Csdc2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Csdc2
Entrez Gene ID	266600
Full Name	cold shock domain containing C2
Synonyms	Pippin
General protein information	Preferred Names cold shock domain containing C2 Names cold shock domain-containing protein C2 RNA-binding protein pippin cold shock domain containing C2, RNA binding
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q34
Summary	binds RNA; may bind double stranded RNA [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001170542.1	NP_001164013.1	cold shock domain-containing protein C2

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	csdc2a	NP_001002690.1
Homo sapiens (human)	CSDC2	NP_055275.1
Mus musculus (house mouse)	Csdc2	NP_663448.2
Xenopus tropicalis (tropical clawed frog)	csdc2	NP_001093718.1
Canis lupus familiaris (dog)	CSDC2	XP_538352.4
Bos taurus (cattle)	CSDC2	NP_001070345.1
Gallus gallus (chicken)	CSDC2	XP_422970.2
Rattus norvegicus (Norway rat)	Csdc2	NP_001164013.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification in the rat brain of a set of nuclear proteins interacting with H1? mRNA.
Di Liegro CM, Schiera G, Proia P, Saladino P, Di Liegro I
Neuroscience22971-6(2013 Jan)

Thyroid hormones induce sumoylation of the cold shock domain-containing protein PIPPin in developing rat brain and in cultured neurons.
Bono E, Compagno V, Proia P, Raimondi L, Schiera G, Favaloro V, Campo V, Donatelli M, Di Liegro I
Endocrinology148(1)252-7(2007 Jan)

RNA-binding ability of PIPPin requires the entire protein.
Raimondi L, D'Asaro M, Proia P, Nastasi T, Di Liegro I
Journal of cellular and molecular medicine7(1)35-42(2003 Jan-Mar)

PIPPin is a brain-specific protein that contains a cold-shock domain and binds specifically to H1 degrees and H3.3 mRNAs.
Nastasi T, Scaturro M, Bellafiore M, Raimondi L, Beccari S, Cestelli A, di Liegro I
The Journal of biological chemistry274(34)24087-93(1999 Aug)

PIPPin, a putative RNA-binding protein specifically expressed in the rat brain.
Castiglia D, Scaturro M, Nastasi T, Cestelli A, Di Liegro I
Biochemical and biophysical research communications218(1)390-4(1996 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

significant difference among euthyroid and hypothyroid newborn rats concerns sumoylation of nuclear PIPPin, which is abolished by hypothyroidism
Title: Thyroid hormones induce sumoylation of the cold shock domain-containing protein PIPPin in developing rat brain and in cultured neurons.

Data show that only recombinant proteins that contain all the putative PIPPin domains show RNA-binding ability.
Title: RNA-binding ability of PIPPin requires the entire protein.

The following Csdc2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Csdc2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06302	NM_001170542.1 Latest version!	Rattus norvegicus cold shock domain containing C2 (Csdc2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Csdc2 ( NM_001170542.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001164013.1 Rattus norvegicus cold shock domain containing C2 (Csdc2), mRNA.

Price & Availability↑

CloneID	ORa06302
Clone ID Related Accession (Same CDS sequence)	NM_001170542.1
Accession Version	NM_001170542.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	cold shock domain-containing protein C2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CO405729.1, DY318921.1, CO401519.1, X89962.1 and CK844327.1. ##Evidence-Data-START## Transcript exon combination :: CO405729.1, X89962.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGACATCAG AGTCTACATC ACCTCCGGTG GTGCCACCTC TGCACTCCCC CAAGTCCCCT 
GTCTGGCCCA CTTTCCCCTT CCACAGGGAG AGCAGTAGGA TCTGGGAACG TGGTGGTGGC 
GTCTCTCCTC GGGACCTGCC CAGCCCTTTG CCTACCAAAC GGACCAGGAC ATACTCCGCG 
ACAGCTCGAG CCTCGGCTGG CCCTGTGTTC AAGGGCGTCT GTAAGCAGTT CTCACGCTCC 
CAGGGCCACG GCTTCATCAC GCCTGAGAAT GGCTCCGAGG ACATCTTCGT GCATGTTTCT 
GACATCGAGG GGGAGTACGT GCCCGTAGAA GGAGATGAGG TGACCTACAA GATGTGTCCC 
ATCCCACCCA AGAACCAGAA GTTTCAGGCT GTGGAGGTGG TGCTCACCCA GTTGGCTCCT 
CATACCCCCC ACGAGACATG GTCTGGCCAG GTTGTGGGAT CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001164013.1
CDS	323..787
Translation	MTSESTSPPVVPPLHSPKSPVWPTFPFHRESSRIWERGGGVSPRDLPSPLPTKRTRTYSATARASAGPVFKGVCKQFSRSQGHGFITPENGSEDIFVHVSDIEGEYVPVEGDEVTYKMCPIPPKNQKFQAVEVVLTQLAPHTPHETWSGQVVGS

Target ORF information:

RefSeq Version	NM_001170542.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cold shock domain containing C2 (Csdc2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001170542.1

ORF Insert Sequence:

ATGACATCAG AGTCTACATC ACCTCCGGTG GTGCCACCTC TGCACTCCCC CAAGTCCCCT 
GTCTGGCCCA CTTTCCCCTT CCACAGGGAG AGCAGTAGGA TCTGGGAACG TGGTGGTGGC 
GTCTCTCCTC GGGACCTGCC CAGCCCTTTG CCTACCAAAC GGACCAGGAC ATACTCCGCG 
ACAGCTCGAG CCTCGGCTGG CCCTGTGTTC AAGGGCGTCT GTAAGCAGTT CTCACGCTCC 
CAGGGCCACG GCTTCATCAC GCCTGAGAAT GGCTCCGAGG ACATCTTCGT GCATGTTTCT 
GACATCGAGG GGGAGTACGT GCCCGTAGAA GGAGATGAGG TGACCTACAA GATGTGTCCC 
ATCCCACCCA AGAACCAGAA GTTTCAGGCT GTGGAGGTGG TGCTCACCCA GTTGGCTCCT 
CATACCCCCC ACGAGACATG GTCTGGCCAG GTTGTGGGAT CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification in the rat brain of a set of nuclear proteins interacting with H1? mRNA.
Neuroscience22971-6(2013 Jan)
Di Liegro CM,Schiera G,Proia P,Saladino P,Di Liegro I

Thyroid hormones induce sumoylation of the cold shock domain-containing protein PIPPin in developing rat brain and in cultured neurons.
Endocrinology148(1)252-7(2007 Jan)
Bono E,Compagno V,Proia P,Raimondi L,Schiera G,Favaloro V,Campo V,Donatelli M,Di Liegro I

RNA-binding ability of PIPPin requires the entire protein.
Journal of cellular and molecular medicine7(1)35-42(2003 Jan-Mar)
Raimondi L,D'Asaro M,Proia P,Nastasi T,Di Liegro I

PIPPin is a brain-specific protein that contains a cold-shock domain and binds specifically to H1 degrees and H3.3 mRNAs.
The Journal of biological chemistry274(34)24087-93(1999 Aug)
Nastasi T,Scaturro M,Bellafiore M,Raimondi L,Beccari S,Cestelli A,di Liegro I

PIPPin, a putative RNA-binding protein specifically expressed in the rat brain.
Biochemical and biophysical research communications218(1)390-4(1996 Jan)
Castiglia D,Scaturro M,Nastasi T,Cestelli A,Di Liegro I

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Csdc2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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