Gene Symbol | Per1 |
Entrez Gene ID | 287422 |
Full Name | period circadian regulator 1 |
Synonyms | rper1 |
General protein information |
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Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome | |
Summary | This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by Clock/Arntl heterodimers but then represses this upregulation in a feedback loop using Per/Cry heterodimers to interact with Clock/Arntl. Polymorphisms in this gene may increase the risk of getting certain cancers. [provided by RefSeq, Jan 2014]. |