Plxna2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Plxna2
Entrez Gene ID	289392
Full Name	plexin A2
General protein information	Preferred Names plexin A2 Names plexin-A2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q27

mRNA and Protein(s)

mRNA	Protein	Name
NM_001105988.2	NP_001099458.2	plexin-A2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PLXNA2	XP_003308771.1
Rattus norvegicus (Norway rat)	Plxna2	NP_001099458.2
Danio rerio (zebrafish)	si:dkey-164k14.1	XP_689780.5
Drosophila melanogaster (fruit fly)	plexA	NP_524637.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000064	XP_311092.3
Homo sapiens (human)	PLXNA2	NP_079455.3
Canis lupus familiaris (dog)	PLXNA2	XP_547389.2
Bos taurus (cattle)	PLXNA2	NP_001193586.1
Mus musculus (house mouse)	Plxna2	NP_032908.2
Gallus gallus (chicken)	PLXNA2	XP_004935035.1
Caenorhabditis elegans (roundworm)	plx-1	NP_500018.3
Xenopus tropicalis (tropical clawed frog)	plxna2	NP_001116947.1
	PLXNA2	XP_001110951.2

Gene Ontology
Bibliography

Related articles in PubMed

Structural basis for semaphorin signalling through the plexin receptor.
Nogi T, Yasui N, Mihara E, Matsunaga Y, Noda M, Yamashita N, Toyofuku T, Uchiyama S, Goshima Y, Kumanogoh A, Takagi J
Nature467(7319)1123-7(2010 Oct)

Structural basis of semaphorin-plexin signalling.
Janssen BJ, Robinson RA, P?rez-Brangul? F, Bell CH, Mitchell KJ, Siebold C, Jones EY
Nature467(7319)1118-22(2010 Oct)

GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling.
Kodo K, Nishizawa T, Furutani M, Arai S, Yamamura E, Joo K, Takahashi T, Matsuoka R, Yamagishi H
Proceedings of the National Academy of Sciences of the United States of America106(33)13933-8(2009 Aug)

Plexin-A2 and its ligand, Sema6A, control nucleus-centrosome coupling in migrating granule cells.
Renaud J, Kerjan G, Sumita I, Zagar Y, Georget V, Kim D, Fouquet C, Suda K, Sanbo M, Suto F, Ackerman SL, Mitchell KJ, Fujisawa H, Ch?dotal A
Nature neuroscience11(4)440-9(2008 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Plxna2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Plxna2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10739	NM_001105988.2 Latest version!	Rattus norvegicus plexin A2 (Plxna2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$825.30 $1179.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Plxna2 ( NM_001105988.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099458.2 Rattus norvegicus plexin A2 (Plxna2), mRNA.

Price & Availability↑

CloneID	ORa10739
Clone ID Related Accession (Same CDS sequence)	NM_001105988.2
Accession Version	NM_001105988.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5685bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-28
Organism	Rattus norvegicus(Norway rat)
Product	plexin-A2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07022212.1, AABR07072360.1 and AC111280.7. On or before Oct 27, 2010 this sequence version replaced NM_001198564.1, NM_001105988.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCAGA GGAGGTTCCA GTTGCGGGCC ATGCAGGCTG ACAACCTGTC TGTGGTACTG 
CTCTCTGTGG CCTGGCTCCT GCTAGCCCGT GGGACCACAG GTATGCCTCA GTTCAGTACT 
TTCCACTCTG AGAATCGTGA CTGGACTTTT AACCATTTGA CTGTACACCG AAGAACAGGG 
GCTGTGTACG TGGGGGCCAT CAATCGTGTC TACAAGTTGA CTGGGAACCT CACCATCCAG 
GTGGCTCACA AGACGGGGCC AGAAGAGGAC AATAAGGCTT GCTACCCACC CCTCATTGTA 
CAGCCCTGTA GCGAAGTGCT CACACTTACC AATAATGTCA ACAAACTACT GATCATCGAC 
TACTCTGAGA ATCGCCTGCT TGCCTGTGGA AGCCTCTACC AGGGTGTTTG CAAGCTCCTG 
CGGCTAGATG ACCTCTTCAT CCTGGTGGAG CCATCCCACA AGAAGGAGCA CTACTTGTCC 
AGTGTCAATA AGACAGGAAC CATGTATGGT GTGATTGTGC GCTCTGAGGG GGAAGATGGC 
AAGCTTTTTA TCGGCACTGC TGTGGATGGC AAGCAGGATT ACTTCCCTAC CCTGTCCAGC 
CGCAAGCTGC CCCGTGACCC CGAGTCTTCG GCAATGCTGG ACTATGAGCT CCACAGTGAT 
TTTGTCTCTT CCCTCATCAA GATCCCCTCT GACACCCTAG CCCTGGTCTC CCACTTTGAC 
ATTTTCTACA TCTATGGCTT TGCCAGTGGA GGGTTTGTCT ACTTTCTCAC TGTCCAGCCA 
GAGACCCCAG AGGGCATGGC CATCAATTCA GCTGGAGACC TCTTCTATAC CTCGAGAATC 
GTGCGTCTCT GCAAGGATGA CCCCAAGTTC CATTCCTATG TGTCCCTGCC CTTTGGCTGC 
ACACGAGCTG GGGTGGAATA CCGCCTTCTG CAGGCAGCTT ACCTCGCAAA GCCAGGGGAA 
GCTCTAGCTC AGGCCTTCAA CATCAGCAGT GAAGAAGATG TGCTGTTTGC CATCTTCTCC 
AAGGGGCAGA AGCAGTACCA CCATCCCCCT GATGACTCTG CCCTATGTGC CTTCCCCATC 
CGGGCCATCA ACTTGCAAAT CAAGGAGCGG TTGCAGTCTT GCTACCATGG AGAGGGCAAC 
TTGGAGCTCA ACTGGCTGCT GGGAAAGGAT GTACAGTGCA CCAAGGCGCC AGTCCCCATC 
GATGATAACT TCTGTGGCTT GGACATCAAC CAGCCTCTGG GAGGCTCCAC TCCTGTGGAG 
GGACTGACCT TGTACACCAC CAGCAGGGAC CGCCTGACCT CTGTGGCCTC CTATGTTTAC 
AATGGCTACA GTGTGGTGTT TGTGGGGACT AAGAGTGGCA AGCTAAAGAA GATTCGAGCT 
GATGGTCCCC CCCATGGTGG GGTCCAATAT GAGATGGTCT CTGTGTTCAA AGATGGGAGC 
CCCATCCTCC GGGACATGGC CTTCTCCATC AATCAGCTGT ACCTATATGT CATGTCTGAG 
AGACAGGTCA CCAGGGTCCC TGTGGAATCA TGTGAACAAT ATACAACTTG TGGAGAGTGT 
CTAAGCTCAG GGGATCCTCA TTGTGGCTGG TGTGCCCTGC ACAACATGTG CTCTAGAAGA 
GACAAATGCC AACGGGCCTG GGAAGCAAAT CGATTCGCTG CCAGTATCAG CCAGTGTATG 
AGCCTTGAGG TGCACCCCAA CAGCATCTCT GTGTCAGATC ACAGCCGGCT GCTCAGCCTG 
GTTGTGAATG ATGCTCCCAA CCTCTCTGAG GGTATCGCCT GTGCCTTTGG GAACCTGACT 
GAGGTGGAGG GGCAGGTGTC TGGGAGTCAA GTCATATGCA TCTCACCTGG ACCCAAGGAT 
GTCCCTGTCA TTCCTCTGGA TCAAGACTGG TTTGGCCTGG AGCTGCAGCT GAGATCCAAA 
GAGACAGGAA AGATCTTTGT CAGCACCGAA TTCAAGTTCT ATAACTGCAG TGCCCACCAA 
CTGTGCCTGT CCTGTGTTAA CAGCGCCTTC CGCTGCCATT GGTGCAAGTA CCGGAACCTC 
TGTACACATG ATCCCACCAC CTGTTCCTTC CAGGAAGGCA GGATCAATGT TTCAGAGGAC 
TGTCCACAGC TCGTGCCCAC AGAAGAGATT CTGATCCCAG TTGGGGAAGT AAAACCAATC 
ACTCTTAAAG CCCGAAACCT GCCCCAACCC CAGTCTGGCC AGCGAGGCTA CGAATGTGTG 
CTCAACATTC AAGGGGCTGT CCACCGGGTC CCTGCCCTAC GTTTCAACAG TTCCAGTGTG 
CAGTGCCAAA ACAGCTCGTA CCAGTATGAC GGGATGGACA TCAGCAACCT AGCAGTGGAC 
TTTGCTGTGG TGTGGAATGG CAACTTCATT ATTGACAACC CTCAGGACCT GAAAGTACAC 
CTCTACAAGT GTGCAGCCCA GCGGGAAAGC TGTGGTCTCT GCCTCAAGGC TGATCACAAG 
TTCGAGTGTG GCTGGTGCAG TGGGGAGCGC AGATGTACCC TCCGCCAGCA TTGCCCCAGC 
ACTTCTAGCC CCTGGCTCGA CTGGTCCAGC CACAATGTCA AGTGCTCCAA CCCCCAAATC 
ACAGAGATTT TGACAGTATC AGGACCACCT GAAGGAGGGA CTCGTGTGAC CATCCATGGA 
GTGAACCTGG GCTTGGACTT CTCTGAGATC GCTCACCACG TGCAGGTGGC TGGAGTGCCC 
TGCACACCCA TCCCAGGGGA ATACATCATC GCTGAGCAGA TCGTCTGTGA GATGGGCCAT 
GCCCTTATGG GTACCACATC TGGGCCTGTG CGCCTGTGCA TTGGGGAATG CAAGCCAGAG 
TTCATGACCA AGTCCCACCA GCAGTATACA TTTGTGAATC CTTCTGTGCT GTCACTCAGC 
CCAATCCGGG GACCAGAGTC AGGAGGTACC ATGGTGACCA TCACAGGCCA TTACCTTGGT 
GCTGGGAGCA GCGTGGCAGT GTACCTGGGC AATCAGACCT GCGAATTCTA TGGGAGGTCA 
ATGAATGAGA TTGTCTGTGT TTCACCCCCA TCATCCAATG GACTAGGACC AGTCCCTGTC 
TCCGTGAGTG TCGACAGAGC CCGGGTAGAC AGCAGTCTAC AGTTCGAGTA CATAGATGAC 
CCACGGGTCC AACGTATTGA GCCAGAGTGG AGCATCACTA GTGGACACAC ACCCCTAACC 
ATCACAGGCT TCAACTTGGA TGTAATTCAG GAGCCAAGGA TCCGAGTCAA GTTCAATGGG 
AAAGAATCAG TCAATGTATG CACAGTGGTA AACACAACCA CCCTCACCTG TCTGGCACCC 
TCTCTGACCA GTGATTACCG TCCAGGTCTG GACACTGTGG AGCGGCCAGA TGAGTTTGGA 
TTTCTCTTTA ACAATGTCCA ATCCTTACTT ATCTATAATG ACACCAAGTT CATCTACTAC 
CCCAACCCAA CTTTTGAACT GCTCAGCCCC ACTGGAATCT TGGATCAGAA GCCAGGTTCA 
CCCATCATCC TGAAGGGCAA AAATCTCTGT CCTCCTGCCT CCGGAGGGGC CAAACTCAAC 
TACACAGTAA TGATTGGAGA GACACCTTGT ACAGTCACTG TGTCTGAGAC ACAACTGCTC 
TGTGAACCTC CCAACCTCAC AGGACAGCAC AAGGTCATGG TTCACGTGGG CGGGATGGTG 
TTCTCCCCTG GCTCTGTGAG TGTCATCTCC GACAGCTTGT TGACCCTGCC AGCCATCATC 
AGCATTGCAG CTGGTGGAAG CCTCCTTCTT ATCATCGTCA TCATTGTCCT CATCGCTTAC 
AAGCGCAAGT CTAGGGAAAA TGACCTCACA CTCAAACGGC TCCAAATGCA GATGGACAAC 
CTGGAGTCCA GGGTGGCGCT GGAATGCAAG GAAGCTTTTG CGGAGCTTCA GACAGACATC 
AATGAGCTAA CCAGTGACTT GGACCGATCA GGAATCCCTT ACCTGGACTA CCGTACCTAT 
GCCATGAGAG TACTGTTCCC AGGCATCGAG GACCACCCTG TTCTTCGGGA GCTGGAGGTA 
CAAGGAAATG GACAGCAGCA CGTGGAGAAA GCCCTGAAAC TCTTCGCCCA GCTTATCAAC 
AACAAGGTGT TCTTGCTGAC CTTCATCCGC ACACTGGAAC TACAGCGCAG CTTCTCCATG 
CGAGACCGTG GGAATGTGGC CTCTCTCATC ATGACAGGTC TTCAGGGTCG CCTGGAATAT 
GCCACCGATG TTCTCAAGCA GCTGCTCTCT GACCTCATTG ACAAGAACCT GGAGAACAAG 
AACCACCCCA AGCTGCTTCT CCGCAGGACT GAGTCTGTGG CGGAGAAGAT GCTGACCAAC 
TGGTTTGCTT TCCTTTTACA CAAGTTCCTA AAGGAGTGTG CTGGGGAACC ACTCTTCATG 
CTATACTGTG CAATCAAGCA GCAGATGGAG AAAGGCCCCA TTGATGCTAT CACTGGTGAG 
GCCCGGTACT CCCTGAGTGA AGACAAGCTC ATCCGGCAGC AGATCGAGTA CAAGACTCTG 
ATCCTGAACT GTGTCAACCC TGACAATGAG AATAGCCCAG AGATCCCCGT GAAGGTACTA 
AACTGTGACA CCATCACTCA AGTCAAGGAG AAGATCCTCG ATGCTGTATA TAAGAATGTT 
CCCTACTCCC AGCGGCCAAG GGCTGTGGAC ATGGACCTGG AGTGGCGCCA AGGCCGGATT 
GCCAGAGTGG TATTACAGGA TGAGGACATT ACCACCAAGA TAGAGGGTGA CTGGAAGCGG 
CTTAACACAC TGATGCATTA CCAGGTGTCA GACAGATCAG TGGTGGCTCT GGTCCCTAAG 
CAGACCTCCT CCTACAACAT CCCTGCCTCT GCCAGCATCT CTCGGACATC CATCAGCAGA 
TACGACTCTT CCTTCAGGTA CACAGGCAGC CCAGACAGCC TCCGGTCCCG GGTTCCCATG 
ATCACCCCAG ACCTGGAGAG TGGTGTCAAG GTTTGGCATC TGGTAAAGAA CCATGACCAT 
GGTGACCAGA AGGAGGGCGA CCGGGGCAGC AAAATGGTGT CTGAGATCTA CTTGACCCGG 
CTTCTAGCCA CCAAGGGCAC CCTGCAGAAA TTTGTGGACG ACTTGTTTGA GACCTTGTTC 
AGCACTGTGC ACAGGGGTAG TGCTCTCCCC CTAGCCATCA AGTACATGTT TGATTTCCTG 
GATGAGCAGG CAGACAGACA CAGTATCCAC GACACAGATG TGCGGCACAC CTGGAAAAGC 
AACTGCCTTC CACTTCGTTT CTGGGTGAAT GTCATCAAGA ACCCTCAATT TGTATTTGAC 
ATCCACAAGG GCAGCATCAC AGATGCTTGC CTCTCTGTGG TAGCCCAGAC CTTCATGGAC 
TCCTGCTCCA CATCAGAGCA CCGACTGGGC AAGGACTCAC CTTCCAATAA GTTGCTCTAT 
GCCAAGGATA TCCCCAGTTA CAAGAACTGG GTAGAAAGAT ACTATGCAGA TATTGCCAAG 
CTCCCAGCCA TTAGTGACCA AGATATGAAC GCCTACCTCG CGGAGCAGTC TCGCCTGCAT 
GCCACGGAGT TCAATATGCT GAGCGCCCTC AACGAGATCT ACTCCTATGT CAGCAAGTAC 
AGTGAGGAGC TCATCGGGGC ACTAGAGCAG GATGAGCAGG CCAGACGGCA ACGACTGGCC 
TACAAGGTGG AACATCTCAT CAATGCCATG TCCATAGAGA GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099458.2
CDS	646..6330
Translation	MEQRRFQLRAMQADNLSVVLLSVAWLLLARGTTGMPQFSTFHSENRDWTFNHLTVHRRTGAVYVGAINRVYKLTGNLTIQVAHKTGPEEDNKACYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLLRLDDLFILVEPSHKKEHYLSSVNKTGTMYGVIVRSEGEDGKLFIGTAVDGKQDYFPTLSSRKLPRDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPETPEGMAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLAKPGEALAQAFNISSEEDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYHGEGNLELNWLLGKDVQCTKAPVPIDDNFCGLDINQPLGGSTPVEGLTLYTTSRDRLTSVASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVFKDGSPILRDMAFSINQLYLYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSRRDKCQRAWEANRFAASISQCMSLEVHPNSISVSDHSRLLSLVVNDAPNLSEGIACAFGNLTEVEGQVSGSQVICISPGPKDVPVIPLDQDWFGLELQLRSKETGKIFVSTEFKFYNCSAHQLCLSCVNSAFRCHWCKYRNLCTHDPTTCSFQEGRINVSEDCPQLVPTEEILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAVHRVPALRFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRESCGLCLKADHKFECGWCSGERRCTLRQHCPSTSSPWLDWSSHNVKCSNPQITEILTVSGPPEGGTRVTIHGVNLGLDFSEIAHHVQVAGVPCTPIPGEYIIAEQIVCEMGHALMGTTSGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLSPIRGPESGGTMVTITGHYLGAGSSVAVYLGNQTCEFYGRSMNEIVCVSPPSSNGLGPVPVSVSVDRARVDSSLQFEYIDDPRVQRIEPEWSITSGHTPLTITGFNLDVIQEPRIRVKFNGKESVNVCTVVNTTTLTCLAPSLTSDYRPGLDTVERPDEFGFLFNNVQSLLIYNDTKFIYYPNPTFELLSPTGILDQKPGSPIILKGKNLCPPASGGAKLNYTVMIGETPCTVTVSETQLLCEPPNLTGQHKVMVHVGGMVFSPGSVSVISDSLLTLPAIISIAAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALECKEAFAELQTDINELTSDLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNGQQHVEKALKLFAQLINNKVFLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDVLKQLLSDLIDKNLENKNHPKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIEYKTLILNCVNPDNENSPEIPVKVLNCDTITQVKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWKRLNTLMHYQVSDRSVVALVPKQTSSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRVPMITPDLESGVKVWHLVKNHDHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETLFSTVHRGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKGSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYADIAKLPAISDQDMNAYLAEQSRLHATEFNMLSALNEIYSYVSKYSEELIGALEQDEQARRQRLAYKVEHLINAMSIES

Target ORF information:

RefSeq Version	NM_001105988.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus plexin A2 (Plxna2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001105988.2

ORF Insert Sequence:

ATGGAGCAGA GGAGGTTCCA GTTGCGGGCC ATGCAGGCTG ACAACCTGTC TGTGGTACTG 
CTCTCTGTGG CCTGGCTCCT GCTAGCCCGT GGGACCACAG GTATGCCTCA GTTCAGTACT 
TTCCACTCTG AGAATCGTGA CTGGACTTTT AACCATTTGA CTGTACACCG AAGAACAGGG 
GCTGTGTACG TGGGGGCCAT CAATCGTGTC TACAAGTTGA CTGGGAACCT CACCATCCAG 
GTGGCTCACA AGACGGGGCC AGAAGAGGAC AATAAGGCTT GCTACCCACC CCTCATTGTA 
CAGCCCTGTA GCGAAGTGCT CACACTTACC AATAATGTCA ACAAACTACT GATCATCGAC 
TACTCTGAGA ATCGCCTGCT TGCCTGTGGA AGCCTCTACC AGGGTGTTTG CAAGCTCCTG 
CGGCTAGATG ACCTCTTCAT CCTGGTGGAG CCATCCCACA AGAAGGAGCA CTACTTGTCC 
AGTGTCAATA AGACAGGAAC CATGTATGGT GTGATTGTGC GCTCTGAGGG GGAAGATGGC 
AAGCTTTTTA TCGGCACTGC TGTGGATGGC AAGCAGGATT ACTTCCCTAC CCTGTCCAGC 
CGCAAGCTGC CCCGTGACCC CGAGTCTTCG GCAATGCTGG ACTATGAGCT CCACAGTGAT 
TTTGTCTCTT CCCTCATCAA GATCCCCTCT GACACCCTAG CCCTGGTCTC CCACTTTGAC 
ATTTTCTACA TCTATGGCTT TGCCAGTGGA GGGTTTGTCT ACTTTCTCAC TGTCCAGCCA 
GAGACCCCAG AGGGCATGGC CATCAATTCA GCTGGAGACC TCTTCTATAC CTCGAGAATC 
GTGCGTCTCT GCAAGGATGA CCCCAAGTTC CATTCCTATG TGTCCCTGCC CTTTGGCTGC 
ACACGAGCTG GGGTGGAATA CCGCCTTCTG CAGGCAGCTT ACCTCGCAAA GCCAGGGGAA 
GCTCTAGCTC AGGCCTTCAA CATCAGCAGT GAAGAAGATG TGCTGTTTGC CATCTTCTCC 
AAGGGGCAGA AGCAGTACCA CCATCCCCCT GATGACTCTG CCCTATGTGC CTTCCCCATC 
CGGGCCATCA ACTTGCAAAT CAAGGAGCGG TTGCAGTCTT GCTACCATGG AGAGGGCAAC 
TTGGAGCTCA ACTGGCTGCT GGGAAAGGAT GTACAGTGCA CCAAGGCGCC AGTCCCCATC 
GATGATAACT TCTGTGGCTT GGACATCAAC CAGCCTCTGG GAGGCTCCAC TCCTGTGGAG 
GGACTGACCT TGTACACCAC CAGCAGGGAC CGCCTGACCT CTGTGGCCTC CTATGTTTAC 
AATGGCTACA GTGTGGTGTT TGTGGGGACT AAGAGTGGCA AGCTAAAGAA GATTCGAGCT 
GATGGTCCCC CCCATGGTGG GGTCCAATAT GAGATGGTCT CTGTGTTCAA AGATGGGAGC 
CCCATCCTCC GGGACATGGC CTTCTCCATC AATCAGCTGT ACCTATATGT CATGTCTGAG 
AGACAGGTCA CCAGGGTCCC TGTGGAATCA TGTGAACAAT ATACAACTTG TGGAGAGTGT 
CTAAGCTCAG GGGATCCTCA TTGTGGCTGG TGTGCCCTGC ACAACATGTG CTCTAGAAGA 
GACAAATGCC AACGGGCCTG GGAAGCAAAT CGATTCGCTG CCAGTATCAG CCAGTGTATG 
AGCCTTGAGG TGCACCCCAA CAGCATCTCT GTGTCAGATC ACAGCCGGCT GCTCAGCCTG 
GTTGTGAATG ATGCTCCCAA CCTCTCTGAG GGTATCGCCT GTGCCTTTGG GAACCTGACT 
GAGGTGGAGG GGCAGGTGTC TGGGAGTCAA GTCATATGCA TCTCACCTGG ACCCAAGGAT 
GTCCCTGTCA TTCCTCTGGA TCAAGACTGG TTTGGCCTGG AGCTGCAGCT GAGATCCAAA 
GAGACAGGAA AGATCTTTGT CAGCACCGAA TTCAAGTTCT ATAACTGCAG TGCCCACCAA 
CTGTGCCTGT CCTGTGTTAA CAGCGCCTTC CGCTGCCATT GGTGCAAGTA CCGGAACCTC 
TGTACACATG ATCCCACCAC CTGTTCCTTC CAGGAAGGCA GGATCAATGT TTCAGAGGAC 
TGTCCACAGC TCGTGCCCAC AGAAGAGATT CTGATCCCAG TTGGGGAAGT AAAACCAATC 
ACTCTTAAAG CCCGAAACCT GCCCCAACCC CAGTCTGGCC AGCGAGGCTA CGAATGTGTG 
CTCAACATTC AAGGGGCTGT CCACCGGGTC CCTGCCCTAC GTTTCAACAG TTCCAGTGTG 
CAGTGCCAAA ACAGCTCGTA CCAGTATGAC GGGATGGACA TCAGCAACCT AGCAGTGGAC 
TTTGCTGTGG TGTGGAATGG CAACTTCATT ATTGACAACC CTCAGGACCT GAAAGTACAC 
CTCTACAAGT GTGCAGCCCA GCGGGAAAGC TGTGGTCTCT GCCTCAAGGC TGATCACAAG 
TTCGAGTGTG GCTGGTGCAG TGGGGAGCGC AGATGTACCC TCCGCCAGCA TTGCCCCAGC 
ACTTCTAGCC CCTGGCTCGA CTGGTCCAGC CACAATGTCA AGTGCTCCAA CCCCCAAATC 
ACAGAGATTT TGACAGTATC AGGACCACCT GAAGGAGGGA CTCGTGTGAC CATCCATGGA 
GTGAACCTGG GCTTGGACTT CTCTGAGATC GCTCACCACG TGCAGGTGGC TGGAGTGCCC 
TGCACACCCA TCCCAGGGGA ATACATCATC GCTGAGCAGA TCGTCTGTGA GATGGGCCAT 
GCCCTTATGG GTACCACATC TGGGCCTGTG CGCCTGTGCA TTGGGGAATG CAAGCCAGAG 
TTCATGACCA AGTCCCACCA GCAGTATACA TTTGTGAATC CTTCTGTGCT GTCACTCAGC 
CCAATCCGGG GACCAGAGTC AGGAGGTACC ATGGTGACCA TCACAGGCCA TTACCTTGGT 
GCTGGGAGCA GCGTGGCAGT GTACCTGGGC AATCAGACCT GCGAATTCTA TGGGAGGTCA 
ATGAATGAGA TTGTCTGTGT TTCACCCCCA TCATCCAATG GACTAGGACC AGTCCCTGTC 
TCCGTGAGTG TCGACAGAGC CCGGGTAGAC AGCAGTCTAC AGTTCGAGTA CATAGATGAC 
CCACGGGTCC AACGTATTGA GCCAGAGTGG AGCATCACTA GTGGACACAC ACCCCTAACC 
ATCACAGGCT TCAACTTGGA TGTAATTCAG GAGCCAAGGA TCCGAGTCAA GTTCAATGGG 
AAAGAATCAG TCAATGTATG CACAGTGGTA AACACAACCA CCCTCACCTG TCTGGCACCC 
TCTCTGACCA GTGATTACCG TCCAGGTCTG GACACTGTGG AGCGGCCAGA TGAGTTTGGA 
TTTCTCTTTA ACAATGTCCA ATCCTTACTT ATCTATAATG ACACCAAGTT CATCTACTAC 
CCCAACCCAA CTTTTGAACT GCTCAGCCCC ACTGGAATCT TGGATCAGAA GCCAGGTTCA 
CCCATCATCC TGAAGGGCAA AAATCTCTGT CCTCCTGCCT CCGGAGGGGC CAAACTCAAC 
TACACAGTAA TGATTGGAGA GACACCTTGT ACAGTCACTG TGTCTGAGAC ACAACTGCTC 
TGTGAACCTC CCAACCTCAC AGGACAGCAC AAGGTCATGG TTCACGTGGG CGGGATGGTG 
TTCTCCCCTG GCTCTGTGAG TGTCATCTCC GACAGCTTGT TGACCCTGCC AGCCATCATC 
AGCATTGCAG CTGGTGGAAG CCTCCTTCTT ATCATCGTCA TCATTGTCCT CATCGCTTAC 
AAGCGCAAGT CTAGGGAAAA TGACCTCACA CTCAAACGGC TCCAAATGCA GATGGACAAC 
CTGGAGTCCA GGGTGGCGCT GGAATGCAAG GAAGCTTTTG CGGAGCTTCA GACAGACATC 
AATGAGCTAA CCAGTGACTT GGACCGATCA GGAATCCCTT ACCTGGACTA CCGTACCTAT 
GCCATGAGAG TACTGTTCCC AGGCATCGAG GACCACCCTG TTCTTCGGGA GCTGGAGGTA 
CAAGGAAATG GACAGCAGCA CGTGGAGAAA GCCCTGAAAC TCTTCGCCCA GCTTATCAAC 
AACAAGGTGT TCTTGCTGAC CTTCATCCGC ACACTGGAAC TACAGCGCAG CTTCTCCATG 
CGAGACCGTG GGAATGTGGC CTCTCTCATC ATGACAGGTC TTCAGGGTCG CCTGGAATAT 
GCCACCGATG TTCTCAAGCA GCTGCTCTCT GACCTCATTG ACAAGAACCT GGAGAACAAG 
AACCACCCCA AGCTGCTTCT CCGCAGGACT GAGTCTGTGG CGGAGAAGAT GCTGACCAAC 
TGGTTTGCTT TCCTTTTACA CAAGTTCCTA AAGGAGTGTG CTGGGGAACC ACTCTTCATG 
CTATACTGTG CAATCAAGCA GCAGATGGAG AAAGGCCCCA TTGATGCTAT CACTGGTGAG 
GCCCGGTACT CCCTGAGTGA AGACAAGCTC ATCCGGCAGC AGATCGAGTA CAAGACTCTG 
ATCCTGAACT GTGTCAACCC TGACAATGAG AATAGCCCAG AGATCCCCGT GAAGGTACTA 
AACTGTGACA CCATCACTCA AGTCAAGGAG AAGATCCTCG ATGCTGTATA TAAGAATGTT 
CCCTACTCCC AGCGGCCAAG GGCTGTGGAC ATGGACCTGG AGTGGCGCCA AGGCCGGATT 
GCCAGAGTGG TATTACAGGA TGAGGACATT ACCACCAAGA TAGAGGGTGA CTGGAAGCGG 
CTTAACACAC TGATGCATTA CCAGGTGTCA GACAGATCAG TGGTGGCTCT GGTCCCTAAG 
CAGACCTCCT CCTACAACAT CCCTGCCTCT GCCAGCATCT CTCGGACATC CATCAGCAGA 
TACGACTCTT CCTTCAGGTA CACAGGCAGC CCAGACAGCC TCCGGTCCCG GGTTCCCATG 
ATCACCCCAG ACCTGGAGAG TGGTGTCAAG GTTTGGCATC TGGTAAAGAA CCATGACCAT 
GGTGACCAGA AGGAGGGCGA CCGGGGCAGC AAAATGGTGT CTGAGATCTA CTTGACCCGG 
CTTCTAGCCA CCAAGGGCAC CCTGCAGAAA TTTGTGGACG ACTTGTTTGA GACCTTGTTC 
AGCACTGTGC ACAGGGGTAG TGCTCTCCCC CTAGCCATCA AGTACATGTT TGATTTCCTG 
GATGAGCAGG CAGACAGACA CAGTATCCAC GACACAGATG TGCGGCACAC CTGGAAAAGC 
AACTGCCTTC CACTTCGTTT CTGGGTGAAT GTCATCAAGA ACCCTCAATT TGTATTTGAC 
ATCCACAAGG GCAGCATCAC AGATGCTTGC CTCTCTGTGG TAGCCCAGAC CTTCATGGAC 
TCCTGCTCCA CATCAGAGCA CCGACTGGGC AAGGACTCAC CTTCCAATAA GTTGCTCTAT 
GCCAAGGATA TCCCCAGTTA CAAGAACTGG GTAGAAAGAT ACTATGCAGA TATTGCCAAG 
CTCCCAGCCA TTAGTGACCA AGATATGAAC GCCTACCTCG CGGAGCAGTC TCGCCTGCAT 
GCCACGGAGT TCAATATGCT GAGCGCCCTC AACGAGATCT ACTCCTATGT CAGCAAGTAC 
AGTGAGGAGC TCATCGGGGC ACTAGAGCAG GATGAGCAGG CCAGACGGCA ACGACTGGCC 
TACAAGGTGG AACATCTCAT CAATGCCATG TCCATAGAGA GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structural basis for semaphorin signalling through the plexin receptor.
Nature467(7319)1123-7(2010 Oct)
Nogi T,Yasui N,Mihara E,Matsunaga Y,Noda M,Yamashita N,Toyofuku T,Uchiyama S,Goshima Y,Kumanogoh A,Takagi J

Structural basis of semaphorin-plexin signalling.
Nature467(7319)1118-22(2010 Oct)
Janssen BJ,Robinson RA,P?rez-Brangul? F,Bell CH,Mitchell KJ,Siebold C,Jones EY

GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling.
Proceedings of the National Academy of Sciences of the United States of America106(33)13933-8(2009 Aug)
Kodo K,Nishizawa T,Furutani M,Arai S,Yamamura E,Joo K,Takahashi T,Matsuoka R,Yamagishi H

Plexin-A2 and its ligand, Sema6A, control nucleus-centrosome coupling in migrating granule cells.
Nature neuroscience11(4)440-9(2008 Apr)
Renaud J,Kerjan G,Sumita I,Zagar Y,Georget V,Kim D,Fouquet C,Suda K,Sanbo M,Suto F,Ackerman SL,Mitchell KJ,Fujisawa H,Ch?dotal A

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Plxna2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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