Mx2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mx2
Entrez Gene ID	286918
Full Name	MX dynamin like GTPase 2
Synonyms	Mx3
General protein information	Preferred Names MX dynamin like GTPase 2 Names interferon-induced GTP-binding protein Mx2 interferon-induced GTP-binding protein Mx3 myxovirus (influenza virus) resistance 2 myxovirus (influenza virus) resistance 3 myxovirus resistance protein 2 myxovirus resistance protein 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q12
Summary	involved in inhibiting vesicular stomatitis virus [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_134350.2	NP_599177.2	interferon-induced GTP-binding protein Mx2
XM_006248150.3	XP_006248212.1	interferon-induced GTP-binding protein Mx2 isoform X1
XM_008768568.2	XP_008766790.1	interferon-induced GTP-binding protein Mx2 isoform X1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	LOC100334797	XP_002660401.2
Homo sapiens (human)	MX1	NP_002453.2
Bos taurus (cattle)	MX1	NP_776365.1
Arabidopsis thaliana (thale cress)	DRP4C	NP_176252.1
Oryza sativa (rice)	Os03g0260000	NP_001049617.1
Oryza sativa (rice)	Os04g0129900	NP_001052093.2
	MX1	NP_001073161.1
Rattus norvegicus (Norway rat)	Mx2	NP_599177.2
Danio rerio (zebrafish)	mxb	NP_001122144.1
Xenopus tropicalis (tropical clawed frog)	mx2	XP_004912469.1
Pan troglodytes (chimpanzee)	MX1	XP_001171874.1
Canis lupus familiaris (dog)	MX1	NP_001003134.1
Danio rerio (zebrafish)	mxa	NP_891987.2

Gene Ontology
Bibliography

Related articles in PubMed

[Differentially expressed genes in the locus associated with relative kidney weight and resting blood pressure in hypertensive rats of the ISIAH strain].
Redina OE, Smolenskaya SE, Fedoseeva LA, Markel AL
Molekuliarnaia biologiia50(6)944-952(2016 Nov-Dec)

Transient dimerization of human MxA promotes GTP hydrolysis, resulting in a mechanical power stroke.
Rennie ML, McKelvie SA, Bulloch EM, Kingston RL
Structure (London, England : 1993)22(10)1433-45(2014 Oct)

In vitro inhibition of the replication of classical swine fever virus by porcine Mx1 protein.
He DN, Zhang XM, Liu K, Pang R, Zhao J, Zhou B, Chen PY
Antiviral research104128-35(2014 Apr)

Interferon-induced antiviral protein MxA interacts with the cellular RNA helicases UAP56 and URH49.
Wisskirchen C, Ludersdorfer TH, M?ller DA, Moritz E, Pavlovic J
The Journal of biological chemistry286(40)34743-51(2011 Oct)

A diverse range of gene products are effectors of the type I interferon antiviral response.
Schoggins JW, Wilson SJ, Panis M, Murphy MY, Jones CT, Bieniasz P, Rice CM
Nature472(7344)481-5(2011 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Six differentially expressed genes (Kcne1, Rcan1, Mx1, Mx2, Tmprss2, and RGD1559516) were identified in the renal cortex, and three genes (Rcan1, Mx2, and Tmprss2) were identified in the renal medulla.
Title: [Differentially expressed genes in the locus associated with relative kidney weight and resting blood pressure in hypertensive rats of the ISIAH strain].

The following Mx2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mx2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa01147	NM_134350.2 Latest version!	Rattus norvegicus MX dynamin like GTPase 2 (Mx2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa01147	XM_006248150.3 Latest version!	Rattus norvegicus myxovirus (influenza virus) resistance 2 (Mx2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa01147	XM_008768568.2 Latest version!	Rattus norvegicus myxovirus (influenza virus) resistance 2 (Mx2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mx2 ( NM_134350.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_599177.2 Rattus norvegicus MX dynamin like GTPase 2 (Mx2), mRNA.

Price & Availability↑

CloneID	ORa01147
Clone ID Related Accession (Same CDS sequence)	NM_134350.2 , XM_006248150.3 , XM_008768568.2
Accession Version	NM_134350.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1980bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	interferon-induced GTP-binding protein Mx2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC099808.1. On Jul 31, 2005 this sequence version replaced NM_134350.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC099808.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGTTCTTA GCACAGAGGA AAACAGGAGT GTTGATTTAG TCAACTTACC CAGTGTCCCA 
CTGCCCGATG GAGAGGCTGG CGTAGGGGAG AACAACAAGG ATTCCTTGAA CAACCTCTGC 
AGTCAGTATG AGGAGAAGGT GCGGCCCTGC ATTGACCTCA TCGACTCCCT GCGAGCTCTG 
GGTGTGGAGC AAGACCTGGC CCTGCCTGCC ATCGCTGTCA TCGGGGACCA GAGTTCAGGG 
AAGAGCTCTG TGCTGGAAGC ACTGTCTGGA GTGGCCCTCC CCAGAGGCAG TGGTATTGTC 
ACCAGATGTC CCCTGGTGCT GAAATTGAAG AAGCTGAATC AGGGAGAGGA GTGGAAAGGC 
AAAGTCACCT ATGATGACAT CGAAGTGGAG CTCTCTGATC CTTCAGAGGT GGAAGAGGCC 
ATCAACACAG GTCAGAACCA TATTGCTGGG GTAGGGCTGG GGATCAGTGA TAAACTCATT 
AGCCTGGATG TCAGCTCCCC ACACGTCCCA GACCTGACTC TGATTGACCT TCCTGGAATC 
ACCAGGGTGG CTGTAGGCAA CCAGCCTGCA GACATAGGAC GGCAGATCAA GAGACTTATC 
ACTAACTACA TCCAAAAACA AGAGACCATC AACCTGGTGG TGGTCCCCAG CAATGTGGAC 
ATTGCCACCA CAGAGGCCCT GAGCATGGCT CAGAAGGTGG ACCCTGATGG GGATAGGACC 
ATAGGGATCT TGACCAAGCC TGATCTGGTG GACAGAGGGA CTGAAGACAA GGTCGTGGAT 
GTGGTGAGGA ACCTCGTGTG CCACCTGAAG AAGGGCTACA TGATAGTCAA GTGCAGGGGT 
CAGCAGGACA TCCAGGAGCA GCTGAGCCTG GCTGAGGCTC TTCAGAAGGA GCAAGTCTTC 
TTCAAGGAAC ACCCTCAATT CAGAGCTCTT CTGGAGGATG GGAAGGCCAC AGTGCCCTGC 
CTGGCAGAGA GGCTGACCAT GGAGCTCATC TCACACATCT GTAAATCTCT TCCTTTGTTA 
GAAAATCAAA TAAAGGAAAG TCACCAGAGT ACAAGTGAGG AGCTGCAGAA GTATGGTGCA 
GACATACCAG AAGATGAGAA TGAAAAAACT CTCTTCCTGA TTGAAAAAAT CAATGCTTTT 
AACCAGGACA TCACTGCCAT AGTAGAAGGG GAAGAGATTG TGAGGGAGAA AGAATGTCGC 
CTATTCACCA AGCTCCGTAA AGAGTTCTTC TTGTGGAGTG AGGAGATCGA AAGGAATTTC 
CAAAAAGGTT CTGATGCTTT ATATAAAGAA GTCTACACAT TCGAAATGCA GTATCGTGGC 
CGAGAACTAC CAGGGTTTGT GAATTACAAA ACATTTGAGA ACATCATAAG AAGACAAATC 
AAAACCCTGG AAGAACCAGC TATGGAAATG CTTCACAAGG TCACTGAAAT TGTACGGGCT 
GCCTTTACAA CGGTTTCTGA GAAAAATTTC TCTGAGTTTT TTAATCTCCA CAGAACTACC 
AAGTCCAAAC TTGAAGACAT CAGATTAGAA CAGGAAACGG AAGCAGAGAA GGCGATCCGG 
CTTCACTTCC AGATGGAACA AATCATCTAC TGCCAGGACC AAATTTATAG GAAAGCCTTG 
CAGAAGGTGA GAGAGGAGGA AGCTGAGGAG GAGGAGAGGA AGCATGGCAA AAGCAGGTCC 
GCTCAGTCCC CAAATTTACA GACCTCATCC ATGGATGAAA TCTTCCAGCA TCTGAATGCC 
TACCGCCAGG AGGCTCACAA CTGCATCTCC AGCCACATTC CATTGATCAT CCAGTATTTC 
ATCTTGAAGA TGTTTGCTGA GAAGCTGCAG AAGGGCATGC TCCAGCTCCT GCAGGACAAG 
GATTCCTGCA GCTGGCTCCT GAAGGAAAAG AGTGACACCA GTGAGAAGAG GAGATTCCTG 
AAGGAGCGGT TGGCAAGGCT GGCCCAAGCT CAGCGCAGGC TAGCCAAATT CCCTGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_599177.2
CDS	122..2101
Translation	MVLSTEENRSVDLVNLPSVPLPDGEAGVGENNKDSLNNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLNQGEEWKGKVTYDDIEVELSDPSEVEEAINTGQNHIAGVGLGISDKLISLDVSSPHVPDLTLIDLPGITRVAVGNQPADIGRQIKRLITNYIQKQETINLVVVPSNVDIATTEALSMAQKVDPDGDRTIGILTKPDLVDRGTEDKVVDVVRNLVCHLKKGYMIVKCRGQQDIQEQLSLAEALQKEQVFFKEHPQFRALLEDGKATVPCLAERLTMELISHICKSLPLLENQIKESHQSTSEELQKYGADIPEDENEKTLFLIEKINAFNQDITAIVEGEEIVREKECRLFTKLRKEFFLWSEEIERNFQKGSDALYKEVYTFEMQYRGRELPGFVNYKTFENIIRRQIKTLEEPAMEMLHKVTEIVRAAFTTVSEKNFSEFFNLHRTTKSKLEDIRLEQETEAEKAIRLHFQMEQIIYCQDQIYRKALQKVREEEAEEEERKHGKSRSAQSPNLQTSSMDEIFQHLNAYRQEAHNCISSHIPLIIQYFILKMFAEKLQKGMLQLLQDKDSCSWLLKEKSDTSEKRRFLKERLARLAQAQRRLAKFPG

Target ORF information:

RefSeq Version	NM_134350.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus MX dynamin like GTPase 2 (Mx2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_134350.2

ORF Insert Sequence:

ATGGTTCTTA GCACAGAGGA AAACAGGAGT GTTGATTTAG TCAACTTACC CAGTGTCCCA 
CTGCCCGATG GAGAGGCTGG CGTAGGGGAG AACAACAAGG ATTCCTTGAA CAACCTCTGC 
AGTCAGTATG AGGAGAAGGT GCGGCCCTGC ATTGACCTCA TCGACTCCCT GCGAGCTCTG 
GGTGTGGAGC AAGACCTGGC CCTGCCTGCC ATCGCTGTCA TCGGGGACCA GAGTTCAGGG 
AAGAGCTCTG TGCTGGAAGC ACTGTCTGGA GTGGCCCTCC CCAGAGGCAG TGGTATTGTC 
ACCAGATGTC CCCTGGTGCT GAAATTGAAG AAGCTGAATC AGGGAGAGGA GTGGAAAGGC 
AAAGTCACCT ATGATGACAT CGAAGTGGAG CTCTCTGATC CTTCAGAGGT GGAAGAGGCC 
ATCAACACAG GTCAGAACCA TATTGCTGGG GTAGGGCTGG GGATCAGTGA TAAACTCATT 
AGCCTGGATG TCAGCTCCCC ACACGTCCCA GACCTGACTC TGATTGACCT TCCTGGAATC 
ACCAGGGTGG CTGTAGGCAA CCAGCCTGCA GACATAGGAC GGCAGATCAA GAGACTTATC 
ACTAACTACA TCCAAAAACA AGAGACCATC AACCTGGTGG TGGTCCCCAG CAATGTGGAC 
ATTGCCACCA CAGAGGCCCT GAGCATGGCT CAGAAGGTGG ACCCTGATGG GGATAGGACC 
ATAGGGATCT TGACCAAGCC TGATCTGGTG GACAGAGGGA CTGAAGACAA GGTCGTGGAT 
GTGGTGAGGA ACCTCGTGTG CCACCTGAAG AAGGGCTACA TGATAGTCAA GTGCAGGGGT 
CAGCAGGACA TCCAGGAGCA GCTGAGCCTG GCTGAGGCTC TTCAGAAGGA GCAAGTCTTC 
TTCAAGGAAC ACCCTCAATT CAGAGCTCTT CTGGAGGATG GGAAGGCCAC AGTGCCCTGC 
CTGGCAGAGA GGCTGACCAT GGAGCTCATC TCACACATCT GTAAATCTCT TCCTTTGTTA 
GAAAATCAAA TAAAGGAAAG TCACCAGAGT ACAAGTGAGG AGCTGCAGAA GTATGGTGCA 
GACATACCAG AAGATGAGAA TGAAAAAACT CTCTTCCTGA TTGAAAAAAT CAATGCTTTT 
AACCAGGACA TCACTGCCAT AGTAGAAGGG GAAGAGATTG TGAGGGAGAA AGAATGTCGC 
CTATTCACCA AGCTCCGTAA AGAGTTCTTC TTGTGGAGTG AGGAGATCGA AAGGAATTTC 
CAAAAAGGTT CTGATGCTTT ATATAAAGAA GTCTACACAT TCGAAATGCA GTATCGTGGC 
CGAGAACTAC CAGGGTTTGT GAATTACAAA ACATTTGAGA ACATCATAAG AAGACAAATC 
AAAACCCTGG AAGAACCAGC TATGGAAATG CTTCACAAGG TCACTGAAAT TGTACGGGCT 
GCCTTTACAA CGGTTTCTGA GAAAAATTTC TCTGAGTTTT TTAATCTCCA CAGAACTACC 
AAGTCCAAAC TTGAAGACAT CAGATTAGAA CAGGAAACGG AAGCAGAGAA GGCGATCCGG 
CTTCACTTCC AGATGGAACA AATCATCTAC TGCCAGGACC AAATTTATAG GAAAGCCTTG 
CAGAAGGTGA GAGAGGAGGA AGCTGAGGAG GAGGAGAGGA AGCATGGCAA AAGCAGGTCC 
GCTCAGTCCC CAAATTTACA GACCTCATCC ATGGATGAAA TCTTCCAGCA TCTGAATGCC 
TACCGCCAGG AGGCTCACAA CTGCATCTCC AGCCACATTC CATTGATCAT CCAGTATTTC 
ATCTTGAAGA TGTTTGCTGA GAAGCTGCAG AAGGGCATGC TCCAGCTCCT GCAGGACAAG 
GATTCCTGCA GCTGGCTCCT GAAGGAAAAG AGTGACACCA GTGAGAAGAG GAGATTCCTG 
AAGGAGCGGT TGGCAAGGCT GGCCCAAGCT CAGCGCAGGC TAGCCAAATT CCCTGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mx2 ( XM_006248150.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006248212.1 Rattus norvegicus myxovirus (influenza virus) resistance 2 (Mx2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa01147
Clone ID Related Accession (Same CDS sequence)	NM_134350.2 , XM_006248150.3 , XM_008768568.2
Accession Version	XM_006248150.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1980bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	interferon-induced GTP-binding protein Mx2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006248150.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTTCTTA GCACAGAGGA AAACAGGAGT GTTGATTTAG TCAACTTACC CAGTGTCCCA 
CTGCCCGATG GAGAGGCTGG CGTAGGGGAG AACAACAAGG ATTCCTTGAA CAACCTCTGC 
AGTCAGTATG AGGAGAAGGT GCGGCCCTGC ATTGACCTCA TCGACTCCCT GCGAGCTCTG 
GGTGTGGAGC AAGACCTGGC CCTGCCTGCC ATCGCTGTCA TCGGGGACCA GAGTTCAGGG 
AAGAGCTCTG TGCTGGAAGC ACTGTCTGGA GTGGCCCTCC CCAGAGGCAG TGGTATTGTC 
ACCAGATGTC CCCTGGTGCT GAAATTGAAG AAGCTGAATC AGGGAGAGGA GTGGAAAGGC 
AAAGTCACCT ATGATGACAT CGAAGTGGAG CTCTCTGATC CTTCAGAGGT GGAAGAGGCC 
ATCAACACAG GTCAGAACCA TATTGCTGGG GTAGGGCTGG GGATCAGTGA TAAACTCATT 
AGCCTGGATG TCAGCTCCCC ACACGTCCCA GACCTGACTC TGATTGACCT TCCTGGAATC 
ACCAGGGTGG CTGTAGGCAA CCAGCCTGCA GACATAGGAC GGCAGATCAA GAGACTTATC 
ACTAACTACA TCCAAAAACA AGAGACCATC AACCTGGTGG TGGTCCCCAG CAATGTGGAC 
ATTGCCACCA CAGAGGCCCT GAGCATGGCT CAGAAGGTGG ACCCTGATGG GGATAGGACC 
ATAGGGATCT TGACCAAGCC TGATCTGGTG GACAGAGGGA CTGAAGACAA GGTCGTGGAT 
GTGGTGAGGA ACCTCGTGTG CCACCTGAAG AAGGGCTACA TGATAGTCAA GTGCAGGGGT 
CAGCAGGACA TCCAGGAGCA GCTGAGCCTG GCTGAGGCTC TTCAGAAGGA GCAAGTCTTC 
TTCAAGGAAC ACCCTCAATT CAGAGCTCTT CTGGAGGATG GGAAGGCCAC AGTGCCCTGC 
CTGGCAGAGA GGCTGACCAT GGAGCTCATC TCACACATCT GTAAATCTCT TCCTTTGTTA 
GAAAATCAAA TAAAGGAAAG TCACCAGAGT ACAAGTGAGG AGCTGCAGAA GTATGGTGCA 
GACATACCAG AAGATGAGAA TGAAAAAACT CTCTTCCTGA TTGAAAAAAT CAATGCTTTT 
AACCAGGACA TCACTGCCAT AGTAGAAGGG GAAGAGATTG TGAGGGAGAA AGAATGTCGC 
CTATTCACCA AGCTCCGTAA AGAGTTCTTC TTGTGGAGTG AGGAGATCGA AAGGAATTTC 
CAAAAAGGTT CTGATGCTTT ATATAAAGAA GTCTACACAT TCGAAATGCA GTATCGTGGC 
CGAGAACTAC CAGGGTTTGT GAATTACAAA ACATTTGAGA ACATCATAAG AAGACAAATC 
AAAACCCTGG AAGAACCAGC TATGGAAATG CTTCACAAGG TCACTGAAAT TGTACGGGCT 
GCCTTTACAA CGGTTTCTGA GAAAAATTTC TCTGAGTTTT TTAATCTCCA CAGAACTACC 
AAGTCCAAAC TTGAAGACAT CAGATTAGAA CAGGAAACGG AAGCAGAGAA GGCGATCCGG 
CTTCACTTCC AGATGGAACA AATCATCTAC TGCCAGGACC AAATTTATAG GAAAGCCTTG 
CAGAAGGTGA GAGAGGAGGA AGCTGAGGAG GAGGAGAGGA AGCATGGCAA AAGCAGGTCC 
GCTCAGTCCC CAAATTTACA GACCTCATCC ATGGATGAAA TCTTCCAGCA TCTGAATGCC 
TACCGCCAGG AGGCTCACAA CTGCATCTCC AGCCACATTC CATTGATCAT CCAGTATTTC 
ATCTTGAAGA TGTTTGCTGA GAAGCTGCAG AAGGGCATGC TCCAGCTCCT GCAGGACAAG 
GATTCCTGCA GCTGGCTCCT GAAGGAAAAG AGTGACACCA GTGAGAAGAG GAGATTCCTG 
AAGGAGCGGT TGGCAAGGCT GGCCCAAGCT CAGCGCAGGC TAGCCAAATT CCCTGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006248212.1
CDS	268..2247
Translation	MVLSTEENRSVDLVNLPSVPLPDGEAGVGENNKDSLNNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLNQGEEWKGKVTYDDIEVELSDPSEVEEAINTGQNHIAGVGLGISDKLISLDVSSPHVPDLTLIDLPGITRVAVGNQPADIGRQIKRLITNYIQKQETINLVVVPSNVDIATTEALSMAQKVDPDGDRTIGILTKPDLVDRGTEDKVVDVVRNLVCHLKKGYMIVKCRGQQDIQEQLSLAEALQKEQVFFKEHPQFRALLEDGKATVPCLAERLTMELISHICKSLPLLENQIKESHQSTSEELQKYGADIPEDENEKTLFLIEKINAFNQDITAIVEGEEIVREKECRLFTKLRKEFFLWSEEIERNFQKGSDALYKEVYTFEMQYRGRELPGFVNYKTFENIIRRQIKTLEEPAMEMLHKVTEIVRAAFTTVSEKNFSEFFNLHRTTKSKLEDIRLEQETEAEKAIRLHFQMEQIIYCQDQIYRKALQKVREEEAEEEERKHGKSRSAQSPNLQTSSMDEIFQHLNAYRQEAHNCISSHIPLIIQYFILKMFAEKLQKGMLQLLQDKDSCSWLLKEKSDTSEKRRFLKERLARLAQAQRRLAKFPG

Target ORF information:

RefSeq Version	XM_006248150.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus myxovirus (influenza virus) resistance 2 (Mx2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006248150.3

ORF Insert Sequence:

ATGGTTCTTA GCACAGAGGA AAACAGGAGT GTTGATTTAG TCAACTTACC CAGTGTCCCA 
CTGCCCGATG GAGAGGCTGG CGTAGGGGAG AACAACAAGG ATTCCTTGAA CAACCTCTGC 
AGTCAGTATG AGGAGAAGGT GCGGCCCTGC ATTGACCTCA TCGACTCCCT GCGAGCTCTG 
GGTGTGGAGC AAGACCTGGC CCTGCCTGCC ATCGCTGTCA TCGGGGACCA GAGTTCAGGG 
AAGAGCTCTG TGCTGGAAGC ACTGTCTGGA GTGGCCCTCC CCAGAGGCAG TGGTATTGTC 
ACCAGATGTC CCCTGGTGCT GAAATTGAAG AAGCTGAATC AGGGAGAGGA GTGGAAAGGC 
AAAGTCACCT ATGATGACAT CGAAGTGGAG CTCTCTGATC CTTCAGAGGT GGAAGAGGCC 
ATCAACACAG GTCAGAACCA TATTGCTGGG GTAGGGCTGG GGATCAGTGA TAAACTCATT 
AGCCTGGATG TCAGCTCCCC ACACGTCCCA GACCTGACTC TGATTGACCT TCCTGGAATC 
ACCAGGGTGG CTGTAGGCAA CCAGCCTGCA GACATAGGAC GGCAGATCAA GAGACTTATC 
ACTAACTACA TCCAAAAACA AGAGACCATC AACCTGGTGG TGGTCCCCAG CAATGTGGAC 
ATTGCCACCA CAGAGGCCCT GAGCATGGCT CAGAAGGTGG ACCCTGATGG GGATAGGACC 
ATAGGGATCT TGACCAAGCC TGATCTGGTG GACAGAGGGA CTGAAGACAA GGTCGTGGAT 
GTGGTGAGGA ACCTCGTGTG CCACCTGAAG AAGGGCTACA TGATAGTCAA GTGCAGGGGT 
CAGCAGGACA TCCAGGAGCA GCTGAGCCTG GCTGAGGCTC TTCAGAAGGA GCAAGTCTTC 
TTCAAGGAAC ACCCTCAATT CAGAGCTCTT CTGGAGGATG GGAAGGCCAC AGTGCCCTGC 
CTGGCAGAGA GGCTGACCAT GGAGCTCATC TCACACATCT GTAAATCTCT TCCTTTGTTA 
GAAAATCAAA TAAAGGAAAG TCACCAGAGT ACAAGTGAGG AGCTGCAGAA GTATGGTGCA 
GACATACCAG AAGATGAGAA TGAAAAAACT CTCTTCCTGA TTGAAAAAAT CAATGCTTTT 
AACCAGGACA TCACTGCCAT AGTAGAAGGG GAAGAGATTG TGAGGGAGAA AGAATGTCGC 
CTATTCACCA AGCTCCGTAA AGAGTTCTTC TTGTGGAGTG AGGAGATCGA AAGGAATTTC 
CAAAAAGGTT CTGATGCTTT ATATAAAGAA GTCTACACAT TCGAAATGCA GTATCGTGGC 
CGAGAACTAC CAGGGTTTGT GAATTACAAA ACATTTGAGA ACATCATAAG AAGACAAATC 
AAAACCCTGG AAGAACCAGC TATGGAAATG CTTCACAAGG TCACTGAAAT TGTACGGGCT 
GCCTTTACAA CGGTTTCTGA GAAAAATTTC TCTGAGTTTT TTAATCTCCA CAGAACTACC 
AAGTCCAAAC TTGAAGACAT CAGATTAGAA CAGGAAACGG AAGCAGAGAA GGCGATCCGG 
CTTCACTTCC AGATGGAACA AATCATCTAC TGCCAGGACC AAATTTATAG GAAAGCCTTG 
CAGAAGGTGA GAGAGGAGGA AGCTGAGGAG GAGGAGAGGA AGCATGGCAA AAGCAGGTCC 
GCTCAGTCCC CAAATTTACA GACCTCATCC ATGGATGAAA TCTTCCAGCA TCTGAATGCC 
TACCGCCAGG AGGCTCACAA CTGCATCTCC AGCCACATTC CATTGATCAT CCAGTATTTC 
ATCTTGAAGA TGTTTGCTGA GAAGCTGCAG AAGGGCATGC TCCAGCTCCT GCAGGACAAG 
GATTCCTGCA GCTGGCTCCT GAAGGAAAAG AGTGACACCA GTGAGAAGAG GAGATTCCTG 
AAGGAGCGGT TGGCAAGGCT GGCCCAAGCT CAGCGCAGGC TAGCCAAATT CCCTGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mx2 ( XM_008768568.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008766790.1 Rattus norvegicus myxovirus (influenza virus) resistance 2 (Mx2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa01147
Clone ID Related Accession (Same CDS sequence)	NM_134350.2 , XM_006248150.3 , XM_008768568.2
Accession Version	XM_008768568.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1980bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	interferon-induced GTP-binding protein Mx2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008768568.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTTCTTA GCACAGAGGA AAACAGGAGT GTTGATTTAG TCAACTTACC CAGTGTCCCA 
CTGCCCGATG GAGAGGCTGG CGTAGGGGAG AACAACAAGG ATTCCTTGAA CAACCTCTGC 
AGTCAGTATG AGGAGAAGGT GCGGCCCTGC ATTGACCTCA TCGACTCCCT GCGAGCTCTG 
GGTGTGGAGC AAGACCTGGC CCTGCCTGCC ATCGCTGTCA TCGGGGACCA GAGTTCAGGG 
AAGAGCTCTG TGCTGGAAGC ACTGTCTGGA GTGGCCCTCC CCAGAGGCAG TGGTATTGTC 
ACCAGATGTC CCCTGGTGCT GAAATTGAAG AAGCTGAATC AGGGAGAGGA GTGGAAAGGC 
AAAGTCACCT ATGATGACAT CGAAGTGGAG CTCTCTGATC CTTCAGAGGT GGAAGAGGCC 
ATCAACACAG GTCAGAACCA TATTGCTGGG GTAGGGCTGG GGATCAGTGA TAAACTCATT 
AGCCTGGATG TCAGCTCCCC ACACGTCCCA GACCTGACTC TGATTGACCT TCCTGGAATC 
ACCAGGGTGG CTGTAGGCAA CCAGCCTGCA GACATAGGAC GGCAGATCAA GAGACTTATC 
ACTAACTACA TCCAAAAACA AGAGACCATC AACCTGGTGG TGGTCCCCAG CAATGTGGAC 
ATTGCCACCA CAGAGGCCCT GAGCATGGCT CAGAAGGTGG ACCCTGATGG GGATAGGACC 
ATAGGGATCT TGACCAAGCC TGATCTGGTG GACAGAGGGA CTGAAGACAA GGTCGTGGAT 
GTGGTGAGGA ACCTCGTGTG CCACCTGAAG AAGGGCTACA TGATAGTCAA GTGCAGGGGT 
CAGCAGGACA TCCAGGAGCA GCTGAGCCTG GCTGAGGCTC TTCAGAAGGA GCAAGTCTTC 
TTCAAGGAAC ACCCTCAATT CAGAGCTCTT CTGGAGGATG GGAAGGCCAC AGTGCCCTGC 
CTGGCAGAGA GGCTGACCAT GGAGCTCATC TCACACATCT GTAAATCTCT TCCTTTGTTA 
GAAAATCAAA TAAAGGAAAG TCACCAGAGT ACAAGTGAGG AGCTGCAGAA GTATGGTGCA 
GACATACCAG AAGATGAGAA TGAAAAAACT CTCTTCCTGA TTGAAAAAAT CAATGCTTTT 
AACCAGGACA TCACTGCCAT AGTAGAAGGG GAAGAGATTG TGAGGGAGAA AGAATGTCGC 
CTATTCACCA AGCTCCGTAA AGAGTTCTTC TTGTGGAGTG AGGAGATCGA AAGGAATTTC 
CAAAAAGGTT CTGATGCTTT ATATAAAGAA GTCTACACAT TCGAAATGCA GTATCGTGGC 
CGAGAACTAC CAGGGTTTGT GAATTACAAA ACATTTGAGA ACATCATAAG AAGACAAATC 
AAAACCCTGG AAGAACCAGC TATGGAAATG CTTCACAAGG TCACTGAAAT TGTACGGGCT 
GCCTTTACAA CGGTTTCTGA GAAAAATTTC TCTGAGTTTT TTAATCTCCA CAGAACTACC 
AAGTCCAAAC TTGAAGACAT CAGATTAGAA CAGGAAACGG AAGCAGAGAA GGCGATCCGG 
CTTCACTTCC AGATGGAACA AATCATCTAC TGCCAGGACC AAATTTATAG GAAAGCCTTG 
CAGAAGGTGA GAGAGGAGGA AGCTGAGGAG GAGGAGAGGA AGCATGGCAA AAGCAGGTCC 
GCTCAGTCCC CAAATTTACA GACCTCATCC ATGGATGAAA TCTTCCAGCA TCTGAATGCC 
TACCGCCAGG AGGCTCACAA CTGCATCTCC AGCCACATTC CATTGATCAT CCAGTATTTC 
ATCTTGAAGA TGTTTGCTGA GAAGCTGCAG AAGGGCATGC TCCAGCTCCT GCAGGACAAG 
GATTCCTGCA GCTGGCTCCT GAAGGAAAAG AGTGACACCA GTGAGAAGAG GAGATTCCTG 
AAGGAGCGGT TGGCAAGGCT GGCCCAAGCT CAGCGCAGGC TAGCCAAATT CCCTGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008766790.1
CDS	202..2181
Translation	MVLSTEENRSVDLVNLPSVPLPDGEAGVGENNKDSLNNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLNQGEEWKGKVTYDDIEVELSDPSEVEEAINTGQNHIAGVGLGISDKLISLDVSSPHVPDLTLIDLPGITRVAVGNQPADIGRQIKRLITNYIQKQETINLVVVPSNVDIATTEALSMAQKVDPDGDRTIGILTKPDLVDRGTEDKVVDVVRNLVCHLKKGYMIVKCRGQQDIQEQLSLAEALQKEQVFFKEHPQFRALLEDGKATVPCLAERLTMELISHICKSLPLLENQIKESHQSTSEELQKYGADIPEDENEKTLFLIEKINAFNQDITAIVEGEEIVREKECRLFTKLRKEFFLWSEEIERNFQKGSDALYKEVYTFEMQYRGRELPGFVNYKTFENIIRRQIKTLEEPAMEMLHKVTEIVRAAFTTVSEKNFSEFFNLHRTTKSKLEDIRLEQETEAEKAIRLHFQMEQIIYCQDQIYRKALQKVREEEAEEEERKHGKSRSAQSPNLQTSSMDEIFQHLNAYRQEAHNCISSHIPLIIQYFILKMFAEKLQKGMLQLLQDKDSCSWLLKEKSDTSEKRRFLKERLARLAQAQRRLAKFPG

Target ORF information:

RefSeq Version	XM_008768568.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus myxovirus (influenza virus) resistance 2 (Mx2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008768568.2

ORF Insert Sequence:

ATGGTTCTTA GCACAGAGGA AAACAGGAGT GTTGATTTAG TCAACTTACC CAGTGTCCCA 
CTGCCCGATG GAGAGGCTGG CGTAGGGGAG AACAACAAGG ATTCCTTGAA CAACCTCTGC 
AGTCAGTATG AGGAGAAGGT GCGGCCCTGC ATTGACCTCA TCGACTCCCT GCGAGCTCTG 
GGTGTGGAGC AAGACCTGGC CCTGCCTGCC ATCGCTGTCA TCGGGGACCA GAGTTCAGGG 
AAGAGCTCTG TGCTGGAAGC ACTGTCTGGA GTGGCCCTCC CCAGAGGCAG TGGTATTGTC 
ACCAGATGTC CCCTGGTGCT GAAATTGAAG AAGCTGAATC AGGGAGAGGA GTGGAAAGGC 
AAAGTCACCT ATGATGACAT CGAAGTGGAG CTCTCTGATC CTTCAGAGGT GGAAGAGGCC 
ATCAACACAG GTCAGAACCA TATTGCTGGG GTAGGGCTGG GGATCAGTGA TAAACTCATT 
AGCCTGGATG TCAGCTCCCC ACACGTCCCA GACCTGACTC TGATTGACCT TCCTGGAATC 
ACCAGGGTGG CTGTAGGCAA CCAGCCTGCA GACATAGGAC GGCAGATCAA GAGACTTATC 
ACTAACTACA TCCAAAAACA AGAGACCATC AACCTGGTGG TGGTCCCCAG CAATGTGGAC 
ATTGCCACCA CAGAGGCCCT GAGCATGGCT CAGAAGGTGG ACCCTGATGG GGATAGGACC 
ATAGGGATCT TGACCAAGCC TGATCTGGTG GACAGAGGGA CTGAAGACAA GGTCGTGGAT 
GTGGTGAGGA ACCTCGTGTG CCACCTGAAG AAGGGCTACA TGATAGTCAA GTGCAGGGGT 
CAGCAGGACA TCCAGGAGCA GCTGAGCCTG GCTGAGGCTC TTCAGAAGGA GCAAGTCTTC 
TTCAAGGAAC ACCCTCAATT CAGAGCTCTT CTGGAGGATG GGAAGGCCAC AGTGCCCTGC 
CTGGCAGAGA GGCTGACCAT GGAGCTCATC TCACACATCT GTAAATCTCT TCCTTTGTTA 
GAAAATCAAA TAAAGGAAAG TCACCAGAGT ACAAGTGAGG AGCTGCAGAA GTATGGTGCA 
GACATACCAG AAGATGAGAA TGAAAAAACT CTCTTCCTGA TTGAAAAAAT CAATGCTTTT 
AACCAGGACA TCACTGCCAT AGTAGAAGGG GAAGAGATTG TGAGGGAGAA AGAATGTCGC 
CTATTCACCA AGCTCCGTAA AGAGTTCTTC TTGTGGAGTG AGGAGATCGA AAGGAATTTC 
CAAAAAGGTT CTGATGCTTT ATATAAAGAA GTCTACACAT TCGAAATGCA GTATCGTGGC 
CGAGAACTAC CAGGGTTTGT GAATTACAAA ACATTTGAGA ACATCATAAG AAGACAAATC 
AAAACCCTGG AAGAACCAGC TATGGAAATG CTTCACAAGG TCACTGAAAT TGTACGGGCT 
GCCTTTACAA CGGTTTCTGA GAAAAATTTC TCTGAGTTTT TTAATCTCCA CAGAACTACC 
AAGTCCAAAC TTGAAGACAT CAGATTAGAA CAGGAAACGG AAGCAGAGAA GGCGATCCGG 
CTTCACTTCC AGATGGAACA AATCATCTAC TGCCAGGACC AAATTTATAG GAAAGCCTTG 
CAGAAGGTGA GAGAGGAGGA AGCTGAGGAG GAGGAGAGGA AGCATGGCAA AAGCAGGTCC 
GCTCAGTCCC CAAATTTACA GACCTCATCC ATGGATGAAA TCTTCCAGCA TCTGAATGCC 
TACCGCCAGG AGGCTCACAA CTGCATCTCC AGCCACATTC CATTGATCAT CCAGTATTTC 
ATCTTGAAGA TGTTTGCTGA GAAGCTGCAG AAGGGCATGC TCCAGCTCCT GCAGGACAAG 
GATTCCTGCA GCTGGCTCCT GAAGGAAAAG AGTGACACCA GTGAGAAGAG GAGATTCCTG 
AAGGAGCGGT TGGCAAGGCT GGCCCAAGCT CAGCGCAGGC TAGCCAAATT CCCTGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

[Differentially expressed genes in the locus associated with relative kidney weight and resting blood pressure in hypertensive rats of the ISIAH strain].
Molekuliarnaia biologiia50(6)944-952(2016 Nov-Dec)
Redina OE,Smolenskaya SE,Fedoseeva LA,Markel AL

Transient dimerization of human MxA promotes GTP hydrolysis, resulting in a mechanical power stroke.
Structure (London, England : 1993)22(10)1433-45(2014 Oct)
Rennie ML,McKelvie SA,Bulloch EM,Kingston RL

In vitro inhibition of the replication of classical swine fever virus by porcine Mx1 protein.
Antiviral research104128-35(2014 Apr)
He DN,Zhang XM,Liu K,Pang R,Zhao J,Zhou B,Chen PY

Interferon-induced antiviral protein MxA interacts with the cellular RNA helicases UAP56 and URH49.
The Journal of biological chemistry286(40)34743-51(2011 Oct)
Wisskirchen C,Ludersdorfer TH,M?ller DA,Moritz E,Pavlovic J

A diverse range of gene products are effectors of the type I interferon antiviral response.
Nature472(7344)481-5(2011 Apr)
Schoggins JW,Wilson SJ,Panis M,Murphy MY,Jones CT,Bieniasz P,Rice CM

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Mx2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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