The following Spta1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Spta1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa01495 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001011908.3 | |
| Accession Version | NM_001011908.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 7251bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-09-30 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | spectrin alpha chain, erythrocytic 1 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY238342.1, EB480501.1, DY314141.1, CA504635.1 and AI639523.1. On Nov 26, 2008 this sequence version replaced NM_001011908.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN01906347, SAMN01906348 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGAAACTC CAAAGGAAAC TGCTGTTGAA AGCAGTGGAC CAAAGGTTCT AGAAACAGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001011908.2 |
| CDS | 181..7431 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001011908.3 |
1 | ATGGAAACTC CAAAGGAAAC TGCTGTTGAA AGCAGTGGAC CAAAGGTTCT AGAAACAGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The carboxyterminal EF domain of erythroid alpha-spectrin is necessary for optimal spectrin-actin binding. |
The small GTPase Rac1 regulates auditory hair cell morphogenesis. |
Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice. |
Different impacts of alleles alphaLEPRA and alphaLELY as assessed versus a novel, virtually null allele of the SPTA1 gene in trans. |
Murine recessive hereditary spherocytosis, sph/sph, is caused by a mutation in the erythroid alpha-spectrin gene. |
