Ppp1r17 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ppp1r17
Entrez Gene ID	266705
Full Name	protein phosphatase 1, regulatory subunit 17
Synonyms	Gsbs
General protein information	Preferred Names protein phosphatase 1, regulatory subunit 17 Names protein phosphatase 1 regulatory subunit 17 G-substrate
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q24
Summary	substrate of the cGMP-dependent protein kinase and is involved in the inhibition of PP-1 and PP-2A phosphatases [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_153467.1	NP_703197.1	protein phosphatase 1 regulatory subunit 17
XM_006236545.3	XP_006236607.1	protein phosphatase 1 regulatory subunit 17 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	PPP1R17	XP_003431978.2
Mus musculus (house mouse)	Ppp1r17	NP_035283.1
Gallus gallus (chicken)	PPP1R17	XP_004939604.1
Pan troglodytes (chimpanzee)	PPP1R17	XP_001166815.1
Rattus norvegicus (Norway rat)	Ppp1r17	NP_703197.1
Homo sapiens (human)	PPP1R17	NP_006649.2
Bos taurus (cattle)	PPP1R17	XP_002686874.1
	C7orf16	XP_001083835.1
Xenopus tropicalis (tropical clawed frog)	ppp1r17	XP_002940295.1

Gene Ontology
Bibliography

Related articles in PubMed

Retinal G-substrate, potential downstream component of NO/cGMP/PKG pathway, is located in subtype of retinal ganglion cells and amacrine cells with protein phosphatases.
Nakazawa T, Endo S, Shimura M, Kondo M, Ueno S, Tamai M
Brain research. Molecular brain research135(1-2)58-68(2005 Apr)

Thr123 of rat G-substrate contributes to its action as a protein phosphatase inhibitor.
Endo S, Nairn AC, Greengard P, Ito M
Neuroscience research45(1)79-89(2003 Jan)

Phosphorylation-dependent inhibition of protein phosphatase-1 by G-substrate. A Purkinje cell substrate of the cyclic GMP-dependent protein kinase.
Hall KU, Collins SP, Gamm DM, Massa E, DePaoli-Roach AA, Uhler MD
The Journal of biological chemistry274(6)3485-95(1999 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

retinal G-substrate plays a role as a downstream component of the NO-cGMP-PKG pathway. The co-localization of retinal G-substrate with protein Ser/Thr phosphatases suggests that it acts as an endogenous protein phosphatase inhibitor.
Title: Retinal G-substrate, potential downstream component of NO/cGMP/PKG pathway, is located in subtype of retinal ganglion cells and amacrine cells with protein phosphatases.

G-substrate works as protein phosphatase 1 and 2A inhibitor upon phosphorylation by PKG.
Title: Thr123 of rat G-substrate contributes to its action as a protein phosphatase inhibitor.

The following Ppp1r17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ppp1r17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03051	NM_153467.1 Latest version!	Rattus norvegicus protein phosphatase 1, regulatory subunit 17 (Ppp1r17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa03051	XM_006236545.3 Latest version!	Rattus norvegicus protein phosphatase 1, regulatory subunit 17 (Ppp1r17), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ppp1r17 ( NM_153467.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_703197.1 Rattus norvegicus protein phosphatase 1, regulatory subunit 17 (Ppp1r17), mRNA.

Price & Availability↑

CloneID	ORa03051
Clone ID Related Accession (Same CDS sequence)	NM_153467.1 , XM_006236545.3
Accession Version	NM_153467.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Rattus norvegicus(Norway rat)
Product	protein phosphatase 1 regulatory subunit 17
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF294688.1. ##Evidence-Data-START## Transcript exon combination :: AF294688.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCCACTG AGATGATGAC CACTGAGCCA GTGCAGTCTC TGGAGCTTTC AGAAGACATA 
CTAGACAAGC TCGATCCTCA TGGCAGCCAC TCAGATGACC TTTCAGACCA GTTCATTAAG 
GACTGTGACC TGAAAAAGAA GCCAAGAAAG GGGAAGAATG TACAGGCCAC TCTGAACGTT 
GAGTCCGATC AAAAGAAACC CAGAAGGAAA GATACGCCAG CATTGCACAT CCCACCTTTC 
ATACCAGGTG TGATTTCAGA ACACTTAATT AAAAGATATG ACGTTCAAGA GAGAATTCCA 
AAGGGCAAAA CAGGTCCAGC TCTTCATAAC ACTGATGTGG AACAGAAAAG GCCAAGGAGA 
AAAGACACAC CTGCCTTCCA TGTGCCTCCC TTTGTTGCAG GTTTGACTCT CCTCGAGGAT 
GAGGGCACCG GAGTGATTAT GGAGGATGAA GAAATGGATG GTGACAAGCT AGCTATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_703197.1
CDS	126..605
Translation	MSTEMMTTEPVQSLELSEDILDKLDPHGSHSDDLSDQFIKDCDLKKKPRKGKNVQATLNVESDQKKPRRKDTPALHIPPFIPGVISEHLIKRYDVQERIPKGKTGPALHNTDVEQKRPRRKDTPAFHVPPFVAGLTLLEDEGTGVIMEDEEMDGDKLAI

Target ORF information:

RefSeq Version	NM_153467.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus protein phosphatase 1, regulatory subunit 17 (Ppp1r17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153467.1

ORF Insert Sequence:

ATGTCCACTG AGATGATGAC CACTGAGCCA GTGCAGTCTC TGGAGCTTTC AGAAGACATA 
CTAGACAAGC TCGATCCTCA TGGCAGCCAC TCAGATGACC TTTCAGACCA GTTCATTAAG 
GACTGTGACC TGAAAAAGAA GCCAAGAAAG GGGAAGAATG TACAGGCCAC TCTGAACGTT 
GAGTCCGATC AAAAGAAACC CAGAAGGAAA GATACGCCAG CATTGCACAT CCCACCTTTC 
ATACCAGGTG TGATTTCAGA ACACTTAATT AAAAGATATG ACGTTCAAGA GAGAATTCCA 
AAGGGCAAAA CAGGTCCAGC TCTTCATAAC ACTGATGTGG AACAGAAAAG GCCAAGGAGA 
AAAGACACAC CTGCCTTCCA TGTGCCTCCC TTTGTTGCAG GTTTGACTCT CCTCGAGGAT 
GAGGGCACCG GAGTGATTAT GGAGGATGAA GAAATGGATG GTGACAAGCT AGCTATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ppp1r17 ( XM_006236545.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006236607.1 Rattus norvegicus protein phosphatase 1, regulatory subunit 17 (Ppp1r17), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa03051
Clone ID Related Accession (Same CDS sequence)	NM_153467.1 , XM_006236545.3
Accession Version	XM_006236545.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	protein phosphatase 1 regulatory subunit 17 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006236545.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCACTG AGATGATGAC CACTGAGCCA GTGCAGTCTC TGGAGCTTTC AGAAGACATA 
CTAGACAAGC TCGATCCTCA TGGCAGCCAC TCAGATGACC TTTCAGACCA GTTCATTAAG 
GACTGTGACC TGAAAAAGAA GCCAAGAAAG GGGAAGAATG TACAGGCCAC TCTGAACGTT 
GAGTCCGATC AAAAGAAACC CAGAAGGAAA GATACGCCAG CATTGCACAT CCCACCTTTC 
ATACCAGGTG TGATTTCAGA ACACTTAATT AAAAGATATG ACGTTCAAGA GAGAATTCCA 
AAGGGCAAAA CAGGTCCAGC TCTTCATAAC ACTGATGTGG AACAGAAAAG GCCAAGGAGA 
AAAGACACAC CTGCCTTCCA TGTGCCTCCC TTTGTTGCAG GTTTGACTCT CCTCGAGGAT 
GAGGGCACCG GAGTGATTAT GGAGGATGAA GAAATGGATG GTGACAAGCT AGCTATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006236607.1
CDS	640..1119
Translation	MSTEMMTTEPVQSLELSEDILDKLDPHGSHSDDLSDQFIKDCDLKKKPRKGKNVQATLNVESDQKKPRRKDTPALHIPPFIPGVISEHLIKRYDVQERIPKGKTGPALHNTDVEQKRPRRKDTPAFHVPPFVAGLTLLEDEGTGVIMEDEEMDGDKLAI

Target ORF information:

RefSeq Version	XM_006236545.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus protein phosphatase 1, regulatory subunit 17 (Ppp1r17), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006236545.3

ORF Insert Sequence:

ATGTCCACTG AGATGATGAC CACTGAGCCA GTGCAGTCTC TGGAGCTTTC AGAAGACATA 
CTAGACAAGC TCGATCCTCA TGGCAGCCAC TCAGATGACC TTTCAGACCA GTTCATTAAG 
GACTGTGACC TGAAAAAGAA GCCAAGAAAG GGGAAGAATG TACAGGCCAC TCTGAACGTT 
GAGTCCGATC AAAAGAAACC CAGAAGGAAA GATACGCCAG CATTGCACAT CCCACCTTTC 
ATACCAGGTG TGATTTCAGA ACACTTAATT AAAAGATATG ACGTTCAAGA GAGAATTCCA 
AAGGGCAAAA CAGGTCCAGC TCTTCATAAC ACTGATGTGG AACAGAAAAG GCCAAGGAGA 
AAAGACACAC CTGCCTTCCA TGTGCCTCCC TTTGTTGCAG GTTTGACTCT CCTCGAGGAT 
GAGGGCACCG GAGTGATTAT GGAGGATGAA GAAATGGATG GTGACAAGCT AGCTATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Retinal G-substrate, potential downstream component of NO/cGMP/PKG pathway, is located in subtype of retinal ganglion cells and amacrine cells with protein phosphatases.
Brain research. Molecular brain research135(1-2)58-68(2005 Apr)
Nakazawa T,Endo S,Shimura M,Kondo M,Ueno S,Tamai M

Thr123 of rat G-substrate contributes to its action as a protein phosphatase inhibitor.
Neuroscience research45(1)79-89(2003 Jan)
Endo S,Nairn AC,Greengard P,Ito M

Phosphorylation-dependent inhibition of protein phosphatase-1 by G-substrate. A Purkinje cell substrate of the cyclic GMP-dependent protein kinase.
The Journal of biological chemistry274(6)3485-95(1999 Feb)
Hall KU,Collins SP,Gamm DM,Massa E,DePaoli-Roach AA,Uhler MD

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Ppp1r17 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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