawed frog)	tnks	XP_002939302.1

Gene Ontology
Bibliography

Related articles in PubMed

Tankyrase inhibition regulates corpus luteum development and luteal function in gonadotropin-treated rats.
Accialini P, Irusta G, Bechis A, Bas D, Parborell F, Abramovich D, Tesone M
Molecular reproduction and development84(8)719-730(2017 Aug)

Loss of ATRX Suppresses Resolution of Telomere Cohesion to Control Recombination in ALT Cancer Cells.
Ramamoorthy M, Smith S
Cancer cell28(3)357-69(2015 Sep)

Disruption of Wnt/?-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.
Kulak O, Chen H, Holohan B, Wu X, He H, Borek D, Otwinowski Z, Yamaguchi K, Garofalo LA, Ma Z, Wright W, Chen C, Shay JW, Zhang X, Lum L
Molecular and cellular biology35(14)2425-35(2015 Jul)

Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation.
Barkauskaite E, Jankevicius G, Ahel I
Molecular cell58(6)935-46(2015 Jun)

Nutritional energy stimulates NAD+ production to promote tankyrase-mediated PARsylation in insulinoma cells.
Zhong L, Yeh TY, Hao J, Pourtabatabaei N, Mahata SK, Shao J, Chessler SD, Chi NW
PloS one10(4)e0122948(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

tankyrase-mediated PARsylation is promoted by nutritional energy stimulated NAD+ in insulinoma cells
Title: Nutritional energy stimulates NAD+ production to promote tankyrase-mediated PARsylation in insulinoma cells.

Tankyrase 1 and autophagy decrease in the corpus cavernosum smooth muscle cells from aging rats with erectile dysfunction, and tankyrase 1 may have a positive effect on proliferation by enhancing autophagy and regulating the mTOR signalling pathway.
Title: Effect of tankyrase 1 on autophagy in the corpus cavernosum smooth muscle cells from ageing rats with erectile dysfunction and its potential mechanism.

Increased STAT-1, IRF-1 and complement component C3 in several models of liver transplant tolerance suggests that the STAT-1/IRF-1 apoptotic pathway and C3 may be involved in the tolerogenic mechanism.
Title: Gene array analysis of a rat model of liver transplant tolerance identifies increased complement C3 and the STAT-1/IRF-1 pathway during tolerance induction.

The following Tnks gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tnks cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04443	NM_001106084.2 Latest version!	Rattus norvegicus tankyrase (Tnks), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$426.30 $609.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tnks ( NM_001106084.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099554.2 Rattus norvegicus tankyrase (Tnks), mRNA.

Price & Availability↑

CloneID	ORa04443
Clone ID Related Accession (Same CDS sequence)	NM_001106084.2
Accession Version	NM_001106084.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3954bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	tankyrase-1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07026046.1, AABR07026047.1 and AABR07026048.1. On Oct 27, 2010 this sequence version replaced NM_001106084.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCGT CGCGTCGCTC TCAGCATCAT CACCACCATC ATCAGCAACA GCTCCAGCCC 
GCCCCAGGGG CTTCGGCTCC GCCACCGCCA CCTCCCCCGC CGCTCAGCCC GGGCTTGGCC 
CCGGGACCTA CCCCGGCCTC TCCCACGGCC GGCGGCCTGG CGCCCTTCGC CTCCCCGCGG 
CACGGCCTGG CGCTGCCGGA GGGGGATGGC AGCCGGGACC CGCCCGACAG GCCGCGATCT 
CCGGACCCGG TGGACGGCGC GGTCTGCACG GTGGCTGCTA CGGCCGCGGC CCCGGCAGCT 
TCCGCCGCCG TCGGGGTCGC TCCCAGCCCA GCCGGCGGCG GCGGTAACAA CTCCGCGTCG 
TCCACTTCTT CGCCTACTTC TTCTTCGTCT TCCTCTCCGT CCTCCCCTGG CTCGAGCATA 
GCGGAGAGTC CCGAAGCCGC CGGAGTTGGC TCCACAGCAA CTTTGGGACC CGGGGCGGCG 
GGCCTTGGCC CGGGGGTCCC AGCCGTGAGT GGGGCCCTGC GGGAGCTGCT GGAGGCTTGT 
CGAAATGGGG ACGTGTCCCG GGTGAAGAGG TTGGTGGACG CAGCGAACGT GAATGCAAAG 
GACATGGCCG GCCGAAAGTC TTCTCCCCTG CACTTCGCAG CAGGTTTTGG AAGGAAGGAT 
GTTGTAGAAC ACTTGCTGCA GATGGGTGCC AATGTCCATG CCCGTGACGA TGGGGGTCTC 
ATCCCACTTC ATAACGCCTG TTCTTTTGGC CATGCGGAGG TTGTGAGTCT GTTACTGTGT 
CAAGGAGCAG ATCCGAATGC CAGAGATAAC TGGAACTATA CGCCTCTGCA TGAAGCTGCC 
ATTAAAGGGA AGATCGACGT TTGCATTGTG CTGCTGCAGC ACGGAGCTGA TCCAAACATC 
CGGAACACCG ATGGGAAATC GGCTCTGGAC CTGGCAGATC CTTCAGCAAA GGCTGTCCTC 
ACAGGTGAAT ACAAAAAGGA CGAACTCCTA GAAGCTGCTA GGAGTGGTAA TGAAGAAAAA 
CTAATGGCTT TACTGACTCC TCTAAATGTG AATTGCCATG CCAGTGATGG GCGAAAGTCT 
ACTCCGTTAC ACCTGGCCGC GGGCTACAAC AGAGTGCGGA TAGTTCAGCT GCTGCTACAG 
CACGGAGCTG ATGTCCACGC AAAAGACAAA GGCGGGCTTG TACCTCTTCA TAATGCATGC 
TCATACGGAC ACTATGAGGT CACAGAGCTG CTGTTAAAGC ATGGCGCTTG TGTCAACGCT 
ATGGATCTGT GGCAGTTCAC CCCGCTGCAT GAAGCCGCTT CCAAGAACCG CGTCGAAGTC 
TGTTCTTTGT TACTTAGTCA TGGTGCTGAT CCAACCTTGG TCAATTGCCA TGGCAAAAGT 
GCTGTGGATA TGGCTCCCAC TCCTGAGCTC CGGGAAAGAC TGACATATGA ATTTAAAGGC 
CATTCTTTAC TACAAGCTGC CAGAGAAGCA GACCTGGCCA AAGTGAAGAA AACACTTGCT 
TTGGAAATCA TTAACTTCAA GCAGCCACAG TCTCATGAAA CTGCCTTGCA TTGTGCTGTG 
GCCTCCTTGC ATCCCAAACG AAAGCAGGTG GCAGAACTGC TACTTAGGAA GGGCGCCAAT 
GTCAATGAAA AAAACAAGGA CTTCATGACT CCTTTGCATG TTGCAGCTGA AAGAGCTCAT 
AATGACGTCA TGGAGGTTCT GCATAAGCAT GGAGCAAAGA TGAACGCGCT GGACAGTCTA 
GGTCAGACTG CTTTGCACAG AGCTGCCTTG GCTGGCCACC TGCAGACCTG CCGCCTCCTG 
CTGAGTTACG GCTCTGACCC TTCCATCATC TCCCTGCAAG GCTTCACAGC CGCGCAGATG 
GGGAACGAAG CGGTGCAGCA GATTCTGAGC GAGAGTACTC CTATCCGCAC TTCTGATGTG 
GACTATCGAC TCTTAGAGGC ATCGAAAGCT GGTGACTTGG AAACTGTGAA GCAACTGTGC 
AGCCCGCAGA ATGTGAACTG CAGAGATCTG GAGGGCCGCC ATTCCACTCC CTTACACTTC 
GCTGCAGGCT ACAACCGTGT GTCTGTCGTC GAGTACCTTC TACATCATGG AGCTGATGTC 
CATGCCAAAG ACAAAGGGGG CTTGGTTCCC CTTCACAATG CCTGCTCCTA TGGACACTAC 
GAGGTAGCTG AGCTCTTGGT GAGGCACGGG GCTTCTGTCA ACGTGGCGGA CTTGTGGAAA 
TTTACCCCTC TCCATGAAGC CGCAGCCAAG GGAAAATATG AGATCTGCAA ACTCCTTCTA 
AAACATGGAG CAGATCCAAC TAAGAAGAAC AGAGATGGAA ACACACCCCT AGATCTGGTC 
AAAGAAGGAG ACACAGATAT TCAGGACCTA CTGAGGGGGG ATGCTGCCCT GTTGGATGCT 
GCCAAGAAGG GCTGCCTGGC CAGAGTGCAG AAGCTTTGTA CTCCAGAGAA CATCAACTGC 
CGAGACACCC AGGGCAGAAA CTCAACTCCT CTCCACCTGG CAGCGGGCTA TAATAACCTG 
GAAGTAGCCG AGTACCTGCT AGAGCGCGGC GCTGATGTGA ACGCCCAGGA CAAAGGAGGT 
TTAATTCCAC TCCACAACGC AGCGTCTTAT GGGCATGTTG ATATAGCAGC ATTACTGATA 
AAGTACAACA CGTGTGTAAA CGCAACGGAT AAGTGGGCCT TCACTCCCCT CCACGAAGCA 
GCCCAGAAGG GGAGGACACA GTTGTGTGCC CTACTCCTAG CACATGGCGC AGACCCAACC 
ATGAAGAACC AGGAGGGTCA GACACCTTTA GACCTGGCAA CGGCTGATGA CATCCGAGCT 
TTGCTGATAG ATGCCATGCC CCCTGAGGCC TTACCTACCT GTTTTAAACC TCAGGCAACT 
GTAGTTAGTG CCTCTCTGAT CTCACCAGCG TCCACCCCGT CCTGCCTCTC TGCTGCCAGC 
AGCATAGATA ACCTCACTGG CCCGTTAGCA GAGCTGGCTG TAGGAGGAGC CTCCAATGCG 
GGGGATGGTG CTGCGGGTGC AGAAAGGAAG GAAGGAGAAG TTGCGGGTCT TGACATGAAT 
ATCAGCCAAT TCCTTAAAAG CCTTGGCCTT GAGCACCTTC GGGACATCTT TGAAACAGAG 
CAGATCACGT TAGATGTGCT GGCCGATATG GGTCATGAGG AACTGAAAGA AATAGGCATC 
AATGCCTATG GACACCGCCA CAAGTTAATC AAGGGCGTTG AAAGACTCTT AGGTGGACAA 
CAAGGAACCA ATCCGTATCT GACCTTTCAC TGTGTGAATC AGGGAACTAT TTTACTAGAT 
CTTGCTCCAG AAGATAAAGA ATACCAATCA GTAGAAGAAG AGATGCAGAG TACTATTCGG 
GAGCACAGAG ATGGCGGGAA TGCTGGTGGC ATCTTCAACA GATACAATGT CATTCGAATT 
CAGAAAGTTG TAAACAAGAA GCTGAGGGAG CGGTTTTGTC ACAGACAAAA GGAGGTGTCT 
GAGGAGAACC ACAACCATCA CAATGAGCGC ATGCTGTTCC ACGGTTCCCC TTTCATTAAT 
GCCATTATTC ATAAAGGGTT TGATGAGCGG CACGCATACA TTGGAGGGAT GTTTGGAGCT 
GGGATTTACT TTGCCGAAAA CTCTTCCAAA AGCAATCAGT ATGTTTATGG AATTGGAGGA 
GGAACAGGCT GCCCCACACA CAAAGATAGG TCATGTTACG TATGTCACAG ACAAATGCTT 
TTCTGTAGAG TGACCCTTGG AAAGTCTTTT CTGCAATTCA GCACCATGAA AATGGCCCAT 
GCGCCTCCAG GACATCACTC AGTCATCGGT AGACCAAGTG TCAATGGGCT GGCGTATGCT 
GAATATGTCA TCTACAGAGG GGAACAGGCA TATCCAGAAT ATCTCATCAC CTACCAGATC 
ATGAAGCCGG AAGCCCCTTC CCAGACTGCA ACGGCAGCAG AGCAGAAGAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099554.2
CDS	26..3979
Translation	MAASRRSQHHHHHHQQQLQPAPGASAPPPPPPPPLSPGLAPGPTPASPTAGGLAPFASPRHGLALPEGDGSRDPPDRPRSPDPVDGAVCTVAATAAAPAASAAVGVAPSPAGGGGNNSASSTSSPTSSSSSSPSSPGSSIAESPEAAGVGSTATLGPGAAGLGPGVPAVSGALRELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSPQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLERGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPTCFKPQATVVSASLISPASTPSCLSAASSIDNLTGPLAELAVGGASNAGDGAAGAERKEGEVAGLDMNISQFLKSLGLEHLRDIFETEQITLDVLADMGHEELKEIGINAYGHRHKLIKGVERLLGGQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYVCHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTATAAEQKT

Target ORF information:

RefSeq Version	NM_001106084.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus tankyrase (Tnks), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106084.2

ORF Insert Sequence:

ATGGCGGCGT CGCGTCGCTC TCAGCATCAT CACCACCATC ATCAGCAACA GCTCCAGCCC 
GCCCCAGGGG CTTCGGCTCC GCCACCGCCA CCTCCCCCGC CGCTCAGCCC GGGCTTGGCC 
CCGGGACCTA CCCCGGCCTC TCCCACGGCC GGCGGCCTGG CGCCCTTCGC CTCCCCGCGG 
CACGGCCTGG CGCTGCCGGA GGGGGATGGC AGCCGGGACC CGCCCGACAG GCCGCGATCT 
CCGGACCCGG TGGACGGCGC GGTCTGCACG GTGGCTGCTA CGGCCGCGGC CCCGGCAGCT 
TCCGCCGCCG TCGGGGTCGC TCCCAGCCCA GCCGGCGGCG GCGGTAACAA CTCCGCGTCG 
TCCACTTCTT CGCCTACTTC TTCTTCGTCT TCCTCTCCGT CCTCCCCTGG CTCGAGCATA 
GCGGAGAGTC CCGAAGCCGC CGGAGTTGGC TCCACAGCAA CTTTGGGACC CGGGGCGGCG 
GGCCTTGGCC CGGGGGTCCC AGCCGTGAGT GGGGCCCTGC GGGAGCTGCT GGAGGCTTGT 
CGAAATGGGG ACGTGTCCCG GGTGAAGAGG TTGGTGGACG CAGCGAACGT GAATGCAAAG 
GACATGGCCG GCCGAAAGTC TTCTCCCCTG CACTTCGCAG CAGGTTTTGG AAGGAAGGAT 
GTTGTAGAAC ACTTGCTGCA GATGGGTGCC AATGTCCATG CCCGTGACGA TGGGGGTCTC 
ATCCCACTTC ATAACGCCTG TTCTTTTGGC CATGCGGAGG TTGTGAGTCT GTTACTGTGT 
CAAGGAGCAG ATCCGAATGC CAGAGATAAC TGGAACTATA CGCCTCTGCA TGAAGCTGCC 
ATTAAAGGGA AGATCGACGT TTGCATTGTG CTGCTGCAGC ACGGAGCTGA TCCAAACATC 
CGGAACACCG ATGGGAAATC GGCTCTGGAC CTGGCAGATC CTTCAGCAAA GGCTGTCCTC 
ACAGGTGAAT ACAAAAAGGA CGAACTCCTA GAAGCTGCTA GGAGTGGTAA TGAAGAAAAA 
CTAATGGCTT TACTGACTCC TCTAAATGTG AATTGCCATG CCAGTGATGG GCGAAAGTCT 
ACTCCGTTAC ACCTGGCCGC GGGCTACAAC AGAGTGCGGA TAGTTCAGCT GCTGCTACAG 
CACGGAGCTG ATGTCCACGC AAAAGACAAA GGCGGGCTTG TACCTCTTCA TAATGCATGC 
TCATACGGAC ACTATGAGGT CACAGAGCTG CTGTTAAAGC ATGGCGCTTG TGTCAACGCT 
ATGGATCTGT GGCAGTTCAC CCCGCTGCAT GAAGCCGCTT CCAAGAACCG CGTCGAAGTC 
TGTTCTTTGT TACTTAGTCA TGGTGCTGAT CCAACCTTGG TCAATTGCCA TGGCAAAAGT 
GCTGTGGATA TGGCTCCCAC TCCTGAGCTC CGGGAAAGAC TGACATATGA ATTTAAAGGC 
CATTCTTTAC TACAAGCTGC CAGAGAAGCA GACCTGGCCA AAGTGAAGAA AACACTTGCT 
TTGGAAATCA TTAACTTCAA GCAGCCACAG TCTCATGAAA CTGCCTTGCA TTGTGCTGTG 
GCCTCCTTGC ATCCCAAACG AAAGCAGGTG GCAGAACTGC TACTTAGGAA GGGCGCCAAT 
GTCAATGAAA AAAACAAGGA CTTCATGACT CCTTTGCATG TTGCAGCTGA AAGAGCTCAT 
AATGACGTCA TGGAGGTTCT GCATAAGCAT GGAGCAAAGA TGAACGCGCT GGACAGTCTA 
GGTCAGACTG CTTTGCACAG AGCTGCCTTG GCTGGCCACC TGCAGACCTG CCGCCTCCTG 
CTGAGTTACG GCTCTGACCC TTCCATCATC TCCCTGCAAG GCTTCACAGC CGCGCAGATG 
GGGAACGAAG CGGTGCAGCA GATTCTGAGC GAGAGTACTC CTATCCGCAC TTCTGATGTG 
GACTATCGAC TCTTAGAGGC ATCGAAAGCT GGTGACTTGG AAACTGTGAA GCAACTGTGC 
AGCCCGCAGA ATGTGAACTG CAGAGATCTG GAGGGCCGCC ATTCCACTCC CTTACACTTC 
GCTGCAGGCT ACAACCGTGT GTCTGTCGTC GAGTACCTTC TACATCATGG AGCTGATGTC 
CATGCCAAAG ACAAAGGGGG CTTGGTTCCC CTTCACAATG CCTGCTCCTA TGGACACTAC 
GAGGTAGCTG AGCTCTTGGT GAGGCACGGG GCTTCTGTCA ACGTGGCGGA CTTGTGGAAA 
TTTACCCCTC TCCATGAAGC CGCAGCCAAG GGAAAATATG AGATCTGCAA ACTCCTTCTA 
AAACATGGAG CAGATCCAAC TAAGAAGAAC AGAGATGGAA ACACACCCCT AGATCTGGTC 
AAAGAAGGAG ACACAGATAT TCAGGACCTA CTGAGGGGGG ATGCTGCCCT GTTGGATGCT 
GCCAAGAAGG GCTGCCTGGC CAGAGTGCAG AAGCTTTGTA CTCCAGAGAA CATCAACTGC 
CGAGACACCC AGGGCAGAAA CTCAACTCCT CTCCACCTGG CAGCGGGCTA TAATAACCTG 
GAAGTAGCCG AGTACCTGCT AGAGCGCGGC GCTGATGTGA ACGCCCAGGA CAAAGGAGGT 
TTAATTCCAC TCCACAACGC AGCGTCTTAT GGGCATGTTG ATATAGCAGC ATTACTGATA 
AAGTACAACA CGTGTGTAAA CGCAACGGAT AAGTGGGCCT TCACTCCCCT CCACGAAGCA 
GCCCAGAAGG GGAGGACACA GTTGTGTGCC CTACTCCTAG CACATGGCGC AGACCCAACC 
ATGAAGAACC AGGAGGGTCA GACACCTTTA GACCTGGCAA CGGCTGATGA CATCCGAGCT 
TTGCTGATAG ATGCCATGCC CCCTGAGGCC TTACCTACCT GTTTTAAACC TCAGGCAACT 
GTAGTTAGTG CCTCTCTGAT CTCACCAGCG TCCACCCCGT CCTGCCTCTC TGCTGCCAGC 
AGCATAGATA ACCTCACTGG CCCGTTAGCA GAGCTGGCTG TAGGAGGAGC CTCCAATGCG 
GGGGATGGTG CTGCGGGTGC AGAAAGGAAG GAAGGAGAAG TTGCGGGTCT TGACATGAAT 
ATCAGCCAAT TCCTTAAAAG CCTTGGCCTT GAGCACCTTC GGGACATCTT TGAAACAGAG 
CAGATCACGT TAGATGTGCT GGCCGATATG GGTCATGAGG AACTGAAAGA AATAGGCATC 
AATGCCTATG GACACCGCCA CAAGTTAATC AAGGGCGTTG AAAGACTCTT AGGTGGACAA 
CAAGGAACCA ATCCGTATCT GACCTTTCAC TGTGTGAATC AGGGAACTAT TTTACTAGAT 
CTTGCTCCAG AAGATAAAGA ATACCAATCA GTAGAAGAAG AGATGCAGAG TACTATTCGG 
GAGCACAGAG ATGGCGGGAA TGCTGGTGGC ATCTTCAACA GATACAATGT CATTCGAATT 
CAGAAAGTTG TAAACAAGAA GCTGAGGGAG CGGTTTTGTC ACAGACAAAA GGAGGTGTCT 
GAGGAGAACC ACAACCATCA CAATGAGCGC ATGCTGTTCC ACGGTTCCCC TTTCATTAAT 
GCCATTATTC ATAAAGGGTT TGATGAGCGG CACGCATACA TTGGAGGGAT GTTTGGAGCT 
GGGATTTACT TTGCCGAAAA CTCTTCCAAA AGCAATCAGT ATGTTTATGG AATTGGAGGA 
GGAACAGGCT GCCCCACACA CAAAGATAGG TCATGTTACG TATGTCACAG ACAAATGCTT 
TTCTGTAGAG TGACCCTTGG AAAGTCTTTT CTGCAATTCA GCACCATGAA AATGGCCCAT 
GCGCCTCCAG GACATCACTC AGTCATCGGT AGACCAAGTG TCAATGGGCT GGCGTATGCT 
GAATATGTCA TCTACAGAGG GGAACAGGCA TATCCAGAAT ATCTCATCAC CTACCAGATC 
ATGAAGCCGG AAGCCCCTTC CCAGACTGCA ACGGCAGCAG AGCAGAAGAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tankyrase inhibition regulates corpus luteum development and luteal function in gonadotropin-treated rats.
Molecular reproduction and development84(8)719-730(2017 Aug)
Accialini P,Irusta G,Bechis A,Bas D,Parborell F,Abramovich D,Tesone M

Loss of ATRX Suppresses Resolution of Telomere Cohesion to Control Recombination in ALT Cancer Cells.
Cancer cell28(3)357-69(2015 Sep)
Ramamoorthy M,Smith S

Disruption of Wnt/?-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.
Molecular and cellular biology35(14)2425-35(2015 Jul)
Kulak O,Chen H,Holohan B,Wu X,He H,Borek D,Otwinowski Z,Yamaguchi K,Garofalo LA,Ma Z,Wright W,Chen C,Shay JW,Zhang X,Lum L

Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation.
Molecular cell58(6)935-46(2015 Jun)
Barkauskaite E,Jankevicius G,Ahel I

Nutritional energy stimulates NAD+ production to promote tankyrase-mediated PARsylation in insulinoma cells.
PloS one10(4)e0122948(2015)
Zhong L,Yeh TY,Hao J,Pourtabatabaei N,Mahata SK,Shao J,Chessler SD,Chi NW

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Tnks cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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