Loxl2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Loxl2
Entrez Gene ID	290350
Full Name	lysyl oxidase-like 2
General protein information	Preferred Names lysyl oxidase-like 2 Names lysyl oxidase homolog 2 lysyl oxidase-like protein 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001106047.2	NP_001099517.2	lysyl oxidase homolog 2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	LOXL2	NP_002309.1
Rattus norvegicus (Norway rat)	Loxl2	NP_001099517.2
	LOXL2	XP_001105440.2
Gallus gallus (chicken)	LOXL2	XP_003642594.1
Xenopus tropicalis (tropical clawed frog)	loxl2	NP_001135520.1
Mus musculus (house mouse)	Loxl2	NP_201582.2
Danio rerio (zebrafish)	loxl2b	NP_001074095.1
Drosophila melanogaster (fruit fly)	lox2	NP_523806.2
Canis lupus familiaris (dog)	LOXL2	XP_543244.3
Bos taurus (cattle)	LOXL2	NP_001092523.1
Anopheles gambiae (African malaria mosquito)	SCRAL1	XP_312996.1

Gene Ontology
Bibliography

Related articles in PubMed

LOXL2 drives epithelial-mesenchymal transition via activation of IRE1-XBP1 signalling pathway.
Cuevas EP, Eraso P, Maz?n MJ, Santos V, Moreno-Bueno G, Cano A, Portillo F
Scientific reports744988(2017 Mar)

Lysyl oxidase-like 2 (LOXL2) oxidizes trimethylated lysine 4 in histone H3.
Herranz N, Dave N, Millanes-Romero A, Pascual-Reguant L, Morey L, D?az VM, L?renz-Fonfr?a V, Gutierrez-Gallego R, Jer?nimo C, Iturbide A, Di Croce L, Garc?a de Herreros A, Peir? S
The FEBS journal283(23)4263-4273(2016 12)

LOXL2 Oxidizes Methylated TAF10 and Controls TFIID-Dependent Genes during Neural Progenitor Differentiation.
Iturbide A, Pascual-Reguant L, Fargas L, Cebri? JP, Alsina B, Garc?a de Herreros A, Peir? S
Molecular cell58(5)755-66(2015 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Loxl2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Loxl2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42771	NM_001106047.2 Latest version!	Rattus norvegicus lysyl oxidase-like 2 (Loxl2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Loxl2 ( NM_001106047.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099517.2 Rattus norvegicus lysyl oxidase-like 2 (Loxl2), mRNA.

Price & Availability↑

CloneID	ORa42771
Clone ID Related Accession (Same CDS sequence)	NM_001106047.2
Accession Version	NM_001106047.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2331bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	lysyl oxidase homolog 2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC168900.1. On Sep 14, 2008 this sequence version replaced NM_001106047.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC168900.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689602 [ECO:0000348] ##Evidence-Data-END##

ATGGAGATCC CTTTTGGCTC CTGCCTCTAC AGCTGTTTGG CACTGCTTGT CTTGCTGCCC 
TCCCTGAGCC TAGCACAATA TGAGAGCTGG CCCTACCAGC TCCAATATCC CGAGTACTTC 
CAGCAGCCGC CTCCCGAGCA CCACCAGCAT CAGGTGCCCT CCGACGTGGT GAAGATCCAG 
GTCCGCCTGG CGGGCCAGAA GAGGAAACAT AATGAAGGCC GTGTGGAGGT CTATTACGAA 
GGCCAGTGGG GCACTGTGTG CGATGATGAT TTCTCTATCC ATGCTGCCCA TGTTGTCTGC 
CGGGAAGTGG GCTATGTGGA GGCCAAGTCC TGGACTGCCA GCTCCTCCTA CGGCCCAGGC 
GAAGGCCCCA TCTGGTTGGA CAACATCTAC TGCACAGGCA AAGAGTCAAC CCTGGCAGCT 
TGCTCCTCTA ATGGCTGGGG TGTCACTGAT TGCAAGCACA CTGAAGATGT TGGTGTGGTG 
TGCAGTGAAA AAAGAATTCC AGGCTTCAAA TTTGACAATT CATTGATCAA CCAAATAGAG 
AGCCTAAATA TACAGGTGGA AGACATCCGG ATTCGACCCA TCCTGTCTGC CTTCCGCCAT 
CGCAAGCCTG TGACAGAGGG CTACGTGGAG GTAAAGGAGG GCAAGGCCTG GAAGCAGATC 
TGTGACAAGC ACTGGACAGC CAAGAATTCC CACGTGGTCT GTGGCATGTT TGGCTTCCCA 
GCAGAGAAGA CTTACAACCC CAAAGCCTAC AAAACCTTTG CCTCAAGGAG GAAGCTGCGC 
TACTGGAAGT TTTCTATGAA CTGCACGGGA ACTGAAGCAC ACATCTCCAG CTGTAAGCTG 
GGCCCTCCCA TGTTCCGGGA CCCTGTGAAG AATGCCACCT GTGAGAACGG GCAGCCAGCT 
GTGGTCAGTT GTGTGCCTAG CCAGATCTTC AGCCCTGATG GACCCTCAAG GTTCCGGAAA 
GCCTATAAGC CGGAGCAACC CTTGGTGCGA CTGAGAGGTG GAGCCCAGGT CGGGGAGGGC 
CGCGTGGAGG TGCTCAAGAA TGGAGAATGG GGTACCGTCT GCGATGACAA GTGGGACCTG 
GTGTCTGCCA GCGTGGTCTG CAGGGAGCTG GGCTTCGGCA CAGCTAAAGA GGCTGTCACA 
GGCTCCAGGC TGGGGCAAGG GATTGGGCCC ATCCACCTCA ACGAGGTCCA GTGCACAGGG 
ACAGAGAAGT CCATCATAGA CTGCAAGCTC AACACAGAGT CGCAGGGCTG CAACCACGAG 
GAAGACGCCG GAGTGCGATG CAACATCCCC ATCATGGGCT TCCAGAAAAA GGTGCGCCTG 
AATGGAGGCC GCAATCCCTA TGAGGGTCGA GTGGAGGTAC TAACAGAGAG AAATGGGTCC 
CTCGTGTGGG GGAATGTATG TGGCCAGAAC TGGGGCATTG TGGAAGCCAT GGTGGTCTGC 
CGGCAGCTAG GATTGGGCTT TGCCAGCAAC GCCTTCCAGG AAACCTGGTA CTGGCATGGA 
AATATCTTCG CCAACAAAGT GATCATGAGT GGAGTGAAGT GCTCAGGAAC GGAGTTATCC 
CTGGCACACT GCCGCCATGA CGAGGAGGTG GTCTGCCCCG AGGGTGGGGT GCAGTATGGT 
GCTGGAGTCG CCTGCTCAGA AACTGCACCT GACCTGGTAC TTAACGCCGA GATTGTACAA 
CAGACCGCCT ATCTGGAGGA CAGGCCCATG GCCTTGCTGC AGTGTGCCAT GGAGGAAAAC 
TGCCTCTCAG CCTCCGCTGT GCACACCGAT CCCACCAGAG GCCACCGTCG CCTTCTACGC 
TTCTCTTCCC AGATCCACAA CAATGGCCAA TCTGACTTCC GCCCCAAGAA TGGCCGCCAT 
GCATGGATTT GGCATGACTG CCACAGGCAC TACCACAGCA TGGAAGTATT CACTTACTAT 
GACCTCCTGA GCCTCAACGG CACCAAGGTG GCTGAGGGCC ACAAGGCCAG CTTCTGCTTG 
GAGGACACTG AGTGTGAGGG AGACATTCAG AAGAGTTACG AGTGTGCCAA CTTCGGAGAA 
CAAGGCATCA CCATGGGCTG CTGGGACATG TATCGTCATG ACATTGACTG CCAGTGGATA 
GACATCACCG ATGTGCCCCC TGGAGACTAC CTGTTTCAGG TTGTCATTAA CCCCAACTAT 
GAGGTGCCAG AATCAGATTT CTCTAACAAC ATCATGAAGT GCAGGAGCCG CTATGATGGC 
TACCGCATCT GGATGTACAA TTGTCACGTA GGTGGAGCCT TCAGTGAGGA GACAGAACAG 
AAGTTCGAAC ACTTCAGTGG ACTCCTAAAT AATCAGCTCT CTGTGCAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099517.2
CDS	123..2453
Translation	MEIPFGSCLYSCLALLVLLPSLSLAQYESWPYQLQYPEYFQQPPPEHHQHQVPSDVVKIQVRLAGQKRKHNEGRVEVYYEGQWGTVCDDDFSIHAAHVVCREVGYVEAKSWTASSSYGPGEGPIWLDNIYCTGKESTLAACSSNGWGVTDCKHTEDVGVVCSEKRIPGFKFDNSLINQIESLNIQVEDIRIRPILSAFRHRKPVTEGYVEVKEGKAWKQICDKHWTAKNSHVVCGMFGFPAEKTYNPKAYKTFASRRKLRYWKFSMNCTGTEAHISSCKLGPPMFRDPVKNATCENGQPAVVSCVPSQIFSPDGPSRFRKAYKPEQPLVRLRGGAQVGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGTAKEAVTGSRLGQGIGPIHLNEVQCTGTEKSIIDCKLNTESQGCNHEEDAGVRCNIPIMGFQKKVRLNGGRNPYEGRVEVLTERNGSLVWGNVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGNIFANKVIMSGVKCSGTELSLAHCRHDEEVVCPEGGVQYGAGVACSETAPDLVLNAEIVQQTAYLEDRPMALLQCAMEENCLSASAVHTDPTRGHRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTYYDLLSLNGTKVAEGHKASFCLEDTECEGDIQKSYECANFGEQGITMGCWDMYRHDIDCQWIDITDVPPGDYLFQVVINPNYEVPESDFSNNIMKCRSRYDGYRIWMYNCHVGGAFSEETEQKFEHFSGLLNNQLSVQ

Target ORF information:

RefSeq Version	NM_001106047.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lysyl oxidase-like 2 (Loxl2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106047.2

ORF Insert Sequence:

ATGGAGATCC CTTTTGGCTC CTGCCTCTAC AGCTGTTTGG CACTGCTTGT CTTGCTGCCC 
TCCCTGAGCC TAGCACAATA TGAGAGCTGG CCCTACCAGC TCCAATATCC CGAGTACTTC 
CAGCAGCCGC CTCCCGAGCA CCACCAGCAT CAGGTGCCCT CCGACGTGGT GAAGATCCAG 
GTCCGCCTGG CGGGCCAGAA GAGGAAACAT AATGAAGGCC GTGTGGAGGT CTATTACGAA 
GGCCAGTGGG GCACTGTGTG CGATGATGAT TTCTCTATCC ATGCTGCCCA TGTTGTCTGC 
CGGGAAGTGG GCTATGTGGA GGCCAAGTCC TGGACTGCCA GCTCCTCCTA CGGCCCAGGC 
GAAGGCCCCA TCTGGTTGGA CAACATCTAC TGCACAGGCA AAGAGTCAAC CCTGGCAGCT 
TGCTCCTCTA ATGGCTGGGG TGTCACTGAT TGCAAGCACA CTGAAGATGT TGGTGTGGTG 
TGCAGTGAAA AAAGAATTCC AGGCTTCAAA TTTGACAATT CATTGATCAA CCAAATAGAG 
AGCCTAAATA TACAGGTGGA AGACATCCGG ATTCGACCCA TCCTGTCTGC CTTCCGCCAT 
CGCAAGCCTG TGACAGAGGG CTACGTGGAG GTAAAGGAGG GCAAGGCCTG GAAGCAGATC 
TGTGACAAGC ACTGGACAGC CAAGAATTCC CACGTGGTCT GTGGCATGTT TGGCTTCCCA 
GCAGAGAAGA CTTACAACCC CAAAGCCTAC AAAACCTTTG CCTCAAGGAG GAAGCTGCGC 
TACTGGAAGT TTTCTATGAA CTGCACGGGA ACTGAAGCAC ACATCTCCAG CTGTAAGCTG 
GGCCCTCCCA TGTTCCGGGA CCCTGTGAAG AATGCCACCT GTGAGAACGG GCAGCCAGCT 
GTGGTCAGTT GTGTGCCTAG CCAGATCTTC AGCCCTGATG GACCCTCAAG GTTCCGGAAA 
GCCTATAAGC CGGAGCAACC CTTGGTGCGA CTGAGAGGTG GAGCCCAGGT CGGGGAGGGC 
CGCGTGGAGG TGCTCAAGAA TGGAGAATGG GGTACCGTCT GCGATGACAA GTGGGACCTG 
GTGTCTGCCA GCGTGGTCTG CAGGGAGCTG GGCTTCGGCA CAGCTAAAGA GGCTGTCACA 
GGCTCCAGGC TGGGGCAAGG GATTGGGCCC ATCCACCTCA ACGAGGTCCA GTGCACAGGG 
ACAGAGAAGT CCATCATAGA CTGCAAGCTC AACACAGAGT CGCAGGGCTG CAACCACGAG 
GAAGACGCCG GAGTGCGATG CAACATCCCC ATCATGGGCT TCCAGAAAAA GGTGCGCCTG 
AATGGAGGCC GCAATCCCTA TGAGGGTCGA GTGGAGGTAC TAACAGAGAG AAATGGGTCC 
CTCGTGTGGG GGAATGTATG TGGCCAGAAC TGGGGCATTG TGGAAGCCAT GGTGGTCTGC 
CGGCAGCTAG GATTGGGCTT TGCCAGCAAC GCCTTCCAGG AAACCTGGTA CTGGCATGGA 
AATATCTTCG CCAACAAAGT GATCATGAGT GGAGTGAAGT GCTCAGGAAC GGAGTTATCC 
CTGGCACACT GCCGCCATGA CGAGGAGGTG GTCTGCCCCG AGGGTGGGGT GCAGTATGGT 
GCTGGAGTCG CCTGCTCAGA AACTGCACCT GACCTGGTAC TTAACGCCGA GATTGTACAA 
CAGACCGCCT ATCTGGAGGA CAGGCCCATG GCCTTGCTGC AGTGTGCCAT GGAGGAAAAC 
TGCCTCTCAG CCTCCGCTGT GCACACCGAT CCCACCAGAG GCCACCGTCG CCTTCTACGC 
TTCTCTTCCC AGATCCACAA CAATGGCCAA TCTGACTTCC GCCCCAAGAA TGGCCGCCAT 
GCATGGATTT GGCATGACTG CCACAGGCAC TACCACAGCA TGGAAGTATT CACTTACTAT 
GACCTCCTGA GCCTCAACGG CACCAAGGTG GCTGAGGGCC ACAAGGCCAG CTTCTGCTTG 
GAGGACACTG AGTGTGAGGG AGACATTCAG AAGAGTTACG AGTGTGCCAA CTTCGGAGAA 
CAAGGCATCA CCATGGGCTG CTGGGACATG TATCGTCATG ACATTGACTG CCAGTGGATA 
GACATCACCG ATGTGCCCCC TGGAGACTAC CTGTTTCAGG TTGTCATTAA CCCCAACTAT 
GAGGTGCCAG AATCAGATTT CTCTAACAAC ATCATGAAGT GCAGGAGCCG CTATGATGGC 
TACCGCATCT GGATGTACAA TTGTCACGTA GGTGGAGCCT TCAGTGAGGA GACAGAACAG 
AAGTTCGAAC ACTTCAGTGG ACTCCTAAAT AATCAGCTCT CTGTGCAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LOXL2 drives epithelial-mesenchymal transition via activation of IRE1-XBP1 signalling pathway.
Scientific reports744988(2017 Mar)
Cuevas EP,Eraso P,Maz?n MJ,Santos V,Moreno-Bueno G,Cano A,Portillo F

Lysyl oxidase-like 2 (LOXL2) oxidizes trimethylated lysine 4 in histone H3.
The FEBS journal283(23)4263-4273(2016 12)
Herranz N,Dave N,Millanes-Romero A,Pascual-Reguant L,Morey L,D?az VM,L?renz-Fonfr?a V,Gutierrez-Gallego R,Jer?nimo C,Iturbide A,Di Croce L,Garc?a de Herreros A,Peir? S

LOXL2 Oxidizes Methylated TAF10 and Controls TFIID-Dependent Genes during Neural Progenitor Differentiation.
Molecular cell58(5)755-66(2015 Jun)
Iturbide A,Pascual-Reguant L,Fargas L,Cebri? JP,Alsina B,Garc?a de Herreros A,Peir? S

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Loxl2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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